1. Feasibility of low-dose CT with model-based iterative image reconstruction in follow-up of patients with testicular cancer
- Author
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Kevin P. Murphy, Lee Crush, Siobhan B. O’Neill, James Foody, Micheál Breen, Adrian Brady, Paul J. Kelly, Derek G. Power, Paul Sweeney, Jackie Bye, Owen J. O’Connor, Michael M. Maher, and Kevin N. O’Regan
- Subjects
Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Purpose: We examine the performance of pure model-based iterative reconstruction with reduced-dose CT in follow-up of patients with early-stage testicular cancer. Methods: Sixteen patients (mean age 35.6 ± 7.4 years) with stage I or II testicular cancer underwent conventional dose (CD) and low-dose (LD) CT acquisition during CT surveillance. LD data was reconstructed with model-based iterative reconstruction (LD–MBIR). Datasets were objectively and subjectively analysed at 8 anatomical levels. Two blinded clinical reads were compared to gold-standard assessment for diagnostic accuracy. Results: Mean radiation dose reduction of 67.1% was recorded. Mean dose measurements for LD–MBIR were: thorax – 66 ± 11 mGy cm (DLP), 1.0 ± 0.2 mSv (ED), 2.0 ± 0.4 mGy (SSDE); abdominopelvic – 128 ± 38 mGy cm (DLP), 1.9 ± 0.6 mSv (ED), 3.0 ± 0.6 mGy (SSDE). Objective noise and signal-to-noise ratio values were comparable between the CD and LD–MBIR images. LD–MBIR images were superior (p
- Published
- 2016
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