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This book delves into total laparoscopic hysterectomy (TLH), covering a range of intricate situations like multiple previous surgeries, severe endometriosis, frozen pelvis, large masses, and multidisciplinary surgeries. It specifically emphasizes on the posterior approach and the comprehensive canopy concept for dissecting densely adherent bladder in TLH. Each chapter provides numerous high definition, 4K, surgical snapshots in an easy-to-understand language, aiming to simplify surgical techniques. Most chapters have been provided with procedural videos to further enhance the clarity, thus making complex TLH safer, simpler, and more accessible to surgeons. The book is relevant for budding and experienced surgeons alike and for practitioners of minimally invasive surgery.

More than 100 years ago, Dr Casimir Funk suggested the existence of a family of organic substances that are essential for life and thus introduced the concept of “vital amines” as essential nutrients with a specific action, requiring only minute amount with the power to cure a specific disease. Vitamins essential for human health are grouped according to whether they are soluble in water (hydrophilic) or in non-polar solvents (lipophilic). The hydrophilic vitamins are vitamin C and a series known as the vitamin B complex. Vitamin C is a reducing agent, whereas the vitamin B series are components of coenzymes. For example, riboflavin (vitamin B2) is a precursor of flavin adenine dinucleotide (FAD) and pantothenate (vitamin B5) is a component of coenzyme A. Indeed, several coenzymes contain a vitamin as part of their structure; this relation is undoubtedly responsible for creating an “essential” role for the vitamin. Since vitamins are involved in a wide range of biological processes and cell function, these are considered as essential nutrients. The essential nature of vitamins as well as their unique biochemistry, molecular mechanisms and cellular function in health and disease are emphasized in this book which will serve as a highly useful resource for health professionals, nutritional scientists, medical students, fellows, residents, and graduate students.

Sex/gender-specific medicine (SGM) is defined as the practice of medicine based on the understanding that biology and social roles are important in men and women for prevention, screening, diagnosis, and treatment. Current research demonstrates differences in disease incidence, symptomatology, morbidity, and mortality depending on sex and gender. Sex/gender-specific medicine is a fundamental aspect of tailored therapy and precision medicine. Therefore, the variables must be considered in medical education and practice as well as in research models ranging from human participants, animals and cells. This concept could be applied in the whole clinical areas from Neuroscience, Psychiatry, Gastroenterology, Cardiology, and Rehabilitation, etc. Nowadays estrogen is known to play a key role in the prevention of colon cancer and in the resistant progression of liver cirrhosis and hepatocellular carcinoma, especially in women. This book covers the sex/gender-specific medicine in the whole clinical areas in the adults as well as in the pediatrics. In addition, research results of basic science are also introduced in the colon cancer and Alzheimer's disease.

This book offers an authoritative and comprehensive overview of the wide range of surgical procedures and non-invasive options for the male cosmetic and reconstructive patients. Chapters examine the full gamut of unique male aesthetic and reconstructive surgical procedures, written by an interdisciplinary team of well-known and well-respected national and international contributors. The book provides an up-to-date and highly illustrated coverage of existing techniques and innovative, new technologies. Chapters relay the interplay between the unique male anatomy, expectations, clinical implications, therapeutic gems and approach to men seeking aesthetic enhancements. Each chapter highlights a concise but comprehensive description of the clinical issue augmented by appropriate illustrations, related art works, and videos. When applicable, an interdisciplinary style utilizing the expertise of allied specialties such as dermatology, facial plastic surgery, and oculoplastic surgery are utilized.Chapters address key issues and areas not previously included in other books, such as:Direct excision of nasolabial folds and submental regionFacial rejuvenation and other aesthetic procedure available to people of colorSurgery for body buildersBuried penisManagement of hyperhidrosisHIV: facial wasting and buffalo humpA Comprehensive Guide to Male Aesthetic and Reconstructive Surgery is a must-have resource for plastic and reconstructive surgeons to successfully manage the distinctive, unique needs of the male patient.

This book focuses on menstrual cycle bleeding and pain disorders from menarche to menopause. Hormonal and tissue basis of menstrual cycle are described as well as the role of ultrasound in the evaluation of normal and abnormal endometrium and sex steroid hormones used in the treatment of such disorders. How to identify patients with coagulation disorders, the correlation of AUB in early menarche and PCOS later in adolescence and adolescent menorrhagia are extensively analysed for their clinical and therapeutic implication.Anovulatory syndromes and luteal phase defects are explained for their pathogenesis and role in women health. Dysmenorrhea and other pain syndromes as well PMS and PMDD are analysed for their diagnosis and management and the impact of endometriosis, adenomyosis and uterine myoma for the linkage of these organic diseases, inflammation and bleeding and pain disorders related to menstrual cyclicity. Endometrial hyperplasia and malignancy are also extensively examined for their pathogenesis, symptoms and role in uterine bleeding and pelvic pain as well as how to face oncological therapies induced amenorrhea. The last part of the book analyses and discuss the causes of menorrhagia in menopausal transition and the management of bleeding disorders under menopause hormone therapy.Written by experts in the field, this book will be of benefits to residents, general practitioners and specialists, gynaecologists, endocrinologists, paediatricians and GPs who deal with women's health care.

This book describes the most important contributions of Italian astronomers to the development of planetary astronomy during the nineteenth century and the early part of the twentieth century. This journey through what may be regarded as the golden era of Italian astronomy commences with the discovery of Ceres, the first asteroid, now classified as a dwarf planet, and culminates in the role played by the Padua Observatory in calculating Pluto's orbit in the 1930s. Along the way, a wealth of information is provided on the discovery of many comets and asteroids, early spectroscopic observations, drawings of planets and comets, calculations of orbits and ephemerides, and much more. The contributions of such famous figures as Giovanni Schiaparelli, Giovanni Battista Donati, Angelo Secchi, and Annibale De Gasparis are fully explained. Many of the described results are still of interest for modern astronomy, and the book appeals to a wide readership, including scholars, historians, astronomers, and the general public.

The successful book of andrology now in a new edition! This book gives a complete, interdisciplinary overview of the central topics of andrology, infertility, hypogonadism, contraception and erectile dysfunction. It contains detailed information on the clinical practice of couple treatment, andrology-relevant gynecology and modern methods of assisted fertilization, psychological factors of infertility, endocrinology and reproductive functions of the aging man as well as on an important sub-area of ​​andrology, the male contribution to contraception. In addition, the relevant scientific foundations (including molecular biology and genetics) are also covered. Completely revised and updated according to the latest scientific research, the new edition represents a reference for andrology, which no doctor who deals with the topic can miss. For andrologists, practitioners and residents, urologists, dermatologists and internists who deal with the area of​​andrology and male reproductive medicine.

This graduate textbook provides comprehensive information on topological analysis in real space of the electronic structure. Application of the topological tools is becoming routine for understanding the outcome of quantum chemical calculations. This title thoroughly reviews a selection of currently available topological tools, their use and spectrum of applications and provides graduate students and researchers with information not easily obtained from the available textbooks. The book is accompanied by worked examples, exercises and solutions and is a great tool for any quantum chemistry or computational chemistry course at the graduate and advanced undergraduate levels.

Das Standardwerk der Andrologie - jetzt komplett aktualisiert! Das Buch gibt einen vollständigen, interdisziplinären Überblick aller Themen der Andrologie, u.a. · der Infertilität, · des Hypogonadismus, · der männlichen Kontrazeption, · der erektilen Dysfunktion und · der Varianten der sexuellen Differenzierung. Der Leser erhält detaillierte Informationen über · die Physiologie der Hoden- und Spermienfunktion · die Diagnostik und Therapie einschl. operativer Verfahren in der Andrologie · die klinische Praxis der Paarbehandlung, · relevante Fakten aus der Gynäkologie, · moderne Verfahren der assistierten Fertilisation · psychologische Faktoren der Sexualität und Infertilität · Umwelteinflüsse auf die Fertilität · Therapie mit Testosteron und Missbrauch · endokrinologische und reproduktive Funktionen des alternden Mannes. · Fertilitätsprotektion · rechtliche und ethische Grundlagen der Andrologie Zusätzlich werden die relevanten naturwissenschaftlichen Grundlagen – einschließlich Molekularbiologie und -genetik – abgedeckt. Komplett nach dem neuesten Stand der wissenschaftlichen Erkenntnis überarbeitet, aktualisiert und praxisorientiert ist der Nieschlag das Standardwerk der Andrologie, an dem keine Ärztin und kein Arzt, der sich mit dem Thema befasst, vorbeikommt. Für Andrologen und Teilnehmer der Zusatzbezeichnung'Andrologie', Urologen, Dermatologen und Internisten, die sich mit dem Gebiet Andrologie beschäftigen. Für Reproduktionsbiologen und Reproduktionsmediziner mit Interesse an der Paarbehandlung.

This third of three related volumes is structured in 3 sections and 46 chapters covering every aspect of Hair Restoration Surgery (HRS), alternative and future treatments for AGA/FPHL, as well as hair loss concealment and hair care. The reader will find dedicated chapters on every aspect of HRS: from the initial,'prehistoric'HRS techniques that have cosmetically stigmatized countless patients and defamed the field to in-depth coverage of all modern HRS techniques endorsing a'cosmetic revolution'. Modern HRS techniques that offer results indistinguishable from natural hair in male and female patients are described in detail, with invaluable surgical pearls and strategies on how to treat complications, repair substandard results and even how to build a successful HRS practice. Chapters include more than a thousand original and unique full-color photos of unique cases, figures, tables, and invaluable surgical tips. The safety and applicability of Low Level Laser Therapy, Genetic Engineering/Gene Therapy, Stem Cell Therapy, Hair Follicle Cloning, Platelet Rich Plasma, Scalp Microneedling and Exosomes on AGA/FPHL are thoroughly reviewed in dedicated chapters, validated by several updated and balanced literature citations. All types of cover-up products that can'camouflage'baldness are reviewed in detail through the author's vast experience in their clinical use. An elaborate chapter on hair prosthesis and wigs illustrates how patients with extensive AGA can have a natural appearance and unrestricted life. The psychological entrapment, social awkwardness, hidden costs, and downsides of the wig industry are assessed. Finally, details on hair hygiene and how they can drastically affect hair loss are offered in a separate chapter. Handy, thorough, and practical, Androgenetic Alopecia From A to Z, Hair Restoration Surgery and Alternative Treatments Volume 3 will meet the needs of dermatologists, plastic surgeons, general practitioners, and all other physicians involved in this fast growing and fascinating field.

This book examines the nature, prevention, and treatment of violence within families. It reviews the definition of contemporary families, emphasizing various structures, including nuclear families, reconstituted families, gay and lesbian families, and recent immigrant families. In addition, the volume describes the nature of and risk factors for family violence from the perspectives of both victims (e.g., infants, children, seniors) and perpetrators (e.g., adolescent family members, women). It identifies the implications and explores strategies for prevention, treatment, and services. In addition, the volume directly addresses practice and evidence-based interventions for individual perpetrators, family interventions, interventions for victims and systemwide interventions (e.g., those involving the courts, police, and national policy). Chapters review the best available quality evidence from randomized controlled trials, systematic reviews, meta-analyses, research syntheses, and evidence-based recommendations from expert panels and government agencies. Case studies illustrate the application of evidence-based practice to violence within the family to demonstrate the effectiveness of the intervention. Topics featured in this book include:Definition and conceptualization of family.Definition and measurement of as well as risk factors for family violence.Family violence in various traditional and nontraditional families.Prevention strategies as well as Individual and family treatments for perpetrators and victims of family violence.Social policy and legal interventions for family violence. Violence in Families is a must-have resource for researchers, professors, and graduate students as well as clinicians, therapists, and other professionals in developmental psychology, family studies, forensic psychology, criminology/criminal justice, public health, psychotherapy/counseling, psychiatry, social work, educational policy and politics, health psychology, nursing, and behavioral therapy/rehabilitation.

Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications ofPCOS and by raising awareness of potential “ripple effects”, aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS (including but not limited to reproductive endocrinologists, gynecologists, family physicians, dermatologists, mental health professionals), for the aspiring women's health providers of tomorrow, and for the researchers who are striving to unravel the mysteries of the complex entity that PCOS is.

This reference volume conveys complete understanding and management of Androgenetic Alopecia and Female Pattern Hair Loss (AGA/FPHL). These are probably the most common adult (18-50 yrs.) health disorders besides dental caries, accounting for over 98% of hair loss cases in males and over 70% cases in females. The present volume, the first of three related volumes, is structured in 4 sections: 22 dedicated chapters, ranging from basic science (Biology, Anatomy, Physiology, Embryology), the etiology of adult, childhood & adolescent AGA/FPHL, diagnostic steps and evaluation, to related disorders and comorbidities. For the first time in the scientific literature, all pathogenic contributors of AGA/FPHL, including micro-inflammation, scalp vascularization, biochemical stress, aging, solar radiation, and the sebaceous gland, are examined in comprehensive, dedicated chapters. The effects of every hormone on AGA/FPHL, as well as the psychological impact of the condition, are explored in depth. An extensive chapter on childhood and adolescent AGA/FPHL, a more common than previously thought condition, is another unique feature. Finally, two extremely detailed sections are included on the pathogenic links of AGA/FPHL to life-threatening comorbidities: cardiovascular disease, metabolic syndrome, hypertension, insulin resistance, and prostatic disorders, with suggested guidelines on how to save lives of balding patients by adopting early screening strategies. In providing a fully updated, thorough guide to this popular topic, this richly illustrated volume (over 200 figures, tables, and algorithms) offers the latest, evidence-based information on every aspect of AGA/FPHL causing hair loss to countless patients. Each subject is addressed according to learning and clinical needs, and the presented information is supported by a wealth of peer-reviewed papers. Every aspect of this condition is considered, including biology, diagnosis, etiology, from drug treatment, the influence of nutrition, lifestyle and food supplements, to related disorders, surgical hair restoration, hair care, and future treatment options. This handbook will be an invaluable conveying best management standards to readers, whether experienced practitioners, clinicians, dermatologists, surgeons or researchers interested in hair restoration.

This book covers dermatological and related esthetic concerns specific to female patients. Since knowing what's normal is as important as knowing what's not, first chapters covers physiological differences in the skin of women and the changes during puberty, pregnancy, and menopause. Certain commonly encountered dermatoses are more frequent in females – chronic telogen effluvium, rosacea, perioral dermatitis, pigmented contact (cosmetic) dermatitis, etc., which are explained in a more focused manner. Dermatoses exclusive to females involving the vulva is discussed at length. These include common papulosquamous conditions such as psoriasis, lichen planus, and lichen sclerosus as well as the uncommon but challenging plasma cell vulvitis. Breast dermatoses also are predominantly encountered in women and are described in detail in this book. Importantly, the safety of drugs and biologics in pregnancy and lactation have been covered too. One section is dedicated to the emotional and psychological burden of skin disease in women and certain disorders requiring psychiatric intervention such as obsessive-compulsive disorder (trichotillomania, trichotemnomania) and body dysmorphic disorder. Furthermore, commonly used cosmeceuticals and frequently performed esthetic procedures such as chemical peels, botulinum toxin, and soft tissue augmentation (fillers) are well explained. Skin diseases in females can cause a significant emotional and psychological impact that can sometimes be more serious than the physical impact. There is a paucity of comprehensive published literature in both journal and books and this book aims to fill that gap. This book is meant as a resource for dermatology residents and trainees, practitioners, and teachers.

This encyclopedia, representing one of the most multi-disciplinary areas of research, is a comprehensive examination of the key areas in animal cognition and behavior. It will serve as a complementary resource to the handbooks and journals that have emerged in the last decade on this topic, and will be a useful resource for student and researcher alike. With comprehensive coverage of this field, key concepts will be explored. These include social cognition, prey and predator detection, habitat selection, mating and parenting, development, genetics, physiology, memory, learning and perception. Attention is also given to animal-human co-evolution and interaction, and animal welfare. All entries are under the purview of acknowledged experts in the field.

This encyclopedia volume covers the complete field of endocrine pathology – from Acidophil Stem Cell Adenoma to Waterhouse-Friderichsen syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

This third, thoroughly updated edition of a well received book, presents the most complete collection of theories, paradigms and methods utilized by the landscape sciences. With the introduction of new ecosemiotic concepts and innovative managing procedures, it offers a broad list of ecological, ecosemiotical and cultural tools to investigate, interpret and manage the environmental complexity according to a species-specific individual-based approach. Readers will discover the importance of a landscape perspective to create strategic bridges between science and humanities favored by the holistic sight of sensorial (visual, acoustic, olfactory, tactile, and thermal) “scapes”.Distributed in 10 chapters, the content covers many aspects of the landscape sciences ranging from the description of fundamental theories, principles and models originated by ecological approaches like source-sink models, island biogeography, hierarchical theory and scale. The ecosemioticalapproaches like the eco-field model, the ecoscape paradigm, and the general theory of resources are widely described and discussed. A cultural approach to landscape is utilized to focus on the heritage values of territories and their environmental identity. This book, written in an accessible and didactic style, is particularly dedicated to undergraduate and graduate students but also scholars in ecology, agroforestry, urban planning, nature design, conservation and remediation. Land practitioners, farmers and policymakers can use this book as an authoritative guide to better understand the function and role of environmental systems according to a social-economic integrated perspective.

This comprehensive, twelve volume reference work reflects the interdisciplinary influences on evolutionary psychology and serves as a major resource for its history, scientific contributors and theories.It draws on biology, cognitive science, anthropology, psychology, economics, computer science and paleoarchaeology to provide a multifaceted picture of behavioral adaptation in humans and how it adds to our academic and clinical understanding. Edited by a noted figure in evolutionary psychology, with many seminal and renowned contributors, this encyclopedia offers the full breadth of an area that is the forefront of behavioral thinking and investigation.

This book is aimed at primary care providers who care for the pediatric age group (general pediatrician, the PCP working with pediatric patients, and family medicine providers) with the goal of covering the endocrine differential diagnosis of common signs and symptoms of possible endocrine disease as well as appropriate initial laboratory evaluation and interpretation. While multiple pediatric endocrine textbooks exist, most of them are heavy in coverage of physiology and rare diseases, with less discussion of practical steps in evaluation and diagnosis. This book distinguishes itself through a very practical approach. The first section is organized by presenting signs and symptoms, the second section is organized by laboratory interpretation, and the third section provides summaries of common pediatric endocrine disorders. Chapters are concise, providing critical clinical information including clinical pearls, common diagnoses and important points inpatient counseling. Written by experts in the field, Endocrine Conditions in Pediatrics is a valuable resource that provides general pediatricians and other primary care providers with all of the information they need to provide superb patient care before transferring to a pediatric endocrinologist when necessary.

This book is an academic and practical guide to the diagnostic methods and management strategies for both common and rare scrotal diseases. Chapters focus on the normal anthropometric measures of the scrotum as a unique organ and the latest relevant advancements in the field. Techniques including scrotal reconstruction for congenital abnormalities, trauma, and cancer-related extirpation are all covered. Critical tools and methods related to aesthetics are also detailed. Emphasis is also placed on identifying common pitfalls and how to avoid them, ensuring that the reader is fully equipped to deal with a range of scenarios.Normal and Abnormal Scrotum describes how to approach diagnosing and managing the entire range of scrotal diseases, making it essential for all general practitioners, pediatricians, urologists, and pediatric and aesthetic surgeons who encounter these patients in their day-to-day practice.

This monograph is the result of eight years of bibliographical and field research concerning several behavioural ecology aspects of the Palaearctic falcons. For a while, this book grew along with “The Lanner falcon” published in 2015 and revised in 2017. In both books the main aim was to provide a clear overview of the biology and ecology of these species. In fact in the last 20 years, the number of publications on falcons has grown tremendously and, in parallel, also those belonging to the so-called'grey literature'. The number of people involved is also increased by including both academics and nature lovers. Many previously published books emphasized identification, and offered little insights on the behavioural and ecological aspects of the species. Very often, the research on behavioural ecology remains closed within the confines of academic community. By contrast, a multitude of basic data is scattered in countless articles published in local magazines. Many falcon species are easy to observe and study (such as kestrels) but others are more rare and localized. In order to understand the survival strategies adopted by this group of avian predators, it is necessary not to lose sight of the overall picture. This book tries to explain the different survival strategies by examining, through a few essential chapters, some crucial aspects for all species. The first chapter provides information on the genus Falco, its genetics, evolution and morphological peculiarities. The other chapters deal with reproductive strategies, competition, exploitation of resources, dispersal patterns, communication and sociality. One of the main objectives of this book is to produce an accessible but scholarly curated source of reference. By understanding the most common species, it is possible to provide a working framework for rarer, and especially threatened, falcon species.

This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material.Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge.This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

The book covers all relevant topics of uropathology (tumoral and non-tumoral), from the normal histology of the genitourinary tract to pathological findings of diseases in the male genital and urinary tract. To make the content more accessible, all content is arranged alphabetically and each entry is uniformly structured, presenting the epidemiology, the clinical signs, the gross and histological features, the immunohistochemical stainings, and the molecular data for each disease. Histological pictures clarify the microscopic findings and help readers understand the differential diagnosis for genitourinary tract diseases. In addition to internationally respected experts on pathologies of the prostate, bladder, kidney and testis, researchers coming from other disciplines such as molecular biologists, soft tissue pathologists, dermatopathologists, hematopathologists and gynaecopathologists have contributed to this book, thus making it interesting for uropathologists, but also for students, residents, clinicians (surgeons, radiotherapists, oncologists, urologists, dermatologists) and researchers who deal with disciplines that call for knowledge of the pathologies of the male genital and urinary tracts.

This book provides primary care clinicians, researchers, and educators with a guide that helps facilitate comprehensive, evidenced-based healthcare of women and gender diverse populations. Many primary care training programs in the United States lack formalized training in women's health, or if they do, the allotted time for teaching is sparse. This book addresses this learning gap with a solid framework for any program or individual interested in learning about or teaching women's health. It can serve as a quick in-the-clinic reference between patients, or be used to steer curricular efforts in medical training programs, particularly tailored to internal medicine, family medicine, gynecology, nursing, and advanced practice provider programs. Organized to cover essential topics in women's health and gender based care, this text is divided into eight sections: Foundations of Women's Health and Gender Based Medicine, Gynecologic Health and Disease, Breast Health and Disease, Common Medical Conditions, Chronic Pain Disorders, Mental Health and Trauma, Care of Selected Populations (care of female veterans and gender diverse patients), and Obstetric Medicine. Using the Maintenance of Certification (MOC) and American Board of Internal Medicine blueprints for examination development, authors provide evidence-based reviews with several challenge questions and annotated answers at the end of each chapter. The epidemiology, pathophysiology, evaluation, diagnosis, treatment, and prognosis of all disease processes are detailed in each chapter. Learning objectives, summary points, certain exam techniques, clinical pearls, diagrams, and images are added to enhance reader's engagement and understanding of the material. Written by experts in the field, Sex and Gender-Based Women's Health is designed to guide all providers, regardless of training discipline or seniority, through comprehensive outpatient women's health and gender diverse care.

This volume showcases the presentations and discussions delivered at the 2018 POMS International Conference in Rio. Through a collection of selected papers, it is possible to review the impact and application of operations management for social good, with contributions across a wide range of topics, including: humanitarian operations and crisis management, healthcare operations management, sustainable operations, artificial intelligence and data analytics in operations, product innovation and technology in operations management, marketing and operations management, service operations and servitization, logistics and supply chain management, resilience and risk in operations, defense, and tourism among other emerging Operations Management issues. The Production and Operations Management Society (POMS) is one of the most important and influential societies in the subject of Production Engineering and, as an international professional and academic organization, represents the interests of professionals and academics in production management and operations around the world.

This book is a richly illustrated account of the clinical features, microscopic anatomy, and management of acne, acne-like disorders, and rosacea. The coverage includes all aspects of these diseases, from physiology to pathology, bacteriology, and endocrinology; special emphasis is placed on histopathology. Moreover, the full spectrum of pharmacological and physical methods of controlling the disorders are critically examined and the widely experienced team of authors present in detail their personal strategies for successful treatment. Since it was first published, Acne and Rosacea has become a well-known classic. This fourth edition has been completely revised and updated, with entirely new chapters on topics such as etiopathogenesis, auto-inflammatory acne syndromes, the role of nutrition, and novel therapies. The text is supplemented by selected references and a wealth of clinical and histopathological pictures, including additional high-definition photographs. The book is designed for all those physicians – dermatologists, general practitioners, pediatricians, gynecologists, pharmacologists, and surgeons – who must identify and treat the many different forms of acne and rosacea.

This is the first book to offer a comprehensive yet concise overview of the challenges and opportunities presented by the use of big data in healthcare. The respective chapters address a range of aspects: from health management to patient safety; from the human factor perspective to ethical and economic considerations, and many more. By providing a historical background on the use of big data, and critically analyzing current approaches together with issues and challenges related to their applications, the book not only sheds light on the problems entailed by big data, but also paves the way for possible solutions and future research directions. Accordingly, it offers an insightful reference guide for health information technology professionals, healthcare managers, healthcare practitioners, and patients alike, aiding them in their decision-making processes; and for students and researchers whose work involves data science-related research issues in healthcare.

This book provides a comprehensive guide for nurses practicing in any area of endocrinology and at any level of expertise. Endocrinology Nursing is a fast-developing specialty with nurses performing advanced roles and expanding their practice to run independent nurse-led services. Supported by the European Society of Endocrinology (ESE) and edited by members of the ESE Nurses Working Group, this is the first book ever published specifically for endocrine nurses. It is also an excellent resource for endocrinology specialty trainees, general practitioners, medical and nursing students, expert patients and nurses working in specialties such as fertility, osteoporosis, oncology, obesity, urology and gynaecology, who look after patients with endocrine-related disorders. This volume includes 13 sections and 69 chapters providing a comprehensive overview of adult and paediatric endocrinology but also a section on advanced practice, role development and nursing research. It has been written by an international team of more than 100 eminent nurses, physicians, surgeons, psychologists and other healthcare professionals, which makes this book a valuable resource for any multidisciplinary team. Many patient advocacy groups have contributed with case studies which emphasises the close working relationships with patients.

This handbook covers all areas of nonlocal continuum mechanics including theoretical aspects,computational procedures, and experimental advances. The multidisciplinary scope of articles that comprise this reference are written by internationally recognized experts in the field and stand as the most-up-to-date, established knowledge base on using nonlocal continuum mechanics to characterize material behavior for advanced composites and nano-materials, as well as for engineering scale structures. The handbook is at once a comprehensive reference for academic researchers and engineers in industry concerned with nonlocal continuum mechanics for materials and structures as well as a supplement for graduate courses on a range of topics.

This book gathers the proceedings of the 4th International Conference on Nanotechnologies and Biomedical Engineering, held on September 18-21, 2019, in Chisinau, Republic of Moldova. It continues the tradition of the previous conference proceedings, thus reporting on both fundamental and applied research at the interface between nanotechnologies and biomedical engineering. Topics include: developments in bio-micro/nanotechnologies and devices; biomedical signal processing; biomedical imaging; biomaterials for biomedical applications; biomimetics; bioinformatics and e-health, and advances in a number of related areas. The book offers a timely snapshot of cutting-edge, multidisciplinary research and developments in the field of biomedical and nano-engineering.

This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

This volume focuses on a period in women's lives that is particularly important in the context of preventing major sexual and reproductive diseases. Recommendations by the Italian Society of Pediatric and Adolescent Gynecology, form the basis of this up-to-date and practical book. Experts in the field comprehensively cover all the relevant topics in pediatric and adolescent gynecology, such as pubertal disorders, genital malformations and menstrual cycle disorders. The book will prove a valuable and practice-oriented tool for, gynecologists, pediatricians and endocrinologists, as well as researchers and practitioners interested in the topic.

This atlas presents a practical and systematic approach for performing dermatologic ultrasound. In recent years, the use of this imaging modality for diagnosing pathologic conditions of the skin, hair, nails, scalp, and soft tissues has grown dramatically and there is a demonstrated need for quick access to this information. For common dermatologic entities, richly-illustrated figures and drawings describe the ultrasound normal anatomy, technical guidelines, common findings, variants, key points, and tips and pitfalls. The extensive collection includes clinical and ultrasonographic correlations with 3D color Doppler ultrasound images and high-definition videos produced with state-of-the-art technology and relevant topics such as benign cutaneous and nail tumors and pseudotumors, skin cancer, vascular anomalies, facial ultrasound anatomy for cosmetic purposes, aesthetic complications, inflammatory diseases, etc. The Atlas of Dermatologic Ultrasound is a valuable resourceand a must-have book for radiologists, dermatologists, plastic surgeons, sonographers, residents, and medical professionals who wish to strengthen their knowledge of the wide spectrum of sonographic presentations of dermatologic conditions and successfully integrate this field of ultrasound into their clinical practice.

This book constitutes the thoroughly refereed proceedings of the 8th International Joint Conference on Knowledge Discovery, Knowledge Engineering and Knowledge Management, IC3K 2016, held in Porto, Portugal, in November 2016.The 18 full papers presented were carefully reviewed and selected from 186 submissions. The papers are organized in topical sections on knowledge discovery and information retrieval; knowledge engineering and ontology development; and knowledge management and information sharing.

A state-of-the-art and concise resource presenting the clinical management of pediatric endocrine diseases and disorders, this third edition of the highly regarded textbook covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded third edition includes new topics such as conditions of overgrowth, low bone density and its management, endocrine issues related to sexual identity, mineralocorticoid disorders and endocrine hypertension, and endocrine emergencies. Some existing chapters are expanded to take into account recent advances in the field. Each chapter contains key points, an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risksand benefits of the best therapeutic options available. New to this edition are concluding sections in each chapter containing relevant case material and multiple choice review questions. Pediatric Endocrinology: A Practical Clinical Guide, Third Edition is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.

This new series, based on a bi-annual conference and its topics, represents a major contribution to the emerging science of cancer research and regenerative medicine. Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies. These volumes are invaluable resources not only for already active researchers or clinicians but also for those entering these fields, plus those in industry. Stem Cells: Biology and Engineering is a proceedings volume which reflects papers presented at the Innovations in Regenerative Medicine and Cancer Research conference; taken with its companion volume Tissue Engineering and Regenerative Medicine it provides a complete overview of the papers from that meeting of international experts.

This book will provide the state-of-the-art on most of the topics involved in the ecology and conservation of birds of prey. With chapters authored by the most recognized and prestigious researchers on each of the fields, this book will become an authorized reference volume for raptor biologists and researchers around the world.

Now in a completely revised and expanded third edition, including six new chapters, this user-friendly textbook offers a succinct overview of both the medical and surgical management of reproductive disorders, as well as coverage of associated imaging modalities. Included here are updated chapters on major reproductive endocrinology and infertility issues, such as polycystic ovary syndrome (PCOS), pubertal disorders, amenorrhea, menopause, management of endometriosis and fibroids (including interventional radiology), laboratory and clinical aspects of assisted reproductive technologies (ART), imaging modalities such as ultrasonography and sonohysterography, and hysteroscopic and laparoscopic techniques. New chapters include an expansion of female infertility and fertility, preimplantation diagnosis and screening, osteoporosis, and contraception and sterilization. In addition, each chapter opens with a clinical case presentation and a list of keywords relevant to the topic at hand. Residents, fellows, and new clinicians of obstetrics and gynecology interested in reproductive endocrinology and infertility will find Clinical Reproductive Medicine and Surgery: A Practical Guide a valuable and focused reference.

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases.There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence boththe development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

This book constitutes the thoroughly refereed post-conference proceedings of the 11th International Workshop on Graphics Recognition, GREC 2015, held in Nancy, France, in August 2015. The 10 revised full papers presented were carefully reviewed and selected from 19 initial submissions. They contain both classical and emerging topics of Graphics Recognition, namely symbol spotting; recognition in context; perceptual based approaches and grouping; low level processing; off-line to on-line and interactive systems; structure based approaches; performance evaluation and ground truthing; content based retrieval.

This book constitutes the thoroughly refereed proceedings of the 13th International Conference on Image Analysis and Recognition, ICIAR 2016, held in Póvoa de Varzim, Portugal, in July 2016. The 79 revised full papers and 10 short papers presented were carefully reviewed and selected from 167 submissions. The papers are organized in the following topical sections: Advances in Data Analytics and Pattern Recognition with Applications, Image Enhancement and Restoration, Image Quality Assessment, Image Segmentation, Pattern Analysis and Recognition, Feature Extraction, Detection and Recognition, Matching, Motion and Tracking, 3D Computer Vision, RGB-D Camera Applications, Visual Perception in Robotics, Biometrics, Biomedical Imaging, Brain Imaging, Cardiovascular Image Analysis, Image Analysis in Ophthalmology, Document Analysis, Applications, and Obituaries.The chapter'Morphological Separation of Clustered Nuclei in Histological Images'is published open access under a CCBY 4.0 license at link.springer.com.

This new edition presents information and knowledge on the field of biomedical devices and surgical tools. The authors look at the interactions between nanotechnology, nanomaterials, design, modeling, and tools for surgical and dental applications, as well as how nanostructured surfaces can be created for the purposes of improving cell adhesion between medical devices and the human body. Each original chapter is revised in this second edition and describes developments in coatings for heart valves, stents, hip and knee joints, cardiovascular devices, orthodontic applications, and regenerative materials such as bone substitutes. There are also 8 new chapters that address:Microvascular anastomosesInhaler devices used for pulmonary delivery of medical aerosolsSurface modification of interference screwsBiomechanics of the mandible (a detailed case study)Safety and medical devicesThe synthesis of nanostructured materialDelivery of anticancer molecules using carbon nanotubesNano and micro coatings for medical devicesThis book is appropriate for engineers, material scientists, chemists, physicists, biologists, medical and dental professionals with an interest in biomedical devices and tools, and researchers in the same fields.

Lipids and Skin Health is the first effort to summarize and review the studies, ideas, and research that link lipid metabolism to the largest organ of our body, the skin. The book covers the fundamental biology of the skin, and the major involvement of the transcriptional factors that govern lipid synthesis and the bioactive lipids in this intriguing organ. All layers of skin are presented, as well as their relevant lipids from the epidermis to dermis and even to the hypodermis. The important and unique-to-skin biological pathways are laid out, with a special focus on the various models that demonstrate the essential role of lipid synthesis in skin pathophysiology. The use of lipids in the cosmetic industry is emphasized, and last but not least the involvement of lipids in the clinical setting is also discussed. This book will appeal to healthcare professionals, researchers and dermatology professionals, and will help them to brainstorm new products and opportunities that will target the emerging importance of lipid metabolism in skin for acne, aging, and healthy skin.Apostolos Pappas, Ph.D., is a professional member of the Institute of Food Technology. He started his professional career as a research biochemist in the Skin Research Center of Johnson & Johnson and later served as a group leader at Munich Biotech, where he worked on cancer research. Thereafter he returned to Johnson & Johnson, where he is currently a Research Manager and Fellow focusing on lipid metabolism research. He has authored numerous scientific publications, patent applications, and books.

This comprehensive volume discusses the current scope of umbilical cord blood transplantation (UCBT), including recent controversies and future developments for improving clinical outcomes. Its twenty chapters introduce new applications in regenerative medicine and discuss the latest scientific, regulatory, clinical and investigational aspects of cord blood banking. Physicians from around the world provide a global collaboration which explores strategies for umbilical cord blood expansion, homing, unit selection, and combining of graft sources to improve patient outcomes. Umbilical Cord Blood Banking and Transplantation also reviews advances in pediatric UCBT for hematologic and non-hematologic disorders as well as immune recovery, which is critical to preventing infection. Finally, it compares UCBT with other graft sources in an attempt to understand the optimal graft source for the individual patient. UCBT is an important option for many patients who need a transplant but do not have a family donor or a matched unrelated donor. The collective and timely knowledge presented here is essential reading for any regenerative medicine investigator, cord blood banker, transplant laboratory scientist or clinical physician interested in improving and expanding the applications of umbilical cord blood.