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This updated text provides a concise yet comprehensive and state-of-the-art review of evolving techniques in the new and exciting subspecialty of interventional urology. Significant advances in imaging technologies, diagnostic tools, fusion navigation, and minimally invasive image-guided therapies such as focal ablative therapies have expanded the interventional urologists'clinical toolkit over the past decade. Organized by organ system with subtopics covering imaging technologies, interventional techniques, recipes for successful practice, pitfalls to shorten the learning curves for new technologies, and clinical outcomes for the vast variety of interventional urologic procedures, this second edition includes many more medical images as well as helpful graphics and reference illustrations. The second edition of Interventional Urology serves as a valuable resource for clinicians, interventional urologists, interventional radiologists, interventional oncologists, urologic oncologists, as well as scientists, researchers, students, and residents with an interest in interventional urology.

This book is a collection of contributions honouring Arnon Avron's seminal work on the semantics and proof theory of non-classical logics. It includes presentations of advanced work by some of the most esteemed scholars working on semantic and proof-theoretical aspects of computer science logic. Topics in this book include frameworks for paraconsistent reasoning, foundations of relevance logics, analysis and characterizations of modal logics and fuzzy logics, hypersequent calculi and their properties, non-deterministic semantics, algebraic structures for many-valued logics, and representations of the mechanization of mathematics.Avron's foundational and pioneering contributions have been widely acknowledged and adopted by the scientific community. His research interests are very broad, spanning over proof theory, automated reasoning, non-classical logics, foundations of mathematics, and applications of logic in computer science and artificial intelligence. This is clearly reflected by the diversity of topics discussed in the chapters included in this book, all of which directly relate to Avron's past and present works. This book is of interest to computer scientists and scholars of formal logic.

Bedside Neurological examination is an important tool in diagnosing neurological disorders. Despite significant advances in the investigations available for diagnosing neurological disorders bedside neurological examination remains the cornerstone in diagnosing neurological disorders and should not only be conducted prior to the investigations but should be actually be utilized to plan the appropriate investigations.The book provides a focused account of various aspects of the neurological examination leading to clinical localisation and hence obtaining the neurological diagnosis. It includes topics like'how to obtain a appropriate neurological history','higher mental system examination', examination of speech and various cranial nerves and examination of other systems including motor system, sensory system, reflexes, cerebellar and autonomic nervous system.The book also includes certain interesting topics like'neurological examination of the unconscious patient'and'tricks and tips of neurological localisation. The book is easy to read and memorize due to multiple self explanatory illustrations and important aspects being highlighted in bulleted format. The book will be of extreme help for MD and DNB students of Internal Medicine as well as DM and DNB students of Neurology and DNB and MCH Neurosurgery students, hence covering a fairly large readership base. It will also be read by practising Internal medicine physicians, neurologists and neurosurgeons who may want to revise the basics and tricks of neurological examination and localization

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines.This new volume will increase readers'understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

This is the first of two volumes that together provide a comprehensive analysis of the embryology, normal anatomy, and pathology of the liver and intrahepatic biliary tract as seen on modern diagnostic imaging techniques. In this volume, readers will find fundamental information on embryology, radiological anatomy, and anatomic variants. A thorough introduction is then provided to each imaging technique, including ultrasound, computed tomography, magnetic resonance imaging, nuclear medicine techniques, angiography, and interventional radiology. The remainder of the volume is devoted to non-tumoral pathology of the liver and intra-hepatic biliary tract. For each disease, readers will find full description of the roles of individual imaging modalities and extensive illustration of the imaging appearances. The authors are world-leading experts in the field, and the book will be an ideal reference for all members of the radiology community, from residents to experts. It will also aid clinicians during their daily practice.

This book comprehensively presents all the necessary information health professionals need to become Certified Asthma Educators. Competent asthma educators must possess a number of skills: they must have appropriate and sound medical and pharmaceutical knowledge; be proficient and effective educators who can influence their patients'behaviors for the better; and, finally, they need the administrative and organizational skills needed to set up and run efficient clinics at their places of work. The book is divided into three sections to meet those needs: Asthma: The Fundamentals; The Role of Education; and, The Effective Asthma Educator. The first section covers clinical knowledge of asthma, with chapters including lung structure and function, clinical presentation of asthma, and environmental issues in asthma management. The second section delves into the role of educating patients and teaches readers how to best do that with an integrated approach between physician, educator, and patient. The third section looks further into educating techniques with a view of the learning process, considerations for instruction locations, and the role the educator plays overall. The final chapter in the book presents example cases for readers to assess the knowledge they have learned throughout. This second edition serves as both textbook and study guide for certification as well as a long-term reference publication. It has been fully updated from the previous edition with the latest treatment guidelines, medications, and disease monitoring methods. This is an ideal guide for asthma educators, those seeking NAECB certification, and any health professional involved with individuals who have asthma.

This book gathers new empirical findings fostering advances in the areas of digital and communication design, web, multimedia and motion design, graphic design, branding, and related ones. It includes original contributions by authoritative authors based on the best papers presented at the 4th International Conference on Digital Design and Communication, Digicom 2020, together with some invited chapters written by leading international researchers. They report on innovative design strategies supporting communication in a global, digital world, and addressing, at the same time, key individual and societal needs. This book is intended to offer a timely snapshot of technologies, trends and challenges in the area of design, communication and branding, and a bridge connecting researchers and professionals of different disciplines, such as graphic design, digital communication, corporate, UI Design and UX design.Chapter “Definition of a Digital Tool to Create Physical Artifacts: The Case of the Gamers4Nature Project” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book comprehensively covers a range of pathological cases in clinical cardiology. Chapters are case focused and detail how a patient is diagnosed and treated in a step-by-step format. A range of engaging video clips enhances the reader's appreciation and understanding of how to apply these techniques into their day-to-day clinical practice with special focus on congenital heart disease diagnosis and management.Case-Based Clinical Cardiology presents a range of clinical scenarios across all cardiology disciplines with a particular focus on echocardiography, electrocardiography and cardiac catheterization. Therefore, it is an ideal resource for both the novice and experienced cardiology practitioner seeking an up-to-date selection of cases to test their knowledge.

This book talks about photoplethysmography (PPG) techniques based on computer-aided data processing. In particular, it presents the results of a co-operative Indo-German project on the topic between Indian Institute of Technology at Chennai and RWTH Aachen University. Measuring system design, experimental details and some preliminary results obtained so far within the framework of this project are presented here. From the investigations carried out so far using the PPG sensors in conjunction with breathing sensors, it has been possible to monitor the 0.125 to 0.15 Hz rhythms in the arterial volumetric changes and to study the influence of breathing on them. These rhythms, which according to medical experts have relevance to psychosomatic conditions e.g. stress or relaxation, can also be addressed to by ancient Indian practices like yoga and meditation. This book presents the results of studying the effects of Indian relaxation techniques like pranayama, meditation, etc. in comparison to western relaxation techniques like autogenic training. So far it has been established that the Indian techniques of relaxation like yoga and meditation are very effective in generating low frequency rhythms in the skin perfusion as monitored by optical sensors. According to medical experts, these low frequency rhythms have a very important bearing on the human physiology and have potential therapeutic implications. This book is meant to provide an overview of the current state-of-knowledge and encourage the next generation of scientists/engineers to carry this work forward, especially on the novel PPG application fields that are of growing importance like pain and stress assessment, detection of peripheral venous saturation and local arterio-venous oxygen consumption as well as contactless space resolved skin perfusion studies with modern camera based PPG technology.

The Handbook of Materials Modeling, 2nd edition is a six-volume major reference serving a steadily growing community at the intersection of two mainstreams of global research: computational science and materials science and technology. This extensively expanded new edition reflects the significant developments in all aspects of computational materials research over the past decade, featuring progress in simulations at multiple scales and increasingly more realistic materials models. Thematically separated into two mutually dependent sets – “Methods: Theory and Modeling (MTM)” and “Applications: Current and Emerging Materials (ACE)” – the handbook runs the entire gamut from theory and methods to simulations and applications. Readers benefit from its in-depth coverage of a broad methodological spectrum extending from advanced atomistic simulations of rare events to data-driven artificial intelligence strategies for materials informatics in the set MTM, as well as forefront emphasis onmaterials of far-ranging societal importance such as photovoltaics and energy-relevant oxides, and cutting-edge applications to materials for spintronic devices, graphene, cement, and glasses in the set ACE. The thorough, interconnected coverage of methods and applications, together with a line-up of internationally acclaimed editors and authors, will ensure the Handbook of Material Modeling's standing as an enduring source of learning and inspiration for a global community of computational materials scientists.

This book focuses on thoracic ultrasound, a versatile, diagnostically accurate, low-cost, noninvasive and non-ionizing imaging technique. Thanks to portable devices, the method can be used to provide quick and accurate diagnoses in emergency settings, during transport, or at the patient's bedside in intensive care units. In addition, as a dynamic examination that allows “real-time” assessment, it can be used to optimize diagnoses, the use of respiratory support equipment, surgical interventions and physiopathological assessments, both in critical patients and those with chronic conditions. Lastly, since it avoids ionizing radiation, thoracic ultrasound offers a first-line diagnostic tool for thoracic disease assessment in connection with pregnancy, neonatology and pediatrics. Pursuing a practical approach, this book also addresses the technological components that are needed in order to adequately set up the equipment. This integrated approach provides non-radiologists with essential know-how on using thoracic ultrasound as an extension of their physical examinations. Specific chapters are dedicated to thoracic ultrasound applications in neonatology, pediatrics and emergency medicine, as well as guided procedures and diaphragm function studies. Thoracic ultrasound has been a central element in the editors'clinical and experimental work for several years, and the book also includes contributions by prominent international experts on specific applications. Given its content and scope, the book will be of interest to all medical practitioners seeking a practical approach to thoracic ultrasound.

This extensively updated textbook comprehensively reviews the latest developments in evidence-based critical care. Topics are covered in a case study format with an emphasis on the principles of diagnosis and therapy. Each topic is covered using a variety of case studies and features a case vignette, clinical question and an additional discussion section to clarify areas of particular importance. Topics including cytokine release syndrome, sympathomimetic overdose and palliative care in the intensive care unit have been extensively revised, while new sections focusing on neuromuscular disease and subarachnoid hemorrhages have been added. Evidence-Based Critical Care, 2nd edition is a critical resource for critical care practitioners, fellows, residents; allied health professionals and medical students who wish to expand their knowledge within critical care. The case study-based approach taken in the textbook makes this an idealresource for those preparing for board examinations.

This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation. The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation. This is an invaluable book for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.

Building upon the highly successful 1st edition, this book is a comprehensive review designed to prepare pediatric residents, fellows, and pediatricians for the General Pediatrics Certifying Examination, and for the American Board of Pediatrics Maintenance of Certification. Pediatric Board Study Guide: A Last Minute Review, 2nd edition, covers all aspects of pediatric medicine; each chapter has been updated according to the most recent content specifications provided by the ABP. The 2nd edition provides more illustrations, diagrams, radiology images, and clinical case scenarios to further assist readers in reviewing pediatric subspecialties. New chapter topics include nutrition, sports medicine, patient safety, quality improvement, ethics, and pharmacology. Finally, the book closes with a “Last Minute Review” of high-yield cases arranged in the same sequence as the chapters, providing readers with a concise study guide of critical cases and conditions.Pediatric residents and fellows preparing for the board examination, pediatricians, and pediatric subspecialists preparing for certification maintenance will find Pediatric Board Study Guide: A Last Minute Review, 2nd edition easy to use and comprehensive, making it the ideal resource and study tool.

This book offers a comprehensive overview of all major pathologic conditions involving the lung and mediastinum and the related diagnostic procedures. Oncologic and non-oncologic conditions are reviewed and described in detail, featuring, besides normal anatomy, also high quality images from several modalities (including X-ray, CT, MR and PET), as well as b/w and color illustrations and line drawings. Complications associated with surgical and oncological treatments are also presented in detail with extensive imaging examples. The book provides a thorough coverage of the topic of thoracic imaging, yet considering a concise and synthetic approach essential to optimal learning. The book will be a useful reference guide for the everyday clinical practice of young radiologists, residents and medical students.

This well-illustrated book covers the full range of lung and pleural diseases from the pathologic standpoint. It has been updated from the first edition by including the most recent molecular data for the different lung diseases, tumor as well as non-tumor ones. New diagnostic tests are included, new aspects for the understanding of diseases have been added. Both diseases of adults and pediatric lung diseases are presented. The chapter on lung development has been expanded due to the many new findings being reported since the first edition.The book will serve as an excellent guide to the diagnosis of these diseases, but in addition it explains the disease mechanisms and etiology. Genetics and molecular biology are also discussed whenever necessary for a full understanding. The author is an internationally recognized expert who runs courses on lung and pleural pathology attended by participants from all over the world. In compiling this book, he has drawn on more than 30 years'experience in the field.

This is the first of two volumes that draw on the specialized insights and extensive clinical experience of phoniatric experts in order to offer a basis for the development of concerted European training standards in phoniatrics, with the goal of guaranteeing a high quality of care for European patients in all age groups. The interdisciplinary character of phoniatrics is mirrored in the inclusion of valuable contributions from a range of other medical and non-medical disciplines. This volume focuses on voice disorders and disorders of language and hearing development. In each case a wide range of particular kinds of communication loss are considered. Basic aspects are fully addressed, and guidance provided on diagnostic methods, differential diagnosis, prevention, treatment/rehabilitation, and prognosis. An introductory section also discusses the fundamentals of phoniatrics. The reader will benefit from numerous color photos and tables as well as supplementary electronic material, including audio and video examples. This book is intended for residents and practitioners in phoniatrics and also for ENT physicians, medical students, logopedists, and speech and language pathologists and therapists.

This book serves as an introduction to the dynamic field of radiology for medical students, non-radiology house staff, physician assistants, nurse practitioners, radiology assistants, and other allied health professionals and provides information that ranges from basic radiographic principles to advanced imaging techniques. It begins with a discussion of the fundamental concepts underlying the medical use of imaging modalities such as ultrasound, computed tomography, magnetic resonance imaging, and nuclear medicine. Subsequent chapters are organized by anatomic region and imaging modality that highlight the radiologist's role in diagnosing and treating common disorders. Each chapter offers learning objectives to aid readers in recognizing important points and connecting the basic radiology concepts. The sixth edition is thoroughly updated. The editors and authors introduce the approach to SAFE radiology, explaining the concepts of S-safety in all modalities, A-appropriateness of imaging ordering, F-interpreting films and E-acting expeditiously on significant findings and executing the recommendation of the imaging findings. Easy to learn and easy to remember, SAFE reminds all health care professionals that safety and appropriateness should precede any imaging testing and that all results should be applied expeditiously and thoughtfully.

This text provides a comprehensive review of the assessment and management of pediatric voice and swallow disorders from the perspectives of both the pediatric laryngologist as well as the speech-language pathologist whose collaboration is critical to effective clinical care. All chapters are written by experts in dual fields and formatted to present a straightforward approach to diagnosing and managing each disorder, including descriptions of relevant operative interventions. Multiple intraoperative photographs and illustrations depicting how to perform each surgical procedure are also included. Multidisciplinary Management of Pediatric Voice and Swallowing Disorders will serve as a useful step-by-step guide and resource not only for otolaryngologists and speech-language pathologists, but all members of the pediatric aerodigestive team and other providers caring for children affected by voice and swallowing disorders.

This fully updated second edition is a definitive guide to imaging and differential diagnosis for pediatric pulmonary diseases and disorders. This edition is fully updated to include coverage of the latest imaging and diagnostic techniques, modalities, and best practices. Beginning with clinical algorithms, chapters provide a framework for clinical diagnosis. This image-based text presents a comprehensive, multi-modality approach, with an emphasis on plain film and cross-sectional imaging. The imaging sections, including a new chapter on pediatric thoracic MRI, are correlated with pathology and clinical findings to help readers learn what the modality of choice can enable them to see. This information and guidance is applied directly to diseases and disorders seen in everyday practice, including pleural effusion, focal lung disorders, pulmonary hypertension, cystic fibrosis, and asthma, as well as a new chapter on pediatric pulmonary embolism. In addition, a new chapter on thegenetics of pediatric lung disorders has been added. This essential guide gives pediatric pulmonologists and radiologists the information to identify the differentials by symptom complex, accordingly determine what test would be effective, how to proceed, and to essentially provide the best care for their patients.

This book provides a guide to the anatomy and the surgical techniques required in thoracic and cardiothoracic surgery. It discusses the advantages and disadvantages of certain surgical procedures in relation to the lymphatic system, thyroid gland, chest wall and parathyroid glands, as well as pulmonary endarterectomy. Further, it addresses intraoperative and postoperative complications, and explores newer fields like microthymectomy, microlobectomy, and pain management for thoracic surgery patients. Providing an update on the latest advances in thoracic surgery, it appeals to general, thoracic, cardiothoracic, and cardiovascular surgeons. It also offers trainees insights into the foundation of the techniques and the relevant anatomy.

This updated volume covers the basic principles and practice of dialysis access management. To cover the latest trends and evidence from clinical trials, new chapters on the management of cephalic arch stenosis and swing zone stenosis, the role of drug eluting balloon in dialysis access interventions, the management of central vein stenosis, endovascular creation of AVF, and the management of steal syndrome have been included. Dialysis Access Management gives readers a step-by-step guide to endovascular interventions with special emphasis on the principles and rationale behind these approaches. This book is an essential text for residents, fellows, and physicians who are learning or practicing in dialysis, especially in the fields of nephrology, radiology, surgery, and vascular medicine.

Cystic fibrosis is a disease that affects the entire body. It tends to be thought of as primarily a pulmonary disease since pulmonary decline is the main factor in early mortality. Because of the multi-system nature of the disease, a better understanding of cystic fibrosis expands the family physician's understanding of subjects ranging from genetics to pulmonary function to nutrition to colon transport to hydration to electrolyte management. The primary care philosophy is unique in that it always considers how a narrow problem can affect an individual globally. Cystic Fibrosis care can often feel fractured to patients as they are sent to multiple specialists to deal with problems outside of the comfort level of a prior or current specialist. With a broad medical philosophy, care is more inclusive as clinicians can manage topics such as diabetes and preventive care without multiple referrals and additional appointments. Family physicians are well-positioned and well-qualified to competently meet many of the care needs of those with cystic fibrosis. This book is edited by a family medicine physician who has specialist level experience with the disease. It opens with a background on cystic fibrosis foundations and centers to familiarize the reader. The next chapter gives a basic overview of the disease. Each of the subsequent chapters provide a comprehensive look at how cystic fibrosis affects other areas of the body that the primary care physician should be familiar with. Major components of cystic fibrosis such as physiology, spirometry, inflammation, airway clearance, chronic infection, cystic fibrosis related diabetes and pancreatic insufficiency, among others, are thoroughly explained. Written by experts in the field, Cystic Fibrosis in Primary Care appeals to all family physicians as well as specialists, residents, medical students physician assistants and nurse practitioners alike.

This book provides a comprehensive overview of deep learning (DL) in medical and healthcare applications, including the fundamentals and current advances in medical image analysis, state-of-the-art DL methods for medical image analysis and real-world, deep learning-based clinical computer-aided diagnosis systems. Deep learning (DL) is one of the key techniques of artificial intelligence (AI) and today plays an important role in numerous academic and industrial areas. DL involves using a neural network with many layers (deep structure) between input and output, and its main advantage of is that it can automatically learn data-driven, highly representative and hierarchical features and perform feature extraction and classification on one network. DL can be used to model or simulate an intelligent system or process using annotated training data. Recently, DL has become widely used in medical applications, such as anatomic modelling, tumour detection, disease classification, computer-aided diagnosis and surgical planning. This book is intended for computer science and engineering students and researchers, medical professionals and anyone interested using DL techniques.

The book covers basic theories, basic knowledge and basic skills on clinical diagnosis, basic requirements for doctors'ethical conduct, clinical reasoning and documentation of medical records during the process of making a diagnosis. It consists of six parts, including ‘Symptoms', ‘History Taking', ‘Physical Examination', ‘Supplementary Examination', ‘Common Clinical Diagnosis Techniques', and ‘Diagnostic Process and Clinical Reasoning'. A vocabulary index is included for easy reference at the end of the book. This book is compiled by authors of 14 Chinese medical schools and universities, whose years of experience in clinical diagnostics, rich overseas learning and working experiences. This book is included in the first round of English textbooks series for clinical medicine major of China's higher medical colleges; and is among'13th Five-Year'planning textbooks of National Health Commission of the People's Republic of China. It is also an ideal textbook for MBBS(Bachelor of Medicine and Bachelor of Surgery) student It is a co-publication book with People's Medical Publishing House (PMPH). The ISBN of PMPH version in China is 978-7-117-23852-6.

This textbook explores the fundamental qualitative and quantitative aspects of human physiology. It approaches biological and physiological processes and phenomena from a quantitative perspective, revealing how physiological problems can be mathematically formulated starting from simple laws of physics. The book addresses a broad range of topics, including: the statics and dynamics of circulation; muscle and sarcomere force-length and force-velocity relations, together with their mechanisms and functional consequences; subdivisions and meaning of the heat produced by muscle; locomotion, statics and dynamics of respiration; diffusion of gases and acid base equilibrium; phonation; general functions of the kidney and of the different sections of the nephron; changes in clearance with a substance's plasmatic concentration; pH regulation and the kidney; Donnan's equilibrium and its consequences; and the Nernst equation. The book offers the ideal learning resource for students ofhuman physiology courses in medicine and biomedicine, as well as biomedical engineering and biophysics graduate students. An elementary grasp of mathematics and physics is sufficient to understand the content.

With the aid of a series of instructive case studies, this book presents the characteristic high-resolution computed tomography (HRCT) findings seen in the group of disorders referred to as interstitial lung disease. The first, introductory part of the book explains the role of the multidisciplinary team in diagnosis and differential diagnosis and discusses basic pulmonary differential diagnosis, radiologic anatomy, and HRCT patterns. The second part is organized according to the four dominant types of HRCT pattern encountered in interstitial lung disease: low attenuation, linear opacities, nodular, and high attenuation. Within this classification, each disorder is introduced using a specific case, with detailed information on patient history, course of the illness, and laboratory and pulmonary function tests. HRCT findings are then presented, together with reflections of the multidisciplinary team, comprising a radiologist, a pulmonologist, and a pathologist. At the end of each case,comments are made on differential diagnosis, highlighting the role of HRCT. The book will be of high value for radiologists and pulmonologists at all levels of experience.

This book presents different patient-oriented perspectives from surgeons, economic evaluation and management researchers, and business companies active in the healthcare sector, striking a balance between the appropriateness/effectiveness of treatment and efficiency/cost. It does not include technical surgical details, but instead provides the necessary knowledge regarding different groups of patients to help economic and management researchers make accurate evaluations. Although partially based on the specific case of abdominal wall surgery in the Italian health system, the book defines a model that can, with the necessary adaptations, be applied in other national contexts. It also analyzes different reimbursement systems and methods of data collection. This approach supports the evolution from evidence-based medicine (EBM) to the future of real-world data (big data analysis). Further, it highlights the critical issue of “silos” reimbursement, which is the pillar ofDRG, and proposes methodology to evaluate the direct and indirect benefit and costs of surgery (for example quality of care, costs incurred in cases of surgical complications due to the use of inappropriate, low-cost material or due to surgical procedure. It is a valuable resource for clinicians, surgeons, policymakers and managers in the field.

The second edition of this book brings together the knowledge, skills and attitudes of specialists in both respiratory and palliative medicine to focus on the palliative care of patients with respiratory diseases. It deals not only with end of life care but also with symptom control and supportive care to improve the quality of life of those living their lives with advanced progressive lung disease. Integrated Palliative Care of Respiratory Disease builds on the previous edition introducing new models of care for patients with advanced lung disease. These models emphasize the introduction of palliative and supportive care at an earlier stage in the disease, and running disease-modifying and palliative treatments in parallel. There is a new chapter on the role of palliative care in lung transplantation'. The book highlights significant new research into key respiratory diseases and some on-going controversies about issues such as best models of care for different diseases and advance care planning. This book is an invaluable reference for doctors, trainees and clinical nurse specialists in respiratory and palliative medicine, and is of interest to anyone who wishes to gain a better understanding of the complex nature of palliative care in respiratory disease.

The 25th volume of this highly successful series covers a range of interesting topics, including biological therapy in inflammatory bowel disease, recent surgical approaches in rectal cancer, tumor markers in HPB and GI malignancies, bridging therapy for hepatocellular carcinoma, adjuncts to liver resection, IgG-related HPB diseases, ERCP-induced perforations and superior mesenteric artery syndrome. As in the previous volumes, the chapter on advances in GI surgery reviews the important new developments in the field. The GI Surgery Annual 25th Volume provides up-to-date information on current hot topics.

The food industry is now entering a transition age, as scientific advancements and technological innovations restructure what people eat and how people think about food. Food Tech Transitions provides a critical analysis of food technology and its impact, including the disruption potential of production and consumption logic, nutrition patterns, agronomic practices, and the human, environmental and animal ethics that are associated with technological change.This book is designed to integrate knowledge about food technology within the social sciences and a wider social perspective. Starting with an overview of the technological and ecological changes currently shaping the food industry and society at large, authors tackle recent advancements in food processing, preserving, distributing and meal creation through the lens of wider social issues.Section 1 provides an overview of the changes in the industry and its (often uneven) advancements, as well as related social, ecological and political issues. Section 2 addresses the more subtle sociological questions around production and consumption through case-studies. Section 3 embraces a more agronomic and wider agricultural perspective, questioning the suitability and adaptation of existing plants and resources for novel food technologies. Section 4 investigates nutrition-related issues stemming from altered dietary patterns. Finally, Section 5 addresses ethical questions related to food technology and the sustainability imperative in its tripartite form (social, environmental and economic).The editors have designed the book as an interdisciplinary tool for academics and policymakers working in the food sciences and agronomy, as well as other related disciplines.

This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients. Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.

This book describes the developments and improvements in electroencephalography (EEG). In recent years, digital technology has replaced analog equipments, and it is now possible to easily record and store EEG tracings and to quickly recall previously acquired material for subsequent analysis. In addition, not only static figures, but also electronic supplementary materials can be included in books, enabling EEGs to be viewed in real-time.In clinical practice, EEG still represents the most important functional examination in the study CNS development and its anatomical and physiological integrity throughout life. In the pathological context, EEG provides indispensable diagnostic information for classification of epileptic syndromes, and it is also valuable in all the other CNS diseases (infectious, cerebrovascular, neurodegenerative, etc).Furthermore, monitoring EEG can be widely used in emergency settings, such as emergency departments or intensive care units. In comatose patients, EEG provides information regarding prognosis and evaluation of the sedative effect of anesthetic drugs.Written by a group of leading national and international experts, it offers a substantial, yet practical, EEG compendium, which serves as a reference resource for physicians and neurodiagnostic technologists as well as physicians-in-training, researchers, practicing electroencephalographers and students.

This book weaves all of these factors together to engage in and promote medical, biomedical and psychosocial interventions, including lifestyle changes, for healthier aging outcomes. The text begins with an introduction to age-related changes that increase in disease and disability commonly associated with old age. Written by experts in healthy aging, the text approaches the principles of disease and disability prevention via specific health issues. Each chapter highlights the challenge of not just increasing life expectancy but also deceasing disease burden and disability in old age. The text then shifts into the whole-person implications for clinicians working with older patients, including the social and cultural considerations that are necessary for improved outcomes as Baby Boomers age and healthcare systems worldwide adjust. Healthy Aging is an important resource for those working with older patients, including geriatricians, family medicine physicians, nurses, gerontologists, students, public health administrators, and all other medical professionals.

An introductory text that transitions into a moderately advanced, case-based analysis of neurologic disorders and diseases, this book emphasizes how to simplify the process of making a neurologic diagnosis. Medical students and residents are often intimidated by a deluge of data, perception of anatomic complexity, extensive differential diagnoses, and often have no organized structure to follow. Diagnostic methods of general medicine are not applicable. Indeed, neurology is a unique specialty since it requires the intermediary step of an anatomic diagnosis prior to proffering a differential diagnosis. Yet the required knowledge of neuroanatomy need not be profound for the student or resident who will not specialize in neurology or neurosurgery. The Neurologic Diagnosis: A Practical Bedside Approach, 2nd Edition is primarily directed to neurology and neurosurgery residents but it will be useful for medical and family practice residents who will discover that a great percentage of their patients have neurologic symptoms. A one-month neurology rotation out of four years of medical school is not sufficient to make a cogent neurologic diagnosis. The aim of this concise, practical book -- which includes an in-depth video of how to perform a neurologic examination -- is to facilitate the process of establishing a neuroanatomic diagnosis followed by a rigorous analysis of symptoms and signs to reach a well-thought out differential diagnosis. Focused and succinct, this book is an invaluable resource for making a lucid neurologic diagnosis.

This book is an introduction to chest radiology, specifically designed for the needs of first-year residents. On the first rotation in chest imaging, radiology residents are asked to learn significant amounts of information at a fast and unrelenting pace. However, most current books are densely written and contain far more material than residents need to know. Moreover, the number, variety, and quality of images is often limited. What Radiology Residents Need to Know: Chest Radiology answers these needs by presenting the important information in bullet fashion, divided into convenient sub-units, such as “clinical information,” “imaging findings,” and “management.” In most cases, an individual pathological condition can be presented in one page or less. This book covers such topics as volume loss, pneumonia, pulmonary edema, inhalation diseases, and pulmonary, mediastinal, and pleural tumor imaging. In addition, it contains tips on approaching andinterpreting chest radiographs and CT based on decades of practical experience and teaching residents at the work station. With liberal use of illustrations in the text and an online bank of many more high-quality images, this book gives readers a comprehensive library of chest imaging scans and serves as an ideal guide for radiology residents.

This introduces the history, development and current status of uniportal VATS by pioneers and authorities of this technique. The highly illustrated content in the chapters enhances readers to rapidly understand the techniques of uniportal VAT. The use of video clips adds value to the learning experience and applicability of the techniques. The contents will be of great interest to thoracic surgeons who are already practicing video-assisted thoracic surgery, as well as those who are starting training. It will also serve as authoritative reference text for doctors, students and allied health professionals who would like to learn more about the new technique of uniportal VATS.

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of'hot topics'. The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.

Allergy and Asthma: The Basics to Best Practices is intended to serve as a single comprehensive reference covering all needed knowledge of allergic diseases. Allergy is a unique and distinctive area of medicine wherein learning the fundamentals requires gathering information from various different disciplines. Allergic diseases affect various organ systems and the practice of a wide range of physicians from otolaryngologists, and pulmonologists, to gastroenterologists, dermatologists, and ophthalmologists. Clinicians and trainees alike will benefit from a resource that introduces the basic concepts, as well as providing comprehensive, consistently up-to-date instruction on intermediate and advanced conditions, research, and treatment strategies. The book is divided into nine sections and is written by some of the foremost experts in the field. Allergy and Asthma opens with an introduction which covers the epidemiology of allergicdiseases, fundamentals of allergy and immunology, and a thorough grounding of different types of allergens. Early sections address allergic upper airway diseases, allergic skin diseases, and asthma in detail, using a structured, consistent format from chapter to chapter to provide continuity and ease of reference. Later sections thoroughly cover various food allergies, insect allergies, drug allergy, anaphylaxis, and utilize ample tables and illustrations to provide additional learning tools for the reader. This major reference not only provides basic knowledge on diagnosing and treating allergies, but moves beyond these basics to emphasize using a systematic approach to working up and treating a patient. A variety of techniques used in diagnosing asthma and allergy will be examined, of which include prick skin tests, in-vitro testing, patch testing and non-conventional allergy tests. Concluding this book are sections dedicated to management, therapeutic strategies of allergy and asthma, with a look to future research directions for this unique field.Physicians and residents in allergy and immunology, pulmonology, otolaryngology, gastroenterology, dermatology, ophthalmology and other specialties will find the work of value in enhancing their practice and studies. Researchers in a range of areas especially immunology and food science will also find this text to be a compelling and reliable resource.

The six-volume set LNCS 11764, 11765, 11766, 11767, 11768, and 11769 constitutes the refereed proceedings of the 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2019, held in Shenzhen, China, in October 2019. The 539 revised full papers presented were carefully reviewed and selected from 1730 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: optical imaging; endoscopy; microscopy.Part II: image segmentation; image registration; cardiovascular imaging; growth, development, atrophy and progression.Part III: neuroimage reconstruction and synthesis; neuroimage segmentation; diffusion weighted magnetic resonance imaging; functional neuroimaging (fMRI); miscellaneous neuroimaging.Part IV: shape; prediction; detection and localization; machine learning; computer-aided diagnosis; image reconstruction and synthesis.Part V: computer assisted interventions; MIC meets CAI. Part VI: computed tomography; X-ray imaging.

This book provides, for the first time, a unified approach to the application of MRI in radiotherapy that incorporates both a physics and a clinical perspective. Readers will find detailed information and guidance on the role of MRI in all aspects of treatment, from dose planning, with or without CT, through to response assessment. Extensive coverage is devoted to the latest technological developments and emerging options. These include hybrid MRI treatment systems, such as MRI-Linac and proton-guided systems, which are ushering in an era of real-time MRI guidance. The past decade has witnessed an unprecedented rise in the use of MRI in the radiation treatment of cancer. The development of highly conformal dose delivery techniques has led to a growing need to harness advanced imaging for patient treatment. With its flexible soft tissue contrast and ability to acquire functional information, MRI offers advantages at all stages of treatment. In documenting the state of the art in thefield, this book will be of value to a wide range of professionals. The authors are international experts drawn from the scientific committee of the 2017 MR in RT symposium and the faculty of the ESTRO teaching course on imaging for physicists.

This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implicationsfor radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.

This book presents a clear and concise summary of the clinical tenets of lung transplantation with an update on recent developments in the field. It examines the operational principles which underpin successful lung transplantation and shows how an evidenced based approach combined with wisdom borne of experience leads to better outcomes in day-to-day management. Focused on simplicity and elegance of style with ample visual images, this book provides a unique overview of trends and strategies for the best outcomes in lung transplantation. Approachable and easily digested, this book will be a go-to resource for professionals seeking a succinct and well-illustrated guide to this growing area of surgical transplantation.

The fourth edition of this well-received book offers a comprehensive update on recent developments and trends in the clinical and scientific applications of multislice computed tomography. Following an initial section on the most significant current technical aspects and issues, detailed information is provided on a comprehensive range of diagnostic applications. Imaging of the head and neck, the cardiovascular system, the abdomen, and the lungs is covered in depth, describing the application of multislice CT in a variety of tumors and other pathologies. Emerging fields such as pediatric imaging and CT-guided interventions are fully addressed, and emergency CT is also covered. Radiation exposure, dual-energy imaging, contrast enhancement, image postprocessing, CT perfusion imaging, and CT angiography all receive close attention. The new edition has been comprehensively revised and complemented by contributions from highly experienced and well-known authors who offer diverse perspectives, highlighting the possibilities offered by the most modern multidetector CT systems. This book will be particularly useful for general users of CT systems who wish to upgrade and enhance not only their machines but also their knowledge.

This revised and updated book provides a simplified approach to interpreting most diagnostic tests in the field of respiratory medicine. Easy to understand and practical, it contains more than 125 illustrated diagrams and over 50 tables with essential information that summarize the various diagnostic tests and interpretative approaches in a simple and understandable fashion. Of special note are chapters on exercise testing and diagnostic tests for sleep disorders, the latter a new and emerging field. This new edition contains revised information based on the newest ATS guidelines.Pulmonary Function Tests in Clinical Practice Second Edition assists residents and fellows in internal medicine, pulmonology, allergology and critical care by explaining the key information obtained from lung volume measurement and increases understanding of pulmonary function tests within the modern diagnostic armamentarium.

Renal cell carcinoma (RCC) is the most common primary malignancy of the kidney, with an estimated 64,000 new cases diagnosed each year in the United States. Worldwide, this figure approaches 270,000 annual incident cases. At the time of initial presentation, 80% of patients with RCC will be diagnosed with a tumor localized the kidney. The majority of these lesions will be small (i.e. ≤4 cm) and potentially curable with either partial or radical nephrectomy. In recent decades, the rate of incidentally detected small renal tumors has risen substantially due the increasing use of cross-sectional imaging performed across the field of medicine. This rise in the incident number of localized renal tumors has unfortunately not resulted in a corresponding decrease in cases of metastatic RCC. This observation has led to our understanding that a significant proportion of incidentally detected renal tumors are of low malignant potential and may be safely managed with alternatives to surgery such active surveillance and thermo ablation. The use of these less invasive management approaches, however, must be balanced by the reality that upon spreading beyond the confines of the kidney, RCC is almost always incurable. Thus, when selecting a management strategy for a given patient, one must employ a risk-adapted approach that includes knowledge of a tumor's histology and metastatic potential. In each patient, the goal of management should be to minimize the risk of progression to metastatic disease while preserving renal function and minimizing morbidity.This text provides a contemporary review of the diagnosis and surgical management of RCC. It opens with chapters on the pathology, radiology, and genetics of RCC. It then covers the risk stratification of renal tumors utilizing renal mass biopsy as well as non-invasive novel imaging-based scoring systems. Next, the surgical management of small and locally advanced renal tumors as well as the role of surgeryin cases of metastatic RCC is reviewed. In addition, alternative approaches to surgery including active surveillance and ablative techniques are reviewed. Other chapters detail the emerging role of neoadjuvant and adjuvant systemic therapy in patients who are at high risk of progression to metastatic disease. Finally, the text covers the post-operative surveillance of patients with RCC as well as a summary of contemporary guidelines on the management of this disease. Diagnosis and Surgical Management of Renal Cell Carcinoma will serve as a comprehensive resource for physicians and researchers interested in RCC. All chapters will be written by experts in the field and will include the most up to date scientific and clinical information.

This book constitutes the proceedings of the 26th International Conference on Information Processing in Medical Imaging, IPMI 2019, held at the Hong Kong University of Science and Technology, Hong Kong, China, in June 2019. The 69 full papers presented in this volume were carefully reviewed and selected from 229 submissions. They were organized in topical sections on deep learning and segmentation; classification and inference; reconstruction; disease modeling; shape, registration; learning motion; functional imaging; and white matter imaging. The book also includes a number of post papers.

Updated and expanded, this comprehensive new edition captures the considerable evolution in the anesthetic management of patients requiring anesthesia for non-cardiac intrathoracic diagnostic and therapeutic procedures. Major advances addressed include the expanded role of ultrasound beyond trans-esophageal echocardiography, the role of extra-corporeal membrane oxygenation in thoracic anesthesia, and postoperative pain management for thoracic surgery. Chapters are authored by prominent anesthesiologists and feature cases commonly encountered in clinical practice. Authoritative and the leading text in the field, this book will serve as an indispensible guide to practitioners of thoracic anesthesia at all levels.