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The article focuses on a study which shows that a stem-cell-based, tissue-engineered tracheal transplant is a potential therapeutic option for patients. It mentions that patients treated with autologous stemcell-derived transplants do not need immunosuppression. It reflects that normal airway and lung function, high quality of life, and the elimination of the need for repeated surgical interventions were the end-points of a tracheal replacement in children.

Discusses the use of non-heart-beating donors for lung transplantation in the United Kingdom. Study published in the March 17, 2001 issue of the periodical 'Lancet;' Benefits of the research, including increased donor supply; Issues raised by the paper, including consensus on the ethics of the procedure; Feeling that units with patients who are potential donors must be prepared to revise their thinking to allow the procedures for organ preservation and retrieval and detailed functional assessment of the organ; Shortcomings of the paper.

A letter to the editor and the authors' reply are presented in response to the article "Stem-cell-based, Tissue Engineered Tracheal Replacement in a Child: A 2-year Follow-up Study," by Martin J. Elliott, P. De Coppi, and S. Speggiorin in the September 15, 2012 issue.