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• Water retention curves (WRCs) of municipal solid wastes (MSWs) • Hysteresis of WRCs of MSWs with decomposition. • Effects of decomposition and paper content on the WRCs. • Unsaturated hydraulic and gas conductivity of MSWs. This paper investigates the drying and wetting water retention curves (WRCs) of municipal solid wastes (MSWs) with different paper contents, dry unit weights and degrees of biodegradation (DOBs). Fresh synthetic samples were prepared based on the field composition of the MSWs at Mugga Lane Landfill, the Australian Capital Territory (ACT), Australia. The degraded samples were prepared in simulators with MSWs of different initial dry unit weights and decomposition periods with leachate recirculation. The water retention curves (WRCs) of the MSWs were determined using pressure plate tests, in both drying and wetting phases. The outflow from MSWs was analysed using Gardner's method to obtain the unsaturated hydraulic conductivity. The results indicate that the WRCs of the MSWs are greatly affected by the DOB, paper content and dry unit weight. When DOB < 30 %, as DOB increases, the air-entry pressure of MSWs with paper increases, and the residual moisture content decreases regardless of paper content. With DOB > 30 %, the air entry pressure and residual water content depend on the balance between organic matter and highly decomposed organic constituents. The paper content affects the WRCs of MSWs due to its water retention capacity and change in the particle size distribution with decomposition. The increase in the dry unit weight of MSWs significantly increases the air entry pressure and residual moisture content, similar to the borehole samples with combined effects of biodegradation and increase in stress level from literature. Hysteresis effects have been observed during the drying and wetting of MSWs. The hysteresis of WRCs increases with the paper content and DOB. [ABSTRACT FROM AUTHOR]

Portfolios are used in midwifery education to provide students with a central place to store their accumulative evidence of clinical experience for initial registration in Australia. Portfolio formats can be paper-based or electronic. Anecdotal discussion between midwifery students in Queensland debated the best format to document the requirements for the Australian Nursing and Midwifery Accreditation Council (ANMAC) standard 8.11. Midwifery students using paper-based portfolios envisioned that an ePortfolio would be streamline, simple, safe to use, and able to be used anywhere with WIFI, while some students using an ePortfolio expressed a desire to have a paper-based portfolio as a hard copy. This situation called for evidence of a comparison to resolve the debate. The aim of this study was to investigate midwifery students' experiences of the benefits and challenges between paper-based and ePortfolios when compiling evidence to meet the requirements for initial registration as a midwife in Australia (ANMAC, 2014). • Each type of portfolio had challenges and benefits. • Portfolio completion is time consuming, and stressful due to the need for verification of evidence. • Students require early and regular feedback on portfolio development. • National standards are required for consistency in documentation across universities. [ABSTRACT FROM AUTHOR]

This discussion paper highlights the importance of Australian nursing and midwifery students' lack of exposure to electronic medical records during their undergraduate programs. There is pressure on universities offering nursing and midwifery programs to provide students with opportunities to learn to use patient electronic medical records. This will provide authentic rehearsal with the digital technology prior to clinical placements and increase graduate work readiness. Informed by contemporary literature, we describe the benefits of implementing electronic medical records (eMR) in health organisations and identify the challenges and barriers to implementing and integrating the education of electronic records into undergraduate nursing and midwifery programs. Undergraduate students who had not experienced eMR as part of on-campus learning felt unprepared and lacked confidence when commencing clinical practice. Some international nursing and midwifery programs have found that student's skills improve in decision-making and documenting patient observations when eMR is integrated into their university education program. Successful integration of an eMR program should consider academic/teaching staff skills and confidence in technology use, initial and ongoing costs and technical support required to deliver the program. In conclusion, Australian universities need to embed eMR learning experiences into the nursing and midwifery undergraduate curricula to increase students work-readiness with a focus on patient safety. [ABSTRACT FROM AUTHOR]

• First assessment of paper chromatography using large sample sizes and microbe DNA. • Chromatogram features did not vary consistently with gradients of soil condition. • Results imply context dependent response of chromatogram features to soil condition. • Paper chromatography needs more testing before being embraced for soil assessment. Although paper chromatography is being promoted as a cost-effective tool for rapid assessment of soil health, few studies have explored the quantitative relationship between chromatogram features and soil health variables, and no studies have investigated the association between chromatogram features and microbial diversity as determined using DNA sequences. We assessed 343 soil samples from varying land uses in southwestern Australia to investigate the relationship between total organic carbon, microbial activity and diversity, salinity and pH levels and 12 chromatogram features. Spearman's correlations and variance partitioning were used to detect relationships. Although total organic carbon and microbial activity displayed the strongest correlations with chromatogram features, they were not associated with greater development of radial features and median zone radius as expected. This was in contrast to what has been previously reported, implying context dependent responses of chromatogram features to gradients in soil variables. Microbial community structure was found to explain changes in chromatogram features better than the measured soil variables. These results indicate that further studies are necessary before paper chromatography is embraced as a tool for soil health assessment, and raises questions regarding the use of chromatography by community groups as a tool to measure soil health. [ABSTRACT FROM AUTHOR]

Internet surveys are becoming an increasing popular survey collection method because collection times are quicker and survey costs are lower than other collection techniques. Many studies have been conducted overseas to compare the effects of survey collection modes with results still remaining inconsistent. Fewer studies have compared collection methods for nonmarket valuation surveys, particularly for the more complex stated preference, choice modelling surveys. In this study, a comparison of internet and paper-based surveys is made to determine if the results for overseas studies can be replicated in Australia. The valuation exercise elicited values from Brisbane respondents for future improvements in the environmental condition of the Great Barrier Reef. The results indicate that there were some socio-demographic and attitudinal differences between the two samples and the models developed to explain the influence on choice selection were also significantly different. However, no differences in value estimates were found in the final results; household willingness-to-pay for an improvement in the condition of the GBR was equivalent across collection methods. [ABSTRACT FROM AUTHOR]

When undertaking any study of the isotope abundance values of a bulk material, consideration should be given to the source materials and how they are combined to reach the final product being measured. While it is demonstrative to measure and record the values of clean papers, such as the results published as part one of this series, the majority of forensic casework samples would have undergone some form of writing or printing process prior to examination. Understanding the effects of these processes on the δ13C values of paper is essential for interpretation and comparison with clean samples, for example in cases where printed documents need to be compared to paper from an unprinted suspect ream. This study was undertaken so that the source materials, the effects of the production process and the effects of printing and forensic testing could be observed with respect to 80 gsm white office papers. Samples were taken sequentially from the paper production facility at the Australian Paper Mill (Maryvale, VIC). These samples ranged from raw wood chips through the pulping, whitening and refinement steps to the final formed and packed paper. Cellulose was extracted from each sample to observe both fractionation and mixing steps and their effect on the δ13C values. Overall, the mixing steps were observed to have a larger effect on the isotopic values of the bulk materials than any potential fractionation. Printing of papers using toner and inkjet printing processes and forensic testing were observed to have little effect on δ13C. These experiments highlighted considerations for sampling and confirmed the need for a holistic understanding of sample history to inform the interpretation of results. [ABSTRACT FROM AUTHOR]

Staphylococcus argenteus and Staphylococcus schweitzeri, previously known as divergent Staphylococcus aureus clonal lineages, have been recently established as novel, difficult-to-delimit, coagulase-positive species within the S. aureus complex. Methicillin-resistant strains of S. argenteus are known from Australia and the UK. Knowledge of their epidemiology, medical significance and transmission risk is limited and partly contradictory, hampering definitive recommendations. There is mounting evidence that the pathogenicity of S. argenteus is similar to that of 'classical' S. aureus , while as yet no S. schweitzeri infections have been reported. To provide decision support on whether and how to distinguish and report both species. PubMed, searched for S. argenteus and S. schweitzeri. This position paper reviews the main characteristics of both species and draws conclusions for microbiological diagnostics and surveillance as well as infection prevention and control measures. We propose not distinguishing within the S. aureus complex for routine reporting purposes until there is evidence that pathogenicity or clinical outcome differ markedly between the different species. Primarily for research purposes, suitably equipped laboratories are encouraged to differentiate between S. argenteus and S. schweitzeri. Caution is urged if these novel species are explicitly reported. In such cases, a specific comment should be added (i.e. 'member of the S.aureus complex') to prevent confusion with less- or non-pathogenic staphylococci. Prioritizing aspects of patient safety, methicillin-resistant isolates should be handled as recommended for methicillin-resistant Staphylococcus aureus (MRSA). In these cases, the clinician responsible should be directly contacted and informed by the diagnosing microbiological laboratory, as they would be for MRSA. Research is warranted to clarify the epidemiology, clinical impact and implications for infection control of such isolates. [ABSTRACT FROM AUTHOR]

Abstract: In Australia, a pervasive response to increasing atmospheric greenhouse gasses and the exchange of these gasses between the atmosphere and forests has been to focus on storing carbon (C) in forested landscapes. However, the amount of C stored and able to be stored in the landscape, which is often called carbon carrying capacity, is commonly over-estimated and over-emphasised. This occurs, in part, due to a focus on the continent’s most C-rich forests when discussing landscape C storage or carbon carrying capacity, and by failing to account for wildfires that will prevent all forests from becoming old and C-rich. These effects on forest age-class structure and thus C-stocks, in the Australian landscape currently tend to be overlooked at the policy level. Underemphasised is the widely recognised role of wood products in greenhouse gas mitigation, both as a C-stock and by providing society with low emission products. Improving atmospheric outcomes will only be achieved if variation in landscape C stocks is accurately described and the full role of forests in greenhouse gas mitigation including the role of wood products is explored and reflected in policy. [Copyright &y& Elsevier]

Systematic conservation planning (SCP) is a field of conservation biology concerned with the effective allocation of conservation efforts and the implementation of actions aiming to guarantee biodiversity persistence in the long-term and the efficient use of conservation resources. Here, we evaluated the main spatial-temporal trends and patterns among highly-cited papers in SCP. We considered "highly-cited" articles as those papers with at least 100 citations according to Web of Science database. A total of 132 highly-cited articles were published between 1989 and 2014, with the highest frequency at 2006. Papers were published in 25 different scientific journals (with a highlight for Conservation Biology and Biological Conservation) by researchers from 208 institutions and 25 countries (most from Australia and USA). Most of the analytical and methodological studies were carried out in the terrestrial environment, by considering more than one taxonomic group, and at a regional scale. Eleven studies included information on costs (e.g., economic or land use) in the prioritization process, and only one article considered information on other biodiversity dimensions such as phylogenetic diversity. Among analytical papers, 41 included only biodiversity data in the prioritization process, while 16 papers considered data on other features such as ecosystem services, biophysical factors, and vegetation. Furthermore, a plethora of different algorithms and software were used to perform the analyses. By analyzing the top-cited papers, we could track through time the main advances and stages of the development in SCP. [ABSTRACT FROM AUTHOR]

The article focuses on supporting physical education teachers through a web-based education intervention which increases physical activity during physical education classes in students from low socioeconomic communities. It mentions that the internet-supported professional learning intervention for physical education teachers improve the proportion of time that students spend in moderate to-vigorous physical activity in physical education classes.

• We examined panic buying and hoarding at the onset of the COVID-19 outbreak. • Perceived scarcity was the strongest predictor of panic buying. • Intolerance of uncertainty was the strongest predictor of hoarding. • Buying restrictions imposed by retailers may reduce panic buying. The COVID-19 pandemic led to panic buying in many countries across the globe, preventing vulnerable groups from accessing important necessities. Some reports inaccurately referred to the panic buying as hoarding. Although hoarding is a separate issue characterised by extreme saving behaviour, the two problems may be influenced by similar factors. Participants from Australia and the United States (final N = 359) completed online self-report measures of panic buying, hoarding, shopping patterns, perceived scarcity, COVID-19 illness anxiety, selfishness, and intolerance of uncertainty. Our findings showed that panic buying was related to hoarding symptoms (r 's =.23 -.36), and yet, both were uniquely associated with different psychological factors. Whilst panic buying was most strongly related to greater perceived scarcity (r 's =.38 -.60), hoarding was most related to a general intolerance of uncertainty (r 's =.24 -.57). Based on our findings, future strategies to prevent panic buying should focus on reducing perceived scarcity cues in the community, as this seems to be the primary driver of panic buying. Another preventative strategy to reduce excessive acquiring and saving may be to implement educational programs to increase people's ability to tolerate distress and uncertainty. [ABSTRACT FROM AUTHOR]

The article focuses on no benefits for home-based rehabilitation for people with inoperable lung cancer over usual care.

The article focuses on the application of participation-focused therapy in children with cerebral palsy for improvement in physical activity goal performance, satisfaction, and confidence.

The article discusses the approaches for gluteal tendinopathy which includes education plus exercise and corticosteroid injection.

Adherence and accuracy of self-monitoring of dietary intake influences success in weight management interventions. Information technologies such as computers and smartphones have the potential to improve adherence and accuracy by reducing the burden associated with monitoring dietary intake using traditional paper-based food records. We evaluated the acceptability and accuracy of three different 7-day food record methods (online accessed via computer, online accessed via smartphone, and paper-based). Young women (N=18; aged 23.4±2.9 years; body mass index 24.0±2.2) completed the three 7-day food records in random order with 7-day washout periods between each method. Total energy expenditure (TEE) was derived from resting energy expenditure (REE) measured by indirect calorimetry and physical activity level (PAL) derived from accelerometers (TEE=REE×PAL). Accuracy of the three methods was assessed by calculating absolute (energy intake [EI]–TEE) and percentage difference (EI/TEE×100) between self-reported EI and TEE. Acceptability was assessed via questionnaire. Mean±standard deviation TEE was 2,185±302 kcal/day and EI was 1,729±249 kcal/day, 1,675±287kcal/day, and 1,682±352 kcal/day for computer, smartphone, and paper records, respectively. There were no significant differences between absolute and percentage differences between EI and TEE for the three methods: computer, –510±389 kcal/day (78%); smartphone, –456±372 kcal/day (80%); and paper, –503±513 kcal/day (79%). Half of participants (n=9) preferred computer recording, 44.4% preferred smartphone, and 5.6% preferred paper-based records. Most participants (89%) least preferred the paper-based record. Because online food records completed on either computer or smartphone were as accurate as paper-based records but more acceptable to young women, they should be considered when self-monitoring of intake is recommended to young women. [ABSTRACT FROM AUTHOR]

Although Australia's population is concentrated in major urban centres along its coastal fringe, its less populous rural communities are important to society and the economy—supporting sectors like agriculture, which occupies over half the continent's land mass and accounts for 2.2% of value added gross domestic product (GDP) (Jackson et al., 2020). The vast distances between urban and rural centres present challenges to the provision of essential infrastructure like roads, transport, energy – and telecommunications. Within this last category, internet connectivity and skills are both increasingly necessary and historically less available to the regional and rural agricultural sector in comparison to other industries and geographic communities. The digital inclusion agenda in Australia aims to address such gaps by promoting and supporting people and communities to use technology to improve social and economic well-being. This article builds on research underpinning the Australian Digital Inclusion Index (ADII), which defines digital inclusion as the capacity of people to access , afford and use online technologies effectively. The article focuses on the nature and extent of digital inclusion for Australia's farmers (identified as farmers and farm managers) based on analysis of a customised set of primary data extracted from the ADII dataset. This analysis reveals generally low levels of digital inclusion in rural communities, particularly among farmers, with distinctive and complex characteristics across measures of Access, Affordability and Digital Ability. Our findings highlight a perplexing scenario in which farmers score poorly on the Index when compared to Australians who live in similar circumstances but are not employed in the farming sector. We attribute lower levels of access to limited internet technology options, lower data speeds, inadequate reliability and lower data allowances. Less affordability is associated with individual-level socioeconomic factors, along with lack of competition between service providers in sparse population areas, the comparative cost of building telecommunications infrastructure in the bush, and the need for redundancy in rural and remote solutions. Finally, lower digital ability scores reflect social, cultural and material practices on farms that have produced distinctive orientations to technology. We conclude the article by explaining the contributions of the paper to digital inclusion research and by making recommendations for policy development. • Farmers in rural Australia have low levels of digital inclusion across access, affordability and digital ability. • Low access and affordability may be attributed to insufficient internet infrastructure and limited technology and data. • Low ability may be attributed to demographic factors and social, economic and material practices. • Governments and industry should consider the development of digital skills programs tailored for the farming sector. [ABSTRACT FROM AUTHOR]

It is generally accepted that the amino acid reagent consisting of 1,2-indanedione and a catalytic amount of zinc chloride, referred to as IND-Zn, is the single best method for the detection of latent fingermarks on paper substrates and that ninhydrin is of limited value when used in sequence after this reagent. However, recent research has suggested that the sequence 1,8-diazafluoren-9-one (DFO) followed by ninhydrin may actually produce a greater number of fingermarks than IND-Zn on its own or IND-Zn followed by ninhydrin. This study focussed on the evaluation of two fingermark detection sequences for porous surfaces: (1) IND-Zn followed by ninhydrin, physical developer (PD) and the lipid stain nile red; and (2) DFO followed by ninhydrin, PD and nile red. The evaluation was undertaken using a range of latent fingermark donors and on a number of paper substrates that are commonly encountered in Australia. In addition, a pseudooperational trial was completed on 5-year-old university examination booklets. Parallel studies were undertaken at two locations: Sydney (temperate, coastal climate) and Canberra (relatively dry, continental climate). The results of the donor study indicated that there was a negligible difference in performance between the two sequences across all paper types and all time periods evaluated. When considering individual reagents, IND-Zn generally developed better quality fingermarks compared to DFO; however, ninhydrin had a greater enhancement effect on DFO developed marks than after IND-Zn. In the pseudooperational trials, the IND-Zn sequence outperformed the DFO sequence. Nile red did not develop any additional marks at the end of each sequence and, as a result, the use of this technique at the end of a full sequence is of questionable value. The overall outcome was that the sequence IND-Zn followed by ninhydrin and PD is recommended for the processing of common paper substrates under the conditions typically experienced at the two locations studied. [ABSTRACT FROM AUTHOR]

Abstract: Coalbed methane (CBM) or coal seam gas (CSG) as it is known in Australia is becoming an increasingly important source of energy around the world. Many countries such as United States, Canada, Australia and China are investing in the CSG industry. A rise in the cost of conventional natural gas and many other energy resources, along with a decline in these conventional resources and issues such as climate change have encouraged a global interest in alternative sources of energy like CSG. The estimated quantity of CSG worldwide is around 1.4×1014 m3, it is clear that coal seam gas is a significant source of energy. The first section of this paper will discuss the production size of CSG worldwide and the future of the industry. The usage of the coal bed seam for the sequestration of CO2 is also an added benefit. The reduction of CO2 released to the environment may help in the future mitigation of global warming. In addition, the re-injecting of the co-produced CO2 enhances the commercial recovery and production of CSG wells. In the second section, the impact of the CSG industry's by-products on the environment, the freshwater ecosystem and human health are analysed. The second section includes issues associated with the large volume of co-produced water with undesirable composition in the CSG industry. The management of this enormous amount of water requires cost effective technologies and methods. Many methods for dealing with water problems are discussed and analysed in this paper. [Copyright &y& Elsevier]

Abstract: Purpose: To describe the paper-based and electronic formats of resident admission forms used in several aged care facilities in Australia and to compare the extent to which resident admission information was documented in paper-based and the electronic health records. Methods: Retrospective auditing and comparison of the documentation quality of paper-based and electronic resident admission forms were conducted. A checklist of admission data was qualitatively derived from different formats of the admission forms collected. Three measures were used to assess the quality of documentation of the admission forms, including completeness rate, comprehensiveness rate and frequency of documented data element. The associations between the number of items and their completeness and comprehensiveness rates were estimated at a general level and at each information category level. Results: Various paper-based and electronic formats of admission forms were collected, reflecting varying practice among the participant facilities. The overall completeness and comprehensiveness rates of the admission forms were poor, but were higher in the electronic health records than in the paper-based records (60% versus 56% and 40% versus 29% respectively, p <0.01). There were differences in the overall completeness and comprehensiveness rates between the different formats of admission forms (p <0.01). At each information category level, varying degrees of difference in the completeness and comprehensiveness rates were found between different form formats and between the paper-based and the electronic records. A negative association between the completeness rate and the number of items in a form was found at each information category level (p <0.01), i.e., more data items designed in a form, the less likely that the items would be completely filled. However, the associations between the comprehensiveness rates and the number of items were highly positive at both overall and individual information category levels (p <0.01), suggesting more items designed in a form, more information would be captured. Conclusion: Better quality of documentation in resident admission forms was identified in the electronic documentation systems than in previous paper-based systems, but still needs to be further improved in practice. The quality of documentation of resident admission data should be further analysed in relation to its specific content. [Copyright &y& Elsevier]

A lifecycle assessment to estimate greenhouse gas emissions in Australia from the paper cycle is summarised. The greenhouse gas emissions from paper in Australia in 1999/2000 were estimated to be 12.1 million tonnes (Mt) of CO2 equivalent. Nearly half of this amount consisted of CH4 emissions from landfilled waste paper. Various waste management options were modelled to investigate the greenhouse impact of a tonne of paper over its whole lifecycle. Options that keep paper out of landfills significantly reduce greenhouse emissions, waste-to-energy recovery being most effective. Recycling is also beneficial, and is of particular interest from a management perspective because it can be controlled by the pulp and paper industry. These findings can be extended to other wood-based and organic wastes. [Copyright &y& Elsevier]

An effective cleaner production programme requires the efficient collection and interpretation of data relating to a facility’s activities, including information of pollutant emissions, wastes generated and raw materials consumed. Many of these data are required to be collected and reported under national Pollutant Release and Transfers Registers (PRTRs) which are an increasingly common environmental policy tool in the OECD countries.This article considers the relationship between cleaner production and PRTR reporting, and discusses whether cleaner production programmes can be enhanced by the use of PRTR data. A case-study of a fertiliser manufacturing facility reporting under the Australian National Pollutant Inventory (NPI) is used to analyse and illustrate the practical issues around linking cleaner production with PRTR reporting.PRTR reporting can assist in identifying cleaner production opportunities and in generating the data sets required to design, implement and monitor cleaner production programmes. There are, however, some limitations in PRTR data that need to be recognised. Specifically, these are issues around data quality and comparability (e.g. PRTRs rely heavily on default emissions factors rather than the monitoring data that are generally required for cleaner production programmes) and the different data sets required for PRTR reporting (which generally require reporting at the site level rather than at the individual process unit level that is required for cleaner production). [Copyright &y& Elsevier]

• Good documentation practice is the foundation for promoting medication safety in young population. • Study identified poor documentation practice through paper and electronic means of medical records. • Newly introduced electronic medical records did not improve the rates of metabolic monitoring nor the quality of documented monitoring. • Youth are at significant risk for antipsychotic induced metabolic syndrome the repercussion of which may impact years of productivity. • Potentially electronic health records could provide health workers with real-time information access, and develop accurate, relevant and structured information thereby adhering to clinical evidence. Since the development of digital records, claims have been made that they improve audits. Clinical audits play important role in evaluation of evidence-practice gaps. Antipsychotic medications are one of the commonly prescribed group of drugs in severe adverse mental conditions. Youth and young people are highly prone to develop drug induced metabolic syndrome. Present study evaluated the extent of data documentation on evidence for metabolic monitoring of antipsychotics and compared paper based to electronic records with good documentation standards. First phase of this study involved a retrospective clinical audit of paper-based documentation on the extent of documentation of weight (primary outcome); lipid and blood glucose (secondary outcomes) of youth prescribed atypical antipsychotics. This was undertaken in three public mental health clinics and a public/private developmental service in Australia based on paper-based documentation. The second phase included auditing electronic data capture from one community clinic. Evidence of documentation was compared with practice standards and published clinical audits (adherence rate benchmark: 40–60%). A total of 310 cases were assessed of which 51 and 37 cases met the eligibility criteria for paper-based and electronic based audit respectively as a component of clinical audit. Evidence of paper documentation of weight was 43% among participants and was comparable with other published clinical audits (p = 0.07) with poor monitoring rates for other blood tests. Findings revealed poor rate of documentation at 35.1% (13 cases), 5.4% (2 cases) and 8.1% (3 cases) for weight, lipid assessments and glucose monitoring, respectively based on electronic records. Present study demonstrate lack of good documentation practices on metabolic monitoring of youth prescribed antipsychotics. It appears transitioning from paper to electronic records did not impact the rate of increase in documentation of metabolic monitoring. This study recommends inclusion of e-monitoring icon with built in metabolic monitoring chart as a component of youth prescribed antipsychotic case records. Good documentation practice is a first step in determination of causality of antipsychotics induced metabolic syndrome. Appropriate strategies to a user-friendly electronic reminder system will be crucial to address on the mechanistic of documentation. [ABSTRACT FROM AUTHOR]

Temperature cycling stability studies can be appropriately designed and utilized to ensure that drug product quality, efficacy, and safety are not compromised when materials are subjected to short term temperature excursions from intended storage that may occur during e.g., shipping, transport, or patient use. Some countries, such as Australia and Brazil, impose specific regulations that specify the need to conduct stability studies that are supportive of "real world" excursions as part of licensing approval requirements. These temperature cycling stability studies extend beyond what is described in ICH Guidelines Q1A(R2) and Q5C, and companies may be challenged in designing studies that not only satisfy country specific regulations, but also satisfy all global regulatory health authority expectations. This article focuses on responses to a cross-industry survey conducted within the International Consortium for Innovation and Quality (iqconsortium.org) member companies, regarding practices related to temperature cycling stability studies, in order to determine how these requirements are being interpreted and met. The results indicate that while there is no one-size-fits-all approach to performing temperature cycling stability studies, there are common and best practices that can be followed to satisfy global health authority regulatory guidelines and requirements. The purpose of this paper is to describe the outcome of an industry survey and common/best practices on temperature cycling stability studies performed on drug product (DP) to satisfy the requirements established for marketing authorizations in Australia and Brazil or any other countries that may have similar requirements. The framework is proposed within the context of late phase and commercial development of common biological and/or large molecule modalities, such as monoclonal antibodies (mAbs, including bispecific antibodies), fusion proteins, complex proteins, oligonucleotides, and antibody-drug conjugates (ADCs), but many of the general principles involved may be applied to other therapeutics, such as Virus Like Particles (VLP), gene or cell therapies (GTx or CTx), or vaccines. For the purposes of this paper, temperature cycling stability studies refer to studies that are designed, in part, to support short term temperature excursions that drug product may be subjected to during shipping and storage activities and is outside of the labeled storage condition of the product. [ABSTRACT FROM AUTHOR]

Travel Demand Management (TDM) initiatives are widely applied by transport planners to establish and enable appropriate use of critical transport infrastructure. Less attention has been given to the specific case of TDM in an education precinct (university) context. Travel Plans have been promoted as a means for an organisation to encourage sustainable travel choices by their employees, visitors and customers. This paper offers an empirical contribution to the literature through a comparative qualitative evaluation of selected University Sustainable Travel Plans (USTPs) in Australia to identify the most important questions that a USTP should address explicitly. The evaluation comprised identification of a set of evaluation questions, completion of a template for each USTP considered and application of a simple scoring exercise. We also identify TDM measures that have been introduced as part of a USTP in response to the typical travel patterns exhibited in university settings. A contribution of this paper is to create a means of comparison of USTPs and to establish the components of a comprehensive travel plan. • Conducts a comparative analysis of University Sustainable Travel Plans. • Explores international experience of Travel Demand Management (TDM) in an education precinct context. • Key components of University Sustainable Travel Plans are identified. • The important role of regular surveys of staff and student travel behaviour is highlighted. [ABSTRACT FROM AUTHOR]

More than 200,000 ha of short rotation Eucalyptus globulus plantations have been established in south-western Australia to supply wood for the pulp and paper industries. Sustaining the productivity of these tree crops over successive rotations will depend in part on maintenance of soil fertility, especially soil nitrogen (N) supply. We investigated the impact of four alternative strategies for management of harvest residues on soil N dynamics in recently logged first rotation plantations. The experiments were conducted over 5 years following harvesting at two sites with contrasting soils—a coarse textured grey sand over laterite (Podzol) with low natural fertility and a relatively fertile red earth soil (Ferralsol). At the grey sand site, 31 t ha−1 of residues containing 219 kg N ha−1 were deposited following harvest while at the red earth site the equivalent figures were 51 t ha−1 of residues and 347 kg N ha−1. Experimental treatments applied included residues burned, removed, retained and retained with double the amount of residues. The impact of treatments on soil nitrogen supply was investigated by incubating intact soil cores in the field to determine rates of net N mineralization. Additionally, the effect of treatments on soil moisture and temperature, the resident pool of soil mineral N and the amount of N potentially available for mineralization was assessed. The mulching effect of retained residues resulted in higher soil moisture where residues had been retained and a trend for soil on these treatments to dry out more slowly with the onset of the dry summer season, especially in the first year following harvest. Diurnal variations in soil temperature were moderated and average soil temperatures were reduced during summer where residues were retained. Concentrations of mineral N in soil were high in the 2 years following harvest at both sites and declined as newly established seedlings developed. At the more fertile site, where mineral N occurred predominantly as nitrate, retention of residues resulted in lower pools of soil mineral N following harvest. The effect of residue treatments on soil mineral N pools was less marked at the grey sand site. Concentrations of potentially mineralizable soil N and the amounts of N mineralized annually were greater where residues were retained at both sites. The results indicate that retention of harvest residues will favour the conservation of N following logging. However, accumulation of soil mineral N following harvesting due to reduced plant uptake will result in leaching of N early in the rotation that is largely independent of residue management. Retaining harvest residues will contribute to enhanced N supply for the next tree crop through mineralization in the long term. However, on some sites, additions of nitrogenous fertilizers will still be required to maximise the rate of tree growth. [Copyright &y& Elsevier]

Significant advances have been made in artificial intelligence technology in recent years. Many health care applications have been investigated to assist clinicians and the technology is close to being integrated into routine clinical practice. The high prevalence of cardiac disease in Australia places overwhelming demands on the existing health care system, challenging its capacity to provide quality patient care. Artificial intelligence has emerged as a promising solution. This discussion paper provides an Australian perspective on the current state of artificial intelligence in cardiology, including the benefits and challenges of implementation. This paper highlights some current artificial intelligence applications in cardiology, while also detailing challenges such as data privacy, ethical considerations, and integration within existing health infrastructures. Overall, this paper aims to provide insights into the potential benefits of artificial intelligence in cardiology, while also acknowledging the barriers that need to be addressed to ensure safe and effective implementation into an Australian health system. [ABSTRACT FROM AUTHOR]

This paper explores the skills landscape of the emerging green hydrogen industry in Australia drawing on data collected from a study that gathered insights on training gaps from a range of hydrogen industry participants. A total of 41 industry participants completed a survey and 14 of those survey respondents participated in industry consultations. The findings revealed widespread perceptions of training and skilling as being very important to the industry, but under-provisioned across the sector. Data were analysed to consider the problem of skilling the green hydrogen industry and the barriers and enablers as perceived by industry stakeholders. In this paper we argue that urgent cross-sector attention needs to be paid to hydrogen industry training and skill development systems in Australia if the promise of green hydrogen as a clean energy source is to be realised. • Cross-sector collaboration is needed to support education and training on hydrogen energy. • Insufficient training is available to support skill development in hydrogen energy. • Training on electrolysers, fuel cells, hydrogen storage and refuelling stations is most needed. [ABSTRACT FROM AUTHOR]

A dedicated grid-tied offshore hybrid energy system for hydrogen production is a promising solution to unlock the full benefit of offshore wind and solar energy and realize decarbonization and sustainable energy security targets in electricity and other sectors. Current knowledge of these offshore hybrid systems is limited, particularly in the integration, component control, and allocation aspects. Therefore, a grid-integrated analytical model with a power dispatch allocation strategy between the grid and electrolyzer for the co-production of hydrogen from the offshore hybrid energy system is developed in this paper. While producing hydrogen, the proposed offshore hybrid energy system supplies a percentage of its capacity to the onshore grid facility, and the amount of the electricity is quantified based on the electricity market price and available total offshore generation. The detailed controls of each component are discussed. A case study considers a hypothetical hybrid offshore energy system of 10 MW situated in a potential offshore off the NSW of Australia based on realistic metrological data. A grid-scale proton-exchange membrane electrolyzer stack is used and a model predictive power controller is implemented on the distributed hydrogen generation scheme. The model is helpful for the assessment or optimization of both the economics and feasibility of the dedicated offshore hybrid energy farm for hydrogen production systems. • Modeling of a grid-integrated analytical model of an OHES for hydrogen co-production. • Development of a power dispatch allocation strategy for the proposed OHES. • Development of detailed controls of each component used in the proposed OHES. • Demonstrations of a case study considering 10 MW OHES situated in offshore off the NSW of Australia. [ABSTRACT FROM AUTHOR]

Cities are under intensifying pressure to respond to climate change and growing social inequities. Integrating nature-based solutions, as part of essential city infrastructure, contributes to resilient, liveable and equitable cities, as well as provision of biodiversity habitat. There is increasing focus on how concepts of justice can be embedded in these planning and governance processes. This paper proposes a framework to inform planning for just nature-based cities. It brings together concepts of just city, environmental and climate justice and more-than-human thinking, with research on urban nature-based solutions. It highlights the centrality of epistemic justice, and the importance of Traditional Ecological Knowledge in just nature-based city planning and governance. The just nature-based city framework is applied to the case study of the Yarra River (Melbourne, Australia). In 2017, the Yarra River Protection (Wilip-gin Birrarung murron) Act, the first legislation in Australia to be co-titled in the Traditional Owners' language, legally recognised the river as a single living and integrated natural entity. Applying the just nature-based city framework, we find that there are both opportunities and challenges in this new approach to planning. While the Act and associated programs represent substantial and innovative advances, their scope is limited by exclusion of key policy domains and a focus on waterway corridor rather than catchment. The paper concludes by reinforcing the importance of a broadened understanding of justice, that spans both human and non-human considerations, and foregrounds Traditional Owners' perspectives and aspirations in designing, planning and governing just nature-based cities. • 'Just nature-based cities' integrate theories of just cities, nature-based solutions and epistemic justice. • The 'just nature-based city' framework can be applied as both a planning and an analytical tool. • Yarra River-Birrarung is a case study of new approaches to just nature-based city governance. [ABSTRACT FROM AUTHOR]

Abstract: Desalination of seawater accounts for a worldwide water production of 24.5 million m3/day. A “hot spot” of intense desalination activity has always been the Arabian Gulf, but other regional centers of activity emerge and become more prominent, such as the Mediterranean Sea and the Red Sea, or the coastal waters of California, China and Australia. Despite the many benefits the technology has to offer, concerns rise over potential negative impacts on the environment. Key issues are the concentrate and chemical discharges to the marine environment, the emissions of air pollutants and the energy demand of the processes. To safeguard a sustainable use of desalination technology, the impacts of each major desalination project should be investigated and mitigated by means of a project- and location-specific environmental impact assessment (EIA) study, while the benefits and impacts of different water supply options should be balanced on the scale of regional management plans. In this context, our paper intends to present an overview on present seawater desalination capacities by region, a synopsis of the key environmental concerns of desalination, including ways of mitigating the impacts of desalination on the environment, and of avoiding some of the dangers of the environment to desalination. [Copyright &y& Elsevier]

Strange as it may seem, Treasury, brewers, winemakers, distillers and drinkers all share a common interest: The taxation of alcohol and its price elasticity of demand. Treasury needs this information to determine revenue, the industry for pricing purposes, and drinkers bear the burden of taxation. This paper presents new estimates of demand elasticities of beer, wine and spirits for Australia. The estimates are considerably lower than those of Srivastava et al. (2014), who used monthly, off-premise consumption. Frequency of purchase and location of drinking are most likely the source of the differences. The paper demonstrates the importance of demand elasticities with simulations of changes in the tax mix for alcoholic beverages with partial and general equilibrium approaches. [ABSTRACT FROM AUTHOR]

Green hydrogen, produced from renewable electricity, can be transported long distances in multiple mediums. In this paper, a Techno-economic model is proposed to show the economic viability of global green hydrogen transport along 15 major regional routes such as Australia to Asia and Europe for the first time. A Monte Carlo-based technique is presented to assess the levelised cost of green hydrogen for different regions for the next 30 years. Depending on the specific route, green hydrogen can be transported in different forms, including ammonia, Liquid Organic Hydrogen Carrier (LOHC), Hydrogen Slush, compressed or liquefied hydrogen, etc. form and using different modes including shipping, truck, train, and pipeline. A linear programming analysis has been conducted for different regions, showing that among the global projected 300Mt of green hydrogen demand in 2050, 85% will need to be transported between regions to achieve the most economically optimal distribution. • Techno-economic analysis of green H 2 export via 15 worldwide regional trade routes. • Export model includes H2 generation, conversion, transport, and carbon prices. • In 2030, North America will be the largest exporter, followed by Australia. • Higher carbon prices allow for rapid growth in the green hydrogen industry. • Shipping is the most likely and cheapest H 2 export mode for distant transport. [ABSTRACT FROM AUTHOR]

Supporters of hydrogen energy urge scaling up technology and reducing costs for competitiveness. This paper explores how hydrogen energy technologies (HET) are perceived by Australia's general population and considers the way members of the public imagine their role in the implementation of hydrogen energy now and into the future. The study combines a nationally representative survey (n = 403) and semi-structured interviews (n = 30). Results show age and gender relationships with self-reported hydrogen knowledge. Half of the participants obtained hydrogen information from televised media. Strong support was observed for renewable hydrogen, while coal (26%) and natural gas (41%) versions had less backing. Participants sought more safety-related information (41% expressed concern). Most felt uncertain about influencing hydrogen decisions and did not necessarily recognise they had agency beyond their front fence. Exploring the link between political identity and agency in energy decision-making is needed, with energy democracy a potentially productive direction. • Hydrogen's strongest appeal to Australians is its benefit for climate change mitigation. • Although widely accepted, there is limited knowledge about hydrogen in terms of how it is produced or used. • The more people know about hydrogen, the more willing they are to participate in the decision-making process. [ABSTRACT FROM AUTHOR]

"Rural Australia" has long been a special site of political contestation. Staking the terms of public depictions of "the rural", "the bush", or "country life" is a constitutive thread running through Australian settler colonial identity and a cornerstone of national electoral politics. This paper analyses major News Corporation media outlets' presentation of an evolving political campaign, comparing contesting representations of farming and rural Australia deployed by the Morrison Coalition government and advocacy group Farmers for Climate Action, in the period between the government's re-election in May 2019 and July 2021. The paper steps through the key tactical discursive moves made by these contesting parties. It argues that in their depictions of rural Australia there are two important features that these perspectives share. Both embrace a discourse of increased agricultural productivity inspired by high-tech innovation, and both are silent on the related social and economic transformations that undergird the "crisis" of the rural. Consequently, public political contestation over rural policy unfolds without engaging transforming structural arrangements that fundamentally organise work and life on the land. • Presents comparative depictions of rurality by the Australian prime minister and advocacy group Farmers for Climate Action. • Political contests over the representation of the rural during the time of accelerating climate change are shown to have strong temporal framings. • Both government and Farmers for Climate Action embrace a discourse of increased agricultural productivity inspired by high-tech innovation and both are silent on socio-economic transformations. • Farmers for Climate Action have made significant steps towards normalising the idea that farming and climate activism go hand in hand. [ABSTRACT FROM AUTHOR]

This paper (Part 2 in the paper series), building on earlier studies examining the Australian response, extends on findings related to travel activity, commuting, and attitudes towards COVID-19 measures (Part 1 in the paper series). In this paper we focus in detail on the impact of, and experiences with, working from home (WFH), perhaps the largest of the positive unintended consequence of the pandemic, with respect to transport, and a key lens through which the changing patterns in travel activity and attitudes discussed in Part 1 need to be understood. We conclude that through the widespread adoption of WFH as a result of nationwide public health orders, there is evidence emerging that WFH is now seen as an appealing instrument of change by employees and employers, there is growing support to continue to support WFH into the future. This represents a significant potential contribution to the future management of the transport network, especially in larger metropolitan areas. We also discuss policy implications of this result and what the international community may take from the Australian experience. [ABSTRACT FROM AUTHOR]

While many countries have experienced more than one wave of the pandemic throughout 2020, Australia has been able to contain the virus in a way that makes it a stand out (with New Zealand) in the way that it has been contained, with an exception in Victoria linked to failed quarantine procedures for travellers returning from overseas. Through descriptive analysis, this paper builds on earlier papers by the authors on the Australian response, with a focus on the changing dynamics of travel activity, concern with public transport, and attitudes surrounding activity given the perception of risk of COVID-19 and the level of public support for regulatory intervention and restrictions on movement. We find that Australia continues to suppress travel, particularly that for commuting, that comfort in completing day-to-day activities continues to rise (with the exception of Victoria where confidence feel significantly), and while support for intervention measures remains high, there has been an erosion in sentiment. As with previous work, we discuss what this might mean for future transport policy, and attempt to draw lessons from the Australian experience. [Display omitted] [ABSTRACT FROM AUTHOR]

Hydrogen is a potential future solution addressing global warming, climate change, and energy security challenges. It efficiently allows for storing excess renewable energy and generating heat and electricity without increasing greenhouse gas emissions. It can create a practical pathway to replace fossil fuel vehicles and move toward a net-zero transport sector. Various hydrogen strategies and industry roadmaps have been developed to identify key goals, set targets for progress, and develop strategic plans to remove barriers. As identified through these documents, the development of consistent national and international codes and standards and the creation of clear procedures and regulations are essential for the safe implementation and adaptation of hydrogen systems, leading to the successful process of hydrogen sector. This paper provides a comprehensive and critical review of the different aspects of hydrogen safety to advance hydrogen regulations, codes, and standards. While it summarises the key international hydrogen frameworks, the main focus of the paper is on Australian plans, progress, and working groups for hydrogen deployment that will help future green energy society. • The safety developments affect the cost of Australian hydrogen scaling targets. • Training and safety developments are essential to achieve public trust in Australia. • Better community engagement is needed to move from hydrogen planning to its development. • Data-based tools assist the development of hydrogen safety procedures in Australia. [ABSTRACT FROM AUTHOR]

In nations where colonialism persists such as Australia, scholars have identified the hegemony of a morally infused white farming imaginary. While this construction has traditionally been invested in heteropatriarchal ideologies our aim in this paper is to demonstrate how, in recent years, white middle-class farming women have been woven into this narrative through settler colonial logics. We take up this contention in the Australian context examining 100 posts to two major institutional Instagram accounts that feature farming women: @invisfarmer and @agrifuturesau. Using the lens of settler colonialism, and a visual and textual analysis, we identify how the "white middle-class woman farmer" is framed by discourses of white feminism and invisibility/visibility. We reveal the emergence of a narrow farming woman aesthetic which is bolstered by narratives which celebrate the "successful female farmer" and the "successful female farm leader". In concluding the paper, we discuss the implications of the gendering of the white farming imaginary, and make a call for gender and rural studies scholars to de-centre and disaggregate the "white middle-class settler farming woman" subject position, through attending to settler colonialism and Indigenous scholarship in understandings of Australian rurality. • Australian rural studies uphold the "white middle-class settler farming woman". • The gendering of the white farming imaginary occurs through settler colonialism. • The "white middle-class woman farmer" is framed by discourses of white feminism. • Narratives of the "successful female farmer" and "leader" are celebrated. [ABSTRACT FROM AUTHOR]

Recently, Social Media (SM)'s adoption as educational instruments in Higher Education (HE) has been gaining popularity among researchers and practitioners. Nonetheless it has been adopted to support various learning approaches such as Cooperative Learning (CL). Despite the growing research in this field, few studies have proposed a comprehensive SM integration framework as well as empirical studies to evaluate its effectiveness. This paper examines how SM is being used as a pedagogical tool in HE and identifies major factors that drives SM's inclusion in HE classrooms. In addition, the paper investigates the effectiveness of a previously proposed integration framework which was developed to promote CL using a popular SM platform, LinkedIn. A survey was administered to collect data from students in different subjects at a university in Australia. Structural Equation Modelling (SEM) was adopted for data analysis using IBM's SPSS26 and AMOS26. One of the notable results of this study is the significant positive relation found between the use of the adopted integration framework and CL, SM challenges' mitigation, students' intention to use SM and their learning process. The findings of this study have important implications for practice and pave the way for future empirical studies. [ABSTRACT FROM AUTHOR]

• This paper presents the first on-the-ground study of attitudes towards just transition ideas in Australian coal communities. • It highlights the range of specific anxieties and reservations that workers and individuals in these communities have about these ideas. • The study highlights the dire need for local autonomy and control over any transition planning in these regions. Over the past several years, numerous actors across Australian society have increasingly advocated 'just transition' policies to help coal communities move beyond their reliance on fossil fuel extraction. As part of this, individuals from the environmental movement, trade unions, various NGOs and the private sector have called for a range of initiatives designed to help maintain the social and economic integrity of these regions as coal inevitably declines. Yet while just transition ideas have grown in popularity in these numerous forums in Australian society, it remains unclear how they are being understood by the very workers and communities for whom they are being proposed. To shed light on this question, we conducted interviews with residents of coal communities throughout Eastern Australia. We found that respondents had several key anxieties about just transition ideas and their impacts on their lives. In this paper, we break our findings down into five main themes that help explain these anxieties. [ABSTRACT FROM AUTHOR]

Nature-based solutions (NBS) are implemented across multiple cities worldwide and feature as promising solutions in local and global agendas. As solutions that can deal with interlinked urban challenges, NBS are being taken up by cities in different geographies and are considered to be mainstreaming. The process, referred to as mainstreaming, and how this can be achieved needs to be better understood, which is identified as a research gap. In this paper, we examine the roles that actors can undertake that contribute to the mainstreaming of NBS in cities. The aim is to understand the roles that urban actors, especially those within local governments, assume in the process of NBS mainstreaming to mobilise and implement novel and innovative strategic solutions for cities. This topic is explored in a case study of the metropolitan Melbourne region in Australia, where urban forest strategies are gaining traction in local governments for addressing urban resilience concerns. We present how the roles different actors assume contribute to the (re)shaping, building, and/or transformation of institutions to attain climate and ecologically resilient cities. The main contribution of this paper is a pathways framework that illustrates how sustainability norms can move through the mainstreaming process, facilitated by the roles that actors undertake – to champion, advocate, and realise transformative discourses and actions within urban politics and urban practices. Our key findings are framed as success factors of mainstreaming agencies and pathways underpinning transformation, which are: commitment longevity, innovative capacity, collaborative mindset, and on-ground delivery. • Policy, practice, and research actors can facilitate NBS mainstreaming in cities. • Role archetypes describe the mainstreaming actions of specific actors. • The configuration of roles is analysed to explain mainstreaming pathways. • Define mainstreaming pathways framework for actors' roles in NBS mainstreaming. • Success factors are commitment, innovation, collaboration, and on-ground delivery. [ABSTRACT FROM AUTHOR]

To clarify and elaborate on the choices that were made in the development of the Patient Scale of the Patient and Observer Scar Assessment Scale 3.0 (POSAS 3.0), based upon the rich information obtained from patients during focus groups and pilot tests. The discussions described in this paper are a reflection of the focus group study and pilot tests that were conducted in order to develop the Patient Scale of the POSAS3.0. The focus groups took place in the Netherlands and Australia and included 45 participants. Pilot tests were performed with 15 participants in Australia, the Netherlands, and the United Kingdom. We discussed the selection, wording and merging of 17 included items. Additionally, the reason for exclusion of 23 characteristics are given. Based upon the unique and rich material of patient input obtained, two versions of the Patient Scale of the POSAS3.0 were developed: the Generic version, and the Linear scar version. The discussions and decisions taken during the development are informative for a good understanding of the POSAS 3.0 and are indispensable as a background for future translations and cross-cultural adaptations. • The Patient Scale was meant to be concise, readily assessable, quick, and user-friendly instrument assessing the key attributes of scar quality. • Two versions have been developed, the Generic version (total of 16 items), and the Linear scar version (total of 17 items). • Eight of the identified characteristics were merged into three included items. • Twenty-three characteristics were excluded during different phases of the development process for multiple reasons. [ABSTRACT FROM AUTHOR]

This paper examines the role of socioeconomic status (SES) in affecting access to care and the survival of acute myocardial infarction (AMI) patients in Australia's universal health care system. We jointly model the probabilities of patients being admitted to a catheterisation-capable hospital, receiving invasive coronary angiography (ICA), and surviving 30 days post discharge as a recursive system of probit equations. We further investigate the role of capacity and whether the access gap between SES groups widens when capacity becomes limited. Our study shows that SES plays a significant role in affecting the survival of AMI patients, both directly and indirectly through healthcare access. We find that socioeconomically disadvantaged patients are less likely to gain access to crucial services like catheterisation hospitals and ICA, which indirectly affects their survival probability in addition to the adverse direct impact of SES. While healthcare capacity showed no overall effect on access, its interplay with SES exacerbates the access disparity in situations of limited capacity. Our findings suggest that, to reduce inequality in health outcomes, public health strategy needs to focus not only on enhancing access but also addressing the direct consequences of SES. [ABSTRACT FROM AUTHOR]

• Innovative phenotype-genotype association analysis for categorical genomic data having non-ignorable missing values. • Statistical learning method of random forest is used for variable selection in the analysis. • Weighted logistic ridge regression with EM algorithm is used for missing data imputation in the analysis. • Linear statistical hypothesis testing is used for determining the missingness mechanism in the analysis. • An application to analyzing real data from Australia breast cancer genome-wide association study (GWAS). Genomic data arising from a genome-wide association study (GWAS) are often not only of large-scale, but also incomplete. A specific form of their incompleteness is missing values with non-ignorable missingness mechanism. The intrinsic complications of genomic data present significant challenges in developing an effective and efficient procedure of phenotype-genotype association analysis by a statistical variable selection approach. In this paper we develop a coherent procedure of categorical phenotype-genotype association analysis, in the presence of missing values with non-ignorable missingness mechanism in genomic data. It is developed by integrating the statistical learning methods of random forest for variable selection, joint weighted logistic ridge regression with EM algorithm for missing data imputation, and linear statistical hypothesis testing for determining the missingness mechanism. Two simulated genomic datasets are used to undertake the phenotype-genotype association analysis by the proposed procedure, with the performance validated. The proposed procedure is then applied to analyze a real data set from breast cancer GWAS. [ABSTRACT FROM AUTHOR]

Green steel, produced using renewable energy and hydrogen, presents a promising avenue to decarbonize steel manufacturing and expand the hydrogen industry. Australia, endowed with abundant renewable resources and iron ore deposits, is ideally placed to support this global effort. This paper's two-step analytical approach offers the first comprehensive assessment of Australia's potential to develop green steel as a value-added export commodity. The Economic Fairways modelling reveals a strong alignment between prospective hydrogen hubs and current and future iron ore operations, enabling shared infrastructure development and first-mover advantages. By employing a site-based system optimization that integrates both wind and solar power sources, the cost of producing green steel could decrease significantly to around AU$900 per tonne by 2030 and AU$750 per tonne by 2050. Moreover, replacing 1% of global steel production would require 35 GW of well-optimized wind and solar photovoltaics, 11 GW of hydrogen electrolysers, and 1000 square kilometres of land. Sensitivity analysis further indicates that iron ore prices would exert a long-term influence on green steel prices. Overall, this study highlights the opportunities and challenges facing the Australian iron ore industry in contributing to the decarbonization of the global steel sector, underscoring the crucial role of government support in driving the growth and development of the green steel industry. [Display omitted] • Australia could produce low-cost green steel for value-added export • Strong correlation between hydrogen hubs and iron ore operations • Existing infrastructure supports the roll-out of the industry • Optimized generation mix reduces storage, curtailment and production costs • Iron ore prices substantially influence green steel prices in the long term [ABSTRACT FROM AUTHOR]

Developing a thriving hydrogen industry will depend on public and community support. Past research, mainly focusing on the acceptance of hydrogen fuelling stations and cars, suggests that people generally support hydrogen energy technology (HET). Few studies have, however, considered how people think about other components of the hydrogen supply chain (i.e., technologies required to make, store, transport and use hydrogen). Moreover, there has been limited research investigating how people interpret and develop beliefs about HET after being presented with technical information. This paper attempts to address these research gaps by presenting the findings from four face-to-face focus group discussions conducted in Australia. The findings suggest that people have differing views about HET, which depends on the type of technology, and these views influence levels of support. The study also revealed concerns about a range of other factors that have yet to be considered in hydrogen acceptance research (e.g., perceived water use, efficiency and indirect benefits). The findings highlight the value of qualitative research for identifying salient beliefs that shape attitudes towards HET and provide recommendations for future research and how to effectively communicate with the public and communities about an emerging hydrogen industry. • Focus group discussions with Australians about whole hydrogen supply chain. • Generally positive, but tentative, attitudes toward hydrogen overall. • Stronger support for industrial applications over domestic/household applications. • Concerns raised about hydrogen's efficiency and its conflict with other technologies. • Support for more research and pilot projects to provide tangible evidence. [ABSTRACT FROM AUTHOR]

Hydrogen supplying to industrial users is currently the major hydrogen business worldwide and the demand for hydrogen is almost entirely supplied from fossil fuels. In the last years a widespread interest on hydrogen has grown as energy vector for the decarbonization of multiple sectors, including industry, transport and buildings. Nevertheless, the impact of natural gas and other fossil fuels substitution with hydrogen is highly affected by the mix of different technologies and energy sources applied for hydrogen generation. The paper aims to investigate current CO 2 emissions related with hydrogen generation in Australia and Italy by means of PEM and alkaline technologies; and to evaluate the potential impact considering cell characteristics variation and 3 scenarios based on energy mix. A sensitivity analysis is performed to identify the critical parameters. Based on experimental data, the energy consumption for hydrogen production using PEM technology is more sensitive to cell voltage compared to current density, which indicates the importance of cell manufacturing and electrolyte resistance. In addition, by performing sensitivity analysis regarding energy sources scenarios it is found that carbon dioxide emission in Australia is more sensitive to renewable energy sources rather than Italy. [Display omitted] • Importance of manufacturing and electrolyte resistance because of high PEM energy consumption sensitivity to cell voltage. • Predicted emission in 2030 is 5–10 kg CO 2 using PEM/alkaline technology in Italy. • 18% reduction of national electricity grid CO 2 emission in Australia is predicted. (In 2030 in comparison to 2019). [ABSTRACT FROM AUTHOR]

The purpose of this research is to investigate the extent to which Australia's northern cities have become increasingly important mediators of migration of nurses and general practitioners (GPs) to the regional north since the 1980s. Over that period, national and provincial policy has focused on 'regionalisation' of health workforce development, including creating education and training infrastructure outside of metropolitan areas. This paper hypothesises that the effectiveness of regionalisation in northern Australia should be reflected in an increased net flow of GPs and nurses from northern cities (which are the hubs of education and training) to the regional north. Data from the seven Australian Census between 1986 and 2016 are used to model changing patterns of migration. Overall, there was limited evidence of substantial change in migration patterns, although for GPs there was a reduction in migration from the key metropolitan source markets (Brisbane and Adelaide) matching an increase in supply from northern cities. Northern cities have consistently been the source of about one quarter of new nurse and GP migrants to the regional north, but the regional north has become a much less favoured destination for professionals leaving northern cities as cities' populations have grown much faster than regional populations. Net flows have remained small and for nurses have favoured the cities while for GPs favoured the regional north. The paper concludes that, while there is limited evidence of increased 'spillover' of labour from the cities to the regional north, there is also no evidence of the cities increasingly 'spongeing' regional labour. Cities and regional migration systems may be increasingly disconnected as labour demands diverge, but new connections are being created with the rest of non-metropolitan Australia. The research is the first to analyse health professional migration over such a long period, and contributes to the debates about the roles of cities in sparsely populated areas in the development of their rural and remote hinterlands. • There is no evidence of increasing 'sponge' or 'spillover' relationships between northern cities and the regional north. • Large investment in 'regionalisation' of workforce development has not led to an increase in intra-northern migration. • There is evidence of increasing net loss of health professionals from the regional north to other regional Australia. • Regionalisation may be an ineffective strategy for growing the health professional workforce in the regional north. [ABSTRACT FROM AUTHOR]

• South Australia is leading low carbon energy transitions in Australia. • Socio-technical transitions are complex, non-linear and follow multiple adaptive pathways. • Complex adaptive systems and risk society theory can be integrated to better understand transitions. • Bold leadership and innovative policy are required to navigate transitions in a reflexive modernity. • Governance can exploit crises to justify transition policy in response to future risk and uncertainty. Renewable energy transitions are occurring across the globe in response to climate change. Such socio-technical transitions are complex and non-linear. They require bold leadership and innovative policy, both in response to environmental risk and to navigate political, technical and socio-economic conditions. This paper integrates complex adaptive systems and risk society theory to inform a discussion on regional socio-technical transitions. South Australia is forging its own adaptive pathway, and in doing so, is leading energy transitions in Australia. Utilising the complex adaptive cycle to frame the state's renewable energy transition, the path can be seen to be evolving from a simple first modernity to a multi-dimensional second modernity. Socio-technical transitions are partly a by-product of responses to risk. While there is no single map for navigating societal transitions, this paper proposes that risk, in the context of risk society theory, is an important guiding dimension for understanding transformational change in socio-technical systems. [ABSTRACT FROM AUTHOR]

This is the fourth in a series of papers that provides an historical record in this journal of contributions made by the most influential figures in the field of stuttering. Ann Packman is an Australian researcher who will retire shortly. This paper reflects on her long and productive career, and her contributions to the field. With a background in literature, linguistics, philosophy, psychology, and the brain and language, she became well equipped to contribute to understanding stuttering causality. That work, and an accompanying collection of basic and applied clinical research, was constantly grounded with the thoughts and feelings of those who stutter in the community. • Ann Packman is an Australian researcher who will retire shortly. • This paper reflects on her career and her contributions to the field. • Her work was grounded with the thoughts and feelings of those who stutter. [ABSTRACT FROM AUTHOR]