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C28 sterols with a cyclopentane ring at C-22 and 26 from cape gooseberry (berries of Physalis pubeacens L.).
- Source :
-
Journal of Asian Natural Products Research . Sep2010, Vol. 12 Issue 9, p752-759. 8p. 3 Diagrams, 3 Charts. - Publication Year :
- 2010
-
Abstract
- Two new C28 sterols with a cyclopentane ring at C-22 and 26, alkesterol A (1) and alkesterol B (2), along with β-sitosterol (3), were isolated from the berries of Physalis pubeacens L. (cape gooseberry). The structures of the new compounds were established by HR-EI-MS, 1D and 2D (1H-1H COSY, HSQC, HMBC) NMR experiments. The known compound was identified by comparison of spectral data with published references. The two new compounds showed some cytotoxic activities by MTT assay. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANTINEOPLASTIC agents
*BERRIES
*CHROMATOGRAPHIC analysis
*COLORIMETRY
*HERBAL medicine
*MASS spectrometry
*CHINESE medicine
*MOLECULAR structure
*NUCLEAR magnetic resonance spectroscopy
*PHARMACEUTICAL chemistry
*RESEARCH funding
*TOXICITY testing
*PHYTOCHEMICALS
*ANALYTICAL chemistry
*PHARMACODYNAMICS
Subjects
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 12
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 53564765
- Full Text :
- https://doi.org/10.1080/10286020.2010.497657