1. Bioorthogonal chemistry in bioluminescence imaging.
- Author
-
Godinat A, Bazhin AA, and Goun EA
- Subjects
- Animals, Firefly Luciferin analogs & derivatives, Genes, Reporter, Humans, Luciferases genetics, Luminescent Measurements, Oxidation-Reduction, Chemistry Techniques, Synthetic, Firefly Luciferin chemical synthesis, Firefly Luciferin metabolism, Fluorescent Dyes chemical synthesis, Fluorescent Dyes metabolism, Luciferases metabolism, Molecular Imaging methods
- Abstract
Bioorthogonal chemistry has developed significant over the past few decades, to the particular benefit of molecular imaging. Bioluminescence imaging (BLI) along with other imaging modalities have significantly benefitted from this chemistry. Here, we review bioorthogonal reactions that have been used to signific antly broaden the application range of BLI., (Copyright © 2018. Published by Elsevier Ltd.)
- Published
- 2018
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