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Your search keyword '"Jassem, Wayel"' showing total 11 results
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11 results on '"Jassem, Wayel"'

2. A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures

Author

Warner, Ben, primary, Harrison, Phillip, additional, Farman, Muhammad, additional, Devlin, John, additional, Reffitt, David, additional, El-Sherif, Yasser, additional, Khorsandi, Shirin E., additional, Prachalias, Andreas, additional, Cerisuelo, Miriam Cortes, additional, Menon, Krish, additional, Jassem, Wayel, additional, Srinivasan, Parthi, additional, Vilca-Melendez, Hector, additional, Heneghan, Michael, additional, Heaton, Nigel, additional, and Joshi, Deepak, additional

Published
2020
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3. Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors

Author

Segal, Joe M., primary, Kent, Deniz, additional, Wesche, Daniel J., additional, Ng, Soon Seng, additional, Serra, Maria, additional, Oulès, Bénédicte, additional, Kar, Gozde, additional, Emerton, Guy, additional, Blackford, Samuel J. I., additional, Darmanis, Spyros, additional, Miquel, Rosa, additional, Luong, Tu Vinh, additional, Yamamoto, Ryo, additional, Bonham, Andrew, additional, Jassem, Wayel, additional, Heaton, Nigel, additional, Vigilante, Alessandra, additional, King, Aileen, additional, Sancho, Rocio, additional, Teichmann, Sarah, additional, Quake, Stephen R., additional, Nakauchi, Hiromitsu, additional, and Rashid, S. Tamir, additional

Published
2019
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4. Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Author

Zhao, Yuan, primary, Uduman, Mohamed, additional, Siu, Jacqueline H. Y., additional, Tull, Thomas J., additional, Sanderson, Jeremy D., additional, Wu, Yu-Chang Bryan, additional, Zhou, Julian Q., additional, Petrov, Nedyalko, additional, Ellis, Richard, additional, Todd, Katrina, additional, Chavele, Konstantia-Maria, additional, Guesdon, William, additional, Vossenkamper, Anna, additional, Jassem, Wayel, additional, D’Cruz, David P., additional, Fear, David J., additional, John, Susan, additional, Scheel-Toellner, Dagmar, additional, Hopkins, Claire, additional, Moreno, Estefania, additional, Woodman, Natalie L., additional, Ciccarelli, Francesca, additional, Heck, Susanne, additional, Kleinstein, Steven H., additional, Bemark, Mats, additional, and Spencer, Jo, additional

Published
2018
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5. A multicentre randomised controlled trial to compare the efficacy of ex-vivo normothermic machine perfusion with static cold storage in human liver transplantation

Author

Nasralla, David, primary, Nasralla, David, additional, Akhtar, Mohammed Zeeshan, additional, Bradley, Ally, additional, Butler, Andrew, additional, Chiocchia, Virginia, additional, Dutton, Susan, additional, García-Valdecasas, Juan Carlos, additional, Imber, Charles, additional, Jassem, Wayel, additional, Knight, Simon, additional, Mergental, Hynek, additional, Paul, Andreas, additional, Pirenne, Jacques, additional, Ploeg, Rutger, additional, Coussios, Constantin C, additional, and Friend, Peter J, additional

Published
2018
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8. Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction

Author

Xu, Jin, primary, Casas-Ferreira, Ana M., additional, Ma, Yun, additional, Sen, Arundhuti, additional, Kim, Min, additional, Proitsi, Petroula, additional, Shkodra, Maltina, additional, Tena, Maria, additional, Srinivasan, Parthi, additional, Heaton, Nigel, additional, Jassem, Wayel, additional, and Legido-Quigley, Cristina, additional

Published
2015
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9. The effect of body position on compartmental intra-abdominal pressure following liver transplantation

Author

Cresswell, Adrian B, primary, Jassem, Wayel, additional, Srinivasan, Parthi, additional, Prachalias, Andreas A, additional, Sizer, Elizabeth, additional, Burnal, William, additional, Auzinger, Georg, additional, Muiesan, Paolo, additional, Rela, Mohammed, additional, Heaton, Nigel D, additional, Bowles, Matthew J, additional, and Wendon, Julia A, additional

Published
2012
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11. A randomized trial of normothermic preservation in liver transplantation

Author

Nasralla, David, Coussios, Constantin C, Mergental, Hynek, Akhtar, M Zeeshan, Butler, Andrew J, Ceresa, Carlo DL, Chiocchia, Virginia, Dutton, Susan J, García-Valdecasas, Juan Carlos, Heaton, Nigel, Imber, Charles, Jassem, Wayel, Jochmans, Ina, Karani, John, Knight, Simon R, Kocabayoglu, Peri, Malagò, Massimo, Mirza, Darius, Morris, Peter J, Pallan, Arvind, Paul, Andreas, Pavel, Mihai, Perera, M Thamara PR, Pirenne, Jacques, Ravikumar, Reena, Russell, Leslie, Upponi, Sara, Watson, Chris JE, Weissenbacher, Annemarie, Ploeg, Rutger J, Friend, Peter J, and Consortium For Organ Preservation In Europe

Subjects
Adult, Aged, 80 and over, Male, Adolescent, Waiting Lists, Graft Survival, Temperature, Organ Preservation, Length of Stay, Middle Aged, Allografts, Survival Analysis, Tissue Donors, 3. Good health, Liver Transplantation, Perfusion, Young Adult, Treatment Outcome, Liver, Tissue and Organ Harvesting, Humans, Female, Bile Ducts, Aged
Abstract

Liver transplantation is a highly successful treatment, but is severely limited by the shortage in donor organs. However, many potential donor organs cannot be used; this is because sub-optimal livers do not tolerate conventional cold storage and there is no reliable way to assess organ viability preoperatively. Normothermic machine perfusion maintains the liver in a physiological state, avoids cooling and allows recovery and functional testing. Here we show that, in a randomized trial with 220 liver transplantations, compared to conventional static cold storage, normothermic preservation is associated with a 50% lower level of graft injury, measured by hepatocellular enzyme release, despite a 50% lower rate of organ discard and a 54% longer mean preservation time. There was no significant difference in bile duct complications, graft survival or survival of the patient. If translated to clinical practice, these results would have a major impact on liver transplant outcomes and waiting list mortality.

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