1. An overview of biochemical technologies for the cancer biomarker miR-21 detection.
- Author
-
Wei B, Huang B, and Zhao X
- Subjects
- Humans, Biomarkers, Tumor genetics, MicroRNAs genetics, Neoplasms diagnosis, Neoplasms genetics
- Abstract
In recent years, the incidence of cancer has continuously increased, in which various miRNAs have been proposed as biomarkers for the early screening of cancer patients. As a consequence, the development of accurate methods for miRNA quantification has become a major research challenge worldwide. As one of the first discovered oncogenic miRNAs, microRNA-21 (miR-21) has been highlighted for its critical role in cancers. This review describes the main techniques currently available for miR-21 detection, compares the differences of the methods and the amplification strategies, and provides an overview of the state of knowledge in the field., (© 2023. The Author(s), under exclusive licence to The Japan Society for Analytical Chemistry.)
- Published
- 2023
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