Back to Search
Start Over
Effectiveness of MitraClip Therapy in Patients with Refractory Heart Failure.
- Source :
- Journal of Interventional Cardiology; Feb2015, Vol. 28 Issue 1, p61-68, 8p
- Publication Year :
- 2015
-
Abstract
- Objectives To assess outcomes for MitraClip therapy in patients with refractory heart failure (HF) and mitral regurgitation (MR) ≥3+. Background The beneficial role of Mitraclip also in patients with severe HF has been reported. Methods Out of 45 patients undergoing MitraClip implantation at our institute, 16 were on refractory HF defined as diuretics and/or inotropics infusion and/or IABP dependence (group A) or labile haemodynamic balance (group B). Results Patients were aged 69 ± 13 years and 75% were males. Group A (8 patients) had a mean hospitalization length before MitraClip procedure of 5333 days. Group B (8 patients) had a mean rate of hospitalization, in the last 50 days before procedure, of 254 days. Acute procedural success was observed in 94% of patients. All but one patients of group A were quickly weaned from pharmacologic and/or mechanical supports within 5 ± 3 days from procedure and discharged at 20±10 days. All patients of group B were discharged after 10±8 days from MitraClip. At 1 year: a) cumulative survival rate was 78%; b) all patients were in NYHA functional class ≤ II; c) residual MR ≤ 2 was observed in 90%; d) systolic pulmonary arterial pressure was significantly reduced compared to the baseline (from 5410 to 398; p = 0,008); e) significant reduction of cumulative HF hospitalization days in the post-procedure year (10 days) compared to the pre-implantation year (280 days; p = 0.023) was observed. Conclusions In patients with refractory HF and MR ≥3+, MitraClip implantation resulted in acute and persistent clinical benefit and net reduction of HF re-hospitalization. (J Interven Cardiol 2015;28:61-68) [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08964327
- Volume :
- 28
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Interventional Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 101005654
- Full Text :
- https://doi.org/10.1111/joic.12179