1. Comorbidity in Disease-Free Survivors of Cervical Cancer Compared with the General Female Population
- Author
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Young Ho Yun, Duk-Soo Bae, Chi Heum Cho, Yong Chul Kwon, Jong Min Lee, Chong Taik Park, Sang Yoon Park, Joo-Hyun Nam, Sang Min Park, and Dong Wook Shin
- Subjects
Cancer Research ,medicine.medical_specialty ,Population ,MEDLINE ,Uterine Cervical Neoplasms ,Comorbidity ,Disease-Free Survival ,Quality of life ,Risk Factors ,Sickness Impact Profile ,Surveys and Questionnaires ,Internal medicine ,medicine ,Humans ,Survivors ,education ,Female population ,Gynecology ,Cervical cancer ,education.field_of_study ,business.industry ,Case-control study ,Cancer ,General Medicine ,Middle Aged ,medicine.disease ,Oncology ,Case-Control Studies ,Quality of Life ,Female ,business - Abstract
Objectives: We aimed to investigate the prevalence of comorbidities in cervical cancer survivors compared with the general population and to identify risk factors and impact on their quality of life (QoL). Methods: 860 female cervical cancer survivors enrolled at six tertiary hospitals and 994 women from the general population were surveyed on current comorbidities and QoL (EORTC QLQ-C30 and QLQ-CX24). Results: Compared with the general female population, the cervical cancer survivors reported higher prevalence of comorbidities (0.93 ± 2.91 vs. 0.37 ± 0.67, p < 0.01), significantly more heart disease (adjusted odds ratio (aOR), 2.64; 95% confidence interval (CI), 1.38–5.07), liver disease (aOR, 3.29; 95% CI, 1.54–7.02), hypertension (aOR, 1.72; 95% CI, 1.30–2.27), gastrointestinal disease (aOR, 1.79; 95% CI, 1.37–2.33) and musculoskeletal disease (aOR, 1.94; 95% CI, 1.45–2.59). Heart and renal disease significantly influenced QoL in many subscales. Patients with diabetes or cerebrovascular disease had an increased likelihood of sexual problems. Conclusions: The cervical cancer survivors had more comorbidities than the general population, and that in turn affected their QoL. Vigilant follow-up of comorbidities should be incorporated into in the care of cancer survivors.
- Published
- 2008