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6. Nudging towards COVID-19 and influenza vaccination uptake in medically at-risk children: EPIC study protocol of randomised controlled trials in Australian paediatric outpatient clinics

Author

Wang, Bing, primary, Andraweera, Prabha, additional, Danchin, Margaret, additional, Blyth, Christopher C, additional, Vlaev, Ivo, additional, Ong, Jason, additional, Dodd, Jodie M, additional, Couper, Jennifer, additional, Sullivan, Thomas R, additional, Karnon, Jonathan, additional, Spurrier, Nicola, additional, Cusack, Michael, additional, Mordaunt, Dylan, additional, Simatos, Dimi, additional, Dekker, Gustaaf, additional, Carlson, Samantha, additional, Tuckerman, Jane, additional, Wood, Nicholas, additional, Whop, Lisa J, additional, and Marshall, Helen, additional

Published
2024
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8. Mesenchymal stem cell secretome ameliorates over-expression of soluble fms-like tyrosine kinase-1 (sFlt-1) and fetal growth restriction (FGR) in animal SLE model

Author

Bachnas, Muhammad Adrianes, primary, Dekker, Gustaaf Albert, additional, Mudigdo, Ambar, additional, Purwanto, Bambang, additional, Sulistyowati, Sri, additional, Dachlan, Erry Gumilar, additional, Akbar, Muhammad Ilham Aldika, additional, Chouw, Angliana, additional, Sartika, Cynthia Retna, additional, and Widjiati, Widjiati, additional

Published
2023
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10. Elevated Maternal Folate Status and Changes in Maternal Prolactin, Placental Lactogen and Placental Growth Hormone Following Folic Acid Food Fortification: Evidence from Two Prospective Pregnancy Cohorts

Author

Jankovic-Karasoulos, Tanja, primary, Smith, Melanie D., additional, Leemaqz, Shalem, additional, Williamson, Jessica, additional, McCullough, Dylan, additional, Arthurs, Anya L., additional, Jones, Lauren A., additional, Bogias, Konstantinos Justin, additional, Mol, Ben W., additional, Dalton, Julia, additional, Dekker, Gustaaf A., additional, and Roberts, Claire T., additional

Published
2023
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16. Uterine conservative–resective surgery for selected placenta accreta spectrum cases: Surgical–vascular control methods

Author

Aryananda, Rozi Aditya, primary, Aditiawarman, Aditiawarman, additional, Gumilar, Khanisyah Erza, additional, Wardhana, Manggala Pasca, additional, Akbar, M. Ilham Aldika, additional, Cininta, Nareswari, additional, Ernawati, Ernawati, additional, Wicaksono, Budi, additional, Joewono, Hermanto Tri, additional, Dachlan, Erry Gumilar, additional, Bachtiar, Citra Aulia, additional, Kurniawati, Devita, additional, Virdayanti, Dian Puspita, additional, Ariani, Grace, additional, Dekker, Gustaaf Albert, additional, and Sulistyono, Agus, additional

Published
2022
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20. Additional file 1 of A prospective registry analysis of psychosocial and metabolic health between women with and without metabolic syndrome after a complicated pregnancy

Author

Aldridge, Emily, Schubert, K. Oliver, Pathirana, Maleesa, Sierp, Susan, Leemaqz, Shalem Y., Roberts, Claire T., Dekker, Gustaaf A., and Arstall, Margaret A.

Abstract

Additional file 1: Supplementary Table 1. Multiple linear regression model estimating difference in PHQ-9 scores between metabolic syndrome status. Supplementary Table 2. Multiple linear regression model estimating difference in GAD-7 scores between metabolic syndrome status.

Published
2022
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32. Teenage pregnancy: trends, characteristics and outcomes in South Australia and Australia

Author

van der Klis, Karin A.M., Westenberg, Leontine, Chan, Annabelle, Dekker, Gustaaf, and Keane, Rosemary J.

Subjects
Australia -- Social aspects, South Australia -- Social aspects, Teenage pregnancy -- Australia, Health
Abstract

Objectives: To describe trends in teenage pregnancy rates in South Australia and Australia in 1970-2000, and the socio-demographic and clinical characteristics and outcomes of teenage women who gave birth in South Australia in 1995-99. Methods: A descriptive study using population-based legislated South Australian perinatal and abortion data, Australian Medicare and hospital morbidity data on abortions, and birth registration rates from the Australian Bureau of Statistics. Results: The teenage pregnancy rate in South Australia fell in the 1970s and 1980s, increased in the 1990s, but is declining at the turn of the century. Teenage abortions exceeded livebirths annually from 1994, and in 2000 the teenage abortion, birth and pregnancy rates were 22.4, 18.3 and 40.8 per 1,000 respectively. The Australian rates, which are an underestimate, follow the South Australian trends and are declining but still much higher than in many western European countries. High socio-economic areas in South Australia have the lowest teenage pregnancy rates but the highest proportion of teenage pregnancies terminated. Teenagers who gave birth were more likely than older women to be Australian-born, Aboriginal, smokers during pregnancy (47% vs. 23%), to attend few antenatal visits, and to have preterm, small-for-gestational-age and low birthweight babies and neonatal deaths. Perinatal mortality has halved among teenagers under 17 years in the past decade. Conclusions and implications: Births to South Australian teenage women are associated with social disadvantage and relatively poor perinatal outcomes, although these have improved. Current strategies are aimed at reducing the incidence of unplanned teenage pregnancy and improving support for pregnant teenagers.

Published
2002

35. Maternal folate, one‐carbon metabolism and pregnancy outcomes

Author

Jankovic‐Karasoulos, Tanja, primary, Furness, Denise L., additional, Leemaqz, Shalem Y., additional, Dekker, Gustaaf A., additional, Grzeskowiak, Luke E., additional, Grieger, Jessica A., additional, Andraweera, Prabha H., additional, McCullough, Dylan, additional, McAninch, Dale, additional, McCowan, Lesley M., additional, Bianco‐Miotto, Tina, additional, and Roberts, Claire T., additional

Published
2020
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40. Linear association between maternal age and spontaneous breech presentation in singleton pregnancies after 32 weeks gestation

Author

Robillard, Pierre-Yves, Boukerrou, Malik, Bonsante, Francesco, Hulsey, Thomas C., Dekker, Gustaaf, Gouyon, Jean-Bernard, Iacobelli, Silvia, Hulsey, Thomas, Centre d'Études Périnatales de l'Océan Indien (CEPOI), Université de La Réunion (UR)-Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), CHU Sud Saint Pierre [Ile de la Réunion], Service de gynécologie-obstétrique [La réunion], Groupe Hospitalier Sud-CHR La réunion, Division of Pediatric Epidemiology, Medical University of South Carolina [Charleston] (MUSC), Head Division of Obstetrics/Gynaecology & Paediatrics, and University of Adelaide

Subjects
Adult, medicine.medical_specialty, Adolescent, [SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Breech presentation, Périnatalité, Humans, Medicine, 030212 general & internal medicine, Young adult, Breech Presentation, Child, ComputingMilieux_MISCELLANEOUS, Retrospective Studies, Gynecology, Fetus, 030219 obstetrics & reproductive medicine, business.industry, Obstetrics, Singleton, Obstetrics and Gynecology, Gestational age, Retrospective cohort study, Middle Aged, medicine.disease, Pediatrics, Perinatology and Child Health, Gestation, Female, business, Reunion, Maternal Age
Abstract

Purpose: To investigate the association between maternal age and spontaneous breech presentation.Material and methods: Fifteen-year observational study over (2001–2015). All consecutive singleton births delivered at the Centre Hospitalier Universitaire Sud Reunion’s maternity. The only single exclusion criterion was uterine malformations (N = 123) women.Results: Of the 60,963 singleton births, there was a linear association (χ2 for linear trend, p

Published
2017

43. A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test

Author

Scioscia, Marco, primary, Dekker, Gustaaf A, additional, Chaouat, Gérard, additional, Dawonauth, Lalita, additional, Dechend, Ralf, additional, Goldman-Wohl, Debra, additional, Gumilar, Erry, additional, Karumanchi, S Ananth, additional, Kell, Douglas B, additional, Rademacher, Thomas W, additional, Robertson, Sarah, additional, Saito, Shigeru, additional, Scherjon, Sicco, additional, Staff, Anne C, additional, Vatish, Manu, additional, and Robillard, Pierre-Yves, additional

Published
2019
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48. Maternal folate, one‐carbon metabolism and pregnancy outcomes.

Author

Jankovic‐Karasoulos, Tanja, Furness, Denise L., Leemaqz, Shalem Y., Dekker, Gustaaf A., Grzeskowiak, Luke E., Grieger, Jessica A., Andraweera, Prabha H., McCullough, Dylan, McAninch, Dale, McCowan, Lesley M., Bianco‐Miotto, Tina, and Roberts, Claire T.

Subjects
THERAPEUTIC use of folic acid, RISK factors of preeclampsia, CARBON metabolism, BIRTH size, BIRTH weight, CONFIDENCE intervals, GESTATIONAL diabetes, DIET, DIETARY supplements, FATHERS, FOLIC acid, FOOD habits, HYPERTENSION in pregnancy, PREMATURE infants, INGESTION, INTERVIEWING, PREGNANCY complications, PREGNANT women, RESEARCH funding, RISK assessment, VITAMIN B12, HOMOCYSTEINE, MULTIPLE regression analysis, SECONDARY analysis, DATA analysis software, SINGLE nucleotide polymorphisms, DESCRIPTIVE statistics, ODDS ratio, GENOTYPES, PREGNANCY outcomes, DISEASE risk factors, PREGNANCY
Abstract

Single nucleotide polymorphisms and pre‐ and peri‐conception folic acid (FA) supplementation and dietary data were used to identify one‐carbon metabolic factors associated with pregnancy outcomes in 3196 nulliparous women. In 325 participants, we also measured circulating folate, vitamin B12 and homocysteine. Pregnancy outcomes included preeclampsia (PE), gestational hypertension (GHT), small for gestational age (SGA), spontaneous preterm birth (sPTB) and gestational diabetes mellitus (GDM). Study findings show that maternal genotype MTHFR A1298C(CC) was associated with increased risk for PE, whereas TCN2 C766G(GG) had a reduced risk for sPTB. Paternal MTHFR A1298C(CC) and MTHFD1 G1958A(AA) genotypes were associated with reduced risk for sPTB, whereas MTHFR C677T(CT) genotype had an increased risk for GHT. FA supplementation was associated with higher serum folate and vitamin B12 concentrations, reduced uterine artery resistance index and increased birth weight. Women who supplemented with <800 μg daily FA at 15‐week gestation had a higher incidence of PE (10.3%) compared with women who did not supplement (6.1%) or who supplemented with ≥800 μg (5.4%) (P <.0001). Higher serum folate levels were found in women who later developed GDM compared with women with uncomplicated pregnancies (Mean ± SD: 37.6 ± 8 nmol L−1 vs. 31.9 ± 11.2, P =.007). Fast food consumption was associated with increased risk for developing GDM, whereas low consumption of green leafy vegetables and fruit were independent risk factors for SGA and GDM and sPTB and SGA, respectively. In conclusion, maternal and paternal genotypes, together with maternal circulating folate and homocysteine concentrations, and pre‐ and early‐pregnancy dietary factors, are independent risk factors for pregnancy complications. [ABSTRACT FROM AUTHOR]

Published
2021
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49. Sex- and growth-specific characteristics of small for gestational age infants: a prospective cohort study.

Author

van der Vlugt, Eva R., Verburg, Petra E., Leemaqz, Shalem Y., McCowan, Lesley M. E., Poston, Lucilla, Kenny, Louise C., Myers, Jenny, Walker, James J., Dekker, Gustaaf A., and Roberts, Claire T.

Subjects
FETAL growth disorders, HIGH-risk pregnancy, COHORT analysis, INFANTS, FETAL development, LONGITUDINAL method
Abstract

Background: Asymmetric fetal growth and male sex are both associated with adverse neonatal outcome. However, less is known about the influence of asymmetric growth and fetal sex within SGA neonates, a group of infants already at increased risk for adverse neonatal outcomes. The aim of the present study was to provide insight into variance in risk factors for SGA in a fetal sex- and growth symmetry-specific way. Methods: For this prospective, multicenter cohort study, data from the Screening for Pregnancy Endpoints (SCOPE) study were used with 5628 nulliparous participants, of which 633 (11.3%) pregnancies were complicated with SGA and 3376 (60.0%) women had uncomplicated pregnancies. Association between risk factors for SGA, SGA subgroups, and uncomplicated pregnancies were assessed with multivariable analyses. Results: Prevalence of asymmetric growth varied from 45.8% of SGA infants to 5.5% of infants with a customized birthweight > 90th percentile (p < 0.001). Significantly more SGA males had asymmetric growth compared to SGA female infants (51.2% vs 40.4%, p = 0.009). Maternal pre-pregnancy diet and BMI < 20 and ≥ 30 were significantly associated with symmetric SGA but not with asymmetric SGA. Asymmetric SGA infants had not only lower customized birthweight percentile (4.4 (SD 2.8) vs 5.0 (SD 3.0), p < 0.001), but also lower rates of stillbirth (p = 0.041) and less often Apgar scores < 7 (p = 0.060). Conclusions: Among SGA infants, low customized birthweight percentiles and male sex are associated with asymmetric growth. Only symmetric SGA is significantly associated with maternal risk factors in early pregnancy. There is a substantial variance in risk factors and neonatal outcomes for SGA based on growth symmetry, implying a different pathogenesis. Trial registration: ACTRN12607000551493 [ABSTRACT FROM AUTHOR]

Published
2020
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