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The successful book of andrology now in a new edition! This book gives a complete, interdisciplinary overview of the central topics of andrology, infertility, hypogonadism, contraception and erectile dysfunction. It contains detailed information on the clinical practice of couple treatment, andrology-relevant gynecology and modern methods of assisted fertilization, psychological factors of infertility, endocrinology and reproductive functions of the aging man as well as on an important sub-area of ​​andrology, the male contribution to contraception. In addition, the relevant scientific foundations (including molecular biology and genetics) are also covered. Completely revised and updated according to the latest scientific research, the new edition represents a reference for andrology, which no doctor who deals with the topic can miss. For andrologists, practitioners and residents, urologists, dermatologists and internists who deal with the area of​​andrology and male reproductive medicine.

Seit Jahrzehnten der unangefochtene Bestseller für die Psychopharmakotherapie!Verlässlichkeit und Kompetenz zeichnet auch die 14. Auflage des Kompendiums aus. In der Neuauflage wurden sämtliche Inhalte sorgfältig überarbeitet und auf den neuesten Stand gebracht. Selbstverständlich finden Sie alle neuen Präparate mit den aktuellsten Empfehlungen und Bewertungen und die Berücksichtigung der DSM-5 Klassifikation.Das „Kompendium der psychiatrischen Pharmakotherapie“ ist der unverzichtbare Leitfaden für die Psychiatrie. Nirgendwo sonst findet man so komprimiert alles Wissenswerte rund um die Psychopharmakotherapie PLUS alles Wesentliche zu den einzelnen psychischen Störungen.

This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics.It is a useful resource for graduate and post-graduate students in the field of Forensic Science.

This book describes the different aspects of ischemic heart disease, one of the leading causes of death in industrialized countries, and whose growing prevalence represents a major challenge in terms of short- and long-term management and surveillance. This volume offers a comprehensive discussion of the state-of-the-art diagnostic imaging options, of disease risk stratification, selection of candidates for surgical intervention, percutaneous revascularitation, mechanical assist devices implantation. Recently, the morbidity and mortality of ischaemic heart disease have substantially improved because of the progress in therapeutic strategies, represented by the dramatic evolution of percutaneous coronary interventions, that are carefully described in the volume, together with all the other most recent treatment options: from medical therapy to conventional surgery, minimally invasive surgery, surgery of ischemic complications. The biggest challengein the next years is, however, to reduce the incidence of coronary artery disease worldwide.This highly illustrated, case oriented reference book is aimed at cardiology fellows in training, while also helpful to surgeons, cardiologists, imaging specialists, interventional cardiologists, as well as other clinicians and students involved in the diagnosis and treatment of ischemic disease.

This book provides a practically applicable guide to the applications of pharmogenomics across medicine. Background information is provided on the mechanisms associated with membrane transporters, drug-metabolizing enzymes and their importance in pharmagenomics. Detailed guidance is subsequently presented on how to apply these techniques in disciplines including cardiology, gastroenterology, oncology, transplantation surgery, infectious diseases, anesthesia and analgesia, neurology, psychiatry, primary care, and public health. Clear easy-to-follow instructions are given on how to use big data technologies and public health databases in day-to-day clinical practice. Pharmacogenomics in Clinical Practice concisely covers how pharmacogenomic technologies and techniques can be applied in daily medical practice. It is therefore an ideal up-to-date resource for any medical practitioner, trainee or researcher across all medical disciplines whowant to better understand how to use these techniques.

This handbook provides a detailed overview of the emotional, physical, and social implications of anger, aggression, and violence. The book covers the recognition, diagnosis, and evaluation of these areas, aiming to understand the aetiology of these behavioral features to assist with prevention and cure. The book is divided into eight sections: Placing Aggression, Anger, Aggression and Violence In ContextCauses and Precipitation of Anger, Aggression and ViolenceFeatures of Anger, Aggression and ViolenceAnger, Aggression and Violence in Defined Disorders and ConditionsPhysical Measures of Pathology and Insights: GeneticsPhysical Measures of Pathology and Insights: Non-GeneticTreatments and TherapiesMethods and Techniques Handbook of Anger, Aggression, and Violence will be of use for behavioral scientists, psychologists, psychiatric nurses and doctors, neurologists, health scientists, general practitioners, research scientists and all those interested in altered behavior.

Even though research on testosterone is increasing, there is still much controversy regarding its physiology and clinical use. This book provides a broad overview on testosterone, from its basic features to the most recent evidence of clinical applicability. In addition, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. The testes are vital organs for reproduction of the human species, besides being the main source of testosterone production in men. Although not essential for survival, these singular structures represent the essence of male biological function. Testosterone is the most important testicular androgen in men. Low serum testosterone levels are associated with cardiovascular morbidity, metabolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Also, there is increasing evidencethat serum testosterone is a major biomarker status of men's health in general. Hypogonadism in a male refers to a decrease in one or both of the two major functions of the testes: sperm production or testosterone production. These abnormalities can result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism). Currently, the clinical features of male hypogonadism are sufficiently well-recognized, the causes are well-known, and the tests of the hypothalamic-pituitary-testicular axis are accurate enough for the diagnosis in most patients. Testosterone, the focus hormone of this book, is used in different forms and routes of administration. Several authors unravel its peculiarities and assist in choosing the most suitable form in each case, as well as the possible risks of its misuse or even abuse in men and women, seeking alternatives to help patients in this situation.

Das Standardwerk der Andrologie - jetzt komplett aktualisiert! Das Buch gibt einen vollständigen, interdisziplinären Überblick aller Themen der Andrologie, u.a. · der Infertilität, · des Hypogonadismus, · der männlichen Kontrazeption, · der erektilen Dysfunktion und · der Varianten der sexuellen Differenzierung. Der Leser erhält detaillierte Informationen über · die Physiologie der Hoden- und Spermienfunktion · die Diagnostik und Therapie einschl. operativer Verfahren in der Andrologie · die klinische Praxis der Paarbehandlung, · relevante Fakten aus der Gynäkologie, · moderne Verfahren der assistierten Fertilisation · psychologische Faktoren der Sexualität und Infertilität · Umwelteinflüsse auf die Fertilität · Therapie mit Testosteron und Missbrauch · endokrinologische und reproduktive Funktionen des alternden Mannes. · Fertilitätsprotektion · rechtliche und ethische Grundlagen der Andrologie Zusätzlich werden die relevanten naturwissenschaftlichen Grundlagen – einschließlich Molekularbiologie und -genetik – abgedeckt. Komplett nach dem neuesten Stand der wissenschaftlichen Erkenntnis überarbeitet, aktualisiert und praxisorientiert ist der Nieschlag das Standardwerk der Andrologie, an dem keine Ärztin und kein Arzt, der sich mit dem Thema befasst, vorbeikommt. Für Andrologen und Teilnehmer der Zusatzbezeichnung'Andrologie', Urologen, Dermatologen und Internisten, die sich mit dem Gebiet Andrologie beschäftigen. Für Reproduktionsbiologen und Reproduktionsmediziner mit Interesse an der Paarbehandlung.

Das Buch vermittelt aktuell und umfassend das Wissen auf dem Gebiet der Neuro-/Psychopharmakologie. Um ein tieferes Verständnis der Therapieprinzipien sowie der Besonderheiten der medikamentösen Behandlung bei Kindern und Jugendlichen zu erhalten, werden im ersten Teil die Grundlagen der Neuro-/Psychopharmakologie dargelegt. Zudem werden rechtliche und ethische Fragen im Praxisalltag eingehend erörtert. Der zweite Teil behandelt ausführlich die verschiedenen Arzneistoffgruppen. Im dritten Teil wird die störungsspezifische und symptomorientierte Medikation praxisorientiert beschrieben und kritisch bewertet, so dass der Arzt über eine klare Handlungsanleitung verfügt. Die vierte Auflage wurde aktualisiert und auf den neusten wissenschaftlichen Stand gebracht. Dieses Nachschlagewerk besticht durch die komprimierte und einheitliche Darstellung mit vielen zweifarbigen Tabellen, Schemata und Abbildungen. Es wendet sich an Kinder- und Jugendpsychiater und -psychotherapeuten, Pädiater, Allgemeinmediziner, Psychologen, Pflegekräfte und Lehrer.

This book uniquely discusses an approach to illnesses for which the causes are unknown. It fills the gaps in the literature by relaying research on functional illness, identifying and assessing various options, and indicating some decision-making suggestions that should help clinicians and patients think about therapy. Special considerations for functional illness include “probability” explanations based on the experience of others, serious consideration of the severity of symptoms before treatments are applied, and balancing the risks, costs, and consequences of treatment; including the patient's thoughts and attitudes is critical for success in treating functional illness. Unique and comprehensive, Functional Illness is an invaluable reference for medical physicians of all specialties who wish to understand better and identify functional illness symptoms.

Substance misuse and addictions are a public health issue. They affect the well-being of each community and nation as a whole. It is, therefore, necessary to identify, educate, and treat individuals who are addicted to substances. Policies and procedures go hand-in-hand with public health education and safety. The science behind the public health issues of one drug may be applicable to other drugs as well. However, marshalling all of the aforementioned information into a single source is somewhat difficult due to the wide array of material. The Editors address this by compiling the research in this single reference work that serves as a'one-stop-shopping'approach to everything readers need to know about the scientific basis of public health and addictions and agents of misuse.Apart from active agents that have a plant or chemical basis, there is a need to consider that there are other forms of addiction which may havecommon modes of causality or prevention. These include food addiction, gaming, gambling, and other non-drug addictions. These types of addiction may be related to the addiction of drugs.The Handbook of Substance Misuse and Addictions: From Biology to Public Health offers a holistic understanding of the relationship between public health and substance misuse. The text provides a common platform upon which other forms of addiction or substance misuse can be understood and treated. Addiction processes involve understanding the biological processes as well as behavior, psychology, sociology, and public health, all of which are interlinked. This Handbook is a useful reference for lecturers, students, researchers, practitioners, and other professionals in public health, addiction science, epidemiology, health education, health promotion, and health sciences.

This book explores suicide prevention perspectives from around the world, considering both professionals'points of view as well as first-person accounts from suicidal individuals. Scholars around the globe have puzzled over what makes a person suicidal and what is in the minds of those individuals who die by suicide. Most often the focus is not on the motives for suicide, nor on the phenomenology of this act, but on what is found from small cohorts of suicidal individuals. This book offers a tentative synthesis of a complex phenomenon, and sheds some light on models of suicide that are less frequently encountered in the literature. Written by international experts, it makes a valuable contribution to the field of suicidology that appeals to a wide readership, from mental health professionals to researchers in suicidology and students.

Dieses Buch bietet einen umfassenden Überblick über den aktuellen Wissensstand zu Neuropathologien infolge von Drogenmissbrauch. In den ersten Kapiteln erhält der Leser detaillierte Informationen über die neurobiologischen Grundlagen des Drogenmissbrauchs und die Ergebnisse von Neuroimaging-Studien bei Drogenabhängigen. Der Schwerpunkt des Werks liegt auf neuropathologischen Befunden bei Drogenabhängigen für die vorherrschenden Substanzen, zu denen Cannabis, Opiate, Kokain, Amphetamin, Methamphetamin und ein breites Spektrum von Designerdrogen gehören. Diese Befunde werden durch histologische Abbildungen untermauert und im Zusammenhang mit aktuellen wissenschaftlichen Veröffentlichungen diskutiert. Das Buch enthält auch ein Kapitel, das sich speziell an Kliniker richtet und die Auswirkungen auf die weitere Therapie aufzeigt. Eine unverzichtbare Lektüre für Neuropathologen, Neurologen, Neuroradiologen und Psychiater sowie für andere Angehörige der Gesundheitsberufe und Wissenschaftler,die sich für das Problem des Drogenmissbrauchs interessieren und engagieren.

This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.

This book discusses the current and future impact of cellular and molecular medicine (CMM) on anesthesiology and perioperative medicine. It covers the topic from a translational perspective and describes the relevance of CMM to daily clinical practice. Taking a bench-to-bedside approach, chapters examine topics including perioperative acute and chronic management, perioperative organ protection, and novel pharmaceuticals. Personalized Medicine in Anesthesia, Pain and Perioperative Medicine is aimed at anesthesiologists and pain physicians, and will also be of interest to pharmacists and those working in cellular and molecular medicine.

This text provides a critical look at the state of the evidence in the most compelling areas of laryngology. Rather than being a comprehensive text covering every single possible area, it focuses on published works in the 9 areas that are of the most interest to laryngologists as well as speech pathologists, general otolaryngologists, and head and neck oncologists managing laryngologic issues. The state of the literature is succinctly summarized and tabulated in each area, allowing the reader to see which areas have high-grade evidence (Levels 1 or 2) to support decision making, and which areas are in need of better quality studies. Each chapter is divided into three main sections: Diagnosis and Pathophysiology, Surgical management, and Non-surgical management. This makes it easier for the reader to browse to the area of interest in each section and to find the evidence basis for a given concept.Evidence-Based Laryngology will be an invaluable resource to otolaryngologists, residents, speech-language pathologists, and other clinicians who manage laryngological problems and would like to know the evidence basis behind different treatment options.

This book provides a comprehensive overview of the current state of knowledge concerning neuropathologies resulting from drug abuse. The first chapters offer readers detailed information on the neurobiological basics of drug abuse and the results of neuroimaging studies in drug abusers. The focus of the book is on neuropathological findings in drug abusers for the predominant substances, which include cannabis, opiates, cocaine, amphetamine, methamphetamine and a broad spectrum of designer drugs. These findings are supported by histological illustrations and discussed in connection with recent scientific publications. A chapter specifically addressing clinicians is also included, and highlights the implications for further therapy. The book is essential reading for neuropathologists, neurologists, neuroradiologists and psychiatrists, as well as other health professionals and scientists interested and engaged in the problem of drug abuse. Although a great deal of datahas been derived from animal models and from human neuroimaging studies, little is known about the morphological effects of drug abuse on the human brain. In recent years, fundamental drug-induced effects on the cellular elements of the brain have been detected. These alterations might not only be the substrate of the neuroimaging data but might also have implications for clinical research and therapy. In addition, drug abuse may induce premature neurodegeneration.

This textbook is intended to give an introduction to neuroscience for students and researchers with no biomedical background. Primarily written for psychologists, this volume is a digest giving a rapid but solid overview for people who want to inform themselves about the core fields and core concepts in neuroscience but don't need so many anatomical or biochemical details given in “classical” textbooks for future doctors or biologists. It does not require any previous knowledge in basic science, such as physics or chemistry. On the other hand, it contains chapters that do go beyond the issues dealt with in most neuroscience textbooks: One chapter about mathematical modelling in neuroscience and another about “tools of neuroscience” explaining important methods. The book is divided in two parts. The first part presents core concepts in neuroscience:Electrical Signals in the Nervous SystemBasics of NeuropharmacologyNeurotransmitters The second part presents an overview of the neuroscience fields of special interest for psychology:Clinical NeuropharmacologyInputs, Outputs and Multisensory ProcessingNeural Plasticity in HumansMathematical Modeling in Neuroscience Subjective Experience and its Neural Basis The last chapter, “Tools of Neuroscience” presents important methodogical approaches in neuroscience with a special focus on brain imaging. Neuroscience for Psychologists aims to fill a gap in the teaching literature by providing an introductory text for psychology students that can also be used in other social sciences courses, as well as a complement in courses of neurophysiology, neuropharmacology or similar in careers outside as well as inside biological or medical fields. Students of data sciences, chemistry and physics as well as engineering interested in neurosciencewill also profit from the text.

Addiction is increasingly being recognized as a major global public health issue, and an ever-growing number of medical specialties, psychological and social science training programs, and professional associations are including addiction as part of their training and continuing education curricula. The first edition of this book presented an overview of the spectrum of addiction-related problems across different cultures around the globe. Sharing the experience and wisdom of more than 260 leading experts in the field, and promoted by the International Society of Addiction Medicine, it compared and contrasted clinical practices in the field of addiction medicine on the basis of neurobiological similarities as well as epidemiological and socio-cultural differences.Building on the success of this inaugural edition, and taking into account the formal and informal comments received as well as an assessment of current need, this textbook presents general updated information while retaining the most requested sections of the first edition as demonstrated by the number of chapter downloads. It also provides a basic text for those preparing for the ISAM annual certification exam. Written by some 220 international experts, it is a valuable reference resource for anyone interested in medicine, psychology, nursing, and social science.

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the coretopic: from social and philosophical to gender-related aspects.It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner's offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.

Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies. Furthermore, the interest of saliva as a diagnostic, prognostic and monitoring biofluid is forced by its non-invasive nature being of easy and inexpensive sampling, involving only minimal discomfort and allowing the collection of multiple/repeated specimens at anytime, anywhere and without need for specialized staff. In this contributed volume, the authors bring together, summarize and reflect the generated knowledge about saliva as a source of biomarkers for health and welfare evaluation in humans and animal models. This volume also highlights the importance of confounding factors, such as sampling methods, flow, total protein content, contamination, or storage. This book will serve as a manual for graduates, practitioners and researchers by providing general ideas about the possibilities and utilities of saliva in clinical practice or investigation, and indicating the main cautions each should have in mind before saliva usage.

This updated volume on clinical forensic medicine covers the topics required for forensic healthcare professionals working in general forensic medicine and sexual offence medicine. All chapters have been reviewed and revised to reflect how the provision of forensic medical services has changed since the previous edition with multidisciplinary teams working in the custodial environment, comprising doctors, nurses, and paramedics and those practitioners providing sexual offence examinations.New and updated topics include: the increasing importance of photo documentation by health care professionals; updated information on strangulation, torture; a review of bite mark injuries; the explosion of Novel Psychoactive Substances worldwide; the changing patterns of deaths in custody and deaths following police contact; and the introduction in various jurisdictions of legal limits for drugs based on zero tolerance or a risk based approach.Written by a team of experts, the new edition of this book is a valuable resource for forensic healthcare professionals including doctors, nurses and paramedics working in general forensic medicine and sexual offence medicine, as well as emergency physicians, pediatricians and gynaecologists.

This comprehensive text summarizes what is known about the myriad of different neurological conditions that cause dysfunction of communication, swallowing, and breathing as it relates to the upper aerodigestive tract. It serves to provide clinicians and scientists, at all levels of experience, a practical and thorough review of these diseases, their management, and frontiers in science. Chapters are written by experts in these conditions from a broad spectrum of medical specialties in order to create a book that is inclusive of diagnostic and therapeutic considerations that clinicians should think about when caring for patients with these conditions. Neurologic and Neurodegenerative Diseases of the Larynx will be an instrumental resource in guiding clinicians to better recognize the subtle and not so subtle voice, swallowing, and airway manifestations of these diseases, and improve management of patient symptoms and concerns in order to maximize both quality of life and longevity. It will aide otolaryngologists, laryngologists, neurologists, speech language pathologists, and other allied health care professionals in developing a more efficient, evidence-based, patient-focused, and multi-specialty approach to managing these complex and challenging patients.

This book presents the outcomes of the 9th International Workshop on Spoken Dialogue Systems (IWSDS), “Towards creating more human-like conversational agent technologies”. It compiles and provides a synopsis of current global research to push forward the state of the art in dialogue technologies, including advances in the context of the classical problems of language understanding, dialogue management and language generation, as well as cognitive topics related to the human nature of conversational phenomena, such as humor, empathy and social context understanding and awareness.

This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly developing phenomenon.

This comprehensive, practical title invites all clinicians to take a fresh look at the evaluation and management of chronic daily headache (CDH). Developed by a distinguished international panel of experts, the book examines key social and economic issues around CDH and clarifies the diagnosis of CDH disorders, providing an understanding of the underlying biological substrates, offering guidance on the use of diagnostic testing and additional consultations, and outlining treatment strategies with the greatest potential to alleviate the burden of these patients and to provide the highest quality of care. The book fully examines the constellation of symptoms that constitute chronic daily headache, while also discussing the role of behavioral medicine and the important elements involved in taking a good history. The major forms and biology of chronic daily headache are covered, as is the role of diagnostic testing and treatment. The risk factors that lead patients to transform episodic primary headache disorders into the chronic form are examined. Invasive and neuromodulatory techniques are also discussed. A section on the classification of these disorders rounds out this important contribution to the literature. Chronic Headache – A Comprehensive Guide to Evaluation and Management will be of great interest to neurologists, primary care physicians, nurse practitioners, physician assistants, medical students, and other clinicians with an interest in chronic daily headache.

This comprehensive, first-of-its kind title is an indispensable resource for pharmacists looking to learn or improve crucial patient assessment skills relevant to all pharmacy practice settings. Pharmacists'role as health care practitioners is evolving as they are taking a more active part in primary patient care -- helping patients manage their medications and diseases, providing patient education, and, in some jurisdictions, prescribing and adapting medications. To perform their day-to-day duties, pharmacists are best-served using a framework called the patient care process. This framework involves three steps: patient assessment; care plan development and implementation; and monitoring and follow up. Organized in four parts, this practical book begins with introductory chapters regarding the basics of patient assessment and the patient care process. Part II includes a detailed assessment of common symptoms encountered by pharmacists. Part III discusses assessment of patients with various chronic illnesses. Part IV addresses select specialized topics and assessment considerations. An invaluable contribution to the literature, Patient Assessment in Clinical Pharmacy: A Comprehensive Guide will be of great benefit to pharmacists, regardless of their practice setting, and to pharmacy students as well.

This book provides neurologists with a basic knowledge of psychiatric medications. It begins with general principles of psychopharmacology and the frequency of psychiatric illness in neurology patients. It goes on to cover psychoactive drugs in the elderly and treating behavioral symptoms of dementia. There is a special emphasis on drug-drug and drug-diet interactions that may be seen in clinical practice. Neurologists, residents, neuropsychiatrists, neuropsychologists and psychiatrists in training will find this practical guide invaluable in numerous clinical settings.

This book is designed to give clinicians a practical guide to the detection, assessment and treatment of sleep disorders in patients with psychiatric illness in order to better treat both their sleep disorder and their psychiatric disorder. In addition to providing a thorough introduction to the major sleep disorders, it offers clear guidance on how to assess and manage these disorders in patients with a wide range of psychiatric conditions. The role of psychiatric medication and special considerations to be borne in mind when treating psychiatric patients are also addressed. Although it is aimed primarily at psychiatrists, this will also be a useful handbook for sleep clinics and general practitioners who frequently have to manage patients with both psychiatric and sleep disorders.

This comprehensive revision of the invaluable reference presents a rigorous survey of pain and palliative care phenomena across the lifespan and across disciplines. Grounded in the biopsychosocial viewpoint of its predecessor, it offers up-to-date understanding of assessments and interventions for pain, the communication of pain, common pain conditions and their mechanisms, and research and policy issues. In keeping with the current public attention to painkiller use and misuse, contributors discuss a full range of pharmacological and non-pharmacological approaches to pain relief and management. And palliative care is given expanded coverage, with chapters on interventive, ethical, and spiritual concerns.· Pain, intercultural communication, and narrative medicine.· Assessment of pain: tools, challenges, and special populations.· Persistent pain in the older adult: practical considerations for evaluation and management.· Acute to chronic pain: transition in the post-surgical patient. · Evidence-based pharmacotherapy of chronic pain.· Complementary and integrative health in chronic pain and palliative care.· The patient's perspective of chronic pain.· Disparities in pain and pain care.This mix of evolving and emerging topics makes the Second Edition of the Handbook of Pain and Palliative Care a necessity for health practitioners specializing in pain management or palliative care, clinical and health psychologists, public health professionals, and clinicians and administrators in long-term care and hospice.

Due to the fact that Restless Legs Syndrome/Willis-Ekbom Disease is usually a chronic condition, this book aims to provide physicians with the necessary tools for the long-term management of patients with RLS. The first part of the book addresses the various comorbidities and long-term consequences of RLS on life quality, sleep, cognitive, psychiatric and cardiovascular systems, while the second part focuses on the management of long-term treatment and the drug-induced complications in primary RLS and in special populations. Written by experts in the field, this practical resource offers a high-quality, long-term management of RLS for neurologists, sleep clinicians, pulmonologists and other healthcare professionals.

Das umfangreiche Nachschlagewerk von Möller, Laux und Kapfhammer darf zu Recht als Standardwerk für Psychiatrie im deutschsprachigen Raum bezeichnet werden. Die aktuelle Auflage wurde komplett überarbeitet und aktualisiert, zahlreiche Autoren tragen mit ihrem Expertenwissen dazu bei, dass sowohl Ärzte in Weiterbildung als auch Fachärzte für Psychiatrie und Psychotherapie auf alle Fragen umfassende Antworten erhalten. Insgesamt vier Bände enthalten alle Grundlagen der Psychiatrie, Prinzipien der Diagnostik und Behandlung und selbstverständlich einen umfangreichen Teil zu den einzelnen Störungen.Von der Geschichte über Klassifikation, Diagnostik und Therapie aller Krankheitsbilder bis hin zu speziellen Aspekten der Psychiatrie finden Sie hier das gesamte Wissen auf aktuellem Stand.

In diesem sehr praxisnahen Handbuch zur Altersdepression werden sämtliche allgemeinen wie auch sehr spezielle Therapieoptionen übersichtlich und präzise dargestellt. Es wurde höchster Wert auf die Alltagstauglichkeit der Inhalte gelegt, damit Arzt und / oder Therapeut die hier beschriebenen Therapieverfahren schnell anwenden kann. Im ersten Teil des Buchs werden die für das Verständnis der Altersdepression wichtigen Besonderheiten abgehandelt, der zweite Teil umfasst die Therapiemöglichkeiten unter Berücksichtigung der biologischen und psychologischen Bedingungen des Alters, der dritte Teil stellt etablierte und neue Behandlungsrahmen sowie innovative Therapiekonzepte vor.

Research on testosterone is increasing in many senses; however there is still much controversy regarding its physiology and clinical use. This book addresses these topics, providing a broad over­view about testosterone, from its basic fea­tures to the most recent evidence of clin­ical applicability. Also, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. Although not essential for survival, testosterone represents the essence of male biological function, being the important testicular androgen in men. Low serum testosterone levels are asso­ciated with cardiovascular morbidity, meta­bolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Conversely, increased serum levels of testosterone may lead to deleteri­ous events. In general, there is increasing evidence that serum testosterone is a major biomarker status of men's health in general. Testosterone: From Basic to Clinical Aspects is an indispensable reference for all those who seek state-of-the-art knowledge regarding this hormone, from basic issues (including pharma­cology and physiology) through clinical aspects (related diseases and supplementation ther­apy).

This essential reference volume in the field of suicidology brings forth leading-edge conceptualizations of suicidal behaviour by including emerging trends and recent research advances in the field across the globe. It highlights the trajectories of suicidal behaviour, emphasizing the psyche behind attempting suicide, identifying vulnerable groups, and bridging the gap between theoretical underpinnings and application for addressing the aftermath of suicide. The handbook delineates research progress on risk assessment among vulnerable groups of varied milieu. Furthermore, it introduces various avenues of change and well-being. It also addresses important concerns related to terrorism and suicide in the armed forces. This handbook is a comprehensive repository of the latest research synergized with theoretical conceptualizations that pave the way for newer approaches towards management and prevention of suicidal behaviour. It includes contributions by eminent authors acrossthe globe, and is a must-have resource for scholars, academics and professionals in the areas of mental health and social work.

This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms, abnormalities in monoaminergic neurotransmitter mechanisms, glutamatergic release mechanisms, hippocampal neurogenesis, and abnormal immune and cytokine release mechanisms. Many antidepressants that are in clinical use today including the recently introduced novel agentslike agomelatine or other antidepressants cause clinical remission by resynchronizing disrupted circadian rhythms and melatonin receptor functions, enhancing monoaminergic neurotransmission, promoting hippocampal neurogenesis, and regulating immune mechanisms. This book explains various etiological factors that are involved in the pathogenesis of mood disorders and the mechanisms of therapeutic actions of antidepressants including the recently introduced agomelatine and other antidepressants that exhibit rapid onset of action with greater efficacy and fewer side effects..

This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer's Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.

In this book international experts address a range of key current issues relating to suicide. The opening chapters discuss nosology, definitions, clinical determinants, and conceptual models of the suicide process and consider the evidence regarding potential biomarkers of suicide risk based on neuroscientific research. Adopting a neo-Durkheimian perspective, the role of various social factors in the genesis of suicidal behavior is then explored in depth. Practical user-friendly tools that facilitate risk assessment by clinicians are provided, and detailed consideration is given to efficient and innovative strategies for the prevention of suicide and the treatment of suicidal behavior, such as psychotherapy, psychopharmacological approaches, and effective organization of care, including surveillance and the use of online tools. The final part of the book focuses on the need for and development of a personalized approach within the field of suicide prevention.

This progressive reference redefines qualitative research as a crucial component of evidence-based practice and assesses its current and future impact on healthcare. Its introductory section explains the value of sociocultural context in case conceptualization, and ways this evidence can be integrated with quantitative findings to inform and transform practice. The bulk of the book's chapters review qualitative research in diverse areas, including pain, trauma, heart disease, COPD, and disabling conditions, and examine ways of effectively evaluating and applying qualitative data. This seismic shift in perception moves the healing professions away from traditional one-size-fits-all thinking and toward responsive, patient-centered care.Among the topics in the Handbook:·Examining qualitative alternatives to categorical representation.·The World Health Organization model of health: what evidence is needed?·Qualitative research in mental health and mental illness.·Qualitative evidence in pediatrics.·The contribution of qualitative research to medication adherence.·Qualitative evidence in health policy analysis.The Handbook of Qualitative Health Research for Evidence-Based Practice offers health and clinical psychologists, rehabilitation specialists,occupational and physical therapists, nurses, family physicians and other primary care providers new ways for understanding patients'health-related experiences and opens up new ways for developing interventions intended to improve health outcomes.

This technically oriented book on medicine as applied to extreme sports offers broad coverage of the field extending well beyond the usual focus on major trauma and acute injuries. In addition to the injuries and diseases associated with individual extreme sports, this book also addresses the topics of psychology, dermatology, ophthalmology, infectious diseases, physiology, nutrition, training, injury prevention strategies, rehabilitation, doping, treatment in hostile environments, and legal aspects.Innovative and less frequently considered topics are also discussed, such as recent advances in protective equipment and materials, the effects of exposure on whole-body vibration, and cold exposure risk management. More than 60 of the most authoritative experts from across the world have contributed to this book, drawing on their personal experiences and including practical examples whenever relevant. Both subject matter and illustrations have been selected with the utmost care, the latter including photographs of world-class athletes.The book's multidisciplinary approach to the subject ensures that it will be relevant to a wide readership.

This atlas leads the reader through the adult autopsy process, and its common variations, with a large number of high-quality macroscopic photographs and concise accompanying text. It provides a manual of current practice and is an easy-to-use resource for case examination for consent, medico-legal and radiological autopsies.External realities and checks are discussed at the beginning of the book, which goes on to cover specific body cavities and organ systems in detail. The book ends with chapters on topics including forensic autopsies, specialist sampling, toxicology analyses and the radiological autopsy. Atlas of Adult Autopsy is aimed at practicing pathologists, particularly those in training grades. It may also be of interest to anatomical technicians in autopsy suites, as well as parties with a legal interest in autopsy practice.

Dieses Buch vermittelt einen umfassenden Überblick über das aktuelle Wissen auf dem Gebiet der Neuropsychopharmakologie im Kindes- und Jugendalter. Im ersten Teil werden die Grundlagen der Neuro-Psychopharmakologie dargelegt, um ein tieferes Verständnis der Therapieprinzipien sowie der Besonderheiten der Neuro-Psychopharmakologie bei Kindern und Jugendlichen zu erhalten. Rechtliche und ethische Fragen im Praxisalltag werden eingehend erörtert. Im speziellen Teil werden die verschiedenen Arzneistoffgruppen ausführlich behandelt. Im dritten Teil wird die störungsspezifische und symptomorientierte Medikation praxisorientiert beschrieben und kritisch bewertet, so dass der Arzt über eine klare Handlungsanleitung verfügt. Die 3. Auflage wurde aktualisiert und auf dem neusten wissenschaftlichen Stand gebracht. Dieses Nachschlagewerk besticht durch die komprimierte und einheitliche Darstellung mit vielen zweifarbigen Tabellen, Schemata und Abbildungen. Es wendet sich an Kinder- und Jugendpsychiater und -psychotherapeuten, Pädiater, Allgemeinmediziner, Psychologen, Pflegekräfte und Lehrer.