9 results on '"Tamburino, Corrado"'
Search Results
2. Percutaneous Mitral Valve Repair in Patients with Prior Cardiac Surgery
- Author
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Scandura, Salvatore, primary, Ussia, Gian Paolo, additional, Caggegi, Anna, additional, Mangiafico, Sarah, additional, Cammalleri, Valeria, additional, Chiarandà, Marta, additional, Capranzano, Piera, additional, and Tamburino, Corrado, additional
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- 2012
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3. Effectiveness of MitraClip Therapy in Patients with Refractory Heart Failure.
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ADAMO, MARIANNA, BARBANTI, MARCO, CURELLO, SALVATORE, FIORINA, CLAUDIA, CHIARI, ERMANNA, CHIZZOLA, GIULIANO, CAPODANNO, DAVIDE, TAMBURINO, CORRADO, METRA, MARCO, and ETTORI, FEDERICA
- Subjects
HEART failure ,MITRAL valve insufficiency ,HEART valve prosthesis implantation ,SYSTOLIC blood pressure ,PULMONARY artery ,AORTIC valve insufficiency - Abstract
Objectives To assess outcomes for MitraClip therapy in patients with refractory heart failure (HF) and mitral regurgitation (MR) ≥3+. Background The beneficial role of Mitraclip also in patients with severe HF has been reported. Methods Out of 45 patients undergoing MitraClip implantation at our institute, 16 were on refractory HF defined as diuretics and/or inotropics infusion and/or IABP dependence (group A) or labile haemodynamic balance (group B). Results Patients were aged 69 ± 13 years and 75% were males. Group A (8 patients) had a mean hospitalization length before MitraClip procedure of 5333 days. Group B (8 patients) had a mean rate of hospitalization, in the last 50 days before procedure, of 254 days. Acute procedural success was observed in 94% of patients. All but one patients of group A were quickly weaned from pharmacologic and/or mechanical supports within 5 ± 3 days from procedure and discharged at 20±10 days. All patients of group B were discharged after 10±8 days from MitraClip. At 1 year: a) cumulative survival rate was 78%; b) all patients were in NYHA functional class ≤ II; c) residual MR ≤ 2 was observed in 90%; d) systolic pulmonary arterial pressure was significantly reduced compared to the baseline (from 5410 to 398; p = 0,008); e) significant reduction of cumulative HF hospitalization days in the post-procedure year (10 days) compared to the pre-implantation year (280 days; p = 0.023) was observed. Conclusions In patients with refractory HF and MR ≥3+, MitraClip implantation resulted in acute and persistent clinical benefit and net reduction of HF re-hospitalization. (J Interven Cardiol 2015;28:61-68) [ABSTRACT FROM AUTHOR]
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- 2015
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4. Impact on Prognosis of Periprocedural Bleeding after TAVI: Mid-Term Follow-Up of a Multicenter Prospective Study.
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MORETTI, CLAUDIO, D'AMICO, MAURIZIO, D'ASCENZO, FABRIZIO, COLACI, CHIARA, SALIZZONI, STEFANO, TAMBURINO, CORRADO, PRESBITERO, PATRIZIA, MARRA, SEBASTIANO, SHEIBAN, IMAD, and GAITA, FIORENZO
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HEART diseases ,AORTIC valve diseases ,ACUTE kidney failure ,AORTIC stenosis ,STROKE risk factors ,DIAGNOSIS ,THERAPEUTICS - Abstract
Aims Impact of periprocedural bleeding after transcatheter aortic valve implantation (TAVI) over mid-term prognosis remains still unclear. Methods Consecutive patients who underwent TAVI from May 2008 to July 2012 were prospectively included and stratified according to life-threatening (LT) and major bleeding (MB). Mid-term all-cause death was the primary end-point, and 30-day death, vascular complications, stroke, and acute kidney injury the secondary ones. All end-points were adjudicated according to VARC. Results Seven hundred fourteen patients with an average age of 81.9 ± 5.8 years were included. 130 (18%) patients suffered a LT, 112 (16%) a MB. A preprocedural GFR <30 ml/min and increasing diameter of sheaths were independent predictors of LT or MB, while transfemoral approach showed a protective effect (OR 0.42; CI: 0.26-0.68; P = 0.035). At 30 days LT (OR 3.3; CI: 1.1-9.7; P = 0.0026) and MB (OR 3.5; CI: 1.4-8.6; P = 0.007) bleeding along with GFR < 30 ml/min (OR 2.3; CI: 1.1-5.5; P = 0.04) were independent predictors of death, while bleeding did not impact survival on mid term (OR 0.9; CI: 0.47-1.7; P = 0.78; all CI 95%). Conclusion Periprocedural bleeding after TAVI was frequent and associated with an increased mortality after 30 days but not after mid-term follow-up. A preprocedural GFR < 30 ml/min was the most important predictor of bleeding, enabling risk stratification and choice of approach for these patients. (J Interven Cardiol 2014;27:293-299) [ABSTRACT FROM AUTHOR]
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- 2014
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5. Long-Term Clinical and Angiographic Results of Sirolimus-Eluting Stent in Complex Coronary Chronic Total Occlusion Revascularization: The SECTOR Registry.
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GALASSI, ALFREDO R., TOMASELLO, SALVATORE D., COSTANZO, LUCA, CAMPISANO, MARIA B., BARRANO, GIOMBATTISTA, and TAMBURINO, CORRADO
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ANGIOGRAPHY ,RAPAMYCIN ,SURGICAL stents ,REVASCULARIZATION (Surgery) ,ARTERIAL occlusions - Abstract
Background: Drug-eluting stents showed a better angiographic and clinical outcome in comparison with bare metal stent in chronic total occlusions (CTOs) percutaneous revascularization, however, great concerns still remain regarding the rate of restenosis and reocclusion in comparison with nonocclusive lesions. Aim: To evaluate angiographic and clinical outcomes after sirolimus-eluting stent (SES) implantation in the setting of a 'real world' series of complex CTOs. Methods and Results: From January 2006 to December 2008, 172 consecutive patients with 179 CTO lesions were enrolled into registry. Among these, successful recanalization was obtained in 144 lesions (80.4%) with exclusive SES implantation in 104 lesions. The 9-12 months angiographic follow-up was executed in 85.5% of lesions with evidence of angiographic binary restenosis in 16.8% of lesions. Total stent length and number of stent implanted were recognized as independent predictors of restenosis (odds ratio [OR] 4.7, 95% confidence interval [CI] 1.28-107.09, P = 0.02) and (OR 5.8, 95% CI 1.39-23.55, P = 0.01), respectively. The 2-year clinical follow-up showed rates of target lesion revascularization, non-Q wave myocardial infarction, and total major adverse cardiovascular events (MACEs) of 11.1%, 2%, and 13.1%, respectively. Cox proportional-hazard analysis showed diabetes as independent predictor of MACEs (hazard ratio [HR] 4.832; 95% CI, 0.730-0.861; P = 0.028). Conclusions: Data from this registry demonstrate the long-term efficacy and safety of SES implantation after complex CTOs recanalization. (J Interven Cardiol 2011;24:426-436) [ABSTRACT FROM AUTHOR]
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- 2011
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6. Does Occlusion Duration Influence Procedural and Clinical Outcome of Patients Who Underwent Percutaneous Coronary Intervention for Chronic Total Occlusion?
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Tomasello, Salvatore D., Costanzo, Luca, Campisano, Maria B., Barrano, Giombattista, Capodanno, Davide, Tamburino, Corrado, and Galassi, Alfredo R.
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DENTAL occlusion ,REGRESSION analysis ,CALCIFICATION ,ANGIOPLASTY ,BLOOD coagulation ,ASPIRIN ,PATIENTS - Abstract
Previous studies have reported that the indeterminable aging and long-duration occlusion are associated with procedural failure and adverse long-term outcome. We aimed to investigate the clinical impact of occlusion duration in a consecutive series of patients who underwent percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions. From October 2005 to June 2009, a total of 303 patients with 328 CTO lesions were consecutively treated achieving a success rate of 86.3%. The average of occlusion duration estimated in 62.5% of cases (known occlusion duration [KOD] patients, n = 188) was 29.8 ± 41.3 months. In the remaining 37.5% of cases, the occlusion duration was indeterminate (indetermination of occlusion duration [IOD] patients, n = 115). No influence of duration in procedural outcome was observed. Moreover, no differences of 1-year major adverse cardiac events (MACE) were observed between KOD and IOD patients. The multivariate COX regression analysis identified diabetes mellitus and multivessel coronary disease as independent predictors of 12-month MACE (HR 5.023; 95% CI 0.164-9.653; P = 0.025 and HR 0.801; 95% CI 0.109-0.909, P = 0.033). The analysis did not show any influence of IOD and long occlusion duration in the occurrence of MACE. Predictors of angiographic failure recognized with multivariate binary logistic were vessel diameter <2.5 mm (OR 5.3; 95% CI 1.19-8.91; P = 0.02), CTO length >20 mm (OR 6.3; 95% CI 1.22-9.54; P = 0.02), and severe calcification (OR 3.2; 95% CI 1.62-5.51; P = 0.03). IOD and long duration of CTO do not affect procedural and clinical outcome of patients who underwent CTO PCI. This marks the importance of considering PCI treatment, a reliable strategy in cases of IOD or long occlusion duration. (J Interven Cardiol 2011;24:223-231) [ABSTRACT FROM AUTHOR]
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- 2011
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7. Prognostic Value of Exercise Myocardial Scintigraphy in Patients with Coronary Chronic Total Occlusions.
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GALASSI, ALFREDO R., WERNER, GERALD S., TOMASELLO, SALVATORE D., AZZARELLI, SALVATORE, CAPODANNO, DAVIDE, BARRANO, GIOMBATTISTA, MARZA', FRANCESCO, COSTANZO, LUCA, CAMPISANO, MARIABARBARA, and TAMBURINO, CORRADO
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ARTERIAL occlusions ,MYOCARDIAL revascularization ,POSITRON emission tomography ,CORONARY disease ,HEART diseases - Abstract
Objectives: To evaluate the prognostic value of exercise myocardial scintigraphy in patients undergoing incomplete revascularization by means of percutaneous coronary intervention (PCI) with at least a residual chronic total occlusion (CTO) left untreated. Methods: Of 569 consecutive patients with multivessel disease undergoing myocardial scintigraphy after incomplete revascularization by PCI between March 1997 and December 2004, 126 (79% male, 64± 10 years) with ≥ 1 residual CTO fulfilled the eligibility criteria and entered in the study. Hard events defined as cardiac death and myocardial infarction, soft events defined as incidence of unstable angina and PCI procedures, and their composite were assessed at a median follow-up period of 44 months. Results: Hard events were observed in six patients (4.8%). All of them had severely abnormal perfusion defects detected by myocardial scintigraphy. Soft events occurred in 0 (0%), 10 (7.9%), and 15 (11.9%) patients with normal, mildly abnormal, and severely abnormal perfusion, respectively. In the Kaplan–Meier analysis, the log-rank test was statistically significant across patients stratified by summed stress score either in terms of hard, soft and hard, or soft events. Univariate and multivariate Cox proportional-hazards showed an incremental significant information when the scintigraphic variables were added to clinical, angiographic, left ventricular ejection fraction, and Duke treadmill score, for prediction of the composite of hard and soft cardiac events (P < 0.006). Conclusions: Among patients with a residual CTO left untreated after PCI, myocardial perfusion imaging provides significant independent information concerning the subsequent risk of cardiac events. (J Interven Cardiol 2010;23:139-148) [ABSTRACT FROM AUTHOR]
- Published
- 2010
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8. Recanalization of Complex Coronary Chronic Total Occlusions Using High-Frequency Vibrational Energy CROSSER Catheter as First-Line Therapy: A Single Center Experience.
- Author
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GALASSI, ALFREDO R, TOMASELLO, SALVATORE D., COSTANZO, LUCA, CAMPISANO, MARIA B., MARZ, FRANCESCO, and TAMBURINO, CORRADO
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ARTERIAL occlusions ,CATHETERS ,CORONARY disease ,CLINICAL competence ,HEART diseases - Abstract
Background: Several studies have illustrated the safety and the procedural outcome of high-frequency vibrational energy in guidewire refractory chronic total occlusions (CTOs). Aim: To evaluate the advantage of high-frequency vibrational energy device (CROSSER Catheter) use in coronary complex CTO revascularization as primary strategy. Methods: CROSSER was used as a primary approach if four or more unfavorable angiographic features were observed in the CTO lesions. Results: From May 2007 to February 2009, a CTO percutaneous intervention attempt was performed in 178 lesions of 171 patients (60.1 ± 8.9 age with 49.4 ± 7.2% in ejection fraction). Among these, the CROSSER was used in 46 complex CTO lesions of 45 patients (25.8% of cases) and in the remaining cases, typical CTO percutaneous coronary intervention techniques were employed. Clinical success was 84.8% in CROSSER group. Moreover, in the CROSSER group, no periprocedural myocardial infarction, perforation, or 30 days MACE was observed. In addition, the use of CROSSER was associated with lower time of procedure, time of fluoroscopy, and contrast load administration as compared with conventional techniques [88 ± 27 minutes vs 109 ± 38 minutes (P = 0.045), 39 ± 12 minutes vs 50 ± 27 minutes (P = 0.032), and 334 ± 122cc vs 408 ± 198cc (P = 0.05), respectively]. Conclusion: In the present study, the CROSSER System was safe and obtained a high rate of success in complex CTO similar to conventional dedicated guidewire techniques for noncomplex CTO; however, the CROSSER Catheter obtained CTO recanalization with lower contrast load administration, less time of procedure, and lower fluoroscopy exposure. (J Interven Cardiol 2010;23:130-138) [ABSTRACT FROM AUTHOR]
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- 2010
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9. A Novel 3-D Reconstruction System for the Assessment of Bifurcation Lesions Treated by the Mini-Crush Technique.
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GALASSI, ALFREDO R., TOMASELLO, SALVATORE D., CAPODANNO, DAVIDE, SEMINARA, DARIO, CANONICO, LUCIANA, OCCHIPINTI, MICHELE, and TAMBURINO, CORRADO
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ANGIOGRAPHY ,BLOOD vessels ,STENOSIS ,MEDICAL care ,MEDICAL radiography - Abstract
Background: Conventional two-dimensional angiography lacks the ability to properly image the true bifurcation geometry, and its percutaneous coronary intervention-induced changes in the clinical setting. Methods and Results: A novel three-dimensional reconstruction system was investigated by retrospectively analyzing 39 lesions in 35 consecutive patients with coronary bifurcation disease treated with the mini-crush technique. At baseline, significant correlations were proved between two- and three-dimensional systems in terms of either reference vessel diameter (R
2 = 0.68 and 0.29 for main and side branches, respectively), minimum lumen diameter (R2 = 0.73 and 0.36), stenosis diameter (R2 = 0.69 and 0.29), and lesion length (R2 = 0.48 and 0.58). These results were consistent with those observed after the procedure and at 8-month follow-up. Lesion length was significantly longer with the three-dimensional compared to the two-dimensional system for both main and side branches (P < 0.001, and P = 0.007, respectively). Conclusions: The three-dimensional quantitative reconstruction system may provide accurate evaluation of the complex curvilinear structure of bifurcation lesions when using a double stent technique. (J Interven Cardiol 2010;23:46–53) [ABSTRACT FROM AUTHOR]- Published
- 2010
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