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28 results on '"Kayano, Hidekazu"'

4. Chronic Enteropathy Associated with SLCO2A1 with Pachydermoperiostosis

Author

Tsuzuki, Yoshikazu, Aoyagi, Ryutaro, Miyaguchi, Kazuya, Ashitani, Keigo, Ohgo, Hideki, Yamaoka, Minoru, Ishizawa, Keisuke, Kayano, Hidekazu, Hisamatsu, Tadakazu, Umeno, Junji, Hosoe, Naoki, Matsumoto, Takayuki, Nakamoto, Hidetomo, and Imaeda, Hiroyuki

Subjects
pachydermoperiostosis, Male, Osteoarthropathy, Primary Hypertrophic, hemic and lymphatic diseases, Mutation, SLCO2A1, Humans, Organic Anion Transporters, Case Report, Middle Aged, CEAS, Inflammatory Bowel Diseases, Ulcer
Abstract

A 49-year-old man complained of chronic palpitation and shortness of breath, which had recently become exacerbated. A blood examination indicated severe refractory anemia and hypoproteinemia. Physical examinations revealed anemia, a systolic murmur, and spoon nails. Multiple nonspecific ileal ulcers were observed. A pathological examination indicated a small granuloma with CD68-positive histiocytes. He had a deeply wrinkled forehead, chiseled face, and clubbed fingers. Radiography revealed periostosis of the fingers and long bones in the limb. He was diagnosed with pachydermoperiostosis. SLCO2A1 demonstrated a c.1807C>T homo-mutation. He was also diagnosed with SLCO2A1-associated chronic enteropathy and thus was treated with 5-aminosalicylic acid, which temporarily improved the ileal ulcers, anemia, and hypoalbuminemia.

Published
2020

5. Bendamustine-induced rash is associated with a favorable prognosis in patients with indolent B-cell lymphoma

Author

Takahashi, Naoki, primary, Tsukasaki, Kunihiro, additional, Tanae, Ken, additional, Kohri, Mika, additional, Asou, Chie, additional, Okamura, Daisuke, additional, Ishikawa, Maho, additional, Maeda, Tomoya, additional, Kawai, Nobutaka, additional, Matsuda, Akira, additional, Sato, Tsugumi, additional, Kayano, Hidekazu, additional, Arai, Eiichi, additional, and Asou, Norio, additional

Published
2022
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9. Peritoneal keratin granuloma associated with endometrioid adenocarcinoma of the uterine corpus

Author

Kayano Hidekazu, Nagata Koji, Yamaguchi Hiroshi, Ichimura Takaya, Yasuda Masanori, Uehara Keiichiro, Sasaki Atsushi, Murata Shin-ichi, and Shimizu Michio

Subjects
endometrioid adenocarcinoma, peritoneal keratin granuloma, squamous differentiation, uterine corpus, Pathology, RB1-214
Abstract

Abstract We present a 69-year-old woman with a chief complaint of postmenopausal bleeding. She was diagnosed as having an endometrioid adenocarcinoma by biopsy, and underwent a total abdominal hysterectomy. At the time of surgery, granulation tissue-like nodules were found on the peritoneal serosa of the uterus. In the intraoperative cytology of peritoneal washing, atypical cells were noted. The intraoperative frozen section of the peritoneal nodule revealed granulation tissue with proliferating mesothelial cells. Microscopic examination of the permanent section showed keratin granulomas without viable adenocarcinoma cells on the serosal surface of the ovaries, fallopian tubes and broad ligaments. Postoperative chemotherapy was administered. She has been alive with no evidence of recurrence for 6 months postoperatively. It should be noted that the prognosis of cases in peritoneal keratin granuloma without viable cancer cells is favorable, and that the histological examination is essential for its diagnosis.

Published
2011
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14. Epstein–Barr virus-associated hemophagocytic syndrome in a patient with ulcerative colitis during treatment with azathioprine: A case report and review of literature

Author

Miyaguchi, Kazuya, primary, Yamaoka, Minoru, additional, Tsuzuki, Yoshikazu, additional, Ashitani, Keigo, additional, Ohgo, Hideki, additional, Miyagawa, Yoshitaka, additional, Ishizawa, Keisuke, additional, Kayano, Hidekazu, additional, Nakamoto, Hidetomo, additional, and Imaeda, Hiroyuki, additional

Published
2018
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16. A Case of Abdominal Aortic Retroperitoneal and Mesenteric Amyloid Light Chain Amyloidoma

Author

Yokota, Kazuhiro, Kishida, Dai, Kayano, Hidekazu, Yazaki, Masahide, Shimada, Yuki, Akiyama, Yuji, and Mimura, Toshihide

Subjects
Article Subject
Abstract

We report the case of a Japanese woman with amyloid light chain (AL) amyloidoma in the abdominal aortic retroperitoneum and mesentery. Irregular soft tissue mass lesions with calcification in the abdominal aortic retroperitoneum and mesentery were initially detected by computed tomography at another hospital. The lesions gradually compressed the duodenum, causing symptoms of bowel obstruction. The patient was clinically diagnosed with retroperitoneal fibrosis, and prednisolone was administered at a dose of 40 mg/day. However, the lesions did not change in size and her symptoms continued. She was transferred to our hospital and underwent mesenteric biopsy for histopathology using abdominal laparotomy. The histopathological and immunohistological findings of the mesenteric specimen demonstrated lambda light chain deposition. Accordingly, the patient was finally diagnosed with AL amyloidoma with no evidence of systemic amyloidosis. After laparotomy, her general condition worsened because of complications of pneumonia and deep vein thrombosis. She died suddenly from acute myocardial infarction. We have concluded that abdominal aortic retroperitoneal and mesenteric AL amyloidoma may have very poor prognoses in accordance with previous reports. In addition, the size and location of AL amyloidoma directly influence the prognosis. We suggest that early histopathology is important for improving prognosis.

Published
2016
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18. Association of Increased Ring Ssideroblasts with Inferior Survival in Patients with Myelodysplastic Syndrome with Multi-Lineage Dysplasia

Author

Kawabata, Hiroshi, primary, Tohyama, Kaoru, additional, Matsuda, Akira, additional, Araseki, Kayano, additional, Hata, Tomoko, additional, Suzuki, Takahiro, additional, Kayano, Hidekazu, additional, Shinbo, Kei, additional, Usuki, Kensuke, additional, Hangaishi, Akira, additional, Chiba, Shigeru, additional, Masaharu, Nogawa, additional, Arima, Nobuyoshi, additional, Ishikawa, Takayuki, additional, Ozawa, Keiya, additional, Arai, Shunya, additional, Kurokawa, Mineo, additional, and Takaori-Kondo, Akifumi, additional

Published
2016
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19. A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies

Author

Kayano, Hidekazu, Shimada, Tsuneyuki, Wakimoto, Naoki, Nakamura, Yuichi, Bessho, Masami, Yamaguchi, Hiroshi, Sasaki, Atsushi, and Shimizu, Michio

Subjects
Article Subject
Abstract

A 71-year-old Japanese male patient infected with HCV was diagnosed with thrombocytopenia. Histological examination of the bone marrow aspirate showed numerous lymphoid aggregates with Russell bodies. Immunohistochemistry and flow cytometric analysis demonstrated clonal expansion of CD5+ CD23+ B cells. Russell bodies were positive for IgM and lambda immunoglobulin light chain. The patient also underwent gastric biopsy, which revealed Helicobacter pylori (HP) infection. Subsequent eradication of the bacteria resulted in improvement of his thrombocytopenia. The clinical course remained uneventful at 15-month follow-up, consistent with monoclonal B-cell lymphocytosis. The observed clonal expansion with plasmacytic differentiation may have occurred under the influence of HCV with HP infection.

Published
2011
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21. Tu1116 Eosinophilic Infiltration in the Upper Gastrointestinal Tract in Patients With Bronchial Asthma

Author

Imaeda, Hiroyuki, primary, Yamaoka, Minoru, additional, Yoneno, Kazuaki, additional, Ohgo, Hideki, additional, Kobayashi, Takehito, additional, Noguchi, Toru, additional, Uchida, Yoshitaka, additional, Soma, Tomoyuki, additional, Kayano, Hidekazu, additional, Kanazawa, Minoru, additional, Nakamoto, Hidetomo, additional, and Nagata, Makoto, additional

Published
2015
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22. Pyogenic Granuloma of the Ileum Diagnosed by Double-balloon Enteroscopy

Author

Kikuchi, Azusa, primary, Sujino, Tomohisa, additional, Yamaoka, Minoru, additional, Yoneno, Kazuaki, additional, Ohgo, Hideki, additional, Takagi, Makoto, additional, Morioka, Shingo, additional, Hirooka, Eiji, additional, Yamamoto, Keiji, additional, Shinozuka, Nozomi, additional, Honma, Taku, additional, Kayano, Hidekazu, additional, Nakamoto, Hidetomo, additional, and Imaeda, Hiroyuki, additional

Published
2014
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28. A Case ofMonoclonal Lymphoplasmacytosis of the BoneMarrow with IgM-Positive Russell Bodies.

Author

Kayano, Hidekazu, Shimada, Tsuneyuki, Wakimoto, Naoki, Naka, Yuichi, Bessho, Masami, Yamaguchi, Hiroshi, Sasaki, Atsushi, and Shimizu, Michio

Abstract

A 71-year-old Japanese male patient infected with HCV was diagnosed with thrombocytopenia. Histological examination of the bone marrow aspirate showed numerous lymphoid aggregates with Russell bodies. Immunohistochemistry and flow cytometric analysis demonstrated clonal expansion of CD5+ CD23+ B cells. Russell bodies were positive for IgMand lambda immunoglobulin light chain. The patient also underwent gastric biopsy, which revealed Helicobacter pylori (HP) infection. Subsequent eradication of the bacteria resulted in improvement of his thrombocytopenia. The clinical course remained uneventful at 15-month followup, consistent with monoclonal B-cell lymphocytosis. The observed clonal expansion with plasmacytic differentiation may have occurred under the influence of HCV with HP infection. [ABSTRACT FROM AUTHOR]

Published
2011
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