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The coexistence of carotid and lower extremity atherosclerosis further increases cardio-cerebrovascular risk in type 2 diabetes
The coexistence of carotid and lower extremity atherosclerosis further increases cardio-cerebrovascular risk in type 2 diabetes
- Source :
- Cardiovascular Diabetology
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Background Both carotid and lower limb atherosclerosis are associated with increased cardiovascular and cerebrovascular risks. However, it is still unclear whether the concomitant presence of carotid and lower extremity atherosclerosis further increases the cardiovascular and cerebrovascular risks. Therefore, our aim is to investigate whether the coexistence of carotid and lower extremity atherosclerosis was associated with higher cardiovascular and cerebrovascular risks in patients with type 2 diabetes. Methods This cross-sectional study was performed in 2830 hospitalized patients with type 2 diabetes. Based on carotid and lower limb Doppler ultrasound results, the patients were divided into three groups including 711 subjects without atherosclerosis, 999 subjects with either carotid or lower limb atherosclerosis, and 1120 subjects with both carotid and lower limb atherosclerosis. And we compared the clinical characteristics and prevalence of both cardio-cerebrovascular events (CCBVEs) and self-reported cardio- cerebrovascular diseases (CCBVDs) among the three groups. Results After adjusting for age, sex, and duration of diabetes, there were significant increases in the prevalence of both CCBVEs (3.8 vs. 11.8 vs. 26.4 %, p
- Subjects :
- Carotid Artery Diseases
Male
Cross-sectional study
Endocrinology, Diabetes and Metabolism
Comorbidity
Type 2 diabetes
030204 cardiovascular system & hematology
Carotid Intima-Media Thickness
0302 clinical medicine
Cardio-cerebrovascular events
Risk Factors
Carotid atherosclerosis
Odds Ratio
Prevalence
Original Investigation
Middle Aged
Hospitalization
Lower Extremity
cardiovascular system
Cardiology
Female
Cardiology and Cardiovascular Medicine
Risk assessment
Adult
China
medicine.medical_specialty
Heart Diseases
Lower limb atherosclerosis
030209 endocrinology & metabolism
Risk Assessment
Self-reported cardio-cerebrovascular diseases
Peripheral Arterial Disease
03 medical and health sciences
Diabetes mellitus
Internal medicine
medicine
Humans
cardiovascular diseases
Aged
Angiology
business.industry
Ultrasonography, Doppler
Odds ratio
medicine.disease
Surgery
Cerebrovascular Disorders
Cross-Sectional Studies
Logistic Models
Diabetes Mellitus, Type 2
Concomitant
business
Subjects
Details
- ISSN :
- 14752840
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Cardiovascular Diabetology
- Accession number :
- edsair.doi.dedup.....a24c1b69a88659b6e24fa5f544a663af
- Full Text :
- https://doi.org/10.1186/s12933-016-0360-2