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This fully-updated third edition of Scleroderma: From Pathogenesis to Comprehensive Managementbuilds upon the well-regarded approach in the previous editions to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. Comprised of the authoritative work of international experts, the new edition includes extensive updated material reflecting major developments in the field. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive and fully up to date resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.

This multidisciplinary textbook has been written and edited by multiple experts in the field to explore and define the management strategies for all types of dialysis access. With kidney failure a major public health problem worldwide and the care of these patients being widely regarded as suboptimal in the conventional surgical and interventional world, this reference combines the experience and knowledge of a world-renowned team of surgeons, interventionalists and nephrologists to definitively address this topic without regard to specialty. Principles of Dialysis Access provides a thorough review of the management of all types of access for patients requiring dialysis. It is designed for access surgeons, interventional radiologists, interventional nephrologists, nephrologists and all others specializing in dialysis access. As the only comprehensive multi-author interdisciplinary textbook on this topic, it is essential reading for all who specialize in this field.

Anesthesia is a practical, clinically based medical science. Its conduct requires Anesthesiologists and Intensivists to learn and understand the principles of applied physics related to equipment responsible for the clinical care of patients. This book is written primarily for anesthetic registrars/residents and their teachers, to assist with preparation for the post graduate, basic science examinations in anesthesia and critical care medicine. Each topic is systematically covered using first principles, contextual examples, and illustrations to explain and demonstrate complex concepts. This comprehensive book is an up-to-date compilation of these scientific principles that can easily be applied to any operating theatre or intensive care unit around the world.

This book focuses on the precise needs of candidates preparing for the viva part of the FRCS, Int-FRCS, and Orthopaedic Board Examinations. With more than 600 candidates annually sitting for these examinations this volume is meticulously crafted to empower aspiring orthopaedists to excel in it.Structured for effortless comprehension, the book is presented in a reader-friendly format that facilitates effective revision. Entirely written by experts who have successfully navigated these examinations its authorship contributes to make it an invaluable resource for aspirant orthopaedists.This practical yet comprehensive book covers high-yield topics essential for passing the exams while also equipping readers with strategies to confidently address even the most unconventional scenarios they may encounter during vivas. This practical resource provides a structured and unparalleled approach to empower aspiring orthopaedists to excel in the FRCS, Int-FRCS, and Orthopaedic Board Examinations.

This book provides a novel method to teach eponymically named physical signs of the alimentary tract and intrabdominal organs. The focus is on the historical aspect of the named signs, how to perform the sign described by the author, and the pathophysiologic mechanisms involved in eliciting a positive test. The goal is to guide the reader to appreciate how these bedside signs provide a more profound understanding of the mechanism of disease. By doing so, they become more than simply rote memorization but an appreciation of how a direct hands-on assessment involving observing, engaging, listening, and touching the patient assists in diagnosis. Hence, these techniques provided the additional benefit of better connecting the practitioner to the patients and maintaining the art of medicine, which is rapidly losing its foothold within the medical community. This book will serve as a teaching tool for learners, teachers, and practicing physicians to preserve the artof the physical examination using a form of a case-based teaching and learning style approach. Illustrations throughout the text provide a visual representation of how to perform the sign. The authors believe this method of teaching and learning is more meaningful to the student in that they will be able to associate the name with the person's historical features, the sign, and its pathophysiologic mechanism(s). Gastrointestinal Eponymic Signs is a must-have resource for medical students, residents, fellows, teaching faculty, and any practicing physician seeking to understand how physical examination signs assist in diagnosis.

This book will provide a concise, focused overview of methods of neurological examination, enabling a focused clinical approach for localization in patients with neurological disorders. Chapters provide a systematic approach for clinical examination along with essential aspects of the neuro-anatomy to provide specific information about disease localization. This book assists medical students pursuing DM/DNB- Neurology, MCH -Neurosurgery, MD/DNB- Internal medicine, MBBS students, and Clinicians, including Neurologists, Neurosurgeons, Internal medicine physicians, and other neuro-scientists. It provides a unique opportunity to formulate correct concepts for clinical neurological examination and hence localization but also provides the opportunity to quickly revise the entire book in a short time.

This book primarily aims to assists doctors from non-neuroscience background to acquire knowledge about common neurological disorders encountered in a resource-constrained setup in a case-based and practical approach. The book elucidates the value of proper and systematic approach to the patient, how proper history taking and clinical evaluation, followed by appropriate investigations can narrow down the differential diagnoses and help proper and timely management of the patients.The book covers most of the common neurological disorders and scenarios encountered in clinical practice and will benefit clinicians facing difficult cases, particularly those involving fundamental research and diagnostic methods. This book is useful for physicians working in internal medicine, physicians handling neurology cases in resource-constrained facilities, and fellows in neurology. The contents of this book support and practically enhance the knowledge acquiredfrom other text books.

This extensively updated edition provides a comprehensive review of intensive care for neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period in two comprehensive volumes. The Editors of this second volume present a comprehensive textbook that incorporates best practice/evidence-based medicine and performance improvement, while it champions the three characteristics needed in our neuro–ICUs: patient and family centered high-quality care, education, and discovery. This volume concentrates on perioperative management, monitoring and pharmacotherapy, examining the neurological problems most frequently seen in intensive care, and describes the various types of neurosurgery and critical features of the management of patients. General issues are discussed across the textbook, such as cardiac care, fluids and electrolytes, nutrition, and monitoring as well as more specific conditions and complications including elevated intracranial pressure, seizures, and altered mental states. Listening to an injured brain is not easy. It takes knowledge, dedication, and understanding of the critically ill patient and their family. Textbook of Neurointensive Care Volume 2: Perioperative Management, Monitoring, Pharmacotherapy provides the reader with a detailed resource for studying this most complex area of medicine. It is thus essential reading for all trainees and professionals in critical care, neurosurgery, anesthesia and neurology.

Medical imaging is fundamental to modern healthcare, and its widespread use has resulted in creation of image databases. These repositories contain images from a diverse range of modalities, multidimensional as well as co-aligned multimodality images. These image collections offer opportunity for evidence-based diagnosis, teaching, and research. Advances in medical image analysis over last two decades shows there are now many algorithms and ideas available that allow to address medical image analysis tasks in commercial solutions with sufficient performance in terms of accuracy, reliability and speed. Content-based image retrieval (CBIR) is an image search technique that complements the conventional text-based retrieval of images by using visual features, such as color, texture, and shape, as search criteria. This book emphasizes the design of wavelet filter-banks as efficient and effective feature descriptors for medical image retrieval.Firstly, a generalized novel design of a family of multiplier-free orthogonal wavelet filter-banks is presented. In this, the dyadic filter coefficients are obtained based on double-shifting orthogonality property with allowable deviation from original filter coefficients. Next, a low complex symmetric Daub-4 orthogonal wavelet filter-bank is presented. This is achieved by slightly altering the perfect reconstruction condition to make designed filter-bank symmetric and to obtain dyadic filter coefficients. In third contribution, the first dyadic Gabor wavelet filter-bank is presented based on slight alteration in orientation parameter without disturbing remaining Gabor wavelet parameters. In addition, a novel feature descriptor based on the design of adaptive Gabor wavelet filter-bank is presented. The use of Maximum likelihood estimation is suggested to measure the similarity between the feature vectors of heterogeneous medical images. The performance of the suggested methods is evaluated on three different publicly available databases namely NEMA, OASIS and EXACT09. The performance in terms of average retrieval precision, average retrieval recall and computational time are compared with well-known existing methods.

This textbook explores the fundamental qualitative and quantitative aspects of veterinary physiology. It presents the morphological description of the organs, tissues, and cells involved in the physiological system with species variation. The book provide the most up-to-date information and in depth knowledge in animal physiology. The book addresses a broad range of topics, including the physiology of digestion in, monogastric animals, ruminants, and birds, and cardio vascular and respiratory system in different animals. The chapters contain a wealth of information on the areas related to the endocrine system, excretory system, body fluid homeostasis, hematology, male and female reproductive systems, coordination of body functions, and regulation of brain functions and sense organs. Further, this book acquaints students with advanced topics like immune system, assisted reproductive technology, ovarian dynamics, environmental physiology and thermoregulation, and behavioral physiology. This textbook contains clear illustrations including graphical abstracts and study questions for each chaptermaking this book a valuable learning resource for veterinary sciences and veterinary medicine students.Further to attract students and create interest in them, interesting facts related to animal physiology have also been highlighted in form of “Know more widges”.​

The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics.This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used toassess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.

This book offers a complete focus on the radiographic analysis of the abdominal wall and hernias. An estimated 20 million hernias are repaired annually throughout the world. As the technology utilized to complete hernia repairs becomes more complex, surgeons are required to have a more thorough understanding of the radiographic anatomy and diagnostic modalities used to evaluate hernias. Furthermore, the amount that now goes into the preoperative planning of hernias for complex repairs (such robotic and open transversus abdominis muscle release procedures) requires an understanding of radiology and the ability to identify nuances of anatomy offered by the imaging. The use of mesh and extent of re-do hernia repairs has also complicated radiographic evaluation of hernias. The text is a comprehensive review of abdominal wall imaging broken down into individual types of hernia. Each hernia type is discussed with consideration to the best type of imaging evaluation, unique radiographic findings and considerations prior to repair. Representative images, diagrams and videos are used to point out anatomy and features of the hernia. This text offers the first-of-its-kind standardized approach to evaluating hernias radiographically. Most importantly, each hernia and chapter is approached with the surgeon in mind, meaning, authors explain the radiology based on anatomy and with a plan for surgical repair on the horizon. Select chapters include illuminating videos to give context to the text. This is an ideal guide for practicing surgeons and trainees treating patients with hernias.

Few books have been published to assist local and visiting clinicians in addressing opportunities to expand surgical care in low- and middle-income countries. With contributions from international experts and surgical leaders, this book serves as a valuable resource for local and visiting faculty, trainees, and students in their endeavors to deliver surgical services in existing facilities as well as to develop new infrastructures for specialized surgical care. This book presents an anthology of important lessons gleaned from the experiences of participants in selected academic global surgery centers and existing partnerships all over the world. Contributing authors summarize methods to build partnerships and expand capacity with a focus not only on how to, but also on what worked, what didn't work, and what could be done differently. They discuss specific examples ranging from implementing colon cancer screening to building a transplant program. In addition, several chapters describe approaches to diagnosis and management of specific surgical pathologies in limited resource environments as a complement to standard surgical texts in general surgery, thoracic surgery, neurosurgery, urology, obstetrics and gynecology, orthopedics, and surgery for contractures and burns. Practical and user-friendly, Global Surgery encapsulates the increasing enthusiasm of young faculty, trainees and medical students to improve access to surgical care in the world's low- and middle-income countries.

This third edition offers comprehensive, up-to-date coverage of all areas of interventional pulmonology, a minimally invasive endoscopic method for diagnosing and treating lung disorders. The text is divided into nine sections on the major areas of interventional pulmonology, including basic bronchoscopy, lung cancer staging, tracheobronchial obstructions, endobronchial treatments for asthma and emphysema, as well as a new section on interventional procedures during the COVID-19 pandemic. Chapters explore specific procedures and techniques, including medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, and electromagnetical navigation with coverage of history, indications and contraindications, up-to-date, evidence-based reviews, and recommendations. The COVID-19 pandemic has also changed medicine in many permanent ways, and that will be considered closely for every intervention. Additionally, there are new chapters on interventions in pediatric patients and artificial intelligence bronchoscopy, two topics that are not frequently covered. This inclusive volume concludes with a look towards both the past and future of interventional pulmonology with experimental techniques currently being tested. This volume is a must have for pulmonologists, interventional radiologists, thoracic surgeons, pulmonary oncologists, ENT physicians, anesthesiologists, intensive care specialists, and their teams.

Asthma is a common chronic respiratory disease that causes substantial morbidity and has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To update the field on the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan R Brasier and Nizar N Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.

This book provides a concise overview of neonatal imaging. After a short clinical introduction on the crucial role of imaging in diagnosing and treating neonatal conditions, it discusses the various methods (ultrasound, digital radiography, fluoroscopy, CT, and MRI) available and explains in detail how they have to be adapted for neonatal applications. Chapters feature imaging findings and differential diagnoses for the most common neonatal conditions. Additionally, some relevant aspects of foetal imaging are presented. Written by an interdisciplinary team, Imaging in Neonates is a practical resource for daily use in the ward for all medical professionals involved in treating neonates.

The aim of this book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, is to educate and train practitioners in the safe and competent use of diagnostic ultrasound imaging in the visualization and interpretation of different conditions. Specifically, the program will train practitioners in the safe and accurate acquisition of ultrasound images in the examination and monitoring of patients in intensive care settings. The readers will be able to obtain knowledge on the use of ultrasound in a safe and effective manner and to learn how ultrasound examination can be used to optimize clinical management of patients. The chapters include ultrasound physics, ultrasound examination technique, optimization of the image, bedside ultrasound diagnosis of different diseases. Different domains will be addressed from the evaluation of different organs such as the heart, the lung, the abdomen, vessels and brain, focusing on the basic skills required to an intensivists working in the general Intensive Care Unit settings. The book - richly illustrated and with electronic supplementary contributions - is intended for anaesthetists and intensivists with basic knowledge of ultrasound physics and practical experience of ultrasound.

This book covers all aspects of Percutaneous Renal stone surgeries, starting with a step-by-step approach to patient evaluation and pre-operative preparation to the actual planning of surgeries. The topics covered give a general outline of stone treatment as well as the handling of different situations. It covers new developments in the field with a new approach to the treatment of Stone disease. The special chapters of interest are training in such surgeries and troubleshooting, emphasizing the management of difficulties such as residual stones and complications faced during surgeries. An essential aspect of this book is a detailed chapter on the intricacies and their management, which serves as a helpful tool to novice surgeons, who can be well prepared in advance to avoid possible complications. The book serves as a primer for the practical training of young surgeons and trainees as well. It will help them widen their horizons on all the aspects of stone surgery before embarking on this journey and will help to inspire many budding surgeons to take up and specialize in this surgery. Surgeons, at the mid-career level, will also be able to refresh their knowledge, learn about the newer technologies and the latest technological advancements in this field covered in this book. For surgeons and academicians at all stages of their careers, this comprehensive book, covering all aspects of the popular technique of PCNL, is helpful to update their knowledge of this subject.

General surgery is the common ancestor of all surgical specialties. Within general surgery, many subspecialty areas of practice have evolved. This book is the first manual recognizing the growing role General Surgeons play in Head & Neck Surgery. From benign to malignant conditions and form ablative to reconstructive challenges, the renowned comprehensive capability of the General Surgeon is well suited to demands of this discipline. Each chapter details relevant anatomical considerations to enable understanding of this complex regional specialty and the full range of head and neck pathologies with requisite assessment, investigation, surgical and relevant reconstructive techniques. Written by a multidisciplinary, international team of recognized experts, this textbook is a practical but comprehensive guide for both candidates preparing for final surgery examinations as well as general surgeons requiring an up-to-date source of definitive advice on topics of this regional specialty.

The Video-Atlas of Pulmonary Sublobar Resections aims to be a reference multimedia book for Thoracic Surgeons. Mainly focused on operative technical aspects, each individual segmentectomy and many combinations are described. Each chapter opens with anatomical 3D reconstructions of the segment and its bronchoscopic anatomy. Then, the main steps for performing the procedure, that are illustrated in high-definition (HD) video-clips and figures, are described. Expert authors highlight specifical tips & tricks for succesfully performing the resection, and include anatomical variations that also illustrate with HD video-clips.This illustrated guide provides thoracic surgeons with an incredibly useful tool for learning and improving their technique in sublobar resections.Videos and more: Download the free Springer Multimedia App - Scan dedicated images in this book to stream videos or access and download supplementary material.

The second edition comprehensively reviews the wide field of rare pulmonary diseases. Issues such as less common diseases affecting the airways, systematic disorders with lung involvement, interstitial lung diseases, and many other orphan conditions of the lungs are explored in this book. The progress and advances made in the field and the limited number of patients presenting each condition makes it very difficult for clinicians to be up-to-date in this field. Readers will discover how to diagnose and manage these rare orphan diseases. Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease is a practical, informative book written by a team of international authors with much experience in rare pulmonary diseases Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease, second edition provides synthesized and easily accessible information about the main orphan lung diseases, to aid clinicians in charge of patients with rare disease,or who consider the diagnosis of a rare disease in their patient. It is a practical, informative guide written by a team of international experienced authors in rare pulmonary diseases.

Birds have and continue to fascinate scientists and the general public. While the avian respiratory system has unremittingly been investigated for nearly five centuries, important aspects on its biology remain cryptic and controversial. In this book, resolving some of the contentious issues, developmental-, structural- and functional aspects of the avian lung-air sac system are particularized: it endeavors to answer following fundamental questions on the biology of birds: how, when and why did birds become what they are? Flight is a unique form of locomotion. It considerably shaped the form and the essence of birds as animals. An exceptionally efficient respiratory system capacitated birds to procure the exceptionally large quantities of oxygen needed for powered (active) flight. Among the extant air-breathing vertebrates, comprising ~11,000 species, birds are the most species-rich-, numerically abundant- and extensively distributed animal taxon. After realizing volancy,they easily overcame geographical obstacles and extensively dispersed into various ecological niches where they underwent remarkable adaptive radiation. While the external morphology of birds is inconceivably uniform for such a considerably speciose taxon, contingent on among other attributes, lifestyle, habitat and phylogenetic level of development have foremost determined the novelties that are displayed by diverse species of birds.Here, critical synthesizes of the most recent findings with the historical ones, evolution and behavior and development, structure and function of the exceptionally elaborate respiratory system of birds are detailed. The prominence of modern birds as a taxon in the Animal Kingdom is underscored. The book should appeal to researchers who are interested in evolutionary processes and how adaptive specializations correlate with biological physiognomies and exigencies, comparative biologists who focus on how various animals have solved respiratory pressures, people who study respiration in birds and other animals and ornithologists who love and enjoy birds for what they are – profoundly interesting animals.

People live in indoor environment about 90% of lifetime and an adult inhales about 15 kg air each day, over 75% of the human body's daily mass intake (air, food, water). Therefore, indoor air quality (IAQ) is very important to human health. This book provides the basic knowledge of IAQ and highlights the research achievements in the past two decades. It covers the following 12 sections: introduction, indoor air chemicals, indoor air particles, measurement and evaluation, source/sink characteristics, indoor chemistry, human exposure to indoor pollutants, health effects and health risk assessment, IAQ and cognitive performance, standards and guidelines, IAQ control, and air quality in various indoor environments. It provides a combination of an introduction to various aspects on IAQ studies, the current state-of-knowledge, various advances and the perspective of IAQ studies. It will be very helpful for the researchers and technicians in the IAQ and the related fields. It is also useful for experts in other fields and general readers who want to obtain a basic understanding of and research advances in the field of IAQ.A group of experts in IAQ research have been recruited to write the chapters. Their research interests and experience cover the scope of the book. In addition, some experienced experts in IAQ field have been invited as advisors or reviewers to give their comments, suggestions and revisions on the handbook framework and the chapter details. Their contribution guarantees the quality of the book. We are very grateful to them. Last but not least, we express our heartfelt thanks to Prof. Spengler, Harvard University, for writing the foreword of the current Handbook of Indoor Air Quality both as a pioneer scientist who contributed greatly to indoor air science and as an Editor-in-chief of Handbook of Indoor Air Quality 2001, 1st ed. New York: McGraw-Hill. In addition to hard copies, the book is also published online and will be updated by the authors as needed to keep it aligned with current knowledge. These salient features can make the handbook fresh with the research development.

This comprehensive book addresses the acute emergencies in neuromuscular disease from a novel perspective, focusing on clinical management and treatment of these disorders rather than the more traditional neuropathology, neurogenetics, and neurophysiology approaches. The book fills the gap in guidelines by providing an evidence-based guidance for the clinical adult or pediatric neurologist confronted by an acutely ill patient in a potentially life-threatening situation. The book is structured according to pathophysiological principles, but each chapter is strictly organised around case vignettes that emphasize clinical relevance allowing the non-specialist to access complex scientific backgrounds. The electronic supplementary material and multimedia are provided as an integral tool to facilitate accessibility and understanding of a notoriously difficult field of neurology. Finally, the role of patients, who are increasingly involved in many management decisions, is highlighted in a chapter on ethical issues discussing withholding or withdrawing life-sustaining therapy, patient end-of-life values, wishes and preferences, and on advanced directives. The publication is aimed equally at the non-specialist neurologist in frontline clinical practice confronted by a rare disorder needing immediate management decisions, at the clinical specialist referring for guidance in specific management aspects, and at the specialist researcher keen to maintain clinic relevance.

The eight-volume set LNCS 13431, 13432, 13433, 13434, 13435, 13436, 13437, and 13438 constitutes the refereed proceedings of the 25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022, which was held in Singapore in September 2022.The 574 revised full papers presented were carefully reviewed and selected from 1831 submissions in a double-blind review process. The papers are organized in the following topical sections:Part I: Brain development and atlases; DWI and tractography; functional brain networks; neuroimaging; heart and lung imaging; dermatology;Part II: Computational (integrative) pathology; computational anatomy and physiology; ophthalmology; fetal imaging;Part III: Breast imaging; colonoscopy; computer aided diagnosis;Part IV: Microscopic image analysis; positron emission tomography; ultrasound imaging; video data analysis; image segmentation I;Part V: Image segmentation II; integration of imaging with non-imaging biomarkers;Part VI: Image registration; image reconstruction;Part VII: Image-Guided interventions and surgery; outcome and disease prediction; surgical data science; surgical planning and simulation; machine learning – domain adaptation and generalization;Part VIII: Machine learning – weakly-supervised learning; machine learning – model interpretation; machine learning – uncertainty; machine learning theory and methodologies.

The book offers a comprehensive overview of ENT diseases during pregnancy, postpartum and lactating period. It brings together the experience of authors from more than 25 countries and aims to provide a broader understanding of the diagnosis, prevention and treatment of the ENT pathologies in pregnant and lactating women. The book is organized in 7 main parts according to the ENT subspecialties, and each chapter features a reader-friendly, uniform structure. It includes developments about COVID-19 infection. ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation will appeal to a wide readership, from ENT practitioners through allergists and pulmonologists, to trainees and students in ENT, obstetrics/gynecology.​

This textbook is a fully updated and revised third edition of a highly successful practical guide to the care of the polytrauma patient. Broadening its readership to students, this new edition comprehensively describes the clinical course of multiple and severe injuries, from the accident scene to rehabilitation.It provides essential practical information on the care of patients both with blunt and penetrating trauma to multiple body regions, and discusses the management of truncal injuries (head, chest, abdomen) as well as fractures of the extremities, pelvis and spine. Further, the book highlights associated injuries that may alter decisions concerning patients with polytrauma. This new, revised edition takes full account of recent developments, including the increasing economic pressure on health care systems, prehospital treatment, changes in trauma systems and related education, and the improved survival of polytrauma patients. Also covering improved monitoring optionsalong with issues in late patient outcomes and rehabilitation this work will greatly assist students, emergency personnel, trauma surgeons, orthopaedic traumatologists, and anesthesiologists.

This unique clinical guide will explore specific evidence-based literature supporting physical therapist guided exercises and interventional treatments for commonly prevalent orthopedic spine and extremity presentations. Using this book, the sports medicine and interventional pain physician will be better able to coordinate therapy exercises after interventional treatments with their physical therapy colleagues. This will include a treatment course that will monitor progress in restoring and accelerating patients'function. A myriad of musculoskeletal conditions affecting the spine, joints and extremities will be presented, including tendinopathies, bursopathies, arthritis, fractures and dislocations - everything a clinician can expect to see in a thriving practice. Each chapter, co-authored by a physician and a physical therapist, will follow a consistent format for ease of accessibility and reference – introduction to the topic; diagnosis; medical, interventional, and surgical management – and will be accompanied by relevant radiographis, figures and illustrations. Additional topics include osteoarthritis, rheumatic disorders, entrapment syndromes, the use of orthobiologics, and more. Comprehensive enough to function as a learning tool, but practical and user-friendly enough for quick reference, Clinical Guide to Musculoskeletal Medicine will be an essential resource for sports medicine physicians, interventional and physical therapists.

There has been significant progress in the field of spinal disorders in very young children over the past two decades. However, the treatment of such conditions remains challenging due to the age of the patient, different etiologies, associated morbidities and the progressive nature of the deformity. Depending on the etiology of the deformity, these children are often cared for by multiple specialists including pediatricians, pulmonologists, pediatric orthopedists or orthopedic spine surgeons, pediatric surgeons, pediatric neurosurgeons, neurologists and oncologists. Health professionals in all of the mentioned disciplines are involved in the management of these patients, which is why compiling a comprehensive text that is not limited to orthopedic specialists is essential. Since the second edition of this book was published, there has been a significant body of literature that has been published and advances made in the care of young children with spinal and thoracic deformities. This new edition will effectively help to standardize the care of these patients. Furthermore, other professionals, such as nurses, physical therapists and healthcare professionals in training, are usually not familiar with these conditions and are in need of a reference book to consult when caring for young children with spinal deformities. Sections are arranged thematically and comprise a comprehensive presentation of the current knowledge on disorders of the growing spine. After opening sections discussing general considerations and patient evaluation and diagnosis, subsequent sections describe the various categories of spinal deformity - idiopathic, congenital, neuromuscular, syndromic, and others - followed by surgical and non-surgical management strategies, both traditional and growth-friendly. Concluding sections address patient care and outcomes and outline future directions for research and practice.

The fully updated fifth edition of this highly successful textbook provides an integrated symptom- and issue-based approach to internal medicine with easily accessible, high-yield clinical information. For each topic, carefully organized sections on different diagnoses, investigations, and treatments are designed to facilitate patient care and examination preparation. Numerous clinical pearls and comparison tables are provided to help enhance learning, and international units (US and metric) are used to facilitate application in everyday clinical practice. In addition to the central tenets of internal medicine, the book covers many highly important, rarely discussed topics in medicine, including: palliative care, obstetrical medicine, transfusion reactions, needle stick injuries, interpretation of gram stain, depression and code status discussion. This fifth edition additionally includes new coverage of the coronavirus-19 and cancer survivorship while being fully updated throughout. Authors present this information in a streamlined fashion, preserving the book's pocket-sized, quick reference format. Approach to Internal Medicine continues to serve as an essential reference primarily for medical students, residents, and fellows -- with practicing physicians, nurses, and advanced practice providers also finding the text of value as a point of care reference.

This book provides an extensive overview of the role of imaging in the detection, diagnosis, management, and follow-up of tuberculosis. Chapters cover the disease's epidemiology and pathophysiology, microbiological diagnosis and pathology relevant to radiologists, and the distinct aspects of imaging tuberculosis at various locations and body systems. This book discusses recent advances in imaging pertaining to tuberculosis, and addresses the approach to patients with tuberculosis and HIV co-infection. The final chapter offers an algorithmic approach to the diagnosis and management steps of tuberculosis. Imaging of Tuberculosis is an updated and comprehensive reference source that covers imaging of tuberculosis in a structured fashion and is valuable for radiologists.

This is the world's first reference book covering the role of Yoga in Cardiovascular Diseases. It details epidemiology, physiology, pathology, prevention, and management of cardiovascular diseases based on the current scientific understanding of Yoga. Seventy-five experts from four continents, including the most notable names, contributed to this work to create the world's first comprehensive reference literature on Yoga in cardiovascular medicine. The chapters cover information related to Yoga, both as prevention and therapy, including coronary artery disease, heart failure, and arrhythmias. In addition, important cardiovascular topics like obesity and diabetes mellitus are also included. A special chapter covers the role of Yoga in the prevention of cardiovascular complications in COVID-19 patients.

This is the first book to present a carefully chosen and annotated selection of the unpublished writings and correspondence of the English logician John Venn (1834-1923). Today remembered mainly as the inventor of the famous diagram that bears his name, Venn was an important figure of nineteenth-century Cambridge, where he worked alongside leading thinkers, such as Henry Sidgwick and Alfred Marshall, on the development of the Moral Sciences Tripos. Venn published three influential textbooks on logic, contributed some dozen articles to the then newly-established journal Mind, of which he became co-editor in 1892, and counted F.W. Maitland, William Cunningham and Arthur Balfour among his pupils. After his active career as a logician, which ended around the turn of the 20th century, Venn reinvented himself as a biographer of his University, College and family. Together with his son, he worked on the massive Alumni Cantabrigienses, which is still usedtoday as a standard reference source. The material presented here, including the 100-page Annals: Autobiographical Sketch, provides much new information on Venn's philosophical development and Cambridge in the 1850s-60s. It also brings to light Venn's relation with famous colleagues and friends, such as Leslie Stephen, Francis Galton, and William Stanley Jevons, thereby placing him at the heart of Victorian intellectual life.

The book is a question-and-answer guide to interventional radiology. This pocket resource addresses both general IR and subspecialty topics, providing accurate, on-the-spot answers. Students can read the text from cover to cover to gain a general foundation of knowledge that can be built upon when they begin their rotation or use specific chapters to review a subspecialty before starting a new rotation or joining a new service. The book begins with a general introduction to IR and its common procedures and tools, and is then organized by subspecialties (like vascular disease, oncology, and genitourinary), focusing on common conditions. The book's two-column format provides questions on the left and answers on the right to facilitate rapid-fire review that includes many classic images to facilitate pattern recognition skills. This book is an ideal, on-the-spot reference for medical students, residents, and practicing interventional radiologists seeking fast facts on diagnosis and treatment with interventional radiology.

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as diabetes and obesity. As the cases and death rate remain high, there are justified fears of this virus remaining for several months or years to come. To address this, a rapid and unprecedented worldwide mobilization effort has begun to identify effective treatments and develop vaccines. As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers'understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss new treatment approaches, vaccine development, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.

This book provides an overview of the latest experimental work on sex-based differences in lung function and inflammation. Readers will learn how these differences relate to individual predispositions for the development of lung disease in men and women, and in different stages of their reproductive lives. Further, the book focuses on diseases that predominantly affect women or men, with an emphasis on the physiological mechanisms underlying their pathobiology. In turn, these findings are complemented by chapters on recent studies, which investigate how circulating sex hormone levels impact the lung's innate immune response to environmental agents and air pollution. The pathogeneses of asthma and viral respiratory infection are also major focus areas. As an outlook, the book also discusses current and future research directions aimed at developing sex-specific therapies for lung disease. To examine these anatomical and physiological differences in the male and female respiratory systems, the authors employ a broad range of methods from molecular and clinical biology. Accordingly, the book will be a fascinating read for physiologists and clinicians alike.

This extensively revised edition is an essential reference for physicians involved in the diagnosis, referral and treatment of the thoracic outlet syndrome (TOS). TOS is made up of a constellation of problems resulting from pathology at the thoracic outlet in the neck. Busy specialty practice sees multiple affected patients in every clinic, but TOS can often be difficult to diagnosis. Thoracic Outlet Syndrome explores all possible ancillary care issues surrounding this complex condition, including rehabilitation, disability, natural history and medicolegal issues, and aims to stimulate research, discussion and a sense of community between professionals involved in this area. Vascular and thoracic surgeons, neurosurgeons, neurologists, psychiatrists and psychologists, physical therapists, occupational medicine specialists and pain specialists will find this book a must read for successful treatment, referral and diagnosis of TOS in clinical practice.

This book covers the up-to-date advancement of respiratory monitoring in ventilation support as well as detecting the physiological responses to therapeutic interventions to avoid complications. Mechanical ventilation nowadays remains the cornerstone in life saving in critically ill patients with and without respiratory failure. However, conclusive evidences show that mechanical ventilation can also cause lung damage, specifically, in terms of ventilator-induced lung injury.Respiratory monitoring encloses a series of physiological and pathophysiological measurements, from basic gas exchange and ventilator wave forms to more sophisticated diaphragm function and lung volume assessments. The progress of respiratory monitoring has always been accompanied by advances in technology. However, how to properly conduct the procedures and correctly interpret the data requires clear definition.The book introduces respiratory monitoring techniques and data analysis, including gas exchange, respiratory mechanics, thoracic imaging, lung volume measurement, and extra-vascular lung water measurement in the initial part. How to interpret the acquired and derived parameters and to illustrate their clinical applications is presented thoroughly. In the following part, the applications of respiratory monitoring in specific diseases and conditions is introduced, including acute respiratory distress syndrome, obstructive pulmonary diseases, patient-ventilator asynchrony, non-invasive ventilation, brain injury with increased intracranial pressure, ventilator-induced diaphragm dysfunction, and weaning from mechanical ventilation.This book is intended primarily for ICU physicians and other practitioners including respiratory therapists, ICU nurses and trainees who come into contact with patients under mechanical ventilation. This book also provides guidance for clinical researchers who take part in respiratory and mechanical ventilation researches.

This book constitutes the proceedings of the 27th International Conference on Information Processing in Medical Imaging, IPMI 2021, which was held online during June 28-30, 2021. The conference was originally planned to take place in Bornholm, Denmark, but changed to a virtual format due to the COVID-19 pandemic.The 59 full papers presented in this volume were carefully reviewed and selected from 200 submissions. They were organized in topical sections as follows: registration; causal models and interpretability; generative modelling; shape; brain connectivity; representation learning; segmentation; sequential modelling; learning with few or low quality labels; uncertainty quantification and generative modelling; and deep learning.

This book covers all aspects of PET-CT including newer applications involving infection and inflammation and basic information on PET-CT new tracers. It explains the approach, protocols and miscellaneous applications about various infections and inflammation that helps in its early and better diagnosis in multiorgan and multisystem involvements in routine clinical practice.Chapters provide systematic approach to the diagnosis of various infections such as bacterial, viral, tuberculosis, inflammatory pathologies and overlap in coexisting tumors and superadded/associated infections. This book offers assistance to medical practitioners in understanding various advantages of PET-CT in single scan as compared to different modalities for diagnosis as well as oncologists dealing with concurrent malignant and non-malignant conditions, students, and interns.

This book offers a comprehensive overview of the basic physiology of the cardiac and pulmonary systems, tools for cardiopulmonary monitoring, and related issues in the management of specific conditions. The volume is divided into three main parts. The first part examines the functional basis of normal and abnormal physiology, organized into cardiac and pulmonary units and followed by a “combined” interactive component. The next section discusses cardiopulmonary monitoring tools and variables and is also divided into cardiac (e.g, echocardiography, heart rate, cardiac output), pulmonary (e.g, lung volume, pleural pressure, electrical impedance tomography), and combined tools such as radiology/MRI and tissue perfusion tests. The third section concerns the management and application of specific clinical problems such as pulmonary hypertension, cardiac shunts, cardiogenic shock, and ECMO with an emphasis on the physiological basics. Cardiopulmonary Monitoring: Basic Physiology, Tools, and Bedside Management for the Critically Ill is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, critical care, emergency medicine, anesthesiology, and radiology.

This book proposes a novel learning approach that complements and augments the prevailing method of case-based learning. Learning these signs requires the application and integration of the fundamental skills of observation, palpation, percussion, and auscultation, and in more advanced cases, the use of maneuvers performed at the patient's bedside. The book provides a discussion of the utility of the signs and reviews the mechanism and pathophysiology of related cardiovascular diseases. Each chapter discusses eponymic signs for a variety of cardiovascular diseases such as atherosclerosis, heart failure, hypertension, venothromboembolism, ischemic heart disease, pericarditis, and peripheral vascular disease. Finding a particular sign during the physical examination enhances clinical suspicion for a specific cardiovascular disease, directing physicians to obtain more specific studies to confirm a diagnosis. This should lead to the delivery of more efficient care with the potential benefit of lowering health care costs. Cardiovascular Eponymic Signs: Diagnostic Skills Applied During the Physical Examination is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, primary care, and internal medicine.

This book uses a case-based approach to provide current information on a range of medical issues with the goal of enhancing preoperative evaluation and optimization. It meets the market need for a resource that concisely encapsulates current knowledge on the medical management of specific topics in a setting relevant to the preoperative clinic. In so doing the book aims to improve patient care and safety, enhance resource use, facilitate appropriate and timely management of preexisting conditions and diminish patient concerns.Organized into sections according to body system, each section consists of chapters delineating a specific disorder. Each chapter starts with a clinical vignette followed by a question-and-answer style investigation of the relevant issues. These questions attempt to address commonly encountered clinical dilemmas where opinion often differs between, and occasionally within, medical sub-specialties. Expertly written chapters are also supplemented bya number of chapters which address special considerations such as the frail patient and chronic opioid use.Preoperative Assessment: A Case-Based Approach is an invaluable reference for all physicians involved in preoperative assessment including anesthesiologists, surgeons, internists, family doctors and residents in these fields. Nurse practitioners and other allied heath professionals involved in preoperative evaluation may also find this a book a valuable and timely resource.

This book provides a practical guide for managing a variety of problems encountered by the clinician in managing patients with systemic sclerosis. Chapters take a problem-orientated approach to help the reader cut through potential barriers that can arise when working with different medical specialities. Management strategies for a broad range of conditions, including pericardial and pleural effusion, sicca syndrome, calcinosis and watermelon stomach, are presented. ​Practical Management of Systemic Sclerosis in Clinical Practice describes a range of problems and clinical items encountered by a variety of medical professionals who encounter these patients. It is a valuable resource for rheumatologists, immunologists, specialist nurses and primary care professionals.

This book reviews the basics of pulmonary functional imaging using new CT and MR techniques and describes the clinical applications of these techniques in detail. The intention is to equip readers with a full understanding of pulmonary functional imaging that will allow optimal application of all relevant techniques in the assessment of a variety of diseases, including COPD, asthma, cystic fibrosis, pulmonary thromboembolism, pulmonary hypertension, lung cancer and pulmonary nodule.Pulmonary functional imaging has been promoted as a research and diagnostic tool that has the capability to overcome the limitations of morphological assessments as well as functional evaluation based on traditional nuclear medicine studies. The recent advances in CT and MRI and in medical image processing and analysis have given further impetus to pulmonary functional imaging and provide the basis for future expansion of its use in clinical applications. In documenting the utility of state-of-the-art pulmonary functional imaging in diagnostic radiology and pulmonary medicine, this book will be of high value for chest radiologists, pulmonologists, pulmonary surgeons, and radiation technologists.

This book reports on research findings and practical lessons featuring advances in: digital and interaction design; graphic design and branding; design strategies and methodologies; design education; society and communication in design practice; and other related areas. Gathering the proceedings of the 4th International Conference on Digital Design and Communication, Digicom 2020, held virtually on November 5-6, 2020, the book describes cutting-edge perspectives on and analysis of and solutions to challenges digital communication is currently presenting to society, institutions and brands. It offers a timely guide and a source of inspiration for designers of all kinds, including graphic, digital and web designers, UI, UX and social media designers, and to researchers, advertisers, artists, and entrepreneurs, as well as brand or corporate communication managers.

This book addresses essential principles of research according to the scientific method for medical imaging technology research. The scope of this book covers the nature of scientific research; quantitative and qualitative approaches essentials; research planning; literature review fundamentals; research methods; data collection, analysis, and interpretation; and communicating research findings. The book meets the educational requirements on Research Principles and Concepts (for entry to practice) of the following professional radiologic technology associations: the American Society of Radiologic Technologists (ASRT), the Canadian Association of Medical Radiation Technologists (CAMRT), the College of Radiographers in the United Kingdom, and radiography societies and associations in Asia, Australia, Europe, and Africa. This is an ideal book for radiologic technologists, nuclear medicine technologists, and radiation therapists seeking to get started in research in their profession. Additionally, biomedical imaging engineering technologists, radiologists, and medical imaging physicists may use this as a “guiding principles” textbook.

This book provides a practically applicable guide to the all the different imaging modalities used in the diagnosis and management of ENT & Head and Neck patients. It bridges the gap in understanding between surgeons treating ENT & Head and Neck conditions and radiologists who oversee the process of scan requests, interpretation and delivering reports that best inform the subsequent management. Chapters cover a variety of sub-specialist areas including plain films, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), auditory implantation, paediatrics, head and neck cancer, trauma, three dimensional (3D) reconstruction and rehabilitation including swallow. This book facilitates surgeons and radiologists to further develop their understanding of each other's perspectives on clinical decision-making and appropriately interpreting the outputs from a range of imaging modalities. Head and Neck Imaging: A Multi-Disciplinary Team Approachis a resource well-suited to all trainees, residents, consultants who use these techniques to treat patients with head and neck symptoms. Furthermore, it is vital for those individuals preparing for exams in disciplines such as ear nose and throat, maxillofacial surgery and radiology.