1. Two new iridoid glycosides from the whole plant of Rehmania piasezkii.
- Author
-
Zhou, Jie, Shi, Guo-Ru, Zhang, Wan-Qi, Yu, De-Quan, and Liu, Yan-Fei
- Subjects
CHINESE medicine ,RESEARCH funding ,NUCLEAR magnetic resonance spectroscopy ,HERBAL medicine ,SPECTROPHOTOMETERS ,THIN layer chromatography ,DESCRIPTIVE statistics ,PLANT extracts ,CELL lines ,MEDICINAL plants ,GLYCOSIDES ,MOLECULAR structure ,BIOLOGICAL assay ,HEPATOCELLULAR carcinoma ,ACETAMINOPHEN - Abstract
Two new iridoid glycosides, piasezkiiosides A (1) and B (2), were isolated from aqueous extract of the whole plant of Rehmannia piasezkii. Their structures were established from the spectroscopic data, chemical transformation, and X-ray diffraction analysis. Compound 1 exhibited weak hepatoprotective activity against APAP-induced HepG2 cell damage. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF