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A recent study conducted by the Faculty of Veterinary Medicine University of Zagreb in Croatia focused on Leptospirosis in pet cats, a bacterial infection caused by pathogenic Leptospira spp. The research found that 18.52% of the tested cats had antibodies against Leptospira spp., with the Pomona serogroup being the most common. Cats with certain health conditions, such as immunocompromising conditions, were more likely to test positive for antibodies. The study highlights the importance of recognizing feline leptospirosis in veterinary care and understanding the potential role of pet cats as carriers of the infection. [Extracted from the article]

A recent study conducted at the University of Zagreb in Croatia explored self-recognition and self-perception of facial profiles in adolescents undergoing orthodontic treatment. The research found that there was no significant difference in self-recognition and self-perception among participants with straight, convex, and concave profiles. Females exhibited higher capability in self-perception compared to males. The study concluded that facial convexity does not influence self-recognition and self-perception of the soft-tissue profile. [Extracted from the article]

Researchers from the University of Rijeka in Croatia conducted a study on the impact of standard cross-linking (CXL) treatment on the corneal optical density-age relationship in keratoconus patients. The study found that CXL initially disrupts the relationship between corneal optical density and age, but this relationship is re-established by 12 months post-treatment. The change in corneal optical density following CXL is dependent on the pre-treatment value, not the patient's age. The findings were published in the Journal of Ophthalmology. [Extracted from the article]

A recent report from the University of Zagreb in Croatia discusses the development of a capillary electrophoresis method for determining Alpelisib (ALP) in pharmaceutical dosage forms, which is a novel treatment for metastatic breast cancer. The study highlights the need for reliable analytical methods for quality control of ALP and compares the performance of capillary electrophoresis to traditional liquid chromatography. The research suggests that capillary electrophoresis could be a greener and equally reliable alternative to liquid chromatography for analyzing ALP pharmaceutical dosage forms. [Extracted from the article]

A recent study from the University of Zagreb explores the importance of measuring Digital Business Models (DBMs) maturity, particularly for small and medium enterprises (SMEs). The research emphasizes the need for companies to adapt their business models in the digital age, highlighting the significance of user-generated content and user experience tracking for DBM maturity. The study, conducted on 162 SME companies from 42 countries, proposes a framework for measuring DBM maturity and identifies areas for improvement in implementing digital strategies. This peer-reviewed research contributes valuable insights for companies looking to enhance their digital business models. [Extracted from the article]

A recent study conducted at the Rudjer Boskovic Institute in Zagreb, Croatia, explored the impact of uncoated gold nanoparticles on model prokaryotic and eukaryotic lipid membranes. The research found that the presence of gold nanoparticles stabilized the gel phase of prokaryotic systems more than eukaryotic ones, suggesting that gold nanoparticles reduced the compactness of eukaryotic lipid bilayers. The study concluded that functionalizing gold nanoparticles could potentially reverse adverse effects when used as antimicrobials. This research has been peer-reviewed and published in Colloids and Surfaces B Biointerfaces. [Extracted from the article]

Researchers at the University of Zagreb in Croatia conducted a study on the solid-liquid phase behavior of novel mixtures involving the osmolyte sarcosine and chaotropes urea or guanidine hydrochloride. The study utilized differential scanning calorimetry and infrared spectroscopy to analyze the molar ratios of these components. The findings suggested that the stabilization of biomolecules by osmolytes may not solely rely on thermodynamics, indicating a need for further research in this area. This peer-reviewed research was supported by the Croatian Science Foundation and the European Union. [Extracted from the article]

A study conducted at the University of Zagreb in Croatia focused on using whole exome sequencing to identify gene variants in patients with childhood-onset systemic lupus erythematosus (cSLE). The research identified 17 novel and/or low-frequency gene variants in 7 patients, with one variant classified as pathogenic and two as likely pathogenic. The study concluded that whole exome sequencing is an important tool for diagnosing and researching cSLE, potentially leading to the discovery of new therapeutic targets. For more information, readers can refer to the article "Whole Exome Sequencing In Patients With Childhood-onset Systemic Lupus Erythematosus: Results From a Croatian National Study" published in the Scandinavian Journal of Immunology. [Extracted from the article]

A recent study conducted by the University of Zagreb in Croatia focused on predicting prolonged non-suicidal self-injury behavior and suicidal ideations in adolescents. The research found that factors such as adverse childhood experiences, neuroticism, family financial status, and self-concept variables played a role in determining whether adolescents continued with self-injurious behaviors. The study highlighted the importance of understanding and addressing mental health issues in adolescents to prevent and treat such behaviors effectively. [Extracted from the article]

A report from Children's Hospital Zagreb in Croatia discusses the challenges and advancements in diagnosing and managing pediatric blunt abdominal trauma. The research emphasizes the importance of standardized care for children with such injuries, highlighting a shift towards non-operative treatment for stable patients. The comprehensive review aims to systematize knowledge from pre-hospital to post-hospital care, providing insights for healthcare professionals in this field. [Extracted from the article]

Researchers from the University of Zagreb conducted a meta-analysis on the relationship between three basic psychological needs (autonomy, competence, relatedness) and Big Five personality traits. The study included 16 primary studies with over 10,500 participants, revealing significant correlations between the needs and traits. The research concluded that this study is the first to empirically summarize the overlap between these constructs from two theoretical perspectives. For more information, readers can refer to the article "The Relationship Between Three Basic Psychological Needs and Big Five Personality Traits: a Meta-analysis" published in Current Psychology. [Extracted from the article]

A recent study from the Catholic University of Croatia examined the impact of anxiety and depression symptoms on the well-being of war-affected married couples. The research focused on war veterans with PTSD and their wives, revealing that husbands' higher anxiety and depression symptoms can reduce wives' personal well-being. The study suggests that special attention should be given to veterans' wives in clinical settings, even when the husband is the one seeking professional help. This peer-reviewed research sheds light on the unique challenges faced by couples living with the effects of trauma from war experiences. [Extracted from the article]

A recent study conducted at the University of Zagreb in Croatia examined the multiple factors involved in the etiology and clinical features of cheilitis, a condition affecting the lips. The study analyzed the prevalence of cheilitis, demographic factors, clinical features, patients' habits, psychological stress, systemic diseases, and vitamin levels in 130 subjects with cheilitis and 22 healthy subjects. The research found associations between certain habits and types of cheilitis, as well as higher levels of psychological stress in patients with herpetic cheilitis. This study provides valuable insights into the complex nature of cheilitis and its contributing factors. [Extracted from the article]

Researchers at the University of Zagreb in Croatia have conducted a study on the synthesis and characterization of new ferrocenylpyrazole analogs of curcumin. The compounds were evaluated for their antioxidant, electrochemical, and biological activities. While the compounds showed lower antioxidant activity compared to curcumin, they exhibited antiproliferative effects on tumor cells. The researchers suggest that compounds 10 and 12 could be further investigated for potential therapeutic use in reproductive tissue neoplasms. The study was supported by the Croatian Science Foundation and has been peer-reviewed. [Extracted from the article]

New research from Children's Hospital Zagreb in Croatia suggests that genetic factors play a significant role in the development of childhood cancer. Unlike adult cancers, pediatric cancers are more likely to have genetic variants that predispose individuals to the disease. Advances in molecular technologies have allowed for a "genotype-first" approach to diagnosing cancer predisposition syndromes, which can lead to tailored treatment, improved clinical outcomes, optimized surveillance, and better genetic counseling for affected children and their families. This research has been peer-reviewed and provides valuable insights into the genetic basis of childhood cancer. [Extracted from the article]

A systematic review conducted by researchers at the University Hospital Center Zagreb in Croatia provides new insights into primary hyperparathyroidism-induced acute pancreatitis (AP) during pregnancy. The study found that this condition is rare, and there are currently no diagnostic or treatment algorithms specifically for pregnant patients. The researchers collected data from 54 cases and found that early diagnosis and immediate intervention lead to excellent maternal and fetal outcomes. They recommend testing serum calcium levels during admission to ensure timely diagnosis and intervention. [Extracted from the article]

A report from Zagreb, Croatia discusses the relationship between epilepsy and mental health conditions such as mood disorders, depression, anxiety, and psychosis. The research emphasizes the need for a multidisciplinary approach to treating individuals with epilepsy due to the significant impact of psychiatric comorbidities on their well-being. The study also highlights the increased risk of suicidal behavior among epilepsy patients. Understanding the neurobiological mechanisms underlying these comorbidities can lead to improved therapeutic responses and quality of life for individuals with epilepsy. [Extracted from the article]

A recent report from the University of Zagreb in Croatia discusses the use of biomarkers to differentiate between responders and non-responders in patients with idiopathic normal-pressure hydrocephalus (iNPH) undergoing external lumbar drainage (ELD). The study found that changes in the concentrations of certain biomarkers, specifically amyloid-(3, total and phosphorylated tau proteins, were associated with changes in clinical condition. Patients who showed significant clinical improvement had higher concentrations of A beta 1-42 and a higher A beta 1-42/A beta 1-40 ratio. The findings suggest that an increase in A beta 1-42 concentration during ELD may be a positive prognostic factor for permanent CSF drainage in iNPH patients. [Extracted from the article]

A study conducted at the University of Zagreb in Croatia examined the use of effective microorganisms (EM-1) in aquaculture to assess their impact on heavy metal concentrations in fish pond water. The study found that the application of EM-1 resulted in significantly lower levels of certain heavy metals, such as aluminium, beryllium, copper, manganese, vanadium, iron, barium, boron, and uranium, in the experimental fish pond compared to the control fish pond. However, the levels of arsenic and strontium were significantly higher in the experimental pond. The research suggests that EM-1 has the potential to improve fish pond water quality by reducing the concentrations of specific heavy metals. [Extracted from the article]

A report from Sestre Milosrdnice University Hospital in Zagreb, Croatia discusses the rare occurrence of alternating hypothyroidism and hyperthyroidism in a pediatric patient. The case study focuses on a 12-year-old boy who experienced fluctuations in thyroid function over a period of six years. Despite persistently elevated thyroid peroxidase antibodies, thyroid stimulating hormone receptor antibodies were repeatedly negative. The research emphasizes the need for individualized therapeutic decisions based on clinical manifestations and thyroid function tests, regardless of the underlying cause. [Extracted from the article]

A report from Sestre Milosrdnice University Hospital in Zagreb, Croatia discusses the diagnosis of latent tuberculosis infection (LTBI) in children. The research highlights the importance of diagnosing LTBI, as it can lead to active tuberculosis (TB) in the future. The gold standard for LTBI detection is still undetermined, but new assays called interferon-gamma release assays (IGRAs) have shown promise. The performance of IGRA could be a key factor in deciding whether to use preventive therapy for LTBI in children. [Extracted from the article]

A study conducted by the University of Zagreb in Croatia examined the effects of a Tai Chi exercise program on pain, functional status, and quality of life in patients with osteoarthritis or inflammatory arthritis. The study included 28 participants who completed the training program, which consisted of 50 sessions over 25 weeks. The results showed that the program improved chest and spinal mobility in home-dwelling individuals with osteoarthritis or inflammatory arthritis. However, there were no significant changes in pain, stability and balance, muscular strength, or health-related quality of life. The study suggests that the Tai Chi exercise program is safe and beneficial for certain aspects of mobility in these patients. [Extracted from the article]

A recent study conducted by the University of Zagreb School of Medicine in Croatia focused on the impact of congenital cytomegalovirus infection (cCMV) on children. The study found that cCMV is a common cause of childhood disability and can lead to various neurodevelopmental outcomes. Symptoms such as microcephaly, hearing impairment, and intrauterine growth restriction were identified as important predictors of adverse outcomes. However, the study also highlighted that these symptoms are often overlooked or recognized late in clinical settings. This research provides valuable insights into the recognition and management of cCMV in children. [Extracted from the article]

A report from Children's Hospital Zagreb discusses the findings of a survey conducted as part of the Paediatric Rare Tumours Network-European Registry (PARTNER) project. The survey aimed to evaluate the registration and management of pediatric patients with very rare tumors (VRT) in European countries with low health expenditure average rates (LHEAR). The survey revealed significant differences in the registration and management of VRT patients, as well as inequalities in pathology review, clinical decisions, access to diagnostic and therapeutic procedures, and research on pediatric VRT. The research concludes that these disparities in technology access and use between European regions need to be addressed. [Extracted from the article]

A study conducted by the University of Zagreb in Croatia explored the differences in social anxiety experienced by individuals in online and offline interactions. The study involved 295 female social media users aged 18-35 and found that socially anxious individuals reported higher levels of social anxiety in offline interactions compared to online interactions. The researchers also examined the applicability of a cognitive-behavioral model of social anxiety to online interactions and found that it was mostly in line with their expectations. This research has been peer-reviewed and published in the journal Current Psychology. [Extracted from the article]

A recent study conducted at the University Hospital Centre Zagreb in Croatia explored the perspectives of healthcare professionals on end-of-life care in pediatric intensive care units (ICUs). The study found diverse attitudes and experiences among healthcare professionals regarding various aspects of end-of-life care, with some indicating infrequent involvement in life-sustaining treatment (LST) limitation discussions and decisions. The research highlights the need for clearer guidelines, legal frameworks, support mechanisms, and communication strategies to navigate the complex and ethically challenging terrain of end-of-life pediatric care. The study included a total of 103 participants from neonatal and pediatric ICUs in Croatia. [Extracted from the article]

A new report from researchers at the University of Zagreb in Croatia explores the effects of different rest intervals on muscle strength gains during resistance training. The study involved 26 healthy, strength-trained males who were randomly assigned to either a 1-minute rest interval or a 3-minute rest interval. The results showed that longer rest intervals led to higher increases in peak torque of the knee and elbow extensors and flexors at slower angular velocities. However, the study suggests that both shorter and longer rest intervals can yield significant strength enhancements, depending on individual goals and time constraints. [Extracted from the article]

A recent study conducted in Zagreb, Croatia examined the impact of a specific genetic polymorphism on the renal graft function in kidney transplant recipients treated with mycophenolic acid (MPA). The study found that patients with the reduced-function allele at the SLCO1B1 c.521T >C polymorphism did not differ from their wild-type counterparts in terms of renal outcomes and tolerability. The study also found that the rates of adverse renal outcomes and MPA-related adverse effects were low and similar in both groups. Overall, the study concluded that the SLCO1B1 c.521T >C polymorphism has no practical relevance for the renal graft function in patients treated with MPA. [Extracted from the article]

A new study conducted in Zagreb, Croatia, explores the association between reduced plasma brain derived neurotrophic factor (BDNF) concentration and cognitive decline in chronic schizophrenia and mild cognitive impairment (MCI). The study included 123 inpatients with schizophrenia, 123 patients with MCI, and 208 healthy control subjects. The results showed that BDNF concentration was lower in patients with schizophrenia and MCI compared to healthy controls, and reduced plasma BDNF was significantly associated with lower cognitive scores. The researchers suggest that further studies should be conducted to confirm these results and develop strategies to prevent cognitive decline in chronic schizophrenia. [Extracted from the article]

The article reports on research from the University of Zagreb in Croatia, that investigates photocleavable compounds known as photocages, specifically focusing on aminonaphthalene and aminoquinoline derivatives. It examines their photophysical properties, reactivity in releasing alcohols and carboxylic acids, and potential applications in organic synthesis and cancer research.

A report from Zagreb, Croatia discusses the increasing visibility of non-binary individuals and the need for inclusive policies and practices in Assisted Reproductive Technologies (ART). The research suggests that traditional ART services, designed for binary genders, must adapt to address the unique fertility needs of non-binary patients. This includes using gender-neutral language, providing comprehensive fertility assessments, and offering hormone therapy and fertility preservation options. The research emphasizes the importance of positive societal attitudes, inclusive environments in schools, and supportive legislation to prevent discrimination and promote mental health. Ensuring the well-being of children in non-binary families requires psychological support, inclusive healthcare, legal recognition, social support, and comprehensive education. [Extracted from the article]

Researchers at the University of Zagreb in Croatia have conducted a study on the influence of chirality on the self-assembly and biological activity of ferrocene-containing peptides. They found that changing the order of two amino acids in the dipeptide sequence altered the hydrogen bonding patterns and affected the antiproliferative activity of the peptides. The study highlights structural variations that could lead to increased biological activity in similar ferrocene-based bioconjugates. The research was supported by the Croatian Science Foundation and has been peer-reviewed. [Extracted from the article]

A study conducted by researchers at the University of Zagreb in Croatia focuses on occupant-centric control (OCC) systems in buildings. The study investigates occupant preferences in control systems, including control access, automation level preferences, interface design, and data sharing. The results show that 55.6% of occupants are willing to interact with OCC by sharing data, with key influences being attitudes, social norms, ease of use, and user trust. The study provides important insights for OCC designers and building control practitioners to prioritize occupant needs and preferences. [Extracted from the article]

A study conducted in Zagreb, Croatia examined the auditory brainstem response (ABR) findings of preschool children with different types of speech and language pathology. The study included 123 children diagnosed with speech language pathology and normal hearing, including those with developmental language disorder, autism spectrum disorder, articulation pathology, organic brain lesions, cognitive delay, and speech development delay. The study found that children with comprehension problems had longer ABR latencies, with the longest latencies observed in children with organic lesions and autism spectrum disorder. The research suggests a connection between language pathology and ABR latencies. This study has been peer-reviewed and published in Folia Phoniatrica et Logopaedica. [Extracted from the article]

A new report from the Rudjer Boskovic Institute in Zagreb, Croatia presents data on the use of radiophotoluminescent glass dosimeters (RPLDs) in measuring doses in therapeutic proton beams. The study evaluated the dose dependence, long-term fading, and response of two types of RPLDs (GD-352M and GD-302M) in different configurations. The results showed a linear dose response for both types of RPLDs, with negligible long-term fading. However, GD-352M exhibited an under-response compared to treatment planning system (TPS) doses, indicating the need for correction factors. The research concluded that both types of RPLDs showed a slight decrease in response with an increase in linear energy transfer (LET). [Extracted from the article]

A study conducted at the University of Zagreb in Croatia explores the role of the behavioral inhibition system in pathogen-induced disgust and its potential connection to frontal hemispheric asymmetries. The study found that individuals with high behavioral inhibition showed larger shifts in frontal asymmetry while viewing pathogen-related disgust-inducing stimuli, indicating a more reactive behavioral immune system. The researchers suggest further research to determine if there is evidence of a calibrated response between one's immune status and neural reactivity to pathogen threats. This study has been peer-reviewed and published in the journal Periodicum Biologorum. [Extracted from the article]

A report from Children's Hospital Zagreb in Croatia discusses the use of probiotics in the treatment of functional gastrointestinal disorders (FGID) in children. The most common FGIDs in children include infantile colic, constipation, functional abdominal pain (FAP), and irritable bowel syndrome (IBS). The research highlights the use of specific probiotics, such as Limosilactobacillus (L.) reuteri DSM 17938 and Bifidobacterium animalis subsp. lactis BB-12, for the treatment of infantile colic in breastfed infants. Limited evidence also suggests the potential benefits of Lacticaseibacillus rhamnosus GG (LGG) for IBS and L. reuteri DSM 17938 for FAP. This research has been peer-reviewed. [Extracted from the article]

A study conducted at Children's Hospital Zagreb in Croatia investigated the effects of an exercise program on the health-related quality of life (HRQoL) and sleep quality in children with inflammatory bowel disease (IBD) in remission. The study involved 42 pediatric IBD patients who participated in a 6-month home-based exercise program. The results showed that the exercise program led to a significant decrease in the prevalence of impaired sleep quality, but did not have a significant impact on HRQoL scores. This research suggests that exercise may improve sleep quality in children with IBD. [Extracted from the article]

A study conducted by researchers at the Rudjer Boskovic Institute in Zagreb, Croatia, explores the sex-related differences in the oxidant and antioxidant profiles of murine kidney and brain, with a focus on the regulation of Sirt3. The study found significant sex- and organ-specific differences in response to Sirt3 loss, with kidneys being more affected than brain tissue. Female knockout mice showed lower levels of protein carbonylation and lipid peroxidation in the kidneys, but a larger decrease in these parameters in the brain compared to males. The research highlights the importance of considering tissue-specific responses and sex-related variations in the development of therapeutic strategies targeting mitochondrial function and redox homeostasis. [Extracted from the article]

A recent study conducted at the University of Zagreb in Croatia examined the effects of ischemic stroke on grafted Thy1-yfp-16 positive cells in mouse brains. The researchers induced stroke in mice and transplanted neural stem cells into their brains. They found a significant difference in the presence of certain neurons and astrocytes between the stroke group and the control group. The study suggests that Thy1-yfp-16 cells may be useful for transplantation and cell tracing studies. [Extracted from the article]

A study conducted by researchers at University Hospital Dubrava in Zagreb, Croatia, explores the concept of sensitivity to different types of threats in relation to mental health. The study suggests that some individuals are more sensitive to objective and widely accepted threats, known as "hard threats," while others are more sensitive to subjective and unpredictable threats, known as "soft threats." The research proposes that individuals who are sensitive to soft threats may be more resilient to hard threats. The study draws on data from outpatient visits following the 2020 Zagreb earthquake to support these hypotheses. The research has been peer-reviewed and is available in the journal New Ideas in Psychology. [Extracted from the article]

A report from researchers at the University of Zagreb discusses the impact of metamorphosis on the concentrations of pharmaceuticals and endocrine disruptors in caddisflies. The study found that adult caddisflies had the highest concentrations of these contaminants compared to larvae and pupae, indicating that metamorphosis plays a role in increasing the body burden of these compounds. The researchers emphasize the importance of including adult caddisflies in habitat quality assessments, as they can transport contaminants from aquatic to terrestrial environments. The study was funded by the Croatian Science Foundation and Unity through Knowledge Fund. [Extracted from the article]

A recent study conducted at the University Psychiatric Hospital Vrapce in Zagreb, Croatia, aimed to evaluate the subjective transition outcomes of transgender and gender-diverse individuals based on their transition status. The study divided 70 participants into two groups: those who had completed mandatory psychiatric and psychological evaluations and those who had undergone gender-affirming medical treatment. The results showed that individuals who had undergone gender-affirming medical care reported better overall functioning compared to those who had only completed the evaluations. Both groups reported high levels of satisfaction with their decision. The study suggests that gender-affirming medical care is beneficial to the overall functioning of transgender and gender-diverse individuals. [Extracted from the article]

A recent study conducted at the University of Zagreb in Croatia explored a novel biocatalytic route for the synthesis of a statin side chain precursor, which is used to lower blood cholesterol levels and combat cardiovascular disease. The researchers used an enzyme reaction engineering approach to determine the kinetics of the reactions involved in the cascade synthesis and optimize the process. Through simulations, they identified the best reactor mode and reaction conditions to achieve the highest yield of the desired product. This study provides valuable insights into the production of statins and offers an alternative synthesis route. [Extracted from the article]

A study conducted at Dubrava University Hospital in Zagreb, Croatia, examined the impact of a care transfer model led by a hospital clinical pharmacist on reducing hospital readmissions in elderly patients. The study included 182 patients in the intervention group and 171 in the control group. The results showed that the intervention group had significantly lower rates of hospital readmissions compared to the control group. The researchers concluded that hospital clinical pharmacists should play a role in designing and coordinating the transfer of care between hospitals and primary care. [Extracted from the article]