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Thought as a primary reference on cutaneous ulcer management, written in a clear style by multidisciplinary experts and carefully edited and crafted, this volume covers of the complex topic of Wound Care, highlighting Pearls and Pitfalls in Skin Ulcer Management: from anatomy, epidemiology, pathogenesis and prevention, to diagnosis and selection of the best treatment options. This book also offers practical'how to do'advice and includes sections on cleaning and dressing, Negative-pressure wound therapy (NPWT), the latest on dermal substitutes, Platelet Rich Plasma (PRP) and Minimal Invasive Modality (MIMo) in burns. Specific parts illustrate how to assess a clinical wound measurement, and the role played by imaging and telemedicine. The section on infection ranges from diagnosis and classification to drug treatments, diabetic foot management and osteomyelitis. Specific chapters focus on surgical intervention, ranging from grafting and micrografting, to surgical debridement, different reconstructive options and lower limb ulcers. The final part offers additional knowledge, as for example wound and scars in aesthetic surgery, in advanced illnesses or recurrence, pain management, rehabilitation and posture restoration. While moving from plastic surgery, this truly interdisciplinary and richly illustrated volume spans over many disciplines, and will be highly valued by all specialists that face ulcer wound care in their clinical experience, from plastic and vascular surgeons to other wound specialists and related health professionals, as physiotherapists and nurses. Written in a clear style and in an easy-to-read format, this volume will also be of use for courses and university masters teaching how to manage this complex pathology.

This reference book provides a comprehensive overview of natural gums, resins, and latexes of plants with a focus on their chemistry, biological activities, and practical uses. The content is divided into five main sections each of which contains chapters contributed from valuable experts in their field. Naturally occuring plant products have quite diverse applications in many different industries. The book aims to highlight the important aspects of plant-based gums, resins and latexes as well as provide a strategic framework for further research and development activities on these bioproducts. It will appeal to a broad audience such as biologists, pharmacologists, pharmacists, food technologists and medical practitioners. It is also a useful resource for research investigators of the healthcare industry, academia and students of biomedical sciences.

This book compiles all relevant information regarding fundamental concepts and advanced techniques related to the applications of minimally invasive procedures in periodontal and implant therapy facilitated with the operating microscope. Microsurgical therapy, wound healing principles as well as biomechanical and design aspects of micro-instruments and suturing armamentarium are discussed. The book offers information that is usually scattered in the dental and medical literature and not only hard to compile but also to frame in the appropriate clinical categories. Its unique emphasis on ergonomics (patient, operator and assistant positioning) and collaboration techniques like four to six hand assisting make this work unique. Each topic is discussed by world renowned experts in the field. The book is a valuable resource for the dental society including general dentists, periodontists, oral surgeons and implantologists.

This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.

This book examines the topic of learning design from a human, interactive, and collaborative perspective. A variety of pedagogic and instructional modalities are thoroughly investigated as methodologies for creating functional and effective designs for students. The book is appropriate for all levels of teaching and learning, but special attention is paid to the special requirement of higher education, graduate education and post-graduate classrooms.Within the research chapters are embedded numerous examples, case studies, and implementation guides. The book is a scholarly yet practical guide to learning design and everyone from educational researchers in all areas of educational technology to instructional designers and instructional technologists will find it useful and inspiring at once.

This book covers the explosion of new information about the relationship between the brain and its blood supply since the first edition was published in 2009. With new knowledge and its impact on clinical care, neurovascular neuropsychology has become a recognized sub-specialty that has been integrated into health care systems in the US and abroad. The second edition brings to this larger audience the latest word on these matters, with new emphasis on women's issues, relevance to the pediatric population, insights from modern imaging, and advances in medical and surgical treatments such as heart transplantation, cardiovascular transarterial therapies, and noninvasive brain stimulation in connection with neurocognitive outcomes.

Proceedings of the NATO Advanced Study Institute on New Trends and Applications of Photoelectrochemistry and Photocatalysis for Environment Problems, Cafelù, Palermo, Italy, September 6-18, 1987

Like its preceding editions, this atlas is an indispensable guide to the field of neurology, featuring the most clinically essential images and figures. Chapters offer insight and research written by deeply practiced, knowledgeable neurologists that is supplemented with detailed imagery, tables, algorithms, and delineative drawings. Topics covered include developmental and genetic diseases, neuroendocrine disorders, critical care neurology, cerebrovascular disease, dementias, behavioral neurology, neuro-oncology, movement disorders, epilepsy, neuromuscular diseases, infectious diseases, neuroimmunology, neurotoxic disorders, and headache. The authors also delve into specific issues currently prevalent in neuroscientific research, including Alzheimer's disease, dementia, Machado-Joseph disease, Huntington's disease, and brain scanning with PET and fMRI. The Atlas of Clinical Neurology, 4th Edition serves as a comprehensive and premier visual resource for neurologists.

The book deeply focuses on the epidemiology, diagnostics, therapy and molecular basis of canine and feline dementia or cognitive dysfunction syndrome. The aim is to provide a broad overview of the current knowledge on canine and feline dementia. Experiences of clinicians are appropriately linked with current scientific knowledge in a readily comprehensible form. In the first three chapters we describe the clinical pictures of canine and feline dementia, discuss the medical causes of the disease and its phenotypic variability. In the 4th chapter we introduce the dog as an appropriate animal model for human Alzheimer's disease progression. Then we shed light on the neuropathological hallmarks of canine and feline dementia. For the first time we touch upon the modern diagnostic approaches based on the neuroproteomic technological progress. Last but not least, we address the current pharmacological and non-pharmacological approaches for therapy and risk and protective factors of feline and canine dementia. The book addresses clinicians, researchers, university teachers and graduate students in veterinary neurology and medicine.

Contributions featuring the chemistry and applications of a family of macrocyclic compounds collectively known as'calixarenes'are presented in this edited volume. The arsenal of structures based on calixarenes provides tools which are effective in numerous areas of supramolecular chemistry. The Editors have compiled a timely volume which contains up to date, high calibre contributions from a large number of international authors. A broad perspective on the progress and future of calixarene chemistry is presented. Aimed at students and researchers active in Supramolecular Chemistry.

Present day heterogeneous catalysis is rapidly being transformed from a technical art into a science-based technology. A major contribution to this important change is the advance of surface spectroscopic techniques able to characterize the complex surfaces of the heterogeneous catalytic system. The Advanced Study Institute (on which the current proceedings is based) has as its primary aim the bringing together of a variety of lecturers, outstanding in those fields of experience, to enable a broad coverage of different relevant approaches. Not only catalyst characterization but also catalytic reactivity had to be covered in order to relate catalyst properties with catalyst performance. Since modern catalysis relates catalytic performance to microscopic molecular catalyst features, theoretical electronic aspects also had to be included. The Advanced Study Institute had a unique feature in that it brought together physicists, catalytic chemists and chemical engineers whom rarely directly interact. From physics especially new experimental possibilities of beams were emphasized. At present it is possible to obtain very detailed information on model catalysts, whilst the applications to practical catalysts are gaining rapidly in sophistication. Apart from the plenary lectures, the Institute included'hot topics'to highlight special developments and offered participants the opportunity to present contributed papers (either orally or as a poster). These contributions formed an integral part of the summer school and significantly enhanced the interaction between participants. Inclusion of the hot topics and contributed papers in these proceedings give them an added topical value.

Dieses Buch stellt in kurzer und übersichtlicher Form Leitlinien zur Diagnostik und Therapie von psychiatrischen Erkrankungen im Alter dar. Aufbauend auf den langjährigen Erfahrunges des Autors mit dieser Patientengruppe, die aufgrund der demographischen Entwicklung stark zunimmt, werden Leitlinien zu medikamentösen und psychotherapeutischen Behandlungsmöglichkeiten dargestellt. Checklisten und Flußdiagramme erleichtern die diagnostischen und therapeutischen Entscheidungen beim Umgang mit diesen Patienten.

Y. Fujimori, Symposium Programme Committee Chair, and Faculty Member, International Space University e-mail: fujimori@isu. isunet. edu M. Rycroft, Faculty Member, International Space University e-mail: rycroft@isu. isunet. edu Building on the foundations provided by the International Space Station, now partially constructed and already in use in low Earth orbit, what will be the future directions of human spaceflight? This was the key question discussed from many viewpoints - technical, entrepreneurial, governmental, legal - at the seventh Annual Symposium held in Strasbourg, France, early in June 2002. Many ideas on the'whys'and the'hows'of our future exploration of the final frontier were put forward in a stimulating environment. The unique perspective of the International Space University (ISU) - namely an interdisciplinary, international and intercultural perspective - enhanced both the presentations and the discussions. More than 150 people attended the Symposium, including the current members of the Master of Space Studies class who are attending an 11 month course at ISU. They are young professionals and postgraduate students who develop in-depth some part of the broad Symposium theme in their parallel Team Projects. Their final reports will be completed at the end of July 2002, and will be published independently. 1 Beyond the ISS: The Future of Human Spaceflight Keynote Address: A Summary The Need for a New Vision E. Vallerani, Advanced Logistic Technology Engineering Center, The Italian Gateway to the ISS, Corso Marche 79, Torino 10146, Italy e-mail: vallerani. ernesto@spacegate-altec.

This volume constitutes the proceedings of the Fifth International Conference on Multi-Objective Programming and Goal Programming: Theory & Appli­ cations (MOPGP'02) held in Nara, Japan on June 4-7, 2002. Eighty-two people from 16 countries attended the conference and 78 papers (including 9 plenary talks) were presented. MOPGP is an international conference within which researchers and prac­ titioners can meet and learn from each other about the recent development in multi-objective programming and goal programming. The participants are from different disciplines such as Optimization, Operations Research, Math­ ematical Programming and Multi-Criteria Decision Aid, whose common in­ terest is in multi-objective analysis. The first MOPGP Conference was held at Portsmouth, United Kingdom, in 1994. The subsequent conferenes were held at Torremolinos, Spain in 1996, at Quebec City, Canada in 1998, and at Katowice, Poland in 2000. The fifth conference was held at Nara, which was the capital of Japan for more than seventy years in the eighth century. During this Nara period the basis of Japanese society, or culture established itself. Nara is a beautiful place and has a number of historic monuments in the World Heritage List. The members of the International Committee of MOPGP'02 were Dylan Jones, Pekka Korhonen, Carlos Romero, Ralph Steuer and Mehrdad Tamiz.

This book focuses on diversity, culture, and ethnicity as they relate to psychological assessment of Hispanics. It is a how-to guide for clinicians, researchers, and instructors working with Hispanic clients. Each chapter contains an overview of cultural considerations needed for assessing the Hispanic client followed by a specific exploration of the assessment measures available and the research that has been conducted on these measures with Hispanic participants. An exploration of the strengths and limitations of each assessment measure is included. Considering that ethnocultural minority individuals who are of Hispanic/Latino origin make up the largest ethnocultural minority group in the United States, guidelines for working with this population are a must. Given that a large subset of this percentage is composed of immigrants many of whom do not speak English or who have learned English as a second language, special considerations for effective psychological assessment are neccessary.This book fills a gap in the scientific literature by consolidating the research on psychological assessment with Hispanic samples into one comprehensive volume and providing simple recommendations for the psychological assessment of Hispanic clients. An exploration of the general psychological assessment domains (e.g., personality, intelligence) is included with references to research on the major assessment measures used in the field. A more specific exploration of psychodiagnostic assessment measures follows, including the assessment of mood disorders, anxiety disorders, sexual dysfunction, psychosis, etc. Several chapters are dedicated to specialized assessment, including neuropsychological assessment, forensic assessment, and school-based assessment, overall creating the most comprehensive, up-to-date, research-based compendium of psychological assessment measures for use with Hispanic clients.

The promise of chemotherapeutic control in the field of oncology seemed, in the beginning, no less bright than it had proven in the field of bacterial disease, and, therefore, its failures were felt all the more. Despite the serendipitous discoveries and inspired insights which tantalized us with striking remissions, or the rare tumors which proved to be fully susceptible to a given agent, in the main, there has been either total failure or a painfully slow acquisition of an armamentarium against a limited number of malignancies. To expect more, however, was the result of ignorance of the malignant cell, for, as has been described in the previous volumes of this series, the exploitable differences between malignant and normal cells are few or undiscovered.'Differences'is the'numerator'in this formula, but'exploitable'is the operational term, for, although a great number of differences bet\\\een normal and malignant cells have been described, rarely are these differences observed in a vital metabolic pathway or a crucial macromolecu­ lar structure. Essentially, the basic metabolic pathways and nutritional require­ ments for :lOrmal and malignant cells are the same, resulting in the fact that no chemotherapeutic agent can successfully inhibit a function in the majority of malignant cells without adversely affecting a similar function in the normal cell. It was, therefore, naive to expect a'magic bullet'which would select the malignant cell and destroy it.

Although there are numerous technical-scientific books on breast cancer in the global bibliography, such books deal exclusively with the nature of the disease in majority populations of the Western societies, with little or no reference to the nature of the disease in the minority populations in such societies. Similarly, the nature of breast cancer in black women of the less privileged societies, and in women of ethnic groups living in countries of similar socio-economic status, is virtually unknown. For various epidemiological reasons, breast cancer incidence is rapidly increasing in these counties, more so than currently is the case in developed countries. Thus, the global burden of cancer is shifting gradually to these areas of the world, and may equal or even surpass the breast cancer burden in the Western societies within the foreseeable future. This book is unique because it bucks the trend of virtually all other breast cancer books by addressing specifically the breast cancer experience of women of African descent and their lifestyle counterparts in other societies of the world.