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Summary. This report presents a historical and descriptive account of randomized trials in childhood leukaemia since the earliest such studies in the 1960s. It focuses on trials that began before 1988, making use of the register of trials developed for a systematic review of treatments for acute lymphoblastic leukaemia in children. The number of randomized trials starting each year increased from one or two in the 1960s to an annual average of five or six in the 1980s. However trials remained relatively small, with more than half of all randomizations accruing less than 200 patients and only five having more than 1000. Most trials were published more than once. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 27-year-old Filipino woman who complained of a three-day history of colicky right-sided abdominal pain. The use of computed tomography (CT) revealed that there is a large, right-sided ileo-colonic intussusception along her mid-transverse colon. She was prepared for laparoscopic surgery after knowing it was adult intussusception. Her case illustrated that rapid CT diagnosis followed by laparoscopic surgery is an effective care for cases of intussusception.

Summary A case of uterine arteriovenous malformation following a dilatation and curettage is presented. Initial diagnosis with colour and pulsed Doppler ultrasound and treatment with transcatheter arterial embolization are described. [ABSTRACT FROM AUTHOR]