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1. C28 sterols with a cyclopentane ring at C-22 and 26 from cape gooseberry (berries of Physalis pubeacens L.).

Author

Xu, Qiong-Ming, Liu, Yan-Li, Feng, Yu-Lin, Li, Xiao-Ran, and Yang, Shi-Lin

Subjects
*ANTINEOPLASTIC agents, *BERRIES, *CHROMATOGRAPHIC analysis, *COLORIMETRY, *HERBAL medicine, *MASS spectrometry, *CHINESE medicine, *MOLECULAR structure, *NUCLEAR magnetic resonance spectroscopy, *PHARMACEUTICAL chemistry, *RESEARCH funding, *TOXICITY testing, *PHYTOCHEMICALS, *ANALYTICAL chemistry, *PHARMACODYNAMICS
Abstract

Two new C28 sterols with a cyclopentane ring at C-22 and 26, alkesterol A (1) and alkesterol B (2), along with β-sitosterol (3), were isolated from the berries of Physalis pubeacens L. (cape gooseberry). The structures of the new compounds were established by HR-EI-MS, 1D and 2D (1H-1H COSY, HSQC, HMBC) NMR experiments. The known compound was identified by comparison of spectral data with published references. The two new compounds showed some cytotoxic activities by MTT assay. [ABSTRACT FROM AUTHOR]

Published
2010
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