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Polygonum hydropiper L. (Polygonaceae) (PH) is a traditional Chinese traditional medicine with a pungent flavor and mild drug properties. PH is mainly distributed in the channel tropism in the stomach and large intestine. PH has multiple uses and can be used to treat a variety of diseases for a long time. This review summarizes the phytochemical and pharmacological activities, and applications of PH from 1980 to 2022. We also provide suggestions for promoting further research and developing additional applications of PH. The data and information on PH from 1980 to 2022 reviewed in this article were obtained from scientific databases, including Science Direct, PubMed, Science Citation Index, SciFinder Scholar (SciFinder), Springer, American Chemical Society (ACS) Publications, and China National Knowledge Infrastructure (CNKI), etc. Some information was obtained from classic literature on traditional Chinese medicines. The search terms were Polygonum hydropiper, phytochemistry compositions of Polygonum hydropiper, pharmacological activities of Polygonum hydropiper, and applications of Polygonum hydropiper. The comprehensive analysis of the literature resulted in 324 compounds being isolated, identified, and reported from PH. Regarding traditional uses, the majority of phytochemical and pharmacological studies have indicated the diverse bioactivities of PH extracts, flavonoids, and volatile oil elements, including antibacterial, antifungal, insecticidal, antioxidant, and anti-inflammatory. PH has a long history of diversified medicinal uses, some of which have been verified in modern pharmacological studies. Further detailed studies are required to establish scientific and reasonable quality evaluation standards and action mechanisms of active constituents from PH. [ABSTRACT FROM AUTHOR]

Tetraclinis articulata is a medicinal plant distributed from northwestern Africa to southwestern Europe. This article reports previous investigations on T. articulata regarding its taxonomy, botanical description, geographical distribution, traditional use, phytochemistry, biological effects, toxicology, nutritional value, and economic interest. The search of data was based on several scientific databases such as Scopus, Wiley Online, Web of Science, Google Scholar, PubMed, ScienceDirect, SciFinder, and SpringerLink. Indeed, several biological activities were reported for T. articulata extracts and EOs, including antioxidant, antibacterial, antifungal, anticorrosion, cytotoxic, insecticidal, leishmanicidal, larvicidal, anti-inflammatory, antidiarrheal, vasorelaxant, and protective activities. Moreover, some toxicological reports indicated that T. articulata does not present any toxicity. However, other investigations regarding the toxicity, the pharmacokinetic and the pharmacodynamics of T. articulata and its major bioactive compounds are required to validate its pharmacological use. T. articulata also contains some nutritional elements such as mineral compounds, sugar and proteins which could indicate its potential use in the nutraceutical field. All these properties to T. articulata attributed a major economic interest which is used actually in the manufacture of luxury varnishes, pharmaceutical products and in other industrial uses, it is also used in powder form to prepare the surface of certain paper. [ABSTRACT FROM AUTHOR]

Context: Kniphofia (Asphodelaceae) is found mainly in South Africa and Tropical Africa. Malaria, hepatitis B, blood purifier, cancer, eczema, and female infertility have all been traditionally treated using this genus. Objective: The current review provides a complete and up-to-date compilation of documented traditional medicinal uses, phytochemicals, and pharmacological activities of the genus. Method: Relevant literature was collected by searching the major electronic scientific databases including PubMed, Science Direct, Web of Science, and Google Scholar using appropriate keywords ethnomedicinal studies, phytochemical investigations, and pharmacological activities of Kniphofia species. The search strategy included all articles with descriptors that were available until November 30, 2021. Only published works in English were used for this study. The data were collected using textual descriptions of the studies, tabulation, grouping, and figures. Result: At present, more than 40 compounds have been isolated from different parts of Kniphofia species. The major compounds isolated from the Kniphofia species are monomeric anthraquinones and dimeric anthraquinones. Pharmacologically the extracts and isolated compounds showed antioxidant, antimalarial, antiproliferative, anti-HIV-1, anti-leukotriene, and cytotoxic activity. The genus afforded exemplary drug leads such as knipholone and knipholone anthrone with anti-HIV-1, antimalarial and cytotoxicity activity. Conclusions: Kniphofia species have traditionally been used to treat a variety of diseases. Pharmacological actions of phytochemicals were shown to be promising. Despite this, considering the genus's inclusion on the red data list of South Africa, it deserves more attention. In order to find novel drug candidates, more studies on promising crude extracts and compounds are needed. [ABSTRACT FROM AUTHOR]

Context: Tadehagi triquetrum (Linn.) Ohashi (Fabaceae) (TT), is a traditional herbal medicine used especially in China's ethnic-minority communities, such as the Zhuang, Dai, Li and Wa aeras. As an ethnic medicine, it has long been used to treat various diseases. Objective: This review summarised the phytochemical and pharmacological progress on TT from 1979 to October, 2021 by highlighting its chemical classification, structural features, pharmacological applications and folk applications to provide inspirations and suggestions for accelerating further research of this traditional phytomedicine. Methods: The information on TT in this article has been obtained using these multiple scientific databases including Scifinder, Web of Science, ScienceDirect, Wiley, ACS publications, Springer, PubMed, China Knowledge Resource Integrated Database from the China National Knowledge Infrastructure (CNKI), Google Scholar and Baidu Scholar. Some information was also collected from classic literature on traditional Chinese medicines. Results: More than 70 compounds have been isolated and reported from TT to date by the comprehensive analysis of the current literature. A large number of traditional uses and pharmacological studies have exhibited diversified bioactivities of various TT extracts and its metabolites, including anti-inflammatory, antimicrobial, anti-hepatitis B virus, hepatoprotective, insecticidal, etc. Conclusions: As a famous traditional medicine with a long history, TT has various medicinal uses and some of them have been supported by modern pharmacological researches. Further detailed studies on the action mechanisms, pharmacodynamics and structure-function relationships of single compounds or active constituents from TT are also required. [ABSTRACT FROM AUTHOR]

Skimmia laureola (Family: Rutaceae), commonly known as Kedarpati is an evergreen shrub native to the Himalayan regions. Different parts of the plant have traditionally been used as a remedy for numerous diseases including stomach ache, dysentery, nausea, smallpox, body pain, flu, and diabetes. S. laureola has been investigated for its chemical composition and biological activities by various researchers. The essential oil has been evaluated for various pharmacological properties including insecticidal, antifungal, anthelmintic, antibacterial, and antioxidant activities. A thorough bibliographic investigation was carried out by analyzing worldwide accepted scientific databases including SciFinder, ScienceDirect, PubMed, Google Scholar, and Wiley Online as well as offline sources. The present review is aimed to provide an updated and comprehensive overview of traditional uses, chemical constituents, and biological activities of the essential oil of S. laureola to highlight its ethnopharmacological importance, to explore its chemo-therapeutic potentials, and to provide a basis for future research. [ABSTRACT FROM AUTHOR]