12 results on '"Yanhua Xu"'
Search Results
2. Factors influencing programming self-efficacy: an empirical study in the context of Mainland China
- Author
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Ziqi Zhu, Qingyue Li, Xue Sun, Yanhua Xu, and Jun Liu
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Mainland China ,Self-efficacy ,Programming education ,Empirical research ,Context (language use) ,Marketing ,China ,Psychology ,Education - Abstract
Programming self-efficacy plays an important role in promoting interest in programming education among teenagers. Therefore, the purpose of this study was to examine to what extent family socioecon...
- Published
- 2021
3. MiR-519d and miR-328-3p Combinatorially Suppress Breast Cancer Progression
- Author
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Tao Liu, Jin Wang, Xinying Wang, Haiming Ma, Yanhua Xu, and Xiaokang Liu
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0301 basic medicine ,medicine.diagnostic_test ,Cell growth ,Cell cycle ,Biology ,medicine.disease ,Flow cytometry ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Breast cancer ,Oncology ,Western blot ,030220 oncology & carcinogenesis ,Ki-67 ,microRNA ,medicine ,Cancer research ,biology.protein ,Pharmacology (medical) ,Wound healing - Abstract
Background MiR-519d and miR-328-3p had tumor-regulatory properties in different cancers, but their combinatorial effects and potential common target in breast cancer had not been fully reported. This research targeted to study the underlying mechanism of how miR-519d and miR-328-3p cooperatively suppressed breast cancer. Methods MiR-519d and miR-328-3p expressions in breast cancer tissues and cells were assessed and Ki-67 expression was also checked. DLR assay was executed to verify whether Ki-67 was a common target of miR-519d and miR-328-3p. Western blot, flow cytometry, colony formation, wound healing and transwell assays were applied to examine the inhibitory roles of these two miRNAs on the malignant behaviors of breast cancer cells and the potential molecular mechanism. Results Impeded miR-519d and miR-328-3p expressions and enhanced Ki-67 expression were detected in breast cancer tissues and cells. Ki-67 was confirmed as a target of these two miRNAs. MiR-519d and miR-328-3p hampered cell proliferation and blocked cell cycle via binding to Ki-67 and they also suppressed migration and invasion. The combinatorial effects of two miRNAs were much stronger than a single miRNA. Conclusion Our findings proved that miR-519d and miR-328-3p played combinatorial anti-cancer roles in breast cancer by directly targeting a common target Ki-67. Our study suggested that these two miRNAs might own the potential to become novel therapeutic biomarkers involved in the diagnosis and therapy of breast cancer.
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- 2020
4. Comprehensive Assessment of Plasma Circ_0004771 as a Novel Diagnostic and Dynamic Monitoring Biomarker in Gastric Cancer
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Yanhua Xu, Shan Kong, Xinyue Qin, and Shaoqing Ju
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0301 basic medicine ,Sanger sequencing ,medicine.medical_specialty ,Receiver operating characteristic ,business.industry ,Cancer ,medicine.disease ,Gastroenterology ,03 medical and health sciences ,symbols.namesake ,030104 developmental biology ,0302 clinical medicine ,Oncology ,Dynamic monitoring ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,symbols ,Biomarker (medicine) ,Diagnostic biomarker ,Pharmacology (medical) ,In patient ,Gastritis ,medicine.symptom ,business - Abstract
Purpose Due to the lack of specific and sensitive detection indicators, most patients with GC are already in the advanced stage at the time of diagnosis. Therefore, it is urgent to search for effective diagnostic biomarkers that can be applied in clinic. Materials and Methods We screened out circ_0004771 through circRNA sequencing. Exonuclease digestion assay, agarose gel electrophoresis (AGE) and Sanger sequencing verified the potential of circ_0004771 being a biomarker. Additionally, we established quantitative real-time fluorescent polymerase chain reaction (qRT-PCR) to detect the expression level of circ_0004771 and evaluated the methodology. What's more, we collected plasma samples from 120 GC patients, 40 superficial gastritis patients, 20 postoperative GC patients, 20 postoperative recurrence patients and 120 healthy donors. We constructed the receiver operating characteristic curve (ROC) to appraise its diagnostic efficacy. Results The expression level of circ_0004771 is up-regulated in GC tissues, which is consistent with circRNA sequencing result (P=0.0001). Circ_0004771 can serve as a promising biomarker because of its stable structure and longer half-life. Plasma circ_0004771 expression is markedly richer in GC patients than that in normal people (P
- Published
- 2020
5. Structure elucidation and NMR assignments of a new sesquiterpene of volatile oil from Artemisia frigida Willd
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Yanhua Xu, Xiang He, Biligetu Pa, Saranchimeg Borchuluun, Qinghu Wang, and Wenqiang Bao
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biology ,010405 organic chemistry ,Stereochemistry ,Organic Chemistry ,Plant Science ,Artemisia frigida ,biology.organism_classification ,Sesquiterpene ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Analytical Chemistry ,010404 medicinal & biomolecular chemistry ,chemistry.chemical_compound ,chemistry ,Two-dimensional nuclear magnetic resonance spectroscopy - Abstract
A new sesquiterpene, artefrigin (5), together with four known sesquiterpenes were isolated from the volatile oil of Artemisia frigida Willd. The structure of five was elucidated by spectroscopic methods, including UV, IR, HR-ESI-MS and extensive 1D and 2D NMR techniques.
- Published
- 2019
6. Efficient degradation of sulfamethoxazole by catalytic wet peroxide oxidation with sludge-derived carbon as catalysts
- Author
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Yide He, Yong Lv, Fuqing Wang, Yang Yu, Yongjun Zhang, Fei Huang, and Yanhua Xu
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Sulfamethoxazole ,0208 environmental biotechnology ,chemistry.chemical_element ,02 engineering and technology ,010501 environmental sciences ,urologic and male genital diseases ,01 natural sciences ,Peroxide ,Catalysis ,chemistry.chemical_compound ,medicine ,Environmental Chemistry ,Waste Management and Disposal ,0105 earth and related environmental sciences ,Water Science and Technology ,Sewage ,Natural water ,Sediment ,Hydrogen Peroxide ,General Medicine ,bacterial infections and mycoses ,Carbon ,female genital diseases and pregnancy complications ,Peroxides ,020801 environmental engineering ,chemistry ,Environmental chemistry ,Degradation (geology) ,Oxidation-Reduction ,Water Pollutants, Chemical ,medicine.drug - Abstract
Sulfamethoxazole (SMX) is a commonly used antibiotic for both human and animals. The frequent detection of SMX in natural water bodies and sediment has become an issue of great environmental concern due to its potential risk to induce antibiotic resistance in pathogenic bacteria. In the present work, the catalytic wet peroxide oxidation (CWPO) was investigated to remove SMX with sludge-derived carbon (SC) as a cheap alternative catalyst. Different acids were used to modify SC. It was found that SC modified with sulphuric acid (SC-H2SO4) demonstrated the best catalytic activity. The removal efficiency of SMX and TOC was 97.7% and 65.7%, respectively, after 260 min, at pH 5 with a dosage of 220 mg/L H2O2. The effects of temperature, initial pH and H2O2 dosage were also investigated. The study demonstrated that the increase of temperature could significantly improve the degradation of SMX from 10.0% at 20°C to 94.7% at 60°C.
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- 2018
7. Preparation and study on the photocatalytic mechanism of ZnFe2O4/Ag3PO4composite photocatalysts
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Haiqin Zhou, Zhu Mingxin, Jie Yang, Hairong Chu, and Yanhua Xu
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Optical absorbance ,Materials science ,Mechanical Engineering ,Composite number ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Chemical engineering ,Mechanics of Materials ,Photocatalysis ,General Materials Science ,0210 nano-technology - Abstract
In order to solve the disadvantages of most of the photocatalyst, ZnFe2O4 is chosen as the magnetic material and prepared ZnFe2O4/Ag3PO4 composite photocatalysts. ZnFe2O4 is prepared by hydrotherma...
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- 2018
8. Plasma-induced synthesis of chitosan-g-polyacrylamide and its flocculation performance for algae removal
- Author
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Huaili Zheng, Mengjiao Ren, Zhiying Liu, Yongjun Sun, Hui Zhu, Yanhua Xu, Xuefeng Xiao, Huifang Wu, and Wenquan Sun
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Flocculation ,0208 environmental biotechnology ,Polyacrylamide ,Acrylic Resins ,macromolecular substances ,02 engineering and technology ,Wastewater ,010501 environmental sciences ,01 natural sciences ,Chitosan ,chemistry.chemical_compound ,Algae ,Copolymer ,Environmental Chemistry ,Waste Management and Disposal ,0105 earth and related environmental sciences ,Water Science and Technology ,biology ,technology, industry, and agriculture ,General Medicine ,biology.organism_classification ,Environmentally friendly ,020801 environmental engineering ,chemistry ,Acrylamide ,Nuclear chemistry - Abstract
Chitosan (CS)-g-polyacrylamide (PAM) is a highly efficient and environmentally friendly flocculant, which was synthesized through plasma-induced graft copolymerization of CS and acrylamide (AM). The effects of monomer concentration, AM:CS ratio, discharge power, discharge time, post-polymerization temperature, and post-polymerization time on the intrinsic viscosity, grafting ratio, and grafting efficiency of CS-g-PAM were investigated. The optimum conditions of graft copolymerization were as follows: 20% monomer concentration, 7:3 AM:CS ratio, 40 W discharge power, 90 s discharge time, 50°C post-polymerization temperature, and 24 h post-polymerization time. The structural characteristics of CS-g-PAM were characterized by Fourier-transform infrared spectroscopy, scanning electron microscopy, and X-ray diffraction. CS-g-PAM exhibited better flocculation efficiency than the commercially available PAM in both diatomite-simulated wastewater and low-turbidity algal water. The optimal turbidity removal efficiency for the diatomite-simulated wastewater was 99.9%, which was obtained with 6 mg L
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- 2017
9. Preparation of HPW-CS/TiO2/FACS photocatalysts for degradation of tetracycline hydrochloride
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Zhu Mingxin, Yanhua Xu, Hairong Chu, Henghui Zhou, and Jun Yang
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Materials science ,Mechanical Engineering ,Inorganic chemistry ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Chitosan ,chemistry.chemical_compound ,Tetracycline Hydrochloride ,chemistry ,Mechanics of Materials ,Titanium dioxide ,Photocatalysis ,Degradation (geology) ,General Materials Science ,0210 nano-technology ,Molecular imprinting ,Photodegradation ,Nuclear chemistry - Abstract
Molecular imprinting technology in combination with photodegradation technology was applied to synthetize HPW-CS/TiO2/FACS photocatalysts. The novel photocatalyst could not only exhibit high photoc...
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- 2017
10. Molecular simulations and critical pH studies for the interactions between 2-phosphonobutane-1,2,4-tricarboxylic acid and calcite surfaces in circular cooling water systems
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Yanhua Xu, Jianping Zhao, and Jiaomei Jiang
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chemistry.chemical_classification ,Calcite ,Carboxylic acid ,Binding energy ,Inorganic chemistry ,Ocean Engineering ,02 engineering and technology ,Tricarboxylic acid ,021001 nanoscience & nanotechnology ,Pollution ,Crystallography ,chemistry.chemical_compound ,Adsorption ,020401 chemical engineering ,chemistry ,Chemisorption ,Carbonate Ion ,0204 chemical engineering ,0210 nano-technology ,Phosphoric acid ,Water Science and Technology - Abstract
The adsorption of 2-phosphonobutane-1,2,4-tricarboxylic acid (PBTC) on calcite surfaces (), (1 0 2), (1 0 4), (1 1 3), (2 0 2) was studied by molecular simulation. The phosphoric acid and carboxylic acid functional groups energetically interacted with the faces and preferentially occupied the carbonate ion sites by chemisorption, which is in agreement with the critical pH experiments. The strength of adsorption followed the order of () > (1 1 3) > (1 0 2) > (2 0 2) > (1 0 4). The binding energy gradually decreased with increasing temperature. The relationship between the critical pH and the adsorbed PBTC2โ configuration indicates that the adsorbed inhibitor configuration plays an important role in inhibitor efficiency.
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- 2014
11. Analysis and prediction of elastic constants of co-woven-knitted fabric (CWKF) composite
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Yanhua Xu, Hong Hu, and Xinlin Yuan
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Materials science ,Polymers and Plastics ,business.industry ,Materials Science (miscellaneous) ,Composite number ,Micromechanics ,Stiffness ,Structural engineering ,Yarn ,Industrial and Manufacturing Engineering ,Matrix (mathematics) ,Volume (thermodynamics) ,visual_art ,Ultimate tensile strength ,visual_art.visual_art_medium ,medicine ,Textile composite ,Composite material ,medicine.symptom ,General Agricultural and Biological Sciences ,business - Abstract
This paper presents an analytical and numerical model for the prediction of tensile elastic constants of a novel textile structural composite, namely co-woven-knitted fabric (CWKF) composite. Based on the CWKF geometry model previously developed, the direction angles of basic-cells of the weft, warp, and stitch yarn components in a representative volume elementary were determined. The micromechanics method and both isostrain and isostress conditions were applied to the yarn and the pure resin components, and the overall stiffness or compliance matrix of the composite was obtained. The normal elastic constants were calculated and compared with the experimental ones. The results showed that the relative errors between the calculated and the tested values are at an acceptable level (
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- 2013
12. Construction of a genetically engineered microorganism with high tolerance to arsenite and strong arsenite oxidative ability
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Yanhua Xu, Lin Xu, Chunyan Yang, and Limin Yan
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Environmental Engineering ,endocrine system diseases ,Arsenites ,Genetic Vectors ,Oxidative phosphorylation ,Biology ,Microbiology ,law.invention ,chemistry.chemical_compound ,law ,Cloning, Molecular ,DNA Primers ,Arsenite ,chemistry.chemical_classification ,Oxidase test ,Base Sequence ,Organisms, Genetically Modified ,Thermus thermophilus ,Wild type ,General Medicine ,biology.organism_classification ,Adaptation, Physiological ,Genetically modified organism ,Enzyme ,chemistry ,Recombinant DNA ,Oxidoreductases ,Oxidation-Reduction - Abstract
Genetically engineered microorganisms (GEMs) have shown great potential for use in environmental bioremediation. In this study, the TTHB128 and TTHB127 genes, which encode the small and large subunits of arsentie oxidase in Thermus thermophilus HB8, respectively, were cloned into the broad-host-range vector pBBR1MCS-5 to produce the recombinant plasmid, TTHB127-pBBR1MCS-5-TTHB128. This resulted in successful construction of a GEM with high tolerance to arsenite and strong arsenite oxidative ability. Culture of the GEM in media containing arsenite for 28 h resulted in 87.6% of the arsenite being oxidized. Overall, the oxidative ability of the GEM was much stronger than that of the wild type host strain. Gentamicin was necessary to maintain the stability of the recombinant plasmid, TTHB127-pBBR1MCS-5-TTHB128, in the GEM. The oxidative ability of the GEM remained unchanged when it was grown in medium containing gentamicin (60 mg/L) for 30 growth cycles, after which its activity gradually decreased.
- Published
- 2010
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