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Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study.

Authors :
Elliott, Martin J.
De Coppi, Paolo
Speggiorin, Simone
Roebuck, Derek
Butler, Colin R.
Samuel, Edward
Crowley, Claire
McLaren, Clare
Fierens, Anja
Vondrys, David
Cochrane, Lesley
jephson, Christopher
Janes, Samuel
Beaumont, Nicholas J.
Cogan, Tristan
Bader, Augustinus
Seifalian, Alexander M.
Hsuan, J. Justin
Lowdell, Mark W.
Birchall, Martin A.
Source :
Lancet. 9/15/2012, Vol. 380 Issue 3846, p994-1000. 7p.
Publication Year :
2012

Abstract

The article focuses on a study which shows that a stem-cell-based, tissue-engineered tracheal transplant is a potential therapeutic option for patients. It mentions that patients treated with autologous stemcell-derived transplants do not need immunosuppression. It reflects that normal airway and lung function, high quality of life, and the elimination of the need for repeated surgical interventions were the end-points of a tracheal replacement in children.

Details

Language :
English
ISSN :
01406736
Volume :
380
Issue :
3846
Database :
Academic Search Index
Journal :
Lancet
Publication Type :
Academic Journal
Accession number :
80124269
Full Text :
https://doi.org/10.1016/s0140-6736(12)60737-5