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Two new quinolin-2(1H)-ones, 7-methoxy-6-methyl-4-(4-methylfuran-2-yl)quinolin-2(1H)-one (1) and 7-hydroxy-6-methyl-4-(4-methylfuran-2-yl)quinolin-2(1H)-one (2), were isolated from the twigs of Cassia auriculata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 exhibited potential anti-TMV activity with inhibition rates of 38.4 and 49.2%, respectively. [ABSTRACT FROM AUTHOR]

Two new anti-tobacco mosaic virus (anti-TMV) xanthones, 4,7-dimethoxy-5-hydroxymethyl-1-methylxanthone (1) and 7-hydroxy-5-hydroxymethyl-4-methoxy-1-methylxanthone (2), were isolated from the whole plants of Comastoma pedunculatum. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 48.5 and 63.6%, respectively. These rates are higher than that of positive control. [ABSTRACT FROM AUTHOR]

Two new alkaloids, 3-(hydroxymethyl)-6,9-dimethyl-7H-benzo[de]quinolin-7-one ( 1) and 3-(hydroxymethyl)-8-methoxy-6,9-dimethyl-7H-benzo[de]quinolin-7-one ( 2), together with two known alkaloids ( 3 and 4) were isolated from the seeds of Cassia alata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1-4 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results revealed that compounds 1-4 have potential anti-TMV activity with inhibition rates of 29.2, 38.5, 24.2, and 28.8% at the concentration of 20 μM, respectively. The inhibition rates of 1 and 2 are higher than that of the postive control. [ABSTRACT FROM AUTHOR]

Two new anthraquinones, alataquinones A and B ( 1 and 2), together with two known anthraquinones ( 3 and 4), were isolated from the barks of Cassia alata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1-4 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1-4 exhibited moderate anti-TMV activity with inhibition rates in the range of 22.8-26.4%. [ABSTRACT FROM AUTHOR]

Two new isoquinoline alkaloids, fistulaquinolines A and B ( 1 and 2), were isolated from the barks of Cassia fistula. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that the two compounds showed weak anti-TMV activity with inhibition rates of 18.9 and 22.6%. [ABSTRACT FROM AUTHOR]