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2. Analysis of inter-regional effects caused by the wide-area operation of the power grid in Japan: an implication for carbon pricing schemes

Author

Satoshi Nakano and Ayu Washizu

Subjects
Consumption (economics), Economics and Econometrics, Computer science, business.industry, Scale (chemistry), 0211 other engineering and technologies, Distribution (economics), 02 engineering and technology, 010501 environmental sciences, Management, Monitoring, Policy and Law, Environmental economics, 01 natural sciences, Energy policy, Renewable energy, Production (economics), Table (database), 021108 energy, Power grid, business, 0105 earth and related environmental sciences
Abstract

In this research, we examine the socioeconomic impact of carbon pricing (CP) mechanism-related energy policies under the technical constraints of Japan. For this, we have created the Inter-Regional Input–Output Table for a Next Generation Energy System (IONGES) in 2030, considering these technical constraints. Namely, we created three Inter-Regional IONGESs with different assumptions for the wide-area operation of the power grid. The results show that the technical constraints of the power grid influence the interregional distribution of renewable energy. Top ten regional renewable energy sectors (TOP10), which has a large production scale, account for approximately 54% of renewable energy generation, which was found to be biased. From the viewpoint of consumers in each region, we analyzed the share of the electricity cost required to support their consumption. If the CP mechanism is implemented under the technical constraints of the current power grid, consumers in each region will be impacted unequally. However, it was found that such inequality will be solved under the wide-area operation of the power grid.

Published
2020
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3. Physiologic Leg Bowing is not a Physiologic Condition but Instead is Associated with Vitamin D Disorders in Toddlers

Author

Mitsuyoshi Suzuki, Yuko Sakamoto, Satoshi Nakano, Akifumi Tokita, Masahiko Nozawa, Muneaki Ishijima, Lizu Liu, Sung-Gon Kim, Kazuo Kaneko, and Toshiaki Shimizu

Subjects
Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Genu varum, Parathyroid hormone, 030209 endocrinology & metabolism, Rickets, Gastroenterology, Phosphates, Young Adult, 03 medical and health sciences, Child Development, 0302 clinical medicine, Endocrinology, Japan, Genu Varum, Internal medicine, Prevalence, medicine, Vitamin D and neurology, Humans, Blood test, Orthopedics and Sports Medicine, Vitamin D, Child, medicine.diagnostic_test, business.industry, Metabolic disorder, Age Factors, Odds ratio, Alkaline Phosphatase, Vitamin D Deficiency, medicine.disease, body regions, Bone Diseases, Metabolic, Parathyroid Hormone, Case-Control Studies, Child, Preschool, Alkaline phosphatase, Calcium, Female, 030101 anatomy & morphology, medicine.symptom, business
Abstract

When children around 2-year-old show leg bowing without lower-limb radiographic abnormalities for rickets, the leg bowing is classified as “physiologic” genu varum without conducting a blood test. However, it has recently been suggested that toddlers who are diagnosed with physiologic genu varum may in fact have some form of bone metabolic disorder. In this 1:2 case–control study, blood samples were obtained from 33 toddlers with genu varum without radiographic abnormalities for rickets and 66 age- and gender-matched healthy children. Serum alkaline phosphatase (sALP), intact parathyroid hormone (siPTH), 25-hydroxy vitamin D [s25(OH)D], calcium (sCa), and inorganic phosphate (sP) were measured. s25(OH)D of the subjects with genu varum (24.8 ng/ml) were significantly lower than those of the control (33.6 ng/ml) (p

Published
2019
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4. Real-time quantitative PCR analysis of endoscopic biopsies for diagnosing CMV gastrointestinal disease in non-HIV immunocompromised patients: a diagnostic accuracy study

Author

Hiroshi Seno, Masaki Yamamoto, Minoru Matsuura, Satoshi Ichiyama, Satoshi Nakano, Miki Nagao, Yasuhiro Tsuchido, and Yasufumi Matsumura

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, Gastrointestinal Diseases, Biopsy, Congenital cytomegalovirus infection, Cytomegalovirus, HIV Infections, Quantitative PCR analysis, Real-Time Polymerase Chain Reaction, Sensitivity and Specificity, Inflammatory bowel disease, Gastroenterology, Immunocompromised Host, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Retrospective Studies, Receiver operating characteristic, business.industry, Reproducibility of Results, Endoscopy, General Medicine, Middle Aged, Viral Load, medicine.disease, Confidence interval, Cross-Sectional Studies, Infectious Diseases, Real-time polymerase chain reaction, ROC Curve, Gastrointestinal disease, Cytomegalovirus Infections, DNA, Viral, Female, 030211 gastroenterology & hepatology, Histopathology, business
Abstract

Cytomegalovirus gastrointestinal diseases (CMV-GIDs) are end-organ diseases of the gastrointestinal (GI) tract caused by CMV in immunocompromised patients. We aimed to evaluate the performance of quantitative polymerase chain reaction (qPCR) on endoscopic biopsies. We retrospectively reviewed the qPCR data on endoscopic biopsies in nonhuman immunodeficiency virus (HIV) immunocompromised patients between January 2009 and May 2015. The performance of the qPCR for CMV-GID was evaluated with the sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC). A total of 195 patients were included, and 28 patients with confirmed CMV-GID were identified. The AUROC of the qPCR was 0.935 (95% confidence interval [CI], 0.885 to 0.985), the sensitivity was 89.3% (95% CI, 71.8 to 97.7%), and the specificity was 85.6% (95% CI, 79.4 to 97.6%) with a cutoff value of 180 copies/μg DNA. The proportion of patients with inflammatory bowel disease in the histopathology-negative, PCR-positive group was smaller than that in the histopathology-positive group (10.7 vs 35.0%, p = 0.026), but other characteristics were not significantly different. The use of qPCR on endoscopic biopsies demonstrated good diagnostic performance for detecting CMV in non-HIV immunocompromised patients. It may increase the diagnostic yield when combined with a conventional histopathology.

Published
2018
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5. A refractory hypertensive patient with fibromuscular dysplasia and multicystic dysplastic kidney

Author

Shin Takahashi, Satoshi Nakano, Yurie Takizawa, and Kotaro Oyama

Subjects
Male, medicine.medical_specialty, Adolescent, Computed Tomography Angiography, 030232 urology & nephrology, Multicystic dysplastic kidney, Fibromuscular dysplasia, 030204 cardiovascular system & hematology, Renal Artery Obstruction, urologic and male genital diseases, Renal artery stenosis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine.artery, Fibromuscular Dysplasia, Humans, Medicine, Multicystic Dysplastic Kidney, Radiology, Nuclear Medicine and imaging, Renal artery, Kidney, medicine.diagnostic_test, business.industry, Balloon catheter, Ultrasonography, Doppler, General Medicine, medicine.disease, Stenosis, medicine.anatomical_structure, Hypertension, Angiography, Cardiology, Atrophy, business
Abstract

The case of a 16-year-old male patient with left renal artery stenosis due to fibromuscular dysplasia (FMD) and an atrophic kidney due to a right multicystic dysplastic kidney (MCDK) who presented with refractory hypertension is reported. On continuous Doppler imaging, the peak systolic velocity (PSV) at the stenotic site of the left renal artery was 404 cm/s. The FMD formed a "string-of-beads" appearance on computed tomographic angiography (CTA) and renal artery angiography. Percutaneous transluminal renal angioplasty (PTRA) with a balloon catheter was performed, after which the left renal artery returned to near normal, and his blood pressure decreased to within the normal range. In this case, the main cause of refractory hypertension was considered to have been renal artery stenosis due to left FMD.

Published
2018
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6. Bilateral multifactor CES general equilibrium with state-replicating Armington elasticities

Author

Jiyoung Kim, Satoshi Nakano, and Kazuhiko Nishimura

Subjects
General Economics (econ.GN), General equilibrium theory, Renewable Energy, Sustainability and the Environment, Calibration (statistics), Elasticity of substitution, Economics, Econometrics and Finance (miscellaneous), Tariff, State (functional analysis), Development, Quantitative Finance - Economics, Regression, FOS: Economics and business, Urban Studies, Bilateral trade, Economics, Econometrics, Market share
Abstract

We measure elasticity of substitution between foreign and domestic commodities by two-point calibration such that the Armington aggregator can replicate the two temporally distant observations of market shares and prices. Along with the sectoral multifactor CES elasticities which we estimate by regression using a set of disaggregated linked input--output observations, we integrate domestic production of two countries, namely, Japan and the Republic of Korea, with bilateral trade models and construct a bilateral general equilibrium model. Finally, we make an assessment of a tariff elimination scheme between the two countries.

Published
2017
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7. Changes in consumer behavior as a result of the Home Appliance Eco-Point System: an analysis based on micro data from the Family Income and Expenditure Survey

Author

Ayu Washizu and Satoshi Nakano

Subjects
Economics and Econometrics, Government, Economic growth, Public economics, 020209 energy, Subsidy, 02 engineering and technology, Energy consumption, 010501 environmental sciences, Management, Monitoring, Policy and Law, Equivalent variation, Family income, 01 natural sciences, Demand curve, 0202 electrical engineering, electronic engineering, information engineering, Economics, Consumer behaviour, 0105 earth and related environmental sciences, Social policy
Abstract

The Home Appliance Eco-Point System refers to the project executed by the Japanese government from May 2009 to March 2011. The system, while showing signs of slowing down in the latter half of the implementation period, has, to a certain extent, facilitated a demand-promoting effect. Those effects are relatively large, particularly in regions outside the greater national capital district and in households with senior citizens. It can be attributed to the Eco-Point system that “electrical appliances became widespread in those households that had rarely made an effort to save on energy consumption”. Moreover, it can be inferred that the Eco-Point system enhanced the relative utility levels for refrigerators in households in major cities, and for air conditioners and televisions in households with elderly members in small cities. Thus, when implementing environmental policy, we believe that the policy effects can be made more impactful by reasonably determining the household types to target for each good, by setting the subsidy rates according to the differences in the targeted households, and by considering the desirable method of the information provision policy.

Published
2016
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8. Preferential dissolution of SiO2 from enstatite to H2 fluid under high pressure and temperature

Author

Taku Okada, Hiroaki Ohfuji, Hisako Hirai, Ayako Shinozaki, Takehiko Yagi, Hiroyuki Kagi, and Satoshi Nakano

Subjects
010504 meteorology & atmospheric sciences, Chemistry, Analytical chemistry, Mineralogy, Forsterite, engineering.material, 010502 geochemistry & geophysics, 01 natural sciences, Geochemistry and Petrology, Phase (matter), Coesite, engineering, Enstatite, General Materials Science, Periclase, Dissolution, Quartz, 0105 earth and related environmental sciences, Stishovite
Abstract

Stability and phase relations of coexisting enstatite and H2 fluid were investigated in the pressure and temperature regions of 3.1–13.9 GPa and 1500–2000 K using laser-heated diamond-anvil cells. XRD measurements showed decomposition of enstatite upon heating to form forsterite, periclase, and coesite/stishovite. In the recovered samples, SiO2 grains were found at the margin of the heating hot spot, suggesting that the SiO2 component dissolved in the H2 fluid during heating, then precipitated when its solubility decreased with decreasing temperature. Raman and infrared spectra of the coexisting fluid phase revealed that SiH4 and H2O molecules formed through the reaction between dissolved SiO2 and H2. In contrast, forsterite and periclase crystals were found within the hot spot, which were assumed to have replaced the initial orthoenstatite crystals without dissolution. Preferential dissolution of SiO2 components of enstatite in H2 fluid, as well as that observed in the forsterite H2 system and the quartz H2 system, implies that H2-rich fluid enhances Mg/Si fractionation between the fluid and solid phases of mantle minerals.

Published
2015
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9. Development and evaluation of MALDI-TOF MS-based serotyping for Streptococcus pneumoniae

Author

Tomoyuki Yunoki, S. Takakura, Masayuki Yamamoto, Taro Noguchi, Satoshi Ichiyama, Gou Hotta, Takao Fujisawa, Bin Chang, Shigeru Suga, Miki Nagao, Yasufumi Matsumura, Karin Kato, Toshiaki Ihara, Makoto Ohnishi, Satoshi Nakano, and Yutaka Ito

Subjects
Microbiology (medical), Serotype, medicine.medical_specialty, Validation study, Pneumococcal disease, Adolescent, Biology, medicine.disease_cause, Pneumococcal Infections, Microbiology, Medical microbiology, Japan, Streptococcus pneumoniae, medicine, Humans, Serotyping, Child, Infant, Newborn, Infant, General Medicine, medicine.disease, Infant newborn, Virology, Pneumococcal infections, Infectious Diseases, Child, Preschool, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Epidemiological Monitoring, Validation cohort
Abstract

Surveillance of Streptococcus pneumoniae serotypes is important for the successful implementation of vaccination strategies to prevent the spread of invasive pneumococcal diseases. The standard method of serotyping of pneumococcal isolates is the phenotypic Neufeld test, which is cost- and labor-intensive. Recently, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been implemented as a rapid, simple and inexpensive method for identifying species. We evaluated the performance of MALDI-TOF MS for serotyping ten major serotypes of S. pneumoniae in Japan (serotypes 3, 6B, 15A, 15C, 19A, 19 F, 23A, 24 F, 35B and 38) using the Biotyper and ClinProTools. After optimizing the settings, we validated their serotyping performance for serotypes 3, 15A and 19A using a separate set of isolates that were not used in the creation of the classification algorithms. A total of 574 isolates of S. pneumoniae collected from Japanese nationwide surveillance studies were included. Of these, 407 isolates belonged to the ten major serotypes. Biotyper and ClinProTools correctly identified 77.9 % and 84.0 %, respectively, of the ten major serotype isolates. The validation analysis included a total of 113 isolates of the serotypes 3, 15A and 19A isolates. Biotyper and ClinProTools correctly identified 85.0 % and 69.9 % of the validation cohort isolates, respectively. MALDI-TOF MS has the potential to discriminate the ten major S. pneumoniae serotypes prevalent in Japan.

Published
2015
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10. Marginal Value Estimation for the Attributes of the Tameikes via Choice Experiment

Author

Kazuhiko Nishimura and Satoshi Nakano

Subjects
Estimation, Willingness to pay, Mixed logit, Random parameter logit, Economics, Econometrics, Marginal value, Rural area, Water Science and Technology, Civil and Structural Engineering, Valuation (finance)
Abstract

In this study, we conducted a choice experiment for estimating the marginal willingness to pay for the different attributes of the small-scale water reservoirs, known as Tameikes, which are prevalent throughout Japan’s inhabitable rural areas. By using Internet surveys, we collected unlabeled five-way choice data from 16,000 respondents residing in the 26 Tameike-abundant prefectures out of the total 47. In this study, we report on the random parameters logit estimates with interacting terms that indicate the differences in the valuation of Tameike attributes with respect to the differences in the respondents’ socio-demographiccharacteristics.

Published
2013
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11. Pressure responses of portlandite and H–D isotope effects on pressure-induced phase transitions

Author

Hiroyuki Kagi, Daichi Ushijima, Takehiko Yagi, Kazuki Komatsu, Takaya Nagai, Asami Sano-Furukawa, Riko Iizuka, and Satoshi Nakano

Subjects
Diffraction, Phase transition, Analytical chemistry, chemistry.chemical_element, engineering.material, Portlandite, Diamond anvil cell, symbols.namesake, chemistry, Geochemistry and Petrology, Phase (matter), Kinetic isotope effect, engineering, symbols, General Materials Science, Raman spectroscopy, Helium
Abstract

The pressure responses of portlandite and the isotope effect on the phase transition were investigated at room temperature from single-crystal Raman and IR spectra and from powder X-ray diffraction using diamond anvil cells under quasi-hydrostatic conditions in a helium pressure-transmitting medium. Phase transformation and subsequent peak broadening (partial amorphization) observed from the Raman and IR spectra of Ca(OH)2 occurred at lower pressures than those of Ca(OD)2. In contrast, no isotope effect was found on the volume and axial compressions observed from powder X-ray diffraction patterns. X-ray diffraction lines attributable to the high-pressure phase remained up to 28.5 GPa, suggesting no total amorphization in a helium pressure medium within the examined pressure region. These results suggest that the H–D isotope effect is engendered in the local environment surrounding H(D) atoms. Moreover, the ratio of sample-to-methanol–ethanol pressure medium (i.e., packing density) in the sample chamber had a significant effect on the increase in the half widths of the diffraction lines, even at pressures below the hydrostatic limit of the pressure medium.

Published
2011
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12. Environmental equipment cost analysis: optimum size of a biocoal briquette machine

Author

Kanji Yoshioka, Satoshi Nakano, and Takanobu Nakajima

Subjects
Economics and Econometrics, Briquette, Primary energy, Natural resource economics, business.industry, Biomass, Management, Monitoring, Policy and Law, engineering.material, Torrefaction, engineering, Cost analysis, Production (economics), Environmental science, Coal, Process engineering, business, Lime
Abstract

For developing countries that consume coal as their primary energy source, the method of desulfurization is a major issue. We installed experimental biocoal briquette production machines as a simple, inexpensive technology for desulfurization in China. Biocoal briquettes are a high-pressured mixture of powdered coal and biomass, with powdered lime added as a desulfurizer. In order to spread the use of these machines, it is important to consider the market size and with that knowledge determine the size of biocoal briquette machines. The objective of this study was to quantitatively evaluate the optimum size of biocoal briquette machines. There are two principal effects of economies of scale that need to be considered when evaluating briquette machine size with respect to market size. One effect is that the average marginal briquette cost decreases as the machine size increases. The other consideration is the mass production effect of manufacturing a large number of machines. As a result, below a given market size we should manufacture more machines that have a capacity less than 15t/h, which is the optimum machine size for briquette cost.

Published
2005
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13. Expression of an endoplasmic reticulum-resident chaperone, glucose-regulated stress protein 78, in the spinal cord of a mouse model of amyotrophic lateral sclerosis

Author

Jianhua Zhang, Satoshi Nakano, Shizuo Ohnishi, Reika Wate, Hirofumi Kusaka, and Hidefumi Ito

Subjects
Male, Pathology, medicine.medical_specialty, SOD1, Mice, Transgenic, Polymerase Chain Reaction, Pathology and Forensic Medicine, Pathogenesis, Mice, Cellular and Molecular Neuroscience, Superoxide Dismutase-1, Heat shock protein, medicine, Animals, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, biology, Superoxide Dismutase, Endoplasmic reticulum, Amyotrophic Lateral Sclerosis, Spinal cord, Immunohistochemistry, Disease Models, Animal, medicine.anatomical_structure, Spinal Cord, Cytoplasm, Chaperone (protein), Hyaline inclusion, biology.protein, Female, Neurology (clinical), Molecular Chaperones
Abstract

The immunohistochemical localization of glucose-regulated protein 78/BiP (GRP78), a chaperone protein that primarily resides within the lumen of the endoplasmic reticulum, was investigated in the lumbar spinal cord of mutant copper/zinc superoxide dismutase (SOD1) transgenic mice. Re-staining techniques were used to determine the immunoreactivity with anti-GRP78 antibody of abnormal structures observed by hematoxylin and eosin staining. Besides its physiological localization in the neuronal and glial cytoplasm, GRP78 was expressed in Lewy body-like hyaline inclusions, in irregularly-shaped eosinophilic structures without an apparent halo, and in cord-like swollen neurites. These different sites were invariably also immunopositive for ubiquitin, suggesting them to be pathological structures. The topographic distribution of GRP78 expression closely resembled that of SOD1. Moreover, our chronological quantitative analysis demonstrated that virtually all the Lewy body-like hyaline inclusions were immunolabeled by the anti-GRP78 antibody, irrespective to the age of mice examined, even at the presymptomatic stages. These findings imply that GRP78 may bind to, or at least be closely associated with, SOD1, and may participate in the pathological processes leading to inclusion formation. Thus, the results suggest that dysfunction of GRP78 and subsequent derangement of the system responding to unfolded proteins may be involved in the pathogenesis of familial amyotrophic lateral sclerosis caused by a mutation of the human SOD1 gene.

Published
2005
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14. Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant

Author

Hirofumi Yamashita, Takashi Ayaki, Hirofumi Kusaka, Takeshi Inoue, Masafumi Ihara, Takayuki Kondo, Takuji Fujita, Akemi Shodai, Hiroyuki Morino, Takeshi Asano, Satoshi Nakano, Riki Matsumoto, Makoto Urushitani, Ryosuke Takahashi, Hideshi Kawakami, Satoshi Fukui, Hidefumi Ito, Akito Ikemoto, Jun Kawamata, and Hiroko Fukushima

Subjects
Adult, Male, Pathology, medicine.medical_specialty, Valosin-containing protein, Mutant, Cell Cycle Proteins, Inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD), medicine.disease_cause, Inclusion bodies, Valosin-containing protein (VCP), Pathology and Forensic Medicine, TAR DNA-binding protein 43 kDa (TDP-43), Cellular and Molecular Neuroscience, Valosin Containing Protein, Cell Line, Tumor, medicine, Humans, Amyotrophic lateral sclerosis, Myopathy, Aged, Optineurin, Adenosine Triphosphatases, Aged, 80 and over, Mutation, biology, business.industry, Research, Amyotrophic Lateral Sclerosis, Neurodegeneration, Brain, Middle Aged, medicine.disease, HEK293 Cells, Spinal Cord, Paget disease of bone, biology.protein, Golgi apparatus fragmentation, Female, Neurology (clinical), medicine.symptom, business
Abstract

Background Mutations in the valosin-containing protein (VCP) gene were first found to cause inclusion- body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD). Mutations in the VCP gene were later reported to occur in familial amyotrophic lateral sclerosis (ALS). But the role of VCP in the neurodegenerative processes that occur in ALS remains unknown. The purpose of the present study was to elucidate the role of VCP in the neurodegeneration seen in sporadic and VCP mutant ALS. Results Immunohistochemistry demonstrated that the frequency of distinct VCP-positive nuclei of spinal motor neurons of patients with sporadic ALS (SALS) and the ALS with VCP novel mutation (ALS-VCP, M158V) was increased, compared with that of the control cases. No VCP-positive inclusion bodies were observed in SALS patients, a ALS-VCP patient or in control subjects. Neuropathologic examination of the ALS-VCP case showed loss of motor neurons, the presence of Bunina bodies, and degeneration of the corticospinal tracts. Bunina bodies detected in this case were confirmed to show immunohistochemical and ultrastructural features similar to those previously described. Furthermore, neuronal intracytoplasmic inclusions immunopositive for TAR DNA-binding protein 43 kDa (TDP-43), phosphorylated TDP-43, ubiquitin (Ub), p62, and optineurin were identified in the spinal and medullary motoneurons, but not in the neocortex. Gene analysis of this ALS-VCP patient confirmed the de novo mutation of M158V, which was not found in control cases; and bioinformatics using several in silico analyses showed possible damage to the structure of VCP. Immunocytochemical study of cultured cells showed increased cytoplasmic translocation of TDP-43 in cells transfected with several mutant VCP including our patient’s compared with wild-type VCP. Conclusion These findings support the idea that VCP is associated with the pathomechanism of SALS and familial ALS with a VCP mutation, presumably acting through a dominant-negative mechanism. Electronic supplementary material The online version of this article (doi:10.1186/s40478-014-0172-0) contains supplementary material, which is available to authorized users.

Published
2014
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15. [Untitled]

Author

Tetsuo Hayakawa, Hidenori Toyoda, Takashi Kumada, Yoshihide Fukuda, Junki Takamatsu, Hidehiko Saito, and Satoshi Nakano

Subjects
Hepatitis, medicine.medical_specialty, biology, Physiology, Hepatitis C virus, Hepacivirus, Gastroenterology, virus diseases, Hepatology, biology.organism_classification, medicine.disease, medicine.disease_cause, Virology, digestive system diseases, Virus, Hypervariable region, Flaviviridae, Internal medicine, medicine, Viral disease, human activities
Abstract

We evaluated the sequence diversity of thehypervariable region 1 (HVR1) of hepatitis C virus (HCV)in HCV-infected patients in whom the mode oftransmission is unknown. The sequence diversity of HVR1in 26 Japanese patients with chronic HCV infectionof unknown mode of transmission (UT) was compared with17 patients with chronic posttransfusion hepatitis C inwhom only a single HCV infection had occurred (PH), and with 18 patients with hemophilia withchronic HCV infection who might have been multiplyinfected with HCV (HE). The diversity of HVR1 wasevaluated by direct sequencing after PCR amplification of HVR1. The sequence diversity of HVR1 was10.1 ± 7.7% in UT, 2.7 ± 2.8% in PH, and14.6 ± 6.9% in HE. The diversity of the patientswith unknown transmission was greater than that of theposttransfusion hepatitis patients, and in some patients it wassimilar to that of multitransfused hemophiliac patients(UT vs PH, P = 0.0004; UT vs HE, P = 0.04; and HE vs PH,P < 0.0001). Multiple infections with HCV could have occurred frequently in patientswith chronic HCV infection in whom the mode oftransmission was unknown, which increased the sequencediversity of HVR1 of these patients.

Published
1999
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16. [Untitled]

Author

Masa Karasu, Jun-ichi Kadokawa, Sumikazu Ogata, Satoshi Nakano, Hideyuki Tagaya, and Koji Chiba

Subjects
chemistry.chemical_compound, Azo compound, Dehydration reaction, chemistry, Aluminium, Inorganic chemistry, Intercalation (chemistry), Surface modification, Hydroxide, chemistry.chemical_element, Thermal treatment, Isomerization
Abstract

The inner surfaces of inorganic layered compounds such as aluminium dihydrogen-triphosphate (ADHP) and layered double hydroxide (LDH) were modified by azo compounds. Upon intercalation of 4-phenylazoaniline and 4,4′-azodianiline into ADHP, the interlayer spacing increased from 6.4 to 21.5 A and 20.6 A, respectively. The intensity of IR peaks due to P-–OH of ADHP and amino groups of guests decreased by the thermal treatment of the intercalates. The interlayer spacings also decreased to 16.9 A and 16.7 A, respectively, indicating a dehydration reaction between P–-OH and amino groups. The LDH inner surface was modified by the reaction with trans-p-phenylazobenzoylchloride (PAB-Cl). Upon surface modification, the interlayer spacing increased from 7.6 A to about 27 A. The absorption of this surface-modified LDH near 410 nm increased upon irradiation with UV light and decreased upon irradation with visible light, indicating the occurrence of trans–cis isomerization of PAB-Cl between the layers.

Published
1998
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17. p35 nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease

Author

Satoshi Nakano, Ichiro Akiguchi, S. Nakamura, Jun Kimura, and Yasuhiro Kawamoto

Subjects
medicine.medical_specialty, Parkinson's disease, Blotting, Western, Nerve Tissue Proteins, Substantia nigra, Protein Serine-Threonine Kinases, Biology, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Internal medicine, medicine, Humans, Aged, Brain Chemistry, Staining and Labeling, Lewy body, Kinase, Cyclin-dependent kinase 5, Locus Ceruleus, Brain, Colocalization, Cyclin-Dependent Kinase 5, Parkinson Disease, medicine.disease, Immunohistochemistry, Molecular biology, Axons, Cyclin-Dependent Kinases, Endocrinology, nervous system, Locus coeruleus, Lewy Bodies, Locus Coeruleus, Neurology (clinical)
Abstract

We examined the immunohistochemical localization of p35nck5a, the regulatory subunit of cyclin-dependent kinase 5 (cdk5), in brains obtained postmortem from patients with Parkinson's disease (PD) and controls. We found p35nck5a immunoreactivity in Lewy bodies (LB) in the substantia nigra, locus ceruleus, and neocortex of brains from patients with PD. In addition, p35nck5a was colocalized with cdk5 immunoreactivity in LB. Cdk5 is the kinase most likely to be responsible for the phosphorylation of neurofilament proteins of LB, which is a crucial step for the formation of the insoluble LB fibrils. Since p35nck5a regulates the catalytic activity of cdk5 by forming a heterodimer with cdk5, the present results strongly support the hypothesis that a cdk5-p35nck5a complex is involved in the formation of LB fibrils.

Published
1997
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18. Recovery of portal blood flow after percutaneous transhepatic biliary drainage in patients with obstructive jaundice

Author

Suguru Kumada, Shigehiko Shionoya, Akihiro Yasui, Hiroshi Kanda, Yuji Nimura, and Satoshi Nakano

Subjects
Male, medicine.medical_specialty, Ultrasonic doppler, Gastroenterology, Serum bilirubin, Internal medicine, medicine, Humans, In patient, Prospective Studies, Aged, Aged, 80 and over, Cholestasis, business.industry, Bilirubin, Ultrasonography, Doppler, General Medicine, Middle Aged, Rate of increase, Portal System, Liver, Regional Blood Flow, Portal blood, Drainage, Female, Surgery, Obstructive jaundice, Percutaneous transhepatic biliary drainage, Liver function, business
Abstract

Using an ultrasonic Doppler system, we prospectively studied the changes in portal venous flow (PVF) following percutaneous transhepatic biliary drainage (PTBD) and evaluated the correlation between PVF and liver function in 10 patients with obstructive jaundice. The patients were divided into two groups according to their rate of decrease in serum bilirubin (“b”). Group A comprised 5 patients with a “b” of less than −0.1, while group B consisted of 5 patients who did not meet this criterion. The mean PVF increased following PTBD (P

Published
1997
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19. Anti-deterioration Effect of Lignin as an Ultraviolet Absorbent in Polypropylene and Polyethylene

Author

Hidekatsu Yokoyama, Kiichi Gotoh, Satoshi Nakano, Kazuko Toh, Hiroyuki Noda, and Kenichi Ebe

Subjects
Polypropylene, Polymers and Plastics, Phenylpropanoid, Polyethylene, engineering.material, medicine.disease_cause, Pulp and paper industry, Polyolefin, chemistry.chemical_compound, chemistry, Materials Chemistry, medicine, engineering, Organic chemistry, Lignin, Biopolymer, Cellulose, Ultraviolet
Abstract

A large quantity of plant wastes (such as wood scrap, rice bran, used tea leaves, and the dregs from squeezed fruit) is generated by the woodworking and food industries and agriculture. The recycling of these wastes is limited to their use in feed, fertilizer, fuel, and cosmetics. In this study, by using lignin that is one of the main components in plants, a new recycling method for plant wastes was designed. Lignin is a phenolic high-molecular-mass biopolymer based on phenylpropanoid units that are unique to vascular land plants. It accounts for approximately one-third of the organic matrix of wood and makes up a large component of grasses, leaves, and coniferous tree needles. It is known that lignin absorbs ultraviolet rays well in the wood components. Hirabayashi and Shimizu developed the lignocellulose film which was made from lignin and cellulose and showed high absorption of ultraviolet rays. The lignocellulose is an ultraviolet rays absorption filter. However, it is not clear whether lignin defends matrix in the film from deterioration caused by the ultraviolet rays. In this study, the effect of lignin in synthetic polymer was examined. The influence of lignin as an ultraviolet absorbent to the synthetic polymer as a matrix is now under way. Polypropylene (PP) and polyethylene (PE), popular polyolefin resin plastics in many fields, are commonly used together with an ultraviolet absorbent because tolerance of these plastics to ultraviolet rays is relatively low. Usually, the synthetic ultraviolet absorbent, benzotoriazole or benzophenone series was used for this purpose. It is feared that the use of synthetic ultraviolet rays absorbent such as benzotoriazole affects the environmental status. Use of lignin may decrease the load to the environment because lignin is one of natural materials. Furthermore, it can contribute effective use of botanical wastes. In this study, PP and PE test pieces containing lignin were fabricated, and the anti-deterioration effect of lignin as an ultraviolet absorbent was investigated through an outdoor exposure test. In our knowledge, this is the first report to use lignin as an ultraviolet rays absorbent in the polyolefin resins.

Published
2005
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20. Abstracts of selected papers presented at the 33rd annual meeting of the japanese society of gastroenterology

Author

Shoji Kubo, Hiroaki Kinoshita, Hidekazu Mukai, Masatsugu Nakajima, Akira Kamei, Yuji Horiguchi, Jinkan Sai, Jo Ariyama, Shigehiro Shiraki, Toshihiko Takeuchi, Minoru Hamada, Nobuyasu Ito, Eiji Komatsu, Yoshinori Isobe, Kenji Sakata, Hiroshi Yoshida, Shinichi Kiso, Sumio Kawata, Tsuyoshi Tominaga, Kiyoaki Ohuchi, A. Nemoto, R. Mizumoto, Takafumi Tsunoda, Yoshiro Nitta, Kwang Choon Lee, Osamu Yamazaki, K. Koike, K. Kobayashi, Tetsuji Suyama, Fumiyo Tsubai, Hiromasa Kashimura, Akira Nakahara, Shuji Takahashi, Toshikazu Yoshikawa, Shin Ajitsu, Hiroaki Takeda, Etsuo Hoshino, Umeda Noritsugu, Kazuaki Sasaki, Koichi Hirata, Satoshi Mochida, Kenji Fujiwara, Masayoshi Yamashiki, Akira Nishimura, Hiroshi Yamauchi, Hiromasa Ishii, Hitoshi Ookubo, Yasuyuki Arakawa, Hiroko Oka, Sukeo Yamamoto, Naoki Aihara, Susumu Tazuma, Shuichi Mizuno, Itaru Hasegawa, Yasuhiro Mizoguchi, Kenzo Kobayashi, Masaki Asaka, Makoto Ozaki, Norimitsu Kurihara, R. Kakehashi, J. Ikoma, Hiromi Tokumura, Takashi Matsushiro, Naoto Kanemaki, Kazumu Okushima, Nagao Shinagawa, Jiro Yura, Kose Segawa, Takashi Suzuki, Hiroyuki Hirano, Masaru Koizumi, Satoru Miura, Taizo Shiraishi, Masatoshi Tanaka, Kyuichi Tanikawa, J. Shibata, S. Fujiyama, Shinichi Matsuoka, Junichi Uchino, Eisuke Kawamura, Eizo Okamoto, Yukio Kamimoto, Seiki Tashiro, Jiro Nagaiwa, Hisafumi Kinoshita, Toshimichi Nakayama, Masato Kayahara, Takukazu Nagakawa, Terumi Kamisawa, Tomoaki Isawa, Takashi Hatori, Toshihide Imaizumi, Mitsuhiro Yata, Hirofumi Miyoshi, Shinnichi Furuya, Junpei Takaaki, Masayuki Higashino, Yasumasa Niwa, Junji Yoshino, Takao Wakabayashi, Ken Haruma, Shinya Kishimoto, Sunao Kawano, Hideyuki Fusamoto, K. Higuchi, T. Arakawa, Hideyuki Yoshioka, Tom Kita, Yushi Taniguchi, Ken Kimura, Akira Irie, Atsushi Toyonaga, Masahiro Okuno, Teruyuki Ikehara, Kyotaro Kanazawa, Yukiyoshi Ezaki, Kyohei Maruyama, Shin-ichiro Fukuda, Shinji Horj, Masamichi Satomi, Satoru Iwane, Akihiro Munakata, Shigekazu Hayashi, Akira Arakawa, Fumihiko Inoue, Hiroo Furukawa, Hiroshi Kasugai, Shigeru Okuda, Satoshi Saitoh, Hiromitsu Kumada, S. Takashima, K. Nakamura, Satoshi Kokura, Shuichi Okada, Nobuo Okazaki, Masaharu Yoshikawa, Masaaki Ebara, Hideo Okabe, Satoshi Nakano, Takeshi Urabe, Masashi Unoura, Kenichi Kobayashi, Yoshinori Aoki, Kyuich Tanikawa, Masatoshi Okazaki, Hideyuki Higashihara, Toru Nagashima, Kaichi Isono, Masakazu Ueda, Toshiharu Tsuzuki, Yo Sasaki, Shingi Imaoka, Tohru Kakazu, Masatoshi Makuuchi, Tadatoshi Takayama, Tomoo Kosuge, and Naoki Yamanaka

Subjects
Gastroenterology
Published
1993
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21. Effects of interferon-? on serum hepatitis C virus in patients with chronic hepatitis C

Author

Tsuneo Morishima, Satoshi Nakano, Masahiko Yamada, Toyoichiro Kudo, Takashi Kumada, and Motohiro Shibata

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, Physiology, Hepatitis C virus, Alpha interferon, Hepacivirus, medicine.disease_cause, Polymerase Chain Reaction, Virus, Recurrence, Interferon, Internal medicine, medicine, Humans, Interferon alfa, business.industry, Gastroenterology, Interferon-alpha, virus diseases, Alanine Transaminase, DNA, Middle Aged, Hepatology, Hepatitis C, digestive system diseases, Blotting, Southern, Titer, Chronic Disease, DNA, Viral, Immunology, Drug Evaluation, Female, Viral disease, business, Follow-Up Studies, medicine.drug
Abstract

Interferon is beneficial in some patients with chronic hepatitis C. To assess the efficacy of interferon, we used the polymerase chain reaction (PCR) to measure HCV RNA in serial serum samples from 13 chronic hepatitis C patients who were treated with interferon-alpha. Serum alanine aminotransferase (ALT) values normalized in association with the disappearance of serum HCV RNA in nine cases during the therapy. Serum HCV remained negative after the therapy in the three patients who had no relapse, while serum HCV RNA reappeared in the six patients with elevation of ALT values. The persistence of normal ALT levels appears to be correlated with the clearance of the serum HCV. There were two patients whose ALT became normal immediately after the cessation of interferon. Serum HCV was detectable at the end of treatment when serum ALT was elevated, and thereafter serum HCV disappeared. This result suggests an immunomodulatory effect of interferon in the clearance of HCV in some cases. Furthermore, the semiquantitative PCR assay showed that all five patients in whom ALT values were normal at the end of follow-up without detectable serum HCV genome had lower HCV titers in the pretreatment sera than the other eight patients. The detection of HCV RNA by the PCR assay is useful in determining the efficacy of interferon and its mechanisms.

Published
1993
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22. Abstracts of Selected Papers Presented at the 31st Annual Meeting of the Japanese Society of Gastroenterology

Author

Eii Karasawa, Hiromitsu Saisho, Hiroyuki Maguchi, Tsuyoshi Obara, Keizo Saeki, Tadashi Yamasuji, Kenji Nishihara, Takasi Suzuki, Hisato Tajiri, Hideo Ozaki, D. Fujii, M. Suyama, Masatoshi Mogaki, Hideki Fujii, Toshio Yamamoto, Shuji Isaji, Tohru Itoh, Yasuo Idezuki, Nobuo Baba, Tadao Manabe, Toshihide Imaizumi, Fujio Hanyu, Naoaki Tanno, Jin Ishizuka, F. Yamamoto, H. Igimi, S. Yamamoto, H. Shimura, Tetsuo Takayama, Aiji Noda, Nobuto Hirata, Ken Kadowaki, Yasuyuki Yazaki, Masayoshi Namiki, Hideo Yamada, Teruo Kouzu, Kazuo Ichikawa, Masafumi Ichikawa, Hideichi Seki, Ken Kimura, Takashi Matsushiro, Hisashi Yamaguchi, Rin Yamagata, Toshiyuki Fujio, Masato Furukawa, Sumio Kawata, Yasuharu Imai, Yoshiki Amuro, Kei Kudo, H. Nishimura, K. Akiyama, Koushou Tsukahara, Kenichi Kitani, K. Katagiri, T. Nakai, Norihito Watanabe, Masaya Oda, Hajime Takikawa, Masami Yamanaka, Shotaro Sakisaka, Kyuichi Tanikawa, T. Kakazu, Naomi Tanaka, Junichi Shoda, Susumu Tazuma, Goro Kajiyama, Kazuo Chijiiwa, Fumio Nakayama, Yutaka Hikasa, Noritoshi Tanida, Tomio Narisawa, Masahiro Takahashi, Masahiro Tanaka, Haruki Matsumoto, Koichi Kojima, Isao Takeda, Satoshi Nakano, Yasubumi Shiina, Shigeru Harasawa, Shuji Okuyama, Hisato Hara, Mitsuya Iwafuchi, Hidenobu Watanabe, H. Morizumi, M. Matsumura, Akira Sato, Shigeru Asaki, Yoshio Hosokawa, and Masanori Hirao

Subjects
Gastroenterology
Published
1991
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23. Abstracts Of Selected Papers Presented At The 75Th General Meeting Of The Japanese Society Of Gastroenterology March 27–29, 1989 — Yokohama, Japan

Author

Satoshi Tanabe, Katsunori Saigenji, Shigeru Asaki, Akira Sato, Isao Takeda, Satoshi Nakano, Yoshihiro Inoue, Atsushi Kano, Yasubumi Shiina, Takeshi Miwa, Hiroshi Takahashi, Kimio Namatame, C. Sugawa, R. Nakamura, Hideichi Uchida, Tadashi Kodama, Shinji Oka, Yukinori Okazaki, Nobuhiro Sato, Tatsuo Ogihara, Yasumasa Niwa, Saburo Nakazawa, Yoshiteru Azuumi, Yutaka Saito, Kunio Sato, Ariyoshi Iwasaki, Masanao Abe, Mamoru Miyairi, Kyoichiro Suyama, Tetsuo Hayakawa, Toshiyuki Suzuki, Hirofumi Miyake, Koji Ochi, Hideyuki Wakasugi, Akihiro Funakoshi, Keiichi Sugiyama, Tadao Manabe, Nobuo Baba, Masahiro Yamamoto, Yoichi Saitoh, Kazutami Tamura, Yoshihiro Fukuda, Nobuhiro Sakaki, Katsuyuki Ietomi, Masahiro Yamada, Toshifumi Ohkusa, Shinichi Takahashi, Shozo Saito, Kiichi Satoh, Ken Kimura, Shigeji Ito, Yoshihiro Kohli, S. Koyama, T. Bamba, A. Takagi, K. Kojima, T. Sugiyama, T. Yabana, Masahiro Tada, Masaki Shigeeda, M. Yoshida, I. Imoto, Takafumi Hashiguchi, Tadashi Shibue, Hiroshi Saita, Motonobu Murakami, Masahiko Tsujii, Sunao Kawano, Takayuki Shirai, Shigeru Harasawa, Tomikazu Yamamoto, Akiyoshi Nishio, Susumu Saeki, Toumei Oh, Masaharu Tatsuta, Hiroyasu Ishii, Hideki Nishiwaki, Katsusuke Satake, Yasushi Matsuzaki, Naomi Tanaka, Akira Knakano, Tsuneo Fukushima, I. Horiuchi, G. Kajiyama, Hideaki Saito, Yasuhiko Morioka, Soichiro Miura, Masahiro Yoshioka, and Naomi Takahashi

Subjects
Gastroenterology
Published
1991
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24. Abstracts of selected papers presented at the 30th Annual Meeting of the Japanese Society of Gastroenterology October 20–22, 1988 — Kagoshima, Japan

Author

Ichiro Oda, Kaoru Ogawa, Shuichi Okada, Keiichi Ueno, Tohru Itoh, Yuji Horiguchi, Hiroshi Kijima, Kazuo Inui, Akitoshi Koga, Tetsuro Hamamoto, Hideaki Tsukada, Takashi Tamada, Takahiko Nakamura, T. Okanoue, Daisuke Koike, Hirohiko Abe, Tsutomu Miura, Shuji Hashimoto, M. Oda, T. Azuma, Shigeyuki Nagata, Hiromasa Ishii, Norifumi Kawada, Yasuhiro Mizoguchi, Yuji Yoshikawa, Hiroshi Oka, Takafumi Ichida, Fumihiro Ichida, Takato Ueno, Kyuichi Tanikawa, Norihiro Kokudo, Seiji Kawasaki, Morikazu Onji, Hiroaki Miyaoka, Osamu Yokosuka, Masao Omata, Hiroshi Ikeda, Takao Tsuji, Shigeki Hayashi, Kenji Fujiwara, Mitsuru Yasunaga, Kiwamu Okita, Koujirou Takase, Yukihiko Tameda, Hiroo Ohnishi, Jun-ichi Sugihara, Hideo Kojima, Tomoteru Kamimura, Eiji Tanaka, Hidetoshi Yoda, Atsushi Kanno, Masao Ohtsuki, Yasuji Miyata, Shunichi Koga, Masashi Unoura, Nobuyoshi Tanaka, Takahiro Kodama, Hideo Nishimura, Kazuyuki Suzuki, Takeo Madarame, Masafumi Komatsu, Shunji Ookubo, Masataka Nishiyama, Shozo Saito, Ryukichi Kumashiro, Kenji Ikeda, Hiromitsu Kumada, Shuhei Nishiguchi, Tetsuo Kuroki, Makoto Yoshiba, Yukari Takeuchi, Takao Morito, Reiji Kasukawa, Isao Takeda, Satoshi Nakano, Kenzo Matsumura, Tomohiro Imanari, Shigeki Lee, Naotaka Fujita, Tetsuya Mine, Eiichi Sato, Masafumi Suyama, Jo Ariyama, Toshihisa Takahashi, Masanori Hirano, Atsushi Hirai, Tatsuo Yamakawa, Junichi Kamiya, Yuji Nimura, Hideo Yoshimoto, Seiyo Ikeda, Tadashi Yamasuji, Keizo Saeki, Masaki Itoh, Goro Kajiyama, Hideichi Seki, Ken Kimura, Hiroshi Nakamura, Yukihiro Tsuchiya, Ryosuke Omura, Shinya Tanaka, Katsuhide Shimakura, Yoshiaki Matsuda, Tokio Wakabayashi, Hideo Morimoto, Yasutaka Kamiya, Yasutaka Okayama, Masao Kobayashl, Sotaro Fujimoto, Atsumasa Yamaguchi, Tadashi Shibue, Ryukichi Akashi, Masahiro Hattori, Yasunori Takehira, Yasutoshi Tsugane, Yoshinori Tashiro, Hajime Kuwayama, Yoichi Kon, Tsugio Higuchi, Nobuto Hirata, Tomoyuki Kano, Kumiko Kurimoto, Y. Kubota, T. Seki, Yoshimine Kamura, Toshimichi Nakayama, Hitoshi Yoshimura, Tetsuya Yoshioka, Kimihiko Akimoto, Hirohide Ohnishi, Etsuro Ogata, Atsushi Igarashi, Atsushi Kadowaki, Tsutomu Yaoita, Naoki Sato, Kimitsune Monma, Hiroaki Kogure, Yoshio Tajima, Hideki Takanashi, Kazuo Haniya, Masao Ohto, Ikuo Murata, Takashi Tanaka, Takashi Sakabe, Takashi Kato, Tadashi Koike, Tetsuya Watanabe, Tetsuo Nakamura, H. Kato, I. Ikai, N. Nishimura, N. Kobayashi, K. Ozawa, Katsuyuki Ono, Michio Sata, Ken Kadowaki, Jiro Ikoma, Yuji Kojima, Tetsuya Murata, Ryuichi Kakehashi, Toshio Ibe, Uichiro Kano, Tetsuo Ito, Takeshi Tanaka, Shozo Watanabe, Shiro Suzuki, Osamu Nakazawa, Kyuhei Kohda, Kohzo Ohyama, Shoki Terada, Katsuhiko Sazaki, Teikichi Kure, Koetsu Morita, Osamu Shida, Hiroshi Muramatsu, Yoshiro Niitsu, Shinichi Tozuka, Yoshinori Sakai, Takaaki Ikeda, Wataru Koyama, Shigemi Sakamoto, Masaaki Kanayama, Naohide Tanaka, Yasuyuki Arakawa, Yutaka Matsuo, Kouichi Takaguchi, Gotaro Yamada, Kazuharu Matsuura, Hirosi Ikeda, Yoshiaki Iwasaki, Kazuhiro Nouso, Kazuhiro Matsueda, Masahiko Sawahara, Shigeatsu Fujiki, Motowo Mizuno, Shingo Kino Yama, Seijin Nadano, Norio Horiike, Kojiro Michitaka, Izumi Kumon, Yasushi Ogawa, Shuji Yamaguchi, Yasuyuki Ohta, Masaaki Nishi, Yasushi Matsuzaki, Naomi Tanaka, Hisashi Matsumoto, Yoshimichi Chuganji, Toshiaki Osuga, S. Shoji, M. Kurata, M. Wakashima, Y. Itoh, M. Hagiri, T. Kondou, M. Katayama, K. Nishizawa, H. Takikawa, H. Ohsawa, M. Miyake, M. Yamanaka, Teruji Ooka, Masahiko Akita, Hogen Kim, Michio Kato, Manabu Masuzawa, Takumasa Okuyama, Masahiko Akiyama, Yoshitaka Ishigami, Kazuya Tamura, Osamu Fukui, Hiroshi Abe, Takenobu Kamada, Ken Arai, Michiko Shindo, Tadao Okuno, Masayuki Matsumoto, Makoto Takeda, Tatsuro Takino, Yoshihiro Sokawa, M. Omata, O. Yokosuka, Y. Ito, K. Hosoda, M. Ohto, Yoshinobu Fuse, Tadashi Kodama, Kenji Sugiyama, Shinobu Nakajo, Shin Ajitsu, Tsuneo Takahashi, K. Kuroe, Y. Murata, and Hideo Ikeda

Subjects
Gerontology, medicine.medical_specialty, Surgical oncology, business.industry, Internal medicine, General surgery, Gastroenterology, medicine, Hepatology, business, Colorectal surgery, Abdominal surgery
Published
1990
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25. Panel Discussion: Treatment of acute pancreatitis

Author

Yoichi Saito, Yasushi Toda, Y. Kubota, Toshiya Ito, Isamu Murata, Satoshi Nakano, K. Kubo, Toshishige Wakabayashi, and R. Mizumoto

Subjects
medicine.medical_specialty, business.industry, General surgery, Gastroenterology, Hepatology, medicine.disease, Colorectal surgery, Surgical oncology, Internal medicine, medicine, Acute pancreatitis, business, Abdominal surgery, Panel discussion
Published
1975
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26. Proceedings of the 27th Annual Meeting Matsuyama, Japan, November 7–9, 1985

Author

C. E. Rogler, Yoshihiro Muto, Masayuki Uchimura, Hiroshi Kijima, Hidenobu Watanabe, A. Kakita, M. Kambayashi, T. Takahashi, Y. Saji, T. Tsuburaya, J. Uchino, Yoshifumi Ogura, Hiroshi Yamagiwa, Y. Takehara, K. Yamashita, Seikoh Shimaguchi, Joe Ariyama, Sei Tomatsu, Itaru Oi, Tadasu Fuji, Takayoshi Noguchi, Kenji Yamao, Saburo Nakazawa, H. Suzuki, R. Mizumoto, Masamitu Kumon, Takuro Ogata, Kenichi Yamamoto, Kenichi Sasaki, Hideo Kida, Yuji Nimura, Naokazu Hayakawa, Junichi Kamiya, Shigehiko Shionoya, Yoshinobu Hata, Jun-Ichi Uchino, Takaaki Yamane, Katsutaka Mori, Hiroaki Kinoshita, Tadashi Inoue, Kenichi Takayasu, Noriyuki Moriyama, Masatoshi Makuuchi, Ken Takasaki, Seiichi Tanaka, K. Shirakawa, F. Misaki, Tadashi Shibue, Keizo Tanaka, Masahiro Asaka, Masao Saito, Susumu Yamagata, Yasuo Utiyama, K. Kobayashi, T. Arakawa, Kei Matsueda, Akira Muraoka, Noritsugu Umeda, Shyuzi Mizumachi, Kiwamu Okita, Hiroshi Sakaue, Kouichi Akamatsu, Teruaki Aoki, Fusahiro Nagao, Yozo Watanabe, Tsutomu Kidokoro, Satoshi Nakano, Takashi Kumada, Takaharu Kondo, Tetsuo Hayakawa, Michio Ogawa, Yasuki Matsuda, Takesada Mori, Hideki Yasuda, Yutaka Atomi, Norihito Ohnishi, Akira Kuroda, Yasuhiko Morioka, Katsusuke Satake, Ryoichi Tsuchiya, Shuji Isaji, Ryuji Mizumoto, Masahiro Yamamoto, Yoichi Saitoh, Kazunori Takeda, Susumu Taguchi, Hitoshi Funatomi, Yoshio Hatta, Mikiko Ono, Tatsuya Itoshima, Ryoji Tanaka, Shunichi Sato, Hitoshi Sugaya, Shunji Futagawa, Kenichi Kobayashi, Hironaka Kawasaki, Hirotada Ohkubo, Yoshifumi Kawarada, Hiroyuki Hirasawa, Michio Odaka, Kaichi Isono, Soichiro Miura, Yoshiki Hamada, Tadao Bamba, Nobuo Chikamochi, R. Nezu, A. Okada, Masahiro Okuno, Kaoru Umeyama, Nobuo Hiwatashi, Kazuyuki Nakajima, Tadahiko Fuchigami, Tsuneyoshi Yao, Masakazu Takazoe, Ryosuke Shoda, T. Fukushima, M. Kawamoto, Kenji Mizutani, Katsuhiko Nakai, Katsunori Aoki, Satoru Morioka, Shozo Baba, Akio Sakamoto, Sadahito Usui, Yoshihiro Fukuda, Kazutami Tamura, Hikaru Watanabe, Takato Ueno, Kyuichi Tanikawa, Masaya Oda, Toshio Morizane, Hiroyuki Hashimoto, Ichiro Shimizu, Kenji Shima, Kohsuke Sasaki, Toshimitsu Suzuki, Yoshifumi Seto, Toshiaki Nakashima, Kendo Kiyosawa, Haruhiko Imai, Yukihiro Shimizu, Hiroshi Sasaki, Teruo Mori, Yoshio Mori, Makoto Ogawa, Masafumi Wakashin, Kunio Okuda, Chiaki Kawamoto, Kenichi Ido, Kiyotaka Fujise, Seishi Nagamori, Shinichiro Fujikura, Kazuhiko Shimada, Kazuhito Yamaguchi, Yoshinori Fujimura, Tsuyoshi Kihara, Hironobu Kitamura, Yoshihide Fujiyama, Hitoshi Asakura, Kensuke Kobayashi, Hiroshi Nagura, Takashi Koshikawa, Yuji Murata, Kiyoo Kuroe, H. Kawanishi, K. Koyama, S. Senda, J. Kiely, Kazuo Harima, Masato Furukawa, Toshinori Nakata, Hiroyuki Kawahara, Nobuhiko Komi, Yukio Ishihara, Satoshi Kondo, Koichi Suda, Takeshi Miyano, Kazuo Inui, Toshikazu Ohnuma, Noboru Yamamichi, Fumio Konishi, Nobuto Morita, Yutaka Tanikawa, Eiichi Kitani, Toshikazu Tamura, Tetsuo Ohta, Kohji Konishi, Makoto Utsumi, Noriyuki Ueda, Hideto Sasaki, Toshio Kawamoto, Itaru Horiuchi, Kouji Tada, Teiko Nakai, Katsuko Yamashita, Fuyuhiko Ninomiya, Yasuo Naito, Keiichi Morita, Hitoshi Hachiya, Toshihiko Takeuchi, Keizo Onuki, Toshihiko Ozaki, Y. Tsuchiya, H. Nakamura, Hideyuki Nagashima, Takashi Matsushiro, Masahiro Nakai, K. Takeuchi, G. Watanabe, T. Ito, Y. Idezuki, Masatoshi Isogai, and Kitao Hachisuka

Subjects
medicine.medical_specialty, Surgical oncology, business.industry, Internal medicine, General surgery, Gastroenterology, medicine, Hepatology, business, Colorectal surgery, Abdominal surgery
Published
1986
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27. Proceedings of the 23rd Autumn Meeting from October 14–16, 1981-Yonago City, Tottori, Japan

Author

Takeshi Hoshi, Toshio Shikata, Emanuel Rubin, Isidore Cohn, Chisato Hirayama, Makizo Hirata, Mitsuru Saito, Masatoshi Sano, Tsutomu Sasagawa, Hiromasa Ishii, Yoko Ebihara, Kazuhiko Okabe, Tohru Takahashi, Fumihiro Ichida, Shoji Yamada, Kazumi Nagasaka, Kazuo Ogura, Masayoshi Yamauchi, Kiyoshi Fujisawa, Tetsuo Hayakawa, Yoshinobu Takeda, Akira Wakabayashi, Akira Kuroda, Kazuhiko Yahata, Isao Ishikawa, Shuichi Akao, Kenji Nakayama, Yasuo Nosaka, Hajime Watahiki, Satoshi Nakano, Sumihiko Okuyama, Tsuguo Inokawa, Isao Marino, Teruo Nakamura, Jiro Yanagisawa, Tadasu Tsujii, Toshiaki Osuga, Hiroshi Tanimura, Fumio Sugata, Akifumi Kobayashi, Hiroyasu Makuuchi, Toshio Mitomi, Kimio Onozawa, Kinichi Nabeya, Toshio Hirashima, Toshifumi Iizuka, Isamu Yamamoto, Goro Yamaki, Teruo Kouzu, Kaichi Isono, Misao Yoshida, Mitsuo Endo, Keizo Sugimachi, Kiyoshi Inokuchi, Akiyoshi Yamada, Yoshioki Hishinuma, Yoshigi Murakami, Tetsuo Morishita, Masaharu Tsuchiya, Tsuyoshi Kida, Tsuyoshi Tajima, Shintaro Miyamoto, Eiyo Yukawa, Kazumichi Harada, Kazuo Mizushima, Masahiro Tada, Yuzuru Kajiwara, Koichi Suzuki, Mitsuo Iida, Akinori Iwashita, Masatoshi Watanabe, Koji Nomura, Yasuhiro Hara, Yösuke Seo, Itaru Oi, Tadahiro Takada, Joe Ariyama, Eii Karasawa, Hiromitsu Saisho, Seiki Matsuno, Yoshiro Ogata, Kenji Kobayashi, Takashi Suzuki, Kunio Takagi, Kyosuke Ushio, Tatsuya Yamada, Shigeo Kobayashi, Keiji Tanaka, and Tsuneyoshi Yao

Subjects
Gerontology, medicine.medical_specialty, Surgical oncology, business.industry, Internal medicine, General surgery, Gastroenterology, medicine, Hepatology, business, Colorectal surgery, Abdominal surgery
Published
1982
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28. Proceedings Of The 21St Autumn Meeting From October 15th-17th, 1979-Maebashi, Japan

Author

Yasuhiro Mizoguchi, Fumiaki Ohnishi, Toshio Morizane, Masaharu Tsuchiya, Masashi Unoura, Yasuhiro Kato, Yoshiro Takazakura, Noriyuki Kitami, Shinichi Kakumu, Tomiji Kashio, Takayoshi Endo, Yoshio Taoka, Reiji Kasukawa, Takao Morito, Gotaro Toda, Hirao Maeda, Masaji Nambu, Toshihiko Namihisa, Masakatsu Matsukawa, Ikuo Tabata, Masatoshi Makuuchi, Yasutsugu Bandai, Yuji Itai, Isao Takeda, Satoshi Nakano, Tatsuo Yamakawa, Fumio Komaki, Masaru Miki, Akiro Shirota, Koichi Shibasaki, Akira Honma, Kyoichi Hiramatsu, Yoshinori Isobe, M. Okazaki, Katsuhiko Sugahara, Nobuhiro Kawano, Susumu Mitani, Nobuya Kintaka, Tetsuaki Mizuta, Eiso Okamoto, Ryuji Mizumoto, Yasuo Endo, Shiro Uno, Eio Atari, Norio Nakamura, Hisaaki Shimazu, Tomio Konishi, Shiro Hayashi, Hideyuki Ichikawa, Haruki Mori, Yutaka Matsuo, Keiji Ohe, Akima Miyoshi, Tsuyoshi Yabana, Akira Yachi, Yukio Nagamachi, Masaki Kitajima, Mitsuhisa Ueda, Satoru Sohma, and Keizo Ishihara

Subjects
medicine.medical_specialty, business.industry, Atrophic gastritis, General surgery, Gastroenterology, Gastric mucosal blood flow, Hepatology, medicine.disease, Colorectal surgery, Surgical oncology, Internal medicine, medicine, business, Abdominal surgery
Published
1980
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29. Proceedings of the 69th General Meeting from April 11–13, 1983-Osaka, Japan

Author

Yoshihiro Baba, Kunio Nagata, Yoshihisa Tsukada, Rintaro Narisawa, Akira Honma, Shinichi Hirose, Mineo Tomizawa, Toshihiko Ozaki, Fumihiro Ichida, Kenji Tanehiro, Nobuyoshi Kuno, Kumiko Kurimoto, Tetsuo Yokota, Tomoyuki Kano, Tatsuzo Kasugai, Kazuya Ueno, Katsuhide Shimakura, Akira Kakita, Masaaki Kambayashi, Tsuyoshi Takahashi, Eisei Sasaki, Yoichi Kasai, Toshihisa Takahashi, S. Shimaguchi, J. Ariyama, Masatoshi Sumida, Yukihiro Tsuchiya, Masao Ohto, Fumio Asagami, Tadasu Fuji, Norimasa Okabe, Kenji Sakurai, Shuichi Miyakawa, Yuji Horiguchi, Hiroshi Nakano, Yuji Nimura, N. Hayakawa, H. Hasegawa, J. Kamiya, S. Maeda, Y. Iyomasa, Yoshiro Matsumoto, Katsuhiko Sugahara, T. Ida, R. Mashimo, Shu Kou Wen, H. Fujii, S. Wakashiro, G. Isowa, S. Itoh, T. Yamakawa, Hidenori Udaka, Hideyuki Miyamoto, Toshikazu Tamura, Tsutomu Hirai, Osamu Okamura, Nobuhiko Komi, Nobuo Yoshioka, Yoshio Kawamura, Takahiko Kojima, Hitoshi Hachiya, Nobuyoshi Okumura, Kunihiko Suzuki, Toshiyuki Suzuki, Sadasuke Suzuki, Norishige Ozeki, Kazuo Goto, Shigehiro Shiraki, Toshihiko Takeuchi, Atsumasa Yamaguchi, Tadashi Shibue, Yukimitsu Kawaura, Takashi Iwa, Isao Takeda, Satoshi Nakano, Tomoko Kobayashi, Hideo Harada, Tokio Wakabayashi, Norio Sawabu, Yasuo Naito, Saburo Nakazawa, Tomoaki Isawa, Ikuo Tabata, Yuichi Sasaki, Hideaki Yamada, Shunichi Tatsumi, Kenzo Kobayashi, Eitaro Suzuki, Eizo Okamoto, Masakatsu Matsukawa, Toshio Nakanishi, Hiroiku Kawakami, Sotaro Fujimoto, Masatsugu Nakajima, Junichi Sugihara, Yoichi Saitoh, Takashi Matsushiro, Hideyuki Nagashima, Kyoji Yamamoto, Ryuji Nakamura, Junichi Tanaka, Fumito Shimizu, Takashi Toshima, Tuneo Hariu, Takukazu Nagakawa, Noriyoshi Suzuki, Wataru Takahashi, Ikunoshin Uematsu, Toshio Sato, K. Egami, T. Tajiri, N. Aoki, K. Yamaguchi, H. Yamakawa, A. Watanabe, M. Yano, S. Hatta, M. Yoshioka, M. Miki, A. Shirota, Koji Morimoto, Masato Furukawa, Toshinori Nakata, Ryuhei Yamada, Shinichiro Ito, Shigeru Maeda, Toshinori Morinaga, Makota Tanigawa, Toshiyuki Fujio, Hiroshi Inui, Hiroaki Kinoshita, Osamu Yamasaki, Eiichi Nagata, Kazuhiro Hirohashi, null Sakai, Tadahiro Takada, Hideki Yasuda, Makoto Shishikura, Katsuhiro Uchiyama, Yoshifumi Ogura, Ryuji Mizumoto, Kazuomi Nakazawa, Shunichi Sato, Isamu Kaito, Hiroshi Suzuki, Masao Ohtsuki, Yoshio Goto, M. Nomoto, K. Yunoue, K. Soga, F. Ichida, Y. Koike, K. Kiyosawa, Y. Akahane, K. Kamijyo, Y. Suzuki, S. Yamamura, T. Komatsu, A. Nagata, S. Furuta, Shigeki Hayashi, Yasuhiko Ohta, Kenji Fujiwara, Yuzuru Sato, Itsuro Ogata, Katsuyoshi Takatsuki, Shunji Mishiro, Hiroshi Oka, Masaru Furube, Nobuo Yamada, Hisao Shibata, Akitaka Shibuya, Eishi Hijikata, Shigenobu Kokubu, Kohdo Ishii, Haruya Okabe, Kenichi Sasaki, Akira Takada, Jugoro Takeuchi, Yasuyuki Ohta, Tadashi Tsujii, Fumiaki Ikegame, Masashi Unoura, Akihiko Furusawa, Nobuyoshi Tanaka, Yasuhiro Kato, Kenichi Kobayashi, Nobu Hattori, Yukihiko Tameda, Satoshi Kakiuchi, Yoshitane Kosaka, Shigeyoshi Harihara, Sukeo Yamamoto, Gotaro Yamada, Hideo Nagashima, Morikazu Onji, Yoshimasa Yamashita, Norio Horiike, Hirohiko Abe, Kazuhiko Hino, Masaru Kojima, Kazunori Noguchi, Hiromu Ueda, Tomoki Aritaka, Naoto Maruyama, Hitoshi Motoori, Kazuaki Yamauchi, Hiroshi Setoyama, Michio Sata, Yasuhiko Kubo, Kyuichi Tanikawa, Tatsuo Munehisa, Keisuke Nakata, Kenzo Kono, Toyoichi Muro, Akira Sato, Ryuji Furukawa, Nobuko Ishii, Yukio Kusumoto, Toshihiko Koji, Shigenobu Nagataki, Norio Nakao, Kohi Miura, Y. Sato, Y. Ohta, I. Ogata, S. Hayashi, K. Fujiwara, H. Oka, S. Furui, M. Iio, Kenji Ikeda, Eiji Oyake, Kazuo Takeuchi, Hiromitsu Kumada, Masao Nakajima, Akira Yoshiba, Masahiro Irimoto, Toshio Kobayashi, Morio Satoh, Ryusaku Yamada, Haruki Nakatsuka, Kenji Hirai, Masanobu Kumagai, Genjiro Yamaguchi, Masatoshi Tanaka, Masanobu Abe, Keijiro Ando, Yasushi Shingai, Kiwamu Okita, Tadayoshi Takemoto, Kazuo Tarao, Kenichiro Iwamura, Kenji Soga, Minoru Nomoto, Hitoshi Takagi, Takafumi Ichida, Shunsaku Higashi, Takashi Noguchi, Takashi Kanematsu, Kenji Takenaka, Takashi Matsumata, Takashi Sonoda, Toshiya Furuta, Keizo Sugimachi, Kiyoshi Inokuchi, Susumu Yamasaki, Hiroshi Hasegawa, Masatoshi Makuuchi, Yoshimi Nakanishi, Hidekazu Sano, Tetsuro Konno, Fumio Sano, Toshiharu Tsuzuki, Shuhei Iida, Naoki Yamanaka, Keiji Kuwata, Akihiro Toyosaka, Nobutaka Tanaka, Shiro Fujiwara, Hajime Yamazaki, Katsuji Sakai, Tokio Ono, Hiroaki Yamada, Masahiro Tada, Hitoshi Asakura, Kensuke Kobayashi, Tetsuo Morishita, Masaharu Tsuchiya, Nobutaka Sato, Hideo Hiratsuka, N. Ueda, and K. Harada

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Gastroenterology, Library science, Medicine, business
Published
1984
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30. Diagnostic ability of hepatobiliary scintigraphy

Author

Isao Takeda, Satoshi Nakano, and Hajime Watahiki

Subjects
medicine.medical_specialty, Gallstones, Scintigraphy, Adenoma, Bile Duct, Cholelithiasis, Surgical oncology, Internal medicine, medicine, Humans, Isoleucine, Biliary Tract, Radionuclide Imaging, Cholangiopancreatography, Endoscopic Retrograde, medicine.diagnostic_test, business.industry, General surgery, Gastroenterology, Technetium, Organotechnetium Compounds, Hepatology, Biliary cancer, Colorectal surgery, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Liver, Radiology, Tomography, X-Ray Computed, business, Abdominal surgery
Abstract

Morphological aspects of biliary images were observed by the hepatobiliary scintigraphy using 99mTc-PI (pyridoxylidene isoleucine). Our study was made mainly on the diagnostic ability of the scintigram in various hepatobiliary diseases. Diagnostic findings were observed in 53.8% of the cases with intrahepatic stones and all cases with cholangioma. In the stone of the common bile duct and extrahepatic biliary cancer, the diagnostic findings were observed in 42.3% and 37.5% respectively. Hepatobiliary scintigraphy was less reliable for the diagnosis of the lesions in the gallbladder. The findings by hepatobiliary scintigraphy were as same as those by X-ray basically. In the cases showing the diagnostic finding by hepatobiliary scintigraphy, it seems to be possible to distinguish the stone from the cancer. Contrary to X-ray picture, scintigram is inferior in the image. So, it is necessary to perform ERCP or PTC to investigate fully the hepatobiliary lesions.

Published
1982
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31. Proceedings of the 26th annual meeting Chiba, Japan, October 18–20, 1984

Author

Shunsaku Higashi, Yoshio Yamazaki, Junji Tanaka, Kazue Ozawa, Munemasa Ryu, Michio Odaka, Kuniaki Kojima, Takashi Hanzawa, Mitsuo Sugiura, Toru Kanno, Sukeo Yamamoto, Keijiro Ando, Yuji Kado, Morio Sato, Ryusaku Yamada, Masaru Miyazaki, Katsuji Okui, Shingi Imaoka, Yo Sasaki, Yoshiyuki Shimamura, Hisakazu Shimizu, Kiyotaka Tezuka, Ichiya Tsuji, Shoji Kajikawa, Masanori Ishii, Akira Takahashi, Toshinori Kodama, Tomomi Kitatani, Tomoharu Matsuyama, Hiroshi Hasegawa, Hiroaki Kawashima, Katsuyoshi Tabuse, Masaharu Katsumi, Kenji Jinno, Katsuyuki Tokuyama, Yasuo Majima, Yasuhiko Kubo, Atsushi Toyonaga, Satoshi Eguchi, Kenji Hirai, Masahide Abe, Haruki Nakatsuka, Sumio Takashima, Yoshihiro Fukuda, Masahiro Hiraoka, Takatoshi Sasaki, Masakazu Maruyama, Mamoru Nishizawa, Kyoichi Nakamura, N. Saitoh, H. Sarashina, Shinei Kudo, Takeyasu Suda, Shu Kuramoto, Takeshi Oohara, Tomio Narisawa, Makoto Niwa, Nobuaki Kaibara, Shigemasa Koga, S. Takashima, T. Kosaka, Kohi Miura, Norio Nakao, Kunio Ido, Kyoichi Hiramatsu, S. Matsutani, K. Kimura, Akira Sano, Yasumasa Kuroda, Kiyohiro Kawahara, Tomoharu Yoshida, Shuzi Mizumachi, Ken Takeuchi, Yukio Kobayashi, Yasuhiro Takase, Tadasu Fuji, Hideo Amano, Akiyoshi Shu, Eizo Okamoto, Hirokazu Kawata, Tomomitsu Kikuchi, Noburu Sakakibara, Morio Masaki, Reiji Kasukawa, Fumiaki Ikegami, Sachio Takasu, Yoshihisa Tsukada, Fumihiro Ichida, Hiroaki Suzuki, Yoshinori Inagaki, Hideki Yasuda, Tadahiro Takada, Toshikazu Suwa, Yutaka Atomi, Yasuhiko Morioka, Tokuyuki Yokohata, Hisaaki Shimazu, Sadamu Takano, Katsunori Yukimura, S. Shimaguchi, J. Ariyama, Satoshi Sawada, Yoshikuni Okamura, Tomohiko Yoshida, Toshihiko Saito, Okitsugu Nishimura, Haruaki Ogawa, Masahiko Morita, Hiromitsu Saisho, Katsuhide Shimakura, Kazuya Ueno, Susumu Miyata, Tadashi Shibue, Atzumasa Yamaguchi, Seiji Tsunoka, Katsuji Hayashi, Yoshihiko Komatsu, Masakatsu Matsukawa, Yasuso Soejima, Y. Nimura, Toshikazu Ohnuma, Kazuo Inui, Takashi Matsushiro, Hideyuki Nagashima, Hideo Ise, Toshio Sato, Y. Akita, S. Shichino, H. Suzuki, T. Sato, K. Ono, Hideki Fujii, Masayuki Yamamoto, Yoshiro Matsumoto, Katsuhiko Sugahara, Tetsuo Ota, Kohji Konishi, Mikiko Ono, Satoru Sohma, Junji Yoshino, Hirosato Ohta, Hiroshi Obata, Tetsuya Ageta, Sumiaki Tsuru, Yutaka Sasagawa, Koichi Yoshida, Toshiaki Jo, Tsuneo Sasaki, Junichi Ishiwata, Jiro Fujimoto, Takesada Mori, Noboru Azuma, Toshiki Kamano, Akeo Hagiwara, Toshio Takahashi, Y. Sasaki, J. Sasaki, Yasuaki Arai, Choichiro Kido, Kyoichiro Suyama, Masatsugu Kitamura, Yasuyuki Awane, Mishio Maeta, Yuzuru Sugiyama, Hiroki Sohma, Toshiaki Nakashima, Yoshihiro Nakagawa, Kazuo Chijiiwa, Masahiro Yamamoto, Yoichi Saitoh, Itaru Horiuchi, Susumu Fujita, Teruo Nakamura, Isao Marino, Yasushi Matsuzaki, Toshiaki Osuga, Yasutoshi Konno, Nobuo Hiwatashi, Noriaki Tamura, Chisato Hirayama, Naoki Ishiguro, M. Tsuchiya, Masahide Ikeguchi, Susumu Tateno, Toshiaki Setoguchi, Yutaka Shimizu, Masahito Tanaka, Kiyoaki Ouchi, Kenji Koyama, Masayuki Saito, Kunihiko Ohnishi, Fuminori Moriyasu, Motohide Takashi, Shinichi Hino, Toru Kashiwagi, Takeo Koizumi, Kazuo Nagayama, Masaharu Horiguchi, Norio Ueno, Takeo Yamanaka, Akitake Hasumi, Haruo Aoki, Hiroaki Takenaka, Kazuyasu Nakao, Osamu Yamazaki, Hiroaki Kinoshita, H. Komatsu, M. Oda, N. Tsukada, K. Kaneko, Y. Shigeta, K. Funatsu, Akiharu Watanabe, Kazuo Tobe, Akira Matsuo, Yukio Kusumoto, Yukihiko Adachi, Toshio Yamamoto, Chikara Oshio, Hiromasa Ishii, Shigeki Matsuki, Hisao Shibata, Tatsuhiko Kodama, Fumimaro Takaku, Yasuji Miyata, Shigeru Sakamoto, Nobutake Matsuo, Yutaka Tsuchiya, Haruki Nakamura, Toshihiro Maruyama, Tomofumi Morita, Tadasu Tsujii, Masayoshi Kage, Masahiro Arakawa, Nobuyuki Sugiura, Masaaki Ebara, Takashi Kumada, Satoshi Nakano, Hideo Yamazaki, and Sachiko Tanaka

Subjects
Gastroenterology
Published
1985
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