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openaire: EC/H2020/788489/EU//BioELCell Funding Information: This work was supported by the National Key Research and Development Program of China ( 2019YFC1905900 ), the National Natural Science Foundation of China ( 31870566 ), the Jinan Innovation Team ( 2021GXRC023 ), and Taishan Scholars Program . OJR and ZD are grateful for the support received from the Canada Excellence Research Chair Program ( CERC-2018-00006 ), the Canada Foundation for Innovation (Project number 38623 ) and the European Research Council (ERC) under the European Union's Horizon 2020 Research and Innovation Program (grant agreement No 788489 ). Publisher Copyright: © 2022 Water waves are viable low-carbon and renewable sources of power that can be optionally combined with triboelectric nanogeneration (TENG). Herein, we report on the synthesis of a TENG device based on green wrinkled paper tribolayers (W-TENG) assembled in grids (G-TENG) with channels that enable contact-separation modes involving metal balls that roll in phase with the waves. The paper's wrinkle wavelength and amplitude were adjusted by using a crepe blade at a given angle with respect to a drying cylinder, as well as the speed and torque. Polar hierarchical superhydrophobic cellulose micro/nanostructures, proposed as positive tribolayers with enhanced contact area and triboelectric density. The negative (biodegradable) tribolayers were prepared by electrospinning aqueous suspensions of polyvinyl alcohol and poly (ethylene oxide) reinforced with cellulose nanofibers. The charge transfer by the W-TENG reached up to 40 nC in air and retained 27 nC under 85 % relative humidity, ~5 and 7 times higher than those measured in planar TENG counterparts. A G-TENG array charging time (100-μF capacitor) of ~188 s was measured when the voltage of the capacitor raised to ~1.5 V. Overall, we introduce a new, scalable TENG system that is demonstrated for its remarkable ability to harvest blue energy.

International audience; Epidemiological studies on statin use in relation to skin cancer risk are scarce and yielded conflicting results. We explored this association in Etude Epidémiologique auprès de femmes de l'Education Nationale, a prospective cohort of French women born in 1925–1950. Health and lifestyle data were self-reported biennially and matched with drug reimbursement data, allowing the identification of participants’ statin use since 2004. Multivariable cause-specific hazards regression models adjusted for skin cancer risk factors estimated hazard ratios with 95% confidence intervals. Over 2004–2014, 455 cutaneous melanoma, 1,741 basal cell carcinoma, and 268 squamous cell carcinoma cases were ascertained among 62,473 women. Compared with never use, there were no associations between ever use of statins and melanoma (hazard ratio = 1.16, 95% confidence interval = 0.94–1.44) or squamous cell carcinoma (hazard ratio = 0.89, 95% confidence interval = 0.66–1.19) risks and a decrease in basal cell carcinoma risk with ever use of statins (hazard ratio = 0.89, 95% confidence interval = 0.79–0.996). We found no trend of increasing or decreasing risks with dose, duration of use, time since first use, or age at first use and no statistically significant effect modification by pigmentary traits or residential UVR exposure. Because of the limited number of studies evaluating the associations between the use of statins and the risks of melanoma, basal cell carcinoma, and squamous cell carcinoma, these findings would deserve further investigation in other settings.

Background-\ud \ud The limited available literature suggests that sleep problems are linked to an increased risk of mild cognitive impairment (MCI). However, this association has been little studied to date in low-income settings.\ud \ud Objective-\ud \ud To investigate the association between sleep problems and MCI in a large sample of adults from six low-and middle-income countries (LMICs).\ud \ud Design-\ud \ud Cross-sectional.\ud \ud Setting-\ud \ud Study on Global Ageing and Adult Health (SAGE).\ud \ud Subjects-\ud \ud 32,715 individuals aged ≥50 years with preservation in functional abilities [age range 50–114 years; 51.7% females].\ud \ud Methods-\ud \ud MCI was defined using the National Institute on Aging-Alzheimer's Association criteria. Sleep problems were assessed by the question “Overall in the last 30 days, how much of a problem did you have with sleeping, such as falling asleep, waking up frequently during the night or waking up too early in the morning?” and categorized as “None”, “Mild”, “Moderate”, “Severe/Extreme”. Multivariable logistic regression analysis and meta-analysis were conducted.\ud \ud Results-\ud \ud Compared to no sleep problems, mild, moderate, and severe/extreme sleep problems were associated with significant 1.40, 1.83, and 2.69 times higher odds for MCI with similar associations being observed between age groups and sex. Severe/extreme sleep problems were positively associated with MCI (i.e., OR > 1) in the six countries studied with the overall estimate being OR = 1.80 (95% CI = 1.50–2.16), and a low level of between-country heterogeneity was observed (I2 = 28.2%).\ud \ud Conclusions-\ud \ud Sleep problems were associated with higher odds for MCI. Interventions to improve sleep quality among middle-aged and older adults in LMICs may be an effective strategy in reducing risk of MCI and dementia.