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The article focuses on Lawrence Steinman, a neurologist from Stanford University in Palo Alto, California who studied the role of protein αB-crystallin (CRYAB), an eye lens protein in the neurological disease multiple sclerosis. The work of Steinman distinguished CRYAB as a central agent in controlling inflammation and programmed cell death in the brain. Steinman's team has also shown that CRYAB likewise tones down many inflammatory pathways and helps in preventing programmed cell death.

In recent times, phenomena of conversational asymmetry have become a lively object of study for linguists, philosophers of language and moral philosophers—under various labels: illocutionary disablement and silencing (Langton in Philos Public Affairs 22:293–330, 1993; Hornsby and Langton in Legal Theory 4:21–37, 1998), discursive injustice (Kukla in Hypatia 29(2):440–457, 2014; Lance and Kukla in Ethics 123:456–478, 2013), illocutionary distortion (Green in The Stanford encyclopedia of philosophy, Stanford University Press, Palo Alto, 2014, Oxford handbooks online, Oxford University Press, Oxford, 2017). The common idea is that members of underprivileged groups sometimes have trouble performing particular speech acts that they are entitled to perform: in certain contexts, their performative potential is somehow undermined, and their capacity to do things with words is distorted or even annulled. In this paper I will assess this idea, focusing on Rebecca Kukla's and Rae Langton's accounts; in particular, I will criticize the role the notion of uptake plays in their accounts, and claim that it may ultimately undermine the very idea of discursive injustice. While, according to Kukla and Langton, members of disadvantaged groups are victims of a kind of uptake failure, leading to illocutionary disablement and even silencing, in the account I present they are victims of a kind of communicative (neither illocutionary nor perlocutionary) disablement. My overall aim is to develop a notion of discursive injustice that is more plausible and more effective for our broader purposes of criticising the structures of power and oppression. [ABSTRACT FROM AUTHOR]

When, in the winter of 1994, under the supervision of my postdoc adviser André Journel, I started writing Geostatistics for Natural Resources Evaluation in the bedroom of a tiny Palo Alto apartment, little did I know that 25 years later I would be conducting National Institutes of Health (NIH)-funded research on medical geostatistics from a lakefront office nestled in the Irish Hills of Michigan. The professional and personal path that led me to trade the mapping of heavy-metal concentrations in the topsoil of the Swiss Jura for the geostatistical analysis of cancer data was anything but planned, yet André's help and guidance were instrumental early on. Looking back, shifting scientific interest from the characterization of contaminated sites to human health made sense, as the field of epidemiology is increasingly concerned with the concept of exposome, which comprises all environmental exposures (e.g., air, soil, and drinking water) that a person experiences from conception throughout the life course. Although both environmental and epidemiological data exhibit space–time variability, the latter have specific characteristics that required the adaptation of traditional geostatistical tools, such as semivariogram and kriging. Challenges include: (i) the heteroscedasticity of disease rate data (i.e., larger uncertainty of disease rates computed from small populations), (ii) their uneven spatial support (e.g., rates recorded for administrative units of different size and shape), and (iii) the limitations of Euclidean metrics to embody proximity when dealing with data that pertain to human mobility. Most of these challenges were addressed by borrowing concepts developed in adjacent fields, stressing the value of interdisciplinary research and intellectual curiosity, something I learned as a fresh PhD in agronomical sciences joining André's research group at the Stanford Center for Reservoir Forecasting in the early 1990s. [ABSTRACT FROM AUTHOR]

Describes a case example of a treatment outcome and client satisfaction assessment program at the Children's Health Council, a private nonprofit agency affiliated with Stanford University in Palo Alto, California. Institution's provision of comprehensive mental health services for children and families; Utility of the described program for mental health professionals.

The article presents the study conducted by Stanford University researcher Carla Shatz and her colleagues regarding the immune connection of the brain in Palo Alto, California. The researchers have used mice aiming to determine the linked between the strengthening and breaking of the neurons during brain development. The study shows that the two family members of the proteins major histocompatibility complex class I (MHCI) limit the function of the circuitry which involved in the visual processing.