Search

Proteolysis targeting chimera (PROTAC) technology represents a groundbreaking development in drug discovery, leveraging the ubiquitin‒proteasome system to specifically degrade proteins responsible for the disease. PROTAC is characterized by its unique heterobifunctional structure, which comprises two functional domains connected by a linker. The linker plays a pivotal role in determining PROTAC's biodegradative efficacy. Advanced and rationally designed functional linkers for PROTAC are under development. Nonetheless, the correlation between linker characteristics and PROTAC efficacy remains under-investigated. Consequently, this study will present a multidisciplinary analysis of PROTAC linkers and their impact on efficacy, thereby guiding the rational design of linkers. We will primarily discuss the structural types and characteristics of PROTAC linkers, and the optimization strategies used for their rational design. Furthermore, we will discuss how factors like linker length, group type, flexibility, and linkage site affect the biodegradation efficiency of PROTACs. We believe that this work will contribute towards the advancement of rational linker design in the PROTAC research area. PROTAC represents a groundbreaking biotechnology in drug discovery. The characteristics of linker significantly impact the biodegradation efficiency of PROTAC, thereby governing the rational design of PROTAC. [Display omitted] [ABSTRACT FROM AUTHOR]

The absence of a consensus-based reference standard for urinary tract infection (UTI) research adversely affects the internal and external validity of diagnostic and therapeutic studies. This omission hinders the accumulation of evidence for a disease that imposes a substantial burden on patients and society, particularly in an era of increasing antimicrobial resistance. We did a three-round Delphi study involving an international, multidisciplinary panel of UTI experts (n=46) and achieved a high degree of consensus (94%) on the final reference standard. New-onset dysuria, urinary frequency, and urinary urgency were considered major symptoms, and non-specific symptoms in older patients were not deemed indicative of UTI. The reference standard distinguishes between UTI with and without systemic involvement, abandoning the term complicated UTI. Moreover, different levels of pyuria were incorporated in the reference standard, encouraging quantification of pyuria in studies done in all health-care settings. The traditional bacteriuria threshold (105 colony-forming units per mL) was lowered to 104 colony-forming units per mL. This new reference standard can be used for UTI research across many patient populations and has the potential to increase homogeneity between studies. [ABSTRACT FROM AUTHOR]

• Disorders of placentation are associated with a wide range of pathological manifestations. • Immune cells in the decidua are critical in the aetiopathogenesis of inadequate placentation. • Decidual cell immunophenotypes and function require multidisciplinary research. • Diagnostic and therapeutic options derived from these findings could improve perinatal outcomes. [ABSTRACT FROM AUTHOR]

We use an art-based approach to engage and involve members of African, African Caribbean and Muslim communities' in exploring barriers to accessing and using mental health services in the co creation and co-production of mental health communication material. A creative practice approach underpinned by the principles of participatory action research was used. Seven community-based interactive workshops were held between February and June 2022 at three community centres in Nottingham, UK Attendees were invited to take part in open discussions around the conceptualisations of mental health, well-being and emotional health and to draw or describe their experiences of accessing mental health services. Attendance was higher than anticipated, with 72 individuals from African, African Caribbean and Pakistan communities taking part in the workshops. What emerged was the low level of understanding of the services available in addressing mental health. In addition, it was felt that health professionals in the National Health Service (NHS) do not sufficiently acknowledge or consider the ethnic, social, cultural and economic factors influencing the mental health and emotional well-being of minoritised communities. Attendees critiqued and provided feedback on service providers' posters and leaflets. They commented on the lack of key information provided, the inclusion of what was viewed as irrelevant content and the use of unfamiliar terminology. Some attendees created mock-ups of what they believed a good poster should look like. A creative practice approach that follows the principles of participatory action research can play an important role in engaging members of minoritised communities in the co-production and co-design of services. This approach highlighted the need to establish trust and shared ownership among marginalized communities affected by inequities of mental health service provision. [ABSTRACT FROM AUTHOR]

Cheilitis is a relatively common lip disease with many etiologies and causes including concomitant mucocutaneous or systemic diseases, which needs multidisciplinary communication. The purpose of this study was to compare the scientometric characteristics of cheilitis publications by multidisciplinary specialists. All the papers on cheilitis were comprehensively retrieved from the Scopus database, and divided into three groups (dermatologists, stomatologists, and other scholars). There were 478 and 241 papers on cheilitis published by dermatologists and stomatologists, respectively. The total citation count was 5838 and the h index was 36 for cheilitis publications by dermatologists, and the total count was 2983 and the h index was 27 for cheilitis publications by stomatologists. Interestingly, we observed that dermatologists preferentially concerned contact cheilitis/dermatitis and plasma cell cheilitis, while stomatologists preferentially concerned cheilitis-related lip neoplasms including squamous cell carcinoma, dysplasia, and precancerous conditions. The most common disorder researched by both dermatologists and stomatologists was actinic cheilitis. The keywords such as patch test, cosmetic, edema, drug efficacy, toothpaste, lipstick, allergens, and granulomatous inflammation were common in dermatologists' publications; while the keywords such as protein expression, metabolism, risk factor, prevalence, malignant transformation, and carcinogenesis were common in stomatologists' publications. This study for the first time reported the scientometric characteristics of cheilitis as an interdisciplinary disease researched by specialists. It highlights that cheilitis-related specialists through reciprocal collaboration and communication will improve the patients' outcomes. [ABSTRACT FROM AUTHOR]

Behaviour is often the first response of organisms to rapid environmental change and can be a key mediator of ecological responses at higher organisational levels. Macroecology seeks to understand patterns and processes that emerge from the interaction of many smaller components, and behaviour is an important but understudied category of component. We propose the new field of macrobehaviour, which aims to unify behavioural ecology and macroecology. Researchers from both disciplines can take advantage of new tools, approaches, concepts, and data, and ultimately ask new interdisciplinary questions. We explore how integrating behavioural ecology and macroecology can provide fundamental new insight into both fields, with particular relevance for understanding ecological responses to rapid environmental change. We outline the field of macrobehaviour, which aims to unite these disciplines explicitly, and highlight examples of research in this space. Macrobehaviour can be envisaged as a spectrum, where behavioural ecologists and macroecologists use new data and borrow tools and approaches from one another. At the heart of this spectrum, interdisciplinary research considers how selection in the context of large-scale factors can lead to systematic patterns in behavioural variation across space, time, and taxa, and in turn, influence macroecological patterns and processes. Macrobehaviour has the potential to enhance forecasts of future biodiversity change. [ABSTRACT FROM AUTHOR]

Complex challenges face clinicians managing critically ill patients with burns, particularly in the context of enhancing outcomes after a stay in ICU. Compounding this, a dearth of research explores the specific and modifiable factors that impact early mobilization in the ICU environment. To explore the barriers and enablers of early functional mobilization for patients with burns in the ICU from a multidisciplinary perspective. A qualitative phenomenological study. Semi-structured interviews supplemented by online questionnaires conducted with 12 multidisciplinary clinicians (four doctors, three nurses and five physical therapists) who previously managed burn patients at a quaternary level ICU. Data were thematically analysed. Four main themes: patient, ICU clinicians, the workplace and the physical therapist were identified as impacting on early mobilization. Subthemes identified barriers or enablers to mobilization but all were strongly influenced by overarching theme of the clinician's "emotional filter." Barriers included high levels of pain, heavy sedation and low levels of clinician exposure to treating patients with burns. Enablers included higher levels of clinician's experience and knowledge about burn management and benefits of early mobilization; increased coordinated staff resources when undertaking mobilization; and, open communication and positive culture towards early mobilization across the multidisciplinary team. Patient, clinician and workplace barriers and enablers were identified to influencing the likelihood of achieving early mobilization of patients with burns in the ICU. Emotional support for staff through multidisciplinary collaboration and development of structured burns training program were key recommendations to address barriers and strengthen enablers to early mobilization of patients with burns in the ICU. • A multidisciplinary perspective on the mobilization of patients with burns in the ICU is provided. • Clinician emotions and experience were strong drivers in the decision to mobilize in ICU. • High levels of pain and sedation were identified as barriers to early mobilization. • Multidisciplinary communication and teamwork facilitate early mobilization in ICU. [ABSTRACT FROM AUTHOR]

A growing number of people not only need to be fed but must also be nourished better under conditions that hamper agricultural production such as climate change, unsustainable food consumption, and political crises. Micronutrients are important for human health, but raw materials such as fruits, vegetables, cereals, and their derived products are usually not measured for their nutrient content. Product quality is mainly defined by shelf-life, gustatory, and techno-functional properties. Food is a product of a more or less complex supply chain. Each stakeholder in that chain influences the quality and nutritional profile of the final product, with interactions between stakeholders. Multidisciplinary research and education about nutrients from farm to fork will be necessary to establish global supply chains for all food products, thus guaranteeing optimized and standardized nutritional profiles for better human nutrition in the future. In the future, 8–10 billion people will need to be fed by our agriculture and food production system. Moreover, currently up to five billion people are already affected by malnutrition including undernutrition, inadequate consumption of micronutrients, and overweight. A healthy and sustainable diet will therefore play a pivotal role in our future, but most food products are traded and consumed based only on techno-functional or gustatory properties. We wish to stimulate a debate on the urgent need for multidisciplinary research and education to realize future diets with enhanced nutritional profiles. In particular, there is a need to better measure and understand the factors that influence the nutrients of food products along the global supply chains. [ABSTRACT FROM AUTHOR]

Indigenous and local peoples' (ILPs) role in cataloging life on Earth has been significant but underappreciated. ILPs knowledge faces growing cultural and biological threats. Greater participation by ILPs in research would make science more efficient, conservation more sustainable, and traditional knowledge stronger, but formidable obstacles remain. [ABSTRACT FROM AUTHOR]

This meeting report presents the 2022 Annual Meeting of the cluster for Integrative Structural Biology at the University of Copenhagen (ISBUC) and discusses the cluster approach to interdisciplinary research management. This approach successfully facilitates cross-faculty and inter-departmental collaboration. Innovative integrative research collaborations ignited by ISBUC, as well as research presented at the meeting, are showcased. In this meeting report, Kragelund et al. present the 2022 Annual Meeting of the cluster for Integrative Structural Biology at the University of Copenhagen (ISBUC) and discuss the cluster approach to interdisciplinary research management. The report offers a blueprint for organizing interdisciplinary clusters by showcasing collaborations ignited by ISBUC and research presented at the meeting. [ABSTRACT FROM AUTHOR]

• The International Bladder Cancer Network (IBCN) celebrates its 25th anniversary. • The IBCN has evolved as a nidus for international, interdisciplinary research. • This Editorial briefly presents the IBCN and its mission. • In addition, 3 major topics in current bladder cancer research are introduced. [ABSTRACT FROM AUTHOR]

This article studies the reorganisation of research communities in a context characterised by tension between increasing calls for inter- and transdisciplinary research (ITDR) and the persistent structuring, functioning and evaluation of scientific research on a mainly disciplinary basis. We focus on the case of the French LTSER platforms, the 'Zones Ateliers' (ZAs), which are committed to ITDR on social-ecological systems, drawing on in-depth interviews with their leaders, analysis of their applications for creation or renewal and bibliometric data. We use the two concepts of boundary organisation and meta-organisation to analyse the organisational aspects of ZAs. We show that ZAs are not only quasi boundary organisations, as is often emphasised, but also research-based meta-organisations, which is ignored but has important implications for their functioning and dynamics. Our study also shows that ZAs have so far had a limited impact on the organisation of research communities, and that the levels of inter- and transdisciplinarity in their bodies, projects and publications have recently increased but remain relatively low. Our article contributes to the literature about LTSER platforms by exploring the relationship between their type of organisation and what they can achieve to promote ITDR. It also contributes to the literature about boundary organisations and meta-organisations, by clarifying their similarities and differences, as well as their limitations and added value for investigating the organisational aspects of initiatives to promote ITDR. • Organisation in ITDR matters and deserves attention. • The French LTSER platforms are quasi boundary organisations. • They are also meta-organisations with a strong base in the life sciences. • This limits what they can achieve as quasi boundary organisations. • Collective reflection is needed to better utilise the range of possible organisational arrangements. [ABSTRACT FROM AUTHOR]

Abstract Connecting academic libraries to the higher education environment is crucial for demonstrating the impact of libraries on student success. The purpose of this study is to examine the information transfer between the disciplines of library and information science (LIS) and higher education in order to evaluate the influence of ideas between the two disciplines. Information transfer was analyzed in 39 articles focused on the library's contributions to student success by examining the cited references, the author and collaborator affiliations, and the forward citations. The findings from the cited reference analysis suggest that LIS is borrowing concepts and methods through citations from the discipline of education. Authorship affiliations showed that some non-LIS authors are publishing in the field of LIS and that LIS authors are collaborating with non-LIS authors. Finally, based on the forward citations, other disciplines are rarely citing LIS research about student success. This article's findings highlight the need to consider research and collaborators outside of the LIS field when researching the library's contribution to student success. [ABSTRACT FROM AUTHOR]

This study focuses on the design optimization of a micro-scale pressurized volumetric receiver by changing geometry and flow rate constrained by the volume, outlet air temperature, and outer surface temperature. The pressurized volumetric receiver model is replicated from an existing model, which assumes constant air pressure and neglects the convection loss from the cavity. The existing model is revised from a solver to a design optimizer. The replicated model is restructured using OpenMDAO (Open-source MultiDisciplinary Analysis and Optimization) framework, and analytical derivatives are implemented for efficient derivative calculation to increase optimization performance. The replicated model is verified, and the maximum outlet air temperature difference is less than 0.05%. Optimization performance, selection of optimizers, the effect of the domain size, and radiative methods are discussed. The combined impact of the design variables is observed by selecting SLSQP (Sequential Least SQuares Programming) and trust-region optimizers. Optimization performance is tested in different domain sizes and compared with a design of experiments analysis. For testing the impact of radiative heat transfer methods to design optimization, the Rosseland approximation, and P 1 method are selected. Depending on the design domain, a solution methodology is suggested for future receiver design optimizations applicable for macro-scale pressurized volumetric receivers. • Gradient-based optimization is efficient for geometry and flow rate calculations. • SLSQP algorithm performs better in a larger domain. • Trust-region algorithm performs faster and better results for smaller domain. • Different radiation transfer models yield different optimization paths. • Method of design of experiments used to narrow down the design space. [ABSTRACT FROM AUTHOR]

Where there is behavior there are social norms. Social norms are a key feature of societies, and their adherence is crucial to sustaining social order. This special issue brings together research at the interdisciplinary research frontier investigating social norms with a focus on behavior change. We categorize research according to different methods (theory, non-experimental, laboratory, extra-laboratory) and discuss their policy implications. [ABSTRACT FROM AUTHOR]

Des inquiétudes grandissent depuis plusieurs années chez nos maîtres, quant à la qualité et à la quantité de la formation en chirurgie plastique en France. Elles se basent principalement sur la diminution du temps de travail des internes, l'apparition de nouveaux internes de la Génération Z à former, et enfin la pluridisciplinarité de la chirurgie plastique dans le contexte actuel de surspécialisation des services formateurs. Afin d'objectiver ces inquiétudes, un sondage a été réalisé parmi les internes et jeunes chefs de chirurgie plastique français pour évaluer leur formation à la spécialité depuis 2019. Nous avons ensuite recherché dans la loi, des possibilités pour pallier ces inquiétudes. Tous les répondants pensent que leur formation à la spécialité est incomplète, et peu d'entre eux ont pu la compléter par des stages hors subdivision ou des visites de praticiens privés. Or, dans la loi, il est possible de réaliser trois stages hors subdivisions, des stages hors Centre Hospitalo-Universitaire (CHU) en établissements privés de santé, et des stages ou échanges internationaux. Au terme de cette analyse, nous proposons trois solutions pour optimiser la formation en chirurgie plastique en France : un système d'échange d'internes, l'ouverture de terrains de stage dans des établissements privés de santé, et enfin, faciliter la réalisation d'aides opératoires auprès de praticiens libéraux. Avec ces solutions, le champ de formation des internes pourrait s'étendre d'une région à la France entière. Ces solutions pourraient aisément s'appliquer à d'autres spécialités, chirurgicales et médicales. Concerns have been growing for several years among masters, as to the quality and quantity of training in plastic surgery in France. They are mainly based on the reduction in the working time of residents, the appearance of new residents from generation Z to be trained, and finally the multidisciplinarity of plastic surgery in the current context of overspecialization of training center. In order to objectify these concerns, a survey was carried out among French residents and young heads of plastic surgery to assess their training in the specialty since 2019. We then looked in the law for possibilities to alleviate these concerns. All the respondents think that their training in the specialty is incomplete, and few of them have been able to supplement it with rotations outside the subdivision or visits from private practitioners. However, in the law, it is possible to carry out: three residents rotations outside the subdivision, clinics rotations and international exchanges. At the end of this analysis, we propose three solutions to optimize training in plastic surgery in France: a system of exchange of residents, the opening of residents rotations in clinics, and finally, to facilitate the realization of operating aids with private practitioners. With these solutions, the field of training for residents could extend from one region to the whole of France. These solutions could easily be applied to other specialties, surgical and medical. [ABSTRACT FROM AUTHOR]

Climate-driven disturbances threaten the sustainability of coastal communities in the Great Lakes Basin. Because such disturbances are unpredictable, their magnitude, number and intensity are changing, and they occur at varying temporal and spatial scales. Consequently, communities struggle to respond in effective ways. The expected intensification of climate-driven disturbances will require that community capacity and governance structures match the spatial and temporal scales of these disturbances, as the most sustainable social and economic systems will be those that can respond at similar frequencies to key natural system drivers. The Climate Governance Variability in the Great Lakes Research Coordination Network (CGVG-RCN) was recently established to address questions about the relationship between climate-driven disturbances and community response. The objective of this short communication is to introduce the ideas behind the CGVG-RCN, outline its goals, and facilitate engagements and collaboration with social and natural scientists interested in social-ecological systems in the Great Lakes Basin. [ABSTRACT FROM AUTHOR]

[Display omitted] In these days of information overload and high-throughput analysis, it is easy to lose focus on the study of individual proteins. It is our conjecture that such investigations are still crucially important and offer uniquely penetrative insights. We thus present a discussion of biophysical methods to allow readers to get to know their protein of interest better. Although this perspective is not written with the expert in mind, we hope that for interdisciplinary scientists, or researchers who do not routinely perform biophysical analyses, the content will be helpful and inspiring. [ABSTRACT FROM AUTHOR]

Mixed Reality (MR), based on the seamless blending of the physical and virtual worlds, has demonstrated significant potential in the AECO industry. On-site applications of MR have begun to emerge and are increasingly prevalent. However, there remains a lack of systematic understanding of the field applications of MR in the AECO industry. Therefore, this paper aims to synthesize related studies to analyze and clarify the inherent requirements, challenges, and future directions of using MR. Following the PRISMA, this paper screens and includes relevant studies, combines the interdisciplinary research method, and summarizes the demand for technology use. Then the unique challenges in the AECO industry during the preparation, construction, and operation phases are analyzed. This paper provides a clear understanding of the applications of MR and serves as a valuable reference for future research. • Summary of user requirements for field applications of MR technology. • Overview of the scenarios where MR technology is applied in the field. • Identification of challenges in using MR on-site across various stages of the AECO industry. [ABSTRACT FROM AUTHOR]

This paper investigates the mechanics of the Extrusion Blow Moulding (EBM) process, focusing on the clamp and inflation phases. The simulation framework employed in this study has been developed using OpenFOAM ® and extends the available Finite Area Method with a vertex-centred approach. This cutting-edge developments integrated a corotational formulation with a quasi-static approximation. The computational code and algorithm are verified and validated through comparisons between analytical solutions, experimental measurements and simulation results, ensuring the accuracy and reliability of the proposed approach. The implemented code is verified by checking fundamental principles of hyperelastic materials behaviour, demonstrated through equibiaxial deformation of spherical balloons. The use of neo-Hookean and Mooney–Rivlin material models provides crucial insights into material responses under different inflation conditions. The studies begin employing a conceptual mould within the EBM process that allows examining the effects of mould clamping on parison deformation. Then the study extends to analysing a real bottle manufactured via EBM, employing Stereolithography (STL) digitization and thickness mapping to quantify the thickness distribution. The simulation results closely replicates experimental observations, capturing the inherent non-linearity of these process stages, including large deformations and displacements, hyperelasticity and parison-mould contacts. This interdisciplinary research enhances understanding of the EBM process phases and analogous processes, providing valuable insights for plastic manufacturing. It improves the design process for meeting specific requirements and offers guidelines to avoid potential failures. The findings underscore the importance of such studies in advancing sustainable and efficient plastic manufacturing practices, with applications ranging from inflatable structures to EBM processes. • Novel framework for simulating extrusion blow moulding process in OpenFOAM®. • Improved Finite Area Method with vertex-centred arrangement. • A corotational formulation with quasi-static approximation for increased stability. • Capability to model mould clamping and inflation phases of Extrusion Blow Moulding. • Detailed experimental assessment performed in an industrial case study. [ABSTRACT FROM AUTHOR]

This study conducts a comprehensive analysis on the usage of the blockchain technology in clinical trials, based on a curated corpus of 107 scientific articles from the year 2016 through the first quarter of 2024. Utilizing a methodological framework that integrates bibliometric analysis, network analysis, thematic mapping, and latent Dirichlet allocation, the study explores the terrain and prospective developments within this usage based on data analytics. Through a meticulous examination of the analyzed articles, the present study identifies seven key thematic areas, highlighting the diverse applications and interdisciplinary nature of blockchain in clinical trials. Our findings reveal blockchain capability to enhance data management, participant consent processes, as well as overall trial transparency, efficiency, and security. Additionally, the investigation discloses the emerging synergy between blockchain and advanced technologies, such as artificial intelligence and federated learning, proposing innovative directions for improving clinical research methodologies. Our study underscores the collaborative efforts in dealing with the complexities of integrating blockchain into the areas of clinical trials and healthcare, delineating the transformative potential of blockchain technology in revolutionizing these areas by addressing challenges and promoting practices of efficient, secure, and transparent research. The delineated themes and networks of collaboration provide a blueprint for future inquiry, showing the importance of empirical research to narrow the gap between theoretical promise and practical implementation. • It unites blockchain with AI and federated learning for data privacy and transparency. • It reveals international networks advancing blockchain in clinical trials. • It identifies smart contracts and federated learning for secure and efficient trials. • It detects neural networks and data modeling for blockchain in clinical trials.. • It combines blockchain, AI, and expertise to resolve challenges in clinical trials. [ABSTRACT FROM AUTHOR]

In a recent article, research on clinician responses to emotions and patient ratings of communication is presented. In the discussion section, the authors refer to results from a multidisciplinary research team including the authors of this correspondence. The results of both studies differ in some respects: A closer look at the methodology and the results could help to better understand these different results. [ABSTRACT FROM AUTHOR]

With the exception of the most recent years following the global pandemic, hospitality and tourism-related research specifically examining worker safety, health, and well-being has not been a topic at the forefront in the discipline. Pre-pandemic studies investigating worker well-being frequently used dependent variables such as job satisfaction, turnover intention, and organizational commitment as proxies. The purpose of this research was to identify the gaps in occupational safety, health, and well-being priorities within the contemporary hospitality and tourism and adjacent literature. Utilizing a content analysis of 531 academic journal articles reduced from 4170 originally mined, 11,109 coded segments formed 9 clusters in which 3 overarching themes emerged. Based on the emergent themes, an interdisciplinary research framework adapted from Sorensen et al. (2016) and Peters et al. (2020) is proposed to improve the design and inclusion of occupational safety, health, and well-being constructs in future hospitality and tourism management research. [Display omitted] • This study reviewed 531 academic journal articles regarding worker safety, health, and well-being. • A content analysis methodology was employed, resulting in 11,109 coded segments. • Results revealed that dependent variables focused on job satisfaction, organizational commitment, and turnover. • An agenda is proposed for interdisciplinary research highlighting contextual and workplace factors. • Temporal and multi-level considerations are recommended to leverage interdisciplinary research. [ABSTRACT FROM AUTHOR]

This paper describes how lived experience research, a qualitative research method based on phenomenology, can be modified and incorporated into interdisciplinary environmental risk communication projects. Lived experience methods can give insight into stakeholders' needs and concerns, enabling development of better communication products and potentially helping overcome disciplinary barriers on project teams. We describe the purposes and methods of lived experience research, draw upon two cases from our own experiences to outline how methods can be adapted for the contexts of interdisciplinary research projects, and describe potential barriers to and opportunities for using this research method in team communication projects, including co-production of knowledge, internal research team acceptance, and making project products more responsive to user needs. • A phenomenologically-inspired Lived Experience research method is described. • We pose two cases modifying the method for interdisciplinary science communication. • Effects of modifying interview, analysis, and reporting methods are discussed. • Knowledge co-production and product tailoring to user needs are discussed. • Obstacles for internal research team acceptance are addressed. [ABSTRACT FROM AUTHOR]

• The environmental impacts of a reusable packaging system depend on material, system, and human factors. • People need to be willing to reuse packaging containers more times than the environmental break-even point. • Lightweighting of containers whilst retaining durability and renewable energy for washing can reduce the break-even point. • Return systems (business owned containers) require the return rate to be greater than the break-even point. • Interdisciplinary research is essential to design viable reuse systems. Reuse packaging systems (both return and refill) are a key part of achieving a circular economy, however adoption and uptake are low. A reuse system must be environmentally beneficial, economically viable and acceptable to users such that they are willing to use, and reuse, the system. Here we focus on returnable takeaway food containers and develop a methodology that combines simulating wear associated with use, assessments of consumer willingness to reuse worn containers, and quantitative life cycle assessment (LCA). The findings suggest that environmental break-even points may be lower than the number of times people are willing to use a worn container. Factors such as the design of containers and washing can be improved through lightweighting and use of renewable energy, and behavioural interventions can be delivered to increase willingness. Such interdisciplinary research enables careful system design to ensure that reuse systems confer environmental benefit. [Display omitted] [ABSTRACT FROM AUTHOR]

The gains of sustainability-oriented interventions are threatened by the existence of so-called rebound effects (RE), i.e., higher-order effects of interventions arising due to systemic responses which partially or completely offset potential sustainability gains. While the number of theoretical and empirical studies exploring RE has proliferated, the literature remains highly fragmented and disordered. This paper aims to consolidate and systematize the body of empirical RE studies in its entirety to connect the disjointed literature and shed light on existing research gaps for the identification of future research avenues. Through a systematic literature review, six critical points are identified: (1) an under-exploration of certain RE (i.e., RE outside of direct and economy-wide RE initiated by (energy) efficiency at the household- and macroeconomic production-level); (2) uneven distribution of explored RE mechanisms (i.e., a narrow focus on monetary re-spending effects); (3) a lack of studies exploring the interrelatedness and interdependence of RE mechanisms; (4) a strong emphasis on generalized mechanisms and an underemphasis on context-dependent RE; (5) comparability problems associated with unharmonized RE magnitude estimation techniques and heterogeneity of RE cases; and (6) ambiguity surrounding RE definitions impeding interdisciplinary research. Finally, three research avenues for future research are proposed. [ABSTRACT FROM AUTHOR]

Electrochemical reactions play a critical role in the electrochemiluminescence (ECL) process, serving as the rate-determing steps. Electrocatalysis (EC) is a powerful approach to accelerate electron transfer rates and promote electrochemical reactions, thereby improving ECL properties. With the increasing applications of EC in ECL, how the EC affect the ECL performance have attracted increasing attentions. Understanding the strategies and mechanisms of EC regulation to enhance ECL properties can facilitate the effective application of EC in the ECL field, and promote rational design of EC-mediated ECL systems. This review provides a concise overview of the recent advancements in catalyst-class-dependent EC-based ECL, elucidating the mechanisms of different electrocatalysts in ECL systems. Additionally, we envisage the challenges and unresolved issues in this area. With the advancement of EC technology and interdisciplinary research, EC-based ECL has garnered significant attention and is poised to remain a vibrant field in the years ahead. [Display omitted] • Electrocatalysis is an efficient approach to enhance the ECL properties. • Summarizes the recent progress of catalyst-class-dependent electrocatalysis -based ECL. • Elucidates the mechanisms and sensing strategies of different electrocatalysts in ECL systems. • Discusses the remaining challenges and unresolved issues in electrocatalysis -based ECL area. [ABSTRACT FROM AUTHOR]

Affective computing is an increasing interdisciplinary research field that provides great potential to recognize, understand and express human emotions. Recently, multimodal analysis starts to gain more popularity in affective studies, which could provide a more comprehensive view of emotion dynamics based on the diverse and complementary information from different data modalities. However, the stability and generalizability of current multimodal analysis methods have not been thoroughly developed yet. In this paper, we propose a novel multimodal analysis method (EEG-AVE : EEG with audio-visual embedding) for cross-individual affective detection, where EEG signals are exploited to identify the emotion-related individual preferences and audio-visual information is leveraged to estimate the intrinsic emotions involved in the multimedia content. EEG-AVE is composed of two main modules. For EEG-based individual preferences prediction module, a multi-scale domain adversarial neural network is developed to explore the shared dynamic, informative, and domain-invariant EEG features across individuals. For video-based intrinsic emotions estimation module, a deep audio-visual feature-based hypergraph clustering method is proposed to examine the latent relationship between semantic audio-visual features and emotions. Through an embedding model, both estimated individual preferences and intrinsic emotions are incorporated with shared weights and further contribute to affective detection across individuals. Experiments on two well-known emotional databases indicate that the proposed EEG-AVE model achieves a better performance under a leave-one-individual-out cross-validation individual-independent evaluation protocol. The results demonstrate that EEG-AVE is an effective model with good reliability and generalizability, which has practical significance in the development of multimodal analysis in affective computing. [ABSTRACT FROM AUTHOR]

In this paper, we argue that understanding and addressing the problem of poor-quality medical products requires a more interdisciplinary approach than has been evident to date. While prospective studies based on rigorous standardized methodologies are the gold standard for measuring the prevalence of poor-quality medical products and understanding their distribution nationally and internationally, they should be complemented by social science research to unpack the complex set of social, economic, and governance factors that underlie these patterns. In the following sections, we discuss specific examples of prospective quality surveys and of social science studies, highlighting the value of cross-sector partnerships in driving high-quality, policy-relevant research in this area. [ABSTRACT FROM AUTHOR]

In the Cluster of Excellence "Matters of Activity", researchers from humanities, design, natural and social sciences, and medicine work together, producing diverse outcomes which all are relevant for reporting to the funding agencies and society. Here, we describe the development of a researcher-oriented CRIS embracing not only text publications but also other research outcomes on equal footing. We illustrate the flexibility of the system by introducing a new output category Research Prototypes. We discuss the challenges and benefits of a local CRIS solution for a small, non-permanent organization, in which researchers from several organizations are working on specific research topics. [ABSTRACT FROM AUTHOR]

• Globally, primary care (PC) has seen significant disruptions and strain from the COVID-19 pandemic, jeopardizing the ability to provide safe, accessible in-person care. • Our "action research" team from the high-income country (HIC) context of Alberta, Canada, developed an innovative virtual tabletop simulation (TTS) intervention which assisted clinical teams to deliver safe, in-person care during the COVID-19 pandemic. • We examine "adaptive elements" which contributed to our program's success, which were just as important as the technical details of virtual TTS program implementation. • Rather than assuming this innovation developed in a HIC setting should be used to solve low- and middle-income country (LMIC) challenges, we ask whether and how our virtual TTS intervention might be adapted in other settings to improve the safety and accessibility of PC during the COVID-19 pandemic. Globally, primary care (PC) has been central to the COVID-19 response. The pandemic has strained PC systems and introduced novel infection prevention and control (IPC) risks to the provision of safe, accessible in-person care. Specifically, the implementation of IPC guidance developed outside of PC into its operational context has proved challenging. Our team of "action researchers" developed an innovative virtual tabletop simulations (TTS) intervention which assisted PC teams as they adapted, implemented, and integrated IPC guidance into their specific clinical contexts. While we have detailed the "technical" elements of the TTS program elsewhere, this paper examines the specific "adaptive" elements that made this intervention successful in the high-income country context of Alberta, Canada. Multiple factors influenced the uptake of this program in our Albertan setting, including: cultural geography; approach to financing and delivering PC; and policies and cultural norms supporting PC integration, medical education and research, and egalitarian teamwork. Virtual TTS may provide substantial benefits to IPC and safety improvements in PC settings globally. However, the specific technical and adaptive elements of our Albertan TTS program might, or might not, make these a viable IPC intervention for adapting, spreading, and scaling to other settings. [ABSTRACT FROM AUTHOR]

Objective: Some students may face challenges with graduate-level reading and writing, particularly in certain active learning pedagogies, such as team-based learning or peer instruction, which require extensive pre-reading. The objective of this study is to determine the perceived utility of an academic literacy (reading/writing) test for first professional year student pharmacists (P1s).Methods: In a collaboration between pharmacy and linguistics faculty, an academic literacy assessment tool was developed using fall P1 course materials. After pilot testing and adjustments, the revised test was administered to all P1 students by trained facilitators, then scored. Students needing literacy support were identified, met with individually to debrief on the assessment, and offered a year-long, one-on-one tutoring program. P1 faculty participated in an end-of-semester focus group session to determine whether the assessment correctly identified students who benefited from literacy support, and to decide on the impact of subsequent support. Thematic analysis was performed on the data.Results: A total of 13 students were identified as at-risk through the assessment. Since tutoring was optional, eight students met at least once, and two students met weekly during the ensuing semester. Faculty from the end-of-semester focus group 1) stated that the assessment accurately pre-identified students who struggled with literacy components of P1 coursework, and 2) expressed a wish for earlier identification of students with required instead of optional tutoring.Conclusions: Faculty perceived that the tool accurately identified students, but the timing and the volunteer nature of the follow-up tutoring limited the success of the assessment effort. [ABSTRACT FROM AUTHOR]

• Forensic anthropology is important for medico-legal death investigations. • Value and merit of interdisciplinary knowledge and a collaborative approach to forensic casework. • Need for national regulatory framework for the practice of forensic anthropology in South Africa. Forensic anthropology in South Africa is well developed in the higher education sector, with advanced training and research programmes. Despite this and decades of academic involvement in casework, forensic anthropology still lacks a defined framework and mandate at a governmental level. Therefore, the involvement of forensic anthropologists' expertise varies markedly between cases, provinces, and among various stakeholders within the country, to the detriment of dispensation of social and criminal justice. The lack of clearly defined guidelines for the rendering of the service was exemplified and demonstrated through a recent forensic case. Here, contextual information was absent, and the remains posed a challenge to analyse, ostensibly due to missing information. Numerous questions were raised during the analysis of the remains, and broader concerns about the investigative involvement of a forensic anthropologist within South African casework were brought to the fore. Through the analysis of this case, we describe the deductive processes that led to the formation of an opinion that the skeletal linear defects were the result of taphonomic changes. In addition, we highlight how these efforts where constrained and each step in the process unnecessarily hindered. Finally, we demonstrate the capacity and willingness of forensic anthropology practitioners to be involved, and how, without governmental support, it is a great potential lamentably untapped. [ABSTRACT FROM AUTHOR]

Research suggests that traditional Chinese medicine (TCM) holds promise in offering innovative approaches to tackle neurodegenerative disorders. In our endeavor, we conducted a comprehensive bibliometric analysis to delve into the landscape of TCM research within the realm of neurodegenerative diseases, aiming to uncover the present scenario, breadth, and trends in this field. This analysis presents potentially valuable insights for the clinical application of traditional Chinese medicine and provides compelling evidence supporting its efficacy in the treatment of neurodegenerative conditions. The incidence of neurodegenerative diseases is on the rise, yet effective treatments are still lacking. Research indicates that TCM could offer novel perspectives for addressing neurodegenerative conditions. Nonetheless, the literature on this topic is intricate and multifaceted, with existing reviews offering only limited coverage. To gain a thorough understanding of TCM research in neurodegenerative diseases, we undertook a bibliometric analysis to explore the current status, scope, and trends in this area. A literature search was carried out on April 1, 2024, utilizing the Web of Science Core Collection (WoSCC). Visualization and quantitative analyses were then performed with the assistance of CiteSpace, VOSviewer, and R software. A total of 6856 articles were retrieved in the search. Research on TCM for neurodegenerative diseases commenced in 1989 and has exhibited a notable overall growth since then. Main research contributors include East Asian countries like China, as well as the United States. Through our analysis, we identified 15 highly productive authors, 10 top-tier journals, 13 citation clusters, 11 influential articles, and observed a progression in keyword evolution across 4 distinct categories. In 2020, there was a significant upsurge in the knowledge base, collaboration efforts, and publication output within the field. This field is interdisciplinary: network pharmacology emerges as the cutting-edge paradigm in TCM research, while Alzheimer's disease remains a prominent focus among neurodegenerative conditions due to its evolving etiology. A burst detection analysis unveils that in 2024, the focal points of research convergence between TCM and neurodegenerative diseases lie in two key biological processes or mechanisms: autophagy and microbiota. For the first time, this study quantitatively and visually captures the evolution of TCM in addressing neurodegenerative diseases, showcasing a notable acceleration in recent years. Our findings underscore the pivotal role of interdisciplinary collaboration and the necessity for increased global partnerships. Network pharmacology, leveraging the advancements of the big data era, embraces a holistic and systematic approach as a novel paradigm in exploring traditional Chinese medicine and unraveling their fundamental mechanisms. Three ethnomedical plants—Tianma, Renshen, and Wuweizi—demonstrate the promise of their bioactive compounds in treating neurodegenerative disorders, bolstered by their extensive historical usage for such ailments. Moreover, our intricate analysis of the evolutionary trajectories of key themes such as targets and biomarkers substantially enriches our comprehension of the underlying mechanisms involved. [Display omitted] [ABSTRACT FROM AUTHOR]

The many human interactions within cities inevitably generate relations between different places, civic and political organisations, authorities, and eventually conflictual events. Among all conflicts occurring in urban environments, if some are isolated events, many are connected by strong dependencies that generate networks in space and time. The research presented in this paper introduces a graph-based approach whose objective is to track the intertwined relations and dependencies that are associated with registered conflicts. The approach is experimented with and implemented using a combination of a graph-based database and visual graphics that together provide a series of data query capabilities and analysis specifically adapted to the context of our study. An experimental application to a series of conflicts reported in local media from 1985 to 2007 in the urban area of Montréal in Canada is presented and discussed. • This paper presents original research analyzing conflicts in a large urban area, integrating semantic, spatial, and temporal dimensions through a robust modeling approach. • It introduces a novel graph-based database that models urban conflicts in space and time and whose network modelling concepts support the tracking of all conflicts and associated information in space and time. • The approach is applied to a comprehensive datasets of conflicts extracted from daily newspapers in the city of Montréal, providingseveral database queries and visualizations that demonstrate the potential of the approach for analysing spatio-temporal events. • This multidisciplinary research combines computer and geographical sciences, offering a holistic perspective on urban conflict analysis [ABSTRACT FROM AUTHOR]

The design of real-world engineering systems deals with high complexity at the system and subsystem levels, as well as the interaction between the subsystems involved. Multidisciplinary Design Optimization (MDO), which aims to integrate the optimization algorithms in both system and subsystem levels along with exploring mechanisms of synergistic action among subsystems, is a renowned methodology to design complex engineering systems. In Multi-Agent Systems (MASs), as a complex system, to achieve the best system performance, agents have to work their individual tasks in a coordinated manner and in cooperation with other agents. Given some architectural resemblance between MDO and MAS, especially in subsystems interaction (agents, in MAS case), this paper addresses proposing a multi-agent multidisciplinary system design optimization strategy. This strategy by taking advantage of the capabilities of MDO proposes a consolidated framework for the optimal design of real world engineering systems. This strategy is extendable to multi-agent systems in a diverse range of missions and tasks. In this regard to illustrating its application a distributed cooperative search and coverage (CSC) mission in uncertain environments is considered as a case study for designing a MAS. The proposed framework contributes to designing a MAS by applying the history data of previously completed missions and the normalized cross-correlating (NCC) algorithm as well. The effectiveness of the proposed framework is demonstrated via simulations and comparison. [ABSTRACT FROM AUTHOR]

The sound speed profile (SSP) is an important factor affecting the acoustic propagation characteristics of the ocean, making the accurate acquisition of SSP a crucial step in the interdisciplinary research of oceanography and underwater acoustics. Limited by the cost of in-situ measurement and the performance of the instrument itself, direct measurement of SSP inevitably leads to insufficient depth or even missing information. In this paper, we propose using partial underwater prior information (UWPI) only including underwater sound speed to obtain preliminary reconstruction results of global SSP for the first time. The empirical orthogonal function (EOF) reconstruction algorithm is optimized by employing assimilated SSP as the background SSP to further reduce reconstruction errors. The maximum global average reconstruction error and root mean square error (RMSE) after optimization decrease by >51% and 71%, respectively, which indicates that the performance of the optimized algorithm combined with partial UWPI is further improved. Finally, the performance of the optimized algorithm is discussed from the perspective of acoustic propagation. This research provides a reliable technical approach for SSP reconstruction under incomplete depth conditions, which can be applied in underwater sound field prediction and acoustic detection in the future. [Display omitted] • Global scale SSP large-depth fast reconstruction is realized based on partial UWPI for the first time. • The algorithm is optimized and the maximum reconstruction error and RMSE decrease by >51% and 71%, respectively. • Providing a reliable technical approach for SSP reconstruction under incomplete depth conditions. [ABSTRACT FROM AUTHOR]

• We develop two novel measures of citation scope using geography and research field as metrics and explore their mediating effects on scholarly impact. • We retrieve two different time periods of accrued citations to explore the temporary effects of influencing factors for highly cited research. • Our finding sheds some light on the mechanism by which internationally collaborative research and interdisciplinary studies positively affect research visibility. The highly skewed nature of research influence has been widely acknowledged. Among extant studies examining contributing factors, most focus on the hard sciences in developed economies with very few examining the social sciences in emerging powers. The impact of citation scope is likewise left largely underexplored. In this paper, we develop two novel measures of citation scope using geography and research field as metrics and explore their role in boosting academic impact. Our results support geography as a citation scope serving an important pathway through which international collaboration affects academic impact. Such effect increases in prominence in later years. We do not find evidence indicating the mediating effect of research field citation scope on scholarly recognition. [ABSTRACT FROM AUTHOR]

This paper addresses the limited research on the metaverse's application in the construction industry. It aims to investigate how the metaverse can empower construction, identify adoption barriers, and determine the most significant barriers. We propose a novel application framework of construction metaverse based on cyber-physical-social systems, identify 17 barriers using the political-economic-social-technological framework, and employ an expert survey and bi-objective optimization to rank the barriers. Results indicate that scalability, lack of policy incentives, and immature business models are the most critical barriers. The findings provide valuable insights for researchers, practitioners, and policymakers in the construction industry, helping to allocate resources effectively and drive metaverse development. The study's importance lies in its potential to guide successful metaverse integration in construction, leading to improved efficiency and innovation. This research inspires future work on specific metaverse applications in construction and interdisciplinary research to understand and overcome the identified barriers. • We propose a CPSS-based framework for construction metaverse. • We identify the barriers that hinder the construction metaverse application. • We evaluate critical levels of identified barriers. [ABSTRACT FROM AUTHOR]

The six papers included in this special issue represent a selection of extended contributions presented at the 17th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2022 held in Salamanca, Spain, September 6th-8th, 2022, and organized by the BISITE group at the University of Salamanca. The International Conference on Hybrid Artificial Intelligence Systems (HAIS 2022) has become a unique, established, and broad interdisciplinary forum for researchers and practitioners who are involved in developing and applying symbolic and sub-symbolic techniques aimed at the construction of highly robust and reliable problem-solving techniques to present the most relevant achievements in this field. HAIS Series of Conferences provides an interesting opportunity to present and discuss the latest theoretical advances and real-world applications in this multidisciplinary research field. [ABSTRACT FROM AUTHOR]

Nanoscale lattices formed through the art of controlled self-assembly hold a promise for the creation of advanced materials with diverse applications. These versatile particles, boasting exceptional attributes such as colloidal stability, tunable sizes, and an array of sophisticated shapes, allow access to a vast multifunctionality. In this context, the controlled self-assembly of colloidal metal-organic framework (MOF) particles is a promising field that encourage scientists to continue exploring across the limits of what is possible. A thorough investigation of this new field of study reveals the possibility of influencing a future in which innovation and creativity converge to produce a wide range of applications. In this review, we present a comprehensive overview of the self-assembly of colloidal MOF (CMOF) particles into ordered superstructures, with a focus on the underlying principles governing the self-assembly of CMOF, design and synthetic strategies, as well as their self-assembly mechanisms. In addition, the stability of CMOF particles is highlighted, emphasizing efforts and strategies to ensure their reliability. Finally, we offer some insights and perspectives for the future development and the potential application of CMOF, reflecting the great potential and rapid development of this interdisciplinary research field. We aim to provide new insights into MOF particle self-assembly and further guide future research for large-scale applications. [Display omitted] [ABSTRACT FROM AUTHOR]

Understanding black box models has become paramount as systems based on opaque Artificial Intelligence (AI) continue to flourish in diverse real-world applications. In response, Explainable AI (XAI) has emerged as a field of research with practical and ethical benefits across various domains. This paper highlights the advancements in XAI and its application in real-world scenarios and addresses the ongoing challenges within XAI, emphasizing the need for broader perspectives and collaborative efforts. We bring together experts from diverse fields to identify open problems, striving to synchronize research agendas and accelerate XAI in practical applications. By fostering collaborative discussion and interdisciplinary cooperation, we aim to propel XAI forward, contributing to its continued success. We aim to develop a comprehensive proposal for advancing XAI. To achieve this goal, we present a manifesto of 28 open problems categorized into nine categories. These challenges encapsulate the complexities and nuances of XAI and offer a road map for future research. For each problem, we provide promising research directions in the hope of harnessing the collective intelligence of interested stakeholders. [ABSTRACT FROM AUTHOR]

• Sociomaterialities of extractivism rush and resist the making of resource frontiers. • Communities resist coercive extractivism to defend socionatural multiplicities. • Activism at times disrupts extractivism and at others altogether unmake resources. • Resistance we unearth in Maidan is a process of unmaking gold as a resource. • Maidan's struggle is an institutional experimentation for shaping just socionatures. In October 2013, around 200 protestors from the rural settlement Maidan in Kyrgyzstan clashed violently with the representatives of the exploration company as they brought in the first excavator to construct the mining infrastructure for the 'Shambesai' gold deposit. This paper is an attempt to understand the processes and practices that have led to this escalation and that continue to sustain Maidan's rejection of the gold mine to date. Motivated by state and corporate assertions that attribute such actions primarily to material interests, we engage this resistance to gold extractivism in sociomaterial terms trying to understand more deeply the dynamics of ordinary citizens' activism. Based on multi-stage interdisciplinary research, we trace and reconstruct the socionatural conditions and practices that have culminated in Maidan's decade-long struggle to unmake gold as a resource on their territory. Focusing on resource materialities, their valuations and governance, we present an historico-geographical analysis of making and unmaking of a resource frontier. Against the backdrop of the extractive order that has prevailed in Kyrgyzstan over the last three decades, we understand Maidan's struggle to be a form of situated institutional experimentation for shaping meaningful and just more-than-human socionatures. [ABSTRACT FROM AUTHOR]

Addressing complex environmental and health questions requires research collaborations. Such collaborations harness diverse expertise and perspectives from various researchers, practitioners, stakeholders, and knowledge-users to ground and enhance the depth and breadth of research and promote translational efforts towards policymaking. There is growing interest and need to understand what shapes these partnerships. Thus, our objective was to empirically identify the essential components of a collaborative research process. This qualitative case study followed a complex interdisciplinary research project over five years of operation. The project utilized an Integrated Knowledge Translation approach (IKT), a research partnership between researchers and knowledge-users. Data were generated through experiential interview/focus groups, surveys, and participant observation analyzed using inductive thematic analysis procedures. We identified eight essential components. The partnership evolved by building relationships , advancing individual growth , and building team capacity. These require the alignment of progress, knowledge, and expectations, establishing trust in each other, procedures, and outcomes, and developing shared ownership. Furthermore, operative elements and individual attitudes fostered the collaborative climate evolution. All components contributed directly and indirectly through complex interactions to shaping and maintaining the collaborative process and ultimately to growth, performance, co-production, and translational initiatives. At different times, the attainment or absence of these components facilitated or hindered the project's progression. This study provides an empiric in-depth description of the evolution of individual and collaborative team processes in which interdisciplinarity and IKT fostered co-production and knowledge translation. The evidence can serve as focal points to guide future planning and operation of research partnerships in different contexts. [Display omitted] • A qualitative case study exploring team processes in collaborative research. • Eight components were essential for a successful research collaboration process. • The components included dynamic team processes and enabling conditions. • All components jointly evolved to reach optimal performance and productivity. • Our empiric findings could serve as focal points for other research collaborations. [ABSTRACT FROM AUTHOR]

Si « manger » peut être perçu comme un acte trivial, l'acte de manger est en fait l'expression de notre identité (culturelle) et le « baromètre » de notre bien-être et de notre santé. À la fois multidimensionnel, dynamique et interactionnel, l'acte de manger devient un véritable enjeu pour certains profils de mangeurs [dits à risque de troubles des conduites alimentaires (TCA)] ; et ce, particulièrement en contexte pandémique [48]. Par conséquent, sa compréhension holistique et sa régulation complexe visant la protection des populations imposent une approche en transdisciplinarité ou transdisciplinaire ; idéalement dans un prisme intersectoriel [44,51]. Pourtant la société, dans le domaine de la santé, approche les troubles des conduites alimentaires et l'obésité comme l'expression de l'acte de manger, et ce, en silo par des interventions multidisciplinaires ou au mieux interdisciplinaires [11]. En multidisciplinarité, les disciplines sont positionnées comme étant indépendantes les unes des autres. Chaque intervenant propose l'évaluation et le plan d'intervention issus de sa discipline propre. L'individu est alors, tour à tour, un patient, un client et un usager composé de différentes parties mais sans représenter un tout [11]. En interdisciplinarité, les disciplines sont positionnées comme étant complémentaires les unes aux autres par l'entremise d'un « coordonnateur disciplinaire ». En concertation avec chaque intervenant, le coordonnateur veille à ce que l'évaluation et le plan d'intervention issus de sa discipline répondent à un objectif commun. L'individu est la résultante d'une combinaison d'un patient, d'un client et d'un usager qui tente de représenter un tout [43]. Le constat est clair : ces interventions multi- et inter-disciplinaires en santé ne suffisent pas à répondre à la complexité des enjeux relatifs à l'acte de manger puisque (i) 60 % des individus sont au mieux rétablis, (ii) 50 % des individus présentent toujours des attitudes et des comportements alimentaires dysfonctionnels dix à vingt ans après les interventions et (iii) un individu décède toutes les 52 minutes de complications relatives aux troubles des conduites alimentaires et à l'obésité [18,25,50]. La question se pose : une intervention transdisciplinaire, selon une visée holistique de l'individu basée sur l'intégration des disciplines, serait-elle à considérer pour pallier ces enjeux sociétaux ? "Eating" might be perceived as trivial but the act of eating is, in fact, the expression of our (cultural) identity and the "barometer" of our well-being and health. Multidimensional, dynamic and interactional, the act of eating becomes a real issue for certain profiles of eaters [said to be at risk of eating disorders (ED)]; and this is particularly true in the context of a pandemic [48]. Consequently, its holistic understanding and its complex management aiming for the protection of populations impose a transdisciplinary approach; ideally in an intersectoral prism [44,51]. However, society, in the field of health, approaches eating disorders and obesity as an expression of the act of eating, in silo with multidisciplinary or, at best, interdisciplinary (silo-based) interventions [11]. In the multidisciplinary approach, the disciplines are positioned as independent of each other. Each practitioner proposes an assessment and an intervention plan based on his or her own discipline. The individual is then seen as a patient, a client and a user made up of different parts but without representing a whole [11]. In the interdisciplinary approach, the disciplines are positioned as complementary to each other through a "disciplinary coordinator". In consultation with each practitioner, the coordinator ensures that the assessment and intervention plan from his or her discipline meets a common objective. The individual is the result of a combination of a patient, a client and a user who attempts to represent a whole [43]. It is clear that these multi- and inter-disciplinary health interventions are not sufficient to respond to the complexity of the issues related to the act of eating since (i) 60% of individuals recover, at best, (ii) 50% of individuals still have dysfunctional eating attitudes and behaviors 10 to 20 years after the interventions and (iii) one individual dies every 52 minutes from complications related to eating disorders and obesity [18,25,50]. A question arises: should a transdisciplinary intervention with a holistic view of the individual based on the integration of disciplines be considered to address these societal issues? [ABSTRACT FROM AUTHOR]

Hayes et al. (2021) provide a variety of valuable recommendations for contextual behavioral scientists to increase the impact of their research. The merits and weaknesses of these recommendations are discussed from pragmatic and theoretical perspectives. Our commentary on the positive and negative facets of the Task Force findings are informed by our extensive experience working with underrepresented communities and as scholars of color ourselves. While we agree that improving psychological science will require an interdisciplinary approach, we highlight how this white paper is not entirely accessible to diverse samples and scientists alike, and thus, may limit interdisciplinary partnerships. Moreover, further bolstering is needed related to equity, diversity, and inclusion to ensure that future CBS research can fulfill its highly prosocial and innovative mission. Lessons learned from our own work and other diversity science scholars in the field are provided in order to highlight potential future directions for CBS scholars to consider to strengthen the applicability of the Task Force recommendations across diverse samples. • Many laudable prosocial recommendations are made by the ACBS Task Force on Contextual Behavioral Science • More attention is needed to make the recommendations more applicable to diverse community samples and diverse scholars • Stronger emphasis on interdisciplinary partnerships within the community and academic networks would bolster success and impact of CBS • Other perspectives on how CBS may leverage existing work conducted via CBPR, IS, and social justice are presented [ABSTRACT FROM AUTHOR]

The understanding of environmental observations is a continuous challenge for environmental and life science investigations. The environmental data is complex as it involves its own features, methods, properties, systems, and spatio-temporal dimensions. The time granularity remains approximately the same for different environmental contexts but geographic and rest of the above-mentioned entities are defined using domain vocabularies that are specific for each discipline. It is time-consuming for the researchers of life sciences' discipline to discover, access, and analyze relevant environmental observations as each discipline has its data formats, vocabularies, and metadata standards. These differences introduce structural and semantic heterogeneities, resulting in creating a barrier for reusing datasets generated by other disciplines. Existing dataset discovery platforms contain domain-specific metadata descriptions for explaining datasets which limits their usage. To overcome this knowledge barrier, this work reports the proof-of-concept implementation of a knowledge graph that is centered towards the oceanography use case scenario using NLP techniques (named entity recognition (NER) followed by text preprocessing). The constructed knowledge graph is a collection of subgraphs each representing the metadata of a dataset. It uses the geo-spatial and open semantic data standards that aim to provide enhanced metadata descriptions of datasets for enabling multidisciplinary research. [ABSTRACT FROM AUTHOR]