T cells engineered to home in on brain cancer

Immunotherapies activate T cells to destroy tumours, but the approach has failed in some brain cancers. A strategy to improve migration of T cells across the blood-brain barrier could overcome this limitation.A synthetic ligand enhances T-cell binding to brain endothelial cells.
Author(s): Michael PlattenAuthor Affiliations:T cells engineered to home in on brain cancer In the disease encephalitis, brain inflammation occurs because T cells that are typically excluded from the brain migrate [...]