1. T cells engineered to home in on brain cancer
- Author
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Platten, Michael
- Subjects
Brain cancer -- Research -- Care and treatment ,T cells -- Research ,Tissue engineering -- Research ,Tumors ,Endothelium ,Encephalitis ,Cancer ,Immunotherapy ,Environmental issues ,Science and technology ,Zoology and wildlife conservation - Abstract
Immunotherapies activate T cells to destroy tumours, but the approach has failed in some brain cancers. A strategy to improve migration of T cells across the blood-brain barrier could overcome this limitation.A synthetic ligand enhances T-cell binding to brain endothelial cells., Author(s): Michael PlattenAuthor Affiliations:T cells engineered to home in on brain cancer In the disease encephalitis, brain inflammation occurs because T cells that are typically excluded from the brain migrate [...]
- Published
- 2018
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