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1,396 results on '"Cancelliere, A."'

1. Outcomes of mechanical thrombectomy in anticoagulated patients with acute distal and medium vessel stroke.

Author: Salim, Hamza, Musmar, Basel, Adeeb, Nimer, Yedavalli, Vivek, Lakhani, Dhairya, Grewal, Sahibjot, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri, Kühn, Anna, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Tan, Benjamin, Regenhardt, Robert, Heit, Jeremy, Cancelliere, Nicole, Bernstock, Joshua, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João, Harker, Pablo, Radu, Răzvan, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James, Nguyen, Thanh, Varela, Ricardo, Baker, Amanda, Essibayi, Muhammed, Altschul, David, Gonzalez, Nestor, Möhlenbruch, Markus, Costalat, Vincent, Gory, Benjamin, Stracke, Christian, Aziz-Sultan, Mohammad, Hecker, Constantin, Shaikh, Hamza, Liebeskind, David, Pedicelli, Alessandro, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman, Pereira, Vitor, Guenego, Adrien, and Dmytriw, Adam
Subjects: Stroke, anticoagulation, thrombectomy, Humans, Aged, Male, Female, Anticoagulants, Retrospective Studies, Ischemic Stroke, Aged, 80 and over, Thrombectomy, Treatment Outcome, Middle Aged, Stroke
Abstract: BACKGROUND: Stroke remains a major health concern globally, with oral anticoagulants widely prescribed for stroke prevention. The efficacy and safety of mechanical thrombectomy (MT) in anticoagulated patients with distal medium vessel occlusions (DMVO) are not well understood. METHODS: This retrospective analysis involved 1282 acute ischemic stroke (AIS) patients who underwent MT in 37 centers across North America, Asia, and Europe from September 2017 to July 2023. Data on demographics, clinical presentation, treatment specifics, and outcomes were collected. The primary outcomes were functional outcomes at 90 days post-MT, measured by modified Rankin Scale (mRS) scores. Secondary outcomes included reperfusion rates, mortality, and hemorrhagic complications. RESULTS: Of the patients, 223 (34%) were on anticoagulation therapy. Anticoagulated patients were older (median age 78 vs 74 years; p
Published: 2024

2. Endovascular therapy versus medical management in isolated posterior cerebral artery acute ischemic stroke: A multinational multicenter propensity score-weighted study.

Author: Salim, Hamza, Pulli, Benjamin, Yedavalli, Vivek, Musmar, Basel, Adeeb, Nimer, Lakhani, Dhairya, Essibayi, Muhammed, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri, Kühn, Anna, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Grewal, Inayat, Tan, Benjamin, Regenhardt, Robert, Heit, Jeremy, Cancelliere, Nicole, Bernstock, Joshua, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João, Harker, Pablo, Radu, Răzvan, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James, Nguyen, Thanh, Varela, Ricardo, Baker, Amanda, Altschul, David, Gonzalez, Nestor, Möhlenbruch, Markus, Costalat, Vincent, Gory, Benjamin, Stracke, Christian, Aziz-Sultan, Mohammad, Hecker, Constantin, Shaikh, Hamza, Griessenauer, Christoph, Liebeskind, David, Pedicelli, Alessandro, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman, Pereira, Vitor, Wintermark, Max, Guenego, Adrien, and Dmytriw, Adam
Subjects: Acute ischemic stroke, endovascular therapy, medical management, posterior cerebral artery, propensity score analysis
Abstract: BACKGROUND: Despite the proven effectiveness of endovascular therapy (EVT) in acute ischemic strokes (AIS) involving anterior circulation large vessel occlusions, isolated posterior cerebral artery (PCA) occlusions (iPCAo) remain underexplored in clinical trials. This study investigates the comparative effectiveness and safety of EVT against medical management (MM) in patients with iPCAo. METHODS: This multinational, multicenter propensity score-weighted study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, involving 37 centers across North America, Asia, and Europe. We included iPCAo patients treated with either EVT or MM. The primary outcome was the modified Rankin Scale (mRS) at 90 days, with secondary outcomes including functional independence, mortality, and safety profiles such as hemorrhagic complications. RESULTS: A total of 177 patients were analyzed (88 MM and 89 EVT). EVT showed a statistically significant improvement in 90-day mRS scores (OR = 0.55, 95% CI = 0.30-1.00, p = 0.048), functional independence (OR = 2.52, 95% CI = 1.02-6.20, p = 0.045), and a reduction in 90-day mortality (OR = 0.12, 95% CI = 0.03-0.54, p = 0.006) compared to MM. Hemorrhagic complications were not significantly different between the groups. CONCLUSION: EVT for iPCAo is associated with better neurological outcomes and lower mortality compared to MM, without an increased risk of hemorrhagic complications. Nevertheless, these results should be interpreted with caution due to the studys observational design. The findings are hypothesis-generating and highlight the need for future randomized controlled trials to confirm these observations and establish definitive treatment guidelines for this patient population.
Published: 2024

3. Predictive value of follow-up infarct volume on functional outcomes in middle cerebral artery M2 segment vessel occlusion stroke treated with mechanical thrombectomy.

Author: Yedavalli, Vivek, Salim, Hamza, Musmar, Basel, Adeeb, Nimer, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri, Kühn, Anna, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Tan, Benjamin, Regenhardt, Robert, Heit, Jeremy, Cancelliere, Nicole, Bernstock, Joshua, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João, Harker, Pablo, Radu, Răzvan, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James, Nguyen, Thanh, Varela, Ricardo, Baker, Amanda, Essibayi, Muhammed, Altschul, David, Gonzalez, Nestor, Möhlenbruch, Markus, Costalat, Vincent, Gory, Benjamin, Stracke, Christian, Aziz-Sultan, Mohammad, Hecker, Constantin, Shaikh, Hamza, Liebeskind, David, Pedicelli, Alessandro, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman, Pereira, Vitor, Guenego, Adrien, and Dmytriw, Adam
Subjects: Stroke, follow-up infarct volume, mechanical thrombectomy, medium vessel occlusion
Abstract: BACKGROUND: Medium vessel occlusion (MeVO) strokes, particularly affecting the M2 segment of the middle cerebral artery, represent a critical proportion of acute ischemic strokes, posing significant challenges in management and outcome prediction. The efficacy of mechanical thrombectomy (MT) in MeVO stroke may warrant reliable predictors of functional outcomes. This study aimed to investigate the prognostic value of follow-up infarct volume (FIV) for predicting 90-day functional outcomes in MeVO stroke patients undergoing MT. METHODS: This multicenter, retrospective cohort study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, covering patients with acute ischemic stroke due to M2 segment occlusion treated with MT. We examined the relationship between 90-day functional outcomes, measured by the modified Rankin Scale (mRS), and follow-up infarct volume (FIV), assessed through CT or MRI within 12-36 h post-MT. RESULTS: Among 130 participants, specific FIV thresholds were identified with high specificity and sensitivity for predicting outcomes. A FIV ⩽5 ml was highly specific for predicting favorable and excellent outcomes. The optimal cut-off for both prognostications was identified at ⩽15 ml by the Youden Index, with significant reductions in the likelihood of favorable outcomes observed above a 40 ml threshold. Receiver Operator Curve (ROC) analyses confirmed FIV as a superior predictor of functional outcomes compared to traditional recanalization scores, such as final modified thrombolysis in cerebral infarction score (mTICI). Multivariable analysis further highlighted the inverse relationship between FIV and positive functional outcomes. CONCLUSIONS: FIV within 36 h post-MT serves as a potent predictor of 90-day functional outcomes in patients with M2 segment MeVO strokes. Establishing FIV thresholds may aid in the prognostication of stroke outcomes, suggesting a role for FIV in guiding post intervention treatment decisions and informing clinical practice. Future research should focus on validating these findings across diverse patient populations and exploring the integration of FIV measurements with other clinical and imaging markers to enhance outcome prediction accuracy.
Published: 2024

4. Discovery of a dormant 33 solar-mass black hole in pre-release Gaia astrometry

Author: Gaia Collaboration, Panuzzo, P., Mazeh, T., Arenou, F., Holl, B., Caffau, E., Jorissen, A., Babusiaux, C., Gavras, P., Sahlmann, J., Bastian, U., Wyrzykowski, Ł., Eyer, L., Leclerc, N., Bauchet, N., Bombrun, A., Mowlavi, N., Seabroke, G. M., Teyssier, D., Balbinot, E., Helmi, A., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Barbier, A., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Nicolas, C., Randich, S., Sartoretti, P., Smiljanic, R., Tanga, P., Walton, N. A., Aerts, C., Bailer-Jones, C. A. L., Cropper, M., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., Soubiran, C., Thévenin, F., van Leeuwen, F., Andrae, R., Audard, M., Bakker, J., Blomme, R., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Nienartowicz, K., Pailler, F., Riclet, F., Roux, W., Sordo, R., Gracia-Abril, G., Portell, J., Altmann, M., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cacciari, C., Cánovas, H., Carrasco, J. M., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Delchambre, L., Dell'Oro, A., Garcia, E. Fraile, Garabato, D., García-Lario, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hernández, J., Hestroffer, D., Hodgkin, S. T., Jamal, S., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nuñez, Oreshina-Slezak, I., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Weingrill, K., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Ahmed, S., Altavilla, G., Álvarez, M. A., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baig, S., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balog, Z., Barache, C., Barros, M., Barstow, M. A., Bartolomé, S., Bashi, D., Bassilana, J. -L., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Bland-Hawthorn, J., Blazere, A., Boch, T., Bossini, D., Bouquillon, S., Bragaglia, A., Braine, J., Bratsolis, E., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Camut, A., Cancelliere, R., Cantat-Gaudin, T., Guilarte, D. Capilla, Carballo, R., Carlucci, T., Carnerero, M. I., Carretero, J., Carton, S., Casamiquela, L., Casey, A., Castellani, M., Castro-Ginard, A., Ceraj, L., Cesare, V., Charlot, P., Chaudet, C., Chemin, L., Chiavassa, A., Chornay, N., Chosson, D., Cooper, W. J., Cornez, T., Cowell, S., Crosta, M., Crowley, C., Reyes, M. Cruz, Dafonte, C., Ponte, M. Dal, David, M., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Denis, E., Dharmawardena, T. E., Di Giacomo, F., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fatović, M., Fedorets, G., Fernández-Hernández, J., Fernique, P., Figueras, F., Fouron, C., Fragkoudi, F., Gai, M., Galinier, M., Garcia-Serrano, A., García-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomboc, A., Gomez, A., González-Santamaría, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutiérrez-Sánchez, R., Haywood, M., Helmer, A., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jiménez-Arranz, Ó., Campillo, J. Juaristi, Kaczmarek, Z., Kervella, P., Khanna, S., Kontizas, M., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Lambert, S., Lanza, A. F., Lebreton, Y., Lebzelter, T., Leccia, S., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Livanou, E., Lobel, A., López-Miralles, J., Loup, C., Madarász, M., Mahy, L., Mann, R. G., Manteiga, M., Marinoni, S., Marcellino, C. P., Marshall, D. J., Mascarenhas, D., Marchant, J. M., Lozano, J. Martín, Masip, A., Marconi, M., Pina, D. Marín, Polo, L. Martin, Martín-Fleitas, J. M., Mastrobuono-Battisti, A., McMillan, P. J., Meichsner, J. G. Marton, Merc, J., Messina, S., Millar, N. R., Mints, A., Mohamed, D., Molina, D., Molinaro, R., Monguió, M., Montegriffo, P., Monti, L., Mora, A., Morbidelli, R., Morris, D., Mudimadugula, R., Muraveva, T., Musella, I., Nagy, Z., Nardetto, N., Navarrete, C., Oh, S., Ordenovic, C., Orenstein, O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Pawlak, M., Penttilä, A., Pesciullesi, P., Pinamonti, M., Plachy, E., Planquart, L., Plum, G., Poggio, E., Pourbaix, D., Price-Whelan, A. M., Pulone, L., Rabin, V., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robert, G., Robichon, N., Robin, C., Romero-Gómez, M., Rowell, N., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Sellés, A. Sagristà, Sanna, N., Santoveña, R., Sarasso, M., Sarmiento, M. H., Riera, C. Sarrate, Sciacca, E., Ségransan, D., Semczuk, M., Shahaf, S., Siebert, A., Slezak18, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmüller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Teixeira, R., Tepper-Garcia, T., Thuillot, W., Tolomei, L., Tonello, N., Torra, F., Elipe, G. Torralba, Trabucchi, M., Trentin, E., Tsantaki, M., Turon, C., Ulla, A., Unger, N., Valtchanov, I., Vanel, O., Vecchiato, A., Vicente, D., Villar, E., Weiler, M., Zhao, H., Zorec, J., Zucker, S., Župić, A., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - Solar and Stellar Astrophysics
Abstract: Gravitational waves from black-hole merging events have revealed a population of extra-galactic BHs residing in short-period binaries with masses that are higher than expected based on most stellar evolution models - and also higher than known stellar-origin black holes in our Galaxy. It has been proposed that those high-mass BHs are the remnants of massive metal-poor stars. Gaia astrometry is expected to uncover many Galactic wide-binary systems containing dormant BHs, which may not have been detected before. The study of this population will provide new information on the BH-mass distribution in binaries and shed light on their formation mechanisms and progenitors. As part of the validation efforts in preparation for the fourth Gaia data release (DR4), we analysed the preliminary astrometric binary solutions, obtained by the Gaia Non-Single Star pipeline, to verify their significance and to minimise false-detection rates in high-mass-function orbital solutions. The astrometric binary solution of one source, Gaia BH3, implies the presence of a 32.70 \pm 0.82 M\odot BH in a binary system with a period of 11.6 yr. Gaia radial velocities independently validate the astrometric orbit. Broad-band photometric and spectroscopic data show that the visible component is an old, very metal-poor giant of the Galactic halo, at a distance of 590 pc. The BH in the Gaia BH3 system is more massive than any other Galactic stellar-origin BH known thus far. The low metallicity of the star companion supports the scenario that metal-poor massive stars are progenitors of the high-mass BHs detected by gravitational-wave telescopes. The Galactic orbit of the system and its metallicity indicate that it might belong to the Sequoia halo substructure. Alternatively, and more plausibly, it could belong to the ED-2 stream, which likely originated from a globular cluster that had been disrupted by the Milky Way., Comment: 23 pages, accepted fro publication in A&A Letters. New version with small fixes
Published: 2024
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5. Incidence and clinical outcomes of perforations during mechanical thrombectomy for medium vessel occlusion in acute ischemic stroke: A retrospective, multicenter, and multinational study.

Author: Dmytriw, Adam, Musmar, Basel, Salim, Hamza, Ghozy, Sherief, Siegler, James, Kobeissi, Hassan, Shaikh, Hamza, Khalife, Jane, Abdalkader, Mohamad, Klein, Piers, Nguyen, Thanh, Heit, Jeremy, Regenhardt, Robert, Cancelliere, Nicole, Bernstock, Joshua, Naamani, Kareem, Amllay, Abdelaziz, Meyer, Lukas, Dusart, Anne, Bellante, Flavio, Forestier, Géraud, Rouchaud, Aymeric, Saleme, Suzana, Mounayer, Charbel, Fiehler, Jens, Kühn, Anna, Puri, Ajit, Dyzmann, Christian, Kan, Peter, Colasurdo, Marco, Marnat, Gaultier, Berge, Jérôme, Barreau, Xavier, Sibon, Igor, Nedelcu, Simona, Henninger, Nils, Marotta, Thomas, Stapleton, Christopher, Rabinov, James, Ota, Takahiro, Dofuku, Shogo, Yeo, Leonard, Tan, Benjamin, Gopinathan, Anil, Martinez-Gutierrez, Juan, Salazar-Marioni, Sergio, Sheth, Sunil, Renieri, Leonardo, Capirossi, Carolina, Mowla, Ashkan, Chervak, Lina, Vagal, Achala, Adeeb, Nimer, Cuellar-Saenz, Hugo, Tjoumakaris, Stavropoula, Jabbour, Pascal, Khandelwal, Priyank, Biswas, Arundhati, Clarençon, Frédéric, Elhorany, Mahmoud, Premat, Kevin, Valente, Iacopo, Pedicelli, Alessandro, Filipe, João, Varela, Ricardo, Quintero-Consuegra, Miguel, Gonzalez, Nestor, Möhlenbruch, Markus, Jesser, Jessica, Costalat, Vincent, Ter Schiphorst, Adrien, Yedavalli, Vivek, Harker, Pablo, Aziz, Yasmin, Gory, Benjamin, Stracke, Christian, Hecker, Constantin, Kadirvel, Ramanathan, Killer-Oberpfalzer, Monika, Griessenauer, Christoph, Thomas, Ajith, Hsieh, Cheng-Yang, Liebeskind, David, Alexandru Radu, Răzvan, Alexandre, Andrea, Tancredi, Illario, Faizy, Tobias, Fahed, Robert, Weyland, Charlotte, Lubicz, Boris, Patel, Aman, Pereira, Vitor, and Guenego, Adrien
Subjects: AIS, MT, MeVo, Stroke, mechanical thrombectomy, perforation, Humans, Ischemic Stroke, Male, Retrospective Studies, Female, Aged, Middle Aged, Incidence, Thrombectomy, Treatment Outcome, Aged, 80 and over
Abstract: BACKGROUND: Mechanical thrombectomy (MT) has revolutionized the treatment of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), but its efficacy and safety in medium vessel occlusion (MeVO) remain less explored. This multicenter, retrospective study aims to investigate the incidence and clinical outcomes of vessel perforations (confirmed by extravasation during an angiographic series) during MT for AIS caused by MeVO. METHODS: Data were collected from 37 academic centers across North America, Asia, and Europe between September 2017 and July 2021. A total of 1373 AIS patients with MeVO underwent MT. Baseline characteristics, procedural details, and clinical outcomes were analyzed. RESULTS: The incidence of vessel perforation was 4.8% (66/1373). Notably, our analysis indicates variations in perforation rates across different arterial segments: 8.9% in M3 segments, 4.3% in M2 segments, and 8.3% in A2 segments (p = 0.612). Patients with perforation had significantly worse outcomes, with lower rates of favorable angiographic outcomes (TICI 2c-3: 23% vs 58.9%, p
Published: 2024

6. First pass effect as an independent predictor of functional outcomes in medium vessel occlusions: An analysis of an international multicenter study.

Author: Radu, Răzvan, Costalat, Vincent, Fahed, Robert, Ghozy, Sherief, Siegler, James, Shaikh, Hamza, Khalife, Jane, Abdalkader, Mohamad, Klein, Piers, Nguyen, Thanh, Heit, Jeremy, Sweid, Ahmad, El Naamani, Kareem, Regenhardt, Robert, Diestro, Jose, Cancelliere, Nicole, Amllay, Abdelaziz, Meyer, Lukas, Dusart, Anne, Bellante, Flavio, Forestier, Géraud, Rouchaud, Aymeric, Saleme, Suzana, Mounayer, Charbel, Fiehler, Jens, Kühn, Anna, Puri, Ajit, Dyzmann, Christian, Kan, Peter, Colasurdo, Marco, Marnat, Gaultier, Berge, Jérôme, Barreau, Xavier, Sibon, Igor, Nedelcu, Simona, Henninger, Nils, Kyheng, Maéva, Marotta, Thomas, Stapleton, Christopher, Rabinov, James, Ota, Takahiro, Dofuku, Shogo, Yeo, Leonard, Tan, Benjamin, Martinez-Gutierrez, Juan, Salazar-Marioni, Sergio, Sheth, Sunil, Renieri, Leonardo, Capirossi, Carolina, Mowla, Ashkan, Tjoumakaris, Stavropoula, Jabbour, Pascal, Khandelwal, Priyank, Biswas, Arundhati, Clarençon, Frédéric, Elhorany, Mahmoud, Premat, Kevin, Valente, Iacopo, Pedicelli, Alessandro, Pedro Filipe, João, Varela, Ricardo, Quintero-Consuegra, Miguel, Gonzalez, Nestor, Möhlenbruch, Markus, Jesser, Jessica, Tancredi, Illario, Ter Schiphorst, Adrien, Yedavalli, Vivek, Harker, Pablo, Chervak, Lina, Aziz, Yasmin, Gory, Benjamin, Paul Stracke, Christian, Hecker, Constantin, Killer-Oberpfalzer, Monika, Griessenauer, Christoph, Thomas, Ajith, Hsieh, Cheng-Yang, Liebeskind, David, Alexandre, Andrea, Faizy, Tobias, Weyland, Charlotte, Patel, Aman, Pereira, Vitor, Lubicz, Boris, Dmytriw, Adam, and Guenego, Adrien
Subjects: MeVO, Stroke, outcomes research, reperfusion, thrombectomy, Humans, Stroke, Brain Ischemia, Retrospective Studies, Thrombectomy, Treatment Outcome, Intracranial Hemorrhages
Abstract: INTRODUCTION: First pass effect (FPE), achievement of complete recanalization (mTICI 2c/3) with a single pass, is a significant predictor of favorable outcomes for endovascular treatment (EVT) in large vessel occlusion stroke (LVO). However, data concerning the impact on functional outcomes and predictors of FPE in medium vessel occlusions (MeVO) are scarce. PATIENTS AND METHODS: We conducted an international retrospective study on MeVO cases. Multivariable logistic modeling was used to establish independent predictors of FPE. Clinical and safety outcomes were compared between the two study groups (FPE vs non-FPE) using logistic regression models. Good outcome was defined as modified Rankin Scale 0-2 at 3 months. RESULTS: Eight hundred thirty-six patients with a final mTICI ⩾ 2b were included in this analysis. FPE was observed in 302 patients (36.1%). In multivariable analysis, hypertension (aOR 1.55, 95% CI 1.10-2.20) and lower baseline NIHSS score (aOR 0.95, 95% CI 0.93-0.97) were independently associated with an FPE. Good outcomes were more common in the FPE versus non-FPE group (72.8% vs 52.8%), and FPE was independently associated with favorable outcome (aOR 2.20, 95% CI 1.59-3.05). 90-day mortality and intracranial hemorrhage (ICH) were significantly lower in the FPE group, 0.43 (95% CI, 0.25-0.72) and 0.55 (95% CI, 0.39-0.77), respectively. CONCLUSION: Over 2/3 of patients with MeVOs and FPE in our cohort had a favorable outcome at 90 days. FPE is independently associated with favorable outcomes, it may reduce the risk of any intracranial hemorrhage, and 3-month mortality.
Published: 2024

7. Enhancing patient-centred chiropractic care in Canada: identifying barriers, enablers, and strategies through a qualitative needs assessment

Author: To, Daphne, Southerst, Danielle, Atkinson-Graham, Melissa, Yu, Hainan, Connell, Gaelan, Draper, Crystal, and Cancelliere, Carol
Published: 2024
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8. Agreement and concurrent validity between telehealth and in-person diagnosis of musculoskeletal conditions: a systematic review

Author: Oh, David, To, Daphne, Corso, Melissa, Murnaghan, Kent, Yu, Hainan, and Cancelliere, Carol
Published: 2024
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9. Rehabilitation of back pain in the pediatric population: a mixed studies systematic review

Author: Yu, Hainan, Southerst, Danielle, Wong, Jessica J., Verville, Leslie, Connell, Gaelan, Ead, Lauren, Mior, Silvano, Hestbaek, Lise, Swain, Michael, Brunton, Ginny, Shearer, Heather M., Papaconstantinou, Efrosini, To, Daphne, Germann, Darrin, Pohlman, Katie, Cedraschi, Christine, and Cancelliere, Carol
Published: 2024
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10. Infusing 21st-Century Competencies into Scripted Foundation Phase Literacy Lessons

Author: Cancelliere, Semoni, Ramsaroop, Sarita, and Petersen, Nadine
Abstract: Background: Despite large-scale interventions aimed at developing literacy skills, children's reading competence levels in South Africa continue to remain an area of concern. In addition, the need to prepare learners for the increased demands of a fast-changing world of learning and working is gaining attention in educational policy and practice. Aim: Using a qualitative multi-site case study research design, the authors aimed to explore teachers' understanding and enactment of scripted literacy lessons that are designed to promote 21st-century competencies. Setting: Five Grade 1 teachers were selected from four schools, three of which are in periurban and the other in a township area. Methods: Data were generated in two phases across three teaching cycles. In the first phase, lessons were observed and recorded on video. The second phase consisted of stimulated recall interviews (SRIs) in which teachers commented on their recorded lessons. Results: The findings showed that when teachers had relevant prior knowledge of specific competencies, they were better positioned to leverage these as a basis for their lessons. However, the findings also indicated that teachers' entrenched methods and ways of thinking were obstacles for change. Conclusion: Training and development opportunities should pay sufficient attention to the practicalities of changing pedagogies and using scripted lesson plans. Contribution: The findings contribute to knowledge on the affordances and challenges when designing training opportunities aimed at integrating 21st-century competencies into scripted literacy lessons.
Published: 2023

11. Gaia Focused Product Release: Sources from Service Interface Function image analysis -- Half a million new sources in omega Centauri

Author: Gaia Collaboration, Weingrill, K., Mints, A., Castañeda, J., Kostrzewa-Rutkowska, Z., Davidson, M., De Angeli, F., Hernández, J., Torra, F., Ramos-Lerate, M., Babusiaux, C., Biermann, M., Crowley, C., Evans, D. W., Lindegren, L., Martín-Fleitas, J. M., Palaversa, L., Mieres, D. Ruz, Tisanić, K., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Barbier, A., Creevey, O. L., Ducourant, C., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Luri, X., Mignard, F., Randich, S., Sartoretti, P., Smiljanic, R., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Soubiran, C., van Leeuwen, F., Audard, M., Bakker, J., Blomme, R., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Masana, E., Messineo, R., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cheek, N., Clementini, G., Damerdji, Y., de Teodoro, P., Delchambre, L., DellÓro, A., Garcia, E. Fraile, Garabato, D., García-Lario, P., Torres, N. Garralda, Gavras, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hodgkin, S. T., Holl, B., Jamal, S., Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nuñez, Oreshina-Slezak, I., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Antoja, T., Baines, D., Baker, S. G., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bashi, D., Bauchet, N., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Berihuete, A., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Blazere, A., Boch, T., Bombrun, A., Bouquillon, S., Bragaglia, A., Braine, J., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cannizzo, S., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Carretero, J., Carton, S., Casamiquela, L., Castellani, M., Castro-Ginard, A., Cesare, V., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Collins, R., Contursi, G., Cooper, W. J., Cornez, T., Crosta, M., Dafonte, C., de Laverny, P., De Luise, F., De March, R., de Souza, R., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Durán, J., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fatović, M., Fedorets, G., Fernández-Hernández, J., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Gai, M., Galinier, M., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutiérrez-Sánchez, R., Haywood, M., Helmer, A., Helmi, A., Henares, K., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jabłońska, M., Jansen, F., Jiménez-Arranz, Ó., Campillo, J. Juaristi, Khanna, S., Kordopatis, G., Kóspál, Á, Kun, M., Lambert, S., Lanza, A. F., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Lecoeur-Taibi, I., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Loup, C., Mahy, L., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Pina, D. Marín, Marinoni, S., Marshall, D. J., Lozano, J. Martín, Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Meichsner, J., Messina, S., Michalik, D., Millar, N. R., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Mowlavi, N., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Nieto, S., Noval, L., Ogden, A., Ordenovic, C., Pagani, C., Pagano, I., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Panem, C., Payne-Wardenaar, S., Pegoraro, L., Penttilä, A., Pesciullesi, P., Piersimoni, A. M., Pinamonti, M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Pourbaix, D., Prša, A., Pulone, L., Racero, E., Rainer, M., Raiteri, C. M., Ramos, P., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, C., Romero-Gómez, M., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Riera, C. Sarrate, Sciacca, E., Segovia, J. C., Ségransan, D., Shahaf, S., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spina, L., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmüller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Elipe, G. Torralba, Trabucchi, M., Tsantaki, M., Ulla, A., Unger, N., Vanel, O., Vecchiato, A., Vicente, D., Voutsinas, S., Weiler, M., Wyrzykowski, Ł., Zhao, H., Zorec, J., Zwitter, T., Balaguer-Núñez, L., Leclerc, N., Morgenthaler, S., Robert, G., and Zucker, S.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract: Gaia's readout window strategy is challenged by very dense fields in the sky. Therefore, in addition to standard Gaia observations, full Sky Mapper (SM) images were recorded for nine selected regions in the sky. A new software pipeline exploits these Service Interface Function (SIF) images of crowded fields (CFs), making use of the availability of the full two-dimensional (2D) information. This new pipeline produced half a million additional Gaia sources in the region of the omega Centauri ($\omega$ Cen) cluster, which are published with this Focused Product Release. We discuss the dedicated SIF CF data reduction pipeline, validate its data products, and introduce their Gaia archive table. Our aim is to improve the completeness of the {\it Gaia} source inventory in a very dense region in the sky, $\omega$ Cen. An adapted version of {\it Gaia}'s Source Detection and Image Parameter Determination software located sources in the 2D SIF CF images. We validated the results by comparing them to the public {\it Gaia} DR3 catalogue and external Hubble Space Telescope data. With this Focused Product Release, 526\,587 new sources have been added to the {\it Gaia} catalogue in $\omega$ Cen. Apart from positions and brightnesses, the additional catalogue contains parallaxes and proper motions, but no meaningful colour information. While SIF CF source parameters generally have a lower precision than nominal {\it Gaia} sources, in the cluster centre they increase the depth of the combined catalogue by three magnitudes and improve the source density by a factor of ten. This first SIF CF data publication already adds great value to the {\it Gaia} catalogue. It demonstrates what to expect for the fourth {\it Gaia} catalogue, which will contain additional sources for all nine SIF CF regions.
Published: 2023
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12. Gaia Focused Product Release: A catalogue of sources around quasars to search for strongly lensed quasars

Author: Gaia Collaboration, Krone-Martins, A., Ducourant, C., Galluccio, L., Delchambre, L., Oreshina-Slezak, I., Teixeira, R., Braine, J., Campion, J. -F. Le, Mignard, F., Roux, W., Blazere, A., Pegoraro, L., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Barbier, A., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Randich, S., Sartoretti, P., Smiljanic, R., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Soubiran, C., van Leeuwen, F., Audard, M., Bakker, J., Blomme, R., Castaneda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Fremat, Y., Guerrier, A., Masana, E., Messineo, R., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Seabroke, G. M., Sordo, R., Thevenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Canovas, H., Carry, B., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Dell'Oro, A., Garcia, E. Fraile, Garabato, D., Garcia-Lario, P., Torres, N. Garralda, Gavras, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hernandez, J., Hodgkin, S. T., Holl, B., Jamal, S., Jordan, S., Lanzafame, A. C., Loffler, W., Lorca, A., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nunez, Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Weingrill, K., Abbas, U., Abraham, P., Aramburu, A. Abreu, Aerts, C., Altavilla, G., Alvarez, M. A., Alves, J., Anderson, R. I., Antoja, T., Baines, D., Baker, S. G., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolome, S., Bashi, D., Bauchet, N., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Berihuete, A., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Boch, T., Bombrun, A., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cannizzo, S., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Carretero, J., Carton, S., Casamiquela, L., Castellani, M., Castro-Ginard, A., Cesare, V., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Collins, R., Contursi, G., Cooper, W. J., Cornez, T., Crosta, M., Crowley, C., Dafonte, C., de Laverny, P., De Luise, F., De March, R., de Souza, R., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Duran, J., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fatovic, M., Fedorets, G., Fernandez-Hernandez, J., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Gai, M., Galinier, M., Garcia-Gutierrez, A., Garcia-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., Gonzalez-Nunez, J., Gonzalez-Santamaria, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutierrez-Sanchez, R., Haywood, M., Helmer, A., Helmi, A., Henares, K., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jablonska, M., Jansen, F., Jimenez-Arranz, O., Campillo, J. Juaristi, Khanna, S., Kordopatis, G., Kospal, A., Kostrzewa-Rutkowska, Z., Kun, M., Lambert, S., Lanza, A. F., Lebreton, Y., Lebzelter, T., Leccia, S., Lecoeur-Taibi, I., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Lindstrom, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Loup, C., Mahy, L., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Pina, D. Marin, Marinoni, S., Marshall, D. J., Lozano, J. Martin, Martin-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Meichsner, J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnar, L., Monari, G., Monguio, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Mowlavi, N., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Nieto, S., Noval, L., Ogden, A., Ordenovic, C., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Panem, C., Payne-Wardenaar, S., Penttila, A., Pesciullesi, P., Piersimoni, A. M., Pinamonti, M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Pourbaix, D., Prsa, A., Pulone, L., Racero, E., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reyle, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, C., Romero-Gomez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Nunez, A. Saez, Selles, A. Sagrista, Sahlmann, J., Gimenez, V. Sanchez, Sanna, N., Santovena, R., Sarasso, M., Riera, C. Sarrate, Sciacca, E., Segovia, J. C., Segransan, D., Shahaf, S., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spina, L., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmuller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Tisanic, K., Tolomei, L., Torra, F., Elipe, G. Torralba, Trabucchi, M., Tsantaki, M., Ulla, A., Unger, N., Vanel, O., Vecchiato, A., Vicente, D., Voutsinas, S., Weiler, M., Wyrzykowski, L., Zhao, H., Zorec, J., Zwitter, T., Balaguer-Nunez, L., Leclerc, N., Morgenthaler, S., Robert, G., and Zucker, S.
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: Context. Strongly lensed quasars are fundamental sources for cosmology. The Gaia space mission covers the entire sky with the unprecedented resolution of $0.18$" in the optical, making it an ideal instrument to search for gravitational lenses down to the limiting magnitude of 21. Nevertheless, the previous Gaia Data Releases are known to be incomplete for small angular separations such as those expected for most lenses. Aims. We present the Data Processing and Analysis Consortium GravLens pipeline, which was built to analyse all Gaia detections around quasars and to cluster them into sources, thus producing a catalogue of secondary sources around each quasar. We analysed the resulting catalogue to produce scores that indicate source configurations that are compatible with strongly lensed quasars. Methods. GravLens uses the DBSCAN unsupervised clustering algorithm to detect sources around quasars. The resulting catalogue of multiplets is then analysed with several methods to identify potential gravitational lenses. We developed and applied an outlier scoring method, a comparison between the average BP and RP spectra of the components, and we also used an extremely randomised tree algorithm. These methods produce scores to identify the most probable configurations and to establish a list of lens candidates. Results. We analysed the environment of 3 760 032 quasars. A total of 4 760 920 sources, including the quasars, were found within 6" of the quasar positions. This list is given in the Gaia archive. In 87\% of cases, the quasar remains a single source, and in 501 385 cases neighbouring sources were detected. We propose a list of 381 lensed candidates, of which we identified 49 as the most promising. Beyond these candidates, the associate tables in this Focused Product Release allow the entire community to explore the unique Gaia data for strong lensing studies further., Comment: 35 pages, 60 figures, accepted for publication by Astronomy and Astrophysics
Published: 2023
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13. Gaia Focused Product Release: Radial velocity time series of long-period variables

Author: Gaia Collaboration, Trabucchi, M., Mowlavi, N., Lebzelter, T., Lecoeur-Taibi, I., Audard, M., Eyer, L., García-Lario, P., Gavras, P., Holl, B., de Fombelle, G. Jevardat, Nienartowicz, K., Rimoldini, L., Sartoretti, P., Blomme, R., Frémat, Y., Marchal, O., Damerdji, Y., Brown, A. G. A., Guerrier, A., Panuzzo, P., Katz, D., Seabroke, G. M., Benson, K., Haigron, R., Smith, M., Lobel, A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Barbier, A., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Randich, S., Smiljanic, R., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Lattanzi, M. G., Soubiran, C., van Leeuwen, F., Bakker, J., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Galluccio, L., Masana, E., Messineo, R., Nicolas, C., Pailler, F., Riclet, F., Roux, W., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cheek, N., Clementini, G., Davidson, M., de Teodoro, P., Delchambre, L., Dell'Oro, A., Garcia, E. Fraile, Garabato, D., Torres, N. Garralda, Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hernández, J., Hodgkin, S. T., Jamal, S., Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nuñez, Oreshina-Slezak, I., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Siopis, C., Sozzetti, A., Utrilla, E., van Leeuwen, M., Weingrill, K., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Antoja, T., Baines, D., Baker, S. G., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bashi, D., Bauchet, N., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Berihuete, A., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Blazere, A., Boch, T., Bombrun, A., Bouquillon, S., Bragaglia, A., Braine, J., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cannizzo, S., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Carretero, J., Carton, S., Casamiquela, L., Castellani, M., Castro-Ginard, A., Cesare, V., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Collins, R., Contursi, G., Cooper, W. J., Cornez, T., Crosta, M., Crowley, C., Dafonte, C., David, M., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Durán, J., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fatović, M., Fedorets, G., Fernández-Hernández, J., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Gai, M., Galinier, M., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutiérrez-Sánchez, R., Haywood, M., Helmer, A., Helmi, A., Henares, K., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jabłońska, M., Jansen, F., Jiménez-Arranz, Ó., Campillo, J. Juaristi, Khanna, S., Kordopatis, G., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kun, M., Lambert, S., Lanza, A. F., Campion, J. -F. Le, Lebreton, Y., Leccia, S., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Loup, C., Mahy, L., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Pina, D. Marín, Marinoni, S., Marshall, D. J., Lozano, J. Martín, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Meichsner, J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Nieto, S., Noval, L., Ogden, A., Ordenovic, C., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Panem, C., Payne-Wardenaar, S., Pegoraro, L., Penttilä, A., Pesciullesi, P., Piersimoni, A. M., Pinamonti, M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Pourbaix, D., Prša, A., Pulone, L., Racero, E., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, C., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Riera, C. Sarrate, Sciacca, E., Segovia, J. C., Ségransan, D., Shahaf, S., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spina, L., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmüller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Teixeira, R., Tisanić, K., Tolomei, L., Torra, F., Elipe, G. Torralba, Tsantaki, M., Ulla, A., Unger, N., Vanel, O., Vecchiato, A., Vicente, D., Voutsinas, S., Weiler, M., Wyrzykowski, Ł., Zhao, H., Zorec, J., Zwitter, T., Balaguer-Núñez, L., Leclerc, N., Morgenthaler, S., Robert, G., and Zucker, S.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: The third Gaia Data Release (DR3) provided photometric time series of more than 2 million long-period variable (LPV) candidates. Anticipating the publication of full radial-velocity (RV) in DR4, this Focused Product Release (FPR) provides RV time series for a selection of LPVs with high-quality observations. We describe the production and content of the Gaia catalog of LPV RV time series, and the methods used to compute variability parameters published in the Gaia FPR. Starting from the DR3 LPVs catalog, we applied filters to construct a sample of sources with high-quality RV measurements. We modeled their RV and photometric time series to derive their periods and amplitudes, and further refined the sample by requiring compatibility between the RV period and at least one of the $G$, $G_{\rm BP}$, or $G_{\rm RP}$ photometric periods. The catalog includes RV time series and variability parameters for 9\,614 sources in the magnitude range $6\lesssim G/{\rm mag}\lesssim 14$, including a flagged top-quality subsample of 6\,093 stars whose RV periods are fully compatible with the values derived from the $G$, $G_{\rm BP}$, and $G_{\rm RP}$ photometric time series. The RV time series contain a mean of 24 measurements per source taken unevenly over a duration of about three years. We identify the great most sources (88%) as genuine LPVs, with about half of them showing a pulsation period and the other half displaying a long secondary period. The remaining 12% consists of candidate ellipsoidal binaries. Quality checks against RVs available in the literature show excellent agreement. We provide illustrative examples and cautionary remarks. The publication of RV time series for almost 10\,000 LPVs constitutes, by far, the largest such database available to date in the literature. The availability of simultaneous photometric measurements gives a unique added value to the Gaia catalog (abridged), Comment: 36 pages, 38 figures
Published: 2023

14. Job Shop Scheduling via Deep Reinforcement Learning: a Sequence to Sequence approach

Author: Bonetta, Giovanni, Zago, Davide, Cancelliere, Rossella, and Grosso, Andrea
Subjects: Computer Science - Artificial Intelligence, Computer Science - Machine Learning, Computer Science - Neural and Evolutionary Computing, Mathematics - Combinatorics, I.2.0, I.2.8, I.2.6
Abstract: Job scheduling is a well-known Combinatorial Optimization problem with endless applications. Well planned schedules bring many benefits in the context of automated systems: among others, they limit production costs and waste. Nevertheless, the NP-hardness of this problem makes it essential to use heuristics whose design is difficult, requires specialized knowledge and often produces methods tailored to the specific task. This paper presents an original end-to-end Deep Reinforcement Learning approach to scheduling that automatically learns dispatching rules. Our technique is inspired by natural language encoder-decoder models for sequence processing and has never been used, to the best of our knowledge, for scheduling purposes. We applied and tested our method in particular to some benchmark instances of Job Shop Problem, but this technique is general enough to be potentially used to tackle other different optimal job scheduling tasks with minimal intervention. Results demonstrate that we outperform many classical approaches exploiting priority dispatching rules and show competitive results on state-of-the-art Deep Reinforcement Learning ones.
Published: 2023

15. Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study

Author: Hamza Adel Salim, Vivek Yedavalli, Basel Musmar, Nimer Adeeb, Muhammed Amir Essibayi, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kühn, Jane Khalife, Sherief Ghozy, Luca Scarcia, Benjamin Y.Q. Tan, Benjamin Pulli, Jeremy J. Heit, Robert W. Regenhardt, Nicole M. Cancelliere, Joshua D. Bernstock, Aymeric Rouchaud, Jens Fiehler, Sunil Sheth, Ajit S. Puri, Christian Dyzmann, Marco Colasurdo, Xavier Barreau, Leonardo Renieri, João Pedro Filipe, Pablo Harker, Razvan Alexandru Radu, Thomas R. Marotta, Julian Spears, Takahiro Ota, Ashkan Mowla, Pascal Jabbour, Arundhati Biswas, Frédéric Clarençon, James E. Siegler, Thanh N. Nguyen, Ricardo Varela, Amanda Baker, David Altschul, Nestor R. Gonzalez, Markus A. Möhlenbruch, Vincent Costalat, Benjamin Gory, Christian Paul Stracke, Mohammad Ali Aziz-Sultan, Constantin Hecker, Hamza Shaikh, David S. Liebeskind, Alessandro Pedicelli, Andrea M. Alexandre, Illario Tancredi, Tobias D. Faizy, Erwah Kalsoum, Boris Lubicz, Aman B. Patel, Vitor Mendes Pereira, Adrien Guenego, and Adam A. Dmytriw
Subjects: stroke, mechanical thrombectomy, distal medium vessel occlusions, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Background and Purpose The management of acute ischemic stroke (AIS) due to distal medium vessel occlusion (DMVO) remains uncertain, particularly in comparing the effectiveness of intravenous thrombolysis (IVT) plus mechanical thrombectomy (MT) versus IVT alone. This study aimed to evaluate the safety and efficacy in DMVO patients treated with either MT-IVT or IVT alone. Methods This multinational study analyzed data from 37 centers across North America, Asia, and Europe. Patients with AIS due to DMVO were included, with data collected from September 2017 to July 2023. The primary outcome was functional independence, with secondary outcomes including mortality and safety measures such as types of intracerebral hemorrhage. Results The study involved 1,057 patients before matching, and 640 patients post-matching. Functional outcomes at 90 days showed no significant difference between groups in achieving good functional recovery (modified Rankin Scale 0–1 and 0–2), with adjusted odds ratios (OR) of 1.21 (95% confidence interval [CI] 0.81 to 1.79; P=0.35) and 1.00 (95% CI 0.66 to 1.51; P>0.99), respectively. Mortality rates at 90 days were similar between the two groups (OR 0.75, 95% CI 0.44 to 1.29; P=0.30). The incidence of symptomatic intracerebral hemorrhage was comparable, but any type of intracranial hemorrhage was significantly higher in the MT-IVT group (OR 0.43, 95% CI 0.29 to 0.63; P
Published: 2024
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16. Predictors and Outcomes of Excellent Recanalization Versus Successful Recanalization After Thrombectomy in Proximal and Distal Medium Vessel Occlusion Strokes: A Multinational Study

Author: Vivek Yedavalli, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kühn, Jane Khalife, Sherief Ghozy, Luca Scarcia, Benjamin Y. Q. Tan, Jeremy J. Heit, Robert W. Regenhardt, Nicole M. Cancelliere, Joshua D. Bernstock, Aymeric Rouchaud, Jens Fiehler, Sunil Sheth, Muhammed Amir Essibayi, Ajit S. Puri, Christian Dyzmann, Marco Colasurdo, Xavier Barreau, Leonardo Renieri, João Pedro Filipe, Pablo Harker, Răzvan Alexandru Radu, Mohamad Abdalkader, Piers Klein, Thomas R. Marotta, Julian Spears, Takahiro Ota, Ashkan Mowla, Pascal Jabbour, Arundhati Biswas, Frédéric Clarençon, James E. Siegler, Thanh N. Nguyen, Ricardo Varela, Amanda Baker, David Altschul, Nestor R. Gonzalez, Markus A. Möhlenbruch, Vincent Costalat, Benjamin Gory, Christian Paul Stracke, Mohammad Ali Aziz‐Sultan, Constantin Hecker, Hamza Shaikh, David S. Liebeskind, Alessandro Pedicelli, Andrea M. Alexandre, Illario Tancredi, Tobias D. Faizy, Erwah Kalsoum, Boris Lubicz, Aman B. Patel, Vitor Mendes Pereira, Adrien Guenego, and Adam A. Dmytriw
Subjects: acute ischemic stroke, mechanical thrombectomy, medium vessel occlusions, mTICI score, Neurology. Diseases of the nervous system, RC346-429, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Background Acute ischemic stroke arising from medium vessel occlusions (MeVO) poses substantial challenges in treatment and management. This study aims to elucidate the outcomes and factors contributing to achieving excellent recanalization (modified Thrombolysis in Cerebral Infarction [mTICI] 2c–3) versus successful recanalization (mTICI 2b) in patients with MeVO stroke undergoing mechanical thrombectomy (MT). Methods We conducted a multinational study analyzing data from the MAD‐MT (Multicenter Analysis of Distal Medium Vessel Occlusions: Effect of Mechanical Thrombectomy) registry, encompassing 37 centers across North America, Asia, and Europe, collected between September 2017 and July 2023. The study included acute ischemic stroke patients with MeVO treated with MT, with or without intravenous thrombolysis, who achieved mTICI 2b–3 post‐MT. Results Among 1463 patients with successful recanalization (mTICI 2b–3), 523 achieved mTICI 2b recanalization, and 940 achieved mTICI 2c–3. Distal occlusions exhibited higher odds of excellent recanalization compared with proximal MeVO vessel occlusions (odds ratio, 1.58; 95% CI, 1.17–2.15; P = 0.003). Cardioembolic stroke pathogenesis was associated with a higher likelihood of excellent recanalization (1.67; 95% CI, 1.07–2.59; P = 0.018). Patients achieving mTICI 2c–3 recanalization demonstrated lower initial National Institutes of Health Stroke Scale scores, significant improvements in postprocedural National Institutes of Health Stroke Scale shift, and a higher percentage of favorable 90‐day outcomes compared with those with mTICI 2b. However, no significant difference in 90‐day mortality rates was observed. Conclusion This study underscores that among patients with MeVO stroke with successful recanalization (mTICI 2b–3) there is higher likelihood of achieving excellent recanalization (mTICI 2c–3) in distal occlusions and cardioembolic pathogenesis. mTICI 2c–3 scores post‐MT correlate with improved clinical outcomes compared with mTICI 2b, affirming the superiority of excellent recanalization over successful recanalization in patients with MeVO stroke. Further prospective studies and randomized controlled trials are warranted for validation.
Published: 2024
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17. Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer

Author: Elisa Mariella, Gaia Grasso, Martina Miotto, Kristi Buzo, Nicole Megan Reilly, Pietro Andrei, Pietro Paolo Vitiello, Giovanni Crisafulli, Sabrina Arena, Giuseppe Rospo, Giorgio Corti, Annalisa Lorenzato, Carlotta Cancelliere, Ludovic Barault, Giulia Gionfriddo, Michael Linnebacher, Mariangela Russo, Federica Di Nicolantonio, and Alberto Bardelli
Subjects: biomarkers, colorectal cancer, drug targets, gene expression outliers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Multiple strategies are continuously being explored to expand the drug target repertoire in solid tumors. We devised a novel computational workflow for transcriptome‐wide gene expression outlier analysis that allows the systematic identification of both overexpression and underexpression events in cancer cells. Here, it was applied to expression values obtained through RNA sequencing in 226 colorectal cancer (CRC) cell lines that were also characterized by whole‐exome sequencing and microarray‐based DNA methylation profiling. We found cell models displaying an abnormally high or low expression level for 3533 and 965 genes, respectively. Gene expression abnormalities that have been previously associated with clinically relevant features of CRC cell lines were confirmed. Moreover, by integrating multi‐omics data, we identified both genetic and epigenetic alternations underlying outlier expression values. Importantly, our atlas of CRC gene expression outliers can guide the discovery of novel drug targets and biomarkers. As a proof of concept, we found that CRC cell lines lacking expression of the MTAP gene are sensitive to treatment with a PRMT5‐MTA inhibitor (MRTX1719). Finally, other tumor types may also benefit from this approach.
Published: 2024
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18. Differential effect of asparagine and glutamine removal on three adenocarcinoma cell lines

Author: Greta Pessino, Leonardo Lonati, Claudia Scotti, Silvia Calandra, Ornella Cazzalini, Ombretta Iaria, Andrea Previtali, Giorgio Baiocco, Paola Perucca, Anna Tricarico, Martina Vetro, Lucia Anna Stivala, Carlo Ganini, Marta Cancelliere, Massimo Zucchetti, Isabella Guardamagna, and Maristella Maggi
Subjects: Asparaginase, Cell cycle, Adenocarcinoma, Solid tumors, Renal cell carcinoma, Breast carcinoma, Science (General), Q1-390, Social sciences (General), H1-99
Abstract: Asparagine and glutamine depletion operated by the drug Asparaginase (ASNase) has revolutionized therapy in pediatric patients affected by Acute Lymphoblastic Leukemia (ALL), bringing remissions to a remarkable 90 % of cases. However, the knowledge of the proproliferative role of asparagine in adult and solid tumors is still limited. We have here analyzed the effect of ASNase on three adenocarcinoma cell lines (A549, lung adenocarcinoma, MCF-7, breast cancer, and 786-O, kidney cancer). In contrast to MCF-7 cells, 786-O and A549 cells proved to be a relevant target for cell cycle perturbation by asparagine and glutamine shortage. Indeed, when the cell-cycle was analyzed by flow cytometry, A549 showed a canonical response to asparaginase, 786-O cells, instead, showed a reduction of the percentage of cells in the G1 phase and an increase of those in the S-phase. Despite an increased number of PCNA and RPA70 positive nuclear foci, BrdU and EdU incorporation was absent or strongly delayed in treated 786-O cells, thus indicating a readiness of replication forks unmatched by DNA synthesis. In 786-O asparagine synthetase was reduced following treatment and glutamine synthetase was totally absent. Interestingly, DNA synthesis could be recovered by adding Gln to the medium. MCF-7 cells showed no significant changes in the cell cycle phases, in DNA-bound PCNA and in total PCNA, but a significant increase in ASNS and GS mRNA and protein expression. The collected data suggest that the effect observed on 786-O cells following ASNase treatment could rely on mechanisms which differ from those well-known and described for leukemic blasts, consisting of a complete block in the G1/S transition in proliferating cells and on an increase on non-proliferative (G0) blasts.
Published: 2024
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19. Gaia Data Release 3: Summary of the content and survey properties

Author: Gaia Collaboration, Vallenari, A., Brown, A. G. A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordoørcit, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Reylé, C., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Blazere, A., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Edvardsson, B., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hilger, T., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Jorissen, A., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kontizas, M., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylo, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, L., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We present the third data release of the European Space Agency's Gaia mission, GDR3. The GDR3 catalogue is the outcome of the processing of raw data collected with the Gaia instruments during the first 34 months of the mission by the Gaia Data Processing and Analysis Consortium. The GDR3 catalogue contains the same source list, celestial positions, proper motions, parallaxes, and broad band photometry in the G, G$_{BP}$, and G$_{RP}$ pass-bands already present in the Early Third Data Release. GDR3 introduces an impressive wealth of new data products. More than 33 million objects in the ranges $G_{rvs} < 14$ and $3100
Published: 2022
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20. Gaia Data Release 3: Reflectance spectra of Solar System small bodies

Author: Gaia Collaboration, Galluccio, L., Delbo, M., De Angeli, F., Pauwels, T., Tanga, P., Mignard, F., Cellino, A., Brown, A. G. A., Muinonen, K., Penttila, A., Jordan, S., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castaneda, J., Fabricius, C., Fouesneau, M., Frémat, Y., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nunez, Delchambre, L., Oro, A. Dell, Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janssen, K., de Fombelle, G. Jevardat, Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Osborne, P., Pancino, E., Recio-Blanco, A., Reylé, C., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núnez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núnez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hadczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kordopatis, G., Korn, A. J., Kospál, A, Kostrzewa-Rutkowska, Z., Kruszynska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrom, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocana, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Penalosa, Petit, J. -M., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prsa, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núnez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santovena, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, L., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: The Gaia mission of the European Space Agency (ESA) has been routinely observing Solar System objects (SSOs) since the beginning of its operations in August 2014. The Gaia data release three (DR3) includes, for the first time, the mean reflectance spectra of a selected sample of 60 518 SSOs, primarily asteroids, observed between August 5, 2014, and May 28, 2017. Each reflectance spectrum was derived from measurements obtained by means of the Blue and Red photometers (BP/RP), which were binned in 16 discrete wavelength bands. We describe the processing of the Gaia spectral data of SSOs, explaining both the criteria used to select the subset of asteroid spectra published in Gaia DR3, and the different steps of our internal validation procedures. In order to further assess the quality of Gaia SSO reflectance spectra, we carried out external validation against SSO reflectance spectra obtained from ground-based and space-borne telescopes and available in the literature. For each selected SSO, an epoch reflectance was computed by dividing the calibrated spectrum observed by the BP/RP at each transit on the focal plane by the mean spectrum of a solar analogue. The latter was obtained by averaging the Gaia spectral measurements of a selected sample of stars known to have very similar spectra to that of the Sun. Finally, a mean of the epoch reflectance spectra was calculated in 16 spectral bands for each SSO. The agreement between Gaia mean reflectance spectra and those available in the literature is good for bright SSOs, regardless of their taxonomic spectral class. We identify an increase in the spectral slope of S-type SSOs with increasing phase angle. Moreover, we show that the spectral slope increases and the depth of the 1 um absorption band decreases for increasing ages of S-type asteroid families., Comment: 30 pages, 26 figures
Published: 2022
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21. Gaia Data Release 3: Mapping the asymmetric disc of the Milky Way

Author: Gaia Collaboration, Drimmel, R., Romero-Gomez, M., Chemin, L., Ramos, P., Poggio, E., Ripepi, V., Andrae, R., Blomme, R., Cantat-Gaudin, T., Castro-Ginard, A., Clementini, G., Figueras, F., Fouesneau, M., Fremat, Y., Jardine, K., Khanna, S., Lobel, A., Marshall, D. J., Muraveva, T., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Fabricius, C., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordoørcit, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Reylé, C., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Blazere, A., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Chaoul, L., Charlot, P., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Edvardsson, B., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hilger, T., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Jorissen, A., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Kontizas, M., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylo, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, L., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: With the most recent Gaia data release the number of sources with complete 6D phase space information (position and velocity) has increased to well over 33 million stars, while stellar astrophysical parameters are provided for more than 470 million sources, in addition to the identification of over 11 million variable stars. Using the astrophysical parameters and variability classifications provided in Gaia DR3, we select various stellar populations to explore and identify non-axisymmetric features in the disc of the Milky Way in both configuration and velocity space. Using more about 580 thousand sources identified as hot OB stars, together with 988 known open clusters younger than 100 million years, we map the spiral structure associated with star formation 4-5 kpc from the Sun. We select over 2800 Classical Cepheids younger than 200 million years, which show spiral features extending as far as 10 kpc from the Sun in the outer disc. We also identify more than 8.7 million sources on the red giant branch (RGB), of which 5.7 million have line-of-sight velocities, allowing the velocity field of the Milky Way to be mapped as far as 8 kpc from the Sun, including the inner disc. The spiral structure revealed by the young populations is consistent with recent results using Gaia EDR3 astrometry and source lists based on near infrared photometry, showing the Local (Orion) arm to be at least 8 kpc long, and an outer arm consistent with what is seen in HI surveys, which seems to be a continuation of the Perseus arm into the third quadrant. Meanwhile, the subset of RGB stars with velocities clearly reveals the large scale kinematic signature of the bar in the inner disc, as well as evidence of streaming motions in the outer disc that might be associated with spiral arms or bar resonances. (abridged), Comment: 35 pages, 27 figures, accepted for publication in A&A special Gaia DR3 issue. V2: abstract completed. V3: complete author list and link to data: https://drive.google.com/drive/u/1/folders/1yOJPjYmM7QK5XVsqaiSOTuwDQNti2LlZ
Published: 2022
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22. Gaia Data Release 3: Pulsations in main sequence OBAF-type stars

Author: Gaia Collaboration, De Ridder, J., Ripepi, V., Aerts, C., Palaversa, L., Eyer, L., Holl, B., Audard, M., Rimoldini, L., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hilger, T., Hodgkin, S. T., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Reylé, C., Riello, M., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., de Laverny, P., De Luise, F., De March, R., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: The third Gaia data release provides photometric time series covering 34 months for about 10 million stars. For many of those stars, a characterisation in Fourier space and their variability classification are also provided. This paper focuses on intermediate- to high-mass (IHM) main sequence pulsators M >= 1.3 Msun) of spectral types O, B, A, or F, known as beta Cep, slowly pulsating B (SPB), delta Sct, and gamma Dor stars. These stars are often multi-periodic and display low amplitudes, making them challenging targets to analyse with sparse time series. All datasets used in this analysis are part of the Gaia DR3 data release. The photometric time series were used to perform a Fourier analysis, while the global astrophysical parameters necessary for the empirical instability strips were taken from the Gaia DR3 gspphot tables, and the vsini data were taken from the Gaia DR3 esphs tables. We show that for nearby OBAF-type pulsators, the Gaia DR3 data are precise and accurate enough to pinpoint them in the Hertzsprung-Russell diagram. We find empirical instability strips covering broader regions than theoretically predicted. In particular, our study reveals the presence of fast rotating gravity-mode pulsators outside the strips, as well as the co-existence of rotationally modulated variables inside the strips as reported before in the literature. We derive an extensive period-luminosity relation for delta Sct stars and provide evidence that the relation features different regimes depending on the oscillation period. Finally, we demonstrate how stellar rotation attenuates the amplitude of the dominant oscillation mode of delta Sct stars.
Published: 2022
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23. Gaia Data Release 3: A Golden Sample of Astrophysical Parameters

Author: Gaia Collaboration, Creevey, O. L., Sarro, L. M., Lobel, A., Pancino, E., Andrae, R., Smart, R. L., Clementini, G., Heiter, U., Korn, A. J., Fouesneau, M., Frémat, Y., De Angeli, F., Vallenari, A., Harrison, D. L., Thévenin, F., Reylé, C., Sordo, R., Garofalo, A., Brown, A. G. A., Eyer, L., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Ducourant, C., Evans, D. W., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., Fabricius, C., Galluccio, L., Guerrier, A., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Gavel, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kordopatis, G., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Astrophysics of Galaxies, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: Gaia Data Release 3 (DR3) provides a wealth of new data products for the astronomical community to exploit, including astrophysical parameters for a half billion stars. In this work we demonstrate the high quality of these data products and illustrate their use in different astrophysical contexts. We query the astrophysical parameter tables along with other tables in Gaia DR3 to derive the samples of the stars of interest. We validate our results by using the Gaia catalogue itself and by comparison with external data. We have produced six homogeneous samples of stars with high quality astrophysical parameters across the HR diagram for the community to exploit. We first focus on three samples that span a large parameter space: young massive disk stars (~3M), FGKM spectral type stars (~3M), and UCDs (~20K). We provide these sources along with additional information (either a flag or complementary parameters) as tables that are made available in the Gaia archive. We furthermore identify 15740 bone fide carbon stars, 5863 solar-analogues, and provide the first homogeneous set of stellar parameters of the Spectro Photometric Standard Stars. We use a subset of the OBA sample to illustrate its usefulness to analyse the Milky Way rotation curve. We then use the properties of the FGKM stars to analyse known exoplanet systems. We also analyse the ages of some unseen UCD-companions to the FGKM stars. We additionally predict the colours of the Sun in various passbands (Gaia, 2MASS, WISE) using the solar-analogue sample., Comment: 35 pages, (incl 6 pages references, acknowledgements, affiliations), 37 figures, A&A accepted
Published: 2022
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24. Gaia Data Release 3: The extragalactic content

Author: Gaia Collaboration, Bailer-Jones, C. A. L., Teyssier, D., Delchambre, L., Ducourant, C., Garabato, D., Hatzidimitriou, D., Klioner, S. A., Rimoldini, L., Bellas-Velidis, I., Carballo, R., Carnerero, M. I., Diener, C., Fouesneau, M., Galluccio, L., Gavras, P., Krone-Martins, A., Raiteri, C. M., Teixeira, R., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bastian, U., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Fabricius, C., Frémat, Y., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Altmann, M., Andrae, R., Audard, M., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Reylé, C., Riello, M., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carlucci, T., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Diakite, S., Distefano, E., Dolding, C., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kontizas, M., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M. S., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: The Gaia Galactic survey mission is designed and optimized to obtain astrometry, photometry, and spectroscopy of nearly two billion stars in our Galaxy. Yet as an all-sky multi-epoch survey, Gaia also observes several million extragalactic objects down to a magnitude of G~21 mag. Due to the nature of the Gaia onboard selection algorithms, these are mostly point-source-like objects. Using data provided by the satellite, we have identified quasar and galaxy candidates via supervised machine learning methods, and estimate their redshifts using the low resolution BP/RP spectra. We further characterise the surface brightness profiles of host galaxies of quasars and of galaxies from pre-defined input lists. Here we give an overview of the processing of extragalactic objects, describe the data products in Gaia DR3, and analyse their properties. Two integrated tables contain the main results for a high completeness, but low purity (50-70%), set of 6.6 million candidate quasars and 4.8 million candidate galaxies. We provide queries that select purer sub-samples of these containing 1.9 million probable quasars and 2.9 million probable galaxies (both 95% purity). We also use high quality BP/RP spectra of 43 thousand high probability quasars over the redshift range 0.05-4.36 to construct a composite quasar spectrum spanning restframe wavelengths from 72-100 nm., Comment: Accepted to A&A
Published: 2022
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25. Gaia Data Release 3: Stellar multiplicity, a teaser for the hidden treasure

Author: Gaia Collaboration, Arenou, F., Babusiaux, C., Barstow, M. A., Faigler, S., Jorissen, A., Kervella, P., Mazeh, T., Mowlavi, N., Panuzzo, P., Sahlmann, J., Shahaf, S., Sozzetti, A., Bauchet, N., Damerdji, Y., Gavras, P., Giacobbe, P., Gosset, E., Halbwachs, J. -L., Holl, B., Lattanzi, M. G., Leclerc, N., Morel, T., Pourbaix, D., Fiorentin, P. Re, Sadowski, G., Ségransan, D., Siopis, C., Teyssier, D., Zwitter, T., Planquart, L., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Drimmel, R., Jansen, F., Katz, D., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Nicolas, C., Nienartowicz, K., Pailler, F., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Altmann, M., Andrae, R., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Clementini, G., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hodgkin, S. T., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Reylé, C., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Sarro, L. M., Smith, M., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Bartolomé, S., Bassilana, J. -L., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Blazere, A., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Enke, H., Fabre, C., Fabrizio, M., Fedorets, G., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gerlach, E., Geyer, R., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Khanna, S., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Núñez, A. Sáez, Sellés, A. Sagristà, Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M. S., Sciacca, E., Segol, M., Segovia, J. C., Semeux, D., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., and Zucker, S.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Astrophysics of Galaxies, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The Gaia DR3 Catalogue contains for the first time about eight hundred thousand solutions with either orbital elements or trend parameters for astrometric, spectroscopic and eclipsing binaries, and combinations of them. This paper aims to illustrate the huge potential of this large non-single star catalogue. Using the orbital solutions together with models of the binaries, a catalogue of tens of thousands of stellar masses, or lower limits, partly together with consistent flux ratios, has been built. Properties concerning the completeness of the binary catalogues are discussed, statistical features of the orbital elements are explained and a comparison with other catalogues is performed. Illustrative applications are proposed for binaries across the H-R diagram. The binarity is studied in the RGB/AGB and a search for genuine SB1 among long-period variables is performed. The discovery of new EL CVn systems illustrates the potential of combining variability and binarity catalogues. Potential compact object companions are presented, mainly white dwarf companions or double degenerates, but one candidate neutron star is also presented. Towards the bottom of the main sequence, the orbits of previously-suspected binary ultracool dwarfs are determined and new candidate binaries are discovered. The long awaited contribution of Gaia to the analysis of the substellar regime shows the brown dwarf desert around solar-type stars using true, rather than minimum, masses, and provides new important constraints on the occurrence rates of substellar companions to M dwarfs. Several dozen new exoplanets are proposed, including two with validated orbital solutions and one super-Jupiter orbiting a white dwarf, all being candidates requiring confirmation. Beside binarity, higher order multiple systems are also found., Comment: 60 pages, 60 figures. Accepted for publication in Astronomy & Astrophysics (2022-06-09). The catalogue of binary masses is available for download from the ESA Gaia DR3 Archive and will be available from the CDS/VizieR service
Published: 2022
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26. Gaia Data Release 3: Chemical cartography of the Milky Way

Author: Gaia Collaboration, Recio-Blanco, A., Kordopatis, G., de Laverny, P., Palicio, P. A., Spagna, A., Spina, L., Katz, D., Fiorentin, P. Re, Poggio, E., McMillan, P. J., Vallenari, A., Lattanzi, M. G., Seabroke, G. M., Casamiquela, L., Bragaglia, A., Antoja, T., Bailer-Jones, C. A. L., Andrae, R., Fouesneau, M., Cropper, M., Cantat-Gaudin, T., Heiter, U., Bijaoui, A., Brown, A. G. A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U. L., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bastian, U., Drimmel, R., Jansen, F., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Fabricius, C., Frémat, Y., Galluccio, L., Guerrier, A., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Reylé, C., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Varela, E. Anglada, Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bernet, M., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Edvardsson, B., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., González-Vidal, J. J., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Tonello, N., Torra, F., Torra, J., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: Gaia DR3 opens a new era of all-sky spectral analysis of stellar populations thanks to the nearly 5.6 million stars observed by the RVS and parametrised by the GSP-spec module. The all-sky Gaia chemical cartography allows a powerful and precise chemo-dynamical view of the Milky Way with unprecedented spatial coverage and statistical robustness. First, it reveals the strong vertical symmetry of the Galaxy and the flared structure of the disc. Second, the observed kinematic disturbances of the disc -- seen as phase space correlations -- and kinematic or orbital substructures are associated with chemical patterns that favour stars with enhanced metallicities and lower [alpha/Fe] abundance ratios compared to the median values in the radial distributions. This is detected both for young objects that trace the spiral arms and older populations. Several alpha, iron-peak elements and at least one heavy element trace the thin and thick disc properties in the solar cylinder. Third, young disc stars show a recent chemical impoverishment in several elements. Fourth, the largest chemo-dynamical sample of open clusters analysed so far shows a steepening of the radial metallicity gradient with age, which is also observed in the young field population. Finally, the Gaia chemical data have the required coverage and precision to unveil galaxy accretion debris and heated disc stars on halo orbits through their [alpha/Fe] ratio, and to allow the study of the chemo-dynamical properties of globular clusters. Gaia DR3 chemo-dynamical diagnostics open new horizons before the era of ground-based wide-field spectroscopic surveys. They unveil a complex Milky Way that is the outcome of an eventful evolution, shaping it to the present day (abridged)., Comment: Astronomy and Astrophysics (accepted, in press)
Published: 2022
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27. Prognostic of lithium-ion batteries using a combination of physical modeling and hybrid multi-layer perceptron particle filter

Author: Cancelliere, Francesco, Girard, Sylvain, Bourinet, Jean-Marc, and Broggi, Matteo
Published: 2024
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28. Gaia Early Data Release 3: The celestial reference frame (Gaia-CRF3)

Author: Gaia Collaboration, Klioner, S. A., Lindegren, L., Mignard, F., Hernández, J., Ramos-Lerate, M., Bastian, U., Biermann, M., Bombrun, A., de Torres, A., Gerlach, E., Geyer, R., Hilger, T., Hobbs, D., Lammers, U. L., McMillan, P. J., Steidelmüller, H., Teyssier, D., Raiteri, C. M., Bartolomé, S., Bernet, M., Castañeda, J., Clotet, M., Davidson, M., Fabricius, C., Torres, N. Garralda, González-Vidal, J. J., Portell, J., Rowell, N., Torra, F., Torra, J., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Creevey, O. L., Ducourant, C., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Luri, X., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., De Angeli, F., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Altmann, M., Andrae, R., Audard, M., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., de Teodoro, P., Campos, M. Nuñez, Delchambre, L., Dell'Oro, A., Esquej, P., Fernández-Hernández, J., Fraile, E., Garabato, D., García-Lario, P., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Reylé, C., Riello, M., Rimoldini, L., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Aguado, J. J., Ajaj, M., Aldea-Montero, F., Altavilla, G., Álvarez, M. A., Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bassilana, J. -L., Bauchet, N., Becciani, U., Bellazzini, M., Berihuete, A., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Boch, T., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Burlacu, A., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Chaoul, L., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Comoretto, G., Contursi, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Cropper, M., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Figueras, F., Fournier, Y., Fouron, C., Fragkoudi, F., Gai, M., Garcia-Gutierrez, A., Garcia-Reinaldos, M., García-Torres, M., Garofalo, A., Gavel, A., Gavras, P., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., Granvik, M., Guillout, P., Guiraud, J., Gutiérrez-Sánchez, R., Guy, L. P., Hatzidimitriou, D., Hauser, M., Haywood, M., Helmer, A., Helmi, A., Sarmiento, M. H., Hidalgo, S. L., Hładczuk, N., Holland, G., Huckle, H. E., Jardine, K., Jasniewicz, G., Piccolo, A. Jean-Antoine, Jiménez-Arranz, Ó., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Laizeau, P., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E. L., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Lorca, A., Loup, C., Pardo, P. Madrero, Romeo, A. Magdaleno, Managau, S., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Marcos, J., Santos, M. M. S. Marcos, Pina, D. Marín, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Noval, L., Ocaña, F., Ogden, A., Ordenovic, C., Osinde, J. O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Payne-Wardenaar, S., Esteller, X. Peñalosa, Penttilä, A., Pichon, B., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Rambaux, N., Ramos, P., Fiorentin, P. Re, Regibo, S., Richards, P. J., Diaz, C. Rios, Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, A. C., Robin, C., Roelens, M., Rogues, H. R. O., Rohrbasser, L., Romero-Gómez, M., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Silvelo, A., Slezak, E., Slezak, I., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spina, L., Spoto, F., Steele, I. A., Stephenson, C. A., Süveges, M., Surdej, J., Szabados, L., Szegedi-Elek, E., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Tonello, N., Elipe, G. Torralba, Trabucchi, M., Tsounis, A. T., Turon, C., Ulla, A., Unger, N., Vaillant, M. V., van Dillen, E., van Reeven, W., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., and Zwitter, T.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract: Gaia-CRF3 is the celestial reference frame for positions and proper motions in the third release of data from the Gaia mission, Gaia DR3 (and for the early third release, Gaia EDR3, which contains identical astrometric results). The reference frame is defined by the positions and proper motions at epoch 2016.0 for a specific set of extragalactic sources in the (E)DR3 catalogue. We describe the construction of Gaia-CRF3, and its properties in terms of the distributions in magnitude, colour, and astrometric quality. Compact extragalactic sources in Gaia DR3 were identified by positional cross-matching with 17 external catalogues of quasars (QSO) and active galactic nuclei (AGN), followed by astrometric filtering designed to remove stellar contaminants. Selecting a clean sample was favoured over including a higher number of extragalactic sources. For the final sample, the random and systematic errors in the proper motions are analysed, as well as the radio-optical offsets in position for sources in the third realisation of the International Celestial Reference Frame (ICRF3). The Gaia-CRF3 comprises about 1.6 million QSO-like sources, of which 1.2 million have five-parameter astrometric solutions in Gaia DR3 and 0.4 million have six-parameter solutions. The sources span the magnitude range G = 13 to 21 with a peak density at 20.6 mag, at which the typical positional uncertainty is about 1 mas. The proper motions show systematic errors on the level of 12 ${\mu}$as yr${}^{-1}$ on angular scales greater than 15 deg. For the 3142 optical counterparts of ICRF3 sources in the S/X frequency bands, the median offset from the radio positions is about 0.5 mas, but exceeds 4 mas in either coordinate for 127 sources. We outline the future of the Gaia-CRF in the next Gaia data releases.
Published: 2022
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29. Regularization-based Pruning of Irrelevant Weights in Deep Neural Architectures

Author: Bonetta, Giovanni, Ribero, Matteo, and Cancelliere, Rossella
Subjects: Computer Science - Computation and Language, Computer Science - Artificial Intelligence
Abstract: Deep neural networks exploiting millions of parameters are nowadays the norm in deep learning applications. This is a potential issue because of the great amount of computational resources needed for training, and of the possible loss of generalization performance of overparametrized networks. We propose in this paper a method for learning sparse neural topologies via a regularization technique which identifies non relevant weights and selectively shrinks their norm, while performing a classic update for relevant ones. This technique, which is an improvement of classical weight decay, is based on the definition of a regularization term which can be added to any loss functional regardless of its form, resulting in a unified general framework exploitable in many different contexts. The actual elimination of parameters identified as irrelevant is handled by an iterative pruning algorithm. We tested the proposed technique on different image classification and Natural language generation tasks, obtaining results on par or better then competitors in terms of sparsity and metrics, while achieving strong models compression.
Published: 2022

30. A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity

Author: Erin Sellars, Margarita Savguira, Jie Wu, Sabrina Cancelliere, Mark Jen, Rehna Krishnan, Anne Hakem, Dalia Barsyte-Lovejoy, Razqallah Hakem, Steven A. Narod, Joanne Kotsopoulos, and Leonardo Salmena
Subjects: Pharmacology, Cell biology, Cancer, Science
Abstract: Summary: PARP inhibitors (PARPi) are efficacious in BRCA1-null tumors; however, their utility is limited in tumors with functional BRCA1. We hypothesized that pharmacologically reducing BRCA1 protein levels could enhance PARPi effectiveness in BRCA1 wild-type tumors. To identify BRCA1 downregulating agents, we generated reporter cell lines using CRISPR-mediated editing to tag endogenous BRCA1 protein with HiBiT. These reporter lines enable the sensitive measurement of BRCA1 protein levels by luminescence. Validated reporter cells were used in a pilot screen of epigenetic-modifying probes and a larger screen of more than 6,000 compounds. We identified 7 compounds that could downregulate BRCA1-HiBiT expression and synergize with olaparib. Three compounds, N-acetyl-N-acetoxy chlorobenzenesulfonamide (NANAC), A-443654, and CHIR-124, were validated to reduce BRCA1 protein levels and sensitize breast cancer cells to the toxic effects of olaparib. These results suggest that BRCA1-HiBiT reporter cells hold promise in developing agents to improve the clinical utility of PARPi.
Published: 2024
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31. BRCA-associated hereditary male cancers: can gender affect the prevalence and spectrum of germline pathogenic variants?

Author: Daniele Fanale, Lidia Rita Corsini, Chiara Brando, Ugo Randazzo, Marco Bono, Erika Pedone, Alessandro Perez, Roberta Sciacchitano, Daniela Cancelliere, Paola Piraino, Ambra Giurintano, Tancredi Didier Bazan Russo, Pietro Ferraro, Gaetana Rinaldi, Valeria Spinnato, Vincenzo Gennusa, Gianfranco Pernice, Salvatore Vieni, Gianni Pantuso, Antonio Russo, and Viviana Bazan
Subjects: BRCA1, BRCA2, germline pathogenic variants, HBOC, male breast cancer, melanoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: IntroductionAlthough hereditary male neoplasms are quite rare, individuals harbouring germline BRCA1/2 pathogenic variants (PVs) may have a risk of developing tumours associated with Hereditary Breast and Ovarian Cancer (HBOC) syndrome, including male breast (MBC), prostate (PCa) and pancreatic (PC) cancers, and melanoma. Women and men showed a comparable genetic architecture of cancer susceptibility, but there are some gender-specific features. Since little is known about cancer genetic susceptibility in male population, our study was aimed at investigating the frequency of BRCA1/2 PVs in men with HBOC syndrome-associated tumors, in order to understand whether differences in gender may reflect in the prevalence and spectrum of germline alterations.Patients and methodsWe retrospectively collected and analysed clinical information of 352 HBOC-associated male cancer patients genetically tested for germline BRCA1/2 PVs by Next-Generation Sequencing analysis, enrolled, from February 2018 to January 2024, at the “Regional Center for the prevention, diagnosis and treatment of rare and heredo-familial tumors of adults” of the University-Hospital Policlinico “P. Giaccone” of Palermo (Italy).ResultsOur investigation revealed that 7.4% of patients was carrier of a germline BRCA PV, with an almost total prevalence of BRCA2 alterations. In particular, 65.4% of BRCA-positive patients developed MBC, 19.2% had PC, 11.6% developed PCa, and only 3.8% had melanoma. Specifically, MBC individuals showed a BRCA-associated genetic predisposition in 17% of cases, whereas patients with PCa or PC exhibited a lower frequency of BRCA2 PVs, taking into account the current national criteria for access to germline genetic testing.DiscussionOur study showed a high heterogeneity in prevalence of germline BRCA2 PVs among men which could reflect a potential gender-specific genetic heterogeneity. Therefore, BRCA-associated male tumours could be due to BRCA2 PVs different from those usually detected in women. In the event that it is demonstrated, in future, that male cancers are genetically distinct entities from those female this could improve personalized risk evaluation and guide therapeutic choices for patients of both sexes, in order to obtain a gender equality in cancer care.
Published: 2024
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32. Retrieval-Augmented Transformer-XL for Close-Domain Dialog Generation

Author: Bonetta, Giovanni, Cancelliere, Rossella, Liu, Ding, and Vozila, Paul
Subjects: Computer Science - Computation and Language, Computer Science - Artificial Intelligence
Abstract: Transformer-based models have demonstrated excellent capabilities of capturing patterns and structures in natural language generation and achieved state-of-the-art results in many tasks. In this paper we present a transformer-based model for multi-turn dialog response generation. Our solution is based on a hybrid approach which augments a transformer-based generative model with a novel retrieval mechanism, which leverages the memorized information in the training data via k-Nearest Neighbor search. Our system is evaluated on two datasets made by customer/assistant dialogs: the Taskmaster-1, released by Google and holding high quality, goal-oriented conversational data and a proprietary dataset collected from a real customer service call center. Both achieve better BLEU scores over strong baselines., Comment: The International FLAIRS Conference Proceedings volume 34 issue 1
Published: 2021
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33. Controlling Hallucinations at Word Level in Data-to-Text Generation

Author: Rebuffel, Clément, Roberti, Marco, Soulier, Laure, Scoutheeten, Geoffrey, Cancelliere, Rossella, and Gallinari, Patrick
Subjects: Computer Science - Computation and Language, Computer Science - Artificial Intelligence, Computer Science - Machine Learning, Computer Science - Neural and Evolutionary Computing, 68T50 (Primary), 68T07 (Secondary), 68T05, I.2.6, I.2.7
Abstract: Data-to-Text Generation (DTG) is a subfield of Natural Language Generation aiming at transcribing structured data in natural language descriptions. The field has been recently boosted by the use of neural-based generators which exhibit on one side great syntactic skills without the need of hand-crafted pipelines; on the other side, the quality of the generated text reflects the quality of the training data, which in realistic settings only offer imperfectly aligned structure-text pairs. Consequently, state-of-art neural models include misleading statements - usually called hallucinations - in their outputs. The control of this phenomenon is today a major challenge for DTG, and is the problem addressed in the paper. Previous work deal with this issue at the instance level: using an alignment score for each table-reference pair. In contrast, we propose a finer-grained approach, arguing that hallucinations should rather be treated at the word level. Specifically, we propose a Multi-Branch Decoder which is able to leverage word-level labels to learn the relevant parts of each training instance. These labels are obtained following a simple and efficient scoring procedure based on co-occurrence analysis and dependency parsing. Extensive evaluations, via automated metrics and human judgment on the standard WikiBio benchmark, show the accuracy of our alignment labels and the effectiveness of the proposed Multi-Branch Decoder. Our model is able to reduce and control hallucinations, while keeping fluency and coherence in generated texts. Further experiments on a degraded version of ToTTo show that our model could be successfully used on very noisy settings., Comment: 20 pages, 6 figures, 5 tables (excluding Appendix). Source code: https://github.com/KaijuML/dtt-multi-branch
Published: 2021

34. Evaluation of an Enzyme-Linked Magnetic Electrochemical Assay for Hepatitis a Virus Detection in Drinking and Vegetable Processing Water

Author: Cristine D’Agostino, Rocco Cancelliere, Antonio Ceccarelli, Danila Moscone, Loredana Cozzi, Giuseppina La Rosa, Elisabetta Suffredini, and Laura Micheli
Subjects: HAV, ELIME, screen-printed electrodes, drinking water, vegetable processing water, Biochemistry, QD415-436
Abstract: Globally, waterborne viral infections significantly threaten public health. While current European Union regulations stipulate that drinking water must be devoid of harmful pathogens, they do not specifically address the presence of enteric viruses in water used for irrigation or food production. Traditional virus detection methods rely on molecular biology assays, requiring specialized personnel and laboratory facilities. Here, we describe an electrochemical sandwich enzyme-linked immunomagnetic assay (ELIME) for the detection of the hepatitis A virus (HAV) in water matrices. This method employed screen-printed electrodes as the sensing platform and utilized commercially available pre-activated magnetic beads to provide a robust foundation for the immunological reaction. The ELIME assay demonstrated exceptional analytical performance in only 185 min achieving a detection limit of 0.5 genomic copies per milliliter (g.c./mL) and exhibiting good reproducibility with a relative standard deviation (RSD) of 7% in HAV-spiked drinking and processing water samples. Compared with the real-time RT-qPCR method described in ISO 15216-1, the ELIME assay demonstrated higher sensitivity, although the overall linearity of the method was moderate. These analytical attributes highlight the potential of the ELIME assay as a rapid and viable alternative for HAV detection in water used for agriculture and food processing.
Published: 2024
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35. Gaia Early Data Release 3: The Galactic anticentre

Author: Gaia Collaboration, Antoja, T., McMillan, P., Kordopatis, G., Ramos, P., Helmi, A., Balbinot, E., Cantat-Gaudin, T., Chemin, L., Figueras, F., Jordi, C., Khanna, S., Romero-Gomez, M., Seabroke, G., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Babusiaux, C., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Hutton, A., Jansen, F., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Walton, N. A., Arenou, F., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Castañeda, J., De Angeli, F., Ducourant, C., Fabricius, C., Fouesneau, M., Frémat, Y., Guerra, R., Guerrier, A., Guiraud, J., Piccolo, A. Jean-Antoine, Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Sordo, R., Tanga, P., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Brugaletta, E., Burgess, P. W., Busso, G., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., Delchambre, L., Dell'Oro, A., Fernández-Hernández, J., Galluccio, L., García-Lario, P., Garcia-Reinaldos, M., González-Núñez, J., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Heiter, U., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Manteiga, M., Marchal, O., Marrese, P. M., Moitinho, A., Mora, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Richards, P. J., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Ulla, A., Utrilla, E., van Leeuwen, M., van Reeven, W., Abbas, U., Aramburu, A. Abreu, Accart, S., Aerts, C., Aguado, Ajaj, M., Altavilla, G., Álvarez, M. A., Cid-Fuentes, J. Álvarez, Alves, J., Anderson, J. J. R. I., Varela, E. Anglada, Audard, M., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Baudesson-Stella, A., Becciani, U., Bellazzini, M., Bernet, M., Bertone, S., Bianchi, L., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Bucciarelli, B., Burlacu, A., Busonero, D., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cánovas, H., Carballo, R., Carlucci, T., Carnerero, M. I, Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Sampol, P. Castro, Chaoul, L., Charlot, P., Chiavassa, A., Cioni, M. -R. L., Comoretto, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., deLaverny, P., DeLuise, F., DeMarch, R., DeRidder, J., deSouza, R., de Teodoro, P., de Torres, A., del Peloso, E. F., del Pozo, E., Delgado, A., Delgado, H. E., Delisle, J. -B., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Eappachen, D., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Fouron, C., Fragkoudi, F., Fraile, E., Franke, F., Gai, M., Garabato, D., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomez, A., Gonzalez-Santamaria, I., González-Vidal, J. J., Granvik, M., Gutiérrez-Sánchez, R., Guy, L. P., Hauser, M., Haywood, M., Hidalgo, S. L., Hilger, T., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jasniewicz, G., Jonker, P. G., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Kochoska, A., Kontizas, M., Korn, A. J., Kostrzewa-Rutkowska, Z., Kruszyńska, K., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Fustec, Y. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Pardo, P. Madrero, Managau, S., Mann, R. G., Marchant, J. M., Marconi, M., Santos, M. M. S. Marcos, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Montegriffo, P., Mor, R., Morbidelli, R., Morel, T., Morris, D., Mulone, A. F., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Noval, L., Ordénovic, C., Orrù, G., Osinde, J., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Panahi, A., Pawlak, M., Esteller, X. Peñalosa, Penttilä, A., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Poretti, E., Poujoulet, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rixon, G., Robichon, N., Robin, C., Roelens, M., Rohrbasser, L., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Sellés, A. Sagristà, Sahlmann, J., Salgado, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Siddiqui, H. I., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Szabados, L., Szegedi-Elek, E., Taris, F., Tauran, G., Taylor, M. B., Teixeira, R., Thuillot, W., Tonello, N., Torra, F., Torra, J., Turon, C., Unger, N., Vaillant, M., van Dillen, E., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, L., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., Zurbach, C., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We aim to demonstrate the scientific potential of the Gaia Early Data Release 3 (EDR3) for the study of the Milky Way structure and evolution. We used astrometric positions, proper motions, parallaxes, and photometry from EDR3 to select different populations and components and to calculate the distances and velocities in the direction of the anticentre. We explore the disturbances of the current disc, the spatial and kinematical distributions of early accreted versus in-situ stars, the structures in the outer parts of the disc, and the orbits of open clusters Berkeley 29 and Saurer 1. We find that: i) the dynamics of the Galactic disc are very complex with vertical asymmetries, and new correlations, including a bimodality with disc stars with large angular momentum moving vertically upwards from below the plane, and disc stars with slightly lower angular momentum moving preferentially downwards; ii) we resolve the kinematic substructure (diagonal ridges) in the outer parts of the disc for the first time; iii) the red sequence that has been associated with the proto-Galactic disc that was present at the time of the merger with Gaia-Enceladus-Sausage is currently radially concentrated up to around 14 kpc, while the blue sequence that has been associated with debris of the satellite extends beyond that; iv) there are density structures in the outer disc, both above and below the plane, most probably related to Monoceros, the Anticentre Stream, and TriAnd, for which the Gaia data allow an exhaustive selection of candidate member stars and dynamical study; and v) the open clusters Berkeley~29 and Saurer~1, despite being located at large distances from the Galactic centre, are on nearly circular disc-like orbits. We demonstrate how, once again, the Gaia are crucial for our understanding of the different pieces of our Galaxy and their connection to its global structure and history., Comment: Gaia EDR3 performance verification paper, version 2 closer to published version in A&A, complete list of authors
Published: 2021
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36. Care at a distance: Understanding lived experiences of people with MSK disorders receiving non-pharmacological interventions delivered through synchronous telehealth: A systematic rapid review

Author: Melissa Atkinson-Graham, Ginny Brunton, Carol Cancelliere, Melissa Corso, Annemarie de Zoete, Sidney M Rubinstein, Kent Murnaghan, and Silvano Mior
Subjects: Computer applications to medicine. Medical informatics, R858-859.7
Abstract: Background Little is known about lived experience of synchronous telehealth in patients with musculoskeletal (MSK) disorders. Objective We conducted a rapid systematic review to answer: (1) what are the lived experiences and/or perspectives of people with MSK disorders receiving non-pharmacological interventions delivered through synchronous telehealth; and (2) what clinical implications can be inferred from qualitative studies focusing on lived experiences for how telehealth is delivered in the management of MSK disorders? Data sources A comprehensive search of MEDLINE, CINAHL, PsycINFO, ProQuest, and Google Scholar from June 2010 to July 2023. Eligible qualitative and mixed methods studies capturing lived experiences of adults with MSK disorders receiving non-pharmacological interventions via synchronous telehealth were included. Study methods Systematic rapid review conducted according to WHO guidelines. Titles and abstracts screened by reviewers independently, eligible studies critically appraised, and data was extracted. Themes summarized using the Consolidated Framework for Implementation Research (CFIR). GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research) used to assess confidence in synthesis findings. Results We identified 9782 references, screened 8029, and critically appraised 22, and included 17 studies. There is evidence to suggest that the experience of telehealth prior to and during the pandemic was shaped by (1) patient perception of telehealth, (2) existing relationships with practitioners, (3) availability and accessibility of telehealth technologies, and (4) perceptions about the importance of the role of the physical exam in assessing and treating MSK disorders. Conclusion The five identified implications could be used to inform future research, policy, and strategy development.
Published: 2024
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37. Gaia Early Data Release 3: The astrometric solution

Author: Lindegren, L., Klioner, S. A., Hernández, J., Bombrun, A., Ramos-Lerate, M., Steidelmüller, H., Bastian, U., Biermann, M., de Torres, A., Gerlach, E., Geyer, R., Hilger, T., Hobbs, D., Lammers, U., McMillan, P. J., Stephenson, C. A., Castañeda, J., Davidson, M., Fabricius, C., Gracia-Abril, G., Portell, J., Rowell, N., Teyssier, D., Torra, F., Bartolomé, S., Clotet, M., Garralda, N., González-Vidal, J. J., Torra, J., Abbas, U., Altmann, M., Varela, E. Anglada, Balaguer-Núñez, L., Balog, Z., Barache, C., Becciani, U., Bernet, M., Bertone, S., Bianchi, L., Bouquillon, S., Brown, A. G. A., Bucciarelli, B., Busonero, D., Butkevich, A. G., Buzzi, R., Cancelliere, R., Carlucci, T., Charlot, P., Cioni, M. -R. L., Crosta, M., Crowley, C., del Peloso, E. F., del Pozo, E., Drimmel, R., Esquej, P., Fienga, A., Fraile, E., Gai, M., Garcia-Reinaldos, M., Guerra, R., Hambly, N. C., Hauser, M., Janßen, K., Jordan, S., Kostrzewa-Rutkowska, Z., Lattanzi, M. G., Liao, S., Licata, E., Lister, T. A., Löffler, W., Marchant, J. M., Masip, A., Mignard, F., Mints, A., Molina, D., Mora, A., Morbidelli, R., Murphy, C. P., Pagani, C., Panuzzo, P., Esteller, X. Peñalosa, Poggio, E., Fiorentin, P. Re, Riva, A., Sellés, A. Sagristà, Gimenez, V. Sanchez, Sarasso, M., Sciacca, E., Siddiqui, H. I., Smart, R. L., Souami, D., Spagna, A., Steele, I. A., Taris, F., Utrilla, E., van Reeven, W., and Vecchiato, A.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: Gaia Early Data Release 3 (Gaia EDR3) contains results for 1.812 billion sources in the magnitude range G = 3 to 21 based on observations collected by the European Space Agency Gaia satellite during the first 34 months of its operational phase. We describe the input data, the models, and the processing used for the astrometric content of Gaia EDR3, as well as the validation of these results performed within the astrometry task. The processing broadly followed the same procedures as for Gaia DR2, but with significant improvements to the modelling of observations. For the first time in the Gaia data processing, colour-dependent calibrations of the line- and point-spread functions have been used for sources with well-determined colours from DR2. In the astrometric processing these sources obtained five-parameter solutions, whereas other sources were processed using a special calibration that allowed a pseudocolour to be estimated as the sixth astrometric parameter. Compared with DR2, the astrometric calibration models have been extended, and the spin-related distortion model includes a self-consistent determination of basic-angle variations, improving the global parallax zero point. Gaia EDR3 gives full astrometric data (positions at epoch J2016.0, parallaxes, and proper motions) for 1.468 billion sources (585 million with five-parameter solutions, 882 million with six parameters), and mean positions at J2016.0 for an additional 344 million. Solutions with five parameters are generally more accurate than six-parameter solutions, and are available for 93% of the sources brighter than G = 17 mag. The median uncertainty in parallax and annual proper motion is 0.02-0.03 mas at magnitude G = 9 to 14, and around 0.5 mas at G = 20. Extensive characterisation of the statistical properties of the solutions is provided, including the estimated angular power spectrum of parallax bias from the quasars., Comment: 35 pages, 26 figures. Accepted for publication in Astronomy & Astrophysics
Published: 2020
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38. Gaia Early Data Release 3: The Gaia Catalogue of Nearby Stars

Author: Gaia Collaboration, Smart, R. L., Sarro, L. M., Rybizki, J., Reylé, C., Robin, A. C., Hambly, N. C., Abbas, U., Barstow, M. A., de Bruijne, J. H. J., Bucciarelli, B., Carrasco, J. M., Cooper, W. J., Hodgkin, S. T., Masana, E., Michalik, D., Sahlmann, J., Sozzetti, A., Brown, A. G. A., Vallenari, A., Prusti, T., Babusiaux, C., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Hutton, A., Jansen, F., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Walton, N. A., Arenou, F., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Castañeda, J., De Angeli, F., Ducourant, C., Fabricius, C., Fouesneau, M., Frémat, Y., Guerra, R., Guerrier, A., Guiraud, J., Piccolo, A. Jean-Antoine, Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Tanga, P., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Brugaletta, E., Burgess, P. W., Busso, G., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., Delchambre, L., Dell'Oro, A., Fernández-Hernández, J., Galluccio, L., García-Lario, P., Garcia-Reinaldos, M., González-Núñez, J., Gosset, E., Haigron, R., Halbwachs, J. -L., Harrison, D. L., Hatzidimitriou, D., Heiter, U., Hernández, J., Hestroffer, D., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Manteiga, M., Marchal, O., Marrese, P. M., Moitinho, A., Mora, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Richards, P. J., Riello, M., Rimoldini, L., Roegiers, T., Siopis, C., Smith, M., Ulla, A., Utrilla, E., van Leeuwen, M., van Reeven, W., Aramburu, A. Abreu, Accart, S., Aerts, C., Aguado, J. J., Ajaj, M., Altavilla, G., Álvarez, M. A., Cid-Fuentes, J. Álvarez, Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Audard, M., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Baudesson-Stella, A., Becciani, U., Bellazzini, M., Bernet, M., Bertone, S., Bianchi, L., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Burlacu, A., Busonero, D., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cánovas, H., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I, Casamiquela, L., Castellani, M., Castro-Ginard, A., Sampol, P. Castro, Chaoul, L., Charlot, P., Chemin, L., Chiavassa, A., Cioni, M. -R. L., Comoretto, G., Cornez, T., Cowell, S., Crifo, F., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Teodoro, P., de Torres, A., del Peloso, E. F., del Pozo, E., Delgado, A., Delgado, H. E., Delisle, J. -B., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Eappachen, D., Edvardsson, B., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Figueras, F., Fouron, C., Fragkoudi, F., Fraile, E., Franke, F., Gai, M., Garabato, D., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., Gonzalez-Santamaria, I., González-Vidal, J. J., Granvik, M., Gutiérrez-Sánchez, R., Guy, L. P., Hauser, M., Haywood, M., Helmi, A., Hidalgo, S. L., Hilger, T., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jasniewicz, G., Jonker, P. G., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kochoska, A., Kontizas, M., Kordopatis, G., Korn, A. J., Kostrzewa-Rutkowska, Z., Kruszyńska, K., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Fustec, Y. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Pardo, P. Madrero, Managau, S., Mann, R. G., Marchant, J. M., Marconi, M., Santos, M. M. S. Marcos, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Montegriffo, P., Mor, R., Morbidelli, R., Morel, T., Morris, D., Mulone, A. F., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Noval, L., Ordénovic, C., Orrù, G., Osinde, J., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Panahi, A., Pawlak, M., Esteller, X. Peñalosa, Penttilä, A., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Poretti, E., Poujoulet, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Ripepi, V., Riva, A., Rixon, G., Robichon, N., Robin, C., Roelens, M., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Sellés, A. Sagristà, Salgado, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Slezak, E., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Szabados, L., Szegedi-Elek, E., Taris, F., Tauran, G., Taylor, M. B., Teixeira, R., Thuillot, W., Tonello, N., Torra, F., Torra, J., Turon, C., Unger, N., Vaillant, M., van Dillen, E., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, L., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., Zurbach, C., and Zwitter, T.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract: We produce a clean and well-characterised catalogue of objects within 100\,pc of the Sun from the \G\ Early Data Release 3. We characterise the catalogue through comparisons to the full data release, external catalogues, and simulations. We carry out a first analysis of the science that is possible with this sample to demonstrate its potential and best practices for its use. The selection of objects within 100\,pc from the full catalogue used selected training sets, machine-learning procedures, astrometric quantities, and solution quality indicators to determine a probability that the astrometric solution is reliable. The training set construction exploited the astrometric data, quality flags, and external photometry. For all candidates we calculated distance posterior probability densities using Bayesian procedures and mock catalogues to define priors. Any object with reliable astrometry and a non-zero probability of being within 100\,pc is included in the catalogue. We have produced a catalogue of \NFINAL\ objects that we estimate contains at least 92\% of stars of stellar type M9 within 100\,pc of the Sun. We estimate that 9\% of the stars in this catalogue probably lie outside 100\,pc, but when the distance probability function is used, a correct treatment of this contamination is possible. We produced luminosity functions with a high signal-to-noise ratio for the main-sequence stars, giants, and white dwarfs. We examined in detail the Hyades cluster, the white dwarf population, and wide-binary systems and produced candidate lists for all three samples. We detected local manifestations of several streams, superclusters, and halo objects, in which we identified 12 members of \G\ Enceladus. We present the first direct parallaxes of five objects in multiple systems within 10\,pc of the Sun., Comment: 45 Pages, 39 figures in main part and 18 in appendix, tables on CDS
Published: 2020
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39. Gaia Early Data Release 3: Acceleration of the solar system from Gaia astrometry

Author: Gaia Collaboration, Klioner, S. A., Mignard, F., Lindegren, L., Bastian, U., McMillan, P. J., Hernández, J., Hobbs, D., Ramos-Lerate, M., Biermann, M., Bombrun, A., de Torres, A., Gerlach, E., Geyer, R., Hilger, T., Lammers, U., Steidelmüller, H., Stephenson, C. A., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Babusiaux, C., Creevey, O. L., Evans, D. W., Eyer, L., Hutton, A., Jansen, F., Jordi, C., Luri, X., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Walton, N. A., Arenou, F., Bailer-Jones, C. A. L., Cropper, M., Drimmel, R., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Castañeda, J., De Angeli, F., Ducourant, C., Fabricius, C., Fouesneau, M., Frémat, Y., Guerra, R., Guerrier, A., Guiraud, J., Piccolo, A. Jean-Antoine, Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Tanga, P., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Brugaletta, E., Burgess, P. W., Busso, G., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., Delchambre, L., Dell'Oro, A., Fernández-Hernández, J., Galluccio, L., García-Lario, P., Garcia-Reinaldos, M., González-Núñez, J., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Heiter, U., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Manteiga, M., Marchal, O., Marrese, P. M., Moitinho, A., Mora, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Richards, P. J., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Ulla, A., Utrilla, E., van Leeuwen, M., van Reeven, W., Abbas, U., Aramburu, A. Abreu, Accart, S., Aerts, C., Aguado, J. J., Ajaj, M., Altavilla, G., Álvarez, M. A., Cid-Fuentes, J. Álvarez, Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Audard, M., Baines, D., Baker, S. G., Balaguer-Nú\-nez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Baudesson-Stella, A., Becciani, U., Bellazzini, M., Bernet, M., Bertone, S., Bianchi, L., Blanco-Cuaresma, S., Boch, T., Bossini, D., Bouquillon, S., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Bucciarelli, B., Burlacu, A., Busonero, D., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cánovas, H., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I, Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Sampol, P. Castro, Chaoul, L., Charlot, P., Chemin, L., Chiavassa, A., Comoretto, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Teodoro, P., del Peloso, E. F., del Pozo, E., Delgado, A., Delgado, H. E., Delisle, J. -B., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Eappachen, D., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Figueras, F., Fouron, C., Fragkoudi, F., Fraile, E., Franke, F., Gai, M., Garabato, D., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gavras, P., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomez, A., Gonzalez-Santamaria, I., González-Vidal, J. J., Granvik, M., Gutiérrez-Sánchez, R., Guy, L. P., Hauser, M., Haywood, M., Helmi, A., Hidalgo, S. L., Hładczuk, N., Holland, G., Huckle, H. E., Jasniewicz, G., Jonker, P. G., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kochoska, A., Kordopatis, G., Korn, A. J., Kostrzewa-Rutkowska, Z., Kruszyńska, K., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Fustec, Y. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Pardo, P. Madrero, Managau, S., Mann, R. G., Marchant, J. M., Marconi, M., Santos, M. M. S. Marcos, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Montegriffo, P., Mor, R., Morbidelli, R., Morel, T., Morris, D., Mulone, A. F., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Noval, L., Ordénovic, C., Orrù, G., Osinde, J., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Panahi, A., Pawlak, M., Esteller, X. Pe\-nalosa, Penttilä, A., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Poretti, E., Poujoulet, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos, P., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rixon, G., Robichon, N., Robin, C., Roelens, M., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Sellés, A. Sagristà, Sahlmann, J., Salgado, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Siddiqui, H. I., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spoto, F., Steele, I. A., Süveges, M., Szabados, L., Szegedi-Elek, E., Taris, F., Tauran, G., Taylor, M. B., Teixeira, R., Thuillot, W., Tonello, N., Torra, F., Torray, J., Turon, C., Unger, N., Vaillant, M., van Dillen, E., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., Zurbach, C., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: Context. Gaia Early Data Release 3 (Gaia EDR3) provides accurate astrometry for about 1.6 million compact (QSO-like) extragalactic sources, 1.2 million of which have the best-quality five-parameter astrometric solutions. Aims. The proper motions of QSO-like sources are used to reveal a systematic pattern due to the acceleration of the solar system barycentre with respect to the rest frame of the Universe. Apart from being an important scientific result by itself, the acceleration measured in this way is a good quality indicator of the Gaia astrometric solution. Methods. The effect of the acceleration is obtained as a part of the general expansion of the vector field of proper motions in Vector Spherical Harmonics (VSH). Various versions of the VSH fit and various subsets of the sources are tried and compared to get the most consistent result and a realistic estimate of its uncertainty. Additional tests with the Gaia astrometric solution are used to get a better idea on possible systematic errors in the estimate. Results. Our best estimate of the acceleration based on Gaia EDR3 is $(2.32 \pm 0.16) \times 10^{-10}$ m s${}^{-2}$ (or $7.33 \pm 0.51$ km s$^{-1}$ Myr${}^{-1}$) towards $\alpha = 269.1^\circ \pm 5.4^\circ$, $\delta = -31.6^\circ \pm 4.1^\circ$, corresponding to a proper motion amplitude of $5.05 \pm 0.35$ $\mu$as yr${}^{-1}$. This is in good agreement with the acceleration expected from current models of the Galactic gravitational potential. We expect that future Gaia data releases will provide estimates of the acceleration with uncertainties substantially below 0.1 $\mu$as yr${}^{-1}$., Comment: A&A, accepted
Published: 2020
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40. Gaia Early Data Release 3: Structure and properties of the Magellanic Clouds

Author: Gaia Collaboration, Luri, X., Chemin, L., Clementini, G., Delgado, H. E., McMillan, P. J., Romero-Gómez, M., Balbinot, E., Castro-Ginard, A., Mor, R., Ripepi, V., Sarro, L. M., Cioni, M. -R. L., Fabricius, C., Garofalo, A., Helmi, A., Muraveva, T., Brown, A. G. A., Vallenari, A., Prusti, T., de, J. H. J., Babusiaux, C., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Hutton, A., Jansen, F., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Walton, N. A., Arenou, F., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Castañeda, J., De, F., Ducourant, C., Fouesneau, M., Frémat, Y., Guerra, R., Guerrier, A., Guiraud, J., Jean-Antoine, A., Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Tanga, P., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Brugaletta, E., Burgess, P. W., Busso, G., Carry, B., Cellino, A., Cheek, N., Damerdji, Y., Davidson, M., Delchambre, L., Dell'Oro, A., Fernández-Hernández, J., Galluccio, L., García-Lario, P., Garcia-Reinaldos, M., González-Núñez, J., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Heiter, U., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Manteiga, M., Marchal, O., Marrese, P. M., Moitinho, A., Mora, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Richards, P. J., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Rybizki, J., Siopis, C., Smith, M., Sozzetti, A., Ulla, A., Utrilla, E., van Leeuwen, M., van Reeven, W., Abbas, U., Abreu, A., Accart, S., Aerts, C., Aguado, J. J., Ajaj, M., Altavilla, G., Álvarez, M. A., Cid-Fuentes, J. Álvarez, Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Audard, M., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Baudesson-Stella, A., Becciani, U., Bellazzini, M., Bernet, M., Bertone, S., Bianchi, L., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Bucciarelli, B., Burlacu, A., Busonero, D., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cánovas, H., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I, Carrasco, J. M., Casamiquela, L., Castellani, M., Sampol, P. Castro, Chaoul, L., Charlot, P., Chiavassa, A., Comoretto, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Teodoro, P., de Torres, A., del Peloso, E. F., del Pozo, E., Delgado, A., Delisle, J. -B., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Eappachen, D., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Figueras, F., Fouron, C., Fragkoudi, F., Fraile, E., Franke, F., Gai, M., Garabato, D., Garcia-Gutierrez, A., García-Torres, M., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomez, A., Gonzalez-Santamaria, I., González-Vidal, J. J., Granvik, M., Gutiérrez-Sánchez, R., Guy, L. P., Hauser, M., Haywood, M., Hidalgo, S. L., Hilger, T., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jasniewicz, G., Jonker, P. G., Juaristi, J., Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kochoska, A., Kontizas, M., Kordopatis, G., Korn, A. J., Kostrzewa-Rutkowska, Z., Kruszyńska, K., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Fustec, Y. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Madrero, P., Managau, S., Mann, R. G., Marchant, J. M., Marconi, M., Marcos, M. M. S., Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Montegriffo, P., Morbidelli, R., Morel, T., Morris, D., Mulone, A. F., Munoz, D., Murphy, C. P., Musella, I., Noval, L., Ordénovic, C., Orrù, G., Osinde, J., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Panahi, A., Pawlak, M., Peñalosa, X., Penttilä, A., Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Poretti, E., Poujoulet, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos, P., Ramos-Lerate, M., Re, P., Regibo, S., Reylé, C., Riva, A., Rixon, G., Robichon, N., Robin, C., Roelens, M., Rohrbasser, L., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Sagristà, A., Sahlmann, J., Salgado, J., Salguero, E., Samaras, N., Sanchez, V., Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Siddiqui, H. I., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spoto, F., Steele, I. A., Steidelmüller, H., Stephenson, C. A., Süveges, M., Szabados, L., Szegedi-Elek, E., Taris, F., Tauran, G., Taylor, M. B., Teixeira, R., Thuillot, W., Tonello, N., Torra, F., Torra, J., Turon, C., Unger, N., Vaillant, M., van, E., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., Zurbach, C., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We compare the Gaia DR2 and Gaia EDR3 performances in the study of the Magellanic Clouds and show the clear improvements in precision and accuracy in the new release. We also show that the systematics still present in the data make the determination of the 3D geometry of the LMC a difficult endeavour; this is at the very limit of the usefulness of the Gaia EDR3 astrometry, but it may become feasible with the use of additional external data. We derive radial and tangential velocity maps and global profiles for the LMC for the several subsamples we defined. To our knowledge, this is the first time that the two planar components of the ordered and random motions are derived for multiple stellar evolutionary phases in a galactic disc outside the Milky Way, showing the differences between younger and older phases. We also analyse the spatial structure and motions in the central region, the bar, and the disc, providing new insights into features and kinematics. Finally, we show that the Gaia EDR3 data allows clearly resolving the Magellanic Bridge, and we trace the density and velocity flow of the stars from the SMC towards the LMC not only globally, but also separately for young and evolved populations. This allows us to confirm an evolved population in the Bridge that is slightly shift from the younger population. Additionally, we were able to study the outskirts of both Magellanic Clouds, in which we detected some well-known features and indications of new ones., Comment: This paper is part of the "demonstration papers" released with Gaia EDR3: https://www.cosmos.esa.int/web/gaia/earlydr3
Published: 2020
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41. Gaia Early Data Release 3: Summary of the contents and survey properties

Author: Gaia Collaboration, Brown, A. G. A, Vallenari, A., Prusti, T., de Bruijne, J. H. J., Babusiaux, C., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Hutton, A., Jansen, F., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Panem, C., Pourbaix, D., Randich, S., Sartoretti, P., Soubiran, C., Walton, N. A., Arenou, F., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Lattanzi, M. G., van Leeuwen, F., Bakker, J., Cacciari, C., Castañeda, J., De Angeli, F., Ducourant, C., Fabricius, C., Fouesneau, M., Frémat, Y., Guerra, R., Guerrier, A., Guiraud, J., Piccolo, A. Jean-Antoine, Masana, E., Messineo, R., Mowlavi, N., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Tanga, P., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Andrae, R., Bellas-Velidis, I., Benson, K., Berthier, J., Blomme, R., Brugaletta, E., Burgess, P. W., Busso, G., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., Delchambre, L., Dell'Oro, A., Fernández-Hernández, J., Galluccio, L., García-Lario, P., Garcia-Reinaldos, M., González-Núñez, J., Gosset, E., Haigron, R., Halbwachs, J. -L., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Heiter, U., Hernández, J., Hestroffer, D., Hodgkin, S. T., Holl, B., Janßen, K., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., o}ffler, W. L\"{, Lorca, A., Manteiga, M., Marchal, O., Marrese, P. M., Moitinho, A., Mora, A., Muinonen, K., Osborne, P., Pancino, E., Pauwels, T., Petit, J. -M., Recio-Blanco, A., Richards, P. J., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Rybizki, J., Sarro, L. M., Siopis, C., Smith, M., Sozzetti, A., Ulla, A., Utrilla, E., van Leeuwen, M., van Reeven, W., Abbas, U., Aramburu, A. Abreu, Accart, S., Aerts, C., Aguado, J. J., Ajaj, M., Altavilla, G., Álvarez, M. A., Cid-Fuentes, J. Álvarez, Alves, J., Anderson, R. I., Varela, E. Anglada, Antoja, T., Audard, M., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balbinot, E., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bassilana, J. -L., Bauchet, N., Baudesson-Stella, A., Becciani, U., Bellazzini, M., Bernet, M., Bertone, S., Bianchi, L., Blanco-Cuaresma, S., Boch, T., Bombrun, A., Bossini, D., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Bucciarelli, B., Burlacu, A., Busonero, D., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cánovas, H., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I, Carrasco, J. M., Casamiquela, L., Castellani, M., Castro-Ginard, A., Sampol, P. Castro, Chaoul, L., Charlot, P., Chemin, L., Chiavassa, A., Cioni, M. -R. L., Comoretto, G., Cooper, W. J., Cornez, T., Cowell, S., Crifo, F., Crosta, M., Crowley, C., Dafonte, C., Dapergolas, A., David, M., David, P., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Teodoro, P., de Torres, A., del Peloso, E. F., del Pozo, E., Delbo, M., Delgado, A., Delgado, H. E., Delisle, J. -B., Di Matteo, P., Diakite, S., Diener, C., Distefano, E., Dolding, C., Eappachen, D., Edvardsson, B., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fedorets, G., Fernique, P., Fienga, A., Figueras, F., Fouron, C., Fragkoudi, F., Fraile, E., Franke, F., Gai, M., Garabato, D., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gavras, P., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., Gonzalez-Santamaria, I., González-Vidal, J. J., Granvik, M., Gutiérrez-Sánchez, R., Guy, L. P., Hauser, M., Haywood, M., Helmi, A., Hidalgo, S. L., Hilger, T., Hładczuk, N., Hobbs, D., Holland, G., Huckle, H. E., Jasniewicz, G., Jonker, P. G., Campillo, J. Juaristi, Julbe, F., Karbevska, L., Kervella, P., Khanna, S., Kochoska, A., Kontizas, M., Kordopatis, G., Korn, A. J., Kostrzewa-Rutkowska, Z., Kruszyńska, K., Lambert, S., Lanza, A. F., Lasne, Y., Campion, J. -F. Le, Fustec, Y. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Leclerc, N., Lecoeur-Taibi, I., Liao, S., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Pardo, P. Madrero, Managau, S., Mann, R. G., Marchant, J. M., Marconi, M., Santos, M. M. S. Marcos, Marinoni, S., Marocco, F., Marshall, D. J., Polo, L. Martin, Martín-Fleitas, J. M., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Montegriffo, P., Mor, R., Morbidelli, R., Morel, T., Morris, D., Mulone, A. F., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Noval, L., Ordénovic, C., Orrù, G., Osinde, J., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Panahi, A., Pawlak, M., Esteller, X. Peñalosa, a}, A. Penttil\"{, Piersimoni, A. M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Poretti, E., Poujoulet, E., Prša, A., Pulone, L., Racero, E., Ragaini, S., Rainer, M., Raiteri, C. M., Rambaux, N., Ramos, P., Ramos-Lerate, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rixon, G., Robichon, N., Robin, C., Roelens, M., Rohrbasser, L., Romero-Gómez, M., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Sellés, A. Sagristà, Sahlmann, J., Salgado, J., Salguero, E., Samaras, N., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Schultheis, M., Sciacca, E., Segol, M., Segovia, J. C., Ségransan, D., Semeux, D., Shahaf, S., Siddiqui, H. I., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Solano, E., Solitro, F., Souami, D., Souchay, J., Spagna, A., Spoto, F., Steele, I. A., u}ller, H. Steidelm\"{, Stephenson, C. A., u}veges, M. S\"{, Szabados, L., Szegedi-Elek, E., Taris, F., Tauran, G., Taylor, M. B., Teixeira, R., Thuillot, W., Tonello, N., Torra, F., Torra, J., Turon, C., Unger, N., Vaillant, M., van Dillen, E., Vanel, O., Vecchiato, A., Viala, Y., Vicente, D., Voutsinas, S., Weiler, M., Wevers, T., Wyrzykowski, Ł., Yoldas, A., Yvard, P., Zhao, H., Zorec, J., Zucker, S., Zurbach, C., and Zwitter, T.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We present the early installment of the third Gaia data release, Gaia EDR3, consisting of astrometry and photometry for 1.8 billion sources brighter than magnitude 21, complemented with the list of radial velocities from Gaia DR2. Gaia EDR3 contains celestial positions and the apparent brightness in G for approximately 1.8 billion sources. For 1.5 billion of those sources, parallaxes, proper motions, and the (G_BP-G_RP) colour are also available. The passbands for G, G_BP, and G_RP are provided as part of the release. For ease of use, the 7 million radial velocities from Gaia DR2 are included in this release, after the removal of a small number of spurious values. New radial velocities will appear as part of Gaia DR3. Finally, Gaia EDR3 represents an updated materialisation of the celestial reference frame (CRF) in the optical, the Gaia-CRF3, which is based solely on extragalactic sources. The creation of the source list for Gaia EDR3 includes enhancements that make it more robust with respect to high proper motion stars, and the disturbing effects of spurious and partially resolved sources. The source list is largely the same as that for Gaia DR2, but it does feature new sources and there are some notable changes. The source list will not change for Gaia DR3. Gaia EDR3 represents a significant advance over Gaia DR2, with parallax precisions increased by 30 percent, proper motion precisions increased by a factor of 2, and the systematic errors in the astrometry suppressed by 30--40 percent for the parallaxes and by a factor ~2.5 for the proper motions. The photometry also features increased precision, but above all much better homogeneity across colour, magnitude, and celestial position. A single passband for G, G_BP, and G_RP is valid over the entire magnitude and colour range, with no systematics above the 1 percent level., Comment: Accepted for A&A Special Issue on Gaia EDR3, 21 pages, 2 figures. This version includes the updates in the erratum (https://doi.org/10.1051/0004-6361/202039657e)
Published: 2020
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42. Photocatalyzed CO2 reduction to CO by supramolecular photocatalysts made of Ru(II) photosensitizers and Re(I) catalytic subunits containing preformed CO2TEOA adducts

Author: Santoro, Antonio, Cancelliere, Ambra M., Kamogawa, Kei, Serroni, Scolastica, Puntoriero, Fausto, Tamaki, Yusuke, Campagna, Sebastiano, and Ishitani, Osamu
Published: 2023
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43. Effectiveness of postsurgical rehabilitation following lumbar disc herniation surgery: A systematic review

Author: Yu, Hainan, Cancelliere, Carol, Mior, Silvano, Pereira, Paulo, Nordin, Margareta, Brunton, Ginny, Wong, Jessica J., Shearer, Heather M., Connell, Gaelan, Ead, Lauren, Verville, Leslie, Rezai, Mana, Myrtos, Danny, Wang, Dan, Marchand, Andrée-Anne, Romanelli, Andrew, Germann, Darrin, To, Daphne, Young, James J., Southerst, Danielle, Candelaria, Henry, Hogg-Johnson, Sheilah, and Côté, Pierre
Published: 2024
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44. Clinical relevance of exosome-derived microRNAs in Ovarian Cancer: Looking for new tumor biological fingerprints

Author: Fanale, Daniele, Corsini, Lidia Rita, Bono, Marco, Randazzo, Ugo, Barraco, Nadia, Brando, Chiara, Cancelliere, Daniela, Contino, Silvia, Giurintano, Ambra, Magrin, Luigi, Pedone, Erika, Perez, Alessandro, Piraino, Paola, Pivetti, Alessia, Giovanni, Emilia Di, Russo, Tancredi Didier Bazan, Prestifilippo, Ornella, Gennusa, Vincenzo, Pantuso, Gianni, Russo, Antonio, and Bazan, Viviana
Published: 2024
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45. Management of Adult Unruptured Brain Arteriovenous Malformations: An Updated Network Meta-Analysis

Author: Adam A. Dmytriw, Jerry Ku, Sherief Ghozy, Sahibjot Grewal, Nicole M. Cancelliere, Ahmed Y. Azzam, Robert W. Regenhardt, James D. Rabinov, Christopher J. Stapleton, Krunal Patel, Aman B. Patel, Vitor Mendes Pereira, and Michael Tymianski
Subjects: arteriovenous malformation, a randomized trial of unruptured brain arteriovenous malformations, neurosurgery, Medicine (General), R5-920, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract: The management of unruptured brain arteriovenous malformations (ubAVMs) is a complex challenge to neurovascular practitioners. This meta-analysis aimed to identify the optimal management of ubAVMs comparing conservative management, embolization, radiosurgery, microsurgical resection, and multimodality. The search strategy was developed a priori according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched the Ovid Medline, Embase, Web of Science, and Cochrane Library databases to identify relevant papers. Using R version 4.1.1., a frequentist network meta-analysis was conducted to compare different management modalities for the ubAVMs. Overall, the conservative group had the lowest risk of rupture (P-score=0.77), and the lowest rate of complications was found in the conservative group (P-score=1). Among different interventions, the multimodality group had the highest rupture risk (P-score=0.34), the lowest overall complications (P-score=0.75), the best functional improvement (P-score=0.65), and the lowest overall mortality (P-score=0.8). However, multimodality treatment showed a significantly higher risk of rupture (odds ratio [OR]=2.13; 95% confidence interval [95% CI]=1.18–3.86) and overall complication rate (OR=5.56; 95% CI=3.37–9.15) compared to conservative management; nevertheless, there were no significant differences in overall mortality or functional independence when considered independently. Conservative management is associated with the lowest rupture risk and complication rate overall. A multimodal approach is the best option when considering mortality rates and functional improvement in the context of existing morbidity/symptoms. Microsurgery, embolization, and radiosurgery alone are similar to the natural history in terms of functional improvement and mortality, but have higher complication rates.
Published: 2023
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46. Label-free electrochemical immunosensor as a reliable point-of-care device for the detection of Interleukin-6 in serum samples from patients with psoriasis

Author: Rocco Cancelliere, Terenzio Cosio, Elena Campione, Martina Corvino, Maria Pia D’Amico, Laura Micheli, Emanuela Signori, and Giorgio Contini
Subjects: interleukin-6, sandwich-based immunosensor, biochar, serum samples, psoriasis, point-ofcare, Chemistry, QD1-999
Abstract: Interleukin-6 (IL-6) plays a crucial role in autoimmunity and chronic inflammation. This study aims to develop a low-cost, simple-to-manufacture, and user-friendly label-free electrochemical point-of-care device for the rapid detection of IL-6 in patients with psoriasis. Precisely, a sandwich-based format immunosensor was developed using two primary antibodies (mAb-IL6 clone-5 and clone-7) and screen-printed electrodes modified with an inexpensive recycling electrochemical enhancing material, called biochar. mAb-IL6 clone-5 was used as a covalently immobilized capture bioreceptor on modified electrodes, and mAb-IL6 clone-7 was used to recognize the immunocomplex (Anti-IL6 clone-5 and IL-6) and form the sandwich. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to conduct electrochemical characterization of the layer-by-layer assembly of the immunosensor, while square wave voltammetry (SWV) was used to perform the sensing. The developed immunosensor demonstrated robust analytical performance in buffer solution, with a wide linear range (LR) by varying from 2 to 250 pg/mL, a good limit of detection (LOD) of 0.78 pg/mL and reproducibility (RSD
Published: 2023
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47. Aspiration Versus Stent‐Retriever as First‐Line Endovascular Therapy Technique for Primary Medium and Distal Intracranial Occlusions: A Propensity‐Score Matched Multicenter Analysis

Author: James E. Siegler, Hamza Shaikh, Jane Khalife, Solomon Oak, Linda Zhang, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Tareq Kass‐Hout, Rami Z. Morsi, Jeremy J. Heit, Robert W. Regenhardt, Jose Danilo Bengzon Diestro, Nicole M. Cancelliere, Sherief Ghozy, Ahmad Sweid, Kareem El Naamani, Abdelaziz Amllay, Lukas Meyer, Anne Dusart, Flavio Bellante, Géraud Forestier, Aymeric Rouchaud, Suzana Saleme, Charbel Mounayer, Jens Fiehler, Anna Luisa Kühn, Ajit S. Puri, Christian Dyzmann, Peter T. Kan, Marco Colasurdo, Gaultier Marnat, Jérôme Berge, Xavier Barreau, Igor Sibon, Simona Nedelcu, Nils Henninger, Thomas R. Marotta, Alvin S. Das, Christopher J. Stapleton, James D. Rabinov, Takahiro Ota, Shogo Dofuku, Leonard L.L. Yeo, Benjamin Y.Q. Tan, Juan Carlos Martinez‐Gutierrez, Sergio Salazar‐Marioni, Sunil A. Sheth, Leonardo Renieri, Carolina Capirossi, Ashkan Mowla, Stavropoula I. Tjoumakaris, Pascal Jabbour, Priyank Khandelwal, Arundhati Biswas, Frédéric Clarençon, Mahmoud Elhorany, Kevin Premat, Iacopo Valente, Alessandro Pedicelli, João Pedro Filipe, Ricardo Varela, Miguel Quintero‐Consuegra, Nestor R. Gonzalez, Markus A. Möhlenbruch, Jessica Jesser, Vincent Costalat, Adrien ter Schiphorst, Vivek Yedavalli, Pablo Harker, Lina M. Chervak, Yasmin Aziz, Maria Bres Bullrich, Luciano Sposato, Benjamin Gory, Constantin Hecker, Monika Killer‐Oberpfalzer, Christoph J. Griessenauer, Ajith J. Thomas, Cheng‐Yang Hsieh, David S. Liebeskind, Răzvan Alexandru Radu, Andrea M. Alexandre, Illario Tancredi, Tobias D. Faizy, Robert Fahed, Charlotte Weyland, Aman B. Patel, Vitor Mendes Pereira, Boris Lubicz, Adrien Guenego, and Adam A. Dmytriw
Subjects: outcomes research, stroke, thrombectomy, Neurology. Diseases of the nervous system, RC346-429, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Background For acute proximal intracranial artery occlusions, contact aspiration may be more effective than stent‐retriever for first‐line reperfusion therapy. Due to the lack of data regarding medium vessel occlusion thrombectomy, we evaluated outcomes according to first‐line technique in a large, multicenter registry. Methods Imaging, procedural, and clinical outcomes of patients with acute proximal medium vessel occlusions (M2, A1, or P1) or distal medium vessel occlusions (M3, A2, P2, or further) treated at 37 sites in 10 countries were analyzed according to first‐line endovascular technique (stent‐retriever versus aspiration). Multivariable logistic regression and propensity‐score matching were used to estimate the odds of the primary outcome, expanded Thrombolysis in Cerebral Infarction score of 2b–3 (“successful recanalization”), as well as secondary outcomes (first‐pass effect, expanded Thrombolysis in Cerebral Infarction 2c‐3, intracerebral hemorrhage, and 90‐day modified Rankin scale, 90‐day mortality) between treatment groups. Results Of the 440 included patients (44.5% stent‐retriever versus 55.5% aspiration), those treated with stent‐retriever had lower baseline Alberta Stroke Program Early Computed Tomography Scale scores (median 8 versus 9; P
Published: 2023
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48. Abstract 168: Platelet function testing and risk of periprocedural complications with flow diversion: An international multicenter study

Author: Justin E. Vranic, Adam A. Dmytriw, Inka K. Berglar, Naif M. Alotaibi, Nicole M. Cancelliere, Christopher J. Stapleton, James D. Rabinov, Pablo Harker, Rajiv Gupta, Matthew J. Koch, Scott B. Raymond, Justin R. Mascitelli, T. Masoud Patterson, Kareem El Namaani, Anna L. Kühn, Bryan Pukenas, Brian Jankowitz, Jan M. Burkhardt, Adnan H. Siddiqui, Pascal Jabbour, Jasmeet Singh, Ajit S. Puri, Robert Regenhardt, Vitor M. Pereira, and Aman Patel
Subjects: Neurology. Diseases of the nervous system, RC346-429, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Introduction Dual antiplatelet therapy (DAPT) is necessary to minimize the risk of periprocedural thromboembolic complications associated with aneurysm embolization using Pipeline embolization device (PED). We sought to assess the impact of platelet function testing (PFT) on reducing periprocedural thromboembolic complications associated with PED flow diversion in patients receiving aspirin and clopidogrel. Methods Patients with unruptured intracranial aneurysms requiring PED flow diversion were identified from 13 centers for retrospective evaluation. Clinical variables including the results of PFT prior to treatment, periprocedural DAPT regimen, and intracranial complications occurring within 72‐hours of embolization were identified from the medical record. Complication rates were compared between PFT and non‐PFT groups. Differences between groups were tested for statistical significance using the Wilcoxon rank sum, Fisher exact, or Chi‐square tests. A p‐value 0.9). Conclusion Pre‐procedural PFT prior to PED treatment of intracranial aneurysms in patients pre‐medicated with an aspirin and clopidogrel DAPT regimen may not be necessary to significantly reduce the risk of procedure‐related intracranial complications.
Published: 2023
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49. Copy mechanism and tailored training for character-based data-to-text generation

Author: Roberti, Marco, Bonetta, Giovanni, Cancelliere, Rossella, and Gallinari, Patrick
Subjects: Computer Science - Machine Learning, Computer Science - Computation and Language, Computer Science - Neural and Evolutionary Computing, Statistics - Machine Learning, 68T50
Abstract: In the last few years, many different methods have been focusing on using deep recurrent neural networks for natural language generation. The most widely used sequence-to-sequence neural methods are word-based: as such, they need a pre-processing step called delexicalization (conversely, relexicalization) to deal with uncommon or unknown words. These forms of processing, however, give rise to models that depend on the vocabulary used and are not completely neural. In this work, we present an end-to-end sequence-to-sequence model with attention mechanism which reads and generates at a character level, no longer requiring delexicalization, tokenization, nor even lowercasing. Moreover, since characters constitute the common "building blocks" of every text, it also allows a more general approach to text generation, enabling the possibility to exploit transfer learning for training. These skills are obtained thanks to two major features: (i) the possibility to alternate between the standard generation mechanism and a copy one, which allows to directly copy input facts to produce outputs, and (ii) the use of an original training pipeline that further improves the quality of the generated texts. We also introduce a new dataset called E2E+, designed to highlight the copying capabilities of character-based models, that is a modified version of the well-known E2E dataset used in the E2E Challenge. We tested our model according to five broadly accepted metrics (including the widely used BLEU), showing that it yields competitive performance with respect to both character-based and word-based approaches., Comment: ECML-PKDD 2019 (Camera ready version)
Published: 2019
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50. Regularization-based pruning of irrelevant weights in deep neural architectures

Author: Bonetta, Giovanni, Ribero, Matteo, and Cancelliere, Rossella
Published: 2023
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