Author: "P. Archambault" / Publisher: elsevier - Searchworks@Jio Institute Digital Library Search Results

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1. Redefining on-farm practices: The perceived effect of a responsible antimicrobial use regulation on dairy farmers

Author: Nikky Millar, Simon Dufour, Hélène Lardé, Jonathan Massé, Maud De Lagarde, Marie Archambault, John Morris Fairbrother, Jean-Philippe Roy, Catherine Belloc, David Francoz, and Cécile Aenishaenslin
Subjects: antimicrobial use, dairy, regulation, practices, Dairy processing. Dairy products, SF250.5-275, Dairying, SF221-250
Abstract: ABSTRACT: The global food animal industry faces a growing concern regarding antimicrobial resistance (AMR), primarily driven by the use of antimicrobials (AM) for the treatment, control, and prevention of diseases. Addressing this challenge requires promoting responsible antimicrobial use (AMU) practices. In 2019, the province of Québec, Canada, took a significant step by implementing a regulation that limits the use of AM of very high importance for human medicine (category I AM as defined by Health Canada) in the food animal industry. However, the implementation of such regulation can significantly influence behavioral shifts among producers, contributing to the wider effort against AMR. Therefore, the objective of this observational study was to describe the perceived changes in dairy producers' knowledge and on-farm practices following the implementation of this regulation, using a cohort design. Data collection involved administering questionnaires to 87 dairy producers from 3 regions of the province of Québec (Estrie, Montérégie, Centre-Du-Québec) before (2017–2018) and after (2020–2021) the implementation of the regulation. The questionnaires explored the descriptive characteristics of farms, the knowledge of producers about the categorization of AM, the on-farm treatment practices, and the perceived effects of the regulation. Statistical analysis included t-tests and McNemar tests to compare the paired data obtained using the 2 questionnaires. The results indicated an increase in the knowledge score (the number of AM correctly categorized by the producers by their importance for human medicine) after the implementation of the regulation, suggesting an improved understanding of the categorization of AM based on their importance for human medicine. Trends in AMU practices for treating clinical mastitis and reproductive diseases suggested that category I AM were less likely to be reported as the primary treatment after the regulation, whereas category II AM were more often reported as primary treatment. Adoption of the selective dry cow therapy method significantly increased, whereas the use of teat sealants remained unchanged. Moreover, producers had divergent perceptions regarding the effect of the regulation on the cure rates and disease frequencies. This disparity emphasizes the need for comprehensive data collection to discern the risks associated with such regulatory shifts. The study acknowledges several limitations, including the potential for recall bias, confirmation bias, and desirability bias. Despite these limitations, this study shows that implementing regulations to encourage responsible AMU drives positive transformations in producers' knowledge and on-farm practices. This underscores the pivotal effect of proactive interventions in combating the escalating threat of AMR within the global food animal industry.
Published: 2024
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2. Rates of Reoperation in Duane Retraction Syndrome

Author: Han Woong Lim, MD, PhD, Bryce Hwang, MD, Cyril Archambault, MD, and Scott R. Lambert, MD
Subjects: Duane retraction syndrome, Reoperation, Strabismus surgery, Y splitting, Insurance claims data, Ophthalmology, RE1-994
Abstract: Purpose: To investigate the types of strabismus surgeries performed and the reoperation rate in patients with Duane retraction syndrome (DRS). Design: Retrospective cohort analysis. Participants: An insurance claims data set was used to identify patients diagnosed with DRS between 2007 and 2021. Methods: We recorded the type of strabismus surgery performed and the timing and frequency of reoperations. The hazard ratios (HRs) for reoperation were estimated according to the surgical methods using Cox regression analysis. Results: Of the 9435 patients diagnosed with DRS, 1023 (10.8%) underwent ≥ 1 strabismus operation. The median age at surgery was 5.0 years, and patients were followed for an average of 3.8 ± 3.0 years after their initial strabismus surgery. Most of the surgeries only involved horizontal muscle(s) (n = 734 [71.7%]). However, some patients underwent surgeries on vertical muscle(s) (n = 132 [12.9%]), vertical muscle(s) with transposition (n = 102 [10.0%]), and horizontal muscle with transposition (n = 51 [5.0%]). The estimated 5-year rate of reoperation was 18.2% (95% confidence interval [CI], 15.0%–22.2%). Compared with surgery on horizontal muscle(s) only, vertical muscle surgery (HR, 2.01; 95% CI, 1.30–3.11; P = 0.002) and vertical muscle surgery coupled with transposition (HR, 1.79; 95% CI, 1.06–3.02; P = 0.03) had an increased risk of reoperation. Conclusions: Strabismus surgery on ≥ 1 horizontal muscles is the most common type of strabismus surgery performed on patients with DRS. Approximately 1 in 7 patients with DRS who had strabismus surgery underwent a reoperation. Patients who underwent vertical muscle surgery had a higher risk of undergoing a reoperation. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
Published: 2024
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3. Nonmedical problems among older adults visiting the emergency department for low acuity conditions: A prospective multicentre cohort study

Author: Katherine Tanguay, Alexandra Nadeau, Audrey-Anne Brousseau, Patrick M. Archambault, Pierre-Hugues Carmichael, Marcel Emond, Jean-Francois Deshaies, Marie-Josée Sirois, Fabrice I. Mowbray, Pierre-Gilles Blanchard, and Eric Mercier
Subjects: Science (General), Q1-390, Social sciences (General), H1-99
Abstract: Background: Data on the predictors of nonmedical problems (NMP) in older adults attending the emergency department (ED) for low acuity conditions is lacking and could help rapid identification of patients with NMP and integration of these needs into care planning. Objectives: To determine the prevalence and predictors of NMP among older adults attending EDs for low acuity conditions. Methods: Prospective cohort study in eight EDs (May–August 2021). We included cognitively intact ≥65 years old adults assigned a low triage acuity (3–5) using the CTAS. A questionnaire focusing on 11 NMP was administered. We used multiple logistic regression to identify predictors of NMP. Results: Among the 1,061 participants included, the mean age was 77.1 ± 7.6, majority were female, and 41.6 % lived alone. At least one NMP was reported by 704 persons. Prevalence of each NMP: outdoor (41.1 %) and indoor (30.2 %) mobility issues, difficult access to dental care (35.1 %), transportation (4.1 %) and medication (5.4 %), loneliness (29.5 %), food insecurity (10.3 %), financial difficulties (9.5 %), unsafe living situation (4.1 %), physical/psychological violence (3.4 %), and abuse/neglect (3.3 %). Predictors of NMP were: age (OR 1.04 for each additional year), living alone (OR 2.20), pre-existing mental health conditions (OR 3.12), heart failure (OR 1.42), recent surgery/admission (OR 1.75), memory decline (OR 2.76), no family physician (OR 1.74) and consulting for a fall/functional decline (OR 2.48). Conclusions: Nonmedical problems are frequent among older adults. We need to implement holistic ED processes that integrate these problems into care planning.
Published: 2024
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4. Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms

Author: Barbara Wanjiru Citarella, Christiana Kartsonaki, Elsa D. Ibáñez-Prada, Bronner P. Gonçalves, Joaquin Baruch, Martina Escher, Mark G. Pritchard, Jia Wei, Fred Philippy, Andrew Dagens, Matthew Hall, James Lee, Demetrios James Kutsogiannis, Evert-Jan Wils, Marília Andreia Fernandes, Bharath Kumar Tirupakuzhi Vijayaraghavan, Prasan Kumar Panda, Ignacio Martin-Loeches, Shinichiro Ohshimo, Arie Zainul Fatoni, Peter Horby, Jake Dunning, Jordi Rello, Laura Merson, Amanda Rojek, Michel Vaillant, Piero Olliaro, Luis Felipe Reyes, S.A. Moharam, Sabriya Abdalasalam, Alaa Abdalfattah Abdalhadi, Naana Reyam Abdalla, Walaa Abdalla, Almthani Hamza Abdalrheem, Ashraf Abdalsalam, Saedah Abdeewi, Esraa Hassan Abdelgaum, Mohamed Abdelhalim, Mohammed Abdelkabir, Israa Abdelrahman, Sheryl Ann Abdukahil, Lamees Adil Abdulbaqi, Salaheddin Abdulhamid, Widyan Abdulhamid, Nurul Najmee Abdulkadir, Eman Abdulwahed, Rawad Abdunabi, Ryuzo Abe, Laurent Abel, Ahmed Mohammed Abodina, Amal Abrous, Lara Absil, Kamal Abu Jabal, Nashat Abu Salah, Abdurraouf Abusalama, Tareg Abdallah Abuzaid, Subhash Acharya, Andrew Acker, Elisabeth Adam, Safia Adem, Manuella Ademnou, Francisca Adewhajah, Diana Adrião, Anthony Afum-Adjei Awuah, Melvin Agbogbatey, Saleh Al Ageel, Aya Mustafa Ahmed, Musaab Mohammed Ahmed, Shakeel Ahmed, Zainab Ahmed Alaraji, Abdulrahman Ahmed Elhefnawy Enan, Reham Abdelhamid Ahmed Khalil, Ali Mostafa Ahmed Mohamed Abdelaziz, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Aisha, Bugila Aisha, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Chika Akwani, Eman Al Qasim, Ahmed Alajeeli, Ahmed Alali, Razi Alalqam, Aliya Mohammed Alameen, Mohammed Al-Aquily, Zinah A. Alaraji, Khalid Albakry, Safa Albatni, Angela Alberti, Osama Aldabbourosama, Tala Al-dabbous, Amer Aldhalia, Abdulkarim Aldoukali, Senthilkumar Alegesan, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Asil Alflite, Huda Alfoudri, Qamrah Alhadad, Hoda Salem Alhaddad, Maali Khalid Mohamed Abdalla Alhasan, Ahmad Nabil Alhouri, Hasan Alhouri, Adam Ali, Imran Ali, Maha TagElser Mohammed Ali, Syed Ali Abbas, Yomna Ali Abdelghafar, Naseem Ali Sheikh, Kazali Enagnon Alidjnou, Mahmoud Aljadi, Sarah Aljamal, Mohammed Alkahlout, Akram Alkaseek, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Lana Almasri, Abdulrahman Almjersah, Raja Ahmed Alqandouz, Walaa Alrfaea, Moayad Alrifaee, Rawan Alsaadi, Yousef Al-Saba'a, Entisar Alshareea, Eslam Alshenawy, Aneela Altaf, João Melo Alves, João Alves, Rita Alves, Joana Alves Cabrita, Maria Amaral, Amro Essam Amer, Nur Amira, Amos Amoako Adusei, John Amuasi, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Sophia Ankrah, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Angel Asensio, Elizabeth A. Ashley, Muhammad Ashraf, Muhammad Sheharyar Ashraf, Abir Ben Ashur, Franklin Asiedu-Bekoe, Namra Asif, Mohammad Asim, Grace Assi, Jean Baptiste Assie, Amirul Asyraf, Fouda Atangana, Ahmed Atia, Minahel Atif, Asia Atif Abdelrhman Abdallahrs, Anika Atique, Moad Atlowly, AM Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Abdelmalek Awad Ali Mohammed, Eyvind W. Axelsen, Ared Ayad, Ahmed Ayman Hassan Helmi, Laurène Azemar, Mohammed Azizeldin, Cecile Azoulay, Hakeem Babatunde, Benjamin Bach, Delphine Bachelet, Claudine Badr, Roar Bævre-Jensen, Nadia Baig, John Kenneth Baillie, J Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Hibah Bileid Bakeer, Ashraf Bakri, Andriy Bal, Mohanaprasanth Balakrishnan, Irene Bandoh, Firouzé Bani-Sadr, Renata Barbalho, Nicholas Yuri Barbosa, Wendy S. Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Cleide Barrigoto, Marie Bartoli, Joaquín Baruch, Romain Basmaci, Muhammad Fadhli Hassin Basri, AbdAlkarim Batool, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Abigail Beane, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Sylvie Behilill, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Lamis Berdeweel, Delphine Bergeaud, Hazel Bergin, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Krishna Bhavsar, Isabella Bianchi, Claudia Bianco, Sandra Bichoka, Farah Nadiah Bidin, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, Muhannud Binnawara, Zeno Bisoffi, Patrick Biston, Laurent Bitker, Mustapha Bittaye, Jonathan Bitton, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Filomena Boccia, Laetitia Bodenes, Debby Bogaert, Anne-Hélène Boivin, Ariel Bolanga, Isabela Bolaños, Pierre-Adrien Bolze, François Bompart, Aurelius Bonifasius, Joe Bonney, Diogo Borges, Raphaël Borie, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Latsaniphone Bountthasavong, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Marielle Boyer-Besseyre, Maria Boylan, Fernando Augusto Bozza, Axelle Braconnier, Cynthia Braga, Timo Brandenburger, Filipa Brás Monteiro, Luca Brazzi, Dorothy Breen, Patrick Breen, David Brewster, Kathy Brickell, Tessa Broadley, Helen Brotherton, Alex Browne, Nicolas Brozzi, Sonja Hjellegjerde Brunvoll, Marjolein Brusse-Keizer, Petra Bryda, Nina Buchtele, Polina Bugaeva, Marielle Buisson, Danilo Buonsenso, Erlina Burhan, Donald Buri, Aidan Burrell, Ingrid G. Bustos, Denis Butnaru, André Cabie, Susana Cabral, Joana Cabrita, Eder Caceres, Cyril Cadoz, Rui Caetano Garcês, Kate Calligy, Jose Andres Calvache, João Camões, Valentine Campana, Paul Campbell, Josie Campisi, Cecilia Canepa, Mireia Cantero, Janice Caoili, Pauline Caraux-Paz, Sheila Cárcel, Filipa Cardoso, Filipe Cardoso, Nelson Cardoso, Sofia Cardoso, Simone Carelli, Nicolas Carlier, Thierry Carmoi, Gayle Carney, Inês Carqueja, Marie-Christine Carret, François Martin Carrier, Ida Carroll, Gail Carson, Maire-Laure Casanova, Mariana Cascão, Siobhan Casey, José Casimiro, Bailey Cassandra, Silvia Castañeda, Nidyanara Castanheira, Guylaine Castor-Alexandre, Ivo Castro, Ana Catarino, François-Xavier Catherine, Paolo Cattaneo, Roberta Cavalin, Giulio Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Masaneh Ceesay, Shelby Cerkovnik, Minerva Cervantes-Gonzalez, Muge Cevik, Anissa Chair, Catherine Chakveatze, Adrienne Chan, Meera Chand, Jean-Marc Chapplain, Charlotte Charpentier, Julie Chas, Muhammad Mobin Chaudry, Jonathan Samuel Chávez Iñiguez, Anjellica Chen, Yih-Sharng Chen, Léo Chenard, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Suresh Kumar Chidambaram, Leong Chin Tho, Catherine Chirouze, Davide Chiumello, Sung-Min Cho, Bernard Cholley, Danoy Chommanam, Marie-Charlotte Chopin, Yock Ping Chow, Ting Soo Chow, Nathaniel Christy, Hiu Jian Chua, Jonathan Chua, Jose Pedro Cidade, José Miguel Cisneros Herreros, Anna Ciullo, Jennifer Clarke, Rolando Claure-Del Granado, Sara Clohisey, Cassidy Codan, Caitriona Cody, Jennifer Coles, Megan Coles, Gwenhaël Colin, Michael Collins, Pamela Combs, Jennifer Connolly, Marie Connor, Anne Conrad, Elaine Conway, Graham S. Cooke, Hugues Cordel, Amanda Corley, Sabine Cornelis, Alexander Daniel Cornet, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Juthaporn Cowan, Rachel Cregan, Gloria Crowl, Jonathan Crump, Claudina Cruz, Marc Csete, Ailbhe Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Colleen Curran, Paula Custodio, Ana da Silva Filipe, Charlene Da Silveira, Al-Awwab Dabaliz, John Arne Dahl, Darren Dahly, Umberto D'Alessandro, Peter Daley, Zaina Dalloul, Heidi Dalton, Jo Dalton, Seamus Daly, Juliana Damas, Joycelyn Dame, Cammandji Damien, Nick Daneman, Jorge Dantas, Frédérick D'Aragon, Gillian de Loughry, Diego de Mendoza, Etienne De Montmollin, Rafael Freitas de Oliveira França, Ana Isabel de Pinho Oliveira, Rosanna De Rosa, Cristina De Rose, Thushan de Silva, Peter de Vries, Jillian Deacon, David Dean, Alexa Debard, Bianca DeBenedictis, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Romain Decours, Eve Defous, Isabelle Delacroix, Alexandre Delamou, Eric Delaveuve, Karen Delavigne, Nathalie M. Delfos, Ionna Deligiannis, Andrea Dell'Amore, Christelle Delmas, Pierre Delobel, Corine Delsing, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhangar, Alpha Diallo, Souleymane Taran Diallo, Sylvain Diamantis, André Dias, Fernanda Dias Da Silva, Rodrigo Diaz, Juan Jose Diaz, Priscila Diaz, Bakary K. Dibba, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Fara Diop, Alphonsine Diouf, Yael Dishon, Cedric Djadda, Félix Djossou, Annemarie B. Docherty, Helen Doherty, Arjen M. Dondorp, Christl A. Donnelly, Yoann Donohue, Sean Donohue, Peter Doran, Céline Dorival, Eric D'Ortenzio, Yash Doshi, Phouvieng Douangdala, James Joshua Douglas, Renee Douma, Nathalie Dournon, Joanne Downey, Mark Downing, Thomas Drake, Aoife Driscoll, Ibrahim Kwaku Duah, Claudio Duarte Fonseca, Vincent Dubee, François Dubos, Audrey Dubot-Pérès, Alexandre Ducancelle, Toni Duculan, Susanne Dudman, Abhijit Duggal, Paul Dunand, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham, III, Bertrand Dussol, Juliette Duthoit, Xavier Duval, Anne Margarita Dyrhol-Riise, Sim Choon Ean, Ada Ebo, Marco Echeverria-Villalobos, Michael Edelstein, Siobhan Egan, Linn Margrete Eggesbø, Khadeja Ehzaz, Carla Eira, Mohammed El Sanharawi, Marwan El Sayed, Mohammed Elabid, Mohamed Bashir Elagili, Subbarao Elapavaluru, Mohammad Elbahnasawy, Sohail Elboshra, Brigitte Elharrar, Jacobien Ellerbroek, Merete Ellingjord-Dale, Hamida ELMagrahi, Mohammad Muatasm Elmubark, Loubna Elotmani, Lauren Eloundou, Philippine Eloy, Basma Elshaikhy, Tarek Elshazly, Wafa Elsokni, Aml Ahmed Eltayeb, Iqbal Elyazar, Zarief Kamel Emad, Hussein Embarek, Isabelle Enderle, Tomoyuki Endo, Gervais Eneli, Chan Chee Eng, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Haneen Esaadi, Mariano Esperatti, Hélène Esperou, Catarina Espírito Santo, Marina Esposito-Farese, Rachel Essaka, Lorinda Essuman, João Estevão, Manuel Etienne, Anna Greti Everding, Mirjam Evers, Isabelle Fabre, Marc Fabre, Ismaila Fadera, Asgad Osman Abdalla Fadlalla, Amna Faheem, Arabella Fahy, Cameron J. Fairfield, Zul Fakar, Komal Fareed, Pedro Faria, Ahmed Farooq, Hanan Fateena, Mohamed Fathi, Salem Fatima, Karine Faure, Raphaël Favory, Mohamed Fayed, Niamh Feely, Jorge Fernandes, Susana Fernandes, François-Xavier Ferrand, Eglantine Ferrand Devouge, Joana Ferrão, Mário Ferraz, Benigno Ferreira, Isabel Ferreira, Bernardo Ferreira, Sílvia Ferreira, Nicolas Ferriere, Céline Ficko, Claudia Figueiredo-Mello, William Finlayson, Thomas Flament, Tom Fletcher, Aline-Marie Florence, Letizia Lucia Florio, Brigid Flynn, Deirdre Flynn, Jean Foley, Victor Fomin, Tatiana Fonseca, Patricia Fontela, Karen Forrest, Simon Forsyth, Denise Foster, Giuseppe Foti, Berline Fotso, Erwan Fourn, Robert A. Fowler, Marianne Fraher, Diego Franch-Llasat, Christophe Fraser, John F. Fraser, Marcela Vieira Freire, Ana Freitas Ribeiro, Craig French, Caren Friedrich, Ricardo Fritz, Stéphanie Fry, Nora Fuentes, Masahiro Fukuda, G. Argin, Valérie Gaborieau, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Abdou Gai, Sérgio Gaião, Linda Gail Skeie, Adham Mohamed Galal Mohamed Ramadan, Phil Gallagher, Carrol Gamble, Yasmin Gani, Arthur Garan, Rebekha Garcia, Julia Garcia-Diaz, Esteban Garcia-Gallo, Navya Garimella, Denis Garot, Valérie Garrait, Basanta Gauli, Anatoliy Gavrylov, Alexandre Gaymard, Johannes Gebauer, Eva Geraud, Louis Gerbaud Morlaes, Nuno Germano, Malak Ghemmeid, Praveen Kumar Ghisulal, Jade Ghosn, Marco Giani, Tristan Gigante, Elaine Gilroy, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Gezy Giwangkancana, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jean-Christophe Goffard, Jin Yi Goh, Brigitta Golács, Jonathan Golob, Kyle Gomez, Joan Gómez-Junyent, Marie Gominet, Alicia Gonzalez, Patricia Gordon, Isabelle Gorenne, Laure Goubert, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Jeronimo Graf, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Lorenzo Grazioli, Christopher A. Green, Courtney Greene, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Ioana Grigoras, Albert Groenendijk, Fassou Mathias Grovogui, Heidi Gruner, Yusing Gu, Jérémie Guedj, Martin Guego, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Maisa Guimarães de Castro, Thomas Guimard, Marieke Haalboom, Daniel Haber, Ali Hachemi, Abdurrahman Haddud, Nadir Hadri, Wael Hafez, Fakhir Raza Haidri, Fatima Mhd Rida Hajij, Sheeba Hakak, Adam Hall, Sophie Halpin, Shaher Hamdan, Abdelhafeez Hamdi, Jawad Hameed, Ansley Hamer, Raph L. Hamers, Rebecca Hamidfar, Bato Hammarström, Naomi Hammond, Terese Hammond, Lim Yuen Han, Matly Hanan, Rashan Haniffa, Kok Wei Hao, Hayley Hardwick, Ewen M. Harrison, Janet Harrison, Samuel Bernard Ekow Harrison, Alan Hartman, Sulieman Hasan, Mohammad Ali Nabil Hasan, Mohd Shahnaz Hasan, Junaid Hashmi, Madiha Hashmi, Amoni Hassan, Ebtisam Hassanin, Muhammad Hayat, Ailbhe Hayes, Leanne Hays, Jan Heerman, Lars Heggelund, Ahmed Helmi, Ross Hendry, Martina Hennessy, Aquiles Rodrigo Henriquez-Trujillo, Maxime Hentzien, Diana Hernandez, Andrew Hershey, Liv Hesstvedt, Astarini Hidayah, Eibhlin Higgins, Rupert Higgins, Samuel Hinton, Hiroaki Hiraiwa, Haider Hirkani, Hikombo Hitoto, Antonia Ho, Yi Bin Ho, Alexandre Hoctin, Isabelle Hoffmann, Wei Han Hoh, Oscar Hoiting, Rebecca Holt, Jan Cato Holter, Juan Pablo Horcajada, Ikram Houas, Mabrouka Houderi, Catherine L. Hough, Stuart Houltham, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Abby Hurd, Iqbal Hussain, Aliae Mohamed Hussein, Mahmood Hussein, Fatima Ibrahim, Bashir Ibran, Samreen Ijaz, M. Arfan Ikram, Carlos Cañada Illana, Patrick Imbert, Muhammad Imran Ansari, Rana Imran Sikander, Hugo Inácio, Carmen Infante Dominguez, Yun Sii Ing, Mariachiara Ippolito, Vera Irawany, Sarah Isgett, Tiago Isidoro, Nadiah Ismail, Margaux Isnard, Mette Stausland Istre, Junji Itai, Daniel Ivulich, Danielle Jaafar, Salma Jaafoura, Hamza Jaber, Julien Jabot, Clare Jackson, Abubacarr Jagne, Stéphane Jaureguiberry, Denise Jaworsky, Florence Jego, Anilawati Mat Jelani, Synne Jenum, Ruth Jimbo-Sotomayor, Ong Yiaw Joe, Ruth Noemí Jorge García, Silje Bakken Jørgensen, Cédric Joseph, Mark Joseph, Swosti Joshi, Mercé Jourdain, Philippe Jouvet, Anna Jung, Hanna Jung, Dafsah Juzar, Ouifiya Kafif, Florentia Kaguelidou, Neerusha Kaisbain, Thavamany Kaleesvran, Sabina Kali, Karl Trygve Kalleberg, Smaragdi Kalomoiri, Muhammad Aisar Ayadi Kamaluddin, Armand Saloun Kamano, Zul Amali Che Kamaruddin, Nadiah Kamarudin, Kavita Kamineni, Darshana Hewa Kandamby, Kong Yeow Kang, Darakhshan Kanwal, Dyah Kanyawati, Mohamed Karghul, Pratap Karpayah, Todd Karsies, Daisuke Kasugai, Kevin Katz, Christy Kay, Lamees Kayyali, Seán Keating, Pulak Kedia, Andrea Kelly, Aoife Kelly, Claire Kelly, Niamh Kelly, Sadie Kelly, Yvelynne Kelly, Maeve Kelsey, Kalynn Kennon, Sommay Keomany, Maeve Kernan, Younes Kerroumi, Sharma Keshav, Shams Khail, Sarah Khaled, Imrana Khalid, Antoine Khalil, Irfan Khan, Quratul Ain Khan, Sushil Khanal, Abid Khatak, Krish Kherajani, Michelle E. Kho, Denisa Khoo, Ryan Khoo, Saye Khoo, Muhammad Nasir Khoso, Amin Khuwaja, Khor How Kiat, Yuri Kida, Peter Kiiza, Beathe Kiland Granerud, Anders Benjamin Kildal, Jae Burm Kim, Antoine Kimmoun, Detlef Kindgen-Milles, Nobuya Kitamura, Eyrun Floerecke Kjetland Kjetland, Paul Klenerman, Rob Klont, Gry Kloumann Bekken, Stephen R. Knight, Robin Kobbe, Paa Kobina Forson, Chamira Kodippily, Malte Kohns Vasconcelos, Sabin Koirala, Mamoru Komatsu, Franklina Korkor Abebrese, Volkan Korten, Stephanie Kouba, Mohamed Lamine Kourouma, Karifa Kourouma, Arsène Kpangon, Karolina Krawczyk, Ali Kredan, Vinothini Krishnan, Sudhir Krishnan, Oksana Kruglova, Anneli Krund, Pei Xuan Kuan, Ashok Kumar, Deepali Kumar, Ganesh Kumar, Mukesh Kumar, Dinesh Kuriakose, Ethan Kurtzman, Demetrios Kutsogiannis, Galyna Kutsyna, Ama Kwakyewaa Bedu-Addo, Sylvie Kwedi, Konstantinos Kyriakoulis, Marie Lachatre, Marie Lacoste, John G. Laffey, Nadhem Lafhej, Marie Lagrange, Fabrice Laine, Olivier Lairez, Sanjay Lakhey, Marc Lambert, François Lamontagne, Marie Langelot-Richard, Vincent Langlois, Eka Yudha Lantang, Marina Lanza, Cédric Laouénan, Samira Laribi, Delphine Lariviere, Stéphane Lasry, Sakshi Lath, Naveed Latif, Youssef Latifeh, Odile Launay, Didier Laureillard, Yoan Lavie-Badie, Andy Law, Cassie Lawrence, Teresa Lawrence, Minh Le, Clément Le Bihan, Cyril Le Bris, Georges Le Falher, Lucie Le Fevre, Quentin Le Hingrat, Marion Le Maréchal, Soizic Le Mestre, Gwenaël Le Moal, Vincent Le Moing, Hervé Le Nagard, Ema Leal, Marta Leal Santos, Biing Horng Lee, Heng Gee Lee, Su Hwan Lee, Jennifer Lee, Todd C. 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Moore, Lina Morales Cely, Marwa Morgom, Lucia Moro, Catherine Motherway, Ana Motos, Hugo Mouquet, Clara Mouton Perrot, Julien Moyet, Suleiman Haitham Mualla, Mohamed Muftah, Aisha Kalsoom Mufti, Ng Yong Muh, Mo'nes Muhaisen, Dzawani Muhamad, Jimmy Mullaert, Fredrik Müller, Karl Erik Müller, Daniel Munblit, Syed Muneeb Ali, Nadeem Munir, Laveena Munshi, Aisling Murphy, Patrick Murray, Marlène Murris, Srinivas Murthy, Himed Musaab, Alamin Mustafa, Mus'ab Mustafa, Dana Mustafa, Himasha Muvindi, Dimitra Melia Myrodia, Farah Nadia Mohd-Hanafiah, Behzad Nadjm, Dave Nagpal, Alex Nagrebetsky, Blanka Nagybányai-Nagy, Herwin Nanda Boudoin, Mangala Narasimhan, Nageswaran Narayanan, Prashant Nasa, Rashid Nasim Khan, Ahmad Nasrallah, Adel Gerges Nassif Metri, Alasdair Nazerali-Maitland, Nadège Neant, Holger Neb, Nikita Nekliudov, Matthew Nelder, Erni Nelwan, Raul Neto, Emily Neumann, Wing Yiu Ng, Pauline Yeung Ng, Anthony Nghi, Duc Nguyen, Orna Ni Choileain, Niamh Ni Leathlobhair, Nerissa Niba, Alistair D. Nichol, Prompak Nitayavardhana, Stephanie Nonas, Nurul Amani Mohd Noordin, Nurul Faten Izzati Norharizam, Anita North, Alessandra Notari, Mahdad Noursadeghi, Adam Nowinski, Saad Nseir, Leonard Numfor, Nurnaningsih Nurnaningsih, Dwi Utomo Nusantara, Elsa Nyamankolly, Anders Benteson Nygaard, Fionnuala O. Brien, Annmarie O. Callaghan, Annmarie O'Callaghan, Giovanna Occhipinti, Derbrenn OConnor, Max O'Donnell, Lawrence Ofori-Boadu, Tawnya Ogston, Takayuki Ogura, Tak-Hyuk Oh, Sophie O'Halloran, Katie O'Hearn, Sally-Ann Ohene, João Oliveira, Larissa Oliveira, Piero L. Olliaro, Cinderella Omar Rageh Elnaggar, Alsarrah Ali Mohammed Omer, Pierre Ondobo, David S.Y. Ong, Jee Yan Ong, Wilna Oosthuyzen, Anne Opavsky, Peter Openshaw, Saijad Orakzai, Claudia Milena Orozco-Chamorro, Jamel Ortoleva, Mohamed Osama Elsayed Soliman, Javier Osatnik, Linda O'Shea, Miriam O'Sullivan, Eman Othman, Siti Zubaidah Othman, Nadia Ouamara, Rachida Ouissa, Micheal Owusu, Ama Akyampomaa Owusu-Asare, Eric Oziol, Maïder Pagadoy, Justine Pages, Amanda Palacios, Massimo Palmarini, Giovanna Panarello, Hem Paneru, Lai Hui Pang, Mauro Panigada, Nathalie Pansu, Aurélie Papadopoulos, Rachael Parke, Melissa Parker, Jérémie Pasquier, Bruno Pastene, Fabian Patauner, Drashti Patel, Mohan Dass Pathmanathan, Luís Patrão, Patricia Patricio, Lisa Patterson, Rajyabardhan Pattnaik, Christelle Paul, Mical Paul, Jorge Paulos, William A. Paxton, Jean-François Payen, Sandra L. Peake, Kalaiarasu Peariasamy, Giles J. Peek, Florent Peelman, Nathan Peiffer-Smadja, Vincent Peigne, Mare Pejkovska, Paolo Pelosi, Ithan D. Peltan, Rui Pereira, Daniel Perez, Thomas Perpoint, Antonio Pesenti, Vincent Pestre, Lenka Petrou, Michele Petrovic, Ventzislava Petrov-Sanchez, Frank Olav Pettersen, Gilles Peytavin, Richard Odame Philips, Ooyanong Phonemixay, Soulichanya Phoutthavong, Michael Piagnerelli, Walter Picard, Olivier Picone, Maria de Piero, Djura Piersma, Carlos Pimentel, Raquel Pinto, Catarina Pires, Lionel Piroth, Ayodhia Pitaloka, Chiara Piubelli, Riinu Pius, Simone Piva, Laurent Plantier, Hon Shen Png, Julien Poissy, Ryadh Pokeerbux, Sergio Poli, Georgios Pollakis, Diane Ponscarme, Diego Bastos Porto, Andra-Maris Post, Douwe F. Postma, Pedro Povoa, Diana Póvoas, Jeff Powis, Sofia Prapa, Viladeth Praphasiri, Sébastien Preau, Christian Prebensen, Jean-Charles Preiser, Anton Prinssen, Gamage Dona Dilanthi Priyadarshani, Lucia Proença, Sravya Pudota, Bambang Pujo Semedi, Mathew Pulicken, Peter Puplampu, Gregory Purcell, Luisa Quesada, Vilmaris Quinones-Cardona, Else Quist-Paulsen, Mohammed Quraishi, Fadi Qutishat, Maia Rabaa, Christian Rabaud, Ebenezer Rabindrarajan, Aldo Rafael, Marie Rafiq, Abdelrahman Ragab, Mutia Rahardjani, Arslan Rahat Ullah, Ahmad Kashfi Haji Ab Rahman, Rozanah Abd Rahman, Fernando Rainieri, Giri Shan Rajahram, Pratheema Ramachandran, Nagarajan Ramakrishnan, José Ramalho, Ahmad Afiq Ramli, Blandine Rammaert, Grazielle Viana Ramos, Asim Rana, Rajavardhan Rangappa, Ritika Ranjan, Christophe Rapp, Aasiyah Rashan, Thalha Rashan, Ghulam Rasheed, Menaldi Rasmin, Indrek Rätsep, Cornelius Rau, Tharmini Ravi, Ali Raza, Andre Real, Stanislas Rebaudet, Sarah Redl, Brenda Reeve, Attaur Rehman, Muhammad Osama Rehman Khalid, Dag Henrik Reikvam, Renato Reis, Jonathan Remppis, Martine Remy, Hongru Ren, Hanna Renk, Anne-Sophie Resseguier, Matthieu Revest, Oleksa Rewa, Maria Ines Ribeiro, Antonia Ricchiuto, David Richardson, Denise Richardson, Laurent Richier, Siti Nurul Atikah Ahmad Ridzuan, Ana L. 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Scott, James Scott-Brown, Nicholas Sedillot, Tamara Seitz, Jaganathan Selvanayagam, Mageswari Selvarajoo, Malcolm G. Semple, Rasidah Bt Senian, Eric Senneville, Claudia Sepulveda, Filipa Sequeira, Tânia Sequeira, Ary Serpa Neto, Ellen Shadowitz, Syamin Asyraf Shahidan, Hamza Shahla, Laila Shalabi, Haitam Shames, Anuraj Shankar, Shaikh Sharjeel, Pratima Sharma, Catherine A. Shaw, Victoria Shaw, John Robert Sheenan, Dr. Rajesh Mohan Shetty, Rohan Shetty, Mohiuddin Shiekh, Nobuaki Shime, Keiki Shimizu, Sally Shrapnel, Shubha Kalyan Shrestha, Pramesh Sundar Shrestha, Hoi Ping Shum, Nassima Si Mohammed, Ng Yong Siang, Moses Siaw-Frimpong, Jeanne Sibiude, Bountoy Sibounheuang, Nidhal Siddig, Atif Siddiqui, Maqsood Ahmed Siddiqui, Louise Sigfrid, Fatoumata Sillah, Piret Sillaots, Catarina Silva, Maria Joao Silva, Rogério Silva, Benedict Sim Lim Heng, Wai Ching Sin, Dario Sinatti, Mahendra Singh, Punam Singh, Pompini Agustina Sitompul, Karisha Sivam, Vegard Skogen, Sue Smith, Benjamin Smood, Coilin Smyth, Morgane Snacken, Dominic So, Tze Vee Soh, Lene Bergendal Solberg, Joshua Solomon, Tom Solomon, Emily Somers, Agnès Sommet, Myung Jin Song, Rima Song, Tae Song, Jack Song Chia, Arne Søraas, Albert Sotto, Edouard Soum, Ana Chora Sousa, Marta Sousa, Maria Sousa Uva, Vicente Souza-Dantas, Mamadou Saliou Sow, Alexandra Sperry, Elisabetta Spinuzza, B. P. Sanka Ruwan Sri Darshana, Shiranee Sriskandan, Sarah Stabler, Thomas Staudinger, Stephanie-Susanne Stecher, Trude Steinsvik, Ymkje Stienstra, Birgitte Stiksrud, Eva Stolz, Amy Stone, Anca Streinu-Cercel, Adrian Streinu-Cercel, Geoff Strong, Ami Stuart, David Stuart, Richa Su, Decy Subekti, Gabriel Suen, Jacky Y. Suen, Prasanth Sukumar, Asfia Sultana, Charlotte Summers, Dubravka Supic, Deepashankari Suppiah, Magdalena Surovcová, Atie Suwarti, Andrey Svistunov, Sarah Syahrin, Augustina Sylverken, Konstantinos Syrigos, Jaques Sztajnbok, Konstanty Szuldrzynski, Shirin Tabrizi, Fabio S. Taccone, Lysa Tagherset, Shahdattul Mawarni Taib, Sara Taleb, Cheikh Talla, Jelmer Talsma, Renaud Tamisier, Maria Lawrensia Tampubolon, Kim Keat Tan, Yan Chyi Tan, Hiroyuki Tanaka, Taku Tanaka, Hayato Taniguchi, Huda Taqdees, Arshad Taqi, Coralie Tardivon, Yousef Tarek Kamal Mostafa, Ali Tarhabat, Pierre Tattevin, M Azhari Taufik, Hassan Tawfik, Tze Yuan Tee, João Teixeira, Sofia Tejada, Marie-Capucine Tellier, Sze Kye Teoh, Vanessa Teotonio, François Téoulé, Olivier Terrier, Nicolas Terzi, Hubert Tessier-Grenier, Adrian Tey, Alif Adlan Mohd Thabit, Anand Thakur, Zhang Duan Tham, Suvintheran Thangavelu, Elmi Theron, Vincent Thibault, Simon-Djamel Thiberville, Benoît Thill, Jananee Thirumanickam, Niamh Thompson, Shaun Thompson, Emma C. Thomson, David Thomson, Mathew Thorpe, Surain Raaj Thanga Thurai, Ryan S. Thwaites, Paul Tierney, Vadim Tieroshyn, Peter S. Timashev, Jean-François Timsit, Noémie Tissot, Fiona Toal, Jordan Zhien Yang Toh, Maria Toki, Kristian Tonby, Sia Loong Tonnii, Marta Torre, Antoni Torres, Margarida Torres, Rosario Maria Torres Santos-Olmo, Hernando Torres-Zevallos, Aboubacar Tounkara, Michael Towers, Fodé Amara Traoré, Tony Trapani, Cécile Tromeur, Ioannis Trontzas, Tiffany Trouillon, Jeanne Truong, Christelle Tual, Sarah Tubiana, Helen Tuite, Alexis F. Turgeon, Jean-Marie Turmel, Lance C.W. Turtle, Anders Tveita, Pawel Twardowski, Makoto Uchiyama, PG Ishara Udayanga, Andrew Udy, Roman Ullrich, Alberto Uribe, Asad Usman, Effua Usuf, Timothy M. Uyeki, Cristinava Vajdovics, Piero Valentini, Luís Val-Flores, Stijn Van de Velde, Marcel van den Berge, Machteld van der Feltz, Job van der Palen, Paul van der Valk, Nicky Van Der Vekens, Peter Van der Voort, Sylvie Van Der Werf, Laura van Gulik, Jarne Van Hattem, Carolien van Netten, Ilonka van Veen, Noémie Vanel, Henk Vanoverschelde, Michael Varrone, Shoban Raj Vasudayan, Charline Vauchy, Pavan Kumar Vecham, Shaminee Veeran, Aurélie Veislinger, Sebastian Vencken, Sara Ventura, Annelies Verbon, José Ernesto Vidal, César Vieira, Deepak Vijayan, Judit Villar, Pierre-Marc Villeneuve, Andrea Villoldo, Gayatri Vishwanathan, Benoit Visseaux, Hannah Visser, Chiara Vitiello, Manivanh Vongsouvath, Harald Vonkeman, Fanny Vuotto, Suhaila Abdul Wahab, Noor Hidayu Wahab, Nadirah Abdul Wahid, Marina Wainstein, Laura Walsh, Wan Fadzlina Wan Muhd Shukeri, Chih-Hsien Wang, Steve Webb, Katharina Weil, Tan Pei Wen, Hassi Wesam, Sanne Wesselius, T. Eoin West, Murray Wham, Bryan Whelan, Nicole White, Paul Henri Wicky, Aurélie Wiedemann, Surya Otto Wijaya, Keith Wille, Sue Willems, Bailey Williams, Patricia J. Williams, Virginie Williams, Jessica Wittman, Calvin Wong, Xin Ci Wong, Yew Sing Wong, Teck Fung Wong, Natalie Wright, Lim Saio Xian, Ioannis Xynogalas, Siti Rohani Binti Mohd Yakop, Masaki Yamazaki, Elizabeth Yarad, Yazdan Yazdanpanah, Nicholas Yee Liang Hing, Abdelrahman Yehia Mahmoud Abdelaal, Cécile Yelnik, Chian Hui Yeoh, Stephanie Yerkovich, Touxiong Yiaye, Toshiki Yokoyama, Hodane Yonis, Obada Yousif, Saptadi Yuliarto, Akram Zaaqoq, Marion Zabbe, Gustavo E. Zabert, Kai Zacharowski, Masliza Zahid, Maram Zahran, Nor Zaila Binti Zaidan, Maria Zambon, Miguel Zambrano, Alberto Zanella, Nurul Zaynah, Hiba Zayyad, Alexander Zoufaly, and David Zucman
Subjects: COVID-19, Non-respiratory symptoms, Respiratory symptoms, Risk factors, Mortality, Science (General), Q1-390, Social sciences (General), H1-99
Abstract: Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83–0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders.
Published: 2024
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5. Measurement of the inclusive isolated prompt photon cross-section in pp collisions at sqrt(s)= 7 TeV using 35 pb-1 of ATLAS data

Author: G. AAD, E. ABAT, B. ABBOTT, J. ABDALLAH, A. A. ABDELALIM, A. ABDESSELAM, O. ABDINOV, B. ABI, M. ABOLINS, H. ABRAMOWICZ, H. ABREU, E. ACERBI, B. S. ACHARYA, M. ACKERS, D. L. ADAMS, T. N. ADDY, J. ADELMAN, M. ADERHOLZ, C. ADORISIO, P. ADRAGNA, T. ADYE, S. AEFSKY, J. A. AGUILAR SAAVEDRA, M. AHARROUCHE, S. P. AHLEN, F. AHLES, A. AHMAD, H. AHMED, M. AHSAN, G. AIELLI, T. AKDOGAN, P. F. AKESSON, T. P. A. AKESSON, G. AKIMOTO, A. V. AKIMOV, A. AKTAS, M. S. ALAM, M. A. ALAM, J. ALBERT, S. ALBRAND, M. ALEKSA, I. N. ALEKSANDROV, M. ALEPPO, F. ALESSANDRIA, C. ALEXA, G. ALEXANDER, G. ALEXANDRE, T. ALEXOPOULOS, M. ALHROOB, M. ALIEV, G. ALIMONTI, J. ALISON, M. ALIYEV, P. P. ALLPORT, S. E. ALLWOOD SPIERS, J. ALMOND, A. ALOISIO, R. ALON, A. ALONSO, J. ALONSO, M. G. ALVIGGI, K. AMAKO, P. AMARAL, G. AMBROSINI, G. AMBROSIO, C. AMELUNG, V. V. AMMOSOV, A. AMORIM, G. AMOROS, N. AMRAM, C. ANASTOPOULOS, T. ANDEEN, C. F. ANDERS, K. J. ANDERSON, A. ANDREAZZA, V. ANDREI, M. L. ANDRIEUX, X. S. ANDUAGA, A. 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VORWERK, M. VOS, K. C. VOSS, R. VOSS, T. T. VOSS, J. H. VOSSEBELD, A. S. VOVENKO, N. VRANJES, M. VRANJES MILOSAVLJEVIC, V. VRBA, M. VREESWIJK, T. VU ANH, B. VUARIDEL, D. VUDRAGOVIC, R. VUILLERMET, I. VUKOTIC, A. WAANANEN, P. WAGNER, H. WAHLEN, J. WALBERSLOH, J. WALDER, R. WALKER, W. WALKOWIAK, R. WALL, S. WALSH, C. WANG, H. WANG, J. WANG, J. C. WANG, M. W. WANG, S. M. WANG, F. WAPPLER, A. WARBURTON, C. P. WARD, M. WARSINSKY, R. WASTIE, P. M. WATKINS, A. T. WATSON, M. F. WATSON, G. WATTS, S. WATTS, A. T. WAUGH, B. M. WAUGH, M. WEBEL, G. WEBER, J. WEBER, M. D. WEBER, M. WEBER, M. S. WEBER, P. WEBER, A. R. WEIDBERG, J. WEINGARTEN, C. WEISER, H. WELLENSTEIN, H. P. WELLISCH, P. S. WELLS, M. WEN, T. WENAUS, S. WENDLER, T. WENGLER, S. WENIG, N. WERMES, M. WERNER, P. WERNER, M. WERTH, U. WERTHENBACH, M. WESSELS, K. WHALEN, S. J. WHEELER ELLIS, S. P. WHITAKER, A. WHITE, M. J. WHITE, S. WHITE, S. R. WHITEHEAD, D. WHITESON, D. WHITTINGTON, F. WICEK, D. WICKE, F. J. WICKENS, W. WIEDENMANN, M. WIELERS, P. WIENEMANN, M. WIESMANN, C. WIGLESWORTH, L. A. M. WIIK, A. WILDAUER, M. A. WILDT, I. WILHELM, H. G. WILKENS, E. WILLIAMS, H. H. WILLIAMS, W. WILLIS, S. WILLOCQ, J. A. WILSON, M. G. WILSON, A. WILSON, I. WINGERTER SEEZ, F. WINKLMEIER, M. WITTGEN, E. WOEHRLING, M. W. WOLTER, H. WOLTERS, B. K. WOSIEK, J. WOTSCHACK, M. J. WOUDSTRA, K. WRAIGHT, C. WRIGHT, D. WRIGHT, B. WRONA, S. L. WU, X. WU, J. WUESTENFELD, E. WULF, R. WUNSTORF, B. M. WYNNE, L. XAPLANTERIS, S. XELLA, S. XIE, Y. XIE, D. XU, G. XU, N. XU, M. YAMADA, A. YAMAMOTO, K. YAMAMOTO, S. YAMAMOTO, T. YAMAMURA, J. YAMAOKA, T. YAMAZAKI, Y. YAMAZAKI, Z. YAN, H. YANG, S. YANG, U. K. YANG, Y. YANG, Z. YANG, W. M. YAO, Y. YAO, K. YARRADODDI, Y. YASU, J. YE, S. YE, M. YILMAZ, R. YOOSOOFMIYA, K. YORITA, H. YOSHIDA, R. YOSHIDA, C. YOUNG, S. P. YOUSSEF, D. YU, J. YU, J. YUAN, L. YUAN, A. YURKEWICZ, V. G. ZAETS, R. ZAIDAN, A. M. ZAITSEV, Z. ZAJACOVA, Y.O. K. ZALITE, V. ZAMBRANO, L. ZANELLO, P. ZARZHITSKY, A. ZAYTSEV, M. ZDRAZIL, C. ZEITNITZ, M. ZELLER, P. F. ZEMA, A. ZEMLA, C. ZENDLER, A. V. ZENIN, O. ZENIN, T. ZENIS, Z. ZENONOS, S. ZENZ, D. ZERWAS, G. ZEVI DELLA PORTA, Z. ZHAN, H. ZHANG, J. ZHANG, Q. ZHANG, X. ZHANG, L. ZHAO, T. ZHAO, Z. ZHAO, A. ZHEMCHUGOV, S. ZHENG, J. ZHONG, B. ZHOU, N. ZHOU, Y. ZHOU, C. G. ZHU, H. ZHU, Y. ZHU, X. ZHUANG, V. ZHURAVLOV, B. ZILKA, R. ZIMMERMANN, S. ZIMMERMANN, M. ZIOLKOWSKI, R. ZITOUN, L. ZIVKOVIC, V. V. ZMOUCHKO, G. ZOBERNIG, Y. ZOLNIEROWSKI, A. ZSENEI, M. ZUR NEDDEN, V. ZUTSHI, BERTIN, ANTONIO, BINDI, MARCELLO, CAFORIO, DAVIDE, DE CASTRO, STEFANO, DI SIPIO, RICCARDO, FABBRI, LAURA, FRANCHINI, MATTEO, MASSA, IGNAZIO GIACOMO, MENGARELLI, ALBERTO, MONZANI, SIMONE, PICCININI, MAURIZIO, RINALDI, LORENZO, SBARRA, CARLA, SBRIZZI, ANTONIO, SEMPRINI CESARI, NICOLA, VALENTINETTI, SARA, VILLA, MAURO, ZOCCOLI, ANTONIO, UAM. Departamento de Física Teórica, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire, Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institute of High Energy Physics (IHEP), Chinese Academy of Sciences [Changchun Branch] (CAS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), APC - Neutrinos, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), ATLAS, Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), G. AAD, E. ABAT, B. ABBOTT, J. ABDALLAH, A.A. ABDELALIM, A. ABDESSELAM, O. ABDINOV, B. ABI, M. ABOLINS, H. ABRAMOWICZ, H. ABREU, E. ACERBI, B.S. ACHARYA, M. ACKERS, D.L. ADAMS, T.N. ADDY, J. ADELMAN, M. ADERHOLZ, C. ADORISIO, P. ADRAGNA, T. ADYE, S. AEFSKY, J.A. AGUILAR-SAAVEDRA, M. AHARROUCHE, S.P. AHLEN, F. AHLES, A. AHMAD, H. AHMED, M. AHSAN, G. AIELLI, T. AKDOGAN, P.F. AKESSON, T.P.A. AKESSON, G. AKIMOTO, A.V. AKIMOV, A. AKTAS, M.S. ALAM, M.A. ALAM, J. ALBERT, S. ALBRAND, M. ALEKSA, I.N. ALEKSANDROV, M. ALEPPO, F. ALESSANDRIA, C. ALEXA, G. ALEXANDER, G. ALEXANDRE, T. ALEXOPOULOS, M. ALHROOB, M. ALIEV, G. ALIMONTI, J. ALISON, M. ALIYEV, P.P. ALLPORT, S.E. ALLWOOD-SPIERS, J. ALMOND, A. ALOISIO, R. ALON, A. ALONSO, J. ALONSO, M.G. ALVIGGI, K. AMAKO, P. AMARAL, G. AMBROSINI, G. AMBROSIO, C. AMELUNG, V.V. AMMOSOV, A. AMORIM, G. AMOROS, N. AMRAM, C. ANASTOPOULOS, T. ANDEEN, C.F. ANDERS, K.J. ANDERSON, A. ANDREAZZA, V. ANDREI, M.-L. ANDRIEUX, X.S. ANDUAGA, A. ANGERAMI, F. ANGHINOLFI, N. ANJOS, A. ANNOVI, A. ANTONAKI, M. ANTONELLI, S. ANTONELLI, J. ANTOS, B. ANTUNOVIC, F. ANULLI, S. AOUN, G. ARABIDZE, I. ARACENA, Y. ARAI, A.T.H. ARCE, J.P. ARCHAMBAULT, S. ARFAOUI, J.-F. ARGUIN, T. ARGYROPOULOS, E. ARIK, M. ARIK, A.J. ARMBRUSTER, K.E. ARMS, S.R. ARMSTRONG, O. ARNAEZ, C. ARNAULT, A. ARTAMONOV, D. ARUTINOV, M. ASAI, S. ASAI, R. ASFANDIYAROV, S. ASK, B. ASMAN, D. ASNER, L. ASQUITH, K. ASSAMAGAN, A. ASTBURY, A. ASTVATSATOUROV, B. ATHAR, G. ATOIAN, B. AUBERT, B. AUERBACH, E. AUGE, K. AUGSTEN, M. AUROUSSEAU, N. AUSTIN, G. AVOLIO, R. AVRAMIDOU, D. AXEN, C. AY, G. AZUELOS, Y. AZUMA, M.A. BAAK, G. BACCAGLIONI, C. BACCI, A.M. BACH, H. BACHACOU, K. BACHAS, G. BACHY, M. BACKES, E. BADESCU, P. BAGNAIA, Y. BAI, D.C. BAILEY, T. BAIN, J.T. BAINES, O.K. BAKER, M.D. BAKER, S. BAKER, F. BALTASAR DOS SANTOS PEDROSA, E. BANAS, P. BANERJEE, S. BANERJEE, D. BANFI, A. BANGERT, V. BANSAL, S.P. BARANOV, S. BARANOV, A. BARASHKOU, T. BARBER, E.L. BARBERIO, D. BARBERIS, M. BARBERO, D.Y. BARDIN, T. BARILLARI, M. BARISONZI, T. BARKLOW, N. BARLOW, B.M. BARNETT, R.M. BARNETT, A. BARONCELLI, M. BARONE, A.J. BARR, F. BARREIRO, J. BARREIRO GUIMARAES DA COSTA, P. BARRILLON, V. BARTHELD, H. BARTKO, R. BARTOLDUS, D. BARTSCH, R.L. BATES, S. BATHE, L. BATKOVA, J.R. BATLEY, A. BATTAGLIA, M. BATTISTIN, G. BATTISTONI, F. BAUER, H.S. BAWA, M. BAZALOVA, B. BEARE, T. BEAU, P.H. BEAUCHEMIN, R. BECCHERLE, N. BECERICI, P. BECHTLE, G.A. BECK, H.P. BECK, M. BECKINGHAM, K.H. BECKS, A.J. BEDDALL, A. BEDDALL, V.A. BEDNYAKOV, C. BEE, M. BEGEL, S. BEHAR HARPAZ, P.K. BEHERA, M. BEIMFORDE, G.A.N. BELANGER, C. BELANGER-CHAMPAGNE, B. BELHORMA, P.J. BELL, W.H. BELL, G. BELLA, L. BELLAGAMBA, F. BELLINA, G. BELLOMO, M. BELLOMO, A. BELLONI, K. BELOTSKIY, O. BELTRAMELLO, A. BELYMAM, S. BEN AMI, O. BENARY, D. BENCHEKROUN, C. BENCHOUK, M. BENDEL, B.H. BENEDICT, N. BENEKOS, Y. BENHAMMOU, G.P. BENINCASA, D.P. BENJAMIN, M. BENOIT, J.R. BENSINGER, K. BENSLAMA, S. BENTVELSEN, M. BERETTA, D. BERGE, E. BERGEAAS KUUTMANN, N. BERGER, F. BERGHAUS, E. BERGLUND, J. BERINGER, K. BERNARDET, P. BERNAT, R. BERNHARD, C. BERNIUS, T. BERRY, A. BERTIN, F. BERTINELLI, S. BERTOLUCCI, M.I. BESANA, N. BESSON, S. BETHKE, R.M. BIANCHI, M. BIANCO, O. BIEBEL, M. BIERI, J. BIESIADA, M. BIGLIETTI, H. BILOKON, M. BINDER, M. BINDI, S. BINET, A. BINGUL, C. BINI, C. BISCARAT, R. BISCHOF, U. BITENC, K.M. BLACK, R.E. BLAIR, O. BLANCH, J.-B. BLANCHARD, G. BLANCHOT, C. BLOCKER, J. BLOCKI, A. BLONDEL, W. BLUM, U. BLUMENSCHEIN, C. BOARETTO, G.J. BOBBINK, A. BOCCI, D. BOCIAN, R. BOCK, M. BOEHLER, M. BOEHM, J. BOEK, N. BOELAERT, S. BOSER, J.A. BOGAERTS, A. BOGOUCH, C. BOHM, J. BOHM, V. BOISVERT, T. BOLD, V. BOLDEA, A. BOLDYREV, V.G. BONDARENKO, M. BONDIOLI, R. BONINO, M. BOONEKAMP, G. BOORMAN, M. BOOSTEN, C.N. BOOTH, P.S.L. BOOTH, P. BOOTH, J.R.A. BOOTH, S. BORDONI, C. BORER, K. BORER, A. BORISOV, G. BORISSOV, I. BORJANOVIC, S. BORRONI, K. BOS, D. BOSCHERINI, M. BOSMAN, H. BOTERENBROOD, D. BOTTERILL, J. BOUCHAMI, J. BOUDREAU, E.V. BOUHOVA-THACKER, C. BOULAHOUACHE, C. BOURDARIOS, A. BOVEIA, J. BOYD, B.H. BOYER, I.R. BOYKO, N.I. BOZHKO, I. BOZOVIC-JELISAVCIC, S. BRACCINI, J. BRACINIK, A. BRAEM, E. BRAMBILLA, P. BRANCHINI, G.W. BRANDENBURG, A. BRANDT, G. BRANDT, O. BRANDT, U. BRATZLER, B. BRAU, J.E. BRAU, H.M. BRAUN, S. BRAVO, B. BRELIER, J. BREMER, R. BRENNER, S. BRESSLER, D. BRETON, N.D. BRETT, P.G. BRIGHT-THOMAS, D. BRITTON, F.M. BROCHU, I. BROCK, R. BROCK, T.J. BRODBECK, E. BRODET, F. BROGGI, C. BROMBERG, G. BROOIJMANS, W.K. BROOKS, G. BROWN, E. BRUBAKER, P.A. BRUCKMAN DE RENSTROM, D. BRUNCKO, R. BRUNELIERE, S. BRUNET, A. BRUNI, G. BRUNI, M. BRUSCHI, T. BUANES, F. BUCCI, J. BUCHANAN, N.J. BUCHANAN, P. BUCHHOLZ, A.G. BUCKLEY, I.A. BUDAGOV, B. BUDICK, V. BUSCHER, L. BUGGE, D. BUIRA-CLARK, E.J. BUIS, F. BUJOR, O. BULEKOV, M. BUNSE, T. BURAN, H. BURCKHART, S. BURDIN, T. BURGESS, S. BURKE, E. BUSATO, P. BUSSEY, C.P. BUSZELLO, F. BUTIN, B. BUTLER, J.M. BUTLER, C.M. BUTTAR, J.M. BUTTERWORTH, T. 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ZUR NEDDEN, and V. ZUTSHI
Subjects: Standard Model, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Física, ddc:500.2, ATLAS, Photon, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), HADRON-HADRON COLLISIONS, INCLUSIVE DIFFERENTIAL CROSS SECTION, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], High Energy Physics::Experiment, Física nuclear, LHC, Nuclear Experiment, Particle Physics - Experiment
Abstract: A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy sqrt(s) = 7 TeV is presented. The measurement covers the pseudorapidity ranges |eta, 7 pages plus author list (18 pages total), 2 figures, 4 tables, final version published in Physics Letters B
Published: 2011

6. Models for Stress-Phase Transformation Couplings in Metallic Alloys

Author: E. Gautier, Sabine Denis, and P. Archambault
Subjects: Materials science, Nucleation, chemistry.chemical_element, Thermodynamics, Welding, Isothermal process, law.invention, Thermoelastic damping, chemistry, law, Aluminium, Thermal, Hardening (metallurgy), Softening
Abstract: This chapter discusses the models for stress-phase transformation couplings in metallic models.v The models described in the chapter, which concern phase transformation kinetics and thermomechanical behavior, is used for many steels and high-strength aluminium alloys submitted to various thermal histories (heating, cooling, isothermal holding) and to stress states that lead to small plastic strains (a few percent). Typical applications are the modeling of heat treatment processes and also welding processes. A global approach based on the Johnson Mehl Avrami formalism is developed that assumes an additivity principle, or an approach that explicitly includes nucleation and growth laws. The thermomechanical behavior of the material during the phase change is described by phenomenological behavior laws that include the thermoelastic and plastic-viscoplastic behavior of the stable multiphase material and the effect of the phase transformations. For precipitation at very small volume fractions, the approach through mixture laws is no longer valid, and a model describing both mechanical softening due to heterogeneous precipitation and hardening due to homogeneous precipitation is proposed.
Published: 2001

7. CONTRIBUTORS

Author: ELIAS C. AIFANTIS, HOLM ALTENBACH, P. ARCHAMBAULT, ELLEN M. ARRUDA, C. BATHIAS, ZDENEK P. BAZANT, AHMED BENALLAL, ALBRECHT BERTRAM, YVES BERTHIER, B.J. BESSON, J.F. BESSELING, M. BERVEILLER, RENÉ BILLARDON, SOL R. BODNER, MARY C. BOYCE, YVES BRECHET, DAVID BROEK, HUY DUONG BUI, ALAIN BURR, ESTEBAN P. BUSSO, GEORGES CAILLETAUD, VALTER CARVELLI, SERGE CESCOTTO, J.L. CHABOCHE, A.H.C. CHAN, C.L. CHOW, TRAIAN CICONE, N.D. CRISTESCU, OLIVIER COUSSY, STEPHEN C. COWIN, CHRISTIAN CUNAT, PATRICK DANGLA, FÉLIX DARVE, YANNIS F. DAFALIAS, S. DENIS, CHANDRA S. DESAI, RODRIGUE DESMORAT, MARTA DRAGON-LOUISET, DANIEL C. DRUCKER, GEORGE J. DVORAK, L. DUCHÉNE, FERNAND ELLYIN, F.D. FISCHER, DOMINIQUE FRANÇOIS, JEAN FRÊNE, E. GAUTIER, A. GODINAS, DIETMAR GROSS, ANNE MARIE HABRAKEN, JEAN-MARC HAUDIN, D.R. HAYHURST, FRANÇOIS HILD, LAURENT HIRSINGER, K. HO, GERHARD A. HOLZAPFEL, KOZO IKEGAMI, TATSUO INOUE, HIROMASA ISHIKAWA, HENRIK MYHRE JENSEN, KOJI KATO, JANUSZ R. KLEPACZKO, W.G. KNAUSS, DUSAN KRAJCINOVIC, E. KREMPL, TADEUSZ KURTYKA, PIERRE LADEVÈZE, FREDERICK A. LECKIE, J-B. LEBLOND, JEAN LEMAITRE, GIULIO MAIER, DIDIER MARQUIS, MAJID T. MANZARI, JACKY MAZARS, FREDERIC MESLIN, ALAIN MOLINARI, BERNARD MONASSE, HAEL MUGHRABI, N. STALIN-MULLER, Z. MRÓZ, SUMIO MURAKAMI, ROBERTO NOVA, A. NEEDLEMAN, SIA NEMAT-NASSER, R.W. OGDEN, NOBUTADA OHNO, J. URGEN OLSCHEWSKI, FLORENCE OSSART, M. PASTOR, PIOTR PERZYNA, GILLES PIJAUDIER-CABOT, A. PINEAU, ARNAUD POITOU, RACHID RAHOUADJ, MICHEL RAOUS, GILLES ROUSSELIER, J.W. RUDNICKI, KATSUHIKO SASAKI, A.R. SAVKOOR, R.A. SCHAPERY, ROBERT SCHIRRER, SABINE M. SCHLOGL, B.A. SCHREFLER, L. SIMONI, PETROS SOFRONIS, DARRELL SOCIE, CLAUDE STOLZ, PIERRE M. SUQUET, ALBERTO TALIERCIO, EIICHI TANAKA, MASATAKA TOKUDA, V. TVÉRGAARD, K. DANG VAN, ERIK VAN DER GIESSEN, P. VAN HOUTTE, J.G.M. VAN MIER, IOANNIS VARDOULAKIS, GEORGE Z. VOYIADJIS, MICHAEL WAUTERS, YONG WEI, J.R. WILLIS, A. TOSHIMITSU YOKOBORI, TAKEO YOKOBORI, XING ZHANG, JUN ZHAO, Y. ZHU, O.C. ZIENKIEWICZ, and MICHA ŻYCZKOWSKI
Published: 2001

8. Decomposition de la Solution Solide de l'Alliage 7075 au Cours de la Trempe — Effet sur le Durcissement par Precipitation

Author: G. Beck, P. Archambault, and F. Moreaux et
Abstract: RESUME Dans le cas d'alliages de type AZ 5 GU (7075) la decomposition de la solution solide est suivie au cours de refroidissements de trempe pilotes en temps reel. Pendant ce refroidissement plusieurs modes de precipitation sont actives. L'ampleur de chaque phenomene est liee a l'etat de sursaturation de la solution solide et, par suite, a l'evolution thermique du metal. L'influence de la sursaturation obtenue en fin de trempe sur le durcissement de l'alliage lors de revenus isothermes est egalement etudiee. Des courbes d'isodurete sont tracees pour differents refroidissements de trempe. La representation des resultats obtenus pour de nombreuses conditions de traitement, dans un diagramme d'Arrhenius, revele l'influence de la sursaturation initiale sur la cinetique de durcissement de l'alliage au revenu.
Published: 1985

9. Remotely sensed surface water variations during drought and deluge conditions in a Northern Great Plains terminal lake basin

Author: Alexis L. Archambault, Taufique H. Mahmood, Paul E. Todhunter, and Scott F. Korom
Subjects: Northern Great Plain (NGP), Total water area (TWA), Permanent water area (PWA), Seasonal water area (SWA), Physical geography, GB3-5030, Geology, QE1-996.5
Abstract: Study region: Northern Great Plains (NGP) region, North Dakota, USA Study focus: Understanding climate change impacts on surface water dynamics of permanent and seasonal water areas under drought to deluge conditions in the Devils Lake Basin (DLB) utilizing a high-resolution global surface water dataset (GSWD). New hydrologic insights: Four phases of dry and wet conditions were experienced in the DLB during the 1990–2018 study period: wetting (1990–1999), stable (2000–2003), recent wetting (2004–2013) and recent drying (2014–2018). A substantial transition from bare land to permanent and seasonal water area is observed during the wetting period (1990–99) while during the stable period (2000–2003), changes are barely observed despite NGP-wide drought. In the recent wetting period (2004–2013), a noticeable gain of permanent water from seasonal and bare land is observed. During the recent drying period (2014–2018), a significant loss of seasonal water area to bare land occurred. The difference between the spring and summer surface water areas is high during the recent wetting period (e.g., 2009, 2011, 2013), but much lower as the DLB approaches a drought condition. The inter-annual and intra-annual water dynamics of permanent and seasonal water areas show different rates of change and varying hydrological lags to changing hydroclimatic drivers and these changes are sensitive to basin antecedent conditions.
Published: 2023
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10. RAMPVIS: Answering the challenges of building visualisation capabilities for large-scale emergency responses

Author: M. Chen, A. Abdul-Rahman, D. Archambault, J. Dykes, P.D. Ritsos, A. Slingsby, T. Torsney-Weir, C. Turkay, B. Bach, R. Borgo, A. Brett, H. Fang, R. Jianu, S. Khan, R.S. Laramee, L. Matthews, P.H. Nguyen, R. Reeve, J.C. Roberts, F.P. Vidal, Q. Wang, J. Wood, and K. Xu
Subjects: Data visualisation, Visual analytics, Pandemic responses, COVID-19, Model development, Infectious and parasitic diseases, RC109-216
Abstract: The effort for combating the COVID-19 pandemic around the world has resulted in a huge amount of data, e.g., from testing, contact tracing, modelling, treatment, vaccine trials, and more. In addition to numerous challenges in epidemiology, healthcare, biosciences, and social sciences, there has been an urgent need to develop and provide visualisation and visual analytics (VIS) capacities to support emergency responses under difficult operational conditions. In this paper, we report the experience of a group of VIS volunteers who have been working in a large research and development consortium and providing VIS support to various observational, analytical, model-developmental, and disseminative tasks. In particular, we describe our approaches to the challenges that we have encountered in requirements analysis, data acquisition, visual design, software design, system development, team organisation, and resource planning. By reflecting on our experience, we propose a set of recommendations as the first step towards a methodology for developing and providing rapid VIS capacities to support emergency responses.
Published: 2022
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11. Concurrent pulmonary coccidioidomycosis and immunoglobulin A vasculitis with hemorrhagic bullae

Author: Logan J. Archambault, DO, Joyce Y. Chen, BS, Robert A. Obeid, MD, Hannah E. Hill, MD, David J. DiCaudo, MD, and Krystal Renszel, DO, MS
Subjects: hemorrhagic bullous lesions, Henoch-Schönlein purpura, IgA vasculitis, pulmonary coccidioidomycosis, Dermatology, RL1-803
Published: 2021
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12. Employment Outcomes for Canadian Radiation Oncology Graduates: 2020 Assessment and Longitudinal Trends

Author: Che Hsuan David Wu, MD, Nauman Malik, MD, Michael Kim, MD, Teri Stuckless, MD, Ross Halperin, MD, Jean Archambault, MD, Robert Thompson, MD, Jolie Ringash, MD, Michael Brundage, MD, and Shaun K. Loewen, PhD, MD
Subjects: Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Purpose: Canadian radiation oncology (RO) trainees have experienced employment challenges after residency training. The present study was conducted to evaluate current employment trends and perform comparisons to prior reported assessments. Methods and Materials: A survey was administered to all 13 Canadian RO program directors requesting the employment status and location of their graduates during the past 3 years, and their perceptions on graduates’ employment challenges. Visa trainees were excluded. Findings were compared with surveys performed in 2014, 2016, and 2018. Results: The response rate from RO program directors was 100%. There were 77 graduates identified who completed their residency training between 2017 and 2020. All had known employment status and location. Two (17%) 2020 graduates, 16 (84%) 2019 graduates, 17 (81%) 2018 graduates, and 24 (100%) 2017 graduates had staff employment. Of the 59 graduates with staff positions, 86% were in Canada. Some graduates (28%) obtained staff or locum employment in a province other than their training program. The proportion of graduates obtaining staff positions 1 year after residency increased to 84% from 46%-48% in prior assessments. Most program directors (62%) did not perceive any difficulties with their graduates finding staff employment or trainees transferring to training programs in other disciplines owing to perceived workforce challenges. Conclusions: Compared with 3 prior employment outcome assessments, this study observed a higher proportion of graduates with staff positions in Canada, fewer total graduates, fewer graduates seeking staff employment or in fellowship positions, and a trend for fewer graduates seeking employment or fellowships abroad. These findings support the view that the Canadian RO job market continues to improve. Although employment challenges for newly certified, Canadian-trained radiation oncologists still exist, national corrective measures to regulate resident intake in 2011 appear to have had a positive effect on the employment outcomes of recent Canadian RO graduates.
Published: 2022
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13. Impacts of antibiotic reduction strategies on zootechnical performances, health control, and Eimeria spp. excretion compared with conventional antibiotic programs in commercial broiler chicken flocks

Author: Eric Parent, Marie Archambault, Robert J. Moore, and Martine Boulianne
Subjects: antibiotic reduction, broiler, intestinal health, zootechnical performance, Eimeria spp, Animal culture, SF1-1100
Abstract: Increasing efforts have been made in recent years to reduce antimicrobial use in animal production. The objective of this prospective study was to evaluate, in commercial broiler chicken farms, 2 antibiotic reduction strategies that eliminated the use of antibiotics important for human medicine, in comparison with the conventional use of antibiotics. On 7 broiler chicken farms, a house was allocated to the antibiotic reduction treatments for 6 consecutive flocks, whereas a similar house on the same premises was assigned to the conventional use of antibiotics (CONV) for 6 consecutive flocks. The antibiotic reduction strategies consisted of continuous in-feed use of ionophores (TX1) and continuous in-feed use of ionophores with butyric acid (TX2). In the 84 flocks, zootechnical performance was recorded, lesion scoring at 21 and 28 D of age was performed, and fecal samples were recovered during grow out for Eimeria spp. oocysts counts. There was no statistical difference between TX1, TX2, and CONV for weights at slaughter, feed conversion ratios, average daily gains, age at slaughter, total mortalities, and condemnations. The probability of identifying oocysts in the fecal samples significantly increased with the age of the flock, but there was no significant treatment effect between 7 and 16 D of age. At 19 D of age, the probability of a sample containing oocysts was higher in TX1 than in CONV, but TX2 was not statistically different from TX1 and CONV. Predicted oocysts per gram in CONV flocks were significantly lower between 22 and 34 D of age than in TX1 and TX2 flocks, whereas there were no significant differences between TX1 and TX2 for all ages. Lesion scoring of the gastrointestinal system showed no differences for coccidiosis scores between TX1, TX2, and CONV. No lesions of necrotic enteritis were observed. In conclusion, it was possible to adequately control intestinal diseases and maintain zootechnical performances by relying exclusively on ionophores, when compared with broiler chicken flocks using standard shuttle programs with antibiotic growth promoters.
Published: 2020
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14. Ecosystem-Based Quality Index in a harbor bay: Assessing the status of a heterogeneous system in a functional framework at a local scale

Author: Filippo Ferrario, Ladd E. Johnson, Christopher W. McKindsey, and Philippe Archambault
Subjects: Environmental management, Functional group, Coastal, Environmental quality, Stressors, R package, Ecology, QH540-549.5
Abstract: The assessment of natural ecosystem status is a fundamental premise to enable environmental management at local scales to maintain ecosystem functioning, services and resilience. Ecologists have developed many biological and environmental indices to inform and support environmental management and policies. To promote efficient use of resources, existing indices would ideally be informative for the widest geographic extent to avoid the development of new but redundant indices. The Ecosystem-Based Quality Index (EBQI), developed for the Mediterranean Sea, may be adaptable to other ecosystems due to its functional approach being closer to a methodological framework than a specialized index.We investigated the adaptability of EBQI beyond its original geographical setting and its applicability to a predefined location rather than a predefined ecosystem. We propose a workflow to apply EBQI to areas without a priori well-defined ecosystems: the shallow subtidal coastal areas of Baie des Sept Îles (Gulf of St. Lawrence, Canada), a major industrial port where the seafloor ranges from soft to mixed substrata (i.e., boulders and gravel in a soft-bottom matrix), creating ecosystem heterogeneity where species typical of different habitats often co-occur. We then tested the index for the assessment of this ecosystem with an explicit consideration of the ecosystem heterogeneity in shallow areas, typically unaccounted for by other indices. Using field sampling and a literature review, we showed that the EBQI can be implemented in areas where little prior information about a given ecosystem is available. Our EBQI implementation, shGSL-EBQI (shallow heterogeneous Gulf of St. Lawrence-EBQI), provided ecosystem status classifications that were robust and consistent with available environmental assessments in the area. We then showed that shGSL-EBQI relates to multiple environmental and anthropogenic drivers and suggest approaches to limit the effect of confounding environmental gradients. Finally, we discuss the potential applicability of shGSL-EBQI to other regions of the Gulf of St. Lawrence and provide advice on how a coastal monitoring initiative could facilitate widespread adoption of EBQI in Canada.As efforts to base future development on sustainability through ecosystem-based management increase both in Canada and internationally, we demonstrate that EBQI is well suited to the Canadian context and thus likely more generally in other jurisdictions.
Published: 2021
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15. Exploring the limits of complexity: A survey of empirical studies on graph visualisation

Author: Vahan Yoghourdjian, Daniel Archambault, Stephan Diehl, Tim Dwyer, Karsten Klein, Helen C. Purchase, and Hsiang-Yun Wu
Subjects: Information technology, T58.5-58.64
Abstract: For decades, researchers in information visualisation and graph drawing have focused on developing techniques for the layout and display of very large and complex networks. Experiments involving human participants have also explored the readability of different styles of layout and representations for such networks. In both bodies of literature, networks are frequently referred to as being ‘large’ or ‘complex’, yet these terms are relative. From a human-centred, experiment point-of-view, what constitutes ‘large’ (for example) depends on several factors, such as data complexity, visual complexity, and the technology used. In this paper, we survey the literature on human-centred experiments to understand how, in practice, different features and characteristics of node–link diagrams affect visual complexity. Keywords: Graph visualisation, Network visualisation, node–link diagrams, Cognitive scalability, Evaluations, Empirical studies
Published: 2018
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16. Guideline for testosterone recovery in localized prostate cancer treated with different ADT duration: Long-term data from two prospective randomized trials

Author: A. Nabid, N. Carrier, A-G. Martin, B. Bahoric, D. Wilke, E. Vigneault, F. Vincent, J-P. Bahary, M-A. Brassard, M. Duclos, P. Vavassis, R. Bettahar, R. Archambault, S. Vass, T.V. Nguyen, and L. Souhami
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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17. Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability

Author: Laila Shehata, Daniel P. Maurer, Anna Z. Wec, Asparouh Lilov, Elizabeth Champney, Tingwan Sun, Kimberly Archambault, Irina Burnina, Heather Lynaugh, Xiaoyong Zhi, Yingda Xu, and Laura M. Walker
Subjects: Biology (General), QH301-705.5
Abstract: Summary: Monoclonal antibodies (mAbs) have recently emerged as one of the most promising classes of biotherapeutics. A potential advantage of B cell-derived mAbs as therapeutic agents is that they have been subjected to natural filtering mechanisms, which may enrich for B cell receptors (BCRs) with favorable biophysical properties. Here, we evaluated 400 human mAbs for polyreactivity, hydrophobicity, and thermal stability using high-throughput screening assays. Overall, mAbs derived from memory B cells and long-lived plasma cells (LLPCs) display reduced levels of polyreactivity, hydrophobicity, and thermal stability compared with naive B cell-derived mAbs. Somatic hypermutation (SHM) is inversely associated with all three biophysical properties, as well as BCR expression levels. Finally, the developability profiles of the human B cell-derived mAbs are comparable with those observed for clinical mAbs, suggesting their high therapeutic potential. The results provide insight into the biophysical consequences of affinity maturation and have implications for therapeutic antibody engineering and development. : Shehata et al. analyze the biophysical properties of human antibodies derived from multiple B cell subsets and find that somatic hypermutation is associated with increased antibody specificity but diminished conformational stability. The results provide insight into the biophysical consequences of affinity maturation and have implications for antibody discovery and engineering. Keywords: B cells, monoclonal antibodies, developability, polyreactivity, hydrophobicity, conformational stability
Published: 2019
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18. Examination of bile acid negative feedback regulation in rats.

Author: R A Davis, C A Musso, M Malone-McNeal, G R Lattier, P M Hyde, J Archambault-Schexnayder, and M Straka
Subjects: Biochemistry, QD415-436
Abstract: Recent data obtained using cultured rat hepatocytes showed that bile acids do not inhibit bile acid synthesis, whereas cholesterol concentrations vary in parallel with bile acid synthesis (Davis et al. (1983. J. Biol. Chem. 258: 4079-4082). This led us to re-evaluate in vivo experiments upon which the consensus that bile acid synthesis is primarily regulated by bile acid ''negative feedback'' is based. Infusion of taurocholate into either the jugular vein or duodenum of bile-diverted rats stimulated biliary cholesterol secretion and bile flow, but it did not inhibit bile acid synthesis. The lack of an inhibitory effect was evident using several different infusion rates of taurocholate. Even at the greatest rate of taurocholate infusion (25 mumol/(100 g.hr] there was no significant inhibition of bile acid synthesis. In contrast, infusing mevinolin (1 mg/hr), a potent competitive inhibitor of HMG-CoA reductase, almost completely inhibited bile acid synthesis and biliary cholesterol secretion. Since mevinolin did not affect bile flow, these results cannot be ascribed to bile secretory failure. Thus, while these studies suggest that taurocholate may not regulate bile acid synthesis directly via negative feedback, cholesterol is likely to act as a positive effector of bile acid synthesis.
Published: 1988
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19. [Patients' experience of neoplasia care by their general practitioner. Qualitative study of case histories].

Author: Frêche B, Brillard R, Brenot A, Archambault P, and Poupin E
Subjects: Humans, Male, Female, Middle Aged, General Practitioners psychology, Neoplasms therapy, Neoplasms psychology, Aged, Patient Satisfaction, Physician's Role, Primary Health Care, General Practice, Truth Disclosure, Adult, Qualitative Research, Physician-Patient Relations
Abstract: Background: Little research has been done on the follow-up of patients in the active phase of treatment in primary care. This study aimed to build up a corpus of authentic clinical situations and carry out an inductive analysis of the data., Method: Research in two stages: case study and qualitative analysis of verbatims. The authors conducted individual interviews using an interview guide. The questions targeted their experiences, focusing on their relationship with their general practitioner., Results: Six themes were identified. The announcement of the diagnosis was a key moment. Patients emphasised their general practitioner's responsiveness and coordination, and stressed his involvement. They consulted him regularly during the active phase of treatment, and asked for information. They felt confident. The need to facilitate access to the general practitioner was noted, particularly in the event of a real or perceived emergency., Discussion: The increase in the prevalence and incidence of cancer means that general practitioners need to be heavily involved. The authorities are advocating a strengthening of the general practitioner's "pivotal role", without clearly defining it. A perceived lack of skills may be an obstacle to general practitioner involvement. Training in cancer during the 3rd cycle of general medical studies is inadequate. By compiling and analysing a corpus of cases, it would be possible to redefine the training objectives and list the skills required to manage cancer patients., (Copyright © 2024 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.)
Published: 2024
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20. The Impact of Advance Care Planning on Healthcare Professionals' Well-being: A Systematic Review.

Author: Gomes Souza L, Bouba DA, Corôa RC, Dofara SG, Robitaille V, Blanchette V, Kastner K, Bergeron F, Guay-Bélanger S, Izumi SS, Totten AM, Archambault P, and Légaré F
Subjects: Humans, Delivery of Health Care, Palliative Care methods, Advance Care Planning, Health Personnel psychology
Abstract: Context: Advance care planning (ACP) improves care for patients with chronic illnesses and reduces family stress. However, the impact of ACP interventions on healthcare professionals' well-being remains unknown., Objective: To systematically review the literature evaluating the impact of ACP interventions on healthcare professionals' well-being., Methods: We followed the Joanna Briggs Institute methodology for systematic reviews and registered the protocol in PROSPERO (CRD42022346354). We included primary studies in all languages that assessed the well-being of healthcare professionals in ACP interventions. We excluded any studies on ACP in psychiatric care and in palliative care that did not address goals of care. Searches were conducted on April 4, 2022, and March 6, 2023 in Embase, CINAHL, Web of Science, and PubMed. We used the Mixed Methods Appraisal Tool for quality analysis. We present results as a narrative synthesis because of their heterogeneity., Results: We included 21 articles published in English between 1997 and 2021 with 17 published after 2019. All were conducted in high-income countries, and they involved a total of 1278 participants. Three reported an interprofessional intervention and two included patient partners. Studies had significant methodological flaws but most reported that ACP had a possible positive impact on healthcare professionals' well-being., Conclusion: This review is the first to explore the impact of ACP interventions on healthcare professionals' well-being. ACP interventions appear to have a positive impact, but high-quality studies are scarce. Further research is needed, particularly using more rigorous and systematic methods to implement interventions and report results., (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
Published: 2024
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21. Quality of patient decision aids to support the public making COVID-19 decisions: An online environmental scan.

Author: Kiss A, Zhang Q, Carley M, Smith M, Légaré F, Archambault P, and Stacey D
Subjects: Humans, Aged, COVID-19 Vaccines, Decision Making, Patient Participation, Decision Support Techniques, COVID-19 epidemiology
Abstract: Objective: To identify and appraise the quality of COVID-19 patient decision aids (PtDAs)., Methods: We conducted an environmental scan of online publicly available COVID-19 PtDAs. Two reviewers independently searched and extracted data. We calculated median International Patient Decision Aid Standards (IPDAS) scores and proportion scoring > 70% on Patient Education Materials Information Tool (PEMAT) adequate for understandability and actionability., Results: Of 876 resources identified, 12 were PtDAs. Decisions focused on initial COVID-19 vaccination series (n = 9), location of care for elderly (n = 2), and social distancing (n = 1). All 12 PtDAs were written materials and two had accompanying videos. The median IPDAS score minimizing risk of biased decisions was 4 of 6 items (IQR 1, range 2-4). For PEMAT, 92% had adequate for understandability and none for actionability., Conclusions: We identified few online publicly available COVID-19 PtDAs and none were about COVID-19 vaccination boosters or treatment. PtDAs scored poorly on actionability and none met all IPDAS criteria for minimizing risk of biased decisions., Practice Implications: PtDA developers for COVID-19 and future pandemics should ensure their PtDAs meet all IPDAS criteria for minimizing risk of bias, have adequate scores for actionability, and are disseminated in the A to Z inventory., Competing Interests: Declaration of Competing Interest None., (Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
Published: 2023
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22. Phycotoxins in bivalves from the western Canadian Arctic: The first evidence of toxigenicity.

Author: Pućko M, Rourke W, Hussherr R, Archambault P, Eert J, Majewski AR, Niemi A, Reist J, and Michel C
Subjects: Animals, Marine Toxins toxicity, Ecosystem, Chlorophyll A, Canada, Phytoplankton, Bivalvia, Diatoms
Abstract: This study presents the first evidence that a diverse suite of phycotoxins is not only being actively produced by the toxigenic algal communities in the Canadian Arctic waters, but is also entering the marine food web. We detected measurable amounts of Amnesic Shellfish Toxins (ASTs) and Paralytic Shellfish Toxins (PSTs), as well as trace amounts of other lipophilic toxin groups including pectenotoxins, yessotoxins, and cyclic imines, in bivalves collected from the Canadian Beaufort Sea in 2014 and 2018. There appear to be species-specific differences in accumulation and retention of AST by Arctic bivalves, with significantly higher concentrations recorded in Nuculanidae than Propeamussiidae, likely reflecting physiological and allometric differences. We further confirm the omnipresence of potentially toxic taxonomically-versatile phytoplankton communities in the western Canadian Arctic comprising Pseudo-nitzschia delicatissima group, P. obtusa, Dinophysis acuminata, Prorocentrum minimum, Alexandrium tamarense, and Gymnodinium spp. Although measurements of actual toxicity levels and profiles of these species at the time of sampling fall outside of the scope of this study, we show that high abundance and competitive success of known AST-producers, Pseudo-nitzschia spp., are possible in Canadian Arctic waters. In 2014, a strong dominance of Pseudo-nitzschia spp. was observed at a few shallow coastal stations, representing nearly 40% of the total phytoplankton cell abundances with > 10 6 cells/L at the depth of maximum chlorophyll a. We further describe oceanographic conditions conducive to high abundances of toxin-producing algae, indicating that temperature is likely a key factor. Even though measured AST and PST concentrations in bivalve tissue remained well below the Health Canada's levels at which monitored fisheries would close, i.e., 5% and 4%, respectively, their presence demonstrate that phycotoxin accumulation is occurring in food webs of the Canadian Beaufort Sea. Yet, the phycotoxin production controls and trophic transfer mechanisms remain unknown. Canadian Arctic marine ecosystems are rapidly changing and temperatures are expected to continue to increase. Given that these changes simultaneously affect multiple, and often co-occurring, species of primary producers, adaptive capacity is likely to play an important role in the structure of phytoplankton communities in the Canadian Arctic., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Crown Copyright © 2023. Published by Elsevier B.V. All rights reserved.)
Published: 2023
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23. Patient-reported health outcomes of SARS-CoV-2-tested patients presenting to emergency departments: a propensity score-matched prospective cohort study.

Author: Bola R, Sutherland J, Murphy RA, Leeies M, Grant L, Hayward J, Archambault P, Graves L, Rose T, and Hohl C
Subjects: Humans, Retrospective Studies, Propensity Score, Prospective Studies, Canada, Outcome Assessment, Health Care, SARS-CoV-2, COVID-19
Abstract: Objective: This study aimed to compare the long-term physical and mental health outcomes of matched severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and SARS-CoV-2-negative patients controlling for seasonal effects., Study Design: This was a retrospective cohort study., Methods: This study enrolled patients presenting to emergency departments participating in the Canadian COVID-19 Emergency Department Rapid Response Network. We enrolled consecutive eligible consenting patients who presented between March 1, 2020, and July 14, 2021, and were tested for SARS-CoV-2. Research assistants randomly selected four site and date-matched SARS-CoV-2-negative controls for every SARS-CoV-2-positive patient and interviewed them at least 30 days after discharge. We used propensity scores to match patients by baseline characteristics and used linear regression to compare Veterans RAND 12-item physical health component score (PCS) and mental health component scores (MCS), with higher scores indicating better self-reported health., Results: We included 1170 SARS-CoV-2-positive patients and 3716 test-negative controls. The adjusted mean difference for PCS was 0.50 (95% confidence interval [CI]: -0.36, 1.36) and -1.01 (95% CI: -1.91, -0.11) for MCS. Severe disease was strongly associated with worse PCS (β = -7.4; 95% CI: -9.8, -5.1), whereas prior mental health illness was strongly associated with worse MCS (β = -5.4; 95% CI: -6.3, -4.5)., Conclusion: Physical health, assessed by PCS, was similar between matched SARS-CoV-2-positive and SARS-CoV-2-negative patients, whereas mental health, assessed by MCS, was worse during a time when the public experienced barriers to care. These results may inform the development and prioritization of support programs for patients., (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Published: 2023
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24. Economic Evaluation of In-Hospital Clinical Practices in Acute Injury Care: A Systematic Review.

Author: Conombo B, Guertin JR, Tardif PA, Gagnon MA, Duval C, Archambault P, Berthelot S, Lauzier F, Turgeon AF, Stelfox HT, Chassé M, Hoch JS, Gabbe B, Champion H, Lecky F, Cameron P, and Moore L
Subjects: Cost-Benefit Analysis, Delivery of Health Care, Humans, Critical Care, Hospitals
Abstract: Objectives: Underuse of high-value clinical practices and overuse of low-value practices are major sources of inefficiencies in modern healthcare systems. To achieve value-based care, guidelines and recommendations should target both underuse and overuse and be supported by evidence from economic evaluations. We aimed to conduct a systematic review of the economic value of in-hospital clinical practices in acute injury care to advance knowledge on value-based care in this patient population., Methods: Pairs of independent reviewers systematically searched MEDLINE, Embase, Web of Science, and Cochrane Central Register for full economic evaluations of in-hospital clinical practices in acute trauma care published from 2009 to 2019 (last updated on June 17, 2020). Results were converted into incremental net monetary benefit and were summarized with forest plots. The protocol was registered with PROSPERO (CRD42020164494)., Results: Of 33 910 unique citations, 75 studies met our inclusion criteria. We identified 62 cost-utility, 8 cost-effectiveness, and 5 cost-minimization studies. Values of incremental net monetary benefit ranged from international dollars -467 000 to international dollars 194 000. Of 114 clinical interventions evaluated (vs comparators), 56 were cost-effective. We identified 15 cost-effective interventions in emergency medicine, 6 in critical care medicine, and 35 in orthopedic medicine. A total of 58 studies were classified as high quality and 17 as moderate quality. From studies with a high level of evidence (randomized controlled trials), 4 interventions were clearly dominant and 8 were dominated., Conclusions: This research advances knowledge on value-based care for injury admissions. Results suggest that almost half of clinical interventions in acute injury care that have been studied may not be cost-effective., (Copyright © 2021 International Society for Pharmacoeconomics and Outcomes Research, Inc. Published by Elsevier Inc. All rights reserved.)
Published: 2022
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25. Benthos response to nutrient enrichment and functional consequences in coastal ecosystems.

Author: Pascal L, Chaillou G, Nozais C, Cool J, Bernatchez P, Letourneux K, and Archambault P
Subjects: Eutrophication, Nutrients, Ecosystem, Geologic Sediments chemistry
Abstract: As land use intensifies, many coastal waters are becoming enriched with otherwise limiting nutrients, leading to eutrophication. While the extreme effects of eutrophication on benthic communities are well documented, there is still a lack of knowledge about how nutrient enrichment alters biogeochemical interactions occurring at the sediment-water interface. Using ex-situ experiments, this study explores the consequences of nutrient enrichment on sediment characteristics, macrofauna community and benthic fluxes. The quantity of sedimentary organic matter and porewater concentration of NH 4 + , NO x and PO 4 3- increased in enriched treatments. These changes did not affect the macrobenthic community structure. However, macroinfauna buried less deep and increased their ventilation activity. As consequences, nutrient efflux increased, thereby favouring eutrophication processes. These effects were reduced in presence of seagrass, thus illustrating the buffering capacity of seagrass in the context of environmental changes, and particularly, of eutrophication. Overall, this study highlights that the functional consequences of nutrient enrichment involve interconnected processes that are variable in space and time., (Copyright © 2022 Elsevier Ltd. All rights reserved.)
Published: 2022
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26. Adherence to Clinical Practice Guideline Recommendations on Low-Value Injury Care: A Multicenter Retrospective Cohort Study.

Author: Soltana K, Moore L, Bouderba S, Lauzier F, Clément J, Mercier É, Krouchev R, Tardif PA, Belcaid A, Stelfox T, Lamontagne F, Archambault P, and Turgeon A
Subjects: Humans, Quality of Health Care, Retrospective Studies, Guideline Adherence, Practice Guidelines as Topic, Wounds and Injuries therapy
Abstract: Objectives: Low-value clinical practices have been identified as one of the most important areas of excess healthcare spending. Nevertheless, there is a knowledge gap on the scale of this problem in injury care. We aimed to identify clinical practice guideline (CPG) recommendations pertaining to low-value injury care, estimate how frequently they are used in practice, and evaluate interhospital variations in their use., Methods: We identified low-value clinical practices from internationally recognized CPGs. We conducted a retrospective cohort study using data from a Canadian trauma system (2014-2019) to calculate frequencies and assess interhospital variations., Results: We identified 29 low-value practices. Fourteen could be measured using trauma registry data. The 3 low-value clinical practices with the highest absolute and relative frequencies were computed tomography (CT) in adults with minor head injury (n = 5591, 24%), cervical spine CT (n = 2742, 31%), and whole-body CT in minor or single-system trauma (n = 530, 32%). We observed high interhospital variation for decompressive craniectomy in diffuse traumatic brain injury. Frequencies and interhospital variations were low for magnetic resonance imaging, intracranial pressure monitoring, inferior vena cava filter use, and surgical management of blunt abdominal injuries., Conclusions: We observed evidence of poor adherence to CPG recommendations on low-value CT imaging and high practice variation for decompressive craniectomy. Results suggest that adherence to recommendations for the 10 other low-value practices is high. These data can be used to advance the research agenda on low-value injury care and inform the development of interventions targeting reductions in healthcare overuse in this population., (Copyright © 2021 ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.)
Published: 2021
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27. Pre-exposure to Cu 2+ and CuO NPs leads to infection of caged blue mussels, Mytilus edulis L., by pathogenic microalga: Pilot study in the Lower St. Lawrence Estuary (Québec, Canada).

Author: Zuykov M, Kolyuchkina G, Spiers G, Gosselin M, Archambault P, and Schindler M
Subjects: Animals, Canada, Copper, Estuaries, Pilot Projects, Quebec, Microalgae, Mytilus edulis, Water Pollutants, Chemical
Abstract: As evidenced from literature, exposure to non-lethal concentrations of dissolved copper (Cu 2+ ) and copper nanoparticles (CuO NPs) promotes blue mussels susceptibility to various bacterial infections. We study whether pre-exposure (3.5 h) with CuSO 4 (100 μg Cu L -1 ) and CuO NPs (1000 μg Cu L -1 ) will result in infection of M. edulis L. with pathogenic microalga Coccomyxa sp. under field conditions. In May - September 2019, cages were installed in the site Metis-sur-Mer, St. Lawrence Estuary (QC, Canada) where the native mussel population is known to be infected with the pathogen. Untreated and pre-exposed mussels were grown for up to 130 days. Only the mussels pre-exposed to copper were infected by Coccomyxa. This finding allows proposing that occurrences of Coccomyxa-infected mussels worldwide might have an association with water pollution with xenobiotics. Pre-exposure of caged mussels to copper, as a protocol monitoring for other infectious agents, can be recommended to test., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
Published: 2021
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28. Characterization of marine microbial communities around an Arctic seabed hydrocarbon seep at Scott Inlet, Baffin Bay.

Author: Cramm MA, Neves BM, Manning CCM, Oldenburg TBP, Archambault P, Chakraborty A, Cyr-Parent A, Edinger EN, Jaggi A, Mort A, Tortell P, and Hubert CRJ
Subjects: Animals, Geologic Sediments, Hydrocarbons analysis, Methane analysis, Phylogeny, RNA, Ribosomal, 16S, Seawater, Bays, Microbiota
Abstract: Seabed hydrocarbon seeps present natural laboratories for investigating responses of marine ecosystems to petroleum input. A hydrocarbon seep near Scott Inlet, Baffin Bay, was visited for in situ observations and sampling in the summer of 2018. Video evidence of an active hydrocarbon seep was confirmed by methane and hydrocarbon analysis of the overlying water column, which is 260 m at this site. Elevated methane concentrations in bottom water above and down current from the seep decreased to background seawater levels in the mid-water column >150 m above the seafloor. Seafloor microbial mats morphologically resembling sulfide-oxidizing bacteria surrounded areas of bubble ebullition. Calcareous tube worms, brittle stars, shrimp, sponges, sea stars, sea anemones, sea urchins, small fish and soft corals were observed near the seep, with soft corals showing evidence for hydrocarbon incorporation. Sediment microbial communities included putative methane-oxidizing Methyloprofundus, sulfate-reducing Desulfobulbaceae and sulfide-oxidizing Sulfurovum. A metabolic gene diagnostic for aerobic methanotrophs (pmoA) was detected in the sediment and bottom water above the seep epicentre and up to 5 km away. Both 16S rRNA gene and pmoA amplicon sequencing revealed that pelagic microbial communities oriented along the geologic basement rise associated with methane seepage (running SW to NE) differed from communities in off-axis water up to 5 km away. Relative abundances of aerobic methanotrophs and putative hydrocarbon-degrading bacteria were elevated in the bottom water down current from the seep. Detection of bacterial clades typically associated with hydrocarbon and methane oxidation highlights the importance of Arctic marine microbial communities in mitigating hydrocarbon emissions from natural geologic sources., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.)
Published: 2021
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29. Practical advice on monitoring of U and Pu with marine bivalve mollusks near the Fukushima Daiichi Nuclear Power Plant.

Author: Zuykov M, Fowler SW, Archambault P, Spiers G, and Schindler M
Subjects: Animals, Japan, Nuclear Power Plants, Uranium analysis, Bivalvia, Fukushima Nuclear Accident, Plutonium analysis, Radiation Monitoring, Water Pollutants, Radioactive
Abstract: Following the Fukushima Daiichi nuclear power plant accident in 2011, some marine radionuclide monitoring studies report a lack of evidence for contamination of Japanese coastal waters by U and Pu, or state that marine contamination by them was negligible. Nevertheless, Fukushima-derived U and Pu were reported as associated with Cs-rich microparticles (CsMPs) found in local soil, vegetation, and river/lake sediments. Over time, CsMPs can be transported to the sea via riverine runoff where actinides, as expected, will leach. We recommend establishing a long-term monitoring of U and Pu in the nearshore area of the Fukushima Prefecture using marine bivalve mollusks; shells, byssal threads and soft tissues should all be analyzed. Here, based on results from Th biosorption experiments, we propose that U and Pu could be present at concentrations several times higher in shells with a completely destroyed external shell layer (periostracum) than in shells with intact periostracum., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2019 Elsevier Ltd. All rights reserved.)
Published: 2020
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30. Changes in infaunal assemblage structure influence nutrient fluxes in sediment enriched by mussel biodeposition.

Author: Lacoste É, Weise AM, Lavoie MF, Archambault P, and McKindsey CW
Subjects: Animals, Aquaculture, Aquatic Organisms physiology, Quebec, Biota, Geologic Sediments chemistry, Mytilus edulis physiology, Nutrients analysis
Abstract: Although many studies have described the influence of bivalve aquaculture on the benthic environment, effects on benthic functional diversity are poorly known, as are links with ecosystem processes. We investigated the response of a benthic ecosystem in terms of taxonomic and functional diversity (infauna >500 μm), biogeochemical indicators (organic matter content, redox potential, sulfides level, bacteria) and metabolism (nutrient fluxes), subjected to various levels of mussel biodeposition as a general model of organic enrichment. Results show that local benthic conditions may recover fairly quickly depending on environmental conditions whereas modifications of the benthic community structure persist over a longer time scale with an impact on benthic ecosystem functioning. Fauna-mediated oxidation of the sediment likely increased nitrogen recycling through nitrification whereas binding and release of phosphorus to the water column seems to be driven by more complex processes. Results highlight the importance of species identity (ecological traits) on biogeochemical cycling and solute exchange across the sediment-water interface, with implications for the ecological functioning of exploited areas., (Crown Copyright © 2019. Published by Elsevier B.V. All rights reserved.)
Published: 2019
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31. Bioturbation activity of three macrofaunal species and the presence of meiofauna affect the abundance and composition of benthic bacterial communities.

Author: Lacoste É, Piot A, Archambault P, McKindsey CW, and Nozais C
Subjects: Animals, Bacteria classification, Biodiversity, Ecology, Ecosystem, Environmental Monitoring, Geologic Sediments chemistry, Aquatic Organisms physiology, Bacteria growth & development, Invertebrates physiology, Water Microbiology
Abstract: Given concerns of increasing rates of species extinctions, the relationship between biodiversity and ecosystem functioning has become a major research focus over the past two decades. Many studies have shown that biodiversity per se (e.g. species richness) or species-specific traits may be good predictors of changes in ecosystem function. Although numerous studies on this subject have focused on terrestrial systems, few have evaluated benthic marine systems. We used the Limecola balthica community as a model to test whether the number or identity of three well-studied macrofaunal species influence the sediment bacterial compartment, which drives important biogeochemical processes and influence ecosystem functioning. We also investigated the poorly known role of meiofauna in the interactions between macrofauna and bacteria. Eight combinations of 0-3 species were maintained in microcosms for 34 days in the presence or absence of meiofauna. The abundance and composition of the bacterial community, defined by the relative percentage of cells with a high (HNA) vs low (LNA) nucleic acid content, were measured. Species identity of macrofauna was a better indicator of changes in the microbial compartment than was species richness per se. In particular, the gallery-diffuser behaviour of the polychaete Alitta virens likely induced strong changes in sediment physical and geochemical properties with a major impact on the bacterial compartment. Moreover, the presence of meiofauna modulated the influence of macrofauna on bacterial communities. This study provides evidence that species identity provides greater explanatory power than species richness to predict changes in the bacterial compartment. We propose that multi-compartment approaches to describe interactions amongst different size classes of organisms and their ecological roles should be further developed to improve our understanding of benthic ecosystem functioning., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
Published: 2018
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32. Acute visual loss secondary to ruptured sinus mucoceles.

Author: Peng SL, Archambault P, Conti T, and Arthurs B
Subjects: Acute Disease, Adult, Blindness physiopathology, Drainage, Female, Humans, Intraocular Pressure, Male, Middle Aged, Mucocele diagnostic imaging, Mucocele surgery, Orbital Diseases diagnostic imaging, Orbital Diseases surgery, Paranasal Sinus Diseases diagnostic imaging, Paranasal Sinus Diseases surgery, Rupture, Spontaneous, Tomography, X-Ray Computed, Visual Acuity physiology, Blindness etiology, Mucocele complications, Orbital Diseases complications, Paranasal Sinus Diseases complications
Published: 2016
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33. Influence of intertidal recreational fisheries and 'bouchot' mussel culture on bivalve recruitment.

Author: Toupoint N, Barbier P, Tremblay R, Archambault P, McKindsey CW, Winkler G, Meziane T, and Olivier F
Subjects: Animals, Aquaculture methods, Ecosystem, Environmental Monitoring, France, Bivalvia, Fisheries statistics & numerical data
Abstract: In coastal environments, fishing and aquaculture may be important sources of disturbance to ecosystem functioning, the quantification of which must be assessed to make them more sustainable. In the Chausey Archipelago, France, recreational fishing and commercial shellfish farming are the only two evident anthropogenic activities, dominated by bivalve hand-raking and 'bouchot' mussel culture, respectively. This study evaluates the impact of both activities on bivalve recruitment dynamics by comparing primary recruitment intensity (short-term effect) and recruitment efficiency (medium-term effect) by sampling bivalves in reference (undisturbed) and disturbed (i.e. subjected to hand-raking or in 'bouchot' mussel culture areas) parcels throughout and at the end of the recruitment season, respectively. Specific hypotheses evaluated were that (H1) bivalve hand-raking negatively affects bivalve recruitment and that (H2) 'bouchot' mussel culture promotes bivalve recruitment. Patterns in bivalve community structure in reference parcels (i.e. natural pattern) differed between initial and final recruitment, underlining the great importance of early post-settlement processes, particularly secondary dispersal. Primary recruitment intensity was inhibited in hand-raking parcels whereas it was promoted in 'bouchot' mussel culture parcels, but the effect on recruitment efficiency was muted for both activities due to post-settlement processes. Nevertheless, the importance of effects that occur during the first step of recruitment should not be ignored as they may affect bivalve communities and induce immediate consequences on the trophic web through a cascade effect. Finally, it is highlighted that hand-raking damages all life stages of the common cockle Cerastoderma edule, one of the major target species, suggesting that this activity should be managed with greater caution than is currently done., (Copyright © 2016 Elsevier Ltd. All rights reserved.)
Published: 2016
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34. Maximizing post-stroke upper limb rehabilitation using a novel telerehabilitation interactive virtual reality system in the patient's home: study protocol of a randomized clinical trial.

Author: Kairy D, Veras M, Archambault P, Hernandez A, Higgins J, Levin MF, Poissant L, Raz A, and Kaizer F
Subjects: Cost-Benefit Analysis, Exercise Therapy economics, Humans, Quality of Life, Recovery of Function, Single-Blind Method, Stroke Rehabilitation economics, Telerehabilitation economics, Exercise Therapy methods, Home Care Services, Stroke physiopathology, Stroke Rehabilitation methods, Telerehabilitation methods, Upper Extremity physiopathology, User-Computer Interface
Abstract: Background: Telerehabilitation (TR), or the provision of rehabilitation services from a distance using telecommunication tools such as the Internet, can contribute to ensure that patients receive the best care at the right time. This study aims to assess the effect of an interactive virtual reality (VR) system that allows ongoing rehabilitation of the upper extremity (UE) following a stroke, while the person is in their own home, with offline monitoring and feedback from a therapist at a distance., Methods/design: A single-blind (evaluator is blind to group assignment) two-arm randomized controlled trial is proposed, with participants who have had a stroke and are no longer receiving rehabilitation services randomly allocated to: (1) 4-week written home exercise program, i.e. usual care discharge home program or (2) a 4-week home-based TR exercise program using VR in addition to usual care i.e. treatment group. Motor recovery of the UE will be assessed using the Fugl-Meyer Assessment-UE and the Box and Block tests. To determine the efficacy of the system in terms of functional recovery, the Motor Activity Log, a self-reported measure of UE use will be used. Impact on quality of life will be determined using the Stroke Impact Scale-16. Lastly, a preliminary cost-effectiveness analysis will be conducted using costs and outcomes for all groups., Discussion: Findings will contribute to evidence regarding the use of TR and VR to provide stroke rehabilitation services from a distance. This approach can enhance continuity of care once patients are discharged from rehabilitation, in order to maximize their recovery beyond the current available services., (Copyright © 2015 Elsevier Inc. All rights reserved.)
Published: 2016
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35. Dose-dependent response of a benthic system to biodeposition from suspended blue mussel (Mytilus edulis) culture.

Author: Robert P, McKindsey CW, Chaillou G, and Archambault P
Subjects: Animals, Oxygen analysis, Seawater chemistry, Water Pollution statistics & numerical data, Aquaculture, Environmental Monitoring, Geologic Sediments chemistry, Mytilus edulis physiology, Water Pollutants analysis
Abstract: This study reports the results of a field experiment using benthic mesocosms that examined dose-dependent effects of mussel biodeposition on the benthic environment. Mesocosms were placed in the natural sea bottom and subjected to one of eight levels of biodeposition (from 0 to 1400 mussels m⁻²). Most analyses indicated non-linear (i.e., threshold) effects. Sediment characteristics changed significantly between 200 and 400 mussels m⁻² as did multivariate community structure. Community structure effects were characterised by changes in abundances of species that are very sensitive or tolerant to organic loading. The multivariate AZTI Marine Biotic Index (M-AMBI) indicated that the benthic status changed from High to Good in all mesocosms receiving biodeposits. Sediments acted as a sink for oxygen (O₂), but results suggest O₂ sediment demand was not sensitive enough to evaluate organic loading impacts. Results from this and improved experiments can be used to determine the environmental carrying capacity of sites for bivalve culture., (Copyright © 2012 Elsevier Ltd. All rights reserved.)
Published: 2013
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36. Responses of benthic macrofauna and biogeochemical fluxes to various levels of mussel biodeposition: an in situ "benthocosm" experiment.

Author: Callier MD, Richard M, McKindsey CW, Archambault P, and Desrosiers G
Subjects: Analysis of Variance, Animals, Dose-Response Relationship, Drug, Linear Models, Oxygen analysis, Polychaeta metabolism, Population Dynamics, Quebec, Bivalvia metabolism, Ecosystem, Feces chemistry, Geologic Sediments analysis, Polychaeta drug effects
Abstract: An in situ experiment was done to evaluate the dose-dependent response of mussel biodeposition on benthic communities and biogeochemical fluxes. Natural benthic communities were exposed to 7 different levels of mussel biodeposition (equivalent to that produced by 0-764 mussels m(-2)) over 50 days. Benthic communities responded as predicted from the Pearson, T.H., Rosenberg, R., 1978. Macrobenthic succession in relation to organic enrichment and pollution of the marine environment. Oceanogr. Mar. Biol. Annu. Rev. 16, 229-311 model of organic enrichment. Total abundance and species richness decreased with increasing biodeposition. The abundance and biomass of opportunistic species (Capitella spp.) increased in the mesocosms subject to the greatest biodeposition. Sensitive species Tellina agilis and Pherusa plumosa tended to decrease in abundance and biomass with increasing biodeposition. The biotic index M-AMBI responded clearly to increased biodeposition and may be a useful tool for assessing the effect of mussel biodeposition on the benthic environment. These results are important for the construction of predictive models for determining environmental carrying capacity for bivalve aquaculture.
Published: 2009
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37. GATA-1 associates with and inhibits p53.

Author: Trainor CD, Mas C, Archambault P, Di Lello P, and Omichinski JG
Subjects: Animals, Binding Sites, Cell Differentiation, Cell Line, Tumor, Cell Survival, DNA chemistry, DNA metabolism, Erythroid Cells cytology, Erythroid Cells metabolism, GATA1 Transcription Factor chemistry, GATA1 Transcription Factor genetics, Humans, In Vitro Techniques, Macromolecular Substances, Mice, Mutagenesis, Site-Directed, Nuclear Magnetic Resonance, Biomolecular, Protein Interaction Domains and Motifs, Recombinant Fusion Proteins chemistry, Recombinant Fusion Proteins genetics, Recombinant Fusion Proteins metabolism, Transcriptional Activation, Tumor Suppressor Protein p53 chemistry, Tumor Suppressor Protein p53 genetics, Zinc Fingers, GATA1 Transcription Factor metabolism, Tumor Suppressor Protein p53 antagonists & inhibitors, Tumor Suppressor Protein p53 metabolism
Abstract: In addition to orchestrating the expression of all erythroid-specific genes, GATA-1 controls the growth, differentiation, and survival of the erythroid lineage through the regulation of genes that manipulate the cell cycle and apoptosis. The stages of mammalian erythropoiesis include global gene inactivation, nuclear condensation, and enucleation to yield circulating erythrocytes, and some of the genes whose expression are altered by GATA-1 during this process are members of the p53 pathway. In this study, we demonstrate a specific in vitro interaction between the transactivation domain of p53 (p53TAD) and a segment of the GATA-1 DNA-binding domain that includes the carboxyl-terminal zinc-finger domain. We also show by immunoprecipitation that the native GATA-1 and p53 interact in erythroid cells and that activation of p53-responsive promoters in an erythroid cell line can be inhibited by the overexpression of GATA-1. Mutational analysis reveals that GATA-1 inhibition of p53 minimally requires the segment of the GATA-1 DNA-binding domain that interacts with p53TAD. This inhibition is reciprocal, as the activation of a GATA-1-responsive promoter can be inhibited by p53. Based on these findings, we conclude that inhibition of the p53 pathway by GATA-1 may be essential for erythroid cell development and survival.
Published: 2009
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38. 1998 ISEK Congress Keynote Lecture: Multi-muscle control in human movements. International Society of Electrophysiology and Kinesiology.

Author: Feldman AG, Levin MF, Mitnitski AM, and Archambault P
Subjects: Abdominal Muscles physiology, Adult, Arm physiology, Electromyography, Electrophysiology, Female, Humans, International Cooperation, Leg physiology, Male, Middle Aged, Societies, Medical, Movement physiology, Muscle, Skeletal physiology
Abstract: It has been suggested that the coordination of the activity of multiple muscles results from the comparison of the actual configuration of the body with a referent configuration specified by the nervous system so that the recruitment and gradation of the activity of each skeletal muscle depend on the difference between these two configurations. Active movements may be produced by the modification of the referent configuration. The hypothesis predicts the existence of a global minimum in electromyographic (EMG) activity of multiple muscles during movements involving reversals in direction. This prediction was tested in five subjects by analysing movements resembling the act of reaching for an object placed beyond one's reach from a sitting position. In such movements, initially sitting subjects raise their body to a semi-standing position and then return to sitting. Consistent with the hypothesis is the observation of a global minimum in the surface EMG activity of 16 muscles of the arm, trunk and leg at a specific phase of the movement. When the minimum occurred, EMG activity of each muscle did not exceed 2-7% of its maximal activity during the movement. As predicted, global EMG minima occurred at the phase corresponding to the reversal in movement direction, that is, during the transition from raising to lowering of the body. The global EMG minimum may represent the point at which temporal matching occurs between the actual and the referent body configurations. This study implies a specific link between motor behavior and the geometric shape of the body modified by the brain according to the desired action.
Published: 1998
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39. Incidence of retinopathy of prematurity among infants weighing 2000 g or less at birth.

Author: Archambault P and Gomolin JE
Subjects: Canada, Humans, Infant, Newborn, Retrospective Studies, Infant, Low Birth Weight, Retinopathy of Prematurity epidemiology
Abstract: A retrospective study was carried out to determine the incidence of retinopathy of prematurity (ROP) among 157 neonates who weighed 2000 g or less at birth and who were examined at a referral centre for critically ill newborns between January 1983 and December 1985. Overall, 24 cases (15%) of ROP were detected, 18 (75%) among neonates with a birth weight of 1000 g or less. The incidence of ROP was more than eight times higher among neonates in this birth weight category than among those who weighed between 1001 and 2000 g. Grade I ROP accounted for 16 cases (67%), grade II for 7 cases (29%). Only one case (4%) of grade IV ROP was diagnosed, in an infant who weighed 1020 g at birth.
Published: 1987

40. [Acceptability of the Hemoccult test in general medical practice. Results of a pilot study].

Author: Archambault F, Durand G, Faivre J, Voilquin JP, Archambault P, Riou F, Ageorges P, Archambault ML, Delville JM, and Fesneau M
Subjects: Aged, Clinical Trials as Topic, Family Practice, Female, France, Humans, Male, Mass Screening, Middle Aged, Pilot Projects, Colorectal Neoplasms prevention & control, Occult Blood, Patient Acceptance of Health Care statistics & numerical data
Abstract: In view of preparing a controlled trial to assess the efficacy of screening for colorectal cancer by fecal occult blood testing in reducing cancer mortality, a pilot study was performed to evaluate the acceptability rate of the Hemoccult test in non selected subjects consulting in a general practice. 566 subjects aged 45 to 74 years from two small towns, Neuville-aux-Bois (Loiret) and Vicherey (Vosges) were included in the study. The screening test was proposed by GPs to 89.2% of their patients; of these, 5.6% refused the test and 9.4% did not return it. Of the tests carried out, 80.8% were performed spontaneously, and 19.2% after a recall letter. Acceptability depended neither on age or on sex. The patients' confidence in his GP was the most important acceptability factor (60%), followed by explanations the GP had provided, and ease of application. The results suggest that after receiving the correct information, a GP will succeed in prescribing the Hemoccult test to most high-risk subjects and that acceptability then proves excellent. Experience drawn from the pilot study has been very useful in conceiving the on-going controlled trial in Burgundy.
Published: 1989

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