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Comorbidity in Disease-Free Survivors of Cervical Cancer Compared with the General Female Population
- Source :
- Oncology. 74:207-215
- Publication Year :
- 2008
- Publisher :
- S. Karger AG, 2008.
-
Abstract
- Objectives: We aimed to investigate the prevalence of comorbidities in cervical cancer survivors compared with the general population and to identify risk factors and impact on their quality of life (QoL). Methods: 860 female cervical cancer survivors enrolled at six tertiary hospitals and 994 women from the general population were surveyed on current comorbidities and QoL (EORTC QLQ-C30 and QLQ-CX24). Results: Compared with the general female population, the cervical cancer survivors reported higher prevalence of comorbidities (0.93 ± 2.91 vs. 0.37 ± 0.67, p < 0.01), significantly more heart disease (adjusted odds ratio (aOR), 2.64; 95% confidence interval (CI), 1.38–5.07), liver disease (aOR, 3.29; 95% CI, 1.54–7.02), hypertension (aOR, 1.72; 95% CI, 1.30–2.27), gastrointestinal disease (aOR, 1.79; 95% CI, 1.37–2.33) and musculoskeletal disease (aOR, 1.94; 95% CI, 1.45–2.59). Heart and renal disease significantly influenced QoL in many subscales. Patients with diabetes or cerebrovascular disease had an increased likelihood of sexual problems. Conclusions: The cervical cancer survivors had more comorbidities than the general population, and that in turn affected their QoL. Vigilant follow-up of comorbidities should be incorporated into in the care of cancer survivors.
- Subjects :
- Cancer Research
medicine.medical_specialty
Population
MEDLINE
Uterine Cervical Neoplasms
Comorbidity
Disease-Free Survival
Quality of life
Risk Factors
Sickness Impact Profile
Surveys and Questionnaires
Internal medicine
medicine
Humans
Survivors
education
Female population
Gynecology
Cervical cancer
education.field_of_study
business.industry
Case-control study
Cancer
General Medicine
Middle Aged
medicine.disease
Oncology
Case-Control Studies
Quality of Life
Female
business
Subjects
Details
- ISSN :
- 14230232 and 00302414
- Volume :
- 74
- Database :
- OpenAIRE
- Journal :
- Oncology
- Accession number :
- edsair.doi.dedup.....a4f9a6fb5643bf33bccf88ba064eb4cb