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110 results on '"Palotie, Aarno"'

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1. Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance

2. Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases

3. Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

4. FinnGen provides genetic insights from a well-phenotyped isolated population

5. Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury

6. Genetic associations of protein-coding variants in human disease

7. Genome-wide association study of varicose veins identifies a protective missense variant in GJD3 enriched in the Finnish population

8. Genetic associations of protein-coding variants in human disease

9. Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

10. The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia

11. Rare coding variants in ten genes confer substantial risk for schizophrenia

12. Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder

13. A novel variant in SMG9 causes intellectual disability, confirming a role for nonsense-mediated decay components in neurocognitive development

14. Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer

15. Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences

16. Genome-wide association study identifies 48 common genetic variants associated with handedness

17. Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics

18. Genome-wide association study identifies 48 common genetic variants associated with handedness

19. A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

20. Narrow-sense heritability estimation of complex traits using identity-by-descent information

21. Combined effects of genotype and childhood adversity shape variability of DNA methylation across age

22. Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants

23. Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes

25. Genome-wide association study identifies 48 common genetic variants associated with handedness

26. A data-driven medication score predicts 10-year mortality among aging adults

27. GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

28. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

29. Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022

30. Correction: Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population

31. Leveraging European infrastructures to access 1 million human genomes by 2022

32. Assessment of genetic variant burden in epilepsy-associated brain lesions

33. Roadmap for a precision-medicine initiative in the Nordic region

34. Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population

35. Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

36. Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland

37. Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

38. Phenome-wide association studies across large population cohorts support drug target validation

39. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

40. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

41. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

42. CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

43. Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene

44. An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

45. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

46. Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

47. Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

48. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

49. Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

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