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3. Efficacy of immunomodulatory therapy with interferon-β or glatiramer acetate on multiple sclerosis-associated uveitis

Author

C. Macia-Badia, José García-Arumí, A. Segura-García, S. Pastor Idoate, Daniel Velazquez-Villoria, L. Velez-Escola, and G. Arcos-Algaba

Subjects
medicine.medical_specialty, Retinal vasculitis, business.industry, Multiple sclerosis, Inflammation, General Medicine, medicine.disease, Gastroenterology, Rash, 03 medical and health sciences, 0302 clinical medicine, Interferon, Internal medicine, 030221 ophthalmology & optometry, medicine, Intermediate uveitis, Glatiramer acetate, medicine.symptom, business, 030217 neurology & neurosurgery, Uveitis, medicine.drug
Abstract

Aim To analyze the role of interferon-β or glatiramer acetate in reducing the inflammatory episodes of intra-ocular inflammation in multiple sclerosis-associated uveitis. Method A study was conducted on a non-randomized, retrospective case series of 13 patients with proven multiple sclerosis and uveitis (minimum follow-up, 12 months). All patients were given immunomodulatory treatment (interferon-β or glatiramer acetate) to control the course of the multiple sclerosis. Patients were compared to themselves before initiating the treatment, in order to assess the difference in uveitis episodes. The main outcome measurements were the number of uveitis episodes with/without immunomodulatory treatment. Results Uveitis was bilateral in 10 (77%) out of 13 patients. Intermediate uveitis was observed in 11 patients, retinal vasculitis in 3 patients, and one patient was classified as a posterior uveitis. The patients had a mean of 4.15 ± 3.1 episodes of uveitis (range 1–10) during the follow-up period (148.6 ± 84.3 months). When compared to their pre-treatment status, patients on treatment with interferon-β or glatiramer acetate showed a significant decrease of 0.36 episodes of ocular inflammation per year ( p = 0.02). Mild side effects related to immunomodulatory treatment were observed in 6 (46%) patients, 3 (23%) patients with a flu-like syndrome, and 3 (23%) patients with a skin rash. Conclusions Interferon β or glatiramer acetate could be effective in reducing the uveitis episodes in patients with multiple sclerosis-associated uveitis, and was well tolerated in most patients.

Published
2017

4. Eficacia del tratamiento inmunomodulador con interferón-β o acetato de glatirámero en las uveítis asociadas a esclerosis múltiple

Author

L. Velez-Escola, A. Segura-García, S. Pastor Idoate, Daniel Velazquez-Villoria, C. Macia-Badia, G. Arcos-Algaba, and José García-Arumí

Subjects
0301 basic medicine, 03 medical and health sciences, Ophthalmology, 030104 developmental biology, 0302 clinical medicine, 030217 neurology & neurosurgery
Abstract

Resumen Objetivo Analizar la eficacia del interferon-β o acetato de glatiramero en reducir los episodios de inflamacion intraocular en pacientes con uveitis asociada a esclerosis multiple. Metodo Estudio no aleatorizado, retrospectivo de serie de casos de 13 pacientes con diagnostico definitivo de esclerosis multiple y uveitis (seguimiento minimo, 12 meses). Todos los pacientes fueron tratados con terapia inmunomoduladora (interferon-β o acetato de glatiramero) para controlar el curso de la esclerosis multiple. Los pacientes fueron comparados con ellos mismos antes de iniciar el tratamiento inmunomodulador para valorar la diferencia en los episodios de uveitis. Variable principal de medida: numero de episodios de uveitis con/sin tratamiento inmunomodulador. Resultados Los brotes de uveitis fueron bilaterales en 10 de 13 pacientes (77%). Once pacientes fueron clasificados como uveitis intermedias, 3 pacientes como vasculitis retiniana y un paciente como uveitis posterior. Los pacientes tuvieron una media de 4,15 ± 3,1 episodios de uveitis (rango 1-10) a lo largo del seguimiento (148,6 ± 84,3 meses). Los pacientes bajo tratamiento con interferon-β o acetato de glatiramero mostraron una reduccion significativa de 0,36 episodios de inflamacion intraocular al ano (p = 0,02) comparados con ellos mismos antes de iniciar el tratamiento. Seis pacientes (46%) mostraron efectos secundarios leves asociados al tratamiento inmunomodulador (3 pacientes [23%] sindrome seudogripal; 3 pacientes [23%] rash cutaneo). Conclusiones El interferon-β o acetato de glatiramero podrian ser efectivos en reducir los brotes de inflamacion intraocular en pacientes con uveitis asociada a esclerosis multiple, siendo bien tolerados por la mayoria de los pacientes.

Published
2017

5. Urine extracellular vesicle GATA2 mRNA alone and in a multigene test predicts initial prostate biopsy result

Author

Marc Carceles-Cordon, S. Santasusagna, Raffaella Pippa, Leonard G. Gomella, J. M. Prats, S. Pastor-Lopez, Kamlesh K Yadav, Ana Dominguez-Andres, Grace L. Lu-Yao, Costas D. Lallas, Benjamin E. Leiby, Veronica Rodriguez-Bravo, Joshua Banks, Ashutosh K. Tewari, Wm. Kevin Kelly, Josep Domingo-Domenech, and Jungreem Woo

Subjects
PCA3, Oncology, medicine.medical_specialty, Prostate biopsy, medicine.diagnostic_test, business.industry, Hematology, Extracellular vesicle, medicine.disease, TMPRSS2, Prostate-specific antigen, Prostate cancer, medicine.anatomical_structure, Prostate, Internal medicine, medicine, P-Chloroamphetamine, business
Abstract

Background Prostate specific antigen (PSA) detection in blood is widely used to screen for prostate cancer (PCa). However, PSA has limited utility in discriminating high risk tumors (Gleason score≥7) from indolent-low risk tumors, which leads to unnecessary biopsies and highlights the need to identify better biomarkers for the detection of clinically significant PCa. GATA2 is a pioneer transcription factors which expression is increased in high-risk prostate cancer (PCa), but its utility in discriminating for PCa remains untested. Methods To determine whether extracellular vesicle (EV) GATA2 mRNA provides clinically relevant information to distinguish PCa, we prospectively analyzed non-digital rectal exam (DRE) urine EV GATA2 mRNA levels from 165 males with suspicion of PCa prior to biopsy and correlated GATA2 levels alone and combined in a multigene (PCA3 and TMPRSS2) EV mRNA assay to biopsy result. Results Prostate origin of GATA2 mRNA detected in urine EVs was confirmed by observing that GATA2 mRNA levels significantly dropped after prostatectomy (p Conclusions Non-DRE urine EV GATA2 mRNA alone and in combination with other urine EV biomarkers in men with suspicion of PCa provides useful information to distinguish any cancer and high-risk PCa and may reduce the number of biopsies. Legal entity responsible for the study The authors. Funding NCI/NIH. Disclosure K. Yadav: Full / Part-time employment: SEMA4. A. Tewari: Research grant / Funding (self): Boston Scientific Corporation, Medtronic, Inc. (10/15/2013); Licensing / Royalties: DNA Based Bicistronic Vectors with Inducible and Constitutive Promoters - ID#: 160608, High Intensity Focus Ultrasound and CPG-Brachyury-siRNA for Treatment of Prostate Cancer - ID# 160403, Patent for a Catheterless Device and Approach, Uretheral Catheter; Leadership role: Global Prostate Cancer Research Foundation, Kalyani Prostate Cancer Institute, Peter Georgescu Foundation Award, Promaxo; Advisory / Consultancy: Roivant, Siemens. W.K. Kelly: Advisory / Consultancy: Sanofi, Foundation Medicine; Travel / Accommodation / Expenses: Janssen Oncology; Honoraria (self): Janssen Oncology, Constellation Pharmaceuticals; Research grant / Funding (institution): Sanofi, Novartis, Janssen Oncology, Bayer, Exelixis, Seattle Genetics, Endocyte. B.E. Leiby: Advisory / Consultancy: Bayer. L. Gomella: Honoraria (self), Advisory / Consultancy: Astellas/Janssen/Mdx Health/Strand; Research grant / Funding (self): FKD; Licensing / Royalties: Jefferson IP. All other authors have declared no conflicts of interest.

Published
2019

6. Neutrino searches at the Pierre Auger Observatory

Author

S. Pastor

Subjects
Physics, Pierre Auger Observatory, Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, Solar neutrino, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy, Cosmic ray, Astrophysics, Solar neutrino problem, Partícules (Física nuclear), Atomic and Molecular Physics, and Optics, Cosmic neutrino background, Neutrino detector, Observatory, High Energy Physics::Experiment, Astrophysics::Earth and Planetary Astrophysics, Neutrino
Abstract

The surface detector array of the Pierre Auger Observatory is sensitive to ultra-high energy neutrinos in the cosmic radiation. Neutrinos can interact in the atmosphere close to ground (down-going) and, for tau neutrinos, through the Earth-skimming mechanism (up-going) where a tau lepton is produced in the Earth crust that can emerge and decay in the atmosphere. Both types of neutrino-induced events produce an inclined particle air shower that can be identified by the presence of a broad time structure of signals in the water-Cherenkov detectors. We discuss the neutrino identification criteria used and present the corresponding limits on the diffuse and point-like source fluxes.

Published
2013

7. Late Holocene subsistence and social integration in Sierras of Córdoba (Argentina): the South-American ostrich eggshells evidence

Author

Matías E. Medina, S. Pastor, Eduardo Apolinaire, and Lucas Turnes

Subjects
Lesser rhea, Archeology, Resource (biology), Greater rhea, biology, film.editor, Subsistence agriculture, Consumption (sociology), biology.organism_classification, Archaeology, Geography, film, Rheidae, Zooarchaeology, Holocene
Abstract

Zooarchaeological research carried out on South-American ostrich eggshells from late pre-Hispanic site Arroyo Talainin 2 (ca. 1100–300 BP, Sierras of Cordoba, Argentina) is presented in this paper. The resource importance has been assessed focusing mainly on its economic and political dimensions for social-unit integration rather than its classical use as a seasonal indicator. Eggshells taxonomic identification was performed by quantifying shell-pore density, and determining two Rheidae species: greater rhea ( Rhea americana ) and lesser rhea ( Rhea pennata ). High frequencies of burned eggshell fragments indicate an unequivocal association between this resource and the human occupations recorded at this site. Regional-scale data suggests that egg consumption took place disassociated from the main-residential camps. These locations were rock-shelters occupied by small-dispersed household groups or large-group food processing and consumption sites such as Arroyo Talainin 2. Thus, a flexible approach for a food-consumption study is required to account for its spatial dimension. Only a regional-scale archaeological research will allow advances to be made in our understanding of the subsistence patterns and socio-political organization of late pre-Hispanic human societies.

Published
2011

10. 80 Value of specific IgE detection against the recombinant antigenic components of Aspergillus fumigatus in the diagnosis of allergic bronchopulmonary aspergillosis in adult patients with cystic fibrosis

Author

D. Hernandez Fernandez de Rojas, A. Gomez Perez, Carla Navarro, S. Pastor Rebenaque, G. Anguera de Francisco, and A. Solé

Subjects
Pulmonary and Respiratory Medicine, biology, Adult patients, business.industry, Immunoglobulin E, medicine.disease, biology.organism_classification, Cystic fibrosis, Aspergillus fumigatus, law.invention, Antigen, law, Pediatrics, Perinatology and Child Health, Immunology, biology.protein, Recombinant DNA, Medicine, Allergic bronchopulmonary aspergillosis, business, Value (mathematics)
Published
2017

11. Chemical interaction between carbon and titanium dissolved in liquid tin: crystal structure and reactivity of Ti 2 SnC with Al

Author

Jean Bouix, S. Pastor, C. Vincent, B.F. Mentzen, and H. Vincent

Subjects
Materials science, Ternary numeral system, Mechanical Engineering, Analytical chemistry, chemistry.chemical_element, Mineralogy, Condensed Matter Physics, chemistry, Mechanics of Materials, Aluminium, Phase (matter), X-ray crystallography, Metallography, General Materials Science, Tin, Powder diffraction, Titanium
Abstract

Chemical interaction between carbon and titanium dissolved in liquid tin was studied at temperatures higher than 1000°C. The phase equilibria in the ternary system graphite–titanium–tin were investigated by thermal analysis, metallography, X-ray diffraction and electron microprobe analysis. The isothermal section at 1200°C is proposed. At this temperature, carbon can react to yield a binary phase, TiC, or a ternary phase, Ti 2 SnC. The structure of Ti 2 SnC is proposed on the basis of powder diffraction X-ray data (space group: P6 3 /m.m.c.; hexagonal axes a =0.31626 nm, c =1.36789 nm). Some experiments realized by immersion of T300 fibres in Sn–Ti alloys show that the chemical reaction leads to either a single layer of TiC or a double-layer, TiC–Ti 2 SnC. The results demonstrate that the ternary phase is not stable in liquid aluminium.

Published
1998

12. Nucleosynthesis constraints on heavy vτ in the presence of annihilations to majorons

Author

S. Pastor

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, Big Bang nucleosynthesis, Nucleosynthesis, Tau neutrino, High Energy Physics::Phenomenology, High Energy Physics::Experiment, Limit (mathematics), Atomic and Molecular Physics, and Optics
Abstract

We show that in the presence of sufficiently strong $\nu_\tau$ annihilations to majorons, primordial nucleosynthesis constraints can not rule out any values of the $\nu_\tau$ mass up the present laboratory limit.

Published
1996

13. P25.03 Bed occupancy and methicillin-resistant Staphylococcus aureus infection rate in intensive care units: 2003–2008

Author

G. Santana-López, D. Bordonaba-Bosque, Souad Belkebir, M.J. Hernández-Navarrete, S. Pastor-Eixarch, and C. Lapresta-Moros

Subjects
Microbiology (medical), medicine.medical_specialty, Infectious Diseases, business.industry, Intensive care, Emergency medicine, Medicine, General Medicine, business, medicine.disease_cause, Methicillin-resistant Staphylococcus aureus, Infection rate, Bed Occupancy
Published
2010

15. 127 IMPACT ON HEALTH RELATED QUALITY OF LIFE OF RADICAL PROSTATECTOMY AND PROSTATE BRACHYTHERAPY IN PATIENTS WITH LOW AND INTERMEDIATE-RISK CLINICALLY LOCALIZED PROSTATE CANCER

Author

Asunción Hervás, S. Pastor, G. Sancho, E. Franco, J.F. Suárez, Ismael Herruzo, Ferran Guedea, Humberto Villavicencio, Aguiló F, Alfonso Mariño, A. Polo, M. Ferrer, and P. Fernandez

Subjects
Oncology, Health related quality of life, medicine.medical_specialty, Prostatectomy, business.industry, Urology, medicine.medical_treatment, medicine.disease, Prostate cancer, Internal medicine, medicine, In patient, Intermediate risk, business, Prostate brachytherapy
Published
2007

18. Ultrasonographic features of Type B Niemann-Pick disease

Author

S. Pastor Santoveña, M.C. Diaz-Ruidavets, J. Fernandez-Ramos, V. Comas, L.E. Rodriguez, and C.E. Gonzalez-Reimers

Subjects
Adult, Male, Pathology, medicine.medical_specialty, Hepatosplenomegaly, Spleen, Diagnosis, Differential, hemic and lymphatic diseases, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Histiocyte, Ultrasonography, Niemann-Pick Diseases, business.industry, Splenic Neoplasms, General Medicine, Mononuclear phagocyte system, medicine.disease, medicine.anatomical_structure, Splenomegaly, Bone marrow, Splenic disease, Differential diagnosis, medicine.symptom, business, Niemann–Pick disease
Abstract

Niemann-Pick disease is a sphingomyelin lipidosis, in which sphingomyelinase deficiency leads to accumulation of sphingomyelin in the mononuclear phagocyte system [ 11. Several forms of this disease have been described. In contrast with type A Niemann-Pick disease, type B is a relatively mild disorder with hepatosplenomegaly and, sometimes, pulmonary infiltrates. Liver, spleen, bone marrow and lymph nodes are diffusely infiltrated by microvacuolated histiocytes, which stain ‘sea-blue’ by May-Griinwald-Giemsa [2]. Diagnosis should be confirmed by enzyme assay in cultured tibroblasts. These patients usually undergo abdominal sonoraphy, as a part of the clinical evaluation of patients with enlarged spleen. As in other storage diseases, some sonographic features may be rather characteristic, although differential diagnosis should be made with many other splenic lesions. We report the ultrasonographic findings of a patient affected by Niemann-Pick type B disease, pointing out the differential diagnosis with other focal splenic lesions.

Published
1993

19. Identifying clouds over the Pierre Auger Observatory using infrared satellite data

Author

M. Zavrtanik, N. Nierstenhoefer, R. Dallier, F. Salamida, J. F. Valdés Galicia, K. H. Becker, I. De Mitri, A. Gascon Bravo, A. Saftoiu, D. Garcia-Gamez, S. T. Garcia Roca, B. Gookin, D. Melo, David Walz, D. Pakk Selmi-Dei, R. Sato, M. Niechciol, D. B. Tridapalli, A. Segreto, A.M. van den Berg, Darko Veberič, I. Rodriguez Cabo, B. Sarkar, J. L. Navarro, M. Videla, J. C. Diaz, M. A. Leigui de Oliveira, R. Tcaciuc, F. Montanet, J. C. dos Anjos, Petr Schovanek, D. Maurizio, J. C. Moreno, C. Aramo, Lorenzo Caccianiga, Y. Guardincerri, G. Müller, J.M. Chirinos, B. Rouillé-D'Orfeuil, Bruno Daniel, Pham Ngoc Diep, D. Garcia-Pinto, Radomir Smida, T. Yapici, J. J. Masías Meza, R. Gaior, S. H. Cheng, Heino Falcke, B. Tome, L. Buroker, J. Knapp, R. Bonino, J. Vicha, G. Wieczorek, A. Lopez Agüera, F. Diogo, F. Suarez, Sergio Dasso, T. Niggemann, R. M. de Almeida, P. Allison, A. Tapia, G. Cocciolo, H. Gemmeke, C. Rühle, V. de Souza, M. Unger, H. Wahlberg, L. Nellen, B. Zamorano Garcia, M. Buscemi, N. Scharf, V. Pirronello, F. Guarino, John Matthews, Peter Buchholz, M. S. A. B. Leão, C. Macolino, C. Hojvat, C. Morello, K. D. de Vries, D. Nosek, T. Yamamoto, R. M. Kieckhafer, C. Jarne, M. Tueros, J. Rautenberg, B. Revenu, Jan Ebr, M. Melissas, O. Wainberg, I.M. Brancus, D. Huber, S. Westerhoff, H. Glass, Marco Aglietta, W. C. Brown, A. Nelles, Jaime Alvarez-Muñiz, D. Schuster, M. A. Muller, Lu Lu, G. Marsella, D. Martraire, S. Gambetta, Peter L. Biermann, D. Harari, Alessandro Petrolini, B. Mitrica, M. Ludwig, J. Rosado, A. van Vliet, A. Tonachini, L. Nožka, A. Weindl, N. Hollon, V. Verzi, P. Brogueira, M. Urban, A. C. Rovero, C. Bleve, B. Keilhauer, V. H. Ponce, S. J. Sciutto, J. Schovancova, Paolo Privitera, L. Perrone, Jiri Chudoba, D. Torres Machado, H.O. Klages, G. Torralba Elipe, D. Kruppke-Hansen, B. Wundheiler, R. Krause, Gregory R Snow, Alina Mihaela Badescu, M. Oliveira, M. Ave, E. Trovato, J. Lozano Bahilo, Segev BenZvi, Corbin Covault, Maria-Teresa Dova, M. Gómez Berisso, R. C. Shellard, Azadeh Keivani, A. P. Ferguson, R. Alves Batista, C. Baus, A. Aminaei, Y. Petrov, J. Gitto, P. Hansen, A. Chiavassa, A. E. Herve, Lino Miramonti, Vincenzo Rizi, M. D. Rodríguez-Frías, Paul Sommers, R. Cester, B. J. Whelan, P. Gouffon, W. Rodrigues de Carvalho, M. Risse, D. Martello, M. Ziolkowski, O. Martínez Bravo, P. N. Dong, M. J. Cooper, F. Sánchez, M. Ambrosio, M. De Domenico, Jing Zhou, G. Toma, S. Mićanović, B. M. Baughman, L. R. Wiencke, T. A. Harrison, A. Porcelli, M. Tartare, J. W. Cronin, B. D. Fox, N. T. Thao, G. Parente, A. Gorgi, V. Marin, J. Espadanal, M. Palatka, P. W. Younk, A. Śmiałkowski, P. Pieroni, Peter Schiffer, V. Scherini, Nataliia Borodai, H. R. Marquez Falcon, Alejandro Almela, S. van Velzen, E. Menichetti, G. Matthiae, G. Varner, H. Spinka, Antonio Bueno, Sergio Pastor, I. M. Pepe, J. Oehlschläger, A. F. Barbosa, Maria Rita Coluccia, Miguel Mostafá, Dusan Mandat, Gualberto Avila, Ingomar Allekotte, Angela V. Olinto, M. Monasor, F. Arqueros, P. Necesal, P. Gonçalves, N. Palmieri, Markus Ahlers, J. K. Kulbartz, H. Rivera, E. Varela, N. Griffith, J. A.J. Matthews, Xavier Bertou, R. E. Burton, S. Jiraskova, T. Rossler, J. D. Swain, A. Menshikov, J. C. Marin, H. Schieler, A. Zepeda, R. Ulrich, Karl-Heinz Kampert, Antonella Castellina, E. M. Santos, Pedro Assis, A. Etchegoyen, K. Kadija, Carola Dobrigkeit, A. Insolia, M. Kleifges, D. Zavrtanik, I. Katkov, Javier Tiffenberg, J. Allen, E. Mayotte, R. Mussa, J. J. Beatty, P. Wahrlich, K. Louedec, J. Pȩkala, Mariangela Settimo, Iván Sidelnik, Alexey Yushkov, H. Dembinski, N. Fazzini, K. Weidenhaupt, J. Kleinfeller, Jose Chinellato, Alan Watson, M. I. Micheletti, T. Huege, A. Parra, S. J. De Jong, I. Zaw, O. Fratu, H. Cook, Jeffrey Brack, Olaf Scholten, P. Lautridou, M. Avenier, D. Thomas, Bruce R. Dawson, Y. N. Srivastava, Humberto Ibarguen Salazar, T. Hebbeker, Julien Aublin, A. Widom, D. LaHurd, F. Werner, P.O. Mazur, J. Alvarez Castillo, F. Sarazin, Elton J. G. Santos, K. Link, M. Prouza, Piotr Homola, P. Facal San Luis, Rúben Conceição, P. Abreu, M. Josebachuili, D. Ravignani, Miroslav Hrabovský, Daniel Kuempel, Carlos Escobar, R. F. Gamarra, A. Haungs, J. Neuser, J. R. T. de Mello Neto, E. J. Ahn, A. Letessier-Selvon, L. Molina-Bueno, E. Kemp, S. Le Coz, Luis A. Anchordoqui, J. L. Harton, D. Monnier Ragaigne, Lorenzo Cazon, S. Maldera, C. Pfendner, I. A. Minaya, A. Bellétoile, A. Schmidt, H. Martinez, O. Krömer, P. Mantsch, Z. Szadkowski, Ivone F. M. Albuquerque, Ke Fang, N. Pacheco, Lukas Middendorf, M. Platino, G. Navarra, J. Bäuml, C. E. Santo, Francisco J. Blanco, Johannes Schulz, G. Golup, N. Kunka, F. Gomez Albarracin, M. Pimenta, C. A. Moura, Brian Fick, H. Blümer, Balázs Kégl, Moritz Münchmeyer, G. Rodriguez Fernandez, A. D. Supanitsky, Hernán Asorey, Christopher B. Williams, G. C. Hill, M. Zimbres Silva, T. Šuša, I. C. Mariş, Ralph Engel, M. Plum, E. Petermann, D. Nitz, J. Stapleton, Miroslav Pech, J. Ridky, M. L. Díaz Castro, G. Farrar, S. Fliescher, A. Stutz, Pavel Horvath, Kai Daumiller, M. S. Sutherland, Rémi Bardenet, Petr Travnicek, P. Lebrun, L. Tomankova, Trent D. Grubb, Sofia Andringa, R. Meyhandan, M. Ortiz, R. J. Lauer, Juan Manuel Figueira, Roberta Colalillo, P. Ristori, A. G. Mariazzi, S. Jansen, B. García, Mario Scuderi, S. Messina, G. Salina, A. Curutiu, Tobias Winchen, R. López, Karen S. Caballero-Mora, Olivier Deligny, B. Caccianiga, S. Stanič, H. Schoorlemmer, P.F. Gómez Vitale, Martina Bohacova, Martin Erdmann, A. Dorofeev, Guenter Sigl, J. Sorokin, M. Blanco, C. E. Fracchiolla, Roger W Clay, D. D'Urso, L. Latronico, Corinne Berat, M. Giller, S. Navas, G. P. Guedes, K. B. Barber, M. Weber, U. Fröhlich, R. A. Vázquez, L. Valore, P. Karhan, P. A. Kasper, A. Filipčič, M. Straub, D. Maurel, Markus Roth, A. Shadkam, C. Timmermans, S. Petrera, J. R. Vázquez, A. F. Grillo, Juan Carlos D'Olivo, T. Pierog, J. Maller, Rossella Caruso, W. J. M. de Mello, A. Lucero, G. La Rosa, P. L. Ghia, Octavian Sima, J. G. Gonzalez, V. C. Holmes, D. Lebrun, R. Pesce, Jörg R. Hörandel, F. Salesa Greus, G. Cataldi, G. Garilli, D. Heck, L. Villaseñor, L. Martin, I. Lhenry-Yvon, S. Mollerach, E. Roulet, Marco Cilmo, B. Wilczyńska, W. Docters, Peter Gorham, R. Pelayo, L. Collica, S. Querchfeld, J. L. Kelley, E. D. Fraenkel, S. J. Saffi, L. Niemietz, L. del Peral, J. Roberts, O. Ravel, R. Piegaia, J. Rodriguez Martino, H. J. Mathes, G. De La Vega, O. Taşcǎu, J. Rodriguez Rojo, M. Szuba, F.G. Schröder, Enrique Zas, C. Di Giulio, Fernando Contreras, L. Caramete, M. Will, W. Tkaczyk, G. Yuan, S. Riggi, T. Antičić, J. Stasielak, S. Coutu, M. Lauscher, M. Pontz, A. C. Fauth, M. Stephan, H. Lyberis, Carla Bonifazi, Jose A. Bellido, B. Morales, Denise Boncioli, German Ros, B. Vargas Cárdenas, Maria Concetta Maccarone, T. Suomijärvi, J. Pallotta, E. J. Quel, Béatrice Fuchs, Niraj Dhital, I. Valiño, A. Filevich, P. T. Nhung, S. Grebe, R. Squartini, T. Paul, G. Medina-Tanco, G. van Aar, A. Criss, C. J. Todero Peixoto, M. Malacari, Yunrong Zhu, N. Krohm, Christian Glaser, H. Wilczyński, P. Billoir, Laboratoire SUBATECH Nantes (SUBATECH), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Unité Scientifique de la Station de Nançay (USN), Observatoire des Sciences de l'Univers en région Centre (OSUC), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire d'Orsay (IPNO), PIERRE AUGER, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes), Centre National de la Recherche Scientifique (CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers en région Centre (OSUC), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université d'Orléans (UO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Research unit Astroparticle Physics, P., Abreu, M., Aglietta, M., Ahler, E. J., Ahn, I. F. M., Albuquerque, I., Allekotte, J., Allen, P., Allison, A., Almela, J., Alvarez Castillo, J., Alvarez Muñiz, R., Alves Batista, M., Ambrosio, A., Aminaei, L., Anchordoqui, S., Andringa, T., Antičić, C., Aramo, F., Arquero, H., Asorey, P., Assi, J., Aublin, M., Ave, M., Avenier, G., Avila, A. M., Badescu, K. B., Barber, A. F., Barbosa, R., Bardenet, B., Baughman, J., Bäuml, C., Bau, J. J., Beatty, K. H., Becker, A., Bellétoile, J. A., Bellido, S., Benzvi, C., Berat, X., Bertou, P. L., Biermann, P., Billoir, F., Blanco, M., Blanco, Bleve, Carla, H., Blümer, M., Boháčová, D., Boncioli, C., Bonifazi, R., Bonino, N., Borodai, J., Brack, I., Brancu, P., Brogueira, W. C., Brown, P., Buchholz, A., Bueno, L., Buroker, R. E., Burton, M., Buscemi, K. S., Caballero Mora, B., Caccianiga, L., Caccianiga, L., Caramete, R., Caruso, A., Castellina, G., Cataldi, L., Cazon, R., Cester, S. H., Cheng, A., Chiavassa, J. A., Chinellato, J., Chirino, J., Chudoba, M., Cilmo, R. W., Clay, Cocciolo, Giuseppe, R., Colalillo, L., Collica, Coluccia, MARIA RITA, R., Conceição, F., Contrera, H., Cook, M. J., Cooper, S., Coutu, C. E., Covault, A., Cri, J., Cronin, A., Curutiu, R., Dallier, B., Daniel, S., Dasso, K., Daumiller, B. R., Dawson, R. M., de Almeida, M., De Domenico, S. J., de Jong, G., De La Vega, W. J. M., de Mello, J. R. T., de Mello Neto, DE MITRI, Ivan, V., de Souza, K. D., de Vrie, L., del Peral, O., Deligny, H., Dembinski, N., Dhital, C., Di Giulio, J. C., Diaz, M. L., Díaz Castro, P. N., Diep, F., Diogo, C., Dobrigkeit, W., Docter, J. C., D’Olivo, P. N., Dong, A., Dorofeev, J. C., dos Anjo, M. T., Dova, D., D’Urso, J., Ebr, R., Engel, M., Erdmann, C. O., Escobar, J., Espadanal, A., Etchegoyen, P., Facal San Lui, H., Falcke, K., Fang, G., Farrar, A. C., Fauth, N., Fazzini, A. P., Ferguson, B., Fick, J. M., Figueira, A., Filevich, A., Filipčič, S., Fliescher, B. D., Fox, C. E., Fracchiolla, E. D., Fraenkel, O., Fratu, U., Fröhlich, B., Fuch, R., Gaior, R. F., Gamarra, S., Gambetta, B., García, S. T., Garcia Roca, D., Garcia Gamez, D., Garcia Pinto, G., Garilli, A., Gascon Bravo, H., Gemmeke, P. L., Ghia, M., Giller, J., Gitto, C., Glaser, H., Gla, G., Golup, F., Gomez Albarracin, M., Gómez Berisso, P. F., Gómez Vitale, P., Gonçalve, J. G., Gonzalez, B., Gookin, A., Gorgi, P., Gorham, P., Gouffon, S., Grebe, N., Griffith, A. F., Grillo, T. D., Grubb, Y., Guardincerri, F., Guarino, G. P., Guede, P., Hansen, D., Harari, T. A., Harrison, J. L., Harton, A., Haung, T., Hebbeker, D., Heck, A. E., Herve, G. C., Hill, C., Hojvat, N., Hollon, V. C., Holme, P., Homola, J. R., Hörandel, P., Horvath, M., Hrabovský, D., Huber, T., Huege, A., Insolia, S., Jansen, C., Jarne, S., Jiraskova, M., Josebachuili, K., Kadija, K. H., Kampert, P., Karhan, P., Kasper, I., Katkov, B., Kégl, B., Keilhauer, A., Keivani, J. L., Kelley, E., Kemp, R. M., Kieckhafer, H. O., Klage, M., Kleifge, J., Kleinfeller, J., Knapp, R., Krause, N., Krohm, O., Krömer, D., Kruppke Hansen, D., Kuempel, J. K., Kulbartz, N., Kunka, G., La Rosa, D., Lahurd, L., Latronico, R., Lauer, M., Lauscher, P., Lautridou, S., Le Coz, M. S. A. B., Leão, D., Lebrun, P., Lebrun, M. A., Leigui de Oliveira, A., Letessier Selvon, I., Lhenry Yvon, K., Link, R., López, A., Lopez Agüera, K., Louedec, J., Lozano Bahilo, L., Lu, A., Lucero, M., Ludwig, H., Lyberi, M. C., Maccarone, C., Macolino, M., Malacari, S., Maldera, J., Maller, D., Mandat, P., Mantsch, A. G., Mariazzi, J., Marin, V., Marin, I. C., Mariş, H. R., Marquez Falcon, Marsella, Giovanni, Martello, Daniele, L., Martin, H., Martinez, O., Martínez Bravo, D., Martraire, J. J., Masías Meza, H. J., Mathe, J., Matthew, J. A. J., Matthew, G., Matthiae, D., Maurel, D., Maurizio, E., Mayotte, P. O., Mazur, G., Medina Tanco, M., Melissa, D., Melo, E., Menichetti, A., Menshikov, S., Messina, R., Meyhandan, S., Mićanović, M. I., Micheletti, L., Middendorf, I. A., Minaya, L., Miramonti, B., Mitrica, L., Molina Bueno, S., Mollerach, M., Monasor, D., Monnier Ragaigne, F., Montanet, B., Morale, C., Morello, J. C., Moreno, M., Mostafá, C. A., Moura, M. A., Muller, G., Müller, M., Münchmeyer, R., Mussa, G., Navarra, J. L., Navarro, S., Nava, P., Necesal, L., Nellen, A., Nelle, J., Neuser, P. T., Nhung, M., Niechciol, L., Niemietz, N., Nierstenhoefer, T., Niggemann, D., Nitz, D., Nosek, L., Nožka, J., Oehlschläger, A., Olinto, M., Oliveira, M., Ortiz, N., Pacheco, D., Pakk Selmi Dei, M., Palatka, J., Pallotta, N., Palmieri, G., Parente, A., Parra, S., Pastor, T., Paul, M., Pech, J., Pe¸kala, R., Pelayo, I. M., Pepe, Perrone, Lorenzo, R., Pesce, E., Petermann, S., Petrera, A., Petrolini, Y., Petrov, C., Pfendner, R., Piegaia, T., Pierog, P., Pieroni, M., Pimenta, V., Pirronello, M., Platino, M., Plum, V. H., Ponce, M., Pontz, A., Porcelli, P., Privitera, M., Prouza, E. J., Quel, S., Querchfeld, J., Rautenberg, O., Ravel, D., Ravignani, B., Revenu, J., Ridky, S., Riggi, M., Risse, P., Ristori, H., Rivera, V., Rizi, J., Robert, W., Rodrigues de Carvalho, I., Rodriguez Cabo, G., Rodriguez Fernandez, J., Rodriguez Martino, J., Rodriguez Rojo, M. D., Rodríguez Fría, G., Ro, J., Rosado, T., Rossler, M., Roth, B., Rouillé d’Orfeuil, E., Roulet, A. C., Rovero, C., Rühle, S. J., Saffi, A., Saftoiu, F., Salamida, H., Salazar, F., Salesa Greu, G., Salina, F., Sánchez, C. E., Santo, E., Santo, E. M., Santo, F., Sarazin, B., Sarkar, R., Sato, N., Scharf, Scherini, Viviana, H., Schieler, P., Schiffer, A., Schmidt, O., Scholten, H., Schoorlemmer, J., Schovancova, P., Schovánek, F. G., Schröder, J., Schulz, D., Schuster, S. J., Sciutto, M., Scuderi, A., Segreto, M., Settimo, A., Shadkam, R. C., Shellard, I., Sidelnik, G., Sigl, O., Sima, A., Śmiałkowski, R., Šmída, G. R., Snow, P., Sommer, J., Sorokin, H., Spinka, R., Squartini, Y. N., Srivastava, S., Stanič, J., Stapleton, J., Stasielak, M., Stephan, M., Straub, A., Stutz, F., Suarez, T., Suomijärvi, A. D., Supanitsky, T., Šuša, M. S., Sutherland, J., Swain, Z., Szadkowski, M., Szuba, A., Tapia, M., Tartare, O., Taşcău, R., Tcaciuc, N. T., Thao, D., Thoma, J., Tiffenberg, C., Timmerman, W., Tkaczyk, C. J., Todero Peixoto, G., Toma, L., Tomankova, B., Tomé, A., Tonachini, G., Torralba Elipe, D., Torres Machado, P., Travnicek, D. B., Tridapalli, E., Trovato, M., Tuero, R., Ulrich, M., Unger, M., Urban, J. F., Valdés Galicia, I., Valiño, L., Valore, G., van Aar, A. M., van den Berg, S., van Velzen, A., van Vliet, E., Varela, B., Vargas Cárdena, G., Varner, J. R., Vázquez, R. A., Vázquez, D., Veberič, V., Verzi, J., Vicha, M., Videla, L., Villaseñor, H., Wahlberg, P., Wahrlich, O., Wainberg, D., Walz, A. A., Watson, M., Weber, K., Weidenhaupt, A., Weindl, F., Werner, S., Westerhoff, B. J., Whelan, A., Widom, G., Wieczorek, L., Wiencke, B., Wilczyńska, H., Wilczyński, M., Will, C., William, T., Winchen, B., Wundheiler, T., Yamamoto, T., Yapici, P., Younk, G., Yuan, A., Yushkov, B., Zamorano Garcia, E., Za, D., Zavrtanik, M., Zavrtanik, I., Zaw, A., Zepeda, J., Zhou, Y., Zhu, M., Zimbres Silva, M., Ziolkowski, P. Abreu, M. Aglietta, M. Ahler, E.J. Ahn, I.F.M. Albuquerque, I. Allekotte, J. Allen, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, R. Alves Batista, M. Ambrosio, A. Aminaei, L. Anchordoqui, S. Andringa, T. Antičić, C. Aramo, F. Arquero, H. Asorey, P. Assi, J. Aublin, M. Ave, M. Avenier, G. Avila, A.M. Badescu, K.B. Barber, A.F. Barbosa, R. Bardenet, B. Baughman, J. Bäuml, C. Bau, J.J. Beatty, K.H. Becker, A. Bellétoile, J.A. Bellido, S. BenZvi, C. Berat, X. Bertou, P.L. Biermann, P. Billoir, F. Blanco, M. Blanco, C. Bleve, H. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, R. Bonino, N. Borodai, J. Brack, I. Brancu, P. Brogueira, W.C. Brown, P. Buchholz, A. Bueno, L. Buroker, R.E. Burton, M. Buscemi, K.S. Caballero-Mora, B. Caccianiga, L. Caccianiga, L. Caramete, R. Caruso, A. Castellina, G. Cataldi, L. Cazon, R. Cester, S.H. Cheng, A. Chiavassa, J.A. Chinellato, J. Chirino, J. Chudoba, M. Cilmo, R.W. Clay, G. Cocciolo, R. Colalillo, L. Collica, M.R. Coluccia, R. Conceição, F. Contrera, H. Cook, M.J. Cooper, S. Coutu, C.E. Covault, A. Cri, J. Cronin, A. Curutiu, R. Dallier, B. Daniel, S. Dasso, K. Daumiller, B.R. Dawson, R.M. de Almeida, M. De Domenico, S.J. de Jong, G. De La Vega, W.J.M. de Mello, J.R.T. de Mello Neto, I. De Mitri, V. de Souza, K.D. de Vrie, L. del Peral, O. Deligny, H. Dembinski, N. Dhital, C. Di Giulio, J.C. Diaz, M.L. Díaz Castro, P.N. Diep, F. Diogo, C. Dobrigkeit, W. Docter, J.C. D’Olivo, P.N. Dong, A. Dorofeev, J.C. dos Anjo, M.T. Dova, D. D’Urso, J. Ebr, R. Engel, M. Erdmann, C.O. Escobar, J. Espadanal, A. Etchegoyen, P. Facal San Lui, H. Falcke, K. Fang, G. Farrar, A.C. Fauth, N. Fazzini, A.P. Ferguson, B. Fick, J.M. Figueira, A. Filevich, A. Filipčič, S. Fliescher, B.D. Fox, C.E. Fracchiolla, E.D. Fraenkel, O. Fratu, U. Fröhlich, B. Fuch, R. Gaior, R.F. Gamarra, S. Gambetta, B. García, S.T. Garcia Roca, D. Garcia-Gamez, D. Garcia-Pinto, G. Garilli, A. Gascon Bravo, H. Gemmeke, P.L. Ghia, M. Giller, J. Gitto, C. Glaser, H. Gla, G. Golup, F. Gomez Albarracin, M. Gómez Berisso, P.F. Gómez Vitale, P. Gonçalve, J.G. Gonzalez, B. Gookin, A. Gorgi, P. Gorham, P. Gouffon, S. Grebe, N. Griffith, A.F. Grillo, T.D. Grubb, Y. Guardincerri, F. Guarino, G.P. Guede, P. Hansen, D. Harari, T.A. Harrison, J.L. Harton, A. Haung, T. Hebbeker, D. Heck, A.E. Herve, G.C. Hill, C. Hojvat, N. Hollon, V.C. Holme, P. Homola, J.R. Hörandel, P. Horvath, M. Hrabovský, D. Huber, T. Huege, A. Insolia, S. Jansen, C. Jarne, S. Jiraskova, M. Josebachuili, K. Kadija, K.H. Kampert, P. Karhan, P. Kasper, I. Katkov, B. Kégl, B. Keilhauer, A. Keivani, J.L. Kelley, E. Kemp, R.M. Kieckhafer, H.O. Klage, M. Kleifge, J. Kleinfeller, J. Knapp, R. Krause, N. Krohm, O. Krömer, D. Kruppke-Hansen, D. Kuempel, J.K. Kulbartz, N. Kunka, G. La Rosa, D. LaHurd, L. Latronico, R. Lauer, M. Lauscher, P. Lautridou, S. Le Coz, M.S.A.B. Leão, D. Lebrun, P. Lebrun, M.A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, R. López, A. Lopez Agüera, K. Louedec, J. Lozano Bahilo, L. Lu, A. Lucero, M. Ludwig, H. Lyberi, M.C. Maccarone, C. Macolino, M. Malacari, S. Maldera, J. Maller, D. Mandat, P. Mantsch, A.G. Mariazzi, J. Marin, V. Marin, I.C. Mariş, H.R. Marquez Falcon, G. Marsella, D. Martello, L. Martin, H. Martinez, O. Martínez Bravo, D. Martraire, J.J. Masías Meza, H.J. Mathe, J. Matthew, J.A.J. Matthew, G. Matthiae, D. Maurel, D. Maurizio, E. Mayotte, P.O. Mazur, G. Medina-Tanco, M. Melissa, D. Melo, E. Menichetti, A. Menshikov, S. Messina, R. Meyhandan, S. Mićanović, M.I. Micheletti, L. Middendorf, I.A. Minaya, L. Miramonti, B. Mitrica, L. Molina-Bueno, S. Mollerach, M. Monasor, D. Monnier Ragaigne, F. Montanet, B. Morale, C. Morello, J.C. Moreno, M. Mostafá, C.A. Moura, M.A. Muller, G. Müller, M. Münchmeyer, R. Mussa, G. Navarra, J.L. Navarro, S. Nava, P. Necesal, L. Nellen, A. Nelle, J. Neuser, P.T. Nhung, M. Niechciol, L. Niemietz, N. Nierstenhoefer, T. Niggemann, D. Nitz, D. Nosek, L. Nožka, J. Oehlschläger, A. Olinto, M. Oliveira, M. Ortiz, N. Pacheco, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, N. Palmieri, G. Parente, A. Parra, S. Pastor, T. Paul, M. Pech, J. Pe¸kala, R. Pelayo, I.M. Pepe, L. Perrone, R. Pesce, E. Petermann, S. Petrera, A. Petrolini, Y. Petrov, C. Pfendner, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, V.H. Ponce, M. Pontz, A. Porcelli, P. Privitera, M. Prouza, E.J. Quel, S. Querchfeld, J. Rautenberg, O. Ravel, D. Ravignani, B. Revenu, J. Ridky, S. Riggi, M. Risse, P. Ristori, H. Rivera, V. Rizi, J. Robert, W. Rodrigues de Carvalho, I. Rodriguez Cabo, G. Rodriguez Fernandez, J. Rodriguez Martino, J. Rodriguez Rojo, M.D. Rodríguez-Fría, G. Ro, J. Rosado, T. Rossler, M. Roth, B. Rouillé-d’Orfeuil, E. Roulet, A.C. Rovero, C. Rühle, S.J. Saffi, A. Saftoiu, F. Salamida, H. Salazar, F. Salesa Greu, G. Salina, F. Sánchez, C.E. Santo, E. Santo, E.M. Santo, F. Sarazin, B. Sarkar, R. Sato, N. Scharf, V. Scherini, H. Schieler, P. Schiffer, A. Schmidt, O. Scholten, H. Schoorlemmer, J. Schovancova, P. Schovánek, F.G. Schröder, J. Schulz, D. Schuster, S.J. Sciutto, M. Scuderi, A. Segreto, M. Settimo, A. Shadkam, R.C. Shellard, I. Sidelnik, G. Sigl, O. Sima, A. Śmiałkowski, R. Šmída, G.R. Snow, P. Sommer, J. Sorokin, H. Spinka, R. Squartini, Y.N. Srivastava, S. Stanič, J. Stapleton, J. Stasielak, M. Stephan, M. Straub, A. Stutz, F. Suarez, T. Suomijärvi, A.D. Supanitsky, T. Šuša, M.S. Sutherland, J. Swain, Z. Szadkowski, M. Szuba, A. Tapia, M. Tartare, O. Taşcău, R. Tcaciuc, N.T. Thao, D. Thoma, J. Tiffenberg, C. Timmerman, W. Tkaczyk, C.J. Todero Peixoto, G. Toma, L. Tomankova, B. Tomé, A. Tonachini, G. Torralba Elipe, D. Torres Machado, P. Travnicek, D.B. Tridapalli, E. Trovato, M. Tuero, R. Ulrich, M. Unger, M. Urban, J.F. Valdés Galicia, I. Valiño, L. Valore, G. van Aar, A.M. van den Berg, S. van Velzen, A. van Vliet, E. Varela, B. Vargas Cárdena, G. Varner, J.R. Vázquez, R.A. Vázquez, D. Veberič, V. Verzi, J. Vicha, M. Videla, L. Villaseñor, H. Wahlberg, P. Wahrlich, O. Wainberg, D. Walz, A.A. Watson, M. Weber, K. Weidenhaupt, A. Weindl, F. Werner, S. Westerhoff, B.J. Whelan, A. Widom, G. Wieczorek, L. Wiencke, B. Wilczyńska, H. Wilczyński, M. Will, C. William, T. Winchen, B. Wundheiler, T. Yamamoto, T. Yapici, P. Younk, G. Yuan, A. Yushkov, B. Zamorano Garcia, E. Za, D. Zavrtanik, M. Zavrtanik, I. Zaw, A. Zepeda, J. Zhou, Y. Zhu, M. Zimbres Silva, M. Ziolkowski, J., Alvarez Mu?iz, T., Anti?i?, Aramo, Carla, J., B?uml, A., Bell?toile, C., Bleve, H., Bl?mer, M., Boh??ov?, Buscemi, Mario, Cilmo, Marco, G., Cocciolo, Colalillo, Roberta, M. 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Subjects
[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Atmospheric Monitoring, Satellites, Infrared, Astronomy, Cloud cover, FOS: Physical sciences, Atmospheric monitoring, 01 natural sciences, Ciencias de la Tierra y relacionadas con el Medio Ambiente, Auger, purl.org/becyt/ford/1 [https], purl.org/becyt/ford/1.5 [https], Observatory, Clouds, 0103 physical sciences, Extensive air showers, 010306 general physics, DETECTOR, Instrumentation and Methods for Astrophysics (astro-ph.IM), Image resolution, Ciencias Exactas, Physics, Pierre Auger Observatory, UHE Cosmic Rays, atmosphere, 010308 nuclear & particles physics, [SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Física, Astronomy and Astrophysics, Ultra-high energy cosmic rays, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], INFRAVERMELHO, Experimental High Energy Physics, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Pierre Auger observatory, ultra-high energy cosmic rays, extensive air showers, atmospheric monitoring, clouds, satellites, Física nuclear, Satellite, Central Laser Facility, Extensive Air Showers, Astrophysics - Instrumentation and Methods for Astrophysics, Meteorología y Ciencias Atmosféricas, SYSTEM, CIENCIAS NATURALES Y EXACTAS
Abstract

We describe a new method of identifying night-time clouds over the Pierre Auger Observatory using infrared data from the Imager instruments on the GOES-12 and GOES-13 satellites. We compare cloud. identifications resulting from our method to those obtained by the Central Laser Facility of the Auger Observatory. Using our new method we can now develop cloud probability maps for the 3000 km(2) of the Pierre Auger Observatory twice per hour with a spatial resolution of similar to 2.4 km by similar to 5.5 km. Our method could also be applied to monitor cloud cover for other ground-based observatories and for space-based observatories. (C) 2013 Elsevier B.V. All rights reserved., The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and adminis- trative staff in Malargüe. We are very grateful to the following agencies and organiza- tions for financial support: Comisión Nacional de Energía Atómica, Fundación Antorchas, Gobierno De La Provincia de Mendoza, Municipalidad de Malargüe, NDM Holdings and Valle Las Leñas, in gratitude for their continuing cooperation over land access, Argentina; the Australian Research Council; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Financiadora de Estudos e Projetos (FINEP), Fundação de Amparo à Pesquisa do Estado de Rio de Janeiro (FAPERJ), Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Ministério de Ciência e Tecnolo- gia (MCT), Brazil; AVCR AV0Z10100502 and AV0Z10100522, GAAV KJB100100904, MSMT-CR LA08016, LG11044, MEB111003, MSM0021620859, LA08015, TACR TA01010517 and GA UK 119810, Czech Republic; Centre de Calcul IN2P3/CNRS, Centre Na- tional de la Recherche Scientifique (CNRS), Conseil Régional Ile-de- France, Département Physique Nucléaire et Corpusculaire (PNC- IN2P3/CNRS), Département Sciences de l’Univers (SDU-INSU/ CNRS), France; Bundesministerium für Bildung und Forschung (BMBF), Deutsche Forschungsgemeinschaft (DFG), Finanzministeri- um Baden-Württemberg, Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF), Ministerium für Wissenschaft und Forschung, Nordrhein-Westfalen, Ministerium für Wissenschaft, Forschung und Kunst, Baden-Württemberg, Germany; Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell’Istruzione, dell’Università e della Ricerca (MIUR), Italy; Consejo Nacional de Ciencia y Tecnología (CONACYT), Mexico; Ministerie van Ond- erwijs, Cultuur en Wetenschap, Nederlandse Organisatie voor Wet- enschappelijk Onderzoek (NWO), Stichting voor Fundamenteel Onderzoek der Materie (FOM), Netherlands; Ministry of Science and Higher Education, Grant Nos. N N202 200239 and N N202 207238, Poland; Portuguese national funds and FEDER funds with- in COMPETE - Programa Operacional Factores de Competitividade through Fundação para a Ciência e a Tecnologia, Portugal; Roma- nian Authority for Scientific Research ANCS, CNDI-UEFISCDI part- nership projects nr.20/2012 and nr.194/2012, project nr.1/ ASPERA2/2012 ERA-NET and PN-II-RU-PD-2011-3-0145-17, Roma- nia; Ministry for Higher Education, Science, and Technology, Slove- nian Research Agency, Slovenia; Comunidad de Madrid, FEDER funds, Ministerio de Ciencia e Innovación and Consolider-Ingenio 2010 (CPAN), Xunta de Galicia, Spain; The Leverhulme Foundation, Science and Technology Facilities Council, United Kingdom; Department of Energy, Contract Nos. DE-AC02-07CH11359, DE- FR02-04ER41300, DE-FG02-99ER41107, National Science Founda- tion, Grant No. 0450696, The Grainger Foundation USA; NAFO- STED, Vietnam; Marie Curie-IRSES/EPLANET, European Particle Physics Latin American Network, European Union 7th Framework Program, Grant No. PIRSES-2009-GA-246806; and UNESCO. We would like to thank the former Michigan Tech students: Nathan Kelley-Hoskins, Kyle Luck and Arin Nelson for their impor- tant contribution to the development of this paper. We would like to thank NOAA for the GOES satellite data that we freely down- loaded from their website. Also, we would like to mention in these acknowledgments Dr. Steve Ackerman and Dr. Tony Schreiner for very valuable conversations

Published
2013

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