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This book reports on topics at the interface between mechanical and materials engineering, emphasizing aspects related to design, simulation, and manufacturing. It covers advanced methods in design and process engineering applied to mechatronic systems, industrial equipment, turbines, and drives. It covers cutting-edge theoretical and experimental findings relating to material behavior, composites, nanomaterials, and coatings design. Based on the 7th International Conference on Design, Simulation, Manufacturing: The Innovation Exchange (DSMIE-2024), held on June 4–7, 2024, in Pilsen, Czech Republic, this second volume of a 2-volume set provides academics and professionals with extensive information on technologies, trends, challenges, and practice-oriented experience in all the above-mentioned areas.

This book presents the select proceedings of the 3rd International Conference on Mechanical and Energy Technologies (ICMET 2023). It covers a wide range of topics, including robotics and automation, advanced manufacturing technologies, materials science and engineering, thermodynamics, fluid mechanics, automotive engineering, and interdisciplinary areas such as the application of computer science and electronics in mechanical engineering. This is a useful resource for researchers and professionals in mechanical engineering.

The book covers timely topics in mechanical engineering, with a special attention to advances in machine design, product assembly, technological aspects of production, mechatronics and production maintenance. Gathering peer-review contributions to the 8th International Scientific-Technical Conference MANUFACTURING 2024, held on May 14-16, 2024, in Poznan, Poland, it reports on cutting-edge research and methods fostering design processes, optimization of industrial processes, such as welding and molding, and machining, with an emphasis on sustainable solutions. All in all, this book offers a timely guide for researchers and professionals in mechanical engineering and manufacturing, yet it is also intended to foster communication and cooperation between universities and industrial partners.

Von Hippel-Lindau (VHL) disease is an inherited disorder characterized by the abnormal growth of both benign and cancerous tumors and cysts in many parts of the body. Considering the number of manifestations of the VHL disease, screening and management is complex and requires a multidisciplinary effort as well as an understanding of the interplay between all the manifestations. This book is one of the first to provide fundamental knowledge about VHL and the know-how on the various manifestations of this complex syndrome. Various aspects of VHL are reflected in this book's table of contents, written by the leading experts in each field discussed. Comprehensive and easy-to-use, this book offers a detailed and comprehensive analysis of the manifestations and management of patients with VHL and serves as the definitive book on the management of patients with VHL for surgical oncologists, endocrinologists, urologists, neurosurgeons, ophthalmologist, radiologists, and all primary care physicians.

This book includes new results of theoretical and experimental studies of various scales of the processes occurring on the earth including the lithosphere, atmosphere, and hydrosphere. Intensive development of research in these areas is due to several factors: 1) the widespread introduction of computer technology, allowing the calculation of complex phenomena; 2) the invention and improvement of a new generation of geophysical instruments such as remote observation systems based on ships, aircraft, and satellites, providing a large amount of data to objectively reflect a broad picture of the processes; and 3) the development of measurement techniques, creating opportunities for controllable and reproducible laboratory data acquisition for generation of new ideas and concepts. Their recent developments have facilitated our research and understanding of these academic fields. The book enriches the understanding of the geophysical processes taking place in various environments (lithosphere, hydrosphere, and atmosphere), including the anthropogenic one, and it further contributes to their development. This book is a valuable resource for specialists working in the oil, gas, and engineering industry to improve their understandings of the field.

This specialized textbook will be dedicated to the various disease topics of pediatric neurosurgery and management strategies. The text will cover the different aspects of the field of pediatric neurosurgery in a unique way by giving state of the art up-to-date synopsis with references to recent publications. More specifically, the whole book is dedicated to a comprehensive discussion of brainstem tumors and other lesions. It will be composed of 20 chapters. The various chapters will start from updates regarding the development of the nervous system and the clinical differences in assessing the infant or a child in comparison to the adult patient. The book then will focus on various pathologies starting with hydrocephalus, pediatric brain and spine tumors, congenital malformation, spasticity, epilepsy, and more. The proposed textbook will be enriched with diagnostic and surgical images, and illustrations that cover all types of pediatric neurosurgery pathologies, with an emphasis on evidence-based data that reflects the controversies and possible solutions. The main structure of each chapter will include a short synopsis of the topic at hand, questions and answers that will inspire the reader for better understanding, learning objectives, and key references for further reading. Written by experts in the field, Pediatric Neurosurgery Board Review serves as a valuable resource for neurosurgery residents and fellows studying for their neurosurgery exams, as well as an educational material for neurosurgery specialists after graduation by discussing pediatric neurosurgery in more convenient way to review and understand key information in this field.

This book gathers the proceedings of the 16th IFToMM World Congress, which was held in Tokyo, Japan, on November 5–10, 2023. Having been organized every four years since 1965, the Congress represents the world's largest scientific event on mechanism and machine science (MMS). The contributions cover an extremely diverse range of topics, including biomechanical engineering, computational kinematics, design methodologies, dynamics of machinery, multibody dynamics, gearing and transmissions, history of MMS, linkage and mechanical controls, robotics and mechatronics, micro-mechanisms, reliability of machines and mechanisms, rotor dynamics, standardization of terminology, sustainable energy systems, transportation machinery, tribology and vibration. Selected by means of a rigorous international peer-review process, they highlight numerous exciting advances and ideas that will spur novel research directions and foster new multidisciplinary collaborations.

This book offers a timely snapshot of innovative research and developments at the interface between design, manufacturing, materials, mechanical and process engineering, and quality assurance. It covers various manufacturing processes, such as grinding, milling, broaching, and gear machining, including additive manufacturing, vibrational-centrifugal strengthening, laser-ultrasonic surface hardening, and antifriction coatings. It focuses on computer and numerical simulation, mathematical and integrated process modeling, parametric synthesis, virtual prototyping, automatic control, design of manufacturing, mechanical and mechatronics systems. It describes innovative cutting and abrasive processes and combined technologies. It also covers the formation, strengthening, and thermomechanical rolling. It also investigates the temperature field behavior, thermal stability, wear resistance, and other processes of various materials. Gathering the best papers presented at the 5th Grabchenko'sInternational Conference on Advanced Manufacturing Processes (InterPartner-2023), held on September 5–8, 2023, in Odessa, Ukraine, this book provides a comprehensive and up-to-date examination of design, manufacturing, mechanical, materials, and process engineering, as well as quality assurance trends and technologies. Yet, it also aims at fostering international and interdisciplinary communication and collaborations, offering a bridge between the academic and industrial sector.

This book highlights the most important research areas in information and communication technologies, namely the research in fields of modern information technologies that deal with various aspects of the analysis and solution of practically important issues of information systems in general, and contains discussion about the progression from big data to smart data, development of cloud-based architecture, practical implementation of Internet of Things (IoT), the fundamentals of information and analytical activities; studying of modern communication technologies contains original works dealing with many aspects of construction, using research and forecasting of technological and services characteristics of communication systems, as well as research of modern radio electronics technologies that contains actual papers, which show some effective technological solutions that can be used for the implementation of novel radio electronics systems. These results can be used in the implementation of novel systems and to promote information exchange in e-societies. This book offers a valuable resource for scientists, lecturers, specialists working at enterprises, and graduate and undergraduate students who engage with problems in information and communication technologies.

This book contains the first complete translation of the first half of the Pedology of the Adolescent by the Soviet thinker, educator, and teacher L.S. Vygotsky. It was the longest work published in his lifetime and was a correspondence course written by Vygotsky for teachers across the Soviet Union. The book is a sustained argument about the borders of pedology, the nature of the transition between childhood and adulthood, and the concrete character of the distinction between the lower psychological functions that we largely share with animals and those that are specific to fully socialized humans. After an initial methodological introduction, three kinds of maturation—general anatomical, sexual, and sociocultural—are explored. This book will be followed by a companion volume covering pedology of the transitional age as a psychological and social problem.

This book provides a systematic review of the development, function, and patho-physiologic role of plasmacytoid dendritic cells (pDCs) in humans. The chapters of the book discuss the origin and discovery, hematopoietic development as well as molecular regulation of pDCs in the context of immune activation as well as immune tolerance. It also discusses the role of pDCs in human diseases, including infections, autoimmune/inflammatory diseases, cancers and metabolic disorders, and opportunities for pDC‐targeting therapies in these varied clinical contexts.

Diatoms are the most species rich group of algae, and they contribute about 20% of annual global carbon fixation. They play major roles in ocean food webs and global biogeochemical cycles. They are also a target of the biotechnology industry because of their nano-patterned silica cell wall and high lipid content. Diatoms have received increasing attention as more genomes became available and because of the development of genome editing tools such as the CRISPR/Cas9 technology, which has made diatoms as genetically tractable as well-established biological model species. This book provides an overview on diatom molecular biology. It brings together international leading experts in the field to discuss the latest data and developments from genes to ecosystems. As the understanding of diatoms is currently experiencing a step change, it is critical to allow for synergistic approaches on diverse aspects of diatom biology and evolution. The books offers fundamental insights into the molecular life of diatoms; at the same time new scientific concepts are developed based on the application of the latest molecular tools and genomic information to explore the fascinating lifestyle of diatoms.

This book discusses all aspects of pulmonary pathology, including different bacterial, viral, fungal, mycoplasma and protozoan pathogens, accompanied by illustrations that show macro- and histopathological changes. It also presents microbiological, epidemiological and clinical data, with a particular focus on pneumonias of different bacterial aetiologies, influenza, and other viral infections. Further, the book explores the importance of mixed infections, including those in the late stages of HIV infections and virus-bacterial pneumonias, as well as pathological changes in modern tuberculosis, lung granuloma, and respiratory tract inflammation in different age groups.

This proceedings volume provides a fresh perspective on current challenges in cooperation and coopetition in the age of Industry 4.0. Featuring selected papers from the 10th Conference on Management of Organizations'Development (MOD) held in Zamek Gniew, Poland, this volume extends the knowledge of cooperation and coopetition, presents analytic tools used in the research, considers the potential impact of Industry 4.0 on collaboration, and provides recommendations for managerial practice. Interorganizational relations have been a relevant topic in the management sciences in recent years. Globalization, social, cultural, and technological progress are among the factors shaping the environment for collaboration, determining the conditions for development and defining a set of new challenges that managers have to face in today's knowledge-based economy. This book, therefore, explores emerging problems of organizational development in the light of the needs andchallenges of Industry 4.0. Combining the latest theory and practice, the volume provides a realistic outlook on the network economy and interdependencies both within and between sectors.

This book presents the latest trends and challenges in the development of general engineering and mechanical engineering in the agriculture and horticulture sectors.

This book presents the proceedings of the second Vehicle Engineering and Vehicle Industry conference, reflecting the outcomes of theoretical and practical studies and outlining future development trends in a broad field of automotive research. The conference's main themes included design, manufacturing, economic and educational topics.

The second edition of this handbook provides a state-of-the-art overview on the various aspects in the rapidly developing field of robotics. Reaching for the human frontier, robotics is vigorously engaged in the growing challenges of new emerging domains. Interacting, exploring, and working with humans, the new generation of robots will increasingly touch people and their lives. The credible prospect of practical robots among humans is the result of the scientific endeavour of a half a century of robotic developments that established robotics as a modern scientific discipline. The ongoing vibrant expansion and strong growth of the field during the last decade has fueled this second edition of the Springer Handbook of Robotics. The first edition of the handbook soon became a landmark in robotics publishing and won the American Association of Publishers PROSE Award for Excellence in Physical Sciences & Mathematics as well as the organization's Award for Engineering & Technology. The second edition of the handbook, edited by two internationally renowned scientists with the support of an outstanding team of seven part editors and more than 200 authors, continues to be an authoritative reference for robotics researchers, newcomers to the field, and scholars from related disciplines. The contents have been restructured to achieve four main objectives: the enlargement of foundational topics for robotics, the enlightenment of design of various types of robotic systems, the extension of the treatment on robots moving in the environment, and the enrichment of advanced robotics applications. Further to an extensive update, fifteen new chapters have been introduced on emerging topics, and a new generation of authors have joined the handbook's team. A novel addition to the second edition is a comprehensive collection of multimedia references to more than 700 videos, which bring valuable insight into the contents. The videos canbe viewed directly augmented into the text with a smartphone or tablet using a unique and specially designed app. Springer Handbook of Robotics Multimedia Extension Portal: http://handbookofrobotics.org/

This book collates all the current knowledge of cardiac CT and presents it in a clinically relevant and practical textbook format appropriate for both cardiologists and radiologists. The images have been supplied by an experienced set of contributing authors and represent the full spectrum of cardiac CT.The field of Cardiovascular CT has experienced continued rapid evolution due to: 1) advances in technology, 2) expanded spectrum of cardiovascular applications and 3) significant growth in published data including large prospective multicenter studies. As increasing numbers have access to cardiac CT scanners, this book provides all the relevant information on this modality. This is an extensive update of the previous edition bringing the reader up-to-date with the immense amount of updated content in the discipline.

This book discusses the latest advances in people-centered design, operation, and management of broadly defined advanced manufacturing systems and processes. It reports on human factors issues related to various research areas such as intelligent manufacturing technologies, web-based manufacturing services, digital manufacturing worlds, and manufacturing knowledge support systems, as well as other contemporary manufacturing environments. The book covers an extensive range of applications of human factors in the manufacturing industry: from work design, supply chains, evaluation of work systems, and social and organization design, to manufacturing systems, simulation and visualization, automation in manufacturing, and many others. Special emphasis is given to computer aided manufacturing technologies supporting enterprises, both in general and in the manufacturing industry in particular, such as knowledge-based systems, virtual reality, artificial intelligence methods, and manymore. Based on the AHFE 2016 International Conference on Human Aspects of Advanced Manufacturing, held on July 27-31, 2016, in Walt Disney World®, Florida, USA, the book provides readers with a timely snapshot of the enterprises of the future and a set of cutting-edge technologies and methods for building innovative, human-centered, and computer-integrated manufacturing systems.

HNO-Pathologie und Oralpathologie sind die beiden Grundpfeiler einer umfassenden Kopf- und Hals-Pathologie. In der 2. Auflage der HNO-Pathologie sind die vier Hauptregionen der HNO-Heilkunde abgehandelt: Nase und Nasennebenhöhlen, Ohr, Rachen und Tonsillen sowie Larynx. In einer fachübergreifenden Konzeption wird eine enge Verflechtung klinischer und morphologischer Befunde im Hinblick auf die Diagnostik, Prognose und Therapie der HNO-Krankheiten vorgenommen. Die Belange des in der Routinediagnostik stehenden Pathologen werden ebenso wie die Interessen des HNO-Arztes im Hinblick auf die Pathogenese, Prognose und Therapie spezieller HNO-Krankheiten berücksichtigt. Pathologen und HNO-Kliniker mit spezieller Sachkompetenz beteiligen sich an dem Werk.

During its life cycle, a product produces waste that is over 20 times its weight. As such it is critical to develop products that are sustainable. Currently product development processes lack high quality methods and tools that are empirically validated to support development of sustainable products. This book is a compilation of over forty cutting edge international research papers from the 22nd CIRP International Design Conference, written by eminent researchers from 15 countries, on engineering design process, methods and tools, broadly for supporting sustainable product development. A variety of new insights into the product development process, as well as a host of methods and tools that are at the cutting edge of design research are discussed and explained covering a range of diverse topics. The areas covered include:Sustainable design and manufacturing,Design synthesis and creativity,Global product development and product life cycle management,Design for X (safety, reliability, manufacturability, etc.), andDesign taxonomy, ontology and standards. CIRP Design 2012: Sustainable Product Development provides researchers in design, engineering and sustainability access to some of the latest, quality research in this area. Practitioners and educators of engineering design and sustainability will find an empirically validated suite of methods and tools that can be applied and taught to develop their practices.

This book constitutes the refereed proceedings of the International Workshop on Robotics in Smart Manufacturing, WRSM 2013, held in Porto, Portugal, in June 2013. The 20 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers address issues such as robotic machining, off-line robot programming, robot calibration, new robotic hardware and software architectures, advanced robot teaching methods, intelligent warehouses, robot co-workers and application of robots in the textile industry.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

This contributed volume contains the research results presented at the 4th Machining Innovations Conference, Hannover, September 2013. The topic of the conference are new production technologies in aerospace industry and the focus is on energy efficient machine tools as well as sustainable process planning. The target audience primarily comprises researchers and experts in the field but the book may also be beneficial for graduate students.

Bei wenigen Erkrankungen ist in den letzten Dezennien ein so grundlegender Wandel der Anschauungen in bezug auf die Pathologie, die Therapie und schließ­ lich die Prognose eingetreten, wie gerade bei der Syphilis. Dies mag den außer­ ordentlichen Umfang dieses Teiles des Ergänzungswerkes zum Großen Jadassohn­ schen Handbuch erklären, und es ist mir ein aufrichtiges Bedürfnis, schon an dieser Stelle dem Verlag dafür zu danken, daß die Überschreitung der vorgesehenen Druckbogenzahl ohne Widerspruch hingenommen wurde. Um die Größe nicht noch weiter auszudehnen, wurde bewußt darauf verzichtet, auf die Abhandlungen des Originalwerkes in größerem Maße zurückzugreifen, doch glaube ich, daß der Anschluß überall so gefunden wurde, daß die Kontinuität gewahrt blieb. Die Abbildungen des Originalwerkes sind so ausgezeichnet, daß auf weitere Bilder bis auf einzelne Kapitel verzichtet werden konnte. Naturgemäß hat es sich als nötig erwiesen, eine Reihe von Kapiteln neu einzubauen, hingegen andere weg­ zulassen. Es schien zweckmäßiger, die Syphilis des Skeletes, der Muskulatur und der inneren Organe vom pathologischen Anatomen bearbeiten zu lassen. Eine wesentliche Ausweitung mußte naturgemäß die Besprechung der Therapie der Syphilis erfahren, denn hier war es wohl erforderlich, einerseits noch auf die früher geübte Arsenobenzol-Schwermetallbehandlung einschließlich der mit dieser Therapie verbundenen Schäden einzugehen, andererseits aber die moderne Anti­ biotica- und die Glucocorticosteroidmedikation besonders eingehend zu be­ sprechen. Dasselbe ist von der Serodiagnostik zu sagen, welche durch die Ent­ deckung des T. P. I. -Testes die Anschauungen bezüglich Therapieausmaß, Prognose und Heilung zu einem grundlegenden Wandel geführt hat.

Aspects of Lyme Borreliosis is a comprehensive scientific presentation of virtually all aspects of lyme borreliosis. It starts with a concise history of lyme borreliosis and its causative agent, Borrelia burgdorferi. The morphological and biological characteristics of B. burgdorferi are presented, followed by outlines on the ecology and histopathology of LB.The various aspects of the clinical manifestations of LB are systematically dealt with, starting with a clinical overview. A special chapter covers the microbiological diagnosis. After a presentation on the susceptibility of B. burgdorferi in vitro and in animals against a great variety of antibiotics, a thorough discussion on the treatment of LB including criticalremarks follows. The book closes with a chapter on the epidemiology of LB.

Connective tissue diseases demand study because of their frequency, morbidity and mortality. They present intriguing challenges in the fields of diagnosis, management and research. Their range has now expanded enormously so that no individual can master the whole subject, particularly as this relates to their immunological basis. Immunology of Connective Tissue Diseases has been written by experts who are either clinical or basic scientists. The book presents up-to-date reviews of the immunological basis of connective tissue diseases as it impacts on diagnosis, pathogenetic concepts, disease monitoring and management. The book is aimed at physicians interested in understanding the immunological basis of these diseases, and at immunologists who are either entering this field for the first time and would like to have a convenient state-of-the-art account of its status, or who are researching in one area and would like to acquaint themselves with the developments which have taken place in others.

Lanthanides have fascinated scientists for more than two centuries now, and since efficient separation techniques were established roughly 50 years ago, they have increasingly found their way into industrial exploitation and our everyday lives. Numerous applications are based on their unique luminescent properties, which are highlighted in this volume. It presents established knowledge about the photophysical basics, relevant lanthanide probes or materials, and describes instrumentation-related aspects including chemical and physical sensors. The uses of lanthanides in bioanalysis and medicine are outlined, such as assays for in vitro diagnostics and research. All chapters were compiled by renowned scientists with a broad audience in mind, providing both beginners in the field and advanced researchers with comprehensive information on on the given subject.

Collected here are 112 papers concerned with all manner of new directions in manufacturing systems given at the 41st CIRP Conference on Manufacturing Systems. The high-quality material presented in this volume includes reports of work from both scientific and engineering standpoints and several invited and keynote papers addressing the current cutting edge and likely future trends in manufacturing systems. The book's subjects include: (1) new trends in manufacturing systems design: sustainable design, ubiquitous manufacturing, emergent synthesis, service engineering, value creation, cost engineering, human and social aspects of manufacturing, etc.; (2) new applications for manufacturing systems – medical, life-science, optics, NEMS, etc.; (3) intelligent use of advanced methods and new materials – new manufacturing process technologies, high-hardness materials, bio-medical materials, etc.; (4) integration and control for new machines – compound machine tools, rapid prototyping, printing process integration, etc.

Proceedings of the14th European Microscopy Congress, held in Aachen, Germany, 1-5 September 2008. Jointly organised by the European Microscopy Society (EMS), the German Society for Electron Microscopy (DGE) and the local microscopists from RWTH Aachen University and the Research Centre Jülich, the congress brings together scientists from Europe and from all over the world. The scientific programme covers all recent developments in the three major areas of instrumentation and methods, materials science and life science.

The investigations of multiscale problems in multibody system contacts is a most interesting and timely topic which is the subject of intensive research for more than a decade. Many questions have already been answered and the mechanically sound description and simulation is increasingly being applied to practical engineering problems. The IUTAM Symposium on ”Multiscale Problems in Multibody System Contacts” in Stuttgart, Germany which was held February 20-23, 2006 facilitated discussions between researchers active in the?eld and enabled us to review the current state of the subject, and to identify the important topics which require further e?ort. Multiscale problems occur very naturally in contact mechanics. Typically thecontactforcesandstressesareveryhighandthey aretransmittedwithina veryshortperiodoftime.This leadstoquestions,e.g.howtheslowrigidbody motion and the fast motion changes can be considered simultaneously or how interface e?ects couple with wave propagation and the large-scale motion. The purpose of the symposium was to provide a basis for discussion and exchange of new concepts and ideas between scientists from all over Europe and the world. Emphasis was placed also on sharing algorithms and concepts with young researchers who only recently entered the?eld of mechanical c- tacts.

Das Handbuch diagnostische Radiologie stellt in 9 Bänden die modernen radiodiagnostischen Möglichkeiten dar. Die Visualisierung von Organerkrankungen wird von den pathologisch-anatomischen Grundlagen über die klinische Symptomatik bis zur diagnostischen Praxis in synoptischer Betrachtungsweise beschrieben. Die klare Darstellung der Methoden mit Vergleich und Wertung, Einsatzmöglichkeiten und sinnvollen Indikationen unterstützt den Arzt bei der zielgerichteten Diagnosefindung. Alle Inhalte sind praxisgerecht und übersichtlich aufbereitet. Die einheitlich strukturierten Kapitel mit einer Fülle instruktiver Abbildungen sorgen für schnelle Orientierung. Ein Nachschlagewerk, das in der täglichen Routine und bei Problemfällen Hilfe bietet und Lücken zwischen bekannten Monographien über einzelne, sehr spezialisierte Themen schließt.