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A graphical abstract of the study "Synthesis of Densely Substituted Dispirocyclopentanebisoxindoles by Base Promoted Sequential Reaction of Two Different 3-Methyleneoxindoles With Thiol" by Guo-Liang Shen and colleagues is presented.

An efficient protocol for the diastereoselective synthesis of the title compounds by 1,3-dipolar cycloaddition of N-phenacylbenzothiazolium and N-phenacylthiazolium bromides with several oxindoles is reported. [ABSTRACT FROM AUTHOR]

Abstract: Triethylamine promoted cycloaddition reaction of N‐alkoxycarbonylmethylquinolinium bromide with isatylidene malononitriles afforded diastereoisomeric spiro[indoline‐3, 2′‐pyrrolo[1, 2‐a]quinolines] in satisfactory yields. The similar 1,3‐dipolar cycloaddition with N‐(p‐nitrobenzyl)quinolinlium bromide gave spiro[indoline‐3, 2′‐pyrrolo[1, 2‐a]quinolines] in good yields and with high diastereoselectivity. More importantly, the sequential cycloaddition reaction and oxidation reaction with 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone (DDQ) resulted in novel 2‐(2‐oxoindolin‐3‐ylidene)‐2‐(2‐(dicyanomethylene)quinolin‐1‐yl)acetates. [ABSTRACT FROM AUTHOR]

An abstract on the domino cycloaddition reactions of N-benzylbenzimidazolium salts with oxoindolin and ylidene acetates is presented.

Some new compounds ( E)-3-aryl-1-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-prop-2-en-1-ones 5a-e were prepared by 1-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-ethanone and various aromatic aldehydes. Then one pot reaction was happened by compounds 5a-e with hydrazine hydrate in acetic acid or propionic acid, respectively, to give the title compounds 1acyl-5-aryl-3-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-4,5-dihydro-1 H-pyrazoles 6a-i. All structures were established by MS, IR, CHN, 1H-NMR and 13C-NMR spectral data. J. Heterocyclic Chem., (2012). [ABSTRACT FROM AUTHOR]

Some new target products 5-aryl-4,5-dihydro-3-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-1-(4-phenylthiazol-2-yl)pyrazoles 5a-j have been synthesized by reaction of 2-bromo-1-phenylethanone and compounds 4a-j which were prepared from the combination of thiosemicarbazide and ( E)-3-aryl-1-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-prop-2-en-1-ones 3a-j. All the structures were established by MS, IR, CHN, and 1H NMR spectra data. Synthesis of structure diversity is applied. J. Heterocyclic Chem., (2011). [ABSTRACT FROM AUTHOR]

Title triazolyldihydropyrazoles (V) are prepared as potential anti-tuberculosis agents. [ABSTRACT FROM AUTHOR]