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A study conducted by the University of Verona in Italy focused on obtaining stem-like cells from gubernaculum testis biopsies of pediatric patients with cryptorchidism, a condition where one or both testicles fail to descend into the scrotum. The research aimed to explore the potential of these cells to differentiate into testicular functioning cells for fertility preservation. The results showed that the obtainment of stem-like cell aggregates was not dependent on the age of the patients or the damage suffered by the testis, suggesting a new potential approach to support fertility potential in older patients. The study has been peer-reviewed and offers promising implications for future research in this area. [Extracted from the article]

A study conducted by the University of Verona in Italy focused on developing and validating the Arabic children's strong communication scale (ACSCS) to assess communication skills in Arabic-speaking children. The scale, based on the children's communication checklist-2 (CCC-2), consists of 22 items targeting language proficiency, social communication, and behavioral aspects. The research confirmed the ACSCS as a valid and reliable tool for measuring communication strengths in Arabic-speaking children, with implications for educational and clinical settings. The study highlights the importance of culturally sensitive assessment tools to support the communication development of diverse populations. [Extracted from the article]

A recent study conducted in Verona, Italy examined the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in children and adolescents with type 1 diabetes (T1D). The study found that MASLD is a common condition in this population, with a prevalence of 27.5%. The researchers identified several factors that were independently associated with the presence of MASLD, including long-term glycemic control, blood pressure, and LDL cholesterol levels. These findings highlight the importance of monitoring and managing these risk factors in individuals with T1D to prevent the development of MASLD and its associated complications. [Extracted from the article]

A recent study conducted by researchers at the University and Hospital Trust of Verona in Italy provides new insights into the neoplastic progression of pancreatic neuroendocrine neoplasms (PanNENs). PanNENs are a diverse group of tumors that can be classified into well-differentiated pancreatic neuroendocrine tumors (PanNETs) and poorly differentiated pancreatic neuroendocrine carcinomas (PanNECs). The study found that PanNETs can progress to more aggressive tumors (G3) due to specific genetic mutations, while PanNECs have distinct molecular features similar to pancreatic ductal adenocarcinoma. The researchers suggest that understanding these distinctions could lead to improved precision oncology for patients with PanNENs. [Extracted from the article]

A recent study conducted at the University of Verona in Italy has developed a new control algorithm for a 7-DOF redundant robotic arm used in minimally invasive surgery. The algorithm addresses the challenges of ensuring safety with software-based remote center of motion (RCM) constraints. By formulating a quadratic optimization problem under linear constraints, the algorithm guarantees the performance, safety, and stability of the robotic arm, even in the presence of communication delays. Experimental validation demonstrated the effectiveness and accuracy of the algorithm in executing surgical tasks. The implementation of the RCM constraint successfully ensures patient safety and optimizes the manipulation capabilities of the robotic arm. [Extracted from the article]

A recent report from the University of Verona in Italy explores the role of therapeutic alliance and biobehavioural synchrony in musculoskeletal care. The study emphasizes the importance of collaborative patient-clinician interactions and the alignment of personal beliefs in fostering positive treatment outcomes. The research conducted semi-structured interviews with manual therapists and identified three main categories: creating a meaningful dialogue, promoting active patient participation, and synchronization. The study concludes that further research is needed to explore these elements and their impact. [Extracted from the article]

A recent study conducted at the University of Verona in Italy examined the effectiveness of different treatment regimens for mantle cell lymphoma (MCL). The researchers found that bendamustine-rituximab (BR) followed by rituximab maintenance (R) was an effective induction regimen, particularly for older patients. The study also found that the addition of bortezomib or lenalidomide to the treatment did not improve progression-free survival and was associated with increased risks of neutropenia and other adverse events. This research provides valuable insights into the optimal treatment options for MCL patients. [Extracted from the article]

A recent study conducted in Verona, Italy, evaluated the acute toxicity of stereotactic body radiotherapy (SBRT) in patients with oligometastatic cancer. The study, called OligoCare, is a prospective, registry-based, observational study that aims to gather real-world data on patients with oligometastases treated with SBRT. The analysis included patients with non-small cell lung cancer, breast cancer, colorectal cancer, and prostate cancer. The study found that acute toxicity within 6 months was low, indicating the safety of SBRT in treating oligometastases. OligoCare is the largest prospective registry cohort on oligometastatic disease. [Extracted from the article]

A study conducted by researchers at the University of Verona in Italy explores the use of liquid chromatography-mass spectrometry (LC-MS) in analyzing chemical contaminants in food. The study reviews the methodologies used for determining veterinary drugs and pesticides in food and discusses the strengths and limitations of LC-MS screening methods. The research provides prospective directions for advancing LC-MS methodologies in this field. The study has been peer-reviewed and is available for further information. [Extracted from the article]

A recent study conducted by the University of Verona in Italy focuses on the classification and management of black stains (BS) in children's teeth. BS are acquired oral pathology characterized by black spots on the lingual and vestibular surfaces of deciduous and permanent teeth. The study highlights the challenge of treating BS due to their high recurrence rate and insufficient oral hygiene practices among children. The researchers propose a new classification and a flowchart to assist pediatric dentists in managing BS and preventing their recurrence. Although there is no universally effective clinical protocol for treating BS, this study aims to provide guidance in this area. [Extracted from the article]

A recent study conducted by the University of Verona in Italy compared the outcomes of one-stage Pelnac reconstruction and full thickness skin grafts for wound healing in the radial forearm and fibula donor sites. The study included 21 patients who underwent reconstruction surgery after oncological procedures. The results showed that patients treated with one-stage Pelnac reconstruction had good healing of the donor site with minor complications and comparable scar quality and limb function. The researchers concluded that while longer postoperative care is required, the long-term aesthetic and functional results are satisfactory compared to full thickness skin grafts. [Extracted from the article]

A recent study conducted by researchers at the University of Verona in Italy has focused on the evaluation of PD-L1 expression in melanoma samples. PD-L1 is a protein that plays a role in the immune checkpoint pathway and is targeted in immunotherapy treatments for melanoma. The researchers developed and validated a multiplex double staining protocol to identify PD-L1+ melanoma cells more clearly. Further studies are needed to assess the applicability and effectiveness of this technique. This research provides valuable insights into the challenges of PD-L1 evaluation in melanoma samples and contributes to the ongoing efforts to improve immunotherapy treatments for melanoma patients. [Extracted from the article]

A recent study conducted by the University of Verona in Italy explored the relationship between severe childhood trauma and eating disorder symptoms. The study found that individuals with severe childhood trauma had more severe eating disorder symptoms and higher scores on early maladaptive schemas related to emotional deprivation, defectiveness, failure, vulnerability, insufficient self-control, and negativity. These schemas were found to mediate the relationship between childhood trauma and eating disorder symptom severity. The study suggests that early maladaptive schemas should be considered in the treatment of individuals with eating disorders who have a history of trauma. [Extracted from the article]

A research report from the University of Verona in Italy discusses the case of a 7-year-old girl who presented with recurring headaches. The girl's family had a history of migraines and febrile seizures. During hyperventilation, the girl experienced episodes of acute aphasia, weakness, and headache. The researchers considered various possibilities, including an exaggerated physiological response, an epileptic nature of the events, and a migraine variant. The report highlights the importance of EEG findings in diagnosing this rare cerebrovascular disorder. [Extracted from the article]

A recent research study conducted at the University of Verona in Italy explored the combination of Acceptance and Commitment Therapy (ACT) and Adventure Therapy (AT) to maximize the effects of experiential exposure in therapeutic approaches. The study focused on a program called ESPRIMO 'Demons on the boat', which aimed to help young adults with multiple sclerosis adapt to their illness, chronicity, and disability. The program utilized a metaphor of navigation in the Mediterranean Sea to guide the therapeutic experience. The study found that the integration of ACT and AT elements in the program resulted in positive benefits for the participants on a bio-psycho-social level. The researchers concluded that the model is highly adaptable and can be used for a wide range of applications and vulnerable groups. [Extracted from the article]

A recent study from the University of Verona in Italy explores the challenges and unmet needs in the practical approach to hypereosinophilic syndromes (HES) and rare dysimmune conditions associated with hyper-eosinophilia. HES is a group of rare dis-immune conditions characterized by blood hyper-eosinophilia and eosinophilic related burden. The study highlights the difficulty in diagnosing and treating I-HES, the idiopathic subtype of HES, due to its heterogeneous clinical presentation and overlap with other conditions. The researchers propose an innovative multidisciplinary organizational model to address these challenges and improve patient care. [Extracted from the article]

A study conducted by the University of Verona in Italy explores the integration of various interventions in the management of chemotherapy-induced nausea and vomiting (CINV). Despite advancements in antiemetic drugs, CINV remains persistent in around 30% of adult patients, leading to complications and treatment discontinuation. The study highlights the benefits of supportive care interventions such as physical exercise, tailored nutritional counseling, psychological intervention, and acupuncture/acupressure in reducing the severity of CINV. The research aims to provide an update on current guidelines for CINV management and non-pharmacological interventions for alleviating CINV in cancer patients. [Extracted from the article]

The article from the University of Verona illuminates findings in neoplasms. Topics include the comprehensive characterization of intraductal oncocytic papillary neoplasm (IOPN) of the pancreas, the distinct clinicopathologic and molecular features of IOPN, and the identification of specific genomic fusions as promising biomarkers for diagnostic purposes.

A recent study conducted in Verona, Italy examined the impact of using one or two bars in the Nuss procedure, the primary treatment for pectus excavatum (PE), in young adults. The study included 182 patients who underwent the procedure and were categorized into one-bar or two-bar correction groups. The results showed that patients treated with two bars reported fewer psychological complaints post-surgery and had comparable clinical outcomes and quality of life to those with one bar. The study suggests potential advantages of the two-bar approach, but further research with larger sample sizes is needed to confirm these findings. [Extracted from the article]

A recent report from the University of Verona in Italy discusses the findings of a study on airborne diseases. The researchers developed a pollen modeling system to accurately predict pollen concentrations in the Veneto Region of Italy. They compared the predictions using different vegetation cover maps and found that using high-resolution data significantly improved the accuracy of predictions for certain types of pollen. The study highlights the importance of incorporating detailed vegetation maps into atmospheric dispersion models for more precise predictions of airborne pollen concentrations. [Extracted from the article]

A recent study conducted by researchers at the University of Verona in Italy has found that preserving the hyo-styloglossus unit (HSU) during glossectomy surgery can lead to positive functional outcomes for patients. Glossectomy is a surgical procedure used to remove tongue tumors, and the preservation of the HSU aims to maintain tongue function. The study involved six patients who underwent extended glossectomy Type B (EG Type B) with preservation of the HSU, and the results showed that five out of the six patients were alive and disease-free. The researchers concluded that preserving the HSU is important for successful swallowing rehabilitation. [Extracted from the article]

New research from the University of Verona in Italy highlights the increasing prevalence of adult food allergies. While anaphylaxis in adults is often attributed to drug reactions, foods are becoming a significant trigger, with a wide range of food triggers that differ from those in children. The study emphasizes the importance of considering unusual food triggers and potential co-factors in managing anaphylaxis in adults. Further research is needed to better understand adult food allergies, their triggers, and symptom severity. [Extracted from the article]

A study conducted at the University of Verona in Italy examined the factors that impact operating time during robot-assisted radical prostatectomy (RARP) for prostate cancer. The study found that high-volume surgeons (HVS) were able to decrease operating time independently of clinical and anatomical/perioperative factors. This information can be used to optimize waiting lists, teaching tasks, operative costs, and surgeon's volume. The study was published in Minerva Urology and Nephrology and has been peer-reviewed. [Extracted from the article]

A recent study conducted by researchers at the University of Verona in Italy explores the sensory aspects of Restless Legs Syndrome (RLS), a sleep-related movement disorder. The study aims to better understand the clinical and functional substrates of RLS, particularly its sensory symptoms and their neurophysiological and anatomical correlates. The research suggests that anomalies in sensorimotor integration and central sensitization may contribute to the sensory component of RLS. Additionally, neuroimaging data indicate the involvement of various brain areas and circuits, with the thalamus playing a significant role. The study concludes that a comprehensive approach is necessary to unravel the complex framework of RLS, considering brain connectivity, structural and functional abnormalities, molecular vulnerability, and neurotransmitter alterations. [Extracted from the article]

A recent study conducted at the University of Verona in Italy compared two sodium hyaluronate-based ophthalmical viscosurgical devices (OVDs) used during cataract surgery. The study found that the bacteria-derived FIDIAL PLUS OVD was as effective and safe as the animal-derived IAL (R)-F OVD. The research involved 50 patients with bilateral cataract, and the results showed no significant increase in intraocular pressure or adverse effects in either group. This study confirms the clinical value of the FIDIAL PLUS OVD. [Extracted from the article]

A recent study conducted by researchers at the University of Verona in Italy explored the neural substrates of social cognition deficits in newly diagnosed multiple sclerosis (MS) patients. The study found that MS patients exhibited impairments in facial emotion recognition and theory of mind compared to healthy controls. These deficits were present at the time of diagnosis and persisted throughout the disease course. The study also identified specific brain regions, such as the amygdala, caudate, and putamen, that played a significant role in these cognitive alterations. [Extracted from the article]

Researchers at the University of Verona in Italy have conducted a study on the reactions of US financial markets to press news from January 2019 to May 2020. Using unsupervised machine learning techniques, they developed indices to determine the content and uncertainty of news articles from The New York Times. The study found that two topic-specific uncertainty indices, related to COVID-19 news and trade war news, explained the majority of movements in the financial markets during this period. Additionally, the index related to the economy and the Federal Reserve was positively related to the financial markets, indicating its ability to capture the actions of the Federal Reserve during uncertain times. This research has been peer-reviewed and published in Advances in Data Analysis and Classification. [Extracted from the article]

A systematic review conducted by researchers at the University of Verona compared the effects of transdermal and oral hormone replacement therapy (HRT) in postmenopausal women. The review included 51 studies and found that transdermal and oral administration routes of HRT were similar in terms of improvements in bone mineral density, glucose metabolism, and lipid profile. However, the review identified a higher risk of venous thromboembolism (VTE) with oral administration. The researchers concluded that transdermal HRT may be safer than oral administration due to the lower risk of VTE. Further research is recommended to better understand the differences between the two administration routes. [Extracted from the article]

A recent study conducted by the University of Verona compared the knowledge, opinions, and clinical experiences of Czech, Slovak, and Italian neurologists regarding functional neurological disorder (FND). FND is a condition characterized by symptoms that are incompatible with other neurological disorders. The study found similarities between Czech, Slovak, and Italian neurologists in their preference for the term 'FND' and their belief that symptoms are due to abnormal functioning of the nervous system rather than mental illness. However, there were also differences, with Italian neurologists placing a greater emphasis on psychological factors and litigation, while Czech and Slovak neurologists were more likely to suggest physiotherapy and provide educational interventions for patients and their relatives. The study suggests that there are still significant gaps in understanding and common practices regarding the conceptualization, diagnosis, and treatment of FND among these neurologists. The researchers recommend promoting knowledge through postgraduate curricula and teaching courses to optimize patient management in various European countries. [Extracted from the article]

A study conducted by the University of Verona in Italy compared the outcomes of single-layer and double-layer renorrhaphy techniques during robot-assisted partial nephrectomy (RPN). The study analyzed data from 317 patients and found that both techniques had comparable perioperative and functional outcomes. There were no significant differences in terms of complications, blood loss, or postoperative renal function between the two groups. This research provides valuable insights for surgeons performing RPN procedures. [Extracted from the article]

A recent study conducted by researchers at the University of Verona in Italy explored the feasibility of an exercise program for women with breast cancer. The program allowed patients to choose from three exercise delivery modalities: personal training, home-based program, or group-based program. The study found that an exercise prescription based on a patient's preferred delivery modality was highly feasible and resulted in improvements in cardiorespiratory fitness, flexibility, body weight, and various quality-of-life domains. The research suggests that exercise can improve the quality of life and reduce side effects for breast cancer patients. [Extracted from the article]

A recent report from the University of Verona in Italy discusses the diagnosis, management, and therapeutic options for eosinophilic esophagitis (EoE). EoE is a chronic condition that can cause tissue damage and functional impairment, impacting quality of life. The report highlights recent advances in diagnostic work-up and treatment options, including the identification of three different endotypes of the disease and the development of specific drugs for EoE. The researchers emphasize the importance of a multidimensional approach involving gastroenterologists and allergist-immunologists to effectively manage EoE. [Extracted from the article]

A recent study conducted by the University of Verona in Italy examined the impact of trauma on asylum seekers and refugees who received a psychological intervention called Self-Help Plus (SH+), developed by the World Health Organization (WHO). The study found that individuals who had experienced multiple traumatic events had reduced benefits from SH+. Symptoms of post-traumatic stress disorder (PTSD) were found to mediate the relationship between trauma and psychological well-being and quality of life. The researchers suggest that healthcare professionals and researchers should consider the role of trauma and PTSD symptoms in the treatment of migrants and refugees and explore additional solutions for those exposed to multiple traumatic events. [Extracted from the article]

A recent study conducted at Verona University Hospital in Italy explores the use of coronary physiological assessment in managing patients with coronary artery disease. The study highlights the historical significance of this tool in determining the hemodynamic significance of artery lesions and its ability to investigate epicardial and microvascular circulation. The research emphasizes the importance of longitudinal assessment and post-percutaneous coronary intervention physiology reassessment in defining the best management and procedural planning. The study also discusses the potential applications and challenges of coronary physiology assessments, providing a historical overview and future perspectives. [Extracted from the article]

A recent report from the University of Verona in Italy highlights the role of occupational exposure to airborne pollutants in the development and exacerbation of chronic respiratory diseases. The study examined the association between occupational exposure and chronic bronchitis, asthma, and other respiratory conditions. The findings suggest that regular exposure to vapours, gases, dusts, and fumes is associated with a higher prevalence of chronic bronchitis, especially in individuals with asthma. The research emphasizes the importance of preventing workplace exposure to protect respiratory health, particularly for individuals with pre-existing respiratory conditions. [Extracted from the article]

A report from the University of Verona in Italy discusses the limitations of using ejection fraction (EF) as the main parameter for assessing ventricular performance in patients with left ventricular hypertrophy. The report highlights the potential of cardiac magnetic resonance feature-tracking (CMRFT) technology in providing a more comprehensive evaluation of myocardial function through strain measurements. However, the lack of established standards for image acquisition and interpretation, as well as variability introduced by different software vendors, has hindered the widespread adoption of CMR-FT in clinical practice. The research concludes that further evaluation is needed before CMR-FT can be effectively applied in clinical settings. [Extracted from the article]

New research conducted by the University of Verona focuses on the promotion of mental health in people living in low- and middle-income countries affected by humanitarian crises. The study found that psychosocial interventions may be helpful in promoting positive aspects of mental health, such as mental well-being, psychosocial functioning, coping, and quality of life. However, the evidence on the efficacy of these interventions is limited and inconclusive, with a scarcity of studies and a small number of participants analyzed. The researchers concluded that there is a significant gap between what is known and what still needs to be addressed in the research area of mental health promotion in humanitarian settings. [Extracted from the article]

A recent study conducted at the University of Verona in Italy explored the relationship between music exposure, maternal musicality, and vocabulary development in children with cochlear implants (CIs). The study found that children with CIs exhibited significant individual differences in vocabulary outcomes. The researchers discovered that music exposure and maternal musicality had positive effects on children's early receptive and expressive vocabulary. Despite low levels of music engagement and skills, the study suggests that involving children with CIs and their parents in music intervention programs may be beneficial. [Extracted from the article]

A study conducted by the University of Verona in Italy explores the management of metastatic gastric cancer. The research highlights the challenges faced by gastric cancer patients in Western countries, with a median overall survival of less than twelve months using standard chemotherapy. The study suggests that innovative treatments such as targeted therapy or immunotherapy have shown promise in improving prognosis. The research also emphasizes the need for a consensus on managing oligometastatic disease, with the definition of oligometastases restricted to specific sites. Surgical treatment of oligometastases should aim for curativity on the entire disease volume, including both the primary tumor and its metastases. [Extracted from the article]

A study conducted by Azienda Ospedaliera Universitaria Integrata Verona in Italy examined the complications associated with central venous catheters (CVCs) in pediatric patients with hematologic-oncologic diseases. The study found that CVC-related complications are a significant cause of morbidity in this patient population. The researchers identified various risk factors for complications, such as the type of CVC and age at insertion. The study emphasizes the importance of surveillance programs to identify risk factors and improve CVC management. [Extracted from the article]

A report from the University of Verona in Italy compares the safety profiles of different vaccination schedules for measles, mumps, rubella, and varicella (MMR and V) vaccines. The study analyzed data from the Veneto region's passive adverse event reporting system and found no safety signals supporting the evidence that MMRV and MMR-V vaccinations have a good safety profile. The reporting rate for serious events was slightly higher for the MMRV vaccine compared to the MMR-V vaccine. Further studies are needed to confirm the observation of a higher rate of serious events in males aged 0-2 years. [Extracted from the article]

A new report from the University of Verona in Italy discusses the search for potential inhibitors of DNA Polymerase, a drug target for the monkeypox virus (MPXV). The study screened 146 phytochemicals from Moringa oleifera and identified Riboflavin and Ellagic acid as potential inhibitors with high binding affinities. Molecular dynamics simulations and other analyses confirmed their stability and safety. Further experimental assays and clinical trials are needed to confirm their effectiveness against monkeypox. [Extracted from the article]

A recent report from the University of Verona in Italy discusses the potential use of gap junction modulators as antidotal agents for bupropion-induced cardiotoxicity. Bupropion, an antidepressant, has been associated with serious heart problems when misused. The researchers suggest that small-molecule drugs that enhance gap junction conductance could be effective in mitigating the cardiotoxic effects of bupropion. Further testing is needed to explore this potential treatment approach. [Extracted from the article]

A study conducted at the University of Verona in Italy provides insights into the characteristics of patients with benign prostatic hyperplasia (BPH) who visit outpatient offices. The study found that patients with known BPH were older and had higher rates of smoking, drinking, hypertension, obesity, diabetes, and cardiovascular diseases compared to newly diagnosed patients. Patients with known BPH also experienced more severe symptoms and concerns about their health and lost more time due to urinary problems. The research suggests that a healthy lifestyle and treatments including local anti-inflammatory agents may delay the worsening of symptoms and improve quality of life for BPH patients. [Extracted from the article]