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This book collates updated knowledge about algal species which are present in the terrestrial environment particularly in soil. Contributions in this volume covers different topics such as morphology, ecology and applications of soil algae. Ecological significance of soil algae and their biotechnological importance are the key features of this book. Algae are ubiquitous and occur in almost all terrestrial environments and in soil, they majorly belong to the member of Chlorophycophyta, Cyanochloronta, Rhodophycophyta Euglenophycophyta, and Chrysophycophyta. The role of soil algae as fertilizer and for reclaiming the saline soil is well studied. Algae in soil benefits agricultural production, increase water retention capacity, reduced soil erosion, reduction of nutrient runoff, and provides nutrients. The added algae increase soil biodiversity, organic biomass, and the total humus content of the soil, beneficial for healthy soil. These soil algae diversities also have many biotechnological and industrial importance. This book is of interest and use to researchers of phycology, molecular biology, agriculture and biotechnology and also to scientists working on soil biology, agronomy and crop research. Also, the book serves as reading material for undergraduate and graduate students of microbiology, agriculture, molecular biology, and biotechnology. Researchers from biotechnological and biofertilizers companies will also find this to be a useful read.

This book creates a theoretical framework to consider the integration of computational thinking (CT) into learning and teaching processes in different contexts from a design-based learning (DBL) perspective, and presents various intervention studies. The chapters each focus on a different aspect of CT integration through DBL, providing an overview and discussing the benefits of integrating CT into the curriculum. The book also discusses the design thinking process and how it can be used to promote CT, focusing on CT concepts and considering perspectives on how these concepts can be integrated into DBL activities. It also explores how artificial intelligence (AI)-based design-oriented learning activities can be used to develop students'CT skills, examines the information technology (IT) concept of pattern recognition, and provides examples of how this can be integrated into DBL activities. It presents practical examples on integrating CT into the teaching-learning process from a design-based learning perspective, summarizes approaches to assessing CT skills, and discusses them in the context of design-based learning. Lastly, this book also conducts a bibliometric analysis of publication and citation trends in computational thinking research conducted in design-based learning.

Wollen Sie als Fachärztin oder Facharzt die Zusatzweiterbildung Intensivmedizin absolvieren oder in der Intensivmedizin arbeiten? Dann können Sie Ihr Wissen mit diesem Lernbuch oder der App SN Flashcards optimal überprüfen! Über 170 Multiple-Choice-Fragen mit kommentierten Antworten bringen Sie auf den aktuellen Stand von Themen der Intensivmedizin wie Pharmakotherapie, Atmung und Beatmung, Infektiologie, Notfälle und Komplikationen. Plus: Fallorientierte Fragen und Auszüge von über 70 wichtiger klinischer Studien mit Kernaussagen und neu: Aktualisierung bekannter Themen und Ergänzung um „Hot Topics“ der Intensivmedizin aufgrund aktueller Entwicklungen in der Literatur. Ideal für Fachärztinnen und Fachärzte der Anästhesiologie, Chirurgie, Innere Medizin, Neurochirurgie, Neurologie und Wiedereinsteiger•innen in der Intensivmedizin.

Technische Unterstützung für kompetente Fürsorge und Pflege!Dieses Buch zeigt den aktuellen Stand digitaler Innovation in der Pflege und richtet sich an diejenigen, die sich mit ihr auseinandersetzten und die Entwicklung vorantreiben. Prozessmanagement und Prozessoptimierung werden durch digitale Systeme vereinfacht, zusätzlich können technische Lösungen Pflegefachpersonen entlasten. Das ist wichtig, um Ressourcen zu erhalten und Personal richtig einzusetzen. Ziel ist es, die Attraktivität des Pflegeberufs zu erhöhen und gleichzeitig eine hohe Qualität der Pflege sicherzustellen.Welche Angebote und Erfahrungen wurden bisher gemacht und wie werden Produkte erfolgreich eingeführt? Warum sind valide Daten Grundlage einer guten Pflege? Welche ethischen Anforderungen sind zu erfüllen? Zu diesen relevanten und sensiblen Themen bieten die Autoren wissenschaftliche fundiertes und praxisnahes Wissen.

This book explores current research trends in the context of the explainable artificial intelligence's impact on the digital sustainability trend while delving into case studies on education, tourism, marketing, and finance. These trends are examined through various case studies utilizing distinct analytical methods. The chapters are expected to support scholars and postgraduate students in furthering their research in this field and in recognizing prospective advancements in the applications of artificial intelligence.

This book describes the development of animal models widely used in biomedical research using step-wise instructions and photographs. Showcasing a wide range of species from zebra fishes, birds, rodents, rabbits, dogs, and pigs, the book includes detailed methodology on how to work with these species and to develop various models. The animal models in neurology including stroke, Alzheimer's disease, Parkinson's disease, and Schizophrenia; Animal models in cancer research, sleep disorders, and cardiovascular diseases are described to meet the understanding of researchers who plan to replicate these models in their laboratories. In depth detailing on the development of targeted gene knockouts and transgenics, implantation models that are used in toxicology studies, and pharmacokinetic studies in pigs and dogs are a highlight. Further, the book describes pharmacologic, chemically induced, surgically induced, microbiologically induced, infectious models, models for neurobehavioral studies, oncology research, and pain research. The book has dedicated sections on anesthesia and analgesia and teaches procedures like venous cut-downs and cannulations in pigs and dogs, and endotracheal intubation, mechanical ventilation and thoracotomy in rodents and will serve as a self-training tool. Concepts in the field of animal model development are explained using examples. Sample size selection, study design, and statistical evaluation of experiments involving laboratory animals are explained to enable young researchers to practically understand the nuances. This book will be a valuable tool for academicians, students, scientists, and veterinarians and will benefit equally who are new to the field and who are already working with laboratory animals.

This edited volume presents the latest research focussing on current challenges on the deployment of smart technologies and pedagogies for supporting teaching and learning in the post-covid19 era. This is at the core of studying the evolution of the learning process, the role of technology-supported pedagogical approaches, and the progress of educational technology innovations in the context of digital transformation in education and professional training. A selection of the best papers from the Cognition and Exploratory Learning in the Digital Age (CELDA) Conference, 2022 are included in this volume, bringing together high-quality research on Smart Pedagogies in the Post-Pandemic Era; Smart Learning Technologies in the Post-Pandemic Era; and Case Studies of Smart Learning Environments. The volume contributes to the discussion of current issues in digital education between researchers, practitioners, and policymakers.

The nonlinear optical spectrum signal technology is a new type of optical characterization technology owing to its non-invasiveness and good biocompatibility. This book highlights a comprehensive introduction to the Stimulated Raman scattering (SRS), Anti-Stokes Raman Spectroscopy (CARS), Two-photon Excited Fluorescence (TPEF) and Second Harmonic Generation signals (SHG) technologies. The four types of nonlinear optical signals technologies, especially two-dimensional and three-dimensional imaging, have great application potential in physics, materials science, chemistry and biomedicine. The book covers principles, theoretical calculation methods, signal measurement methods and imaging specific methods. The theoretical part starts from the basics of nonlinear optics and the relationship with strong light, and gradually transitions to theoretical calculation methods for specific optical signals. it combines the classical theory and the quantum theory to help readers develop a thorough understanding of the technologies. The book is a good reference for graduate students majored in physics and chemistry and for researchers working on optics, photonics and materials science.

This book contains the second volume of proceedings of the ECAI 2024 Workshop on Intelligent Management Information Systems (IMIS 2024). IMIS 2024 was part of the 27th European Conference on Artificial Intelligence ECAI 2024, held in Santiago de Compostela from October 19, 2024, to October 24, 2024. The book discusses emerging challenges related to implementing artificial intelligence in management information systems. The main focus is put on knowledge management and machine learning methods in information systems, artificial intelligence for decision support systems, intelligent customer management methods, hybrid artificial intelligence, and multiple criteria decision analysis methods and advanced computational methods for support business processes and decision-making. The book is divided into three major parts covering the main issues related to the topic. The first part presents issues related to the knowledge management in intelligent information systems. The second part is devoted to application of machine learning in management information systems. The third part presents problems related to multiple criteria decision analysis and computational methods. The book has an interdisciplinary character; therefore, it is intended for a broad scope of readers, including researchers, students, managers, and employees of business organizations, software developers, IT, and management specialists.

This book facilitates understanding of how artificial intelligence (AI) aids and integrates digital transformation (DT) in education institutions worldwide in various scenarios: learning environments (learning innovation, learning management systems, data and analytics), emerging education trends (business trends, strategic technologies), administrative systems (recruit, retain, advance, enterprise business capabilities, student information systems), and digital strategy execution (business models and opportunities, strategic planning and governance). It serves as a reference for university lecturers, schoolteachers, policymakers, and international organizations, who will find in its various chapters practical recommendations and discoveries from practice, ready to be implemented in their contexts. Chapters 1, 2, 7 and 9 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

In an era of rapid technological change and growing uncertainties, this book equips managers and engineers with vital risk management tools. Addressing challenges such as pandemics, supply chain disruptions, and political tensions, it blends qualitative and quantitative approaches to modern risk management. The first half explores enterprise risk management, including business continuity, compliance, and crisis management. The second half focuses on quantitative methods, featuring a mathematical bootcamp on probability, statistics, and Monte Carlo simulations, with detailed case studies. Designed for beginners and intermediate professionals, it also benefits students seeking a comprehensive overview of risk management. The book draws on the author's extensive experience as a manager, trainer, and auditor, offering practical, tested solutions. While tailored to the needs of SMEs, the concepts are applicable to all organizations. This book stands out for its balanced treatment of both qualitative and quantitative aspects, providing numerous examples and complete solutions for practice.

This book constitutes the proceedings of the 17th International Conference on Informatics in Schools: Situation, Evolution and Perspectives, ISSEP 2024, held in Budapest, Hungary, during October 28–30, 2024. The 14 full papers presented were carefully reviewed and selected from 42 submissions. The papers cover the following topics: curricula and computer science concepts; problem solving, algorithms and programming; teacher's perspective.

This unique book covers a wide spectrum of neurosurgical science and practice. Authored by world-renowned neurosurgeons, it aims to bridge the gap between practical anatomy and the recent advances in neurosurgical interventions. A special section on neurovascular surgery demonstrates the surgical skills required and challenges faced during surgery of complex aneurysms, vascular malformations and options for special revascularization procedures. Distinctive chapters highlight the anatomical landmarks for tailored microsurgical and endoscopic approaches to skull base, ventricular and spinal tumors. This textbook outline the role of white matter dissection in glioma and epilepsy surgery with an update on functional and peripheral nerves neurosurgery and a special chapter on the anticipation and management of complications in adult and paediatric neurosurgery.

The 2024th edition of Robotics in Education is based on the 15th Conference on Robotics in Education (RiE2024) mirroring experts'knowledge from all over the world. It includes and summarizes all accepted papers from an interdisciplinary community, which met traditionally at the annual Robotics in Education conference making it a valuable resource for educators, researchers, scientists and engineers. Without losing the focus on educational robotics, the topics have been carefully expanded this year. Therefore, the contributions ranges from theory to practice and from primary schools to university labs while the content covers experience reports from out of school programs to didactic-methodological approaches in teacher training and artificial intelligence to human robotics interaction. Also new robot designs, robot competitions and aspects of maker spaces were considered. The anniversary edition of the conference took place from 10.-12. April 2024 at the University of Koblenz in Germany.

This volume constitutes poster papers and late breaking results presented during the 25th International Conference on Artificial Intelligence in Education, AIED 2024, which took place in Recife, Brazil, during July 8–12, 2024. The 18 full papers and 92 short papers were carefully reviewed and selected from 200 submissions. They are organized in topical sections as follows: Part One: Blue Sky, Industry, Innovation and Practitioner, WideAIED and Late-Breaking Results. Part Two: Late-Breaking Results, Doctoral Consortium, Workshops and Tutorials.

This book serves as an introduction to the growing field of quantum many-body transport in interacting nanojunctions. It delves into a theoretical approach based on a general density-matrix formulation for open quantum systems. In the book, relevant transport observables, like the current or its higher order cumulants, are obtained by evaluating quantum statistical averages. This approach requires the knowledge of the reduced density matrix of the interacting nanosystems. The formulation for addressing transport problems, based on the evolution of the reduced density operator in Liouville space, is highly versatile. It enables the treatment of charge and spin transport across various realistic nanostructures. Topics encompass standard Coulomb blockade, cotunneling phenomena in quantum dots, vibrational and Franck-Condon effects in molecular junctions, as well as many-body interference observed in double quantum dots or carbon nanotubes. Derived from lectures tailored for graduate and advanced students at the University of Regensburg in Germany, this book is enriched with exercises and step-by-step derivations.

Dieses Buch richtet sich an Lehrende und Lernende aus den Gesundheitsberufen und zeigt die vielfältigen Chancen digitaler Technologien und Strategien für den Lehr- und Lernprozess. Durch den passenden Einsatz digitaler Formate werden Methoden gezielt weiterentwickelt und die Qualität der Lehre gesteigert. Welche Methoden und Formate gibt es und für welche Lernsituationen eignen sie sich konkret? Welche Möglichkeiten bieten sie für die Umsetzung und Unterrichtsgestaltung? Wie erzielen die Studierenden im digitalen Lernkontext Lernerfolge? Digitale Kompetenzen und deren didaktische Dimensionen sowie Aufbaumöglichkeiten werden explizit im Buch beschrieben und anwendungsnah aufbereitet.

This book covers several cutting-edge topics and provides a direct follow-up to former publications such as “Intent-based Networking” and “Emerging Networking”, bringing together the latest network technologies and advanced AI applications. Typical subjects include 5G/6G, clouds, fog, leading-edge LLMs, large-scale distributed environments with specific QoS requirements for IoT, robots, machine and deep learning, chatbots, and further AI solutions. The highly promising combination of smart applications, network infrastructure, and AI represents a unique mix of real synergy. Special aspects of current importance such as energy efficiency, reliability, sustainability, security and privacy, telemedicine, e-learning, and image recognition are addressed too. The book is suitable for students, professors, and advanced lecturers for networking, system architecture, and applied AI. Moreover, it serves as a basis for research and inspiration for interested professionals looking for new challenges.

This book unpacks key concepts and methods relevant for a critical and reflective framing of futures in postdigital education. The compiled chapters explore concepts and methods that have pertinence for contemporary debates about the emergence of data-driven education and scrutinize implicit or explicit ethical and normative implications. The book provides in-depth critical reflections and perspectives to engage and analyze data-driven education as an educational and cultural phenomenon. It focuses on the value-laden and ethical aspects reflected in educational imaginaries (discourses and practices) regarding emerging data-driven sociotechnical practices in education. The book is the result of scholarly exchanges between disciplines at a symposium held at VIA University College in Denmark in May 2022.

Minimieren Sie Ihre Risiken mit klinischem Risikomanagement.Klinisches Risikomanagement und Patientensicherheit sind unverzichtbare Bestandteile ärztlichen und pflegerischen Handelns.Experten erläutern Grundlagen, zeigen praktische Lösungen und stellen Werkzeuge vor wie: Checklisten, Standard Operating Procedures, Critical Incident Reporting-Systeme, Mortalitäts- & Morbiditäts-Konferenzen, Peer Reviews, Ursachenanalysen wie dem London Protokoll, Simulationen und Szenarioanalysen, Einsatz von Qualitätsindikatoren und Patientensicherheitsindikatoren sowie Risiko-Audits. Erfassen und bewerten Sie Risiken mit Qualitäts- und Patientensicherheitsindikatoren unter Verwendung anerkannter Risikomanagementnormen wie der ISO-Norm 31000. Das vollständig überarbeitete und erweiterte Handbuch deckt Themen ab wie: Führung, Strategieentwicklung, Teamentwicklung, Mitarbeitermotivation, Organisationales Lernen, Etablierung einer Sicherheitskultur. Und greift aktuelle Themen wie Digitalisierung, neueste Human Factor-Forschungen und die Rolle der Architektur für Patientensicherheit auf.Es werden sowohl medizinische, managementbezogene, ökonomische, psychologische, juristische als auch technische Themen angesprochen, um den Lesern alles an die Hand zu geben, um ein effizientes Risikomanagement - am eigenen Bedarf orientiert - zu implementieren. Es richtet sich an Entscheidungsträger und Führungskräfte sowie an die vielen Umsetzer vor Ort, wie Geschäftsführer, Ärztliche Direktoren, Pflegedirektoren, Chefärzte, Oberärzte, Pflegedienstleitungen, Stationsleitungen, Risikomanager, Patientensicherheitsbeauftragte, Qualitätsmanager- und -beauftragte, Personalmanager, Hygienemanager und -beauftragte, IT-Führungskräfte, Apotheker, Medizintechniker, Bautechniker, Krisenmanager und Juristen.

This book shows how modern risk management in banks and insurance companies can be modeled in Excel and Matlab. Readers are provided with all the necessary knowledge and skills in a systematic and structured step-by-step manner. Apart from basic Excel knowledge, no previous knowledge is required. The textbook is divided into five parts. First, the reader learns the basics of analyzing and modeling market risks. Next, the authors introduce and explain the modeling of credit risks and operational risks are quantified by calibrating loss distributions based on expert estimates. Furthermore, individual risk measures are examined in more detail. In order to calculate a risk measure for an overall portfolio to determine the risk capital, the question of the aggregation method is discussed. There are various common concepts for this, which are examined in more detail in the last part of the book.The book is aimed at students of business administration with a focus on financial services. Accompanying the book, readers receive Excel spreadsheets as digital bonus material for practice and application.

This clinical atlas is a comprehensive reference work on bone and joint disorders that can be characterized and assessed with hybrid bone SPECT/CT. It is structured according to the major joints and regions of the skeletal system, including spine, shoulder and elbow, hand and wrist, pelvis and hip, knee, and foot and ankle. For each region, the annotated normal X-ray and cross-sectional anatomy is presented, followed by a general introduction to the most common pathologies and frequent surgical procedures. Optimal bone SPECT/CT acquisition parameters are summarized and pre- and postoperative conditions are then discussed with the aid of informative clinical case vignettes featuring not only bone SPECT/CT images but also correlative findings on other imaging modalities. For every case, teaching points highlighting need-to-know findings and common pitfalls are presented. The book concludes with two dedicated chapters covering bone SPECT/CT imaging in sports injuries and oncology. Featuring many high-quality illustrations, Clinical Atlas of Bone SPECT/CT will be an invaluable resource for all nuclear medicine physicians. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

This two-volume set, LNCS 15346 and LNCS 15347, constitutes the proceedings of the 25th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2024, held in Valencia, Spain, during November 20–22, 2024. The 86 full papers and 6 short papers presented in this book were carefully reviewed and selected from 130 submissions. IDEAL 2024 is focusing on Big Data Analytics and Privacy, Machine Learning & Deep Learning for Real-World Applications, Data Mining and Pattern Recognition, Information Retrieval and Management, Bio and Neuro-Informatics, and Hybrid Intelligent Systems and Agents.

For some years now, the automation of any number of processes and process steps using RPA technology has been keeping the financial sector busy. It has now become an integral part of everyday life in many business areas. How does the technology work, who is responsible and what are the risks of using it in your own bank? This book answers these and many related questions about RPA, which are asked in particular by internal and external auditors, but also by decision-makers. In addition to an introduction to the technology and its classification in a broad, strategic context, the topic of the correct'auditing and assessment'of the technology is discussed.

This book constitutes the refereed proceedings of the 7th International Conference on Computer Science and Mathematics, CMSC 2024, held in Trier, Germany, during October 7–10, 2024. The 17 full and short papers included in this book were carefully reviewed and selected from 26 submissions. They were organized in topical sections as follows: Invited Papers; Tactile Learning: Unplugged Graphs, Trees, and Patterns; Teaching Advanced Concepts Using Tangible Machines; Curricular Desicion-Making; Computational Thinking and Interdisciplinary Instruction; Innovative Teaching Beyond the Classroom.

This book provides an interdisciplinary concept of digital working environments in industry 4.0 to enable the implementation of the digital twin of humans.Information and communication technology is penetrating all areas of daily life at a rapid pace in private and professional areas. These technologies enable companies to aggregate huge volumes of data. Collected personal data of employees creates the opportunity of a digital representation of the human being itself, that is conformant with the definition of a digital twin. These digital twins of humans include selected characteristics and behaviour of the humans, that are linked to models, information, and data. According to existing trend studies, the digital twin of humans is a technology that will have a significant impact on the economy, society, and people. It is important to consider the regulatory framework for the use of personal data and threats of misuse.This book will be of use to researchers and professionals in industry.

This book presents a collection of meta-studies, reviews, and scientometric analyses that together reveal a fresh picture about the past, present, and future of computing education research (CER) as a field of science. The book begins with three chapters that discuss and summarise meta-research about the foundations of CER, its disciplinary identity, and use of research methodologies and theories. Based on this, the book proceeds with several scientometric analyses, which explore authors and their collaboration networks, dissemination practices, international collaboration, and shifts in research focus over the years. Analyses of dissemination are deepened in two chapters that focus on some of the most influential publication venues of CER. The book also contains a series of country-, or region-level analyses, including chapters that focus on the evolution of CER in the Baltic Region, Finland, Australasia, Israel, and in the UK & Ireland. Two chapters present case studies of influential CER initiatives in Sweden and Namibia. This book also includes chapters that focus on CER conducted at school level, and cover crucially important issues such as technology ethics, algorithmic bias, and their implications for CER.In all, this book contributes to building an understanding of the past, present and future of CER. This book also contributes new practical guidelines, highlights topical areas of research, shows who to connect with, where to publish, and gives ideas of innovative research niches. The book takes a unique methodological approach by presenting a combination of meta-studies, scientometric analyses of publication metadata, and large-scale studies about the evolution of CER in different geographical regions. This book is intended for educational practitioners, researchers, students, and anyone interested in CER. This book was written in collaboration with some of the leading experts of the field.

This book contains the revised selected, refereed papers from the IFIP World Conference on Computers in Education on Towards a Collaborative Society through Creative Learning, WCCE 2022, Hiroshima, Japan, August 20-24, 2022. A total of 61 papers (54 full papers and 7 short papers) were carefully reviewed and selected from 131 submissions. They were organized in topical sections as follows: ​ Digital Education and Computing in Schools, Digital Education and Computing in Higher Education, National Policies and Plans for Digital Competence.

This book constitutes the proceedings of the 16th International Conference on Informatics in Schools: Situation, Evolution and Perspectives, ISSEP 2023, held in Lausanne, Switzerland, during October 23–25, 2023. The 14 full papers presented in this book were carefully reviewed and selected from 47 submissions. They are organized in four topical sections named: artificial intelligence and its applications; competitions, problem solving, and computational; robotics and unplugged modalities; and curricula and computer science concepts. This is an open access book.

Nichts im Leben und im Projektmanagement geht genau nach Plan. Immer wieder machen uns äußere Ereignisse und Entwicklungen einen Strich durch die Rechnung. Deshalb ist die nüchterne Analyse von Risiken und die Vorbereitung auf entsprechende Krisen ein Schlüsselelement erfolgreichen Projektmanagements. Dem stehen jedoch psychologische Faktoren entgegen. Welche Faktoren dies sind und woher diese kommen und wie man damit umgeht, darauf gibt es Antworten in diesem Buch und dem inkludierten Online Kurs.

This book shares with an international audience of teachers, scholars, and policymakers the experience of pedagogical practices to facilitate sustainability in the world. Sustainability is seen here as a journey toward the end state of sustainable development. Therefore, the authors contribute different roads to engage teachers and students with pedagogical discourse. Overall, the book demonstrates the value of powerful knowledge through action-oriented learning based on a bottom-up process. Consequently, pedagogical practices are understood as the instructional approaches based on a social constructivist model in which active learning is performed with student-to-student engagement. Secondary teachers in social sciences and university professors in geography find the study to be a valuable source of stimulation for incorporating new ideas and resolving common problems in their learning and teaching environments. Education policymakers around the world also benefit from the only publication that presents international perspectives on geographical knowledge related to sustainability.The contributing authors are experienced scientists in the field of geography education who are giving special attention to pedagogical practices that promote new directions toward sustainable thinking.This book is the first outcome of an international collaboration officially established in 2023 between the Department of Geography and Environmental Studies at Texas State University and the Department of Geography at the University of Bayreuth.

This reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression, formation, and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering, including CRISP/Cas9, in designing and developing animal models for cancer research. Further, it discusses strategies for modeling animals for investigating growth, metastasis, tumor-associated inflammation and microenvironment, cancer stem cells, tumor heterogeneity, and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers, clinicians, and health care.

Education is the cornerstone of any society; it serves as one of the foundations for many of its social values and characteristics. mis4TEL'23 promotes the interaction among the scientific community to discuss applications of Technology Enhanced Learning solutions targeting not only cognitive and social processes but also motivational, personality, or emotional factors. In addition, current trends concerning the use of artificial intelligence can help and augment learning opportunities for learners and educators. The 13th International Conference on Methodologies and Intelligent Systems for Technology Enhanced Learning (mis4TEL'23) technical program includes 26 contributions (13 full papers and 13 short papers). mis4TEL'23 is hosted by the LASI and Centro Algoritmi of the University of Minho (Portugal). The authors would like to thank all the contributing authors, the members of the Program Committee, National Associations (AEPIA and APPIA), and the sponsors (AIR Institute and Camara Municipal de Guimarães).

This book summarizes the state-of-the-art advances in the area of computational modelling of molecule-based magnets. Nowadays, various computational tools based on DFT, ab initio methods and other techniques are gaining attention in molecular nanomagnets and are successfully used to solve several outstanding problems in this area. This contributed volume discusses the theoretical foundation of the modelling of molecular magnets, starting from fitting the experimental magnetic data of very large molecules to the theory of pseudo-spin Hamiltonian approach and spin-phonon relaxations mechanisms, while it also presents examples of contemporary applications of both transition metal and lanthanide molecular magnets. In addition, the transport characteristics of molecules when placed at an interface and how these assemble on surfaces are also reviewed. This book is a great tool for researchers working in the fields of molecular magnetism and computational/theoretical chemistry and will also benefit graduate students specializing in physical-inorganic chemistry and molecular modelling.Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

We are currently witnessing a significant transformation in the development of education on all levels and especially in post-secondary education. To face these challenges, higher education must find innovative ways to quickly respond to these new needs.These were the aims connected with the 25th International Conference on Interactive Collaborative Learning (ICL2022), which was held in Vienna, Austria, from September 27 to 30, 2022.Since its beginning in 1998, this conference is devoted to new approaches in learning with a focus on collaborative learning in higher education.This book contains papers in the fields of:•Collaborative Learning•Digital Transition in Education•Technology Enhanced Learning•Advances in Machine and Technology Enhanced Learning•Educational Virtual Environments•Flipped Classrooms•Games in Engineering Education•Entrepreneurship in Engineering EducationInterested readership includes policymakers, academics, educators, researchers in pedagogy and learning theory, school teachers, the learning industry, further and continuing education lecturers, etc.

This book contains highly effective ways to teach coding and computational thinking skills throughout primary and secondary schooling. It outlines a research informed path for students from birth to 18 years, identifying key skills and learning activities. Based on global perspectives and research at each stage, it outlines how these findings can be applied in the classroom. Teaching coding to students in K-12 has been a skillset that has been debated across educational jurisdictions globally for some time. The book provides examples of schools that are teaching coding to students in engaging and relevant ways, delivering well thought out compulsory curriculums. Additionally, it provides examples of schools where coding is not mandated in the curriculum and is taught in an ad-hoc manner. Through the full discussion of all of these varied examples, the book presents both sides of the serious and ongoing debate in the field as to whether coding should be taught in an explicitway at all. The increasing school of thought that teaching coding is a skill that is already obsolete, and the focus should be on computational thinking is completely examined and presented. In this book, both sides of the argument, as well as the specific, meticulous research underlying each side, are given equal weight. The debate is a serious one and requires a clearly defined thematic response with evidence on all sides of the argument presented rationally. This book does just that. Created by carefully selected authors from around the world, it will be a highly studied research reference.

Das vorliegende Fachbuch beschreibt umfassend die multidisziplinäre Versorgung komplexer Defekte im Kopf-Hals-Bereich. Autoren verschiedener, in der Kopf-Halschirurgie tätiger Fachdisziplinen zeigen klinische Problemstellungen und ihre chirurgischen Lösungen aus unterschiedlichen Blickwinkeln auf. Die infrage kommenden Lappenplastiken werden detailliert beschrieben und interdisziplinär dargestellt.Eine Vielzahl von intra- und perioperativen Fotos, sowie systematischen Zeichnungen tragen zur besseren Visualisierung der Vorgehensweisen bei.

This book provides insights from research and practice in how organizations were able to sustain resilience in their global supply chains during the COVID-19 pandemic and to advance the understanding of supply chain risk management. The chapters highlight the lessons learned, insist on new models for resilience, suggest improved supply chain risk methodologies and bridge the gap between research and practice. It helps readers acquire greater knowledge, strategic approaches, new methods, and practical tools for ensuring global supply chain resilience.

This volume constitutes poster papers and late breaking results presented during the 24th International Conference on Artificial Intelligence in Education, AIED 2023, Tokyo, Japan, July 3–7, 2023.The 65 poster papers presented were carefully reviewed and selected from 311 submissions. This set of posters was complemented with the other poster contributions submitted for the Poster and Late Breaking results track of the AIED 2023 conference.

Data has become an indispensable success factor for every company. However, the road towards a data-driven organization is paved with numerous challenges. This book presents a process model for the path to a data-driven company and provides recommendations for the design of all relevant fields of action: Which structures need to be created? Which systems and processes have proven beneficial? How can the quality of the data be ensured and what requirements exist for a data-driven organization in the areas of governance and communication? And last but not least: How can employees be brought along on the journey and what implications does the data-driven organization have for our corporate culture? The book presents an orientation and action framework for the strategic and operational design of a data-driven organization and is valuable for managers who are involved in data management in companies and organizations.

This book constitutes the refereed proceedings of the 46th German Conference on Artificial Intelligence, KI 2023, which took place in Berlin, Germany, in September 2023.The 14 full and 5 short papers presented were carefully reviewed and selected from 78 submissions. The papers deal with research on theory and applications across all methods and topic areas of AI research.

Planning and reporting solutions in many companies still suffer from poor data quality, are insufficiently integrated and are often time and cost intensive. This practice-oriented book shows step by step how things can be done differently. It systematically shows how modern planning and reporting systems in BI-supported controlling can be set up with the use of data warehouse and big data technology and usefully supplemented with AI-supported features. For the 4th edition, the book has been comprehensively updated. The extensive controlling cockpit example has been expanded. It now contains suggestions for the areas of corporate management (operational and strategic controlling), sales, production, purchasing and project management. In addition, the latest developments in BI-supported controlling with the support of traditional and explorative BI are highlighted, including data mining, predictive analytics, artificial intelligence, RPA, chatbots, data discovery, data visualization, app technology, self-service BI and cloud computing. Further innovations concern the topics of data quality and data modeling. The final chapter is'Mobile BI', which deals with the expansion of powerful mobile analysis and planning solutions with the help of tablets, mobile phones and other mobile devices.

Sustainable finance is a holistic approach to the sustainability development goals (SDG), so that the interdependence between environmental, social, and governance issues is unveiled. Sustainable finance takes into account the various challenges following from social change and sustainability, the evolution of capital markets, and the development of efficient risk management practices. Governance issues are an integral part of sustainable finance. However, academic literature has generally neglected to consider strategies to prevent and fight financial crimes as a crucial component of sustainable finance. The aim of this book is to focus on the interconnectedness between sustainable finance and preventing/fighting financial crime, not only as a crucial governance issue, but also as a deep challenge for social and even environmental issues. There is no really sustainable finance without developing strong and efficient means to fight financial crimes.

This book provides an overview of a wide range of relevant applications and reveals how to solve them. Many of the latest applications in finance, technology, education, medicine and other important and relevant fields are data-driven. The volumes of data are enormous. Specific methods need to be developed or adapted to solve a particular problem. It illustrates data science in applications. These applications have in common the discovery of knowledge in data and the use of this knowledge to make real decisions. The set of examples presented serves as a recipe book for their direct application to similar problems or as a guide for the development of new, more sophisticated approaches. The intended readership is data scientists looking for appropriate solutions to their problems. In addition, the examples provided serves as material for lectures at universities.

This book is conceptualized as being of interest to researchers in the field of sustainable transport, and also those who are working in the field. In the first case it will provide a reference on the state of the art of sustainable transport, and will also include insights into an EU project, how to go about delivering impact, how such projects effect local authorities, etc. Sustainable transport is an extreme growth area; it is highly innovative, with multi-million-pound investments transforming cities. The book will help and encourage resource poor small to medium local authorities catch up and meet their sustainability targets.

Das Fachbuch bietet Orientierungshilfe bei der Analyse der Kompetenzanforderungen im Digitalen Wandel. Es stellt Kompetenzmodelle unterschiedlicher Ausrichtungen vor und dient als Ausgangsbasis für die Profilbildung in der eigenen Organisation. Schwerpunkte sind Computational Thinking, Informationskompetenz, Künstliche Intelligenz und ethische Reflexion.Die Anforderungen dienen als Basis für die Konzeption einer passgenauen Kompetenzentwicklung für den Digitalen Wandel. Anschaulich präsentierte Anwendungsbeispiele regen die Umsetzung innovativer Maßnahmen im Umfeld der eigenen Organisation an.Der InhaltMit Kompetenzmodellen digitalisierungsbezogene Bildungserträge erfassen und fächerübergreifend konzipierenMit Kompetenzmodellen spezielle Aspekte des Digitalen Wandels vertiefenMit Kompetenzmodellen die kritische Reflexion des Digitalen Wandels fördernMit Kompetenzmodellen ausgewählte Bildungsszenarien gestaltenDie ZielgruppenBildungsmanager/-innenPersonalmanager/-innenLehrkräfteFührungskräfteStudierendeEhrenamtlich Engagierte