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The second edition of this book offers six new chapters covering the latest developments in quantitative medical imaging, including artificial intelligence, MRI mapping, sonography, elastography and cardiac CT. All the other existing chapters have been updated and expanded, many with new text and figures, to reflect the rapid translation and advancement of technology in this exciting area of biomedical research. This updated edition presents fundamental knowledge on the imaging quantification of biophysical parameters for clinical diagnostic purposes. Clinical imaging scanners are considered by the authors as physical measurement systems capable of quantifying intrinsic parameters for the representation of the constitution and biophysical properties of tissues in vivo. In one respect, this approach fosters the development of new imaging methods for highly reproducible, system-independent, and quantitative biomarkers. These methods are greatly detailed in the book. Alternatively, this new edition equips the reader with a better understanding of how the physical properties of tissues interact with signal generation in medical imaging, opening up new insights into the complex and fascinating relationship between structure and function in living tissues. This updated edition is of interest to all those who recognize the limitations of clinical diagnosis based primarily on visual inspection of images, and who wish to learn more about the diagnostic potential of quantitative, biophysically-based medical imaging markers, as well as the challenges posed by the scarcity of such markers for next-generation imaging technologies.

This book comprises the select peer-reviewed proceedings of the 8th Asian Conference on Mechanics of Functional Materials and Structures (ACMFMS 2022). It aims to provide a comprehensive and broad-spectrum picture of the state-of-the-art research and development in diverse areas, such as contact mechanics, biomechanics and biomaterials, fracture and damage mechanics, impact mechanics and dynamic materials, structural health monitoring, and mechanics of functional and smart structures, among others. This book is a valuable resource for researchers and professionals working in academia and industry in the areas of mechanical engineering.

Das Standardwerk für alle in der Geburtshilfe und Perinatalmedizin tätigen Ärztinnen und Ärzte und Interessierte liegt nun unter neuer Herausgeberschaft vor. In der 6. Auflage komplett aktualisiert und dem aktuellen evidenzbasierten Wissen und Methoden angepasst. Mehr als die Hälfte der Kapitel mit neuer Autorenschaft und erweitert um neue Themen, u.a. Adipositas und Schwangerschaft, Geburtsmodus bei fetalen Fehlbildungen, Management von Placenta increta, Patient Blood Management. Plus: Von der Evidenz zur Handlungsempfehlung, praktisches geburtshilfliches multiprofessionelles Traning. „Die Geburtshilfe“ beantwortet die zahlreichen Fragen, die sich Ärztinnen und Ärzte und Hebammen rund um die Themen Schwangerschaft, Geburt und Perinatalmedizin stellen. Verständlich, klar strukturiert und an der Praxis orientiert mit eindeutigen Angaben zur Dosierung von Medikamenten, Algorithmen und Hinweisen auf Komplikationen. Als ebook und Live-Reference ermöglicht es den direkten Zugriff zu jeder Zeit sowie auf Links zu wichtigen Websites. Für eine kompetente und einfühlsame Betreuung und Begleitung der werdenden Mutter von der Schwangerschaft bis nach der Entbindung.

Soft tissue simulants, essential for automotive and ballistic testing, medical, and surgical training, have traditionally relied on cadavers and animal tissues. However, their biomechanical properties change with time due to dehydration after death and the biomechanics of the animal models cannot be translated and compared with the human tissues. This book compiles various synthetic tissues used in these applications, addressing their characterization and industry-wide applications. While older simulants lack biofidelity, recent advancements in biofidelic soft tissue simulants offer promising alternatives, yet technology transfer remains limited. This book fills the gap by exploring each simulant's characteristics and current trends, facilitating their adoption in clinical and academic settings. These synthetic tissues have the potential to replace live tissues in surgical training, streamlining biosafety approvals. They also benefit academic researchers by reducing costs and time in biomechanical testing. Anticipated to be the first of its kind, this comprehensive reference book will showcase recent advancements in soft tissue simulant development, serving as a cornerstone text in tissue engineering & biomedical engineering, medical simulation, biomechanics, and related fields.

This monograph brings forth biomechanical research methods and outcomes on human tissue experiments such as those of the brain and the heart under a single umbrella. Different mechanical characterization techniques employed in human tissue property estimation are presented in detail. The contents also focus on a hyperelastic constitutive model (e.g., Mooney-Rivlin, Ogden) for both isotropic and anisotropic tissue characterization. It also discusses energy dissipation in soft tissues and associated viscoelasticity. Human tissues, including skin, muscles, connective tissues, and tissues in all functional organs are listed and their mechanical properties are presented in detail. These tissue properties are indispensable for computational modeling of biological systems, validation of biomechanical tissue testing, medical simulation through development of artificial phantoms and surrogates, and testing of medical devices and interventions. This book will serve as a key reference forresearch in tissue engineering & biomedical engineering, medical simulation, biomechanics, finite element modeling of biological systems, biomaterials, biotechnology, implant and medical device development, and healthcare wearables.

This book chronicles the role of advanced nanomaterials and surface engineering technologies in the development of point-of-care biosensors for health and environmental monitoring. All aspects of nanomaterial synthesis and characterization, functionalization methods, sensing surface engineering, signal amplification strategies, use of innovative technologies to enhance sensor efficiency and performances, and innovative applications of nanobiosensors to tackle real-life problems are discussed in this book with a focus on optical and electrochemical based sensing. It also covers the detection of infectious diseases and various disease biomarkers, smartphone-based biosensing, and portable diagnostics module developments with a discussion on the working mechanisms of these devices in various domains. The book also illustrates the recent trends in biosensing, and an overview of the challenges and probable solutions for the translation of biosensors from laboratory prototypes to commercial success. ​

This book is the result of a collaboration between a human editor and an artificial intelligence algorithm to create a machine-generated literature overview of research articles analyzing the mediating role of social media on the psychological wellbeing of youth. It's a new publication format in which state-of-the-art computer algorithms are applied to select the most relevant articles published in Springer Nature journals and create machine-generated literature reviews by arranging the selected articles in a topical order and creating short summaries of these articles. In this volume, a human counsellor psychologist used the algorithm to explore articles that present results of research about the impacts of social media on the psychological wellbeing of youth. The Internet has always been popular among youth, but during the pandemic it has attracted even more attention since many aspects of life further migrated to the digital world, thus adding substantially to Internet'sever-increasing popularity. Today, youth spend a majority portion of their time on the Internet and an increasing amount on social media. In such digitally dependent times, this book attempts to provide insights on the positive and negative impact of the Internet and social media on youth mental health, and also provides specific observations on personality traits.

This book will provide readers with a good overview of some of most recent advances in the field of Photon Counting CT technology for X-ray medical imaging, especially as it pertains to new detectors. There will be a good mixture of general chapters in both technology and applications in CT medical imaging. The book will have an in-depth review of the research topics from world-leading specialists in the field. The conversion of the X-ray signal into analogue/digital value will be covered in some chapters. The authors also provide a review of CMOS chips for X-ray image sensors, methods of material discrimination and image reconstruction techniques.Covers a broad range of topics, including an introduction to novel spectral Computed Tomography;Includes in-depth analysis on how to optimize X-ray detection;Discusses analysis of electronics for X-ray detection.

This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.

The book Labour and delivery:Update discusses protocols for labour management from A to Z in a concise manner and easy to understand language. It covers latest guidelines for breech delivery, management of preterm labour and premature preterm rupture of membranes and labour complications.It revisits instrumental vaginal delivery as many gynecologists and obstetricians lack the skill for forceps and ventouse delivery.This book covers all the latest cochrane reviews,RCOG, NICE,ACOG guidelines and other studies for managing various labour conditions. It includes all the latest developments and research to keep the readers abreast with the latest evidence-based strategies.The book is a ready revision tool for busy practitioners, postgraduates, undergraduates,midwifes, and for those who want to focus on delivery and labour events.

This book offers readers an overview of some of the most recent advances in the field of technology for X-ray medical imaging. Coverage includes both technology and applications in SPECT, PET and CT, with an in-depth review of the research topics from leading specialists in the field. Coverage includes conversion of the X-ray signal into analogue/digital value, as well as a review of CMOS chips for X-ray image sensors. Emphasis is on high-Z materials like CdTe, CZT and GaAs, since they offer the best implementation possibilities for direct conversion X-ray detectors. The discussion includes material challenges, detector operation physics and technology and readout integrated circuits required to detect signals processes by high-Z sensors. Authors contrast these emerging technologies with more established ones based on scintillator materials. This book is an excellent reference for people already working in the field as well as for people wishing to enter it.

This book was the end product of life experiences, thoughts and intellectual wanderings of the author, who through his career and for the last twenty years was always serving all the three aspects of a Psychiatrist: He is a clinician, a researcher and an academic teacher. The book includes a comprehensive history of Psychiatry since antiquity and until today, with an emphasis not only on main events but also specifically and with much detail and explanations, on the chain of events that led to a particular development. At the center of this work is the question ‘What is mental illness?'and ‘Does free will exist?'. These are questions which tantalize Psychiatrists, neuroscientists, psychologists, philosophers, patients and their families and the sensitive and educated lay persons alike. Thus, the book includes a comprehensive review and systematic elaboration on the definition and the concept of mental illness, a detailed discussion on the issue of free will as well as the state ofthe art of contemporary Psychiatry and the socio-political currents it has provoked.Finally the book includes a description of the academic, social and professional status of Psychiatry and Psychiatrists and a view of future needs and possible developments. A last moment addition was the chapter on conspiracy theories, as a consequence of the experience with the social media and the public response to the COVID-19 outbreak which coincided with the final stage of the preparation of the book. Their study is an excellent opportunity to dig deep into the relation among human psychology, mental health, the society and politics and to swim in intellectually dangerous waters.

This edited book presents the latest information on epidemiology, pathophysiology, diagnosis, and some current topics covering all aspects of cerebral palsy. It offers a novel interpretation of a group of lifelong movement disorders, which now is an accepted notion that the causes of cerebral palsy are multifactorial rather than birth asphyxia. The book is organized into three parts, and it begins with illustrating the perspective of the disease. Then focuses on the relationship between clinical features of perinatal complications/events and cerebral palsy. The last part offers a hot topic of the prevention such as hypothermia, neuroprotection, and stem cell transfer. Since there is no cure for this congenital motor disability of cerebral origin, effective strategies for primary prevention are highly desirable. Effective strategies require an understanding of causal pathways and the Editor wishes to disseminate the experience and knowledge through this comprehensive volume to the readers.Cerebral Palsy - Perspective and Clinical Relation to Perinatal Complications/Events is a valuable source for clinicians, researchers, and medical staff who deal with the management of pregnancy and delivery. It also attracts clinicians worldwide who are interested in recent updates on this field.

This state-of-the-art book brings together the full range of issues that can inform care for patients experiencing the effects of concussion. Written by an international panel of experts and edited by a critical care physician and by a cognitive neuroscientist, the book serves as a primer of the various domains of study and application, while providing clinical insights and evidence to bring towards treatment. Chapters span the basic mechanics and pathophysiology of concussion, through its assessment, management, and complications. Comprehensive and timely, this book is accessible to healthcare professionals, and researchers eager to learn something about this field.

This textbook introduces the core competencies, tools and perspectives to manage free-ranging animal population health and demonstrates their need and relevance to help wildlife cope with the ever-increasing pressures of the Anthropocene, manifested by global megatrends such as climate change, urbanization and pollution. It adapts and adopts key concepts of population health from public health and herd health to a wildlife health context. In a highly-accessible and unique form, this book presents a modern way of approaching wildlife and fish epidemiology, health promotion and disease control, with a focus on the social dimensions of wildlife health management. Aimed at graduate students in veterinary medicine, wildlife researchers and health managers this textbook provides a valuable source of information to foster the knowledge and skills needed to protect and promote the health of free-ranging wildlife.

This book is an advanced textbook and a reference book for the post-graduate plant-breeding students and the plant breeders. It consolidates fundamental concepts and also the latest advances in plant-breeding practices including development in crop genomics. It contains crop wise explanation on origin, reproduction, genetics of yield contributing traits, biotic and abiotic stresses, nutritional improvement and crop specific plant-breeding procedures and techniques. The chapters are planned to describe crop-focused breeding procedure for the major crop plants as per their economic importance. The recent developments in breeding of field crops have been reported. The recent progress made in mapping traits of economic importance has been critically reviewed for each crop. The progress made in markers assisted selected in few crops has been summarized. This book bridges the knowledge gap and bring to the researchers and students information on modern breeding tools for developing biotic and abiotic stress tolerant, climate resilient and micronutrient rich varieties of field crops. The chapters in book are contributed by experienced Plant Breeders.

This book had its beginning in 1967 when Shirley G. Driscoll and Kurt Benirschke wrote in English the volume on placental pathology for the Henke-Lubarsch, the noted German Handbook of Pathology. There seemed to be a need for wider distribution of the text and it was reprinted by Springer Verlag, New York, essentially the only book available devoted just to the human placenta. Dr. Benirschke authored 5 subsequent editions in collaboration with Peter Kaufmann, Rebecca Baergen and Graham Burton in 1990 (2nd edition), 1995 (3rd edition), 2000 (4th edition), 2006 (5th edition) and 2012 (6th edition). In the early editions, the most important material was in a larger font than the extensive review of exceptions and the discussion in the literature. Since 1967, many other shorter placenta books have been published in English, French and German. None of these have included the breadth of discussion or the voluminous references which includes details of many historicarticles, not readily available. Interest in the placenta has wildly expanded over the intervening 50+ years with the vast majority of Pathologists, Obstetricians and Pediatricians recognizing its value. In addition, there are now quite a few new journals, societies and meetings devoted to the placenta in both clinical and research areas. The interest extends into areas of study well beyond the realm of anatomic pathology.The 7th edition will, of necessity, differ from the prior editions which Dr. Benirschke wrote largely himself at first, and later with the help of the above noted co-authors. It will now be an international multi-authored book with nearly 40 contributors revising one or more chapters. The explosion of new information as necessitating some reordering of chapters and adding completely new chapters including Chapters 31 and 32, “Innovations in Placental Pathology” and “Imaging in Placental Pathology”. Dr. Burton's section has been extensively edited, as well. The editors gave the new authors considerable latitude in how to write the new and/or edited chapters. Many of the revised chapters retain much of Dr. Benirschke's anecdotal information as well as the voluminous references. Others are more modern in their approach. All contain substantial new references and current information. It is our hope that Benirschke's Pathology of the Human Placenta will remain as a mainstay reference in placental pathology.It aims to help readers gain a broad understanding of how placental architecture is shaped during normal development, with a view to appreciating how this may be perturbed in complications of pregnancy.

This handbook covers the fundamental principles of interactions of particles with matter and of most types of detectors used in many fields of physics, starting from particle physics, nuclear physics up to recent experiments for solid state physics. In this second edition chapters are updated to include the most recent developments in detector physics and additional chapters on new types of detectors, like silicon photomultipliers, have been added. In addition the section about medical applications has been extended. All major detector types are described in detail by leading experts in these fields. It also gives deep insight into many applications from homeland security over radiation protection to a whole section about medical physics with strong emphasis on nuclear medicine. The book is suited to achieve a deep knowledge in the field of detector physics and imaging. It can also be used as a reference book to look up the working principles of a given detector type and to get an overview of state-of-the-art applications of the various detector types. It is also helpful for practitioners in nuclear medicine and radiology as it summarizes all detector types in this field and the basic working principles of these detectors. The area of radiation therapy is also covered in detail taking into account the most recent developments.

Dieses Nachschlagewerk richtet sich an Studierende von gesundheitsbezogenen Studiengängen sowie Wissenschaftler im Gesundheitsbereich und bietet fachgebietsübergreifend und interdisziplinär das gesamte Wissen im Bereich Prävention und Gesundheitsförderung stets top aktuell und gebündelt in hervorragender Qualität. Die einzelnen Sektionen behandeln sowohl die Bedeutungen und Grundlagen, Konzepte und Methoden, als auch die wichtigsten Akteure im deutschen Gesundheitswesen. Berücksichtigt werden dabei die sozialen und umweltbezogenen Determinanten, die verschiedenen Risikofaktoren und Risikoverhalten, sowie die rechtlichen Grundlagen und die gesundheitspolitische Umsetzung. Das Standardwerk richtet sich an Studierende, Wissenschaftlerinnen und Wissenschaftler unterschiedlicher Disziplinen im Gesundheitsbereich sowie an Expertinnen und Experten aus der Praxis.

This book presents a series of empirically based case studies conducted by social change scholars from Asia-Pacific, showcasing the latest social marketing approaches geared at improving societal well-being in the region. Cutting across cultural perspectives, the contents gather ideas on social marketing campaigns and strategies from around the region and use these case studies as a platform to address concomitant challenges in employing marketing tools to positively change social behaviour. The selection of case studies covers and compares aspects of public health and well-being, and public environmental consciousness in terms of driving attitudes towards implementing improved sustainability in developing and developed countries. Drawing on related policies and legislation, and examining social behaviour at the individual, community, and organisational levels, the authors propose innovative new methods in social marketing and social change research. The book is of interest to researchers and practitioners in social marketing, business ethics, behavioural science, public health, and development studies.

Now in a fully revised and expanded second edition, this comprehensive text remains a timely and major contribution to the literature that addresses the neuromechanisms, predispositions, and latest developments in the evaluation and management of concussive injuries. Concussion, also known as mild traumatic brain injury, continues to be a significant public health concern with increased attention focusing on treatment and management of this puzzling epidemic as well as controversies within the field. The book is comprised of five thematic sections: current developments in evaluation; biomechanical mechanisms; neural substrates, biomarkers, genetics and brain imaging; pediatric considerations; and clinical management and rehabilitation. Since the publication of the original edition in 2014, much has changed regarding the current understanding of mild traumatic brain injury including development of more precise imaging modalities, development and classification of new biomarkers, and updates to clinical treatment and management of athletic concussion. This new edition will include new chapters targeting the influence of genetics on concussive injury, as well as an expansion on the knowledge of pediatric response to concussion and the influence of repetitive subconcussive impacts on athlete health. An invaluable contribution to the literature, Concussions in Athletics: From Brain to Behavior reestablishes itself as a state-of-the-art reference that will be of significant interest to a wide range of clinicians, researchers, administrators, and policy makers, and this updated version aims to narrow the gap between research findings and clinical management of sports-related concussion and other mild traumatic brain injury. The second edition also attempts to broaden the scope of the knowledge to apply to more professionals and pre-professionals in the fields of neuroscience, neuropsychology, and other allied health professionals that closely work with athletes and sports medicine professionals.

This volume explores the main applications of elastographic techniques in hepatological and gastroenterological diseases, and elaborates on the use of these diagnostic techniques in a broad range of clinical settings; in this regard, it provides a clear critical methodological approach to the correct indication, taking into account the existing diagnostic pathways, the actual diagnostic accuracy of elastographic techniques, and their impact on clinical practice in terms of correct positioning of the test in the diagnostic pathway and clinical outcomes improvement. In the first chapters, which focus on the correct methodology for Diagnostic Accuracy Assessment of non -invasive techniques, the architecture of diagnostic research is discussed. In turn, the following sections describe a broad range of clinical applications in hepatology and gastroenterology. The closing section presents a number of case studies on practical issues, together with acritical discussion on how to promote the appropriate use of these technologies. Given its scope, the book will be of interest to specialists, post-graduate medical students, and researchers in the fields of hepatology and gastroenterology.

This book provides a comprehensive overview of the diagnosis and management of diseases of the biliary tree. Topics covered include: congenital biliary abnormalities, genetic cholangiopathies, autoimmune cholangiopathies, inflammatory and drug-related cholangiopathies, and cholangiocarcinoma. Given their particular importance (even for clinicians working with adults), pediatric conditions are also examined. In addition, a special section is devoted to pregnancy and diseases of the biliary tree, and to transplants and diseases of the biliary tree. Each chapter offers up-to-date information on the management of the diseases discussed. Moreover, the book addresses new treatments for autoimmune cholestatic liver diseases, reflecting the new therapeutic targets that have recently been discovered. Examples include farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR)-agonists, together with new drugs that affect the composition of bile flow. Given its scope, the book offers a valuable guide for a broad range of practitioners.

This book explains, in a straightforward way, the foundations upon which electoral techniques are based in order to shed new light on what we actually do when we vote. The intention is to highlight the fact that no matter how an electoral system has been designed, and regardless of the intentions of those who devised the system, there will be goals that are impossible to achieve but also opportunities for improving the situation in an informed way. While detailed descriptions of electoral systems are not provided, many references are made to current or past situations, both as examples and to underline particular problems and shortcomings. In addition, a new voting method that avoids the many paradoxes of voting theory is described in detail. While some knowledge of mathematics is required in order to gain the most from the book, every effort has been made to ensure that the subject matter is easily accessible for non-mathematicians, too. In short, this is a book for anyone who wants to understand the meaning of voting.

Empathisch und zugleich selbst gesund bleiben, das ist das Ziel des empCARE-Trainings. Unter der Leitung des Institutes für Psychologie an der Universität Duisburg Essen wurden in einem dreijährigen vom BMBF geförderten Projekt exemplarisch Pflegende am Universitätsklinikum Köln, am Universitätsklinikum Bonn und beim Intensivpflegedienst Aaron aus Köln darin trainiert, Empathie strukturiert gegenüber anderen und gegenüber sich selbst reflektierter einzusetzen, um psychischen Belastungen präventiv vorzubeugen. Die präventive Wirkung auf die Gesundheit der Teilnehmerinnen und Teilnehmer konnte in der begleitenden Studie nachgewiesen werden. Noch ein Jahr nach dem Seminar zeigt sich ein messbar verbesserter Umgang mit Empathie. Damit verbunden ist eine Abnahme von Belastungssymptomen wie zum Beispiel Burnout und Depressivität.Neu ist, dass empCARE die Emotionen und Bedürfnisse der Beschäftigten der Gesundheits- und Sozialberufe selbst in den Blick nimmt. Sie lernen mit den Anforderungen in der Interaktionsarbeit besser zurecht zu kommen und gleichzeitig die eigene Gesundheit und Berufsmotivation zu stärken. Im Unterschied zu anderen Empathietrainingsprogrammen geht es nicht um die simple Verstärkung von Empathie gegenüber einer anderen Person, sondern um einen reflektierten Umgang mit der eigenen Empathie und die Stärkung der Selbstfürsorge. Das Training ist ein Beitrag zur Gesundheitsprävention der teilnehmenden Personen und reduziert Belastungsfaktoren, die aus der Interaktion mit Klientinnen und Klienten resultieren.

This book explores the pivotal role played by technology over the past decade in advancing global public health and health care. At present, the global community faces unprecedented healthcare challenges fueled by an aging population, rising rates of chronic disease, and persistent health disparities. New technologies and advancements have the potential to extend the reach of health professionals while improving quality and efficiency of service delivery and reducing costs within the public and the private health systems. The chapters highlight the barriers faced by the global healthcare workforce in using technology to promote health and human rights of communities:Role of Digital Health, mHealth, and Low-Cost Technologies in Advancing Universal Health Coverage in Emerging EconomiesTelehealth and Homecare AgenciesTechnology and the Practice of Health Education in Conflict ZonesThe Worldwide Digital Divide and Access to Healthcare TechnologyTechnology for Creating Better Professional Teams to Strengthen Healthcare SystemsGlobal Public Health Disaster Management and TechnologyAs a resource on the evolution of technology as a valuable and integral component in the promotion and practice of public health and health care, with a focus on SDG 3 targets, Technology and Global Public Health should engage students, instructors, practitioners, and other professionals interested in public health, universal health care, health technology, digital health, and health equity.Dr. Murthy has been a respected leader and mentor on scientific health-related matters within the UN system for many years. Her book develops a theoretical system connecting concepts that have coined global public health with the rapid development of technology, all with the focus to achieve Sustainable Development Goal number three, within the time frame set by World Leaders. - Henry L. Mac-Donald, Former Permanent Representative of Suriname to the United Nations

This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications. It highlights the complexity of nanoheterostructures, especially magnetic metal oxides, ferrites and doped magnetic nanomaterials, and discusses their potential applications in the early detection, imaging and treatment of cancer. It also covers the toxicity and risk assessment of multifunctional nanomaterials. Providing an overview of magnetic nanoheterostructures, it appeals to a wide audience, from beginners and graduate-level students to experts in academia and industry.

This book offers a comprehensive and topical depiction of advances in CT imaging. CT has become a leading medical imaging modality, thanks to its superb spatial and temporal resolution to depict anatomical details. New advances have further extended the technology to provide physiological information, enabling a wide and expanding range of clinical applications. The text covers the latest advancements in CT technology and clinical applications for a variety of CT types and imaging methods. The content is presented in seven parts to offer a structure across a board coverage of CT: CT Systems, CT Performance, CT Practice, Spectral CT, Quantitative CT, Functional CT, and Special Purpose CT. Each contain chapters written by leading experts in the field, covering CT hardware and software innovations, CT operation, CT performance characterization, functional and quantitative applications, and CT systems devised for specific anatomical applications. This book is an ideal resource for practitioners of CT applications in medicine, including physicians, trainees, engineers, and scientists.

From the unique perspective of a board certified obstetrician/gynecologist turned board certified dermatologist comes a much needed text focusing solely on the cutaneous disorders that occur during pregnancy. Written with the insider knowledge that education on pregnancy dermatoses is often underrepresented in OB/GYN and family medicine programs, this text will aid these practitioners in correctly assessing these issues and discussing next steps with their patients so that the topic of skin disease is no longer a struggle. Although dermatologic disease in pregnancy is part of the curriculum in dermatology residencies, dermatologists and other physicians also may not feel as comfortable prescribing topical or systemic treatments in their pregnant patients. This book will not only provide in-depth information about physiologic skin changes in pregnancy, pregnancy dermatoses, and pre-existing skin disease in pregnant patients, but treatment options and medication safety for various conditions will be covered in detail. Cutaneous Skin Disorders of Pregnancy is developed by dermatologists and OB/GYNs and will serve as an invaluable resource for General Dermatologists, Obstetricians/Gynecologists, Family Medicine doctors and midwives who deliver and/or care for pregnant women.

This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

Recently, magnetic nanostructures have gained a remarkable interest for basic research and applied studies. Because of their low cost and ease of manufacture and modification, they have great potential for agricultural and environmental applications. The use of magnetic nanostructures has been proven in a wide range of fields including catalysis, biotechnology, biomedicine, magnetic resonance imaging, agriculture, biosensors, and removal of environmental pollutants, among others. This book includes 16 chapters of collected knowledge, discoveries, and applications in agriculture, soil remediation, and water treatment. It describes the role of nano-agriculture with regard to food security and discusses environmental and agricultural protection concerns. It further offers potential applications of magnetic nanomaterials in the agriculture and food sectors, such as the development of sensors, environment monitoring for wastewater treatment and the remediationof contaminated soils. Increasing crop yield through the use of nanopesticides or nanofertilizers and biosecurity using sensors for detecting pathogens along the entire food chain are discussed as well. This book also brings together various sources of expertise on different aspects magnetic nanostructure application in the agri-food sector and environment remediation. Magnetic nanostructures also have great potential in biotechnological processes, as they can be utilized as a carrier for enzymes during different biocatalytic transformations. Novel magnetic nanomaterials can be used for detection and separation of pesticides from environmental and biological samples. The excellent adsorption capacity of the modified magnetic nanoadsorbents together with other advantages such as reusability, easy separation, environmentally friendly composition, and freedom of interferences of alkaline earth metal ions make them suitable adsorbents for removal of heavy metal ions from environmental and industrial wastes. One of the most important environmental applications of magnetic nanostructures has been in the treatment of water, whether in the remediation of groundwater or through the magnetic separation and/or sensing of contaminants present in various aqueous systems. The integrated combination of these 16 chapters, written by experts with considerable experience in their area of research, provides a comprehensive overview on the synthesis, characterization, application, environmental processing, and agriculture of engineered magnetic nanostructures. Its comprehensive coverage discusses how nanostructure materials interact in plants as well as their potential and useful applications.

This book provides an overview of the current applications of nanomaterials in brain diseases, and introduces several novel nanomaterials that have excellent potential in this field. During the last two decades, nanotechnology had matured significantly as it has transitioned from a bench-top science to an applied technology. However, the application of nanomaterials in basic and clinical neuroscience is still at an early stage, and understanding how the intrinsic properties of nanomaterials translate to complex biological responses is an area of intensive research. Part 1 of the book focuses on the principles and strategies of nanomedicine in the brain diseases, while part 2 examines the applications of promising nanomaterials for therapy and diagnosis in the brain. Together they offer a comprehensive picture of advances in nanotechnology and their successful use in treating brain diseases in the past 20 years.

This book presents essential information on modern location science – in a word, all you need to know about location. The second edition of this handbook has been fully revised throughout, with numerous updates and chapters added, to offer an even more comprehensive overview of methods and applications. The book is divided into three parts: basic concepts, advanced concepts and applications. Written by the most respected specialists in the field and thoroughly reviewed by the editors, it first lays out the fundamental problems in location science and provides readers with basic background information on location theory. Part II covers advanced models and concepts, broadening and expanding on the content presented in Part I. It also discusses important tools to help readers grasp and solve real-world location problems. Part III focuses on the links between location science and other areas like GIS, telecommunications, healthcare, rapid transit networks, districting problems and disaster events, and presents a wide range of applications to allow readers to understand the role of facility location in such areas and learn how to handle real-world location problems. The book is intended for researchers working on theory and applications involving location problems and models. It is also suitable as a textbook for graduate courses on facility location.