19 results on '"Nikolaus E. Wolter"'
Search Results
2. Olfaction and Gustation in Children With Primary Ciliary Dyskinesia
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Faisal Zawawi, Sharon Dell, Nikolaus E. Wolter, Blake C. Papsin, and Evan J. Propst
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children ,gustation ,olfaction ,primary ciliary dyskinesia ,U‐Sniff ,Otorhinolaryngology ,RF1-547 ,Surgery ,RD1-811 - Abstract
Abstract Objective Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder whereby abnormal cilia cause a wide array of respiratory tract manifestations including chronic rhinosinusitis. The purpose of this study was to determine whether olfaction and gustation are impaired in children with PCD. Study Design Cross‐sectional study. Setting Tertiary pediatric academic hospital. Methods Children with confirmed PCD based on having at least 1 of 3 approved diagnostic criteria as per The American Thoracic Society guidelines were recruited from The PCD Clinic in our tertiary care pediatric hospital. Odor identification ability was tested using the Universal Sniff (U‐Sniff) test and taste threshold was measured using an electrogustometer. The main outcome of this study is to determine the incidence of olfactory dysfunction in children with PCD and investigate if there is an associated gustatory dysfunction. Results Twenty‐five children participated (14 male, 11 female), The median age was 10.8 years (range: 4.1‐17.9 years). Only 4/25 (16%) complained of olfactory dysfunction prior to testing. None of the patients complained of dysgeusia. However, 48% (12/25) scored less than 7 on the U‐Sniff, signifying hyposmia or anosmia. In contrast, scores obtained by electrogustometry were in the normal range. There was no correlation between performance on the U‐Sniff and electrogustometry testing. Conclusion Olfactory impairment in children with PCD is common but underrecognized by patients. This is not associated with abnormal gustation. Among other, this places children with PCD at an increased risk with respect to smelling a fire or detecting spoiled or poisonous food.
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- 2023
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3. Button battery taping prevents oesophageal injury
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Nikolaus E Wolter, Jennifer K Wolter, Adrian L James, Olivia Ostrow, Nicole K McKinnon, Tobias Everett, Blake C Papsin, and Evan J Propst
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Eating ,Electric Power Supplies ,Esophagus ,Swine ,Pediatrics, Perinatology and Child Health ,Cadaver ,Animals ,Humans ,Foreign Bodies - Abstract
Most button battery (BB) ingestions in children are unwitnessed leading to prolonged exposures and severe complications. One third of ingestions occur from free BB, that are stored or awaiting disposal. Recommendations have been made to cover the terminals of discarded BB with adhesive tape; however, it is unclear if this practice prevents injury. Our aim was to determine if tape could prevent oesophageal injury in a cadaveric porcine model.Electrical, masking, packing and duct tape were compared. One BB was left untaped. Taped BBs were placed in a cadaveric porcine oesophagus controlled for temperature and humidification. Specimens were assessed at 0, 0.5, and hourly for 6 h by visual inspection, temperature and pH. BB voltage was measured before and after testing. All tests were repeated in triplicate.Oesophageal specimens demonstrated burn prevention in the packing and duct tape trials. Burns were seen in 2/3 trials with electrical tape and 3/3 trials with masking tape. pH remained neutral throughout the study for all packing and duct tape specimens. pH remained neutral initially for masking tape but increased rapidly to 12 by 2 h. There was no change in battery voltage for the packing tape and duct tape trials. There was a 16.3% reduction in voltage for masking tape which was similar to controls.Taping BB with packing tape and duct tape prevented oesophageal burns. This may provide a novel method of burn prevention for loose BB intended for disposal.
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- 2022
4. Decannulation following tracheostomy in children: A systematic review of decannulation protocols
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Nikolaus E. Wolter, Jackie Chiang, Evan J. Propst, Aaron St-Laurent, Michael R. Miller, Cora Mocanu, Jenny Shi, Rahul Verma, and Reshma Amin
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Capnography ,medicine.diagnostic_test ,Pulmonary care ,business.industry ,Polysomnography ,Patient demographics ,Airway obstruction ,medicine.disease ,Tracheostomy ,Clinical Protocols ,Bronchoscopy ,Pediatrics, Perinatology and Child Health ,Emergency medicine ,medicine ,Humans ,Tracheostomy care ,Child ,business ,Device Removal ,Tracheostomy tube ,Retrospective Studies - Abstract
Objective To provide a systematic review of the existing pediatric decannulation protocols, including the role of polysomnography, and their clinical outcomes. Methods Five online databases were searched from database inception to May 29, 2020. Study inclusion was limited to publications that evaluated tracheostomy decannulation in children 18 years of age and younger. Data extracted included patient demographics and primary indication for tracheostomy. Methods used to assess readiness for decannulation were noted including the use of bronchoscopy, tracheostomy tube modifications, and gas exchange measurements. After decannulation, details regarding mode of ventilation, location, and length of observation period, and clinical outcomes were also collected. Descriptive statistical analyses were performed. Results A total of 24 studies including 1395 children were reviewed. Tracheostomy indications included upper airway obstruction at a well-defined anatomic site (35%), upper airway obstruction not at a well-defined site (12%) and need for long-term ventilation and pulmonary care (53%). Bronchoscopy was routinely used in 23 of 24 (96%) protocols. Tracheostomy tube modifications in the protocols included capping (n = 20, 83%), downsizing (n = 14, 58%), and fenestrations (n = 2, 8%). Measurements of gas exchange included polysomnography (n = 13/18, 72%), oximetry (n = 10/18, 56%), blood gases (n = 3,17%), and capnography (n = 3, 17%). After decannulation, children in 92% of protocols were transitioned to room air. Observation period of 48 h or less was used in 76% of children. Conclusions There exists large variability in pediatric decannulation protocols. Polysomnography plays an integral role in assessing most children for tracheostomy removal. Evidence-based guidelines to standardize pediatric tracheostomy care remain an urgent priority.
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- 2021
5. Otolaryngology Manifestations of Primary Ciliary Dyskinesia: A Multicenter Study
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Sharon D. Dell, Faisal Zawawi, Nikolaus E. Wolter, Adam J. Shapiro, Maimoona A. Zariwala, Mariana M. Smith, Michael R. Knowles, Pilar Gajardo, Cinzia L. Marchica, Margaret W. Leigh, and Sam J. Daniel
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Pediatrics ,medicine.medical_specialty ,business.industry ,medicine.disease ,Article ,Otolaryngology ,03 medical and health sciences ,Cross-Sectional Studies ,0302 clinical medicine ,030228 respiratory system ,Otorhinolaryngology ,Multicenter study ,Quality of life ,Quality of Life ,otorhinolaryngologic diseases ,medicine ,Humans ,Surgery ,Sinusitis ,Child ,030223 otorhinolaryngology ,business ,Ciliary Motility Disorders ,Primary ciliary dyskinesia - Abstract
OBJECTIVE. This project aims to prospectively and objectively assess otolaryngological manifestations and quality of life of children with primary ciliary dyskinesia (PCD) and compare these findings with healthy pediatric controls. STUDY DESIGN. Cross-sectional. SETTING. Two high-volume pediatric PCD specialty centers. METHODS. Standardized clinical assessment; Sino-Nasal Outcome Test 22 (SNOT-22); Hearing Environment and Reflection Quality of Life (HEAR-QL); Reflux Symptom Index (RSI); standardized physical examination of the sinonasal, laryngeal, and otological systems; and investigations including pure-tone audiograms (PTAs) and sinonasal cultures were collected. RESULTS. Forty-seven children with PCD and 25 control participants were recruited. Children with PCD had more upper airway symptoms than healthy children. They had significantly higher scores in both SNOT-22 and RSI, indicating worse sinonasal and reflux symptoms, with worse quality of life on the HEAR-QL index compared to healthy children (P < .05). Fifty-two percent of children with PCD-related hearing loss were not aware of their hearing deficit that was present on audiological assessment, and only 23% of children who had ventilation tubes had chronic otorrhea, most of which was easily controlled with ototopic drops. Furthermore, although all children with PCD had chronic rhinosinusitis, only 36% of them were using topical nasal treatment. The most common bacteria cultured from the middle meatus were Staphylococcus aureus in 11 of 47 (23%), followed by Streptococcus pneumoniae in 10 of 47 (21%). CONCLUSION. This multisite cohort highlights the importance of otolaryngology involvement in the management of children with PCD. More rigorous otolaryngological management may lead to reductions in overall morbidity and improve quality of life for children with PCD.
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- 2021
6. <scp>Competency‐Based</scp> Assessment Tool for Pediatric Esophagoscopy: International Modified Delphi Consensus
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Erynne A. Faucett, Nikolaus E. Wolter, Karthik Balakrishnan, Stacey L. Ishman, Deepak Mehta, Sanjay Parikh, Lily H. P. Nguyen, Diego Preciado, Michael J. Rutter, Jeremy D. Prager, Glenn E. Green, Seth M. Pransky, Ravi Elluru, Murad Husein, Soham Roy, Kaalan E. Johnson, Jacob Friedberg, Romaine F. Johnson, Nancy M. Bauman, Charles M. Myer, Ellen S. Deutsch, Eric A. Gantwerker, J. Paul Willging, Catherine K. Hart, Robert H. Chun, Derek J. Lam, Jonathan B. Ida, John J. Manoukian, David R. White, Douglas R. Sidell, Christopher T. Wootten, Andrew F. Inglis, Craig S. Derkay, George Zalzal, David W. Molter, Jeffrey P. Ludemann, Sukgi Choi, Scott Schraff, Robin T. Cotton, Shyan Vijayasekaran, Carlton J. Zdanski, Hamdy El‐Hakim, Udayan K. Shah, Marlene A. Soma, Marshall E. Smith, Dana M. Thompson, Luv Ram Javia, Karen B. Zur, Steven E. Sobol, Christopher J. Hartnick, Reza Rahbar, Jean‐Philippe Vaccani, Benjamin Hartley, Sam J. Daniel, Ian N. Jacobs, Gresham T. Richter, Alessandro Alarcon, Matthew A. Bromwich, and Evan J. Propst
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Surgeons ,Consensus ,Esophagus ,Delphi Technique ,Otorhinolaryngology ,Surveys and Questionnaires ,Esophagoscopes ,Humans ,Internship and Residency ,Clinical Competence ,Esophagoscopy ,Child ,Foreign Bodies - Abstract
Create a competency-based assessment tool for pediatric esophagoscopy with foreign body removal.Blinded modified Delphi consensus process.Tertiary care center.A list of 25 potential items was sent via the Research Electronic Data Capture database to 66 expert surgeons who perform pediatric esophagoscopy. In the first round, items were rated as "keep" or "remove" and comments were incorporated. In the second round, experts rated the importance of each item on a seven-point Likert scale. Consensus was determined with a goal of 7 to 25 final items.The response rate was 38/64 (59.4%) in the first round and returned questionnaires were 100% complete. Experts wanted to "keep" all items and 172 comments were incorporated. Twenty-four task-specific and 7 previously-validated global rating items were distributed in the second round, and the response rate was 53/64 (82.8%) with questionnaires returned 97.5% complete. Of the task-specific items, 9 reached consensus, 7 were near consensus, and 8 did not achieve consensus. For global rating items that were previously validated, 6 reached consensus and 1 was near consensus.It is possible to reach consensus about the important steps involved in rigid esophagoscopy with foreign body removal using a modified Delphi consensus technique. These items can now be considered when evaluating trainees during this procedure. This tool may allow trainees to focus on important steps of the procedure and help training programs standardize how trainees are evaluated.5. Laryngoscope, 131:1168-1174, 2021.
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- 2020
7. Competency‐Based Assessment Tool for Pediatric Tracheotomy: International Modified Delphi Consensus
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Evan J. Propst, Nikolaus E. Wolter, Stacey L. Ishman, Karthik Balakrishnan, Ashley R. Deonarain, Deepak Mehta, George Zalzal, Seth M. Pransky, Soham Roy, Charles M. Myer, Michele Torre, Romaine F. Johnson, Jeffrey P. Ludemann, Craig S. Derkay, Robert H. Chun, Paul Hong, David W. Molter, Jeremy D. Prager, Lily H. P. Nguyen, Michael J. Rutter, Karen B. Zur, Douglas R. Sidell, Liane B. Johnson, Robin T. Cotton, Catherine K. Hart, J. Paul Willging, Carlton J. Zdanski, John J. Manoukian, Derek J. Lam, Nancy M. Bauman, Eric A. Gantwerker, Murad Husein, Andrew F. Inglis, Glenn E. Green, Luv Ram Javia, Scott Schraff, Marlene A. Soma, Ellen S. Deutsch, Steven E. Sobol, Jonathan B. Ida, Sukgi Choi, Trina C. Uwiera, Udayan K. Shah, David R. White, Christopher T. Wootten, Hamdy El‐Hakim, Matthew A. Bromwich, Gresham T. Richter, Shyan Vijayasekaran, Marshall E. Smith, Jean‐Philippe Vaccani, Christopher J. Hartnick, and Erynne A. Faucett
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Consensus ,Delphi Technique ,Electronic data capture ,assessment ,Modified delphi ,030230 surgery ,Pediatrics ,Delphi ,Likert scale ,objective structured assessment of technical skills ,03 medical and health sciences ,Tracheostomy ,0302 clinical medicine ,OSAT ,Humans ,Medicine ,Single-Blind Method ,Child ,030223 otorhinolaryngology ,OSATS ,computer.programming_language ,Surgeons ,Response rate (survey) ,education ,Medical education ,business.industry ,Evidence-based medicine ,Objective Structured Assessment of Technical Skill ,Global Rating ,tracheotomy ,Otorhinolaryngology ,Clinical Competence ,Pediatric tracheotomy ,Tracheotomy ,business ,computer - Abstract
Objectives/hypothesis Create a competency-based assessment tool for pediatric esophagoscopy with foreign body removal. Study design Blinded modified Delphi consensus process. Setting Tertiary care center. Methods A list of 25 potential items was sent via the Research Electronic Data Capture database to 66 expert surgeons who perform pediatric esophagoscopy. In the first round, items were rated as "keep" or "remove" and comments were incorporated. In the second round, experts rated the importance of each item on a seven-point Likert scale. Consensus was determined with a goal of 7 to 25 final items. Results The response rate was 38/64 (59.4%) in the first round and returned questionnaires were 100% complete. Experts wanted to "keep" all items and 172 comments were incorporated. Twenty-four task-specific and 7 previously-validated global rating items were distributed in the second round, and the response rate was 53/64 (82.8%) with questionnaires returned 97.5% complete. Of the task-specific items, 9 reached consensus, 7 were near consensus, and 8 did not achieve consensus. For global rating items that were previously validated, 6 reached consensus and 1 was near consensus. Conclusions It is possible to reach consensus about the important steps involved in rigid esophagoscopy with foreign body removal using a modified Delphi consensus technique. These items can now be considered when evaluating trainees during this procedure. This tool may allow trainees to focus on important steps of the procedure and help training programs standardize how trainees are evaluated. Level of evidence 5. Laryngoscope, 131:1168-1174, 2021.
- Published
- 2019
8. Catheter‐Guided Basket Removal of a Difficult‐to‐Reach Pediatric Airway Foreign Body
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Sharon L. Cushing, Nikolaus E. Wolter, Alexander Gabinet-Equihua, Evan J. Propst, and Nan Gai
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Male ,Rigid bronchoscopy ,medicine.medical_specialty ,Catheters ,business.industry ,Bronchi ,Foreign Bodies ,medicine.disease ,Surgery ,Trachea ,Catheter ,Treatment Outcome ,Otorhinolaryngology ,Foreign body aspiration ,Child, Preschool ,Bronchoscopy ,Humans ,Medicine ,Foreign body ,Pediatric airway ,business - Published
- 2021
9. Recurrent laryngeal nerve monitoring with surface electrodes in pediatric thyroid surgery
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Evan J. Propst, Nikolaus E. Wolter, Leona Ariel Tilis, Ethan Forde Glazman, Jonathan D. Wasserman, and Jonah Gorodensky
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Male ,medicine.medical_specialty ,Cord ,Adolescent ,Intraoperative Neurophysiological Monitoring ,medicine.medical_treatment ,030230 surgery ,03 medical and health sciences ,0302 clinical medicine ,Intubation, Intratracheal ,medicine ,Recurrent laryngeal nerve ,Humans ,Prospective Studies ,Thyroid Neoplasms ,Vocal cord paralysis ,Child ,030223 otorhinolaryngology ,Electrodes ,Paresis ,Recurrent Laryngeal Nerve ,business.industry ,Thyroid ,Area under the curve ,Thyroidectomy ,medicine.disease ,Surgery ,Dissection ,medicine.anatomical_structure ,Otorhinolaryngology ,Child, Preschool ,Female ,medicine.symptom ,business - Abstract
OBJECTIVE To prospectively evaluate 1) use of endotracheal tube (ETT) surface electrodes for recurrent laryngeal nerve (RLN) monitoring in thyroid surgery in children, and 2) effects of thyroid surgery on the RLN in children. METHODS Patients
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- 2019
10. Surgery for Obstructive Sleep Apnea in Obese Children: Literature Review and Meta‐analysis
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Theresa Holler, Patrick Scheffler, Indra Narang, Nikolaus E. Wolter, Stacey L. Ishman, Reshma Amin, and Evan J. Propst
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Pediatric Obesity ,Sleep Apnea, Obstructive ,Pediatrics ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Uvulopalatopharyngoplasty ,Apnea ,Overweight ,medicine.disease ,Obesity ,Obstructive sleep apnea ,Systematic review ,Otorhinolaryngology ,Intervention (counseling) ,Meta-analysis ,Humans ,Medicine ,Surgery ,medicine.symptom ,Child ,business - Abstract
Surgical intervention for obstructive sleep apnea (OSA) in overweight and obese children may not be as effective as it is in normal-weight children. The purpose of this study was to systematically review the effects of various surgical interventions for OSA in obese children and to meta-analyze the current data.PubMed, OVID, and Cochrane databases.Databases were searched for studies examining adenotonsillectomy, uvulopalatopharyngoplasty, supraglottoplasty, or tongue base surgeries and combinations in obese children with OSA. Adenotonsillectomy was the only procedure with enough data for meta-analysis; polysomnographic data were extracted and analyzed using a random-effects model.For adenotonsillectomy, 11 studies were included in the meta-analysis. Despite significant improvement in the apnea-hypopnea index (22.9 to 8.1 events/h, P.001), respiratory disturbance index (24.8 to 10.4 events/h, P.001), and oxygen saturation nadir (78.4% to 87.0%, P.001), rates of persistent OSA ranged from 51% to 66%, depending on the outcome criterion used. There was evidence of limited effectiveness for surgical interventions to treat OSA in obese children using uvulopalatoplasty (12.5%) and tongue base surgery (74%-88%).Surgical interventions for OSA in overweight and obese children are effective at reducing OSA but with higher rates of persistent OSA than reported for normal-weight children. However, the amount of reduction appears to vary by surgical procedure. More attention should be paid toward preoperative weight loss and patient selection, and parents should be provided with realistic postoperative expectations in this difficult-to-treat population.
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- 2019
11. Tracheo‐innominate fistula in children: A systematic review of literature
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Nikolaus E. Wolter, Evan J. Propst, Weining Yang, Daniel D. Lee, Anne Hseu, and Steven D. Rosenblatt
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Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Fistula ,medicine.medical_treatment ,MEDLINE ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Tracheotomy ,Bronchoscopy ,medicine ,Humans ,Child ,030223 otorhinolaryngology ,Brachiocephalic Trunk ,Vascular Fistula ,Tracheal Diseases ,medicine.diagnostic_test ,business.industry ,Evidence-based medicine ,medicine.disease ,Systematic review ,Otorhinolaryngology ,Child, Preschool ,Female ,Respiratory Tract Fistula ,Complication ,business ,Cohort study - Abstract
Objective Tracheo-innominate fistula (TIF) is a rare but fatal complication of tracheotomy. To date, there is a paucity of literature regarding pediatric TIFs. The objectives of this study were to conduct a systematic review of literature on pediatric TIF following tracheotomy and describe three demonstrative cases from our institutional experience. Methods We conducted a systematic review using MEDLINE, Embase, Cochrane Database of Systematic Reviews, Web of Science, and CINAHL. All studies with pediatric patients (under 18 years of age) who developed TIF following tracheotomy were included. Results Fifty-four publications met inclusion criteria, reporting on 77 cases. The most common indication for tracheotomy was prolonged intubation and the need for ventilatory support (38.6%), with neurological comorbidities being the most common indication (72.7%). The mean time to TIF was 395.7 days (95% confidence interval, 225.9-565.5). Fifty-four patients (70.1%) presented with massive hemorrhage, whereas 18 patients (23.3%) presented with a sentinel bleeding event. The most common diagnostic interventions were computed tomography scan with or without contrast and bronchoscopy (55.8%). A substantial number of patients did not have any investigations (41.6%). Surgical management occurred in 70.1% of patients. Mortality was 38.6% in reported cases with variable follow-up periods. Conclusion TIF may occur in long-term tracheostomy-dependent children, contrary to the conventionally described 3-week postoperative period. The mortality may not be as high as previously reported with timely intervention. Our results are limited by inherent risks of bias. Further research including well-designed cohort studies are needed to guide an evidence-based approach to TIF. Level of evidence NA Laryngoscope, 130:217-224, 2020.
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- 2019
12. Length of the Cricoid and Trachea in Children: Predicting Intubation Depth to Prevent Subglottic Stenosis
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Jonah Gorodensky, Evan J. Propst, and Nikolaus E. Wolter
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Male ,Rigid bronchoscopy ,medicine.medical_specialty ,Adolescent ,Subglottic stenosis ,medicine.medical_treatment ,Vocal Cords ,Cricoid Cartilage ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Patient age ,030225 pediatrics ,Bronchoscopy ,Intubation, Intratracheal ,medicine ,Humans ,Intubation ,Child ,Subglottis ,business.industry ,Infant, Newborn ,Infant ,Laryngostenosis ,medicine.disease ,Surgery ,Trachea ,medicine.anatomical_structure ,Otorhinolaryngology ,Endobronchial intubation ,Child, Preschool ,Vocal folds ,Cuff ,Linear Models ,Female ,business - Abstract
OBJECTIVE Define the length of the subglottis and trachea in children to predict a safe intubation depth. METHODS Patients
- Published
- 2021
13. Synthetic Simulator for Surgical Training in Tracheostomy and Open Airway Surgery
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Karen A. Gordon, Marvin Estrada, Anne Agur, Nikolaus E. Wolter, Robert V. Harrison, Ashley R. Deonarain, Thomas Looi, and Evan J. Propst
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Adult ,Animal Use Alternatives ,Male ,Models, Anatomic ,Adolescent ,medicine.medical_treatment ,Sus scrofa ,Manikins ,03 medical and health sciences ,Tracheostomy ,0302 clinical medicine ,Tracheotomy ,Cadaver ,Otolaryngologists ,medicine ,Content validity ,Animals ,Humans ,030223 otorhinolaryngology ,Simulation ,Face validity ,Surgeons ,business.industry ,Cartilage ,Laryngostenosis ,Gold standard (test) ,Plastic Surgery Procedures ,Costal cartilage ,Airway Obstruction ,Costal Cartilage ,Trachea ,High Fidelity Simulation Training ,medicine.anatomical_structure ,Otorhinolaryngology ,Thyroid Cartilage ,Models, Animal ,Printing, Three-Dimensional ,Tomography, X-Ray Computed ,Airway ,business ,Neck ,030217 neurology & neurosurgery - Abstract
OBJECTIVE(S) To create and validate a synthetic simulator for teaching tracheostomy and laryngotracheal reconstruction (LTR) using anterior costal cartilage and thyroid ala cartilage grafts. METHODS A late adolescent/adult neck and airway simulator was constructed based on CT scans from a cadaver and a live patient. Images were segmented to create three-dimensional printed molds from which anatomical parts were casted. To evaluate the simulator, expert otolaryngologists - head and neck surgeons performed tracheostomy and LTR using anterior costal cartilage and thyroid ala cartilage grafts on a live anesthetized porcine model (gold standard) followed by the synthetic simulator. They evaluated each model for face validity (realism and anatomical accuracy) and content validity (perceived effectiveness as a training tool) using a five-point Likert scale. For each expert, differences for each item on each simulator were compared using Wilcoxon Signed-Rank tests with Sidak correction. RESULTS Nine expert faculty surgeons completed the study. Experts rated face and content validity of the synthetic simulator an overall median of 4 and 5, respectively. There was no difference in scores between the synthetic model and the live porcine model for any of the steps of any of the surgical procedures. CONCLUSION The synthetic simulator created for this study has high face and content validity for tracheostomy and LTR with anterior costal cartilage and thyroid ala cartilage grafts and was not found to be different than the live porcine model for these procedures. LEVEL OF EVIDENCE 5 Laryngoscope, 131:E2378-E2386, 2021.
- Published
- 2021
14. Patterns and Predictors of Metastatic Spread to the Neck in Pediatric Thyroid Carcinoma
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Evan J. Propst, Nikolaus E. Wolter, Jonathan D. Wasserman, Bo-Yee Ngan, and Jonah Gorodensky
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Male ,medicine.medical_specialty ,Adolescent ,Lymphovascular invasion ,medicine.medical_treatment ,Mandibular nerve ,030209 endocrinology & metabolism ,Risk Assessment ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Recurrent laryngeal nerve ,Humans ,Thyroid Neoplasms ,Child ,business.industry ,Thyroid ,Thyroidectomy ,Neck dissection ,Surgery ,Dissection ,Treatment Outcome ,medicine.anatomical_structure ,Otorhinolaryngology ,Thyroid Cancer, Papillary ,Lymphatic Metastasis ,030220 oncology & carcinogenesis ,Resection margin ,Neck Dissection ,Female ,business ,Neck ,Follow-Up Studies - Abstract
OBJECTIVE Evaluate patterns and predictors of spread to the neck in pediatric metastatic differentiated thyroid carcinoma (DTC). METHODS Patients
- Published
- 2020
15. Primary parotid lymphoma presenting as a recurrent cystic mass: A case report
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Steven D. Rosenblatt, Nikolaus E. Wolter, Jacob R. Brodsky, and Bradford Siegele
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Pathology ,medicine.medical_specialty ,business.industry ,Lymphoblastic lymphoma ,medicine.disease ,Malignancy ,030205 complementary & alternative medicine ,Lymphoma ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Otorhinolaryngology ,Superficial Parotidectomy ,hemic and lymphatic diseases ,030220 oncology & carcinogenesis ,Medicine ,Cystic mass ,Bone marrow ,Presentation (obstetrics) ,Branchial cleft cyst ,business - Abstract
A 15-year-old boy was diagnosed with a cystic parotid mass, which was initially thought to be a first branchial cleft cyst. The mass was treated with antibiotics and fully resolved on examination and imaging. The mass returned, and a superficial parotidectomy was performed to remove the suspected branchial cleft cyst. Final pathology demonstrated a B-cell lymphoblastic lymphoma. Bilateral bone marrow biopsies and peripheral blood counts were negative for any malignancy. This case demonstrates a rare presentation of primary parotid B-cell lymphoblastic lymphoma that began as a fluctuating cystic parotid mass consistent in appearance with a first branchial cleft cyst. Laryngoscope, 128:998-1001, 2018.
- Published
- 2017
16. Malignant glomus tumors of the head and neck in children and adults: Evaluation and management
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Nikolaus E. Wolter, Antonio R. Perez-Atayde, Alexandria L. Irace, Darren B. Orbach, Christopher B. Weldon, Eelam Adil, Annette M. Werger, Carlos Rodriguez-Galindo, and Reza Rahbar
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medicine.medical_specialty ,Adjuvant chemotherapy ,business.industry ,medicine.medical_treatment ,fungi ,medicine.disease ,Glomus tumor ,Malignant Glomus Tumor ,Radiation therapy ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Pediatric patient ,0302 clinical medicine ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Chart review ,medicine ,Sarcoma ,Radiology ,business ,Head and neck - Abstract
Objectives/Hypothesis To describe our current multidisciplinary approach to pediatric malignant glomus tumors of the head and neck and review the current literature. Study Design Retrospective chart review at a tertiary referral children's hospital and a comprehensive literature review. Methods A comprehensive literature search of PubMed, Embase, Web of Science, Google Scholar, and EBSCO with respect to malignant glomus tumors of the head and neck was conducted. We obtained expert input from other pertinent specialties, including oncology, pathology, and radiology. To highlight the difficulty of evaluation and management of these patients, we also present a pediatric patient with a left neck malignant glomus tumor and lung metastases. Results Only two cases of pediatric malignant glomus tumor (including our own) have been reported in the English literature. Overall, 14 malignant glomus tumors have been reported in the head and neck (11 primary and three metastatic). Surgical resection is the mainstay of treatment, but local recurrence is common (five of 11, 45%). Conclusions Malignant glomus tumor of the head and neck is an extremely rare tumor in children. Evaluation consists of imaging, and tissue biopsy is necessary for definitive diagnosis. Management options include surgical resection with or without an adjuvant chemotherapy protocol similar to those designed for sarcoma. Additional reports are necessary so that we may determine the utility, if any, of radiotherapy in the management of this tumor. Laryngoscope, 2017
- Published
- 2017
17. Pediatric ossiculoplasty with titanium total ossicular replacement prosthesis
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Theresa Holler, Adrian L. James, Sharon L. Cushing, Blake C. Papsin, Karen A. Gordon, Neil K. Chadha, and Nikolaus E. Wolter
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medicine.medical_specialty ,business.industry ,Hearing loss ,medicine.medical_treatment ,Cholesteatoma ,Total ossicular replacement prosthesis ,medicine.disease ,Prosthesis ,Surgery ,Bone conduction ,Otorhinolaryngology ,Hearing level ,Medicine ,medicine.symptom ,business ,A titanium ,Audiometric testing - Abstract
Objectives/Hypothesis To assess the medium-term efficacy of total ossicular reconstruction with a titanium total ossicular replacement prosthesis (TORP) in children. Study Design Case series. Methods A consecutive series of children receiving an adjustable-length titanium TORP was identified from a prospective surgical and audiological database. Audiometric testing was obtained preoperatively, 2 months postoperatively, and subsequently at 6- to 12-month intervals. Four-frequency pure-tone averages (PTA) were determined for air conduction (AC) and bone conduction thresholds, as well as air–bone gap (ABG). Pre- and postoperative measures were compared to determine degree of improvement. The proportion with successful outcome (defined as ≤ 30 dB hearing level [HL] AC) was determined over time with Kaplan-Meier analysis. Results Seventy-five TORPs were inserted in 71 children aged 7 to 18 years, with a median follow-up of 2.7 years (0.6–5.5 years). The mean postoperative PTA AC threshold and ABG at 1 year were 35 dB HL and 29 dB, respectively, with ABG closure of 14 dB. The maximum gain in AC was 40 dB, achieved in eight (11%) cases. Successful outcome was seen in 50% of children at first follow-up. Over the following 1 to 3 years, hearing levels deteriorated to AC > 30 dB HL in an additional 10% of patients. Four patients had revision surgery, one for prosthesis extrusion and three for a lack of improvement in hearing. Conclusions Titanium TORPs offer children an effective method of ossicular reconstruction, with infrequent extrusion at least in the short term. The hearing improvement achieved in the early postoperative period appears to be maintained over the first year but may not be sustained over longer time periods. Level of Evidence 4. Laryngoscope, 125:740–745, 2015
- Published
- 2014
18. Polysomnography: Assessment of decannulation readiness in chronic upper airway obstruction
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Nikolaus E. Wolter and Jennifer Anderson
- Subjects
Adult ,Male ,Larynx ,medicine.medical_specialty ,Time Factors ,Polysomnography ,medicine.medical_treatment ,Laryngoscopy ,Risk Assessment ,Severity of Illness Index ,Cohort Studies ,Positive-Pressure Respiration ,Young Adult ,Sex Factors ,Tracheotomy ,Intubation, Intratracheal ,medicine ,Humans ,Continuous positive airway pressure ,Device Removal ,Aged ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,Age Factors ,Middle Aged ,Airway obstruction ,medicine.disease ,Surgery ,Airway Obstruction ,Obstructive sleep apnea ,Treatment Outcome ,medicine.anatomical_structure ,Otorhinolaryngology ,Anesthesia ,Chronic Disease ,Female ,business ,Laryngeal Stenosis ,Follow-Up Studies - Abstract
Objectives/Hypothesis To evaluate the clinical value of polysomnography in patients with a tracheotomy due to chronic upper airway obstruction prior to attempting decannulation. Study Design Retrospective chart review. Methods Subjects with chronic upper airway obstruction were identified using a clinical database between 2000 and 2014. All subjects had a tracheotomy, were assessed by the senior author in a tertiary care academic center, and underwent polysomnography prior to attempting decannulation. Patients were excluded if they did not undergo polysomnography or had severe obstructive sleep apnea as the primary indication for tracheotomy. Results Fifteen patients were identified. The majority (87.5%) of patients were successfully decannulated after their first polysomnography showed acceptable results when carried out with the tracheotomy occluded. Obstructive sleep apnea was identified in four of the nine patients who tolerated overnight tracheotomy occlusion, and continuous positive airway pressure (CPAP) was initiated. An additional four of the remaining six patients were decannulated after subsequent polysomnography demonstrated improvement with CPAP, and two required an additional airway procedure. Conclusions Chronic upper airway obstruction requiring tracheotomy can be challenging to treat and successfully decannulate. Indirect laryngoscopy is essential to evaluate the anatomy of the larynx; however, it cannot assess potential increased obstruction during sleep. The study indicates that polysomnography can assist with the evaluation of decannulation readiness in patients with chronic upper airway obstruction as an adjunct measure in addition to imaging and laryngoscopy. Level of Evidence 4 Laryngoscope, 124:2574–2578, 2014
- Published
- 2014
19. Middle ear aneurysm treated with an innovative, vessel-preserving, aneurysm-occluding stent
- Author
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Sean P. Symons, Peter Howard, Joseph Chen, Elisa Fuller, Aditya Bharatha, Thomas R. Marotta, Robert A. Willinsky, Jordan Hochman, Nikolaus E. Wolter, and Cian O'Kelly
- Subjects
medicine.medical_specialty ,business.industry ,Vascular disease ,medicine.medical_treatment ,Stent ,Blood flow ,medicine.disease ,Thrombosis ,Surgery ,medicine.anatomical_structure ,Aneurysm ,Otorhinolaryngology ,cardiovascular system ,medicine ,Middle ear ,cardiovascular diseases ,Radiology ,business ,Occlusion stent ,Blood vessel - Abstract
Middle ear aneurysms are rare and difficult to treat. An innovative, parent vessel-preserving, aneurysm occlusion stent is a treatment alternative. It redirects blood flow away from the aneurysm, resulting in stasis within, and ultimate aneurysm thrombosis. Concurrent coiling is not needed with this stent, eliminating the risk of coils extruding or migrating, or acting as a nidus for infection in the middle ear. We review a successful treatment using this device.
- Published
- 2010
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