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The coexistence of carotid and lower extremity atherosclerosis further increases cardio-cerebrovascular risk in type 2 diabetes

The coexistence of carotid and lower extremity atherosclerosis further increases cardio-cerebrovascular risk in type 2 diabetes

Authors :
Yuqian Bao
Cui-Chun Zhao
Ting-Ting Li
Mei-Fang Li
Ming-Yun Chen
Weiping Jia
Yinfang Tu
Junxi Lu
Lianxi Li
Rong Zhang
Source :
Cardiovascular Diabetology
Publication Year :
2016
Publisher :
Springer Science and Business Media LLC, 2016.

Abstract

Background Both carotid and lower limb atherosclerosis are associated with increased cardiovascular and cerebrovascular risks. However, it is still unclear whether the concomitant presence of carotid and lower extremity atherosclerosis further increases the cardiovascular and cerebrovascular risks. Therefore, our aim is to investigate whether the coexistence of carotid and lower extremity atherosclerosis was associated with higher cardiovascular and cerebrovascular risks in patients with type 2 diabetes. Methods This cross-sectional study was performed in 2830 hospitalized patients with type 2 diabetes. Based on carotid and lower limb Doppler ultrasound results, the patients were divided into three groups including 711 subjects without atherosclerosis, 999 subjects with either carotid or lower limb atherosclerosis, and 1120 subjects with both carotid and lower limb atherosclerosis. And we compared the clinical characteristics and prevalence of both cardio-cerebrovascular events (CCBVEs) and self-reported cardio- cerebrovascular diseases (CCBVDs) among the three groups. Results After adjusting for age, sex, and duration of diabetes, there were significant increases in the prevalence of both CCBVEs (3.8 vs. 11.8 vs. 26.4 %, p

Details

ISSN :
14752840
Volume :
15
Database :
OpenAIRE
Journal :
Cardiovascular Diabetology
Accession number :
edsair.doi.dedup.....a24c1b69a88659b6e24fa5f544a663af
Full Text :
https://doi.org/10.1186/s12933-016-0360-2