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Two New Alkaloids from the Seeds of Cassia alata and Their Anti-Tobacco Mosaic Virus Activity.
- Source :
- Chemistry of Natural Compounds; Nov2017, Vol. 53 Issue 6, p1127-1130, 4p
- Publication Year :
- 2017
-
Abstract
- Two new alkaloids, 3-(hydroxymethyl)-6,9-dimethyl-7H-benzo[de]quinolin-7-one ( 1) and 3-(hydroxymethyl)-8-methoxy-6,9-dimethyl-7H-benzo[de]quinolin-7-one ( 2), together with two known alkaloids ( 3 and 4) were isolated from the seeds of Cassia alata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1-4 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results revealed that compounds 1-4 have potential anti-TMV activity with inhibition rates of 29.2, 38.5, 24.2, and 28.8% at the concentration of 20 μM, respectively. The inhibition rates of 1 and 2 are higher than that of the postive control. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00093130
- Volume :
- 53
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Chemistry of Natural Compounds
- Publication Type :
- Academic Journal
- Accession number :
- 126486583
- Full Text :
- https://doi.org/10.1007/s10600-017-2215-9