203 results on '"Imetelstat"'
Search Results
2. A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
3. Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy (IMpress)
4. Study to Evaluate Imetelstat (GRN163L) in Subjects With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
5. Expanded Access for Treatment With Imetelstat
6. A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis
7. AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors
8. Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis
9. Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor
10. Management of Patients with Lower-Risk Myelodysplastic Neoplasms (MDS).
11. Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma
12. Imetelstat in intermediate-2 or high-risk myelofibrosis refractory to JAK inhibitor: IMpactMF phase III study design.
13. Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors
14. Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
15. A Phase 2 Trial of AMG 706 or Bevacizumab in Combination With Chemo for Advanced NSCLC
16. AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
17. Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts.
18. To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.
19. Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast Cancer
20. Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma
21. Study to Evaluate Motesanib With or Without Carboplatin/Paclitaxel or Panitumumab in the Treatment of Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
22. Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma
23. Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera (ET/PV)
24. Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast Cancer
25. Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)
26. Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer
27. Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor Malignancies
28. Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma
29. A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer
30. An Open Label Treatment Extension Study of AMG 706
31. A Study of AMG 706 or Bevacizumab, in Combination With Paclitaxel Chemotherapy, as Treatment for Breast Cancer
32. Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
33. AMG 706 and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma
34. Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma
35. Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors
36. Myelosuppression in Patients Treated with the Telomerase Inhibitor Imetelstat Is Not Mediated through Activation of Toll-Like Receptors
37. Oligonucleotides Targeting Telomeres and Telomerase in Cancer.
38. Télomères et télomérase : des cibles toujours pertinentes en oncologie ?
39. Novel therapeutics in myeloproliferative neoplasms
40. Dynamics of mutations in patients with essential thrombocythemia treated with imetelstat
41. Oligonucleotides Targeting Telomeres and Telomerase in Cancer
42. Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis.
43. Novel therapeutics in myeloproliferative neoplasms
44. Characterization of the In Vitro Inhibitory Potential of the Oligonucleotide Imetelstat on Human Cytochrome P450 Enzymes with Predictions of In Vivo Drug-Drug Interactions
45. New drugs for myeloid neoplasms with ring sideroblasts: Luspatercept vs imetelstat
46. Next Generation Therapeutics for the Treatment of Myelofibrosis
47. Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.
48. The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma.
49. A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
50. Targeting telomere biology in acute lymphoblastic leukemia
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