1. The coexistence of carotid and lower extremity atherosclerosis further increases cardio-cerebrovascular risk in type 2 diabetes
- Author
-
Yuqian Bao, Cui-Chun Zhao, Ting-Ting Li, Mei-Fang Li, Ming-Yun Chen, Weiping Jia, Yinfang Tu, Junxi Lu, Lianxi Li, and Rong Zhang
- Subjects
Carotid Artery Diseases ,Male ,Cross-sectional study ,Endocrinology, Diabetes and Metabolism ,Comorbidity ,Type 2 diabetes ,030204 cardiovascular system & hematology ,Carotid Intima-Media Thickness ,0302 clinical medicine ,Cardio-cerebrovascular events ,Risk Factors ,Carotid atherosclerosis ,Odds Ratio ,Prevalence ,Original Investigation ,Middle Aged ,Hospitalization ,Lower Extremity ,cardiovascular system ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,Risk assessment ,Adult ,China ,medicine.medical_specialty ,Heart Diseases ,Lower limb atherosclerosis ,030209 endocrinology & metabolism ,Risk Assessment ,Self-reported cardio-cerebrovascular diseases ,Peripheral Arterial Disease ,03 medical and health sciences ,Diabetes mellitus ,Internal medicine ,medicine ,Humans ,cardiovascular diseases ,Aged ,Angiology ,business.industry ,Ultrasonography, Doppler ,Odds ratio ,medicine.disease ,Surgery ,Cerebrovascular Disorders ,Cross-Sectional Studies ,Logistic Models ,Diabetes Mellitus, Type 2 ,Concomitant ,business - Abstract
Background Both carotid and lower limb atherosclerosis are associated with increased cardiovascular and cerebrovascular risks. However, it is still unclear whether the concomitant presence of carotid and lower extremity atherosclerosis further increases the cardiovascular and cerebrovascular risks. Therefore, our aim is to investigate whether the coexistence of carotid and lower extremity atherosclerosis was associated with higher cardiovascular and cerebrovascular risks in patients with type 2 diabetes. Methods This cross-sectional study was performed in 2830 hospitalized patients with type 2 diabetes. Based on carotid and lower limb Doppler ultrasound results, the patients were divided into three groups including 711 subjects without atherosclerosis, 999 subjects with either carotid or lower limb atherosclerosis, and 1120 subjects with both carotid and lower limb atherosclerosis. And we compared the clinical characteristics and prevalence of both cardio-cerebrovascular events (CCBVEs) and self-reported cardio- cerebrovascular diseases (CCBVDs) among the three groups. Results After adjusting for age, sex, and duration of diabetes, there were significant increases in the prevalence of both CCBVEs (3.8 vs. 11.8 vs. 26.4 %, p
- Published
- 2016
- Full Text
- View/download PDF