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Your search keyword '"Maligres, Peter E."' showing total 10 results
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10 results on '"Maligres, Peter E."'

1. Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19

Author

McIntosh, John A., primary, Benkovics, Tamas, additional, Silverman, Steven M., additional, Huffman, Mark A., additional, Kong, Jongrock, additional, Maligres, Peter E., additional, Itoh, Tetsuji, additional, Yang, Hao, additional, Verma, Deeptak, additional, Pan, Weilan, additional, Ho, Hsing-I, additional, Vroom, Jonathan, additional, Knight, Anders M., additional, Hurtak, Jessica A., additional, Klapars, Artis, additional, Fryszkowska, Anna, additional, Morris, William J., additional, Strotman, Neil A., additional, Murphy, Grant S., additional, Maloney, Kevin M., additional, and Fier, Patrick S., additional

Published
2021
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3. Stereocontrolled preparation of a nonpeptidal (-)-spirobicyclic NK-1 receptor antagonist

Author

Maligres, Peter E., Waters, Marjorie M., Lee, Jaemoon, Reamer, Robert A., Askin, David, Ashwood, Michael S., and Cameron, Mark

Subjects
Chemistry, Organic -- Research, Peptides -- Physiological aspects, Tachykinins -- Physiological aspects, Halides -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the spirobicyclic neurokinin NK-1 receptor antagonist anipod. The synthesis of this antipode has been carried out and the results indicate that the resulting allylic halide bears the cyclopropoxy-substituted aryl group.

Published
2002

4. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods

Author

Klapars, Artis, primary, Chung, John Y. L., additional, Limanto, John, additional, Calabria, Ralph, additional, Campeau, Louis-Charles, additional, Campos, Kevin R., additional, Chen, Wenyong, additional, Dalby, Stephen M., additional, Davis, Tyler A., additional, DiRocco, Daniel A., additional, Hyde, Alan M., additional, Kassim, Amude M., additional, Larsen, Mona Utne, additional, Liu, Guiquan, additional, Maligres, Peter E., additional, Moment, Aaron, additional, Peng, Feng, additional, Ruck, Rebecca T., additional, Shevlin, Michael, additional, Simmons, Bryon L., additional, Song, Zhiguo Jake, additional, Tan, Lushi, additional, Wright, Timothy J., additional, and Zultanski, Susan L., additional

Published
2021
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5. Preparation of (S)-3-carbethoxy-3-benzylpiperidine and the growth hormone secretagogue L-163,540

Author

Maligres, Peter E., Chartrain, Michel M., Upadhyay, Veena, Cohen, Deborah, Reamer, Robert A., Volante, R.P., Askin, David, and Reider, Paul J.

Subjects
Somatotropin -- Research, Organic compounds -- Research, Biological sciences, Chemistry
Abstract

A study was conducted to analyze the synthesis of (S)-3-carbethoxy-3-benzylpiperidine and the growth hormone secretagogue L163,540. Molecular sieves were utilized to dry solvents for anhydrous reactions. Manipulations were performed under an inert environment of nitrogen gas. High performance liquid chromatography was then carried out using a B-03-5 YMC Basic. In addition, silica gel was used to perform flash column chromatography.

Published
1998

6. Enantioselective Synthesis of α-Methyl-β-cyclopropyldihydrocinnamates

Author

Christensen, Melodie, primary, Nolting, Andrew, additional, Shevlin, Michael, additional, Weisel, Mark, additional, Maligres, Peter E., additional, Lee, Joshua, additional, Orr, Robert K., additional, Plummer, Christopher W., additional, Tudge, Matthew T., additional, Campeau, Louis-Charles, additional, and Ruck, Rebecca T., additional

Published
2016
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