1. The efficacy and safety of balloon dilation for unresectable malignant biliary obstruction before placement of self‐expanding metal stents.
- Author
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Shen, Zhen Yang, Wang, Jun Jun, Lu, Lun Gen, Wan, Rong, Wan, Xin Jian, and Cai, Xiao Bo
- Subjects
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ENDOSCOPIC retrograde cholangiopancreatography , *BLOOD serum analysis , *MEDICAL balloons , *CATHETERIZATION , *METALS - Abstract
Objective: To evaluate whether patients with malignant biliary obstruction (MBO) benefit from balloon dilation before the placement of a self‐expanding metal stent (SEMS) for palliative biliary drainage. Methods: Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with SEMS placement for palliative management of MBO were retrospectively included. Comparative analyses of serum bilirubin levels, post‐procedural adverse events, stent patency time, stent dysfunction, and patient survival were performed between the dilation and non‐dilation groups. Results: A total of 221 patients underwent palliative endoscopic SEMS implantation for MBO from January 2014 to June 2018. Dilation significantly improved the percentage of serum bilirubin improvement (37.0% vs 14.3%, P = 0.001), with a decreasing trend in the incidence of post‐procedural cholangitis (2.5% vs 7.8%, P = 0.075), while the rates of other complications such as pancreatitis and bleeding were not increased. The patency time of SEMS and patient survival did not significantly differ between patients with and without dilation. Patients had endoscopic nasobiliary drainage (ENBD) but not dilation showed similar short‐term outcomes as patients underwent dilation but without ENBD. Conclusions: Dilation with a small‐caliber balloon catheter before the placement of SEMS is a safe and effective approach for MBO. Balloon dilation may improve the short‐term efficacy of SEMS placement, while long‐term outcomes are not obviously affected. The short‐term effect of stricture dilation may be achieved by ENBD. Further studies are needed to confirm our results. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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