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Bioorthogonal chemistry in bioluminescence imaging.
- Source :
-
Drug discovery today [Drug Discov Today] 2018 Sep; Vol. 23 (9), pp. 1584-1590. Date of Electronic Publication: 2018 May 18. - Publication Year :
- 2018
-
Abstract
- Bioorthogonal chemistry has developed significant over the past few decades, to the particular benefit of molecular imaging. Bioluminescence imaging (BLI) along with other imaging modalities have significantly benefitted from this chemistry. Here, we review bioorthogonal reactions that have been used to signific antly broaden the application range of BLI.<br /> (Copyright © 2018. Published by Elsevier Ltd.)
- Subjects :
- Animals
Firefly Luciferin analogs & derivatives
Genes, Reporter
Humans
Luciferases genetics
Luminescent Measurements
Oxidation-Reduction
Chemistry Techniques, Synthetic
Firefly Luciferin chemical synthesis
Firefly Luciferin metabolism
Fluorescent Dyes chemical synthesis
Fluorescent Dyes metabolism
Luciferases metabolism
Molecular Imaging methods
Subjects
Details
- Language :
- English
- ISSN :
- 1878-5832
- Volume :
- 23
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Drug discovery today
- Publication Type :
- Academic Journal
- Accession number :
- 29778694
- Full Text :
- https://doi.org/10.1016/j.drudis.2018.05.022