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4. Molecular Biology of Tf

Author

Edgington, Thomas S., Ruf, Wolfram, Goldstein, Allan L., editor, Kumar, Ajit, editor, Bailey, J. Martyn, editor, and Gallo, Linda L., editor

Published
1995
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18. Abstracts of papers and posters

Author

Anthonio, R. L., Willemsen, A. T. M., Visser, T., van Waarde, A., Elzinga, P., Weemaes, A., Meeder, J. G., Pruim, J., Visser, G., Blanksma, P. K., Vaalburg, W., Bloemen, P. G. M., Henricks, P. A. J., van Bloois, L., van den Tweel, M. C., Nijkamp, F. P., Crommelin, D. J. A., Storm, G., de Boer, A. H., Winter, H. M. I., Lerk, C. F., de Boer, J., Meurs, H., Bottone, A. E., Koopal, M., Visser, J. C., Zaagsma, J., Borger P., Kauffman H. F., Vijgen J. L. J., Postma D. S., Vellenga E., Buckley, Theresa L., Buikema, H., van Gilst, W. H., van Veldhuisen, D. J., de Smet, B. J. G. L., Scholtens, E., Lie, K. I., Wesseling, H., Cheung, P. K., Dijkhuis, F. W. D., Bakker, W. W., Visser, J., Coopes, R. P., Benthem, L., van der Leest, J., Roffel, A. F., Coppes, R. P., Zeilstra, L. J. W., Vissink, A., Konings, A. W. T., Dijkstra, M., Veld, G. In't, Müller, M., van den Berg, G. J., Kuipers, F., Vonk, R. J., Elsinga, P. H., Franssen, E. J. F., van der Graaf, W. T. A., de Vries, E. G. E., Visser, G. M., Vos, M. G., Braker, A. H., Visser, T. J., Visser, G. M., Engels, F., van Houwelingen, A. H., van de Velde, M. J., Gansevoort, R. T., Sluiter, W. J., Hemmelder, M. H., de Zeeuw, D., de Jong, P. E., Gelissen, H. P. M. M., Henning, R. H., Epema, A. H., van Eekeren, J., Hennis, P. J., Den Hertog, A., de Graaf, S. S. N., Kellie, S. J., Bloemhof, H., Johnston, I., Besser, M., Chaseling, R. W., Ouvrier, R. A., Uqes, D. R. A., De Haan, A., Geerligs, H. J., Huchshorn, J. P., Van Scharenburg, G. J. M., Wilschut, J., Haas, M., Kluppel, C. A., Meijer, D. K. F., Moolenaar, F., Heerdink, Eibert R., Leufkens, Hubert G., Herings, Ron M. C., Stricker, Bruno H. Ch., Bakker, Albert, Heesen W. F., Beltman F. W., Smit A. J., May J. F., Meyboom-de Jong B., Duin, M., van den Akker, J., te Pas, M. F. W., van Popta, J. P., Nelemans, S. A., van der Linde, H. J., de Boer, A., Sturmans, F., Hessel, E. M., Van Oosterhout, A. J. M., Hofstra, C. L., Garssen, J., van Loveren, H., Savelkoul, H. F. J., Hoekstra, Y., Weersink, E. J. M., de Jong, J. W., van der Belt-Gritter, B., Jonkman, Lisa M., Kemner, Chantal, Koelega, Harry S., van Engeland, Herman, Verbaten, Marinus N., Kalivianakis, M., Zijlstra, I., Verkade, H. J., Elzinga, H., Stellaard, F., Kamps, J. A. A. M., Swart, P. J., Morselt, H., Scherphof, G. L., Kenemans, J. L., Lorist, M. M., Koopen, N. R., Kraneveld, A. D., Koster, A. Si., Kuipers, M. E., Groenink, M., Huisman, H., Schuitemaker, H., Lau, H. S., van den Broek, I. J. P. M., van Dijk, A., Oostinga, J., Porsius, A. J., Lin, Y., Havinga, R., Meijer, R. J., van der Mark, Th. W., Koëter, G. H., Michels, A. A., Nguyen, V. -T., Bensaude, O., Kampinga, H. H., Mohede, Inge C. M., Van Antoon J. M., Molema, Grietje, Edgington, Thomas S., Thorpe, Philip E., Olinga, P., Sandker, G. W., Slooff, M. J. H., Merema, M. T., Groothuis, G. M. M., Hofman, G., Van Ark, I., Paulussen, J. J. C., Fischer, M. J. E., de Mol, N. J., Janssen, L. H. M., Peters, E. Th. J., van der Werf, G. Th., Haaijer-Ruskamp, F. M., Pinto, Yigal M., Rooks, Gerrit, Grandjean, Jean G., Ebels, Tjark, Schunkert, H., Redegeld, Frank A., Garssen, Johan, van Loveren, Henk, Rigter, Irma M., van Groningen, Muck, Boks, Gertjan J., Tollenaere, Jan P., Trollope, Keith I., Vinter, Jeremy G., Hashjin, Gudarz Sadeghi, Folkerts, Gert, van de Loo, Peet G. F., Santing, R. E., Olymulder, C. G., van der Molen, K., Pasman, Y., Scheerens, Heleen, Van Loveren, Henk, Seppenwoolde-Waasdorp, T. J. A., de Boer, P., Van Engelen, H. M. J., Thijssen, J. H. H., Maes, R. A. A., Smit, J., Smit, J. W., Steen, H., Steurs, M. H., Kuks, P. F. M., Leusink, J. A., Szabó, Balázs M., Crijns, Harry J. G. M., Wiesfeld, Ans C. P., Talsma, H., Borchert, J. C. H., van Steenbergen, M. J., Hennink, W. E., Teeuw, K. B., Cromheecke, H., Schreudering, A., Teisman, B. C. H., Maselbas, W., Wolters-Keulemans, G. T. P., Tieleman, R. G., de Langen, C. D. J., Bel, K., Crijns, H. J. G. M., Grandjean, J., Wijffels, M., Klimp, A. H., van de Meer, P. F., Allessie, M. A., van Patot, H. A. Tissot, de Jongh, B. M., Tuininga, Y. S., Brouwer, J., Haaksma, J., Man in't Veld, A. J., Blomjous, F. J., Vingerhoeds, M. H., Belliot, S. O., Haisma, H. J., Visscher, C. A., Huisman, R. M., Navis, G. J., de Vlieger, J. F., van den Wijngaard, P., Wilting, J., van Heuven-Nolsen, D., Voors, A. A., van Brussel, B. L., Plokker, H. W. M., Van Waardenburg R. C. A. M., Meijer, Prins J., De Vries, C., Mulder N. H., Wierenga, P. K., Wilschut J., Schoen P., and Bron R.

Published
1994
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20. Energetic contributions and topographical organization of ligand binding residues of tissue factor

Author

Ruf, Wolfram, Kelly, Curtis R., Schullek, John R., Martin, David M.A., Polikarpov, Igor, Boys, C. William G., Tuddenham, Edward G.D., and Edgington, Thomas S.

Subjects
Ligand binding (Biochemistry) -- Research, Biological sciences, Chemistry
Abstract

The cell surface receptor tissue factor (TF) binds to the serine protease coagulation factor VIIa. The binding sites are present from TF's concave side of the elbow angle at the module boundary to the convex side of the amino-terminal module at the edge of the three- and four-stranded beta-sheet. These ligand binding sites contribute one-third of the energy required for binding, while additional energy is contributed by the residues on the convex surface of the amino-terminal module.

Published
1995

22. Mutational mapping of functional residues in tissue factor: identification of factor VII recognition determinants in both structural modules of the predicted cytokine receptor homology domain

Author

Ruf, Wolfram, Schullek, John R., Stone, Martin J., and Edgington, Thomas S.

Subjects
Mutation (Biology) -- Research, Cytokines -- Research, Alanine -- Analysis, Biological sciences, Chemistry
Abstract

A study of residue side chains reveals that the tissue factor extracellular domain possibly adopts the cytokine receptor homology unit folding pattern with two seven-beta-strand modules. Mutational analysis suggests that important residues are spatially closer and present as a cluster on the beta-strand module boundary. Residues involved in ligand binding occur in positions corresponding to ligand interactive residues.

Published
1994

31. Transmission of Type B Viral Hepatitis to Chimpanzees

Author

Barker, Lewellys F., Chisari, Francis V., McGrath, Philip P., Dalgard, Dan W., Kirschstein, Ruth L., Almeida, June D., Edgington, Thomas S., Sharp, D. Gordon, and Peterson, Michael R.

Published
1973

33. Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor

Author

Huang, Haining, Norledge, Brian V., Liu, Cheng, Olson, Arthur J., and Edgington, Thomas S.

Subjects
Thrombosis -- Physiological aspects, Blood clot -- Physiological aspects, Protein binding -- Physiological aspects, Protein binding -- Analysis, Proteases -- Physiological aspects, Cell receptors -- Physiological aspects, Biological sciences, Chemistry
Abstract

A combinatorial library derived peptide, which binds to the extracellular domain of tissue factor, exhibits selective and quantitatively limited attenuation of factor X and the extrinsic limb of the coagulation protease cascades. Data indicate that such peptides provide attenuation of thrombotic risk on a long-term basis.

Published
2003

36. LIST OF CONTRIBUTORS

Author

ABELL, C.W., primary, ALFORD, ROBERT H., additional, ALTER, B.J., additional, ANDERSON, A.O., additional, ANDERSON, DEBORAH J., additional, ANDERSON, SUSAN M., additional, ANDRON, L.A., additional, ANTON, ELIZABETH, additional, ARALA-CHAVES, M.P., additional, ARNON, R., additional, ASCHER, M.S., additional, BACH, F.H., additional, BAIRD, LYNN G., additional, BARCINSKI, MARCELLO A., additional, BARKER, BARBARA E., additional, BARTH, ROLF F., additional, BATTISTO, JACK R., additional, BELL, CLARA, additional, BEN-SASSON, SHMUEL A., additional, BERKE, GIDEON, additional, BERNHEIM, JAN L., additional, BESSLER, WOLFGANG G., additional, BETEL, IDO, additional, BETZ, SALLY J., additional, BEYER, C.F., additional, BLAESE, R. MICHAEL, additional, BLANKWATER, M.J., additional, BOCHERT, G., additional, BOCKMAN, D.E., additional, BOLDT, DAVID H., additional, BONA, CONSTANTIN, additional, BONAVIDA, BENJAMIN, additional, BONNARD, GUY D., additional, BOREL, J.F., additional, BOWERS, W.E., additional, BRAATZ, J.A., additional, BRADLEY, B., additional, BRADLEY, B.A., additional, BRAUNSTEINER, HERBERT, additional, BRODER, S., additional, BROWN, JOHN M., additional, BUNDY, BONITA M., additional, BURGER, D.R., additional, CAMBELL, D.A., additional, CARPENTER, C.B., additional, CASTAGNOLA, JAN, additional, CAVILES, ALENDRY P., additional, CHAKRAVARTY, A.K., additional, CHAPLIN, D.D., additional, CHARMOT, D., additional, CHISARI, F.V., additional, CLARK, W.R., additional, CLEMENTS, PHILIP J., additional, COHEN, I.R., additional, COOPER, HERBERT L., additional, COOPER, M.D., additional, COOPER, R.A., additional, CORLEY, RONALD B., additional, CROSIER, P., additional, CUNNINGHAM-RUNDLES, S., additional, CURTISS, LINDA K., additional, DANIELE, RONALD P., additional, DARAI, G., additional, DAUSSET, J., additional, DAVID, JOHN R., additional, DAYNES, RAYMOND A., additional, DEAN, JACK H., additional, DEBATES, MARY JO, additional, DECKER, JEAN M., additional, DE GOEDE, R.E.Y, additional, DEHEER, DAVID H., additional, DELFRAISSY, J.F., additional, DEWOLF, W.C., additional, DOOLEY, N.D., additional, DOOLEY, NANCY J., additional, DORIAN, RANDEL, additional, DORMONT, J., additional, DOUGLAS, GARY N., additional, DRAY, SHELDON, additional, DUPONT, B., additional, DURM, M., additional, DWYER, JOHN M., additional, EDGINGTON, THOMAS S., additional, ELFERINK, DIENNE, additional, ENDRES, ROBERT O., additional, ESSELMAN, WALTER J., additional, FAGAN, G., additional, FARNES, PATRICIA, additional, FAUCI, ANTHONY S., additional, FERGUSON, RONALD M., additional, FERRARINI, M., additional, FLETCHER, MARK P., additional, FRELINGER, JEFFREY A., additional, FORSDYKE, D.R., additional, FROST, A.F., additional, FUDENBERG, H. HUGH, additional, GALANAUD, P., additional, GAROVOY, M.R., additional, GARRIDO, F., additional, GEHA, RAIF S., additional, GEMSA, DIETHARD, additional, GEORGE, K., additional, GERSHWIN, M. ERIC, additional, GLICKMAN, E., additional, GOLDBLUM, R.M., additional, GOLDMAN, C., additional, GOLDSTEIN, ALLAN L., additional, GOOD, R.A., additional, GORDON, DAVID S., additional, GORDON, G., additional, GORDON, IAN L., additional, GORDON, JULIUS, additional, GORENBERG, DAVID J., additional, GORSKA, R., additional, GORSKI, A.J., additional, GOTTLIEB, M.N., additional, GRANBERG, CHRISTER, additional, GRANGER, GALE A., additional, GRAYBILL, J. RICHARD, additional, GREY, HOWARD M., additional, GRILLOT-COURVALIN, C., additional, GRIMM, ELIZABETH ANN, additional, GRINWICH, KAZIMIERA, additional, GROSSI, C.E., additional, GüNTHER, EBERHARD, additional, GUERRY, D., additional, HAMILL, BARBARA, additional, HANSEN, J.A., additional, HANTKE, KLAUS, additional, HAYWARD, A.R., additional, HEININGER, D., additional, HELDERMAN, J. HAROLD, additional, HENKART, PIERRE A., additional, HENNEY, CHRISTOPHER H., additional, HERBERMAN, R.B., additional, HESTER, RAYMOND B., additional, HIRSCHBERG, HENRY, additional, HISERODT, JOHN C., additional, HOETTE, M., additional, HOLIMAN, B.J., additional, HORSMANHEIMO, A., additional, HORSMANHEIMO, M., additional, SUNY, MICHAEL L. HOWE, additional, HUBER, CHRISTOPH, additional, HURTUBISE, P.E., additional, IKEDA, RICHARD, additional, ITZCHAKI, M., additional, JACOBS, DIANE M., additional, JANICKI, BERNARD W., additional, JARRETT-TOTH, E., additional, JENSEN, PAMELA, additional, JERRY, L. MARTIN, additional, JONES, THOMAS B., additional, JONGENEEL, C. VICTOR, additional, JUNGFER, H., additional, KACENA, AMELIA, additional, KALDANY, A., additional, KAPLAN, ALAN M., additional, KAPLAN, J.G., additional, KASHKET, EVA R., additional, KAY, H. DAVID, additional, KAZURA, J., additional, KEARNEY, J.K., additional, KERMANI-ARAB, V., additional, KIERSZENBAUM, F., additional, KEYSSNER, K., additional, KIRCHNER, H., additional, KIRKPATRICK, CHARLES H., additional, KLEIN, J., additional, KLIMPEL, GARY, additional, KOLB, W.P., additional, KORN, J., additional, KOSKI, L.J., additional, KRAKAUER, R., additional, KRUISBEEK, ADA M., additional, KRUITHOF, E.K.O., additional, KUBO, RALPH T., additional, LANOTTE, M., additional, LAUGHTER, ARLINE H., additional, LAUGHTER, BARBARA J., additional, LA VIA, D.S., additional, LA VIA, M.F., additional, LAWRENCE, E.C., additional, LAWTON, A.R., additional, LEGRAND, L., additional, LEON, MYRON A., additional, LESLIE, G.A., additional, UCLA, JOSHUA LEVY, additional, LICHTMAN, M.A., additional, LIFTON, J., additional, LIGHTBODY, JAMES J., additional, LINKER-ISRAELI, M., additional, LOPATIN, DENNIS E., additional, LORARCHER, ALOIS, additional, LORD, EDITH M., additional, LUCAS, DAVID O., additional, LUCAS, KEES, additional, LUNDIN, A.P., additional, LYDYARD, P.M., additional, MCCALMON, ROBERT T., additional, MACDERMOTT, RICHARD P., additional, MCDOUGAL, J.S., additional, MCINTIRE, K.R., additional, MACKLER, BRUCE F., additional, MADYASTHA, K.R., additional, MADYASTHA, P.R., additional, MÄHLER, BERND, additional, MAKI, TAKASHI, additional, MANNINEN, KIMMO, additional, MARTIJNSE, JOKE, additional, MAWAS, C., additional, MAYER, EUGENE P., additional, MEADE, B., additional, MENDELSOHN, JOHN, additional, MENZEL, J., additional, MERGENHAGEN, S.E., additional, METZGER, JOACHIM, additional, MILLER, GINGER W., additional, MILLER, HAROLD C., additional, MILLER, J., additional, MILLS, G., additional, MINGARI, M.C., additional, MOERMAN, C., additional, MOLDOW, C.F., additional, MONAHAN, T.M., additional, MORETTA, A., additional, MORETTA, L., additional, MORRISON, DAVID C., additional, MOTICKA, EDWARD J., additional, MUCHMORE, ANDREW V., additional, MULLER-EBERHARD, H.J., additional, MUNK, K., additional, MUUL, L., additional, NASH, GEOFFREY S., additional, NEGENDANK, W., additional, NELSON, DAVID L., additional, NELSON, J.A., additional, NETA, R., additional, NEWELL, LAURIE, additional, NG, A.K., additional, O'BRIEN, RICHARD L., additional, OEHLER, J.R., additional, O'NEILL, PEGGY A., additional, OPPENHEIM, JOOST J., additional, ORTALDO, J.R., additional, PAHWA, S., additional, PANIJEL, J., additional, PAPE, GERD R., additional, PARADYSZ, J., additional, PARKER, C.W., additional, PARKER, JOHN W., additional, PARRILLO, JOSEPH E., additional, PAWELEC, G.P., additional, PEARSON, CARL M., additional, PERLMANN, PETER, additional, PILARSKI, LINDA M., additional, PLATA, FERNANDO, additional, PLESCIA, ANNE M., additional, PLESCIA, OTTO J., additional, PONZIO, N.M., additional, POPLACK, D.G., additional, PRATT, KAREN R., additional, PUNTIS, M.C.A, additional, RANNEY, DAVID F., additional, RASMUSSEN, HOWARD, additional, REDELMAN, DOUG, additional, RESCH, KLAUS, additional, RICH, ROBERT R., additional, RICH, SUSAN SOLLIDAY, additional, ROBERTS, R.L., additional, RODE, HAROLD N., additional, ROSENSTREICH, DAVID L., additional, ROSENTHAL, ALAN S., additional, ROSSIO, JEFFREY L., additional, ROWDEN, GEOFFREY, additional, ROWLAND, GEORGE, additional, RUBIN, ARNOLD S., additional, RüDE, ERWIN, additional, RüHL, H., additional, RüHL, U., additional, RYAN, JOHN L., additional, SALVIN, S.B., additional, SASPORTES, M., additional, SCHIRRMACHER, V., additional, SCHMALSTIEG, F.C., additional, SCHMIDTKE, JON R., additional, SCHOLLE, H., additional, SCHRIEBER, A.D., additional, SCHUBERT, RICHARD D., additional, SEGEL, G.B., additional, SELL, STEWART, additional, SHALLER, C., additional, SHARON, N., additional, SHEA, MARY, additional, SHEEHAN, JAMES M., additional, SHEPPARD, HAYNES W., additional, SHEPPARD, J.R., additional, SHERIDAN, JOHN, additional, SHEVACH, ETHAN M., additional, SHIFRINE, M., additional, SHIFTAN, THOMAS A., additional, SHORE, STEVEN L., additional, SIMMONS, RICHARD L., additional, SMITH, ALAN, additional, SMITH, TERRILL K., additional, SOULILLOU, J.P., additional, SPECKART, STEPHEN F., additional, SPELLMAN, CRAIG W., additional, STEGGEMANN, LUDWIG, additional, STEINMAN, L., additional, STEJSKAL, VERA, additional, STEWART, CARLETON C., additional, STITES, DANIEL P., additional, ST. LOUIS, G., additional, STOBO, J.D., additional, STOECK, MICHAEL, additional, STRAUSS, PHYLLIS R., additional, STROBER, W., additional, STROM, TERRY B., additional, SULLIVAN, ARTHUR K., additional, SUNDSMO, J.S., additional, SUTCLIFFE, MARILYN C., additional, SUTHANTHIRAN, M., additional, SWART, A.C.W., additional, TAYLOR, CLIVE R., additional, TEITELBAUM, D., additional, TEODORESCU, MARIUS, additional, TERMIJTELEN, A., additional, THESTRUP-PEDERSEN, KRISTIAN, additional, LE THI, HIEN, additional, THOMAS, DAVID W., additional, THORBECKE, G.J., additional, THORSBY, ERIK, additional, THURMAN, GARY B., additional, TILL, GERD, additional, TILNEY, N.L., additional, TOIVANEN, PAAVO, additional, TOMASI, THOMAS B., additional, TOUTON, M., additional, TRAININ, N., additional, TREFTS, PARK E., additional, TROWBRIDGE, SIDNEYE, additional, TRUFFA-BACHI, PAULO, additional, UBELS-POSTMA, JOSÉ, additional, UMIEL, T., additional, VAN BEKKUM, D.W., additional, VAN DE BERG, TINEKE, additional, VAN DEN TWEEL, JAN G., additional, VAN DEN WESTEN, GERARD, additional, VAN HEES, MARITA, additional, VAN OERS, M.H.J., additional, VAN ROOD, J.J., additional, VOGT, W., additional, WAKSMAN, B.H., additional, WALDMANN, T.A., additional, WALKER, WILLIAM S., additional, WALLON, CH., additional, WARE, CARL F., additional, WEBB, S.R., additional, WEBER, W.T., additional, WEDNER, H.J., additional, WERNET, P., additional, WEST, WILLIAM H., additional, WHISLER, R.L., additional, WIESINGER, DOROTHEE, additional, WIGZELL, HANS, additional, WILCOX, C., additional, WILSON, F.D., additional, WINKELSTEIN, A., additional, WOOD, DAVID D., additional, WOODWARD, JEROLD G., additional, WRIGHT, S.C., additional, YEN, BELINDA, additional, YOSHIDA, TAKESHI, additional, YU, DAVID TAK YAN, additional, ZEIJLEMAKER, W.P., additional, ZICCA, A., additional, ZIER, KAREN, additional, and ZIMMERMANN, RITA, additional

Published
1977
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